This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Medicine
[{'content': 'Osmotic fragility is increased in - \nSelect and explain. \nA. Sickle cell anaemia, B. Thalassemia, C. Hereditary spherocytosis, D. Chronic lead poisoning', 'role': 'user'}, {'content': 'Answer: C \nExplanation: <p>Osmotic fragility test is helpful in testing the spheroidal nature of red cells which readily lyse more readily in solutions of low salt concentration that is osmotic fagility is increased in hereditary spherocytosis. </p><p>Harsh mohan textbook of pathology 6th edition pg no 315</p>', 'role': 'assistant'}]