This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: JIPMER 2019, Subject name: Medicine
[{'content': 'Preferred insulin regimen during pregnancy? \nSelect and explain. \nA. Insulin Regular + NPH, B. Insulin NPH + Lispro, C. Insulin Degludec, D. Insulin Lispro + Insulin regular', 'role': 'user'}, {'content': 'Answer: B \nExplanation: For basalinsulincoverage, intermediate-acting neutralprotamineHagedorn (NPH)insulinhas historically been considered first-line therapy and has been widely studied in this patient population. For postprandial glycemic control, rapid-actinginsulinanalogues, such asinsulinlispro andinsulin aspa, do not cross the placenta and have been safely used in pregnancy.', 'role': 'assistant'}]