Primary cutaneous centrofollicular lymphoma with a good response to\nradiotherapy
A 45 year-old white male, previously healthy, presented infiltrated plaques and\ncoalescent nodules on the left parietal region one year ago. He reported history of\nlocal trauma six months before the onset of the lesion. He denied local or systemic\nsymptomatology (fever, night sweat or weight loss). On the dermatological exam were\nfound plaques and erythematous nodules of hard consistency, measuring about 8x4cm (). Palpable lymphadenopathy was absent. The\nhistopathological exam demonstrated a large diffuse dermal infiltrate that spared the\nepidermis, with a partial follicular component (). The infiltrate was composed of a population of central follicle cells,\npredominantly with multilobed nuclei, associated with large centroblasts and mixed\ncentrocytes and surrounded by a great quantity of small reactive T lymphocytes ( and ).\nImmunohistochemistry was positive for CD5 and CD20 and negative for CD30. After the\ncentrofollicular lymphoma diagnosis, the patient was referred for hematologic evaluation\nfor research on systemic disease, which was negative; the classification was TNM TxN0M0.\nHe was submitted to radiotherapy with 3,060 cGy in 17 fractions on the scalp lesion,\nwith the 9 MeV direct electronic fields technique for 25 days, with good local response.