This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Sirolimus is more likely than cyclosporine to cause : \nSelect and explain. \nA. Hypertension, B. Osteoporosis, C. Renal insufficiency, D. Thrombocytopenia', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Cyclosporine and tacrolimus cause nephrotoxicity as an adverse effect.\nSirolimus (rapamycin) results in bone marrow suppression and thus may cause anemia, thrombocytopenia and leu\xadkopenia.', 'role': 'assistant'}]