Neutralizing antibodies to botulinum neurotoxin type A in aesthetic medicine: five case reports
The final case study involved a 38-year-old European male. His treatment began in 2010 when he received 120 U of abobotulinumtoxinA (Dysport®) over three injection points each in the frontalis, corrugator, and procerus (). The initial duration of effect was 6 months. In 2011, he received 200 U in the same injection points with a duration of effect of only 2 months. His final treatment, in 2012, with 250 U of Dysport® produced no effect. Results of antibody titers were high positive (++).