This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Blood disorder, Subject name: Pathology
[{'content': 'A newborn with ABO incompatibility, the characteristic feature on peripheral smear is the presence of: \nSelect and explain. \nA. Microspherocytes, B. Fragmented RBC, C. Polychromasia, D. Elliptocytosis', 'role': 'user'}, {'content': 'Answer: A \nExplanation: In ABO hemolytic disease of newborn -Peripheral blood smear shows numerous spherocytes (predominate) , occasional nucleated red cells, anisocytosis and polychromasia. -The blood film in ABO hemolytic disease of the newborn (ABO HDN) is marked by the presence of microspherocytes. -The spherocytosis is attributed to loss of membrane surface area when the spleen removes antigen-antibody complexes from the affected cell.', 'role': 'assistant'}]