This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': "A 2 year old child is brought by parents with history of seizures and developmental delay. He has multiple hypopigmented macules over the back. What is the most probable diagnosis – \nSelect and explain. \nA. Neurofibromatosis type 1, B. Tuberous sclerosis, C. Sturge weber's syndrome, D. Linear Sebaceous nevus syndrome", 'role': 'user'}, {'content': 'Answer: B \nExplanation: History of seizures and multiple hypopigmented macules over the back (ash leap patch) suggest the diagnosis of tuberous sclerosis.\nCriteria for diagnosing tuberous sclerosis \n\nCriteria for diagnosis of tuberous sclerosis complex have been revised.\nThe features have been divided into major features and minor features : -\n\n\nDefinitive diagnosis ---> Either 2 major features or 1 major plus 2 minor features.\nProbable diagnosis --> 1 Major plus 1 minor features\nPossible diagnosis\xa0\xa0\xa0\xa0\xa0\xa0-->\xa0\xa0\xa0\xa0\xa0\xa0\xa0 1 Major feature or 2 or more minor features', 'role': 'assistant'}]