This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Bone Tumour, Subject name: Orthopaedics
[{'content': 'Regarding multiple myeloma which of the following statements is wrong: \nSelect and explain. \nA. Malignant neoplasm derived from plasma cells, B. Multiple punched out lesions on radiograms of the skull, C. Multiple hot spots on bone scan, D. Melphalan is used in treatment.', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans. C. Multiple hot spots on bone scana. In Multiple Myeloma, On X-ray lytic lesions are seen. Bone scan is normal. Level of alkaline phosphate in the blood is normal, (despite extensive bone involvement). Generalize body pain is the commonest presentation.b. Hypercalcemia, raised ESR, Anemia, are the features. Raised (b2 micro globulin is a poor prognostic feature.', 'role': 'assistant'}]