This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti-Cancer, Subject name: Pharmacology
[{'content': 'Which one of the following compounds increases the synthesis of tumor necrosis factor, leading to activation of phagocytosis in patients with chronic granulomatous disease? \nSelect and explain. \nA. Aldesleukin, B. Cyclosporine, C. Interferon-gamma, D. Infliximab', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Interferon-gamma 1b (recombinant form) is used in chronic granulomatous disease to decrease infection liability because it increases the formation of tumor necrosis factor (TNF).Infliximab is a monoclonal antibody to TNF used in rheumatoid arthritis, and its use may lead to an increased infection rate. Aldesleukin is a recombinant form of IL-2.', 'role': 'assistant'}]