This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Autoimmune Diseases, Subject name: Pathology
[{'content': 'Most specific antibody in SLE is - \nSelect and explain. \nA. Anti nuclear, B. Anti Sm, C. Anti Ro, D. Anti histone', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., Anti Sm Auto anti bodies in Systemic Lupus Erythematosuso Antinuclear antibody-best screening test.o Anti DS DNA antibody-Specific for SLE only in high litres.o Anti Smantbody-Specific for SLE.o Anti Ro (SS - A) antibody-Predisposes to Sicca syndrome, subacute cutaneous lupus and neonatal lupus with congenital heart block.o Anti histone antibody-Associated with drug induced lupus.", 'role': 'assistant'}]