Aggressive Curettage-Cryosurgery for Human Papillomavirus-16 Associated Subungual Squamous Cell Carcinoma In Situ
The first patient was a 58-year-old female with a subungual BD on a finger. She had previously been described as having a patient-specific HPV-16 strain in archival sample from intraepithelial neoplasia grade II on the portio of the uterine cervix in 1970 and subsequently in a subungual BD of the left ringfinger.[]\nIn 1995 an incomplete surgical excision of the subungual tumour was performed and therefore the surgeon suggested extirpation of the terminal phalanx. However, the patient, as being a pianist, wanted to try another form of treatment. In 1996 CC was carried out. After avulsion of the nail the tumour was found to cover most of the nail-bed. The patient had slight pain during the first few days after treatment but no analgesics were needed. Healing by secondary intention was without any complications. The final result was good with a well-functioning finger and with no recurrence after more than 5 years [Figures –].