This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of protein and amino acid, Subject name: Biochemistry
[{'content': 'All of the following are post-translational effects of histone except \nSelect and explain. \nA. Acylation, B. Methylation, C. Phosphorylation, D. Glycosylation', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Histones are the Most Abundant Chromatin ProteinsHistones are a small family of closely related basic proteins. Nucleosomes contain four major types of histones: H2A, H2B, H3, and H4.These four core histones are subject to at least six types of covalent modification or posttranslational modifications (PTMs): acetylation, methylation, phosphorylation, ADP-ribosylation, monoubiquitylation, and sumoylation. These histone modifications play an impoant role in chromatin structure and function.Ref: Harper&;s Biochemistry; 30th edition; Chapter 35 DNA Organization, Replication, & Repair', 'role': 'assistant'}]