Generalized eruptive histiocytoma: a rare disease in an elderly patient
A 79-year-old white man from Alagoas presented with a two-month-history of multiple asymptomatic disseminated erythematous papules. The dermatological examination showed erythematous papules, symmetrically distributed and widespread on the tegument, some in clusters, more evident on the dorsal aspect of the trunk and limbs ( and ). The scalp, mucous membranes, palms and soles were spared. The patient had no systemic signs or symptoms, and lesion sensitivity was preserved.\nConsidering the differential diagnosis of syphilis and leprosy, specific laboratory tests were performed and the results were negative. Skin biopsy showed dense mononuclear dermal infiltrate without atypia, occupying the entire dermis, and perivascular lymphocyte clusters on the superficial dermis (). Wade staining was negative. The immunohistochemical examination was positive only for CD68 and negative for CD1a, CD34 and S100 ().\nThe diagnosis of GEH was based on the association of clinical, histopathological and immunohistochemical findings. The lesions regressed spontaneously after two months and he has no history of recurrence to date.