Stomach metastasis of breast carcinoma mimicking primary gastric neoplasm on fluorodeoxy glucose–positron emission tomography–computed tomography
We present fluorodeoxy glucose positron emission tomography–computed tomography (FDG-PET/CT) findings in a 53-year-old woman, a case of ductal breast carcinoma, post-modified radical mastectomy status. Six years after surgery, she was found to have skeletal metastases and PET/CT was performed to evaluate baseline pre-chemotherapy disease status. PET/CT, along with skeletal metastases, revealed a hypermetabolic stomach thickening [], which was reported as a possible primary gastric neoplasm. The patient had no abdominal symptoms. Endoscopic biopsy of this lesion demonstrated presence of breast carcinoma metastasis with estrogen receptor positivity []. Stomach metastasis of breast carcinoma is very rare.[] Our case suggests that it is difficult to distinguish a stomach metastasis of breast cancer from a primary gastric cancer on the basis of clinical and imaging features. However, this differential diagnosis must be kept in mind, and it is important to make such distinction because of its implications on patient management.\nPhotomicrograph of the pathology slides (A) shows ductal carcinoma of the breast. The neoplastic cells marked with arrows in B and C demonstrate positive staining for cytokeratin-7 (CK-7) and estrogen receptors (ER), respectively. Final diagnosis of stomach metastasis of breast carcinoma was made and the patient was started on hormonal therapy.