This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Surgery
[{'content': "Which of the following acrries the least risk of Colonic malignancy ? \nSelect and explain. \nA. Familial adenomatous polyposis, B. Gardner's syndrome, C. Villous adenoma, D. Peutz-Jeghers syndrome", 'role': 'user'}, {'content': "Answer: D \nExplanation: .PEUTZ-JEGHER'S POLYP * It is common in small intestine (jejunum) but can also occur in large intestine. * Features are multiple, familial, hamaomatous intestinal polyps. * Asssociated with melaenosis of the oral mucosa, lips (lower lip) and occasionally digits (not in tongue). * Microscopically it contains tree like branching filaments of mucosa with smooth muscle wall. * It can occasionally turn into malignancy. ref:SRB&;S manual of surgery,ed 3,pg no 831", 'role': 'assistant'}]