This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Medicine
[{'content': 'The earlies antibody marker to appear In the serum in Hepatitis B virus infection Is- \nSelect and explain. \nA. Anti-HBs, B. Anti-HBe, C. Anti-HBc, D. Anti-Hbx', 'role': 'user'}, {'content': 'Answer: C \nExplanation: <P>Davidson&;s principles and practice of medicine 22nd edition. #HBc Ag is not found in blood but antibody to it appeared early in the illness (incubation period) and rapidly reached a high titre which subsides gradually but then persist.</p>', 'role': 'assistant'}]