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[ "Triglycérides", ">", "500", "mg/dl", "avec", "ou", "sans", "utilisation", "de", "fibrate;" ]
[ 9, 3, 4, 4, 0, 0, 0, 0, 0, 5 ]
[ 10, 3, 4, 4, 0, 0, 0, 0, 0, 0 ]
NCT02671318_exc.bio_fr.txt
[ "Cholestérol", "total", ">", "300", "mg/dl", "avec", "ou", "sans", "utilisation", "de", "statine;" ]
[ 9, 10, 3, 4, 4, 0, 0, 0, 0, 0, 5 ]
[ 10, 10, 3, 4, 4, 0, 0, 0, 0, 0, 0 ]
NCT02671318_exc.bio_fr.txt
[ "Anomalies", "hépatiques;" ]
[ 1, 2 ]
[ 2, 2 ]
NCT02671318_exc.bio_fr.txt
[ "Œdème", "périphérique", "significatif;" ]
[ 0, 0, 0 ]
[ 2, 2, 0 ]
NCT02671318_exc.bio_fr.txt
[ "Anomalies", "pulmonaires", "ou", "anomalies", "mammaires", "x-rayons;" ]
[ 1, 2, 0, 1, 0, 7 ]
[ 2, 2, 0, 1, 0, 8 ]
NCT02671318_exc.bio_fr.txt
[ "Hypersensibilité", "à", "la", "formule", "du", "sirolimus" ]
[ 1, 0, 0, 0, 0, 5 ]
[ 2, 0, 0, 0, 0, 6 ]
NCT02671318_exc.bio_fr.txt
[ "Incapable", "de", "participer", "pour", "des", "raisons", "administratives" ]
[ 0, 0, 0, 0, 0, 0, 0 ]
[ 1, 0, 0, 0, 0, 0, 0 ]
NCT01424020_exc.bio_fr.txt
[ "Troubles", "psychiatriques" ]
[ 1, 2 ]
[ 1, 2 ]
NCT01424020_exc.bio_fr.txt
[ "Douleur", "au", "repos", "ou", "ischémie", "critique", "des", "membres" ]
[ 1, 2, 2, 0, 1, 2, 2, 0 ]
[ 2, 2, 2, 0, 2, 2, 2, 0 ]
NCT01424020_exc.bio_fr.txt
[ "Impossible", "de", "marcher(ex:", "sujets", "en", "fauteuil", "roulant" ]
[ 0, 2, 2, 0, 0, 0, 0 ]
[ 0, 2, 1, 0, 0, 1, 0 ]
NCT01424020_exc.bio_fr.txt
[ "Indice", "de", "masse", "corporelle(", "IMC)", "de", "35", "kg/m2", "ou", "plus." ]
[ 9, 0, 10, 10, 10, 3, 3, 4, 4, 4 ]
[ 9, 0, 10, 10, 10, 3, 3, 4, 4, 1 ]
NCT00317148_exc.bio_fr.txt
[ "Maladies", "métaboliques", "et", "endocriniennes", "importantes." ]
[ 1, 2, 0, 2, 0 ]
[ 1, 2, 0, 2, 0 ]
NCT00317148_exc.bio_fr.txt
[ "Diagnostic", "du", "cancer." ]
[ 0, 0, 1 ]
[ 1, 0, 1 ]
NCT00317148_exc.bio_fr.txt
[ "Utilisation", "de", "stéroïdes", "ou", "de", "médicaments", "qui", "interfèrent", "avec", "le", "métabolisme", "de", "l'œstrogène." ]
[ 0, 0, 5, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 1, 0, 6, 0, 0, 0, 0, 1, 0, 0, 1, 0, 1 ]
NCT00317148_exc.bio_fr.txt
[ "Utilisation", "de", "tout", "œstrogène", "systémique,", "progestatif", "ou", "DHEA", "dans", "les", "huit", "semaines", "précédant", "la", "randomisation." ]
[ 0, 0, 0, 0, 0, 0, 0, 5, 11, 12, 12, 12, 12, 12, 12 ]
[ 1, 0, 0, 1, 0, 1, 0, 1, 11, 12, 12, 12, 12, 12, 12 ]
NCT00317148_exc.bio_fr.txt
[ "Utilisation", "de", "thérapies", "alternatives", "ou", "de", "produits", "naturels", "pour", "traiter", "les", "symptômes", "postménopausiques", "au", "cours", "des", "quatre", "semaines", "précédant", "la", "randomisation." ]
[ 0, 0, 5, 0, 0, 0, 0, 0, 0, 0, 0, 0, 2, 11, 12, 12, 12, 12, 12, 12, 12 ]
[ 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 11, 12, 12, 12, 12, 12, 12, 12 ]
NCT00317148_exc.bio_fr.txt
[ "Fibres", "palpables", "ou", "prolapsus", "utérin:", "Grade", "2", "ou", "3." ]
[ 1, 2, 0, 1, 2, 9, 4, 4, 4 ]
[ 1, 2, 0, 2, 2, 9, 4, 4, 4 ]
NCT00317148_exc.bio_fr.txt
[ "Fumer", "des", "cigarette" ]
[ 1, 2, 2 ]
[ 1, 2, 2 ]
NCT00317148_exc.bio_fr.txt
[ "Le", "patient", "a", "été", "pleinement", "informé", "et", "a", "signé", "un", "formulaire", "de", "consentement", "éclairé", "approuvé", "par", "la", "CISR", "dans", "les", "7", "jours(", "jour", "7-13)", "précédant", "la", "POD", "15", "et", "il", "est", "disposé", "et", "en", "mesure", "de", "suivre", "la", "procédure", "d'étude." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 12, 12, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 12, 12, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1 ]
