Two Patients Diagnosed with Juvenile Myoclonic Epilepsy by First-Ever Status Epilepticus in Adult Life
A woman, aged 39 visited the ER with transient loss of consciousness (LOC). W Anamnesis showed that, when she was 27 years old, during excessive working at night, she experienced one episode of LOC without convulsions.\nBoth the brain MRI scan and the EEG performed at that time were normal. Recently, she felt exhausted because of her night job. In the ER, she was alert and could follow all commands, but showed mild confusion. Focal neurological signs were not observed, and brain imaging was normal. Generalized polyspikes and slow waves repetitively occurred on the EEG ().\nThe pathologic waves disappeared after IV injection of lorazepam.\nThe EEG recorded on the following day showed normal background activity and decreased slow wave activity.\nWith careful history taking, we found out that she also experienced a myoclonic jerk soon after awakening. She was diagnosed as JME, and no further seizures occurred after sodium valproate administration.\nDue to the occurrence of hand tremor, the sodium valproate treatment was changed to lamotrigine during the follow-up period.