This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Medicine
[{'content': 'Treatment of lithium Induced diabetes Insipidus - \nSelect and explain. \nA. Vasopressin, B. Mineralocoicoid antagonist, C. Amiloride, D. Loop diuretic', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans is option 3- amiloride Amiloride is currently the treatment of choice for polyuria in lithium induced diabetic insipidus. Amiloride a potassium sparing diuretic is the drug and raise maximum urinary osmolality in lithium treated patients. It blocks the cellular uptake of lithium ENaC. Thus antogonizing the inhibitory effects of lithium on Vasopressin induced water transpo. Ref Harrison 19 /304', 'role': 'assistant'}]