Idiopathic Calcinosis Cutis of the Vulva
The patient was a 42-year-old female with two children. On physical examination, there were firm, non-tender, pedunculated nodules measuring approximately 1 cm × 6 cm alongside both vulva without any skin ulceration. It had slowly grown in size during the last 5 years and then remained static. The laboratory investigations revealed within normal serum calcium levels of 9.5 mmol/dL, magnesium levels of 2.4 mg/dL and phosphorus levels of 2.9 mmol/dL. Complete hemogram showed following results; Hb 13.5 g/dL, WBC 5.2 10 3/mL, PLT 270 10 3/mL, and sedimentation rate 25 mm. Blood sugar, uric acid, electrolyte, and liver function and kidney function tests, and routine urine examination were normal. Anti- nuclear cytoplasmic antibodies, serum C3, C4, and CH50 levels, and rheumatoid arthritis test were within normal limits. C-reactive protien (CRP) and antistreptolysine O (ASO) levels were 0.6 mg/dL and 221, respectively. Parathormone level was 63.7 pg/mL. The enyzme linked isosorbent assay (ELISA) tests for anti-human immune deficiency viruse (HIV), anti-hepatit C virıse (HCV), and hepatit B surface antigen (HBSAG) were negative.\nIt caused discomfort during intercourse as the solid nodular masses mobile. The masses were excised under general anesthesia and there was no recurrence at 1-year follow-up [Figures and ]. Skin biopsy specimen demonstrated dermal calcification with a diagnosis of idiopathic calcification [Figures and ]. Any special staining except H and E, was not applied.