This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Medicine
[{'content': 'All of the following are seen in active chronic hepatitis B except - \nSelect and explain. \nA. IgM against core antigen, B. Total core antibody, C. HbeAg, D. HbsAg', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Hepatitis B core antigen Hepatitis B core antigen (HBcAg) is not found in the blood, but antibody to it (anti-HBc) appears early in the illness and rapidly reaches a high titre, which subsides gradually but then persists. Anti-HBc is initially of IgM type, with IgG antibody appearing later. Anti-HBc (IgM) can sometimes reveal an acute HBV infection when the HBsAg has disappeared and before anti-HBs has developed . Ref Davidson edition23rd pg874', 'role': 'assistant'}]