Leiomyoma: A rare tumor in the head and neck and oral cavity: Report of 3 cases with review
A 48-year-old male patient was referred to our department with a chief complaint of swelling in relation to right upper molar teeth since 2 months.\nOn examination, a solitary swelling was noted on the right side of the posterior palate associated with right upper second premolar and first molar measuring 1 cm × 1.5 cm. Overlying mucosa was pale pink in color and appeared normal. The swelling was a sessile, firm, dome shaped mass fixed to the underlying tissues [].\nAspiration biopsy was performed, which ruled out a vascular lesion. Radiographic picture showed no changes associated with underlying bone. The lesion was provisionally diagnosed as a minor salivary gland tumour. Excisional biopsy was performed and excised mass was sent for histopathologic examination [].\nThe lesional tissue present in the deeper stroma was well-circumscribed and non-encapsulated and the cells were arranged in a streaming pattern around the blood vessels []. They formed whorls, which were separated by collagen bands. Numerous vascular spaces were seen surrounded by proliferating spindle cells []. The lesional cells were spindle in shape with blunt ended nucleus and had a moderate amount of cytoplasm with indistinct outline. There was no evidence of mitosis or necrosis. Thus, a diagnosis of angioleiomyoma was made.\nNote: Special stains were done using Mallory's Phosphotungstic Acid-Hematoxylin for all the above three cases and the cells exhibited dark blue intracytoplasmic fibrils []. Masson trichrome staining exhibited smooth muscle cells (pink) in longitudinal and transverse sections with intervening collagen fibers (blue) [Figures –].