This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Alirocumab and Evolocumab are: \nSelect and explain. \nA. NPGL1 inhibitors, B. Microsomal transport protein inhibitors, C. PCSK - 9 inhibitors, D. Lipoprotein lipase inhibitors', 'role': 'user'}, {'content': 'Answer: C \nExplanation: PCSK - 9 expressed over many tissues which inhibits metabolism of LDL - receptors. Drugs like Alirocumab & Evolocumab inhibit PCSK - 9 and increased LDL - receptor turnover. Thus they decrease the levels of LDL.', 'role': 'assistant'}]