Ichthyosis associated with widespread tinea corporis: report of three\ncases
An 87-year-old female patient with congenital ichthyosiform erythroderma had been\nfollowed since 1976. Over the years she presented with erythematous-scaling patches,\nwith peripheral activity and central clearing. The diagnosis of chronic\ndermatophytosis had been established for more than 30 years. The patient underwent\nseveral treatments with systemic antifungal agents, including griseofulvin and azoles\nfor periods of 3 to 12 weeks. In addition, topical creams were used with temporary\nimprovement. In 2006 she accepted treatment with Acitretin. Partial improvement of\nerythema and desquamation was seen within 2 months; however, arciform lesions were\noccasionally seen. In September 2011, she showed signs of clinical deterioration with\nwidespread lamellar scaling on the limbs and trunk, ectropion and multiple bilateral\nerythematous round patches on the lower limbs (). Direct examination demonstrated hyaline septate hyphae with a positive\nculture for T. rubrum. Association with dermatophytosis was\ndiagnosed. Thirty days after prescription of terbinafine 250 mg qd the patient showed\ndramatic improvement of the lesions ().