This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy, Subject name: Pharmacology
[{'content': 'Jarisch-Herxhemer reaction is seen in syphilis with: \nSelect and explain. \nA. Tetracyclines, B. Penicillins, C. Co-trimoxazole, D. Sulfonamides', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Jarisch-Herxheimer reaction Penicillin injected in a syphilitic patient (paicularly secondary syphilis) may produce shivering, fever, myalgia, exacerbation of lesions, even vascular collapse. This is due to sudden release of spirochetal lytic products and lasts for 12-72 hours. It does not recur and does not need interruption of therapy Aspirin and sedation afford relief of symptoms. Essentials of medical pharmacology K D Tripathi Sixth edition Pg no 698', 'role': 'assistant'}]