This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: miscellaneous, Subject name: Pathology
[{'content': 'The anticoagulant of choice for performing coagulation studies is- \nSelect and explain. \nA. EDTA, B. Heparin J & K 05, C. Tri sodium citrate, D. Double oxalate', 'role': 'user'}, {'content': 'Answer: C \nExplanation: I. Calcium chelating agents * Ethylene diamine tetraacetic acid (EDTA):- RBC count, total leucocyte count, eosinophil count, platelet count. Hemoglobin, HbF estimation, and Hb electrophoresis. * Double oxalate (mixtures of ammonium oxalate and potassium oxalate):- Since the morphology of the blood cells is not well preserved, it is now replaced by EDTA * Sodium citrate solution:- Coagulation studies, ESR by Westergren method, blood bank {ACD (acid citrate dextrose) solution was used and now replaced by citrate phosphate dextrose adenine (CPDA)} *Sodium fluoride:- Estimation of blood sugar II. Heparin:- Osmotic fragility test, red cell enzyme studies (e.g. G6PD and PK deficiency), electrolyte estimation, aerial blood gas analysis. Ref: RAM DAS NAYAK 2nd Ed. Pg no:336', 'role': 'assistant'}]