This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Psychiatry
[{'content': "Which of the following gene is associated with Alzheimer's disease ? \nSelect and explain. \nA. APOE1, B. APOE, C. APOE3, D. APOE4", 'role': 'user'}, {'content': "Answer: D \nExplanation: Alzheimer's disease is caused by mutation in :\n\nAPOE4 gene\nPresenilin 1 : Chromosome 14\nPresenilin 2\xa0: Chromosome 1\nAPP4 ( Amyloid precursor protein - 4 ) :\xa0Chromosome 21", 'role': 'assistant'}]