This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': "Hepatomegaly is an essential feature of \nSelect and explain. \nA. Von Gierke's disease, B. Nieman Pick disease, C. Hurler syndrome, D. Hepatic porphyria", 'role': 'user'}, {'content': "Answer: D \nExplanation: Hepatomegaly is an essential feature of von Gierke's disease (all glycogen storage diseases except type 2, 5, 7), Hurler (Scheic) syndrome (& all mucopolysaccharidosis) and Nieman-Pick disease. But the hepatic involvement of hepatic porphyria is variable. Patients with chronic hepatic porphyria (porphyria cutanea tarda), however may show liver enlargement d/t fatty infiltration but frank sings of hepatomegaly and iron overload are rare.", 'role': 'assistant'}]