This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anaesthesia Q Bank, Subject name: Anaesthesia
[{'content': 'Which of the following circumstances trigger non invasive to invasive ventilation \nSelect and explain. \nA. Respiratory arrest, B. RR > 35 /min, C. Sev acidosis < 7.25, D. All of the above', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Circumstances in which non invasive positive pressure ventilation should be changed to invasive ventilation Resp arrest Rr > 35/min Sev dyspnea with use of accessory muscles and possibly paradoxical breathing Life threatening hypoxemia PaO2 <40 mm hg Or PaO2/FiO2 <200 Sev acidosis (pH <7.25 ) and hyperapnia (PaCO2 >60 mm hg ) Hypersomnolence , impaired mental status Cardiovascular complication Failure of non invasive positive pressure ventilation Other circumstances (e.g metabolic abnormalities ,sepsis , pneumonia , pulmonary embolism , barotrauma, massive pleural effusion )', 'role': 'assistant'}]