This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: TB of the Spine, Subject name: Orthopaedics
[{'content': 'What causes both destruction of bone and reduction of joint space? \nSelect and explain. \nA. Tuberculosis, B. Metastasis, C. Multiple myeloma, D. Lymphoma', 'role': 'user'}, {'content': 'Answer: A \nExplanation: (a)TB in spine involves- 2 Vertebra (Bone) + Disk (Cartilage)- Paradiscal- Anterior (to spinal cord)Note: Involvement of posterior elements and single vertebra is relatively rare in TB.', 'role': 'assistant'}]