Sentence 1: Sandra noticed the medicines she sold didn't matter. 
 Sentence 3: She put them in brightly colored boxes 
 Sentence 4:  Many people got better on their own by drinking her remedies 
 Sentence 5:  The ones who didn't, didn't complain 
 Option 1: She started replacing the concoctions with water. 
 Option 2: After replacing them with water, people started asking for refunds.