Aquagenic keratoderma. Two new case reports and a new hypothesis
A 12-year old girl presented with three months history of burning of palms and loss of skin dermatoglyphics after exposure to water []. Symptoms were temporary; changes faded away within 20 min. The patient did not have concomitant diseases and was not on any medication. Clinical examination revealed hyper-wrinkling of the palms after immersion in water without any other skin and/or mucous changes. Routine laboratory examination was unremarkable.\nTherapy was initiated with 20% alcohol solution of aluminum chloride hexahydrate once daily at night. The treatment resulted in significant clinical improvement with reduction of the frequency and duration of AK episodes.