This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Extended-spectrum beta-lactamases (ESBLs) are characterized by activity against all except : \nSelect and explain. \nA. Penicillinases, B. Cephalosporinases, C. Oxyimino–cephalosporinases, D. Carbapenems', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Carbapenems like imipenem are the only beta-lactams reliably efficacious against ESBL producing bacteria.', 'role': 'assistant'}]