Striatal Dopaminergic Functioning in Patients with Sporadic and Hereditary Spastic Paraplegias with Parkinsonism
This 44-yr-old female presented with a 1-yr history of progressive weakness in the lower limbs. Her gait was spastic and ataxic in nature. To ascertain whether she had a genetic disease, she was evaluated for SCA types 1, 2, 3, 5, 7, and 8 and all were normal. She presented with normal cranial nerves, and spasticity muscular strength grade 4 in the lower limbs. Her gait became aggravated, and she is now at the age of 49 yr wheelchair-bound.