This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Single Gene Disorders, Subject name: Pathology
[{'content': 'In classical Mendelian inheritance, autosomal dominant disease characterized by: \nSelect and explain. \nA. Complete penetrance, B. Parents are unaffected, C. Very early onset in life, D. Variable expressivity', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Autosomal dominant disease -Variable expressivity -Incomplete penetrance -Both parents are affected -No skipping of generations', 'role': 'assistant'}]