Coxsackievirus A6 and Hand, Foot and Mouth Disease: Three Case Reports of Familial Child-to-Immunocompetent Adult Transmission and a Literature Review
Case 2: A 37-year-old woman, sister of the patient described above, clothing store manager, with an unremarkable past medical history, was admitted to our outpatient clinic in the middle of October 2012, with a 1-day history of characteristic palm and sole rash. The symptoms were preceded by a sore throat and low-grade fever. Ten days before the onset of the first symptoms, she had contact with her brother, who at the time of the meeting was asymptomatic. The day after, the male patient developed symptoms of HFMD. He was infected by his niece suffering from HFMD 1 week before the siblings’ meeting. The female patient was absent from the family party, where the child suffering from HFMD was present. Physical examination revealed singular erythematous macular and papular lesions on the patient's soles and palms. The oral cavity was spared. No other diagnostic exam was executed due to the patient's refusal. Considering characteristic clinical manifestations and recent contact with a person suffering from HFMD, the diagnosis of HFMD was made. No treatment was prescribed as the patient did not complain of any disturbances. Complete resolution of the disease was observed within 2 weeks.