This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': "Curschmann's crystals are seen in - \nSelect and explain. \nA. Bronchial asthma, B. Bronchiectasis, C. Chronic bronchitis, D. Wegener's granulomatosis", 'role': 'user'}, {'content': 'Answer: A \nExplanation: Pathology of Asthma\nGross -\n\nLungs are overdistended because of overinflation and there may be a small area of atelectasis.\nThe most striking macroscopic finding is occlusion of bronchi and bronchioles by thick tenacious mucus plugs.\n\nHistology -\n\nCharacterized by the presence of numerous eosinophils and neutrophils.\n\nCurschmann\'s spiral - Whorls of shed epithelium in mucous plugs.\nCharcot -Leyden crystals - Collection of crystalloids made up of eosinophilic membrane protein.\nThe other characteristic histological finding of Asthma is collectively called Airway remodelling, it includes -\n\nThickening of the basement membrane of the bronchial epithelium.\nEdema and an inflammatory infiltrate in the bronchial walls with a prominence of eosinophils and mast cells.\nAn increase in the size of submucosal glands.\nHypertrophy of bronchial wall muscle.\n\nThe "airway remodelling" contributes to airflow obstruction.', 'role': 'assistant'}]