Recurrent Stereotyped Episodes in Cerebral Amyloid Angiopathy: Response to Migraine Prophylaxis in Two Patients
An 81-year-old woman presented with a 2-month history of recurrent 5-min episodes of left hand and arm numbness and leg weakness, later evolving to attacks including speech. Exam was normal. MRI showed areas of subcortical hemosiderin on GRE. One month later, she developed sudden cognitive impairment. MRI showed a right temporal lobe intraparenchymal hemorrhage and edematous T2 lesions in both occipital lobes. Transient left-sided sensory symptoms continued, less frequently, for 2 months and then stopped completely. They have not recurred for 24 months.