Epidermolysis bullosa pruriginosa: A report of two cases
A 34-year-old female patient came to the outpatient department with complaints of skin lesion over both the lower limbs associated with intense itching was noted since 15 years. No seasonal variation in lesions. There were no lesions in the oral cavity. None of the family members had similar lesions. The patient was non-diabetic and normotensive. Cutaneous examination revealed lichenoid papules over both shins extending on to the knee [Figures and ]. Papules were non tender associated with mild scaling. There was no associated nail or mucosal involvement. Lab investigations were normal. Skin biopsy showed subepidermal bulla filled with fibrin and RBCs. Dermis showed perivascular mixed inflammatory cell infiltrate and cyst lined by stratified squamous epithelium [Figures and ]. Direct immunofluorescence was negative.\nThe patient was started on topical steroids with systemic antihistamines with minimal response after one month.