This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'True about first order kinetics of elimination - \nSelect and explain. \nA. Constant amount of drug is eliminated, B. Rate of elimination is not related to plasma concentration, C. Clearance remains constant, D. Half life decreases with decreased concentration', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans. C. Clearance remains constantFirst order kinetics:Rate of elimination is directly propoional to Plasma Concentration.Clearance remains constant -Due to increasing plasma concentration, increases the rate of elimination propoionately.(CL = rate of elimination / Plasma Conc).Half life remains constant -Due to time required to reduce plasma concentration to half is same (rate of eliminationchange propoionately with plasma concentration).', 'role': 'assistant'}]