This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'The class of antibodies that plays an important role in type I hypersensitivity reactions is _____. \nSelect and explain. \nA. IgA, B. IgD, C. IgE, D. IgG', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Although IgE is the least prevalent immunoglobulin in the body, it is the major antibody mediator of type I hypersensitivity\xa0reactions. These reactions are caused primarily by prior sensitization and the accumulation of IgE to a specific allergen.', 'role': 'assistant'}]