A Case of Cerebral Aneurysmal Subarachnoid Hemorrhage in Fabry's Disease
A 42-year-old woman, who had no previous medical history experienced the sudden onset of severe headache and followed by loss of consciousness. A computed tomography revealed that subarachnoid hemorrhage was located in the basal cistern. Cerebral angiography on the day of admission demonstrated a saccular aneurysm of the right posterior communicating artery (). The aneurysm was treated by an endovascular coil embolization (). Postoperative computed tomography revealed the resolved subarachnoid hemorrhage without posthemorrhagic hydrocephalus and infarction. The patient recovered favorably without any neurological deficit. During her admission, she showed proteinuria in urine analysis. In kidney needle biopsy, the pathologic findings implied nephrosialidosis (mucolipidosis of lysosomal stroage disease) consistent of Fabry's disease (). The patient was transferred to the department of nephrology, where she was treated with a gene therapy and medical management. The patient recovered favorably, discharged without any neurological residual symptom.