Chromonychia Secondary to Chemotherapy
A 25-year-old male patient was admitted to the hospital's hematology ward with the diagnosis of acute lymphocytic leukemia. He was being treated with the hyper-CVAD chemotherapy regimen. The hyper-CVAD regimen delivers a combination of drugs in 2 cycles (cyclophosphamide, vincristine, doxorubicin and dexamethasone in cycle A, methotrexate and cytarabine in cycle B), split into smaller doses and administered at more frequent intervals in order to minimize side effects.\nDuring hospitalization, a dermatology assessment was requested. The dermatological examination showed nail injury characterized by transverse, brown-gray hyperpigmentation affecting the proximal half of the nail plate, with a brown band delimiting the healthy nail plate on all fingers (fig. , fig. , fig. ).