Linear IgA bullous dermatosis: report of an exuberant case
We report the case of a ten-month old white male patient from Guarulhos presenting with\nisolated and grouped tense serum-filled vesicles and bullae on healthy skin or on an\nerythematous base, mostly in a rosette pattern ( and ). The patient did not present\nmucosal lesions or fever, and there was no impairment of the patient's general\ncondition. There was intense pruritus. His complete blood count was normal. We raised a\nsuspicion of linear IgA dermatosis and of erythema multiforme. An anatomopathological\nexamination of a bullous lesion showed subepidermal cleavage with neutrophilic\ninflammatory infiltrate ( and ). Direct immunofluorescence (DIF) of perilesional\nskin showed intense linear deposition of IgA at the BMZ (). As we awaited the results of the anatomopathological examination,\nDIF, and of the glucose-6-phosphate dehydrogenase test, we initiated treatment with\nprednisolone 1mg/kg and observed partial improvement of the patient's condition. After\nconfirming the diagnosis of linear IgA dermatosis and detecting normal levels of glucose\n6-phosphate dehydrogenase, we added dapsone 2mg/kg and maintained the oral\ncorticosteroid therapy, with the patient achieving complete remission ().