Schwannoma of floor of the mouth
A 28-year-old male patient presented with a complaint of enlarging swelling of 1 month duration in the right anterior floor of the mouth which was otherwise asymtomatic. On intra-oral examination, a 4 × 3 cm swelling in the right anterior floor of the mouth, with smooth surface, well-defined border, covered with normal appearing mucosa, was noted. On palpation, it was firm and tender. Computed tomography (CT) scans (axial view) showed a well-defined heterodense mass measuring 3.5 × 2.5 × 2.5 cm, with specks of calcification in the right sublingual region. There was a hypodense rim around the swelling causing smooth erosion of the adjacent mandible. No evidence of cortical irregularity or periosteal reaction was found. Furthermore, multiple enlarged, submental and bilateral submandibular lymph nodes were seen [].\nBased on the clinical findings, the CT scan features and anatomical location a provisional diagnosis of salivary gland tumor involving sublingual gland was given. The patient underwent surgical excision of the mass under general anesthesia; the post-surgical course was uneventful.\nMacroscopically, the resected mass was encapsulated, greyish-white in color, measuring 4 × 4 × 3 cm. It was oval, smooth and firm in consistency []. Microscopic examination revealed a well encapsulated tumor exhibiting areas of organized spindle-shaped cells in palisading arrangement around acellular, eosinophilic areas forming Verocay bodies giving Antoni type ‘A’ pattern. Other areas with Antoni type ‘B’ pattern exhibited less cellularity, less organized cells, which were plump, spindle-shaped and were generally seen adjacent to densely vascular areas []. Immunohistochemical investigation of the tumor cells showed diffuse, strongly positive staining for S-100 protein []. These findings were compatible with the diagnosis of Schwannoma.