Mucoepidermoid Lung Carcinoma in Child
A 6-year-old male child was presented with fever, cough, hemoptysis and wheezing since1 month. Chest X-ray showed features suggestive of foreign body with post-obstructive pneumonia-left lung and was treated for the same with medication without much improvement. Family history and developmental history was unremarkable. Routine hematological, biochemical and microbiological investigations were unremarkable. Subsequently CT scan chest was carried out, which showed oval mass with speculated margin in right hilar region [, shown in arrows] with distal segmental atelectasis. Bronchoscopy showed small growth with nodularity in the apical segmental bronchus of the right lower lobe with mucosal erosion and hence carried out bronchoalveolar lavage showed few atypical squamous cells. Post-bronchoscopy sputum was unremarkable. CT abdomen and pelvis showed no evidence of metastatic deposits. Hence, patient underwent left lower lobectomy. The right lower lobectomy showed a grey white oval mass with solid and cystic areas in the right hilar region with extension in to the lung parenchyma []. Histology of the tumor showed mixed solid and cystic areas with sheets of epidermoid cells and mucus-filled cysts of irregular size [Figure and ]. Areas of solid growth were composed of squamoid and intermediate cells [ and ]. Epidermoid cells showed inter cellular bridges []. Cysts were lined by columnar cells with mucin-rich cytoplasm. These cells were positive for periodic acid-Schiff stain []. Hence, the final diagnosis of mucoepidermoid carcinoma-intermediate grade of right lower lobe was made. Lymph-vascular invasion and lymph node metastasis were negative. The post-operative course was good. Since the tumor was low-grade, no adjuvant treatment was administered. Patient had no signs of tumor recurrence for 1 year, to date, since the resection of the tumor.