This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Psoriasis, Subject name: Dental
[{'content': 'Efalizumab disrupts the interaction between which of the following adhesion molecules? \nSelect and explain. \nA. LFA-3 and ICAM-1, B. LFA-1 and ICAM-1, C. LFA-3 and ICAM-3, D. LFA-3 and CD2', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Agents targeting co-stimulatory molecules and under development for psoriasis include: Efalizumab, -A gainst CD11a (LFA-1), which blocks CD11a-ICAM-1 binding and may inhibit lymphocyte binding to endothelium the same mechanism. Alefacept - Inhibiting the normal CD2/LFA-3 interaction.', 'role': 'assistant'}]