Solitary Rectal Ulcer Syndrome in Children: A Report of Six Cases
A 14-year-old boy admitted with massive rectal bleeding. He had had abdominal pain and bloody diarrhea (10 to 12 episodes daily) during the last 3 months. His physical examination was normal except for pallor. Initial laboratory examinations revealed only anemia (Hb, 10 g/L). Colonoscopy was performed and revealed a lesion located circumferentially at a mean distance of 5 cm from the anal verge. Histopathological examination, including hyperplasia of lamina propria, mild crypt distortion confirmed the diagnosis of SRUS (). Combined oral and enema treatment with mesalazin (Salofalk, twice daily dosing) was initiated. Rectal steroid and rectal sucralfate (3×5 cc/day) was added. He responded well to the treatment and rectal steroid discontinued after 1 month. The rectal bleeding ceased (once every other day). Stool became soft and frequency decreased to two to three times a day. He is currently being followed with ongoing therapy (rectal sucralfate 2×5 cc/day) for SRUS.