Changes in Optical Coherence Tomography Findings in Acute Zonal Occult Outer Retinopathy
A 39-year-old Japanese woman presented with a complaint of photopsias and central scotoma in her right eye. Best corrected visual acuity (BCVA) was 0.7 and 1.2 in her right and left eyes, respectively. Intraocular pressure was 16 mm Hg in each eye. The patient had no specific past medical history. No inflammatory cells were observed in the anterior segment or vitreous of either eye, and there were no specific abnormal findings during a fundus examination (fig. ).\nOCT (RS-3000; Nidek, Japan) showed that while there was attenuation of the IS/OS line throughout the entire region of her right eye and the COST line (fig. ), no specific abnormalities were detected in her left eye (fig. ). mfERG (LE-4100; Tomey, Japan) findings showed markedly decreased amplitudes in the right eye (fig. ) and no abnormalities in the left eye (fig. ). The patient was followed without any treatment. BCVA improved to 0.9 in the right eye and OCT revealed there was no recovery of the IS/OS at the foveal area at 1 month after the initial visit (fig. ). After 2 months, BCVA improved to 1.2 in the right eye and OCT showed a partial restoration of the IS/OS line (fig. ); however, the COST line was still absent, and she had no change in mfERG findings. At 4 months, reappearance of the IS/OS line was detected by OCT (fig. ). However, the COST line was still absent, and she showed no improvement in the mfERG findings. Fluorescein angiography and indocyanine green angiography were not available in this case.