This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Bony dysplasia and soft tissue affection, Subject name: Orthopaedics
[{'content': 'Blue sclera is feature of - \nSelect and explain. \nA. Osteogenesis imperfecta, B. Osteopetrosis, C. Cleidocranial dysostosis, D. Achendroplasia', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Osteogenesis imperfecta also known as Fragilitas ossium/ Vrolick&;s disease characterised by, Fragility of bones, deafness, Blue sclera, laxity of joints and tendency to improve with age. It results from defective collagen synthesis and thus affects other collagen containing soft tissues such as the skin, sclera, teeth, ligaments etc. Reference - TB of ohopaedics- Ebnezar-3rd edn-pg no 464', 'role': 'assistant'}]