Friederike was born in Darmstadt, the eldest daughter of Prince George William of Hesse-Darmstadt, second son of Louis VIII, Landgrave of Hesse-Darmstadt, and Countess Maria Louise Albertine of Leiningen-Falkenburg-Dagsburg. _She_ married Duke Charles of Mecklenburg-Strelitz on 18 September 1768 in Darmstadt. <sep>, Pronoun: She <sep>, A: Friederike <sep>, B: Countess Maria Louise Albertine