Xanthoma of the urinary bladder – A rare entity
A 46-year-old woman was seen with urgency and incontinence for 10 years. She had undergone Caesarean section on two occasions, the last one being 14 years earlier. Cystoscopy was performed as she had microhematuria. A yellowish slightly elevated nodule 5 mm × 5 mm was found on the dome of the bladder. She was not diabetic. Biopsy showed sheets of foam cells in the lamina propria of the bladder mucosa []. There was neither any inflammation nor evidence of malignancy. The foam cells were faintly positive for PAS and negative for PASD. Von Kossa and iron stains were negative. On immunohistochemistry, the cells were negative for Cytokeratin and positive for CD68 [] confirming their histiocyte/macrophage origin.