Disseminated metastatic penile squamous cell carcinoma detected by fluorodeoxyglucose PET/computerized tomography
We report a case of a 57-year-old male demonstrated inguinal metastases with biopsy then underwent amputation and recognized histopathological grade 2 (moderately differentiated) penile SCC. The patient was referred to our PET/CT department to search for possible further metastatic disease. Following 10 h fasting (serum glucose level 126 mg/dl), the patient was injected with 14.5 mCi F-18 of fluorodeoxyglucose(FDG) intravenously. After 1 h waiting period, whole-body images were obtained on the Siemens HI-REZ PET/CT System. Fused images of metabolic (PET) and anatomic (CT) information were reviewed. PET/CT study showed that intense accumulation of FDG on inguinal lymph nodes. Additionally, increased FDG uptake was detected on multiple lymphadenomegalies in abdomen-pelvis and the left-inferior jugular region, the left supraclavicular fossa and the mediastinal lymph nodes [Figures and ]. Also, PET images demonstrated a few uptakes in the left axilla and left parasternal lymph nodes. The lung parenchyma, liver and skeletal system demonstrated a physiological distribution of the tracer. Histopathological results showed primary penile SCC carcinoma [] and metastatic inguinal lymph nodes [].