This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Pathology
[{'content': 'Sideroblast seen in- \nSelect and explain. \nA. Thalassemia, B. Myelofibrosis, C. Alcoholism, D. Iron overload', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Sideroblasts are nucleated erythroblasts with granules of iron accumulated in mitochondria surrounding nucleus.Ring sideroblasts, iron laden mitochondria form 1/3rd or more of nucleus are seen in myelofibrosis.In thalassemia, microcytic hypochromic anisopoikilocytosis are seen .In alcoholism,there is folate deficiency as ethanol inhibits absorption of folate.In iron overload,absence of hepcidin leads to hyperabsorption of iron Ref. Hoffbrand hematology,6th, pg: 47. Robbins and Cotran Pathologic basis of disease,pg:640]', 'role': 'assistant'}]