This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Maintenance dose depends on ? \nSelect and explain. \nA. Clearance, B. Volume of distribution, C. Metabolism, D. Absorption', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Clearance o Loading dose is governed by volume of distribution. o Maintenance dose is governed by clearance or t1/2.", 'role': 'assistant'}]