This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Renal physiology, Subject name: Physiology
[{'content': 'Proximal convoluted tubule have which type of aquaporins \nSelect and explain. \nA. Aquaporin 1, B. Aquaporin 2, C. Aquaporin 5, D. Aquaporin 9', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Aquaporin-1 is localized to both the basolateral and apical membrane of the proximal tubules and its presence allows water to move rapidly out of the tubule along the osmotic gradients set up by active transpo of solutes, and isotonicity is maintained. Because the ratio of the concentration in tubular fluid to the concentration in plasma (TF/P) of the nonabsorbable substance inulin is 2.5 to 3.3 at the end of the proximal tubule, it follows that 60-70% of the filtered solute and 60-70% of the filtered water has been removed by the time the filtrate reaches this point.Ref: Ganong&;s review of medical physiology,23rd edition, page: 652', 'role': 'assistant'}]