Locally advanced salivary duct carcinoma of the parotid gland
A 42-year old female had presented to the department with a lump over the right preauricular region since 3 months. Physical examination showed a 5×4 cm hard lump in the right preauricular region. She had no cervical lymphadenopathy nor any clinical signs of facial nerve palsy. Computed Tomography revealed a lump involving the superficial lobe of right parotid gland with no adjacent structures being involved. She underwent facial nerve preserving radical parotidectomy [] with supraomohyoid neck dissection. Histopathology was suggestive of SDC with no nodal metastases. Histopathologically, there was a striking resemblance to ductal carcinoma of the breast with central comedo necrosis and some areas of sarcomatoid morphology. Immunohistochemistry was positive for cytokeratin and negative for SMA, desmin and myogenin in both the areas []. Patient received 60 grays of EBRT and is on regular follow-up. She had no signs of recurrence since seven months of surgery.