Striatal Dopaminergic Functioning in Patients with Sporadic and Hereditary Spastic Paraplegias with Parkinsonism
A 51-yr-old male was diagnosed with SSP. When he was 33 yr old, he experienced right leg weakness and gait disturbance that progressed very slowly. On neurological examination, he presented with spasticity and muscular strength grade 4 in the lower limbs. The patient had increased DTRs in the lower limbs, with bilateral extensor plantar responses and ankle clonus. He is now 56 yr old, and his neurological signs are similar to the initial findings.