Case for diagnosis
70-years-old white female presented a five-year evolution of recurrent and asymptomatic\ntense blisters with serous content on the second and third left fingers, which\ndisappeared without scarring. She denied triggering factors such as trauma.\nComorbidities, hypertension and type 2 diabetes mellitus for 20 years treated\nirregularly with antihypertensives and oral hypoglycemics.\nWe found on examination of the patient a tense blister with serous content, 2 cm in\ndiameter, located on the distal phalanx of the second left finger ( and ). There was\nevidence of distal hypoesthesia on the hands and feet associated with normal peripheral\npulses. No signs of local inflammation.\nHistologic examination revealed intraepidermal cleavage, reepithelialization and few\ninflammatory cells ().