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---
license: cc-by-nc-4.0
tags:
- biology
- protein
- antibody
- VHH
---
## VHHCorpus-2M
VHHCorpus-2M is a corpus that contains over two million full-length amino acid sequences of variable domain of heavy chain of heavy chain antibody (VHH).
We released VHHBERT, a VHH-specific language model pre-trained using VHHCorpus-2M on the [Hugging Face Hub](https://huggingface.co/COGNANO/VHHBERT).
Further details on VHHCorpus-2M are described in our paper "[A SARS-CoV-2 Interaction Dataset and VHH Sequence Corpus for Antibody Language Models](https://arxiv.org/abs/2405.18749).”
## Columns
| Column | Description |
| --------------- | --------------------------------------------------------------------------------- |
| VHH_sequence | Amino acid sequence of VHH |
| subject_species | Species of the subject from which VHH was collected |
| subject_name | Name of the subject from which VHH was collected |
| subject_sex | Sex of the subject from which VHH was collected |
## Links
- Project Page: https://vhh-corpus.cognanous.com
- Code: https://github.com/cognano/AVIDa-SARS-CoV-2
- Pre-trained Model: https://huggingface.co/COGNANO/VHHBERT
- Paper: https://arxiv.org/abs/2405.18749
## Citation
If you use VHHCorpus-2M in your research, please cite the following paper.
```bibtex
@inproceedings{tsuruta2024sars,
title={A {SARS}-{C}o{V}-2 Interaction Dataset and {VHH} Sequence Corpus for Antibody Language Models},
author={Hirofumi Tsuruta and Hiroyuki Yamazaki and Ryota Maeda and Ryotaro Tamura and Akihiro Imura},
booktitle={Advances in Neural Information Processing Systems 37},
year={2024}
}
```