This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anaesthesia, Subject name: Pharmacology
[{'content': 'A patient receives a toxic dose of lignocaine i.v., the patient is likely to exhibit? \nSelect and explain. \nA. Excessive salivation, B. Mydriasis and diarrhea, C. Respiratory paralysis, D. Seizures and coma', 'role': 'user'}, {'content': 'Answer: D \nExplanation: * If LA reaches the blood stream, most prominent adverse effects are related to CNS and CVS. * In CNS :-stimulation (convulsions) followed by depression (coma) is seen. - Initial stimulation is due to inhibition of the inhibitory neurons.', 'role': 'assistant'}]