NCT03216447_inc.bio_fr.txt
[ "Le", "patient", "est", "un", "receveur", "primaire", "de", "transplantation", "hépatique" ]
[ 0, 0, 0, 0, 0, 0, 0, 7, 0 ]
[ 0, 0, 0, 0, 1, 0, 0, 8, 0 ]
NCT03216447_inc.bio_fr.txt
[ "Le", "patient", "est", "âgé", "de", "20", "à", "70", "ans." ]
[ 0, 0, 0, 15, 3, 3, 4, 4, 4 ]
[ 0, 0, 0, 15, 3, 3, 4, 4, 1 ]
NCT03216447_inc.bio_fr.txt
[ "Le", "patient", "doit", "être", "clairement", "conscient,", "parfaitement", "compris", "et", "capable", "de", "répondre", "au", "questionnair" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1 ]
NCT03216447_inc.bio_fr.txt
[ "Affectés", "par", "l'alcool", "ou", "la", "drogue", "au", "cours", "du", "dernier", "mois." ]
[ 1, 0, 0, 0, 0, 2, 11, 12, 12, 12, 12 ]
[ 2, 0, 2, 0, 0, 2, 11, 12, 12, 12, 1 ]
NCT02477280_exc.bio_fr.txt
[ "Maladies", "psychiatriques", "ou", "somatiques", "graves", "non", "traitées." ]
[ 1, 2, 2, 2, 0, 0, 0 ]
[ 1, 2, 2, 2, 0, 0, 1 ]
NCT02477280_exc.bio_fr.txt
[ "Pression", "artérielle", "150/95", "ou", "plus." ]
[ 9, 10, 3, 4, 4 ]
[ 9, 10, 4, 4, 4 ]
NCT02477280_exc.bio_fr.txt
[ "pouls", "irrégulier,", "ou", "impulsion", "100", "ou", "plus." ]
[ 1, 2, 0, 9, 3, 4, 4 ]
[ 2, 2, 0, 9, 3, 4, 1 ]
NCT02477280_exc.bio_fr.txt
[ "Pas", "de", "contre-indications", "selon", "la", "pilule", "Medikinet." ]
[ 0, 0, 1, 0, 0, 0, 0 ]
[ 0, 0, 2, 0, 0, 0, 1 ]
NCT02477280_exc.bio_fr.txt
[ "Diagnostic", "clinique", "concomitant", "qui", "pourrait", "considérablement", "affecter", "les", "résultats", "des", "tests." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 1, 0, 12, 0, 0, 1, 0, 0, 0, 0, 0 ]
NCT02477280_exc.bio_fr.txt
[ "La", "prescription", "simultanée", "de", "médicaments", "pour", "le", "TDAH", "ou", "de", "médicaments", "susceptibles", "d'", "affecter", "de", "façon", "significative", "les", "résultats", "des", "essais" ]
[ 0, 0, 0, 0, 5, 0, 0, 0, 0, 0, 5, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02477280_exc.bio_fr.txt
[ "leiomyome", "sous-muqueux," ]
[ 5, 0 ]
[ 6, 0 ]
NCT02361905_exc.bio_fr.txt
[ "hyperplasie", "endométriale", "avec", "atypie," ]
[ 1, 2, 0, 1 ]
[ 2, 2, 0, 0 ]
NCT02361905_exc.bio_fr.txt
[ "Antécédents", "de", "chirurgie", "utérin" ]
[ 0, 0, 8, 8 ]
[ 1, 0, 8, 8 ]
NCT02361905_exc.bio_fr.txt
[ "Diabète", "de", "type", "1" ]
[ 1, 0, 2, 2 ]
[ 2, 0, 2, 2 ]
NCT02624908_exc.bio_fr.txt
[ "Maladie", "de", "l'artère", "périphérique", "connue" ]
[ 1, 2, 2, 2, 0 ]
[ 1, 2, 2, 2, 0 ]
NCT02624908_exc.bio_fr.txt
[ "enzymes", "hépatiques", "égales", "ou", "supérieures", "à", "1,5", "fois", "la", "limite", "supérieure", "de", "la", "normale" ]
[ 9, 10, 3, 4, 3, 4, 4, 4, 4, 4, 4, 4, 4, 4 ]
[ 9, 10, 3, 4, 3, 4, 4, 4, 4, 4, 4, 4, 4, 4 ]
NCT02624908_exc.bio_fr.txt
[ "Insuffisance", "cardiaque", "chronique", "NYHA", "classe", "III", "ou", "IV" ]
[ 1, 2, 2, 9, 3, 3, 4, 4 ]
[ 2, 2, 2, 9, 3, 3, 4, 4 ]
NCT02624908_exc.bio_fr.txt
[ "Hémodialyse", "actuelle", "ou", "dialyse", "péritonéale" ]
[ 1, 0, 0, 1, 2 ]
[ 2, 0, 0, 1, 2 ]
NCT02624908_exc.bio_fr.txt
[ "Maladie", "hépatique", "terminale,", "définie", "comme", "une", "maladie", "hépatique", "aiguë", "ou", "chronique", "et", "des", "antécédents", "récents", "d'une", "des", "maladies", "suivantes:", "ascites,", "encéphalopathie,", "saignement", "varice,", "bilirubine", "égale", "ou", "supérieure", "à", "2,0", "mg/dL,", "albumine", "égale", "ou", "inférieure", "à", "3,5", "g/dL,", "temps", "de", "prothrombine", "supérieure", "ou", "égale", "à", "4", "secondes,", "INR", "supérieure", "ou", "égale", "à", "1,7", "ou", "transplantation", "hépatique", "antérieure" ]
