Isolated central venous pressure elevation caused by hematoma formation compressing the superior vena cava following a Bentall operation: a case report
A 70-year-old male patient underwent a Bentall operation due to annulo-aortic ectasia, which was combined with severe aortic valvular insufficiency. The patient's height and weight were 165 cm and 50.9 kg, respectively and he had no co-morbid diseases except for hypertension, which was treated with a calcium channel blocker and an angiotensin converting enzyme inhibitor. The patient had a normal sinus rhythm, and the preoperative transthoracic echocardiography (TTE) revealed a left ventricular ejection fraction of 58% with no other intracardiac pathologies. Coronary angiography also revealed normal coronary arteries. After anesthetic induction, the patient's hemodynamic variables were as follows; systemic blood pressure 113/38 mmHg, heart rate 83 beats/min, central venous pressure 9 mmHg, and pulmonary arterial pressure 33/15 mmHg. A Bentall procedure was uneventfully performed and the patient was weaned off from cardiopulmonary bypass (CPB) without difficulty. The total aorta cross clamp time was 95 minutes and the total CPB time was 115 minutes. Before leaving the operating room, there was no evidence of fluid collection in the pericardial and pleural space in the transesophageal echocardiography (TEE), with the estimated left ventricular ejection fraction being 50%. Receiving norepinephrine 0.08 µg/kg/min, milrinone 0.25 µg/kg/min, and vasopressin 0.8 IU/hr, the hemodynamic parameters were as follows: heart rate of 80 beats/min, blood pressure of 87/48 mmHg, CVP of 10 mmHg, pulmonary arterial pressure of 24/15 mmHg, cardiac index of 3.4 L/min/m2, mixed venous oxygen saturation of 90%, right ventricular ejection fraction of 39%, and right ventricular end diastolic volume index of 141 mm/m2. The patient was transported to the intensive care unit (ICU) without any further events. In the ICU, as in the operating room, the patient's lungs were ventilated with a tidal volume of 500 ml at a rate of 12 breaths/min, with a fraction of inspired oxygen of 40% medical air, along with 5 cmH2O of positive end-expiratory pressure. The corresponding peak airway pressure and plateau airway pressure were 19 cmH2O and 17 cmH2O, respectively. The arterial blood gas analysis revealed pH 7.419, PaO2 123.8 mmHg, and PaCO2 34.7 mmHg. Over a period of 30 minutes in the ICU, the CVP increased from 10 to 23 mmHg, and the pulmonary artery diastolic pressure increased from 14 to 17 mmHg. The blood pressure was 90/49 mmHg, and the cardiac index was maintained at 2.7 L/m/m2 without increasing doses of norepinephrine, milrinone, and vasopressin. The electrocardiogram (ECG) revealed nonspecific ST wave changes without any changes in the height of the QRS waves, and the chest X-ray showed partial atelectasis of the right lung and moderate cardiomegaly. The patient's respiratory mechanics and follow-up arterial blood gas analysis showed no significant changes. His hemoglobin was 8.7 g/dl which is near the former value measured in the operating room of 9.0 g/dl. The platelet count was 82 × 109/L and the International Normalized Ratio of the prothrombin time was slightly elevated at 1.54. During the first 15 minutes after the surgery, 100 ml of blood were drained from his mediastinal and chest drains. Because, there was no further chest tube drainage, 100 ml of 6% hydroxyethyl starch 130/0.4 solution was infused without any transfusions.\nA TEE examination was immediately performed to confirm the cause of the CVP elevation, which revealed minimal pericardial fluid collection and preserved biventricular function in the midesophageal four-chamber view and the transgastric short axis view. The midesophageal bicaval view showed the right atrium (RA) being pushed anteriorly and laterally by a large mass measuring 6.06 cm × 8.78 cm (). The mass contained echogenic materials with some echo-free areas, which is consistent with hematoma, and as a result the SVC was almost completely obliterated by it. In the midesophageal aortic valve long axis view, the hematoma occupied the transverse sinus as well (). The patient was immediately transferred to the operating room for re-exploration. A loculated hematoma around the valved graft was found to compress the entire SVC and extended to the RA. After evacuation of the hematoma, the CVP decreased immediately from 23 to 11 mmHg. The cardiac index and the blood pressure remained stable despite the discontinuation of the vasopressor and inotropic agents. However, the patient's postoperative course deteriorated, with the development of acute renal failure and adult respiratory distress syndrome, which resulted in the prolongation of ICU stay. The patient was then transferred to the general ward at postoperative day (POD) 52 for rehabilitation, and discharged at POD 109.