Angiomyofibroblastoma of the vulva
A 40-year-old woman came to our outpatient clinic with a painless vulvar mass that started few months before, which had gradually grown. At first, she ignored the mass, because it did not have any symptoms, despite its enlargement. However, she decided that she had to go the hospital because the size of mass enlarged and she feel uncomfortable. She did not had any previous gynecological surgery and her laboratory data (complete blood cell count, creatinine, coagulation, selology) showed no significant abnormalities. Physical examination showed a hardened mass of about 2 cm in diameter of the right labia majora with tense elastic consistency. On pelvic examination, the uterus and bilateral ovary showed no abnormalities and pelvic lymph nodes were not swollen. First, the clinical impression of the mass was bartholin cyst or lipoma. Therefore, we decided that simple tumor excision was the proper treatment for the mass, and it was subsequently performed one month after as her second visit. On gross examination, the mass was well circumscribed and had a soft to firm legion with a size of about 2×2 cm; no more grown compare to one month ago as her first visit. The color of the mass cut surface was light gray to tan homogeneously. Surgical margins of the lesion were clear. Microscopically, the tumor demonstrated admixture of hypocelluar and hypercellular area in the background of edematous stroma. The abundant vessels of various wall thickness were distributed in the collagenous stroma. The stroma consisted of spindle and ovoid stromal cells with eosinophilic cytoplasm and no mitotic features or significant nuclear atypia (). The tumor also has estrogen and/or progesterone receptors and has immunoreactivity for vimentin ().\nCurrently, the patient was follow up was lost for about 7 years and we decided to follow up with her by a telephone call. She said she almost forgot about the mass removal event and there is no evidence of recurrence.