This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'If chymotrypsin molecule undergoes a ser-195-ala mutation then : \nSelect and explain. \nA. Chymotrypsin will not bind the substrate, B. Chymotrypsin will bind the substrate as well as cause cleavage, C. Chymotrypsin will bind the substrate but will not cause cleavage, D. No affect will be observed', 'role': 'user'}, {'content': "Answer: C \nExplanation: Serine- 195 is a highly reactive residue of chymotrypsin molecule.It endows chymotrypsin with its 'Reactivity' and not its ability to bind to substrate. In absence of Ser- 195 residue, chymotrypsin is inactivated i.e., it will not cleave, however, it still has the ability to bind (by viue of other remaining residues).", 'role': 'assistant'}]