This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Virology (RNA Virus Pa-1,2 & Miscellaneous Viruses), Subject name: Microbiology
[{'content': 'All of the following is/are true about Rubella in pregnancy except \nSelect and explain. \nA. Diagnosed when IgM antibodies are present in the neonatal serum, B. Diagnosed when IgG antibodies persist for more than 6 months, C. Most common defects are cataracts, deafness and hea defects, D. Maternal infection after 16 weeks of gestation result in major congenital defects', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Maternal infection after 16 weeks of gestation result in major congenital defects is not true. Timing of fetal infection determines the extent of teratogenic effect in fetus: Ist 2 months Abnormalities in 65-85% cases, Multiple congenital defects (cataracts, deafness and hea defects) Spontaneous aboion 3rd month of fetal life: 30% to 35% chance of developing a single defect, Deafness ,CHD. During the 4th month 10% risk for a single congenital defect Beyond the 4th month No risk to fetus The classic triad of congenital Rubella includes - Deafness Cataract Congenital hea disease (PDA and PS)', 'role': 'assistant'}]