This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Medicine
[{'content': 'Anemia in chronic renal failure (CRF) is due to - \nSelect and explain. \nA. Decreased erythropoietin production, B. Iron deficiency, C. Hypoplastic bone marrow, D. Decreased Vit - B12', 'role': 'user'}, {'content': 'Answer: A \nExplanation: <p>Erythropoietic activity in the body is regulated by erythropoietin.The principle site of production of erythropoietin is the kidney .Decreased production of erythropoietin by diseased kidney in chronic renal failure results in decline in erythropoiesis & anemia.</p><p>Reference :Harsh mohan textbook of pathology sixth edition pg no 655.</p>', 'role': 'assistant'}]