This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nephropathy, Subject name: Pediatrics
[{'content': 'Mutation in NPHS 1 gene causes which disease? \nSelect and explain. \nA. Alport syndrome, B. Congenital Finnish type nephrotic syndrome, C. Focal segmental glomerulonephritis, D. Nail patella syndrome', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans. (b) Congenital Finnish type nephrotic syndromeRef: Nelson 18th ed./ Table 527.1* CNF is one of the Finnish heritage diseases and rare form of nephrotic syndrome.* It occurs predominantly in families of Finnish origin and manifests shortly after birth* The condition is caused by a defect in the protein nephrin, which is found in the kidney.* Gene responsible is NPHSL.', 'role': 'assistant'}]