Case Reports of Incontinentia Pigmenti in Males
A 20-days-old male child, second in order, born to non-consanguineous parents, with an uneventful normal vaginal delivery, was brought with the complaints of vesiculobullous eruptions on both lower limbs [Figures ] and ] and right arm since birth. The other sibling was a male child who expired at 7 months of gestational age due to hydrops fetalis. On examination, the child had vesiculo-bullous lesions on both lower limbs. Hair and nails were normal.\nThe infectious causes were excluded (Tzanck test showed no giant cells, and test for antibodies for HSV, VZV was negative). Systemic examination including that of eyes, CNS, and skeletal system revealed nothing abnormal. Routine blood, urine, and stool examinations did not show any abnormality, except for raised eosinophils on differential leukocyte count. VDRL of mother and the child was non-reactive, and a skin biopsy was performed, which revealed spongiotic intra-epidermal vesicles with a rich eosinophil infiltrate [].