Circumscribed palmoplantar hypokeratosis: report of two Brazilian\ncases
Case 2: Female patient, 84 years old, white, had had a single lesion on the left palm\nfor over 24 years. The patient had no history of trauma or local infection. The physical\nexamination revealed a reddish, nummular, depressed and circumscribed patch, about 5 mm\nin diameter, located over the thenar eminence of the left palm ( and ). There were\nno lesions on contralateral palm or on soles.\nDirect mycological examination was performed with negative results. Histologically, it\nshowed an abrupt, well-demarcated decrease in the thickness of the stratum corneum and a\ndiminished granular layer ().