Persingahan Pelosi di Suriah ditentang sejak awal oleh pemerintah Presiden AS George W. Bush, yang menuduh Damaskus menaja terorisme dan mengatakan negara itu mesti dikucilkan dari masyarakat internasional.
Pelosi's Syrian stopover was opposed from the start by the Bush administration, which accuses Damascus of sponsoring terrorism and says it should be isolated from the international community.