One day wonder: Fast resolution of macular edema following intravitreal ranibizumab in retinal venous occlusions
A 60-year-old hypertensive man presented with decreased vision in the left eye since 6 months. Patient had been diagnosed with ischemic CRVO and secondary glaucoma in the left eye. He had undergone trabeculectomy in the left eye and was previously treated with intravitreal bevacizumab followed by intravitreal Ozurdex for persistent macular edema. Anterior segment evaluation of left eye showed well-formed bleb, no neovascularisation in iris or angle. Intra-ocular pressure was within normal limits. Fundus evaluation of the left eye was suggestive of old CRVO with diffuse macular edema []. Fundus fluorescein angiography (FFA) showed leakage within the foveal avascular zone (FAZ) in the late phase, there was no leakage related to neovascularization []. 3D spectral domain optical coherence tomography (OCT) (Optovue) showed gross cystoid macular edema [].\nPatient was treated with intravitreal ranibizumab (0.5 mg) in the left eye and 3D OCT was repeated the next day. A significant reduction in macular edema was demonstrated on OCT with reduction in central foveal thickness [].