Donald C. Chang
Donald Choy Chang (; 1942) is a founding professor of the Hong Kong University of Science and Technology (HKUST). He was also the founding President of the Biophysical Society of Hong Kong. He is currently Professor Emeritus and Adjunct Professor in HKUST, and Council Member of Hong Kong Institute of Science (HKIS). Chang has wide research interests. He was an experimental physicist by training; but his publication ranges from nuclear magnetic resonance, biophysics and quantum physics. Detection of cancer using nuclear magnetic resonance (NMR) Chang is an early pioneer in the study of the physical properties of water in cells using spin-echo nuclear magnetic resonance (NMR) techniques. When Donald Chang was working in the Physics Department at Rice University, he built a home-made NMR spectrometer to measure the relaxation times (T1 and T2) of water in normal cells/tissues, cancer cells and simply in free water samples. His major collaborator at that time was the physiologist, C.F. Hazlewood, in the Baylor College of Medicine. Many publications related to this work were published with Hazlewood. Chang and his team gave the first time report that the relaxation time of cellular water (heart muscle cells in this case) is much shorter than the