Circumscribed palmoplantar hypokeratosis: report of two Brazilian\ncases
Case 1: Female patient, 68 years old, white, had had lesions on the palms for 30 years.\nThere was no history of trauma or local infection. The dermatological exam showed two\nreddish plaques of approximately 5x5mm on the right palm and 5x10mm on the left palm.\nThe lesions were circumscribed, nummular, depressed and located symmetrically over the\nthenar regions ( and ). Her soles were not involved. The general clinical examination\nwas not significant. Direct mycological examination was performed with negative results,\nand histopathological aspects of skin biopsy showed a focus of sharp decrease in the\nstratum corneum thickness, mild acanthosis and no change in the basal layer ().\nThe one year follow-up showed no change of clinical lesions.