Harlequin syndrome in childhood - Case report
A nine-year-old female patient reported unilateral flushing associated with ipsilateral\nsweating when submitted to prolonged physical exercise. It started at the age of six,\nbeing unaltered since then. The opposite side of the face remains pale and anhidrotic.\nThese skin changes could be reproduced during her examination, 30 minutes after\nexercising, with flushing and sweating ().\nIn contrast to the patient's beliefs, the affected side is not the one with normal\nvascular and sweat response, but the pale and anhidrotic side. Her medical history had\nno other diseases or accidents. No birth problems (such as forceps usage) were\nidentified. A neurological and ophthalmological evaluation made by a neuropediatrician\nand an ophthalmologist was normal (with no need for additional tests).