This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'The first step in liver’s metabolism of fructose is ? \nSelect and explain. \nA. Isomerization of glucose, B. Phosphorylation to fructose 1, 6 bisphosphate by ATP, C. Phosphorylation to fructose 6 phosphate by ATP, D. Phosphorylation to fructose 1 phosphate by ATP', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Fructose metabolism', 'role': 'assistant'}]