This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Inflammation & Repair, Subject name: Pathology
[{'content': 'The process by which leukocytes are arranged along the endothelium is called: \nSelect and explain. \nA. Margination, B. Rolling, C. Diapedesis, D. Chemotaxis', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans: a (Margination) Ref: Robbins, 7th ed, p.The sequence of events of leukocyte journey from vessel lumen to interstitial tissue is divided into the following steps.a) Margination: leukocyte accumulation along endothelial surface.b) Rolling: Tumbling of leukocyte along the endothelium with transient adherence.c) Adhesion: Attachment with the help of selectins & integrins.d) Diapedesis: Transmigration across the endotheliume) Migration: To a chemotactic stimulusEndothelial/Leukocyte adhesion moleculesEndotheliumLeucocyteMajor functionP. selectinSialyl Lewis XRollingE. selectinSialyl Lewis XRolling, adhesionICAM 1LFA1, MAC1AdhesionVC AM 1VLA4, LPAM1AdhesionCD31 (PECAM)CD31LeucocytetransmigrationGLYCAM 1, CD 34L selectinLymphocyte homing', 'role': 'assistant'}]