[ 1, 2, 2, 0, 0, 0, 1, 2, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 1, 1, 1, 2, 9, 3, 4, 4, 4, 4, 4, 9, 3, 4, 4, 4, 4, 4, 9, 10, 10, 3, 4, 4, 4, 4, 4, 9, 3, 4, 4, 4, 4, 0, 7, 0, 11 ]
[ 1, 2, 2, 0, 0, 0, 1, 2, 2, 0, 0, 0, 0, 1, 0, 1, 0, 1, 0, 2, 2, 2, 2, 10, 3, 4, 4, 4, 4, 4, 9, 3, 4, 4, 4, 4, 4, 9, 10, 10, 3, 4, 4, 4, 4, 4, 9, 3, 4, 4, 4, 4, 0, 8, 8, 1 ]
NCT02624908_exc.bio_fr.txt
[ "Hypersensibilité", "connue", "ou", "soupçonnée", "aux", "produits", "d'essai", "ou", "aux", "produits", "connexes" ]
[ 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 2, 0, 0, 1, 0, 0, 1, 0, 0, 0, 1 ]
NCT02624908_exc.bio_fr.txt
[ "Femelle", "en", "âge", "de", "procréer", "qui", "est", "enceinte,", "allaite", "ou", "a", "l'intention", "de", "devenir", "enceinte", "ou", "qui", "n'utilise", "pas", "des", "méthodes", "contraceptives", "adéquates,", "comme", "l'exige", "la", "loi", "ou", "la", "pratique", "locale." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 1, 0, 1, 0, 0, 0, 0, 0, 0 ]
NCT02624908_exc.bio_fr.txt
[ "Participation", "simultanée", "prévue", "à", "tout", "autre", "essai", "clinique", "d'", "un", "médicament", "expérimental." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1 ]
NCT02624908_exc.bio_fr.txt
[ "Réception", "de", "tout", "médicament", "expérimental", "dans", "les", "30", "jours", "précédant", "la", "randomisation" ]
[ 0, 0, 0, 5, 0, 11, 12, 12, 12, 12, 12, 12 ]
[ 0, 0, 0, 1, 1, 11, 12, 12, 12, 12, 12, 12 ]
NCT02624908_exc.bio_fr.txt
[ "néoplasmes", "malins", "actuels", "ou", "passés(au", "cours", "des", "5", "dernières", "années)(", "à", "l'exception", "du", "carcinome", "basocellulaire", "et", "du", "carcinome", "cutané", "squameux)" ]
[ 1, 2, 0, 0, 0, 11, 12, 12, 12, 12, 0, 0, 0, 1, 2, 0, 0, 1, 2, 2 ]
[ 2, 2, 0, 0, 0, 11, 12, 12, 12, 0, 0, 1, 0, 2, 2, 0, 0, 2, 2, 2 ]
NCT02624908_exc.bio_fr.txt
[ "Toute", "condition", "qui,", "de", "l", "'", "avis", "de", "l", "'", "enquêteur,", "empêcherait", "le", "sujet", "de", "se", "conformer", "au", "calendrier", "et", "aux", "procédures", "des", "visites", "à", "l", "'", "audience" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02624908_exc.bio_fr.txt
[ "Antécédents", "connus", "de", "non-conformité", "au", "traitement" ]
[ 0, 0, 0, 1, 2, 0 ]
[ 2, 0, 0, 2, 2, 0 ]
NCT02624908_exc.bio_fr.txt
[ "Femmes", "enceintes,", "allaitantes", "ou", "allaitantes", "ou", "ayant", "subi", "un", "test", "positif", "de", "grossesse", "sérique", "au", "moment", "de", "l'inscription", "ou", "un", "test", "positif", "de", "grossesse", "dans", "l'urine", "le", "matin", "du", "premier", "jour", "de", "toute", "séance", "d'étude" ]
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[ 1, 1, 2, 0, 1, 0, 0, 0, 0, 9, 3, 0, 10, 10, 11, 12, 12, 12, 0, 0, 9, 3, 10, 9, 10, 1, 11, 12, 12, 12, 12, 12, 12, 12, 12 ]
NCT02531971_exc.bio_fr.txt
[ "Fumeurs(usage", "courant", "ou", "usage", "courant", "au", "cours", "des", "deux", "mois", "précédents", "de", "nicotine-contenant", "des", "substances,", "y", "compris", "des", "produits", "du", "tabac(p.", "ex.", "cigarettes,", "cigares,", "tabac", "à", "mâcher,", "gomme,", "patch", "ou", "cigarettes", "électroniques)" ]
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[ 1, 0, 0, 0, 0, 11, 12, 12, 12, 12, 12, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 1, 0, 0, 0, 0 ]
NCT02531971_exc.bio_fr.txt
[ "Participation", "à", "tout", "essai/étude", "en", "cours", "sur", "un", "médicament", "ou", "à", "tout", "essai/étude", "clinique", "sur", "un", "médicament" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0 ]
NCT02531971_exc.bio_fr.txt
