This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Medicine
[{'content': '1718. A patient presents with increased serum ferritin, decreased TIBC, increased serum iron, % saturation increased. Most probable diagnosis is - \nSelect and explain. \nA. Anemia of chronic disease, B. Sideroblastic anemia, C. Iron deficiency anemia, D. Thalassemia minor', 'role': 'user'}, {'content': 'Answer: B \nExplanation: In the given case,serum iron is raised,which implies that it is not a iron deficiency anemia or anemia of chronic disorder(where serum iron is reduced) In sideroblastic anemia , serum ferritin levels are raised,marrow iron stores are raised,serum iron is usually raised with almost complete saturation of TIBC. The disorder has its pathogenesis in disturbed growth & maturation of erythroid precursors at the level of hematopoietic stem cell,probably due to reduced activity of the enzyme,ALA synthetase. Reference :Harsh mohan textbook of pathology sixth edition pg no 300.', 'role': 'assistant'}]