This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hypolipidemic, Subject name: Pharmacology
[{'content': 'What is TRUE about Lovastatin \nSelect and explain. \nA. Inhibits HMG CoA synthetase, B. Inhibits HMG CoA reductase, C. Myositis may result from its prolonged use, D. Decrease synthesis of cholesterol and causes lenticular opacity', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., Inhibits HMG CoA reductase 'c' i.e., Myositis results from prolonged use 'd' i.e., Decrease synthesis of cholesterol and cause lenticular opacityLovastatin:Mechanism of actionInhibition of HMGCoA reductase Mode of actionDecreased cholesterol synthesis Increased LDL receptors Lipoproteins affectedLDL- DecreasedVLDL- DecreasedTG- DecreasedHDL- IncreasedSite EffectsHepatic dysfunction Severe myositis, | CPK Lens opacities ContraindicationsImpaired renal function andIn combination with Gemfibrozil or Nicotinic acid Risk of myositis is increased in these conditions", 'role': 'assistant'}]