The article is silent on the price of Rituxan. Since the company is investing a significant sum to research an additional use, the price is worth mentioning. The article does a good job of sketching the benefits shown in this research. Focusing on the clinical endpoint of relapse, and using percentages of relapse with the drug and the placebo, makes it easy for readers to understand. The article explores the issue of whether Rituxan may suppress the immune response too much, making the patient vulnerable to other diseases. It also explains how this effect has been observed in the drug Tysabri, a different immune suppressant used for MS. This article is based on published results of a Phase II trial published in the New England Journal of Medicine. The news article does a decent job emphasizing the preliminary nature of the findings, and that larger trials are needed to ensure safety, efficacy and long-term benefits. The article does nothing to exaggerate the severity or consequences of MS. The reporter draws on the journal article and the accompanying editorial. Sources interviewed include the primary author, one medical expert representing the National Multiple Sclerosis Society and one clinician who treated some patients in the study but was not an author. This is sufficient sourcing. It is worth pointing out here, however, that Genentech and Biogen Idec, makers of Rituxan, are “Corporate Star” supporters of the National Multiple Sclerosis Society. The article states that six other drugs, all with shortcomings, are available to treat relapsing-remitting MS. The article makes clear that the drug is currently on the market and approved for other uses. But it did not state whether Rituxan is, or may become, used off-label for relapsing-remitting MS. And, as noted in our summary comment below, there are issues surrounding off-label use that could have been addressed. The article makes clear that the drug is on the market and used for related conditions, but its use in relapsing-remitting MS patients is being explored in this research. There is no evidence the article draws from a press release.
MS therapy shows promise in test