This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'Which of the following drugs for moderate-to-severe psoriasis inhibits both IL-12 and IL23? \nSelect and explain. \nA. Alefacept, B. Efalizumab, C. Ustekinumab, D. Abatacept', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Alefacept is anti CD-2 for psoriasis\nEfalizumab is anti CD-11a for psoriasis\nUstekinumab targets the p40 subunit of both IL-12 and IL-23 in psoriasis\nAbatacept is anti CD-80 and CD-86 for severe RA', 'role': 'assistant'}]