Primary pulmonary rhabdomyosarcoma in children: Report of three cases with review of literature
A female child aged 3 years, presented with history of dyspnea, fever, and cough for 2 months. She was diagnosed to have right-sided pneumothorax which did not improve following insertion of intercostal drainage. Later, CT scan showed mass lesion in right lower lobe with pneumothorax. She underwent exploratory thoracotomy with subtotal excision of right lower lobe mass. Histopathology showed spindle cell sarcoma [Figures and ] and IHC revealed cells positive for desmin [], focally for MyoD 1 [] and H-caldesmon, suggestive of embryonal RMS of anaplastic type. Metastatic workup was negative. Parents refused adjuvant chemotherapy and child was disease free for 7 months.