This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Gene therapy is used for \nSelect and explain. \nA. All of the below, B. Sickle cell anemia, C. Thalassemia, D. Cystic fibrosis', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Gene transfer is a novel area of therapeutics in which the active agent is a nucleic acid sequence rather than a protein or small molecule. Most gene transfers are carried out using a vector or gene delivery vehicle because delivery of naked DNA or RNA to a cell is an inefficient process. More clear-cut success has been achieved in a gene therapy trial for another form of SCID, adenosine deaminase (ADA) deficiency. Other diseases likely to be amenable to transduction of hemaopietic stem cells (HSCs) include\n• Wiskott-Aldrich syndrome\n• Chronic granulomatous disease\n• Sickle cell disease\n• Thalassemia.\nClinical trials using recombinant adeno-associated vectors are now ongoing for muscular dystrophies, alpha-1 antitrypsin deficiency, lipoprotein lipase deficiency, hemophilia B, and a form of congenital blindness called Leber’s congenital amaurosis.', 'role': 'assistant'}]