Two Patients Diagnosed with Juvenile Myoclonic Epilepsy by First-Ever Status Epilepticus in Adult Life
A 52-year-old woman presented with generalized tonic-clonic seizure (GTCS) at the first seizure attack. In general, she was healthy, and only suffered from mild headache in the past few months.\nDuring the night before visiting the ER, she showed inappropriate behavior, confusion, and disorientation. A few hours later, she showed GTCS lasting for 1–2 minutes, and then, remained in a mild confusion state in the ER. There were no abnormal findings on the brain MRI and in the CSF analysis.\nDuring the confusion state, on the EEG, there were repetitive, high voltage generalized polyspikes and waves with flat periods () which subsided after intravenous injection of lorazepam. Detailed history taking revealed previous occasional absence-like episodes and myoclonic jerks. The patient’s younger sister also suffered from epilepsy since childhood.\nThe epileptic discharges were all abolished on the follow-up EEG.\nThe patient was diagnosed as JME and there has been no recurrence of seizures with sodium valproate medication.