This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Dermatitis, Subject name: Dental
[{'content': 'Acanthosis involves \nSelect and explain. \nA. Stratum corneum, B. Stratum spinosum, C. Stratum granulosum, D. Stratum lucidum', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Acanthosis is used to describe increase in the number of cells in the Malphigian or prickle cell layer of the epidermis Acanthosis is diffuse epidermal hyperplasia (thickening of the skin). It implies increased thickness of the Malpighian layer (stratum basale and stratum spinosum). Acanthosis nigricans is often associated with type 2 diabetes, and is usually observed in the back of neck, axilla, and other folded regions of the skin. Ref: Harrison 20th edition pg 1246', 'role': 'assistant'}]