This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Intersex, Subject name: Gynaecology & Obstetrics
[{'content': "Lethargic, hypoglycemic female neonate with scrotum-like labia majora is suggestive of- \nSelect and explain. \nA. Congenital adrenal hyperplasia, B. Turner's syndrome, C. Klinefelter's syndrome, D. Ovo-testicular disorder of sexual development", 'role': 'user'}, {'content': 'Answer: A \nExplanation: Above history point towards diagnosis of Congenital adrenal hyperplasia: - Due to deficiency of enzyme 21-Hydroxylase There is lack of coisol production resulting in excess of Adrenocoicotropic hormone (ACTH) production from pituitary. Features: - Enlarged clitoris Presence of penile urethra or hypospadias Associated metabolic abnormality -Salt wasting (hyponatremia, hyperkalemia) Fusion of Labia majora Lethargic hypoglycemic females. Investigations: - Karyotype is 46 XX Serum estimation Sex chromatin study reveals positive Barr body Sonographic evaluation', 'role': 'assistant'}]