Solitary Rectal Ulcer Syndrome in Children: A Report of Six Cases
A 10-year-old boy was referred to our pediatric gastroenterology unit with rectal bleeding. He had had episodes of diarrhea, sometimes bloody, during 10 years. Diarrhea had worsened (bloody and increased in frequency) over the 3 months before admission. His physical examination was unremarkable except for rectal prolapse. He had normal growth and had any evidence of bleeding diathesis, significant anemia, bacterial or parasitic infection, or any other systemic diseases. The laboratory examinations including complete blood count, stool examination for parasites and ova, Clostridium difficile toxin and coagulation profile were normal.\nColonoscopy showed an ulcer 2×2.5 cm in diameter located at 6 o'clock in the rectum. Histopathological examination revealed fibromuscular hyperplasia of the lamina propria. The treatment with mesalazin (5-aminosalicylate [5-ASA]) enema was initiated. The treatment was continued with oral sucralfate for 1 year. He is currently being followed with no treatment and further complaints.