This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Basics of DNA, Subject name: Biochemistry
[{'content': 'Which one of the following statements about chromatin is not true? \nSelect and explain. \nA. DNA winds approximately 1.75 times around the nucleosomes, B. H2A-H2B bind to both the entry and exit ends of DNA in nucleosomes, C. Covalent modification of histones influence chromatin compaction, D. Non-histone proteins are pa of mitotic chromosomes', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Histones The ~145 bp of DNA, consisting of 1.75 superhelical turns, are in contact with the histone octamer Phosphorylation of histone H1 is associated with the condensation of chromosomes and acetylation of core histones is associated with chromosomal assembly Mitotic chromosomes contain scaffold proteins which are non-histone proteins In nucleosomes, entry of DNA is bound by H2A-H2B histones, exit end is bound by H1 histones.', 'role': 'assistant'}]