Mazabraud syndrome
25 year old lady presented with swelling and pain of left thigh of seven years duration. This gradually increased in size without weight loss or proximal muscle weakness. She did not have difficulty in walking and her activities of daily living were not affected by the pain. Examination of the left thigh revealed bowing of the left femur and a soft tissue swelling not attached to the bone. The size of the swelling was 2 × 3 cm, mobile and mildly tender to palpation.\nShe had attained menarche at the age of 13 years and had normal menstrual cycles. She was married for the past one and a half years and had not conceived yet. Her body mass index was 25.1 kg/m2 with height of 150 cm. She did not have any bony deformity or café au lait spots. On biochemical evaluation she had normal alkaline phosphatase, normal serum calcium, phosphorous and 24 hrs urine calcium, phosphorous and creatinine. She had a low level of 25 hydroxy vitamin D of 4.85 ng/ml (20.0-32.0 ng/ml) X-rays of pelvis and hip showed expansile bony swelling with cortical thinning of both tibia []. She underwent a bone scan which showed abnormal, irregularly increased tracer activity in left scapula, left tibia, left femur, pubis and left sacroiliac joints, L5 vertebra, left distal humerus and multiple ribs [], suggestive of polyostotic fibrous dysplasia. MRI of the left thigh showed well defined intramuscular mass lesions []. These lesions were hypointense on T1 weighted image and hyperintense on T2W. They were partly exophytic and measured: 28 × 41 mm in the anteromedial aspect of right adductor longus, 16 × 23 mm in the right adductor magnus at the level of mid-thigh and 9 × 10 mm in the gluteus maximus A bone biopsy [] from the left femur revealed fibrous dysplasia and a biopsy of the soft tissue mass from left thigh was confirmed as intramuscular myxoma [].