This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'A 20 years old boy with known history of mental illness was brought to emergency room with aggressive behaviour and tendency to attack others physically. After psychiatric evaluation, he was prescribed some new drugs and dose of previous drugs changed. After 3 days, he presents to emergency room again with fever (1050C), stiff limbs, altered sensorium and elevated serum CPK levels. What is the immediate management for this condition? \nSelect and explain. \nA. Succinyl choline, B. Dantrolene, C. Edrophonium, D. Neostigmine', 'role': 'user'}, {'content': "Answer: B \nExplanation: (Refer: Kaplan & Sadock's CTP, 10th Ed Chap 34.17\xa0 P.7849)\nNeuroleptic malignant syndrome\n\nA rare but extremely serious complication of neuroleptic treatment especially with high potency compounds. Evolve over 24-72 hours untreated last for 10 to 14 days , even fatal\nClinical features\n\t\nHyperthermia\nMuscular rigidity – Increased muscle tone, dysphagia, dysponea\nAutonomic disturbance – Elevated BP, HR, salivation, incontinence of urine\n\n\nRaised WBC and creatinine phosphokinase\nManagement\n\t\nDiscontinuation of all medications\nHyperventilate with 100% oxygen\nAdminister sodium bicarbonate 1 – 2 mEq/kg IV and dantrolene sodium 2.5 mg/kg IV\nAdminister inotropes, anti-arrhythmic agents\nMonitor urinary output, K+, Ca2+, blood gases, end tidal carbon dioxide\nConsider invasive monitoring of arterial blood pressure and central venous pressure\nCorrection of acidosis and control of temperature.", 'role': 'assistant'}]