Term: Mona Lisa, Description: Painting by Leonardo da Vinci, Question: Is the Mona Lisa based on a real person?, Answer:Yes
Fact1: There are two main theories about the origin of the Mona Lisa. Fact2: The first is that a wealthy noblewoman, the wife of one of Leonardo's friends, sat as the model. Fact3: Another popular theory is that Leonardo painted her as a cross-gendered self portrait. 