Adenoid Cystic Carcinoma of the Breast: A Case Series of Six Patients and Literature Review
A 70-year-old female had a mass in her left breast, which was detected on a routine screening mammogram. Mammography and breast ultrasonography (US) showed an irregular mass measuring 2.4×1.4 cm with a spiculated margin in the upper inner quadrant. Breast magnetic resonance imaging (MRI) showed an irregular enhancing mass in the left breast. Results of a subsequent diagnostic core biopsy indicated an infiltrative ductal carcinoma. The patient underwent quadrantectomy with sentinel lymph node biopsy (SLNB). The tumor was found to be an ACC measuring 2.0×1.9×1.5 cm (nuclear grade, 2), and the sentinel lymph node was negative for metastasis (pT2N0M0). Immunohistochemistry (IHC) of the tumor was negative for estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) expression. The patient did not receive adjuvant radiotherapy or chemotherapy. The patient has been free of recurrence during 28 months of follow-up.