This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'Most severe form of hereditary spherocytosis is caused by the mutation of: \nSelect and explain. \nA. Ankyrin, B. Alpha spectrin, C. Beta spectrin, D. Band 3', 'role': 'user'}, {'content': 'Answer: B \nExplanation: (Refer: Robbins Pathologic Basis of Disease, 8thedition, pg no: 640-641)\nCommon Gene Mutations in Hereditary Spherocytosis', 'role': 'assistant'}]