This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pharmacology
[{'content': 'Carbonic anhydrase inhibitors should not be given in \nSelect and explain. \nA. Sulfonamide hypersensitivity, B. Glaucoma, C. High altitude sickness, D. Metabolic acidosis', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Carbonic anhydrase inhibitors(CAIs)are more likely to produce acidosis in patients of COPD,CRF and DM.They are contraindicated in COPD as they may precipitate respiratory acidosis. They are sulfonamides in structure,so should not be given in hypeensitive persons.', 'role': 'assistant'}]