Angioleiomyoma of the Forearm
A 37-years-old female presented with a slowly enlarging mass in the right forearm since two years. She occasionally experienced pain and tenderness over the lesion. There was no history of trauma, and the patient was otherwise healthy.\nOn physical examination, an ovoid swelling measuring 1.5 × 1.5 × 1 cm was present on the right forearm. It was subcutaneous in plane and free from underlying bone. The lesion was smooth and firm. There were no skin changes and no signs of infection. There were no other masses and lymphadenopathy.\nAn excisional biopsy was done and sent for histopathological examination. The specimen, measuring 1.5 × 1.5 × 1 cm, was well encapsulated. On cut section it was gray white and solid. On examining the histopathological sections, many slits like vessels interspersed among spindled shaped tumor cells arranged in whorls and interlacing fascicles were revealed. The vessels were surrounded by an inner layer of muscle arranged circumferentially and outer layer blending with the less ordered tumor cells []. Islands showing lipometaplasia were also observed among tumor cells []. There was no evidence of nuclear atypia, mitosis, or necrosis. On immunohistochemistry, these tumor cells were diffusely positivity for Smooth Muscle Actin (SMA) [] and endothelial cells lining the vascular spaces were positive for CD34 []. In view of the above histopathological and immunohistochemical findings, a diagnosis of solid variant of angioleiomyoma was made.\nPost-operative period was uneventful with no evidence of recurrence.