This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'Treatment of choice in intracran al ALL is: \nSelect and explain. \nA. A. Intrathecal methotrexate, B. Vincristine and prednisolone, C. Intrathecal vincristine, D. Prednisolone', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Answer is A (Intrathecal methotrexate) Intrathecal ,methotrexate is the chemotherapy of choice for intracranial manifestation of Acute Leukemia Treatment of choice for intracranial ALL Combination of intrathecal methotrexate and cranial irradiation. Agents used for Intrathecal chemotherapy Methotrexate Cytarabine Thiotepa Note: Intrathecal Cytarabine may be as effective as intrathecal methotrexate', 'role': 'assistant'}]