Dari jaringan solid, biasanya jaringan dicincang, lalu diber enzim pencerna seperti tripsin atau kolagenase untuk menghilangkan matriks ekstraselular yang mengikat atau menyatukan sel.
To get cells from solid tissue, tissues are usually chopped, then digestive enzymes, such as tripsin or collagenase are added to remove extracellular matrix which binds or unites cells together.