[ "Antécédents", "de", "maladie", "pulmonaire", "obstructive", "chronique", "ou", "de", "cor", "pulmonaire,", "ou", "diminution", "substantielle", "de", "la", "réserve", "respiratoire,", "de", "l'hypoxie,", "de", "l'hypercapnie", "ou", "de", "la", "dépression", "respiratoire", "préexistante" ]
[ 0, 0, 1, 2, 2, 2, 0, 0, 2, 2, 0, 1, 2, 2, 2, 2, 2, 0, 2, 0, 2, 0, 0, 2, 1, 2, 0 ]
[ 1, 0, 1, 2, 2, 2, 0, 0, 2, 2, 0, 2, 2, 2, 2, 2, 2, 0, 2, 0, 2, 0, 0, 2, 1, 2, 0 ]
NCT02531971_exc.bio_fr.txt
[ "Hépatite", "B,", "C", "et", "sérologies", "VIH", "positives", "actives" ]
[ 1, 3, 3, 0, 9, 10, 3, 3 ]
[ 10, 3, 3, 0, 10, 10, 3, 3 ]
NCT02531971_exc.bio_fr.txt
[ "Test", "positif", "de", "dépistage", "des", "médicaments", "dans", "l'urine" ]
[ 9, 3, 0, 10, 0, 0, 0, 0 ]
[ 9, 3, 0, 1, 0, 0, 0, 1 ]
NCT02531971_exc.bio_fr.txt
[ "Utilisation", "de", "tout", "médicament", "sur", "ordonnance", "au", "cours", "de", "la", "séance", "0", "à", "30", "jours", "ou", "plus-le", "contre-médicament", "par", "exemple", "antihistaminiques", "ou", "corticostéroïdes", "topiques(vitamines,", "suppléments", "à", "base", "de", "plantes", "et", "médicaments", "contraceptifs", "non", "inclus)", "au", "cours", "de", "la", "séance", "0", "à", "3", "jours", "avant", "l'entrée", "dans", "l'étude" ]
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[ 1, 0, 0, 1, 0, 1, 0, 0, 12, 12, 12, 0, 12, 12, 12, 12, 12, 1, 0, 0, 6, 0, 6, 1, 1, 0, 0, 0, 0, 0, 1, 1, 0, 0, 0, 12, 12, 12, 12, 0, 12, 12, 12, 12, 12, 12, 12 ]
NCT02531971_exc.bio_fr.txt
[ "Utilisation", "de", "médicaments", "ou", "de", "traitements", "susceptibles", "d'influencer", "ou", "d'exagérer", "de", "façon", "significative", "les", "réponses", "au", "produit", "d'essai", "ou", "d'altérer", "la", "réponse", "inflammatoire", "ou", "immunitaire", "au", "produit", "ou", "aux", "agents", "considérés", "comme", "immunosuppresseurs,", "comme", "l'a", "déterminé", "l'investigateur", "médical", "72", "heures", "avant", "l'administration(p.", "ex.", "antihistaminiques,", "corticostéroïdes", "systémiques", "ou", "topiques(dans", "les", "3", "semaines", "précédant", "l'administration),", "cyclosporine,", "tacrolimus,", "médicaments", "cytotoxiques,", "immunoglobuline,", "Bacillus", "Calmette-Guerin(", "BCG),", "anticorps", "monoclonaux,", "radiothérapie)" ]
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NCT02531971_exc.bio_fr.txt
[ "Utilisation", "d'inhibiteurs", "de", "la", "monoamine", "oxydase", "21", "jours", "avant", "l'étude" ]
[ 0, 0, 0, 0, 0, 0, 11, 12, 12, 12 ]
[ 1, 6, 0, 0, 0, 1, 11, 12, 12, 12 ]
NCT02531971_exc.bio_fr.txt
[ "Utilisation", "actuelle", "d'agonistes/antagonistes", "mixtes(tels", "que", "pentazocine,", "nalbuphine", "ou", "butorphanol)", "et", "d'analgésiques", "partiellement", "agonistes(", "buprénorphine)" ]
[ 0, 0, 0, 0, 0, 5, 5, 0, 5, 0, 0, 0, 0, 5 ]
[ 1, 0, 1, 1, 0, 6, 6, 0, 6, 0, 6, 0, 1, 6 ]
NCT02531971_exc.bio_fr.txt
[ "Utilisation", "actuelle", "d'anticholinergiques", "ou", "d'autres", "médicaments", "à", "activité", "anticholinergique" ]
[ 0, 11, 0, 0, 0, 0, 0, 0, 0 ]
[ 1, 11, 6, 0, 1, 0, 0, 0, 1 ]
NCT02531971_exc.bio_fr.txt
[ "Consommation", "de", "boissons", "contenant", "de", "l'alcool,", "du", "jus", "de", "pamplemousse,", "des", "oranges", "de", "Séville", "ou", "de", "la", "quinine(par", "exemple", "de", "l'eau", "tonique)", "ou", "des", "aliments", "contenant", "des", "graines", "de", "pavot", "au", "cours", "des", "72", "dernières", "heures." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 11, 12, 12, 12, 12, 12 ]
[ 1, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 11, 12, 12, 12, 12, 1 ]
NCT02531971_exc.bio_fr.txt
