Benign breast myoepithelioma
A 20-year-old female presented to us with slowly growing breast lump for last 1 year, localized in upper outer quadrant. The lump was well defined, freely mobile and measured 3 × 3 cm in greatest dimension. The overlying skin was unremarkable. Axillary palpation was negative for lymph nodes.\nFine needle aspiration was performed. The cytological findings revealed cell rich smears comprising monomorphic loosely cohesive sheets of plasmacytoid cells, round to polygonal cells with round to ovoid eccentrically placed nuclei, finely dispersed chromatin, and moderate amount of cytoplasm. Overall findings suggested myoepithelioma, breast – plasmacytoid type [].\nOn the basis of above findings lumpectomy was done and the tissue was sent for histopathological examination. Grossly, the tissue was well circumscribed greyish white measuring 3 × 3 cm. Microscopic examination revealed tumor cells arranged in sheets with abundant myxoid stroma. The individual cells were round to polygonal, having prominent eosinophillic cytoplasm and eccentrically placed round nuclei. The diagnosis of myoepithelioma, plasmacytoid type was made on the basis of the above findings.\nOn immunohistochemistry cells were positive for S-100 protein and actin.