This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Sickle Cell Disease, G6PD deficiency and other Hemolytic Anemia, Subject name: Medicine
[{'content': 'X-ray skull characteristically shows "Hair on end"appearance in which of the following disease? \nSelect and explain. \nA. Still\'s disease, B. Scurvy, C. Neuroblastoma, D. Cirrhosis of liver', 'role': 'user'}, {'content': 'Answer: C \nExplanation: The hair on end sign refers to a radiographic appearance on skull which results from a periosteal reaction manifesting as perpendicular trabeculations interspersed by radiolucent marrow hyperplasia along the skull vault. Mnemonic: H.I.N.E.S.T Hereditary spherocytosis Iron deficiency Anemia Neuroblastoma Enzyme deficiency (e.g. G-6-P deficiency causing Hemolytic Anemia) Sickle cell disease Thalassemia major', 'role': 'assistant'}]