This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': "Giant hypertrophy of gastric mucosa similar to brain surface is seen in - \nSelect and explain. \nA. Peptic ulceration, B. Carcinoma stomach, C. Menetrier's disease, D. Liomyosarcoma", 'role': 'user'}, {'content': 'Answer: C \nExplanation: Menetrier disease\xa0\n\nIt is characterized by giant cerebriform (similar to brain surface) enlargement of rugal folds of gastric mucosa.\nEnlargement of rugal folds is due to profound hyperplasia of surface mucous cells → gastric secretion & contain excessive mucus.\nThere is accompanying glandular atrophy\xa0→ gastric disease is more common in males in the fourth to sixth\xa0decades.\nThe hypertrophic change may predominanty involve the body, fundus or antrum or may affect the entire stomach.\nPatients develop protein-losing gastropathy accompanied hypoalbuminemia and edema.\nInfrequently, the mucosal hyperplasia becomes metaplastic, providing a soil for the development of gastric carcinoma.', 'role': 'assistant'}]