Endometrial Osseous Metaplasia: Case Report with Literature Review
A 28-year-old woman presented with history of menorrhagia. She was married for 4 years and she gave a history of one full-term vaginal delivery and a miscarriage subsequent to which she underwent dilatation and curettage at 13 weeks gestation 6 months ago. Menstrual history was normal before the event. Her general examination and bimanual exploration were normal. Her routine haematological parameters were normal and no abnormality was detected.\nHistopathological evaluation of endometrial curettage material was carried out. On gross examination, multiple irregular, tiny, hemorrhagic tissue bits altogether weighing 25 g. Microscopic examination of H and E, stained sections showed mature bony trabeculae with non-hematopoietic bone marrow [], []. The surrounding endometrial tissue revealed tubular endometrial glands with scanty stroma and the mild stroma infiltration by chronic inflammatory cells. There is no evidence of granulomas and the metaplastic nature of this condition is proved morphologically by its continuity with stromal cells.\nThe patient had no signs or laboratory findings suggesting a calcium metabolism disorder.\nA histopathological diagnosis of endometrial osseous metaplasia was given.