This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Blood, Subject name: Pathology
[{'content': 'Thrombotic thrombocytopenic purpura involves all except? \nSelect and explain. \nA. Microangiopathy, B. Neural dysfunction, C. High complement level, D. Intravascular hemolysis', 'role': 'user'}, {'content': "Answer: C \nExplanation: Ans. is 'c' i.e., High complement level * Platelet associated IgG and complement levels are usually normal in TTP.Thrombotic thrombocytopenia purpura (TTP) / Moschcowitz disease* TTP is included among group of diseases called thrombotic microangiopathies. Small vessels like terminal arterioles and capillaries are involved.* Patients with TTP are deficient in an enzyme called ADAMTSB.13 also known as vWF metalloprotease leading to platelet macroaggregate formation throughout the microcirculation.Clinical features* TTP is characterized by a pentad of1. Microangiopathic hemolytic anemia2. Thrombocytopenia3. Neurological symptoms (platelet thrombin in cerebral vessels)4. Renal dysfunction5. Fever* There is intravascular hemolysis.* BT is raised with normal PT and aPTT.", 'role': 'assistant'}]