Recurrent Gingival Swelling in Pregnant Women
A thirty year old pregnant (third trimester) female reported to the department, with painless mobile nodular swelling in lower left buccal and lingual area []. There was slight bleeding on brushing and difficulty in speaking. After clinical examination a solitary exophytic growth measuring 1 cm × 2 cm × 1.5 cm was present on mandibular buccal and lingual gingiva in relation to 33 since last one month. Growth was soft in consistency and non tender on palpation. There was no associated regional lymphadenopathy. Radiographic findings showed no overt alveolar bone destruction in the area of soft tissue enlargement. Blood investigation revealed increase in the level of ESR. Blood count did not show eosinophilia. The growth was surgically excised and send for histological and immunofluorescence examination. After three months patient reported back with recurrent gingival swelling in left mandibular canine. The gingiva was soft and tender. This time swelling was decreased in size, and surgically removed.\nThe exophytic overgrowth was excisionally removed and send for histiological examination. The biopsy sections revealed focally ulcerated squamous epithelium. Underlying proliferation of variably sized blood vessel was seen which were lined by plump endothelial cells. Some markedly dilated spaces contained thrombi. The endothelial cells showed round nuclei and eosinophilic cytoplasm. A dense cellular inflammatory infiltrate, mainly lymphocytes, plasma cells and eosinophils and mast cells were found, surroundings the vessels. There were no signs of mitosis and atypical cells [].\nIt was done using the CD31 marker and revealed the positivity of the cells for CD31 proving that the epithelioid cells seen are vascular in origin.