[ "Don", "ou", "perte", "de", "plus", "d'une", "pinte", "de", "sang", "dans", "les", "60", "jours", "suivant", "l'entrée", "dans", "l'étude" ]
[ 1, 0, 1, 0, 0, 2, 2, 2, 2, 11, 12, 12, 12, 12, 12, 12, 12 ]
[ 1, 0, 1, 0, 0, 2, 2, 2, 2, 11, 12, 12, 12, 12, 12, 12, 12 ]
NCT02531971_exc.bio_fr.txt
[ "Toute", "réaction", "indésirable", "grave", "ou", "hypersensibilité", "antérieure", "au", "fentanyl,", "à", "la", "morphine,", "à", "la", "codéine,", "à", "l'hydrocodone,", "à", "l'hydromorphone,", "à", "l'oxycodone,", "à", "l'oxymorphone,", "à", "la", "naltrexone", "ou", "à", "la", "naloxone", "ou", "à", "l'un", "des", "ingrédients", "inactifs", "du", "TDDS(acétate", "de", "vinyle", "éthylique/", "polyester,", "adhésif", "polyacrylate,", "adhésif", "silicone,", "diméthicone", "NF", "ou", "polyoléfine)" ]
[ 0, 1, 2, 0, 0, 1, 0, 0, 5, 0, 0, 5, 0, 0, 5, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 5, 0, 0, 0, 5, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 0, 1, 2, 0, 0, 2, 2, 0, 6, 0, 0, 6, 0, 0, 6, 0, 0, 0, 6, 0, 6, 0, 6, 0, 0, 6, 0, 0, 0, 6, 0, 0, 1, 0, 0, 1, 0, 1, 0, 0, 0, 0, 1, 1, 1, 0, 1, 0, 0, 1 ]
NCT02531971_exc.bio_fr.txt
[ "Avoir", "un", "diagnostic", "de", "schizophrénie", "ou", "autre", "diagnostic", "psychiatrique", "majeur", "ou", "maladie", "mentale(p.", "ex.", "dépression", "majeure)" ]
[ 0, 0, 0, 0, 1, 0, 0, 0, 2, 0, 0, 1, 2, 0, 1, 2 ]
[ 0, 0, 0, 0, 2, 0, 0, 0, 2, 0, 0, 1, 1, 0, 1, 2 ]
NCT02531971_exc.bio_fr.txt
[ "Antécédents", "médicaux", "de", "toxicomanie", "ou", "d'abus", "d'alcool" ]
[ 0, 0, 0, 1, 0, 1, 2 ]
[ 1, 0, 0, 2, 0, 2, 2 ]
NCT02531971_exc.bio_fr.txt
[ "Toute", "condition", "qui,", "de", "l'avis", "de", "l'AMI,", "mettrait", "le", "sujet", "à", "un", "risque", "inacceptable", "de", "blessure", "ou", "le", "rendrait", "incapable", "de", "satisfaire", "aux", "exigences", "du", "protocole" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0 ]
NCT02531971_exc.bio_fr.txt
[ "Incapacité", "de", "communiquer", "ou", "de", "coopérer", "avec", "les", "enquêteurs" ]
[ 0, 14, 14, 0, 0, 14, 14, 0, 0 ]
[ 1, 14, 14, 0, 0, 14, 14, 0, 14 ]
NCT02531971_exc.bio_fr.txt
[ "Le", "sujet", "a", "une", "différence", "évidente", "dans", "la", "couleur", "de", "la", "peau", "entre", "les", "bras", "ou", "la", "présence", "d'une", "condition", "de", "la", "peau,", "les", "cheveux", "excessifs", "au", "site", "d'application(bras", "supérieur),", "les", "coups", "de", "soleil,", "les", "moles", "et", "cicatrices", "soulevées,", "les", "plaies", "ouvertes,", "les", "tissus", "cicatrisés,", "le", "tatouage,", "ou", "la", "coloration", "qui", "interférerait", "avec", "le", "placement", "d'articles", "d'essai,", "l'évaluation", "de", "la", "peau,", "ou", "les", "réactions", "au", "médicament" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 2, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 2, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02531971_exc.bio_fr.txt
[ "Défaut", "de", "passer", "le", "test", "de", "défi", "de", "la", "dépendance", "aux", "opiacés", "le", "premier", "jour", "d'étude", "de", "toute", "séance", "d'étude(c'est-à-dire", "avant", "de", "prendre", "la", "première", "dose", "de", "chlorhydrate", "de", "naltrexone).", "Chaque", "sujet", "sera", "injecté", "par", "voie", "sous-cutanée", "avec", "du", "chlorhydrate", "de", "naloxone(injection", "de", "0,8", "mg)", "et", "sera", "observé", "pendant", "45", "minutes", "pour", "les", "signes", "et", "symptômes", "de", "sevrage", "des", "opiacés." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 11, 0, 0, 0, 0, 12, 12, 12, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 11, 0, 0, 12, 0, 12, 12, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1 ]
