Comparison of Tc-99m MDP and Sm-153 EDTMP bone scan
We report a case of a 72-year-old male patient with carcinoma prostrate, who had bilateral orchidectomy in 2002. In 2009, he had reactivation of bone pain and was detected to have cervical vertebral metastases. Radiation was given up to 30 Gy to the vertebrae. The patient was on hormone since then and had monthly Zolendronic acid injection i.v. (14 injections). Serum prostate specific antigen (PSA) was increased (58.8 ng/ml). In 2010, he developed diffuse body ache and 99mTc methylene diphosphonate (MDP) scan revealed multiple uptake in axial and appendicular skeleton []. Radiogram of chest revealed no pulmonary metastases [].\nThe patient was given a dose of 40 mCi of 153Sm EDTMP intravenously. After 96 hours, whole body images were acquired (512×512 matrix) – anterior and posterior views. The scan was compared with 99mTc MDP bone scan. Both revealed abnormal concentration in dorsolumbar vertebrae and skull, besides pelvis and ribs []. The metastases concentrate 153Sm EDTMP – a prerequiirement for fixed pain relief. The patient had pain relief over a period of 1–2 weeks.