This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Physiology & Histology, Subject name: Gynaecology & Obstetrics
[{'content': 'Softening of the vaginal portion of the cervix: \nSelect and explain. \nA. Goodells sign, B. Chadwicks sign, C. Hegar s sign, D. Piskaceks sign', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. a. GoodelPs signThe cervix contains more of fibrous tissue and collagen than the muscle fibers.Cervix contains mainly collagen and only 10% of muscle fibers.In late pregnancy and at term, under the influence of prostaglandin, collagenase dissolves collagen into fluid form and renders the cervix soft and stretchable during labor.Extra MileChadwick's sign: In early pregnancy, increased vascularity within the cervix stroma beneath the epithelium creates an ectocervical blue tint that is called as Chadwick sign.Goodells sign: Cervical edema leads to softening of the cervixHegar's sign: Isthmic softening is cervix.", 'role': 'assistant'}]