This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Which of the following supplements is used in the treatment of multiple carboxylase deficiency? \nSelect and explain. \nA. Biotin, B. Pyridoxin, C. Thiamine, D. Folic acid', 'role': 'user'}, {'content': "Answer: A \nExplanation: Biotin is a water soluble vitamin that is a cofactor for all carboxylase enzymes. Multiple carboxylase deficiency results from deficient carboxylase activity and is treated by biotin. Ref: Nelson's Textbook of Pediatrics 17th Edition, Page 412; Textbook of Clinical Pediatrics, Volume 1 By A. Y. Elzouki, F. B. Stapleton, R. J. Whitley, William Oh, H. A. Harfi, H. Nazer, 2011, Page 457", 'role': 'assistant'}]