Harlequin ichthyosis: Case report
A 31-year-old pregnant woman was admitted to the Zabol Amir-Al-Momenin hospital for her third pregnancy due to preterm, premature rupture of membrane and obstetric pain. Gestational age was approximately 30 weeks and 1 day based on both the first day of the last menstrual period and ultrasound. No remarkable complication was noted in the last ultrasound examination at 28 weeks of pregnancy. A female baby with HI was born via normal spontaneous vaginal delivery. Her birth weight, length, and head circumference was 2.1 kg, 44 cm, and 29 cm, respectively []. Parents had a distant relation and had two other normal healthy children. Thick skin with deep fissures, general hyperkeratinization, cyanosis, flat fontanels, ectropion, immature eyes and auricles, eclabium, bradycardia, bradypnea, and moaning were noted in the physical examination. Antibiotic therapy and conservative treatments were started after admission to the neonatal intensive care unit. However, the parents self-discharged their newborn daughter at the same day after birth.