Genetic alterations in syndromes with oral manifestations
A female patient aged 14 reported to our out-patient department for painful teeth. On extraoral examination, her physique was abnormal with tall stature [], dolichostenomelia (positive wrist sign) and dolichocephalic face [], arachnodactyly (spidery finger and long digits) [Figure and ]. Intraorally, high arched palate along with decayed tooth was identified.\nCardiac evaluation revealed aortic dilatation. These phenotypical features had partial manifestations of Marfan's syndrome (MFS). Appropriate genes were mapped by reviewing the literature.