This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of carbohydrate, Subject name: Biochemistry
[{'content': 'Mc Ardles disease is due to deficiency of \nSelect and explain. \nA. Liver phosphorylase, B. Muscle phosphorylase, C. Glycogen phosphorylase, D. Galactase', 'role': 'user'}, {'content': "Answer: B \nExplanation: Glycogen storage diseases TYPE NAME DEFICIENT ENZYME CLINICAL FEATURES Type I von Gierke's disease Glucose-6-phosphatase Fasting hypoglycemia; hepatomegaly,thrombocyte dysfunction. Type II Pompe's disease Lysosomal maltase Accumulation of glycogen in lysosomes of liver, hea and muscle; death before 2 years Type III Limit dextrinosis (Cori's disease) Debranching enzyme Highly branched dextrin accumulates; Fasting hypoglycemia; hepatomegaly Type IV Amylopectinosis (Anderson's disease) Branching enzyme Glycogen with few branches; hepatosplenomegaly; mild- -hypoglycemia; death by age of 5 Type V McArdle's disease Muscle phosphorylase Excercise intolerance; accumulation of glycogen in muscles Type VI Her's disease Liver phosphorylase Mild hypoglycemia; hepatomegaly; better prognosis than other types REF: DM VASUDEVAN TEXTBOOK OF BIOCHEMISTRY,EIGHTH EDITION,PG.NO.,144.", 'role': 'assistant'}]