This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'A female presents with a history of progressive breathlessness. Histology shows heterogeneous patchy fibrosis with several fibroblastic foci. The most likely diagnosis is - \nSelect and explain. \nA. Cryptogenic organizing pneumonia, B. Non specific interstitial pneumonia, C. Usual interstitial pneumonia, D. Desquamative interstitial pneumonia', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Presence of heterogeneous, patchy fibrosis with fibroblastic foci is characteristic of usual interstitial pneumonia (a\xa0type of idiopathic interstitial pneumonia).\n\nIdiopathic interstitial pneumonia (Idiopathic interstitial lung disease) \n\nIdiopathic interstitial pneumonias (IIP) comprise a group of diffuse parenchymal lung diseases characterized by various degree of inflammation and fibrosis leading to the destruction of lung architecture.\nThe primary area of damage involves interstitium, but other areas become involved as the disease progresses.\nIdiopathic denotes an unknown etiology; therefore known causes must be excluded by Careful history and examinations.\nAll IIPs share similar clinical and radiological features and are distinguished primarily by the histopathological pattern on lung biopsy.', 'role': 'assistant'}]