That dyspepsia in the young could be cancer
A 38-year-old female primary school teacher who presented in August 2012 with a 12-month history of recurrent epigastric pain, which responded initially to anti-ulcer medications, but later developed anorexia, early satiety, weight loss and vomiting. She had no history of dysphagia or odynophagia. She also had no history of intake of smoked foods, alcohol consumption, cigarette smoking or family history of GI malignancy. Physical examination was unremarkable except for palor and epigastric tenderness. Upper GI endoscopy revealed a huge friable rounded mass at the antrum of the stomach making it impossible to intubate the duodenum []. Biopsy and histology showed malignant epithelial cells in poorly formed glands. There was no evidence of H. pylori in the biopsy sample []. She is presently being worked up for surgery and chemotherapy.\nStaining for H. pylori in all the three patients was carried out with Haematoxillin and Eosin, and Giemsa staining, although immunohistochemistry would have been better in staining for the organism.