metadata

annotations_creators:
  - expert-generated
language_creators:
  - expert-generated
language:
  - en
license:
  - cc-by-4.0
multilinguality:
  - monolingual
size_categories:
  - 10K<n<100K
source_datasets: []
task_categories:
  BORING:
    - text-classification
  NER:
    - structure-prediction
  PANELIZATION:
    - structure-prediction
  ROLES:
    - text-classification
task_ids:
  BORING:
    - multi-class-classification
  NER:
    - named-entity-recognition
  PANELIZATION:
    - parsing
  ROLES:
    - multi-class-classification

Dataset Card for sd-nlp

Dataset Card for [EMBO/sd-nlp-non-tokenized]

Dataset Description

Homepage: https://sourcedata.embo.org
Repository: https://github.com/source-data/soda-roberta
Paper:
Leaderboard:
Point of Contact: [email protected], [email protected]

Dataset Summary

This dataset is based on the content of the SourceData (https://sourcedata.embo.org) database, which contains manually annotated figure legends written in English and extracted from scientific papers in the domain of cell and molecular biology (Liechti et al, Nature Methods, 2017, https://doi.org/10.1038/nmeth.4471). Unlike the dataset sd-nlp, pre-tokenized with the roberta-base tokenizer, this dataset is not previously tokenized, but just splitted into words. Users can therefore use it to fine-tune other models. Additional details at https://github.com/source-data/soda-roberta

Supported Tasks and Leaderboards

Tags are provided as IOB2-style tags. PANELIZATION: figure captions (or figure legends) are usually composed of segments that each refer to one of several 'panels' of the full figure. Panels tend to represent results obtained with a coherent method and depicts data points that can be meaningfully compared to each other. PANELIZATION provide the start (B-PANEL_START) of these segments and allow to train for recogntion of the boundary between consecutive panel lengends. NER: biological and chemical entities are labeled. Specifically the following entities are tagged:

SMALL_MOLECULE: small molecules
GENEPROD: gene products (genes and proteins)
SUBCELLULAR: subcellular components
CELL: cell types and cell lines.
TISSUE: tissues and organs
ORGANISM: species
EXP_ASSAY: experimental assays ROLES: the role of entities with regard to the causal hypotheses tested in the reported results. The tags are:
CONTROLLED_VAR: entities that are associated with experimental variables and that subjected to controlled and targeted perturbations.
MEASURED_VAR: entities that are associated with the variables measured and the object of the measurements. BORING: entities are marked with the tag BORING when they are more of descriptive value and not directly associated with causal hypotheses ('boring' is not an ideal choice of word, but it is short...). Typically, these entities are so-called 'reporter' geneproducts, entities used as common baseline across samples, or specify the context of the experiment (cellular system, species, etc...).

Languages

The text in the dataset is English.

