This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Retina, Subject name: Ophthalmology
[{'content': 'Which of the following is True regarding intraocular retinoblastoma? \nSelect and explain. \nA. 60% are familial and the rest about 40% occur sporadically., B. Leukocoria or yellowish-white pupillary reflex is 2nd commonest presenting feature., C. ICRB is presently being followed to decide the treatment modality, D. All of the above', 'role': 'user'}, {'content': "Answer: C \nExplanation: Retinoblastoma MC ocular tumor of childhood. 40% are hereditary, aka Germline retinoblastoma. B/L, multifocal, earlier presentation 60% are non hereditary or sporadic U/L, later presentation C/F: Leucocoria(Amaurotic cat's eye pupil)- MC presentation Strabismus(2nd MC) Neo vascular glaucoma(3rd MC) International classification of retinoblastoma (ICRB), which is presently being followed worldwide to decide the treatment modality.", 'role': 'assistant'}]