Aromatase inhibitors in male sex
A 27-year-old male was referred for poor semen quality. His total functional sperm fraction (TFSF), denoted by sperm count (×106) by normal morphology (%) by normal motility (%), was 70 × 106/ml × 30% × 30% =6.3.\nT - 257.9 ng/dl; E2 - 35.8 pg/ml; T/E2 = 7.2:1.\nHe was prescribed letrozole - 2.5 mg - 2 times/week.\nAfter 1 month of therapy: T - 754.9 ng/dl; E2 - 28.5 pg/ml; T/E2 = 26.5:1.\nThere was 200% increase in T and 20% decrease in E2.\nTFSF - 80 × 106 × 70% × 30% =16.8.