This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Epidemiology, Subject name: Social & Preventive Medicine
[{'content': 'In a case controlled study. It is found that the disease is more common in the group taking coffee as compared to the control group. The significance of this is- \nSelect and explain. \nA. Cause and effect relationship established, B. Disease median can be calculated, C. Caffeine is associated with occurrence of disease, D. Controls will not get the disease', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Case-control studies basically comparison study. Cases and control must be comparable with respect to known "confounding factor "such as age , sex occupation, social status, etc. The questions asked relate to personal characteristics and antecedent exposures which may be responsible for the condition studied.', 'role': 'assistant'}]