Polymorphic Eruption of Pregnancy Presented with Targetoid Lesions: A Report of Two Cases
A 26-year-old Thai female G1P0 at 39+4 weeks of gestation presented with a 1-week history of severely pruritic erythematous papules and plaques beginning on the abdomen and subsequently involving all extremities. Neither systemic symptoms nor fetal distress was observed. She had been receiving standard antenatal care since she was 13 weeks pregnant. Her medication was only ferli-6 and calcium carbonate. Physical examination showed multiple, discrete, ill-defined, erythematous papules and confluent plaques with central dusky red areas (targetoid lesions) on the abdomen, back, and all extremities (fig. ). Palms, soles, and mucosa were not affected. An indirect immunofluorescent study was done to exclude pemphigoid gestationis, and the result was negative. Systemic corticosteroids were initially given. Then, topical corticosteroids together with oral antihistamines were prescribed instead. Her symptoms improved over time and she delivered a healthy, term, female infant.