This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'Antidote in Atropine poisoning is - \nSelect and explain. \nA. Flumazenil, B. Physostigmine, C. Naloxone, D. NaHCO3', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., Physostigmine o Atropine blocks cholinergic receptors. o So, for atropine overdose, we require a drug that increases cholinergic action, o Physostigmine increases the concentration of Ach. o Physostigmine counteracts central (because it crosses BBB) as well as peripheral symptoms of atropine toxicity (other anticholinesterases like neostigmine and pyridostigmine counteract only peripheral symptoms as they cannot cross BBB) - Physostigmine is the DOC.", 'role': 'assistant'}]