NCT02531971_exc.bio_fr.txt
[ "Dans", "les", "4", "semaines", "précédant", "l'administration,", "l'utilisation", "de", "médicaments", "ou", "de", "traitements", "susceptibles", "d'influer", "de", "façon", "significative", "ou", "d'exagérer", "les", "réponses", "au", "produit", "d'essai", "ou", "de", "modifier", "la", "réponse", "inflammatoire", "ou", "immunitaire", "au", "produit", "ou", "aux", "agents", "considérés", "comme", "immunosuppresseurs,", "comme", "déterminé", "par", "l'investigateur", "médica" ]
[ 0, 0, 12, 12, 12, 12, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 0, 0, 12, 12, 12, 12, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0 ]
NCT02531971_exc.bio_fr.txt
[ "Antécédents", "de", "maladies", "rhumatismales", "actives" ]
[ 0, 0, 1, 2, 2 ]
[ 1, 0, 1, 2, 1 ]
NCT02760459_exc.bio_fr.txt
[ "Antécédents", "de", "lésions", "musculo-squelettiques", "antérieures", "du", "même", "genou", "pour", "l'exclusion", "des", "patients", "atteints", "d'arthrose", "secondaire", "du", "genou" ]
[ 0, 0, 1, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 2, 2, 2 ]
[ 1, 0, 1, 2, 1, 0, 0, 0, 0, 1, 0, 0, 0, 2, 2, 2, 2 ]
NCT02760459_exc.bio_fr.txt
[ "Antécédents", "de", "chirurgie", "antérieure", "sur", "le", "même", "genou" ]
[ 11, 0, 7, 8, 0, 0, 0, 0 ]
[ 1, 0, 7, 8, 0, 0, 0, 0 ]
NCT02760459_exc.bio_fr.txt
[ "Antécédents", "d'effets", "indésirables", "des", "médicaments", "à", "utiliser", "dans", "cette", "étude" ]
[ 5, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 6, 1, 1, 0, 0, 0, 0, 0, 0, 0 ]
NCT02760459_exc.bio_fr.txt
[ "Contre-indication", "à", "l'anesthésie", "médullaire" ]
[ 1, 0, 0, 8 ]
[ 2, 0, 8, 8 ]
NCT02760459_exc.bio_fr.txt
[ "Antécédents", "de", "troubles", "psychiatriques", "ou", "de", "troubles", "cognitifs" ]
[ 0, 0, 1, 2, 0, 0, 1, 2 ]
[ 1, 0, 1, 2, 0, 0, 1, 2 ]
NCT02760459_exc.bio_fr.txt
[ "Contre-indication", "aux", "corticostéroïdes" ]
[ 1, 0, 5 ]
[ 2, 0, 6 ]
NCT02760459_exc.bio_fr.txt
[ "Diabète", "mal", "contrôlé(HbA1C", ">", "7,5)" ]
[ 1, 2, 2, 3, 4 ]
[ 2, 2, 10, 3, 0 ]
NCT02760459_exc.bio_fr.txt
[ "Hypertension", "artérielle", "mal", "contrôlée" ]
[ 1, 2, 2, 2 ]
[ 1, 2, 2, 2 ]
NCT02760459_exc.bio_fr.txt
[ "Antécédents", "de", "cardiopathie", "ischémique", "ou", "de", "maladie", "artérielle", "périphérique", "ou", "de", "maladie", "cérébrovasculaire" ]
[ 0, 0, 1, 2, 0, 0, 1, 2, 2, 0, 0, 1, 2 ]
[ 1, 0, 2, 2, 0, 0, 1, 2, 2, 0, 0, 1, 2 ]
NCT02760459_exc.bio_fr.txt
[ "Insuffisance", "hépatique(Score", "de", "l'enfant-Pugh", ">", "5)" ]
[ 1, 2, 10, 10, 3, 4 ]
[ 2, 2, 10, 10, 3, 4 ]
NCT02760459_exc.bio_fr.txt
[ "Insuffisance", "rénale(clairance", "de", "la", "créatinine", "<", "30", "mL/min)" ]
[ 1, 2, 10, 10, 10, 3, 4, 4 ]
[ 2, 10, 10, 10, 10, 3, 4, 4 ]
NCT02760459_exc.bio_fr.txt
[ "Antécédents", "de", "cataractes,", "de", "glaucome", "ou", "d'hypertension", "oculaire" ]
[ 0, 2, 2, 0, 1, 0, 0, 2 ]
[ 2, 2, 2, 0, 2, 0, 2, 2 ]
NCT02760459_exc.bio_fr.txt
[ "Antécédents", "d'utilisation", "de", "stéroïdes", "ou", "de", "médicaments", "immunosuppresseurs", "dans", "les", "6", "mois", "suivant", "la", "chirurgi" ]
[ 0, 0, 0, 5, 0, 0, 5, 5, 11, 12, 12, 12, 12, 12, 12 ]
[ 1, 1, 0, 6, 0, 0, 1, 6, 11, 12, 12, 12, 12, 12, 12 ]
NCT02760459_exc.bio_fr.txt
[ "Tole", "complète", "confirmée", "par", "ultrason" ]
[ 0, 0, 0, 0, 7 ]
[ 0, 0, 0, 0, 8 ]
NCT01630954_inc.bio_fr.txt
[ "Grossesse(un", "test", "de", "grossesse", "sérique", "ou", "urinaire", "négatif", "doit", "être", "disponible", "pour", "les", "femmes", "en", "âge", "de", "procréer", "avant", "l'inclusion", "dans", "l'étude)", "ou", "allaitement" ]
