Two unusual cases of severe recalcitrant hypocalcemia due to aminoglycoside-induced hypomagnesemia
A 34-year-old male, diagnosed case of MDR-TB on second line ATT including kanamycin for six months, came to hospital with tingling sensation of both lower limbs and cramps of hand. He had no history of vomiting, diarrhea or oliguria. On examination, he was emaciated, pale, and had bilateral extensive lung parenchymal disease []. His investigation [] revealed hypocalcemia, hypomagnesemia, and hypermagnesuria. After detail study, kanamycin was stopped and magnesium and calcium supplementation was started. Within two weeks of treatment, patient showed improvement both biochemically and clinically.