This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pharmacology
[{'content': 'Wof is a limiting adverse effect of ACE inhibitors \nSelect and explain. \nA. Acidosis, B. Hypernatremia, C. Hypokalemia, D. Hyperkalemia', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Adverse effects:- By reducing aldosterone levels, ACE inhibitors decrease K + excretion in the distal nephron leading to hyperkalemia. Hyperkalaemia: more likely in patients with impaired renal function and in those taking K+ sparing diuretics, NSAIDs. Ref:- kd tripathi; pg num:-495,502', 'role': 'assistant'}]