This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunology, Subject name: Microbiology
[{'content': 'In type I hypersensitivity, the mediators is \nSelect and explain. \nA. IgE, B. IgG, C. IgM, D. IgC', 'role': 'user'}, {'content': "Answer: A \nExplanation: (IgE) (161-AN 7th) (202-206-CP)Types of hypersensitivity reactions and their featuresType of reactionClinical syndromeMediatorsType I: IgE1. Anaphylaxis2. Atopy P. K. reactionIgE, histamine and other pharmacological agentsType II: Cytolytic and CytotoxicAntibody-mediated damage- thrombocytopenia-agranulocytosis, hemolytic anemiaIgG: IgM, CType III: Immune complex1. Arthrus reaction2. Serum sickness3. Glomerulonephritis, rheumatic fever and rheumatoid arthritisIgG: IgM C Leucocytes.Type IV: Delayed hypersensitivity1. Tuberculin test - Lepromin test, Frei-test, Histoplasmin and toxoplasmin tests viral infections such as herpes simplex and mumps2. Contact dermatitis - drugs, metal (Nickle, chromium), chemicals3. Granulomatous type TB, Leprosy, Schistosomiasis, sarcoidosis and Crohn's diseaseT. cells, Lymphokines, macrophages", 'role': 'assistant'}]