This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'Histological appearance of scleroderma include all except \nSelect and explain. \nA. Extensive fibrosis of upper 1/3 of the dermis, B. Decreased adnexal structure., C. Homogenization of collagen, D. Increased dermis thickness', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans: A Extensive fibrosis of upper 1/3 of the dermis Mucin deposition is a feature of metabolic diseases like pretibial myxedema, scleroderma and lichen myxedematosis. Microscopy appearance of scleroderma- Thinning of epidermis, extensive fibrosis of lower 2/3 of dermis, replacement of subcutaneous fat, homogenization of collagen and decreased adnexal structure.', 'role': 'assistant'}]