Benign fibroushistiocytoma of the gingiva
A 23-year-old male patient reported with a chief complaint of a growth on the gums of the lower front teeth region for past 1 month. The growth was small when he noticed it and gradually increased in size. Clinical examination revealed two small growths, on both the buccal and lingual aspect of the interdental papillae of 32 and 33. The surface of these growths appeared reddish pink in color measuring around 1 cm × 1 cm in size. On palpation, the growth was firm in consistency and non-tender [Figures and ].\nAn excisional biopsy was carried out and both the buccal and lingual growth were submitted separately for histopathological investigations. The section made from the buccal growth showed a connective tissue mass devoid of epithelium. The connective tissue showed budding capillaries toward the center with dense infiltrate of chronic inflammatory cells. The periphery of the mass appeared to be covered by a pseudomembranous layer.\nThe lingual growth showed a highly cellular connective tissue mass covered by a proliferating epithelium. The lesional cells were plump spindle shaped cells, which in certain areas showed the crisscross pattern or storiform arrangement. The connective tissue had also shown numerous round histiocytic cells and blood vessels.\nThe sections were sent for immunohistochemistry to detect the expression of Vimentin, smooth muscle actin (SMA), desmin, S-100 protein and CD34. The sections showed strong positivity for vimentin and negative expression for vascular, muscular or neural markers [].\nBased on the histopathological features and immunohistochemistry findings, a diagnosis of benign fibroushistiocytoma was given.