This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
[{'content': 'Retinoblastoma is associated with- \nSelect and explain. \nA. Osteosarcoma, B. Hepatocellular, C. SCC, D. Osteoclastoma', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Robbins basic pathology 9th edition page no 777 Pathogenesis Several mutations are associated with the devolopmeny of osteosarcoma. The patients with hereditory retinoblastomas have a thousand fold greater risk for devolopment of osteosarcoma.', 'role': 'assistant'}]