[ 1, 9, 0, 10, 10, 0, 10, 3, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 11, 12, 0, 12, 0, 0 ]
[ 1, 9, 0, 10, 10, 0, 10, 3, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 11, 12, 0, 12, 0, 1 ]
NCT02596555_exc.bio_fr.txt
[ "Femmes", "en", "âge", "de", "procréer", "qui", "ne", "pratiquent", "pas", "une", "contraception", "médicalement", "acceptée", "très", "efficace", "pendant", "l'essai", "et", "un", "mois", "après" ]
[ 15, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 11, 12, 0, 0, 12, 0 ]
[ 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 11, 12, 0, 0, 12, 0 ]
NCT02596555_exc.bio_fr.txt
[ "Antécédents", "d'hypersensibilité", "au", "médicament", "expérimental", "ou", "à", "tout", "médicament", "ayant", "une", "structure", "chimique", "similaire", "ou", "à", "tout", "excipient", "présent", "sous", "forme", "pharmaceutique", "du", "médicament", "expérimental" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 1, 2, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 0, 1 ]
NCT02596555_exc.bio_fr.txt
[ "Participation", "à", "un", "autre", "essai", "clinique", "au", "cours", "du", "présent", "essai", "clinique", "ou", "au", "cours", "des", "trois", "derniers", "mois" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 12, 0, 0, 0, 0, 0, 12, 12, 12, 12 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 12, 0, 0, 0, 0, 0, 12, 12, 12, 12 ]
NCT02596555_exc.bio_fr.txt
[ "Troubles", "médicaux", "ou", "psychologiques", "qui", "ne", "permettraient", "pas", "l", "'", "achèvement", "du", "procès", "ou", "la", "signature", "d", "'", "un", "consentement", "éclairé" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02596555_exc.bio_fr.txt
[ "Utilisation", "d'un", "agent", "fibrinolytique,", "d'une", "thrombectomie", "chirurgicale,", "d'une", "aspiration", "ou", "d'une", "lyse", "du", "thrombus", "interventionnelle(cathéter-dirigé),", "ou", "d'un", "filtre", "à", "cava", "pour", "traiter", "l'épisode", "index", "de", "PE" ]
[ 0, 0, 0, 0, 0, 7, 8, 0, 7, 0, 0, 7, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 1, 1, 0, 1, 1, 8, 8, 1, 8, 0, 1, 8, 0, 1, 1, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0 ]
NCT02596555_exc.bio_fr.txt
[ "Traitement", "avec", "tout", "anticoagulant", "à", "dose", "thérapeutique", "pendant", "plus", "de", "48", "heures", "avant", "l'inscription" ]
[ 7, 0, 0, 5, 0, 0, 0, 11, 12, 12, 12, 12, 12, 12 ]
[ 8, 0, 0, 6, 0, 0, 1, 11, 12, 12, 12, 12, 12, 12 ]
NCT02596555_exc.bio_fr.txt
[ "Nécessité", "d'un", "traitement", "à", "long", "terme", "avec", "une", "héparine", "de", "faible", "poids", "moléculaire,", "des", "antagonistes", "de", "la", "vitamine", "K", "ou", "de", "la", "NOAC,", "pour", "une", "indication", "autre", "que", "l'épisode", "de", "PE", "index,", "ou", "pour", "des", "agents", "antiplaquettaires", "à", "l'exception", "de", "l'acide", "acétylsalicylique", "à", "une", "dose=100", "mg/jour;" ]
[ 0, 0, 7, 0, 0, 0, 0, 0, 5, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 5, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 1, 1, 7, 0, 0, 0, 0, 0, 6, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 1, 1, 0, 0, 1, 0 ]
NCT02596555_exc.bio_fr.txt
[ "Saignement", "actif", "ou", "risque", "de", "saignement", "significatif", "connu(par", "exemple,", "ulcère", "gastro-intestinal,", "néoplasmes", "malins,", "blessures", "ou", "chirurgies", "récentes", "du", "cerveau,", "de", "la", "moelle", "épinière", "ou", "des", "yeux,", "saignements", "intracrâniens", "récents,", "varices", "d'oesophage", "connues", "ou", "suspectées,", "anévrismes", "ou", "anomalies", "vasculaires", "intraspinales", "ou", "intracrâniennes)" ]
