Cystic fibrosis of pancreas and nephrotic syndrome: a rare association
A two-year-old male patient was referred to Dicle University Department of Pediatric Pulmonology Unit. In history, he had diagnosed as CF due to chronic diarrhea, while he was two months of age. During follow-up, no pulmonary involvement was observed; however, eight months prior to this study a decrease in urine volume was detected, as well as, edemas in the patient's face and bilateral lower extremities.\nThe patient's medical history included an upper respiratory tract infection two weeks prior. Physical examination revealed the following: temperature, 36.8℃; pulse, 84/min; blood pressure, 94/50 mmHg (50th percentile); and edemas in the patient's face and bilateral lower extremities. Other system examinations were normal.\nLaboratory examinations results revealed the following in diagnosis time; sweat test was repeated 122 mmol/L, liver function tests and complement factors 3 and 4 were normal, antinuclear antibody was negative, albumin was 0.6 mg/dL, total cholesterol was 220 mg/dL, urea was 16 mg/dL, and creatinine was 0.4 mg/dL. Twenty-four-hour urine collection was found nephrotic proteinuria (>960 mg/m2/day) and the patient was diagnosed with NS and started oral corticosteroids 2 mg/kg/day, 6-week therapy and achieved remission. The patient was regarded as minimal change disease. The patient is still in remission and being followed for NS.