Sabretooth
Sabretooth or sabertooth may refer to:

Animals 
 Saber-toothed cat, several prehistoric felines
 Smilodon, a prehistoric genus of felidae
 Sabertooth fish, a deep-sea fish found in the tropics
 Sabre-toothed blenny, Aspidontus taeniatus, a variety of fish that lives deep underwater in the benthic zone
 Sabertooth blenny, Plagiotremus azaleus, a species of combtooth blenny in coral reefs in the eastern Pacific Ocean
 Sabertooth salmon, Oncorhynchus rastrosus, an ancient species of salmon
 Sabretooth tetra, the Payara, Hydrolycus scomberoides, a species of gamefish in the Orinoco River in Venezuela and in the Amazon basin
 Marsupial sabretooth, Thylacosmilus, a genus of sabre-toothed metatherian predators from the Miocene period

Sports 
 San Jose SaberCats, an Arena Football League team
 Sabretooth (mascot), the mascot for the Buffalo Sabres National Hockey League team

Fiction 
 Sabretooth (comics), a Marvel Comics supervillain, and arch-enemy of Wolverine.
 Sabretooth (film), a 2002 made-for-TV movie
 Sabre-Tooth, a 1966 book by Peter O'Donnell featuring the character Modesty Blaise
 Captain Sabertooth, a fictional pirate that is the main character in a number of theatre plays by the Norwegian singer and actor Terje Formoe

Other uses 
 SABERTOOTH, a protein sequence and structure alignment algorithm
 Sabertooth Games, a now defunct Memphis, Tennessee based game company, founded in 2001