This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
[{'content': "Which of the following has the least malignant potential? \nSelect and explain. \nA. Adenomatous polyps in HNPCC, B. Juvenile polyps in Juvenile Polyposis Syndrome, C. Adenomatous Polyps in Familial colonic Polyposis, D. Hamaomatous Polyps in Peutz Jegher's Syndrome", 'role': 'user'}, {'content': "Answer: D \nExplanation: Among the options given in the question hamaomatous polyps in Peutz Jegher's syndrome has only a small chance of being malignant (39%). Juvenile Polyps given in this question are not solitary polyps, but pa of juvenile polyposis syndrome, which has a risk of about 30 to 60 % to develop into a carcinoma. In HNPCC, there 80% lifetime risk of developing colorectal carcinoma. Adenomatous polyps in Familial adenomatous polyposis, if left untreated has a 100% relative risk of turning into malignancy. Ref: Current Surgical Diagnosis& Treatment, 12th Edition, Page 696, 697, 709, 710; Cancer Epidemiology and Prevention By David Schottenfeld, 3rd Edition Page 568; Principles and Practice of Clinical Medicine in Asia: Treating the Asian Patient By Joseph Jao Yiu Sung, page 276; Harrison's Principles of Internal Medicine 18th edition, Chapter 91.", 'role': 'assistant'}]