Granuloma faciale: a rare disease from a dermoscopy perspective
Male patient, 40 years old, referred an erythematous-edematous asymptomatic lesion in\nthe right malar region for 4 years. He denied other skin lesions, systemic symptoms and\ncomorbidities. He was using topical steroids (betamethasone dipropionate 0.05% cream)\nand prednisone 60 mg / day for 2 months. Physical examination showed erythematous\nplaque, infiltrated, on the right malar region, with prominent follicular orifices,\nassuming a "peau d'orange" appearance. ().\nThe dermoscopic examination showed a pink background, with some areas blackened, white\nstriations in different directions and prominent follicular orifices ().\nHistopathological examination showed intense mixed inflammatory infiltrate of\nmicronodular aspect, composed of lymphocytes, histiocytes, neutrophils and numerous\neosinophils. The described infiltration had not reached the subepidermal region (Grenz\nzone) and there was no evidence of vasculitis (). Immunohistochemistry suggested polyclonality (CD3 +, CD4 +, CD8 +, CD30\n+).\nGF was diagnosed based on clinical examination, dermoscopy and histopathological\naspects. Laboratory tests were within normal limits, and ANA (antinuclear factor), VDRL\n(Venereal Disease Research Laboratory) and smear lymph, negatives. Dapsone was\nprescribed 100 mg / day. Intralesional corticosteroid and prednisone were suspended. The\npatient returned after nine months of treatment with partial improvement ().