This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Bleeding disorders with ↑ APTT and ↑PT:a) Factor 13 deficiencyb) Severe liver diseasec) Immune thrombocytopenic purpurad) Leiden (Factor V) deficiency \nSelect and explain. \nA. c, B. bd, C. ab, D. ac', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Prothrombin time assesses factor V, VII, X & II ; all of which are synthesized in liver.\nPTT assess measures activity of factor V, VIII, IX, X, XI, XII & II some of which (II, VIII, VII, X, V) are synthesized in liver.\nSo, in liver diseases both aPTT as well as PT are increased.', 'role': 'assistant'}]