Dataset Structure

Data Instances

{
    "text": "".Figure6 ( A ) Cisplatin dose response curves of ( i ) MB002 , ( ii ) Daoy , and ( iii ) MIC in the absence ( EV ) or presence of SOX9 by Alamar blue . Cells were pre - conditioned with doxycycline to induce expression of SOX9 ( or EV ) prior to treatment with increasing concentrations of cisplatin . The IC50 were calculated following 5 ( MB002 and MIC ) or 3 days ( Daoy ) of treatment . Data are mean + standard deviation from 3 independent repeats , each containing 5 technical replicates . ( B ) Cisplatin dose response curves of SOX9 - expressing ( i ) Daoy and ( ii ) MIC in the absence or presence of FBW7α . Experiments and data analysis were performed as described in ( A ) ( C ) Overall survival analysis of mice bearing Daoy or Daoy - expressing dox - inducible SOX9 treated with cisplatin . The dox - preconditioned cells ( 105 cells ) were orthotopically xenografted to Nude - Foxn1nu mice and left for 1 week to prior to being treated with vehicle control or cisplatin ( 2mg / kg ) intraperitoneally for every other day for a total of 6 doses . ( D ) Heat map of the row - wise z - scores of 11 genes associated with cisplatin resistance in MB002 expressing Sox9 - WT or Sox9 - T236 / T240A . Heat map was generated using the GenePattern software . ( E ) Quantitative analysis of ATP7A , DUSP2 , and TTK mRNAs in MB002 following expression of SOX9 - WT or SOX9 - T236 / 240A . Total RNA were collected 24 hours following doxycycline treatment , from which cDNA were generated for qPCR . Data are mean mRNA level ( normalized to B2M transcript ) + standard deviation from 3 independent experiments with statistical significance were determined by Multiple comparisons 2 - way ANOVA with Bonferroni ' s post - test . ( F ) Time course western blotting of HA - SOX9 , ATP7A , DUSP2 , ERK1 / 2 pThr202 / Tyr204 and total ERK1 / 2 in MB002 cells following doxycycline induction of either EV , SOX9 - WT or SOX9 - T236 / 240A . GAPDH was used as a loading control .",
    "label_ids": {
        "entity_types": [
            "O", "O", "O", "O", "O", "O", "B-SMALL_MOLECULE", "O", "O", "O", "O", "O", "O", "O", "B-CELL", "O", "O", "O", "O", "B-CELL", "O", "O", "O", "O", "O", "B-CELL", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-GENEPROD", "O", "B-EXP_ASSAY", "I-EXP_ASSAY", "O", "O", "O", "O", "O", "O", "O", "B-SMALL_MOLECULE", "O", "O", "O", "O", "B-GENEPROD", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-SMALL_MOLECULE", "O", "O", "O", "O", "O", "O", "O", "O", "B-CELL", "O", "B-CELL", "O", "O", "O", "O", "O", "B-CELL", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-SMALL_MOLECULE", "O", "O", "O", "O", "B-GENEPROD", "O", "O", "O", "O", "O", "B-CELL", "O", "O", "O", "O", "B-CELL", "O", "O", "O", "O", "O", "O", "B-GENEPROD", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-EXP_ASSAY", "O", "O", "B-ORGANISM", "O", "B-CELL", "O", "B-CELL", "O", "O", "B-SMALL_MOLECULE", "O", "O", "B-GENEPROD", "O", "O", "B-SMALL_MOLECULE", "O", "O", "B-SMALL_MOLECULE", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-ORGANISM", "O", "O", "O", "B-GENEPROD", "B-ORGANISM", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-SMALL_MOLECULE", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-SMALL_MOLECULE", "O", "O", "B-CELL", "O", "B-GENEPROD", "O", "O", "O", "B-GENEPROD", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-GENEPROD", "O", "B-GENEPROD", "O", "O", "B-GENEPROD", "O", "O", "B-CELL", "O", "O", "O", "B-GENEPROD", "O", "O", "O", "B-GENEPROD", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-SMALL_MOLECULE", "O", "O", "O", "O", "O", "O", "O", "O", "B-EXP_ASSAY", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-GENEPROD", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-EXP_ASSAY", "I-EXP_ASSAY", "O", "B-GENEPROD", "O", "B-GENEPROD", "O", "B-GENEPROD", "O", "B-GENEPROD", "O", "B-GENEPROD", "I-GENEPROD", "I-GENEPROD", "O", "O", "O", "O", "O", "B-GENEPROD", "I-GENEPROD", "I-GENEPROD", "O", "B-CELL", "O", "O", "B-SMALL_MOLECULE", "O", "O", "O", "O", "O", "B-GENEPROD", "O", "O", "O", "B-GENEPROD", "O", "O", "O", "O", "O", "B-GENEPROD", "O", "O", "O", "O", "O", "O", "O"
        ],
        "panel_start": [
            "O", "O", "O", "B-PANEL_START", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-PANEL_START", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-PANEL_START", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-PANEL_START", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-PANEL_START", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-PANEL_START", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"
        ]
    }
}

Data Fields

text: str of the text
label_ids dictionary composed of list of strings on a character-level:
- entity_types: list of strings for the IOB2 tags for entity type; possible value in ["O", "I-SMALL_MOLECULE", "B-SMALL_MOLECULE", "I-GENEPROD", "B-GENEPROD", "I-SUBCELLULAR", "B-SUBCELLULAR", "I-CELL", "B-CELL", "I-TISSUE", "B-TISSUE", "I-ORGANISM", "B-ORGANISM", "I-EXP_ASSAY", "B-EXP_ASSAY"]
- panel_start: list of strings for IOB2 tags ["O", "B-PANEL_START"]

Data Splits

train:
- features: ['words', 'label_ids'],
- num_rows: 48_771
validation:
- features: ['words', 'label_ids'],
- num_rows: 13_801
test:
- features: ['words', 'label_ids'],
- num_rows: 7_178

Dataset Creation

Curation Rationale

The dataset was built to train models for the automatic extraction of a knowledge graph based from the scientific literature. The dataset can be used to train character-based models for text segmentation and named entity recognition.

Source Data

Initial Data Collection and Normalization

Figure legends were annotated according to the SourceData framework described in Liechti et al 2017 (Nature Methods, 2017, https://doi.org/10.1038/nmeth.4471). The curation tool at https://curation.sourcedata.io was used to segment figure legends into panel legends, tag enities, assign experiemental roles and normalize with standard identifiers (not available in this dataset). The source data was downloaded from the SourceData API (https://api.sourcedata.io) on 21 Jan 2021.

Who are the source language producers?

The examples are extracted from the figure legends from scientific papers in cell and molecular biology.

Annotations

Annotation process

The annotations were produced manually with expert curators from the SourceData project (https://sourcedata.embo.org)

Who are the annotators?

Curators of the SourceData project.

Personal and Sensitive Information

None known.

Considerations for Using the Data

Social Impact of Dataset

Not applicable.

Discussion of Biases

The examples are heavily biased towards cell and molecular biology and are enriched in examples from papers published in EMBO Press journals (https://embopress.org)

Other Known Limitations

[More Information Needed]

Additional Information

Dataset Curators

Thomas Lemberger, EMBO.

Licensing Information

CC BY 4.0

Citation Information