Congenital multiple clustered dermatofibroma and multiple eruptive\ndermatofibromas - unusual presentations of a common entity
A 12-year-old girl presented with a congenital asymptomatic cutaneous lesion on the\nright thigh. According to the patient, the lesion had been stable for years, but had\ngrown in the previous year and developed new papular areas. She was otherwise healthy\nand was on no regular medication. Physical examination revealed multiple firm\nred-to-brown papules measuring 5-8 mm in diameter, clustered on the lateral aspect of\nthe right thigh, some coalescing to form one large plaque. The lesions progressed to\nthe posterior aspect of the thigh in a linear arrangement (). A cutaneous biopsy was performed and histopathological\nexamination revealed a hyperplastic epidermis with hyperpigmentation of the basal\nlayer and a dermal proliferation of interlacing fascicles of spindle cells that\ndissociated the collagen ( and ). Immunohistochemistry tests were positive for\nvimentin and negative for α-actin, desmin and CD34. The diagnosis of congenital\nmultiple clustered dermatofibroma was made, and a conservative attitude was adopted,\nkeeping the patient under surveillance.