Efficacy of reduced-fluence photodynamic therapy for serous retinal pigment epithelial detachment with choroidal hyperpermeability
The patient was a 42-year-old man. He had been attending hospital for 4 months, with the principal complaint of distorted vision in the right eye. On initial examination, logMAR BCVA of the right eye was −0.2. The images of FA, ICGA, and OCT were described in . No serous retinal detachment was evident on OCT images, which showed serous PED of one-fifth of the disc diameter at the subfovea, and continuity of the IS/OS line was unclear. FA showed hyperfluorescence in the same location as the PED, and ICGA revealed hyperfluorescence of the PED from the mid-phase to the late-phase and weak hyperfluorescence around the PED due to hyperpermeability of the choroidal vessels, resulting in a diagnosis of ISPED. Because the PED had not improved, RFPDT (spot size: 3,300 μm) was performed 6 months after onset. The PED was seen to have completely disappeared 1 month after RFPDT. Continuity of the IS/OS line was restored on OCT images, and logMAR BCVA was maintained, with symptomatic improvement of distorted vision. Visual acuity was maintained at 6 months posttreatment, with no recurrence of PED. No adverse events were seen in this case during follow-up after RFPDT.