This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetics, Subject name: Pathology
[{'content': 'Karyotyping is done in which phase of cell cycle: \nSelect and explain. \nA. Anaphase, B. Metaphase, C. Telophase, D. S phase', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans. (b) Metaphase(Ref: Robbins 9th/pg 158; 8th/pg 159)In KaryotypeChromosomes are examined after arresting dividing cells in metaphase with mitotic spindle inhibitors (e.g. N-diacetyl-N-methylcolchicine), followed by stainingResolution of Karyotyping: 2 to 5 million base pairs Q', 'role': 'assistant'}]