This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Breast, Subject name: Surgery
[{'content': 'All of the following are poor prognostic markers of CA Breast except- \nSelect and explain. \nA. DNA aneuploidy, B. ER positivity, C. Her 2 neu positivity, D. p53 over expression', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans. (b) ER positivity(Ref Schwartz 10th edition page 536)Poor Prognostic factors of Breast Cancer:Tumor related factorsHost related factors* Nodal status - Increased* Size and Grade of tumor - High* Lympho vascular invasion* Hormone Receptor- Negative* High Pathological staging* DNA Ploidy, S Phase fraction +* Her 2/neu overexpression* Intraductal component+* Young age* Menopausal status* Family History* Breast cancer History* Nutrition* Prior Chemotherapy and RT', 'role': 'assistant'}]