Granular cell tumor of the tongue: Report of a case
A 40-year-old male reported with a chief complaint of painless swelling on the left lateral border of tongue since one year. The swelling was initially small in size and slowly progressed to present size of 1 × 1 cm. The patient gave no history of trauma, pain, bleeding, ulceration or pus discharge. Past dental history, family history and drug history was not contributory. Patient gave history of tobacco chewing and bidi smoking (4-5/day) since 15 years.\nIntraoral examination revealed a well circumscribed soft tissue swelling with a smooth surface, oval shape and measuring 1 × 1 cm approximately on the left posterolateral aspect of lingual dorsum. The swelling was pinkish pale white in color. Characteristic loss of the gustatory papillae of the overlying mucosa was seen.\nOn palpation, swelling was firm, mildly tender, adherent to the underlying structures with no regional lymphadenopathy.\nA clinical diagnosis of Fibroma was made. Routine hematological investigations revealed normal values. Excisional biopsy was performed and specimen was sent for histopathological examination.\nGross examination revealed a soft tissue mass, pale creamish to brownish in color, with well defined borders, 1 × 1 cms, oval in shape and soft in consistency [].\nHistopathological examination of H and E stained section revealed lesional tissue consisting of parakeratinized stratified squamous epithelium showing pseudoepitheliomatous hyperplasia The underlying connective tissue shows tumor cells arranged in the form of nests and ribbons [Figures and ]. These neoplastic cells are large polygonal in shape with indistinct cell borders, abundant coarse eosinophilic granular cytoplasm and pale eccentric nuclei, some of which are vesicular. These neoplastic cells exhibit mild hyperchromatism and pleomorphism []. The adjacent fibro-cellular stroma consists of collagen fibers, fibroblasts and few endothelium lined blood capillaries.\nBased on histopathological findings the final diagnosis of GCT was made.