Isolated primary craniosynostosis in an adult: Imaging findings of a case
A 31-year-old female was brought with a history of severe mental retardation since birth. She had a history of global developmental delay also. Both the parents were normal with no consanguinity. On physical examination, she had a peculiar face with hypertelorism and deformed calvarium. There was no mandibular hypoplasia or midfacial deformity. No microcephaly or abnormal nasal configuration was seen []. Her hands and feet were normal with no syndactyly. X-ray of the skull [Figure and ] showed prominent convolutional markings on the calvarium with complete closure of all calvarial sutures. No harlequin eyes were seen. Plain computed tomography (CT) confirmed the X-ray findings. All the sutures were closed and showed bone bridging and heaping. Inner table of skull showed extensive convolutional markings [Figure and ]. The brain parenchyma was normal with no atrophy. Corpus callosum, both leaves of the septum pellucidum, and posterior fossa structures were well seen. However, the subarachnoid space and cisterns showed effacement. The ventricular system was normal []. The paranasal sinuses were hypoplastic. All these imaging findings along with the supporting history were consistent with primary isolated craniosynostosis.\nThe uniqueness of our case lies in the presentation of imaging findings of the patient with primary craniosynostosis who survived into adulthood without undergoing any corrective surgical procedure, whereas the literature describes such findings in infants and children only.