Clinical experiences in fungal keratitis caused by Acremonium
A 75-year old male patient was injured in his left eye with vegetable matter. On slit-lamp examination of the left eye, there was a central white stromal infiltrate with corresponding epithelial defect and endothelial plaque (). Corneal smears showed hyphae. The patient was started on an hourly instillation of topical 0.5% moxifloxacin, 0.15% amphotericin B, 0.2% fluconazole, and oral fluconazole. After 7 days on this therapy, the size of the infiltrate was markedly reduced, and the hypopyon had disappeared. Corneal cultures were subsequently positive for Acremonium. The final BCVA was 0.5, and there was no recurrence in the following 4 months ().