[ 1, 2, 0, 0, 0, 2, 0, 0, 0, 1, 2, 1, 2, 1, 0, 7, 0, 0, 0, 0, 2, 0, 0, 0, 0, 0, 1, 2, 0, 1, 2, 0, 0, 0, 1, 0, 1, 2, 0, 0, 0 ]
[ 2, 2, 0, 0, 0, 2, 0, 1, 0, 2, 2, 2, 2, 1, 0, 2, 0, 0, 0, 0, 2, 0, 2, 0, 0, 0, 2, 2, 0, 1, 2, 0, 0, 0, 2, 0, 1, 2, 2, 0, 2 ]
NCT02596555_exc.bio_fr.txt
[ "Vannes", "cardiaques", "artificielles", "nécessitant", "un", "traitement", "avec", "un", "anticoagulant" ]
[ 1, 2, 0, 0, 0, 7, 0, 0, 5 ]
[ 1, 2, 0, 1, 0, 7, 0, 0, 6 ]
NCT02596555_exc.bio_fr.txt
[ "Insuffisance", "rénale", "avec", "clairance", "estimée", "de", "la", "créatinine", "<", "30", "ml/min/1,73m2" ]
[ 1, 2, 0, 9, 0, 0, 10, 10, 3, 4, 4 ]
[ 2, 2, 0, 9, 0, 0, 10, 10, 3, 4, 4 ]
NCT02596555_exc.bio_fr.txt
[ "Maladie", "hépatique", "chronique", "avec", "des", "taux", "d'aminotransférases", "deux", "fois", "ou", "plus", "supérieurs", "à", "la", "limite", "supérieure", "locale", "de", "l'intervalle", "normal" ]
[ 1, 2, 0, 0, 0, 9, 10, 0, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4 ]
[ 1, 2, 0, 0, 0, 9, 10, 0, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4 ]
NCT02596555_exc.bio_fr.txt
[ "Administration", "concomitante", "d'", "inhibiteurs", "puissants", "de", "P-glycoprotéine", "comme", "le", "kétoconazole,", "la", "cyclosporine,", "l'itraconazole", "ou", "la", "dronedarone" ]
[ 0, 0, 0, 0, 0, 0, 5, 0, 0, 5, 0, 5, 5, 0, 0, 5 ]
[ 0, 12, 0, 0, 0, 0, 6, 0, 0, 6, 0, 6, 6, 0, 0, 6 ]
NCT02596555_exc.bio_fr.txt
[ "Incontestation", "ou", "incapacité", "à", "suivre", "le", "traitement", "ou", "les", "visites", "de", "suivi" ]
[ 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 2, 0, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02596555_exc.bio_fr.txt
[ "Espérance", "de", "vie", "inférieure", "à", "6", "moi" ]
[ 0, 14, 10, 3, 4, 4, 4 ]
[ 14, 14, 10, 3, 4, 4, 4 ]
NCT02596555_exc.bio_fr.txt
[ "Tous", "les", "patients", "qui", "étaient", "en", "fauteuil", "roulant", "liés", "préopératoirement" ]
[ 0, 0, 0, 0, 0, 0, 14, 14, 0, 0 ]
[ 0, 0, 0, 0, 0, 0, 1, 1, 0, 1 ]
NCT02926235_exc.bio_fr.txt
[ "Tous", "les", "patients", "qui", "ne", "peuvent", "pas", "participer", "à", "un", "programme", "de", "physiothérapie", "externe", "pendant", "3", "jours", "par", "semaine", "après", "la", "chirurgi" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 8, 0, 11, 12, 12, 0, 12, 12, 12, 12 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 8, 0, 11, 12, 12, 0, 12, 12, 12, 12 ]
NCT02926235_exc.bio_fr.txt
[ "Les", "patients", "sont", "en", "mesure", "de", "fournir", "un", "consentement", "écrit", "éclairé", "signé", "et", "daté", "avant", "toute", "procédure", "spécifique", "à", "l'étude." ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1 ]
NCT03338855_inc.bio_fr.txt
[ "Les", "femmes", "sont", "ménopausées(définies", "comme", "étant", "au", "moins", "un", "an", "après", "l'", "arrêt", "des", "règles)", "et", "âgées", "de", "45", "ans", "et", "de", "70", "ans.", "Les", "hommes", "sont", "âgés", "de", "40", "ans", "et", "de", "70", "ans.", "Les", "patients", "doivent", "avoir", "des", "veines", "appropriées", "pour", "la", "canulation", "ou", "la", "veine", "veine", "répétée." ]
[ 0, 15, 0, 1, 0, 0, 0, 12, 12, 12, 0, 12, 12, 12, 12, 0, 15, 0, 4, 4, 4, 4, 4, 4, 0, 15, 0, 15, 0, 4, 4, 4, 0, 4, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ 0, 15, 0, 1, 0, 0, 0, 12, 12, 12, 0, 12, 12, 12, 0, 0, 1, 0, 4, 4, 4, 4, 4, 0, 0, 15, 0, 16, 0, 4, 4, 4, 0, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1 ]
NCT03338855_inc.bio_fr.txt