This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
[{'content': 'Kaposi sarcoma is commonly seen in - \nSelect and explain. \nA. Upper limbs, B. Lower limbs, C. Head and Neck, D. Trunk', 'role': 'user'}, {'content': 'Answer: B \nExplanation: • DFSP is a low-grade sarcoma because it may recur locally but rarely metastasizes.\n• Monomorphous, mononuclear, spindle cell lesion involving both dermis and subcutis.\n• MC site: Trunk\xa0(50%) >Extremities (30%) >Head and neck (20%)\nPathology\n• Large lesions often are associated with satellite nodules; Positive for CD34\n• Have unpredictable radial extensions\xa0of tumor permeating through the subcutaneous tissue large distances from the primary nodule.\n• More than 75% of DFSP have a ring chromosome, composed of translocated portions of chromosomes 17 and 22\nClinical Features\n• Typically presents in early or mid-adult life, beginning as a nodular cutaneous mass.\n• Pattern of growth: Slow and persistent\n• Lesion enlarges over many years, it becomes protuberant\nTreatment\n• Aggressive resection with special attention to radial margins (local recurrence rate <5%)\n• Up to 50% recur after simple excision.\n• Imatinib: First line of treatment for advanced disease.', 'role': 'assistant'}]