This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Physiology
[{'content': 'A 35 yr old woman presents with swelling of the small joints of the hands. On examination, swan neck deformity is present. Labs show elevated RA factor levels and high anti-CCP levels. She diagnosed with rheumatoid ahritis and staed on steroids for a sho duration. What is the mechanism by which steroids reduce inflammation? \nSelect and explain. \nA. Inhibition of phospholipase A2, B. Inhibition of cyclo-oxygenase, C. | activity of lipoprotein lipase, D. Inhibition of lipogenase', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Steroids reduce inflammation by: Inhibiting phopholipase A2, the precursor of arachdonic acid. Arachidonic acid is the precursor for prostagladins and leukotrienes, which inhibits phospholipase A2. Inhibit the production of interleukin-2 (IL-2) and proliferation A2. Inhibit the release of histamine and serotonin from mast cells and platelets. Ref: Guyton and Hall 13th edition Pgno: 975', 'role': 'assistant'}]