Ichthyosis associated with widespread tinea corporis: report of three\ncases
A 27-year-old female patient, with Sjögren Larsson Syndrome (congenital ichthyosis\nassociated to spasticity), had been followed since 2003. She was on Acitretin since\n2004 and presented with sudden worsening. From 2008 on, she had onycholysis and\nsubungual hyperkeratosis on toenails. She was on ciclopirox olamine nail lacquer and\nketoconazole cream for more than 2 years with mild improvement. In September 2011 her\nmother reported severe worsening of ichthyosis, despite regular use of Acitretin.\nClinical examination demonstrated lamellar desquamation of the lower limbs,\nill-defined erythematous patches, and round scaly lesions on trunk and left leg\n(). Direct mycological examination\nshowed hyaline septate hyphae and the culture was positive for T. rubrum\n(). Skin biopsy\ndemonstrated several hyphae within the stratum corneum. Terbinafine 250 mg qd for 30\ndays led to clearance of the erythematous lesions, slight scaling persisted due to\nbaseline ichthyosis ().