This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General Pharmacology, Subject name: Pharmacology
[{'content': 'A drug that binds to a receptor at a site distinct from the active site and alters the affinity of the receptor for the endogenous ligand is a: \nSelect and explain. \nA. Competitive antagonist, B. Inverse against, C. Partial agonist, D. Allosteric modulator', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans. d. Allosteric modulatorRef: Goodman Gilman 13th E/P36An allosteric modulator or antagonist is a drug that binds to a site different than target and leads to a decrease affinity of another drug for that target.An allosteric agonist or co-agonist is a drug that binds to a site different than target and leads to an increase affinity of another drug for that target.', 'role': 'assistant'}]