This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Congenital CNS malformations, Subject name: Pediatrics
[{'content': 'Neural tube defects have which one of the following inheritance patterns? \nSelect and explain. \nA. Autosomal dominant, B. Autosomal recessive, C. X-linked recessive, D. Multifactorial', 'role': 'user'}, {'content': 'Answer: D \nExplanation: - Neural tube defects: Occurs d/t failure of proper closure of neural tube Show multifactorial inheritance. Examples: 1. Meningocele 2. Meningomyelocele 3. Anencephaly 4. Spina bifida occulta 5. Iniencephaly 6. Encephalocele - Extra Edge: Other conditions having multifactorial inheritance are Hypeension Diabetes mellitus Most of the congenital hea diseases etc', 'role': 'assistant'}]