Fine needle aspiration cytology of pseudosarcomatous reactive lesions of soft tissues: A report of two cases
A 65-year-old man presented with a hard mass measuring 4 × 3 cm in the supraclavicular region. Clinical diagnosis was secondaries in the lymph node. FNAC was performed. The smears were moderately cellular and showed proliferative spindle cells among the skeletal muscle fibers. Good number of uni and multinucleated cells having enlarged and atypical nuclei were seen. Giant cells were conspicuous [Figure and ]. A diagnosis of metastatic tumor was made. The patient underwent various tests, but no primary was detected. The mass was excised. Grossly, the mass was grey-white and measured 3×2 cm. On histopathology, there were skeletal muscle fibers and fibro-collagenous tissue with chronic inflammatory cells, proliferating fibroblasts and giant cells. Giant cells had abundant dense eosinophilic cytoplasm and vesicular nuclei with prominent nucleoli. The features were consistent with a diagnosis of proliferative myositis.