Cherubism: Report of a case
A 4-year-old boy presented with painless bilateral swelling of the mandible. When the boy was about 2 years old, the parents had noticed a change in facial symmetry of the face, which later on became more marked []. Intraorally the alveolar ridges were swollen at the angle region and were firm on palpation. Patient had moderate bilateral submandibular lymph node enlargement. Physical and mental development was normal. Patient's parents are healthy had no siblings and none of their relatives had facial deformities.\nRadiographically, the mandible showed a multilocular radiolucency with thin and expanded cortices, including the body and posterior rami bilaterally. The condyle and the condylar neck appeared normal. Maxilla was not involved. The second permanent molar bud was missing considering the age. Radiographically and clinically, symmetric involvement was evident []. CT scan revealed expansile remodeling with multiple osteolytic areas in the mandible []. Laboratory tests, which included serum calcium, phosphorous, alkaline phosphatase and parathyroid hormone were normal.\nBiopsy from the central area of both right and the left rami were taken. Histopathological examination showed fibrovascular collagenous connective tissue with dispersed giant cells []. Patient was recalled after 4 years and patient was asymptomatic; however, the facial asymmetry was evident []. Follow-up orthopantomogram also showed multilocular radiolucencies within the posterior body and rami of mandibular region bilaterally []. As the condition tends to resolve around 15 years of age, patient is kept under periodic follow-up.