This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Human Immunodeficiency Virus, Subject name: Microbiology
[{'content': 'Fatal familial insomnia is associated with: \nSelect and explain. \nA. Prion disease, B. Degenerative diseases, C. Neoplastic diseases, D. Vascular diseases', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Prion diseaseFatal familial insomnia: Patients with this illness present with intractable insomnia, dysautonomia, dementia and motor paralysis. Death occurs within 6 months to 3 years following presentation. The clinical presentation of the disease, however, varies widely; hence definitive diagnosis of the condition is made by genotyping.", 'role': 'assistant'}]