This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pathology
[{'content': 'HPV oncogene expression is \nSelect and explain. \nA. E1E2, B. E1E3, C. E3E5, D. E6E7', 'role': 'user'}, {'content': 'Answer: D \nExplanation: The oncogenic potential of HPV can be related to production of two early viral genes E6&E7 Together they interact with variety of growth regulating proteins encoded by protooncogene and tumour suppressor genes E6- binds to and mediate the degradation of p53 E7-binds to Rb protein and release E2F transcription factor,also inactivates the CDKIs Robbins basic pathology 9th edition chapter 5 pageno. 202', 'role': 'assistant'}]