This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Pediatrics
[{'content': 'Most common cause of nephrotic syndrome in paediatric age group is \nSelect and explain. \nA. Minimal change disease, B. Membranous glomerulonephritis, C. Malarial infection, D. Mesangioproliferative glomerulonephritis', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. a (Minimal change disease). Refer to Q. No.49 of Pathology section of same paper.Minimal-Change Disease (Lipoid Nephrosis)# This relatively benign disorder is the most frequent cause of the nephrotic syndrome in children.# It is characterized by glomeruli that have a normal appearance by light microscopy but show diffuse effacement of podocyte foot processes when viewed with the electron microscope.# Although it may develop at any age, this condition is most common between ages 1 and 7 years.# When the changes in the podocytes reverse (e.g., in response to corticosteroids), the proteinuria remits.', 'role': 'assistant'}]