Development of acute dystonia in three brothers due to metoclopramide
A day before being applied to us (Istinye Public Hospital, Istanbul, Turkey, 2008), the patient (6-year-old male) with his two brothers had been taken to a physician with complaints of nausea and abdominal pain. Five milligram dose of metoclopramide had been prescribed to the patient. After receiving the first dose of medication, the contraction and retention of neck, contractions of chin and arms occurred within half an hour in the patient who used metoclopramide. The patients were brought to our clinic. The patient's conscious was clear, but he was agitated and restless. Pulse was 102/min; blood pressure was 85/45 mmHg. Respiratory rate was 27/min as normal. There were speech dysfunction, trismus, and dystonic movements of sleeves. Involuntary movements gradually increased and opistotonus developed. Results of complete blood count (CBC), liver and kidney function tests and electrolytes were within normal values.