This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.V.S, Subject name: Pharmacology
[{'content': 'An anti-arrhythmic drug that is not proarrhythmic? \nSelect and explain. \nA. Lignocaine, B. Disopyramide, C. Amiodarone, D. Moricizine', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. a (Lignocaine). (Ref. KD Tripathi, Pharmacology, 6th /513)# Most anti-arrhythmic can themselves precipitate serious arrhythmias i.e., they have arrhythmogenic potential, hence called proarrhythmic.- Encainide, flecainide, moricizine have higher incidence of sudden death.# Terfenadine, astemizole, cisapride and halofantrine prolong QT interval; co-admin of class la drugs (Quinidine, procainamide, disopyramide, moricizine) or sotalol carries high risk of Torsade de Pointes.Lignocaine has minimal effect on normal ECG and it has no significant autonomic action.', 'role': 'assistant'}]