This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Most common cause of death in primary am loidosis is? \nSelect and explain. \nA. Respiratory failure, B. Cardiac failure, C. Renal failure, D. Septicemia', 'role': 'user'}, {'content': "Answer: B \nExplanation: Cardiac failure REF: Harrison's Internal Medicine 17th edition chapter 324. Amyloidosis The kidneys are the most frequently affected organ (80%). Renal amyloidosis is usually manifested by proteinuria, which is often in the nephrotic range and associated with significant hypoalbuminemia and edema or anasarca; rarely, tubular rather than glomerular deposition of amyloid can produce azotemia without significant proteinuria. Cardiac symptoms are the second most common presentation (40%), but cardiac dysfunction is associated with death in 75% of patients.", 'role': 'assistant'}]