Generalized Dowling-Degos Disease: Case Reports
A 58-year-old man (first son of the proband) was presented with reticulate hyperpigmented skin lesions over the face, chest, back, axillae and flexures since adolescence. Initially, the lesions, which first started over the face, were raised above the skin surface and were small. Gradually, these lesions progressed to form pits filled with blackish material. He developed similar lesions over the back and chest over the next year. There was no history of other skin diseases. His father, all his siblings and their offspring were affected with the same disease. His general physical examination was within normal limits. Skin examination revealed open comedone-like lesions and multiple pits of varying sizes distributed over the face, neck and limbs. The face and neck were more severely affected when compared to the trunk and limbs. There was diffuse reticulate pigmentation over the face, axillae, inguinal region and back. The rest of the skin examination was unremarkable.