Lymphocytic hypophysitis masquerading as pituitary adenoma
A 15-year-old girl presented to endocrinology OPD with history of headache, amenorrhea, and polyuria for past 4 months. On initial evaluation, she had suppressed follicular stimulating hormone (<0.01 mIU/ml), high prolactin levels (110.85 ng/ml) and DI. Magnetic resonance imaging of sella was suggestive of pituitary macroadenoma with partial compression over optic chiasma [Figures and ]. Patient underwent surgical decompression. Yellowish firm tissue was evacuated and xanthochromic fluid was aspirated. Histopathology was suggestive of LH. Her menstrual cycles resumed postoperatively after 4 months, the prolactin levels normalized; however, she continues to have DI and is on desmopressin spray.\nThis case has been presented here for its rare presentation in an adolescent girl because LH is mostly seen in young females and postpartum period and its unique presentation as an expanding pituitary mass with optic chiasma compression.