This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Clostridium, Subject name: Microbiology
[{'content': 'Tetanus spasm occurs due to which of the following toxin: \nSelect and explain. \nA. Tetanotysin, B. Lecithinase, C. Neurotoxin, D. Tetanospasmin', 'role': 'user'}, {'content': "Answer: D \nExplanation: Am: d (telanospasmin)Ref: Ananthanarayan and Paniker's Textbook of Microbiology, 801 edi., Pg. 257-260TetanusClostridium tetani is a gram positive spore bearing bacilli with drum stick appearance.It swarms over agar surface.Three important toxins of cl. Tetani are:- Tetanolysin - heat & oxygen labile haemolysin, not relevant in pathogenesis- Tetanospamin - responsible for tetanus, oxygen stable but heat labile, plasmid coded and toxoided- Neurotoxin - peripherally active, non spasmogenic Tetanospasmin blocks synaptic inhibition of spinal cord esp GABA & giycine which causes uncontrolled spread of impulses- muscle rigidity and spasm --with tonic extension of body.", 'role': 'assistant'}]