Walker Warburg syndrome associated with microphthalmos and megalophthalmos: A rare combination
A 1-day-old term female baby of primigravida was admitted with chief complaints of dehydration, inability to feed, and abnormal eye features.\nOn examination, she was found to have small anterior fossa with overriding of sutures, depressed nasal bridge, low set ears, pedal edema, skin fold at the nape of neck, widely spaced nipples, vulval anus, bilateral cortical thumb, retrognathia, short neck, generalized hypotonia. Further evaluation revealed congenital dislocation of both hip joint, hydrocephalus and hyperbilirubinemia.\nOcular examination showed right eye-microphthalmia, left eye-megalophthalmos [], flat anterior chamber (corneo endothelial touch), and non-dilating non-reacting 1.00 mm pupil. B-scan right eye shows axial length of 12 mm, left eye shows axial length of 24 mm. Intraocular pressure left eye was 18 mm Hg (perkins applanation).\nUSG skull showed hydrocephalus. Magnetic resonance imaging was suggestive of Dandy-Walker variant with small posterior fossa cyst communicating with 4th ventricle associated with gross communicating hydrocephalus []. Serum creatinine kinase level: 147 units/L (Normal range 0-25 units/L). Above findings confirm the case as WWS.