This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Norepinephrine to epinephrine conversion requires which enzyme: \nSelect and explain. \nA. Phenylethanolamine-N-methyltransferase, B. Transaldolase, C. Tyrosine hydroxylase, D. Alpha ketoglutarate', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans:A.)Phenylethanolamine-N-methyltransferaseMethylation of norepinephrine by S-adenosyl-methionine gives epinephrine, reaction being catalysed by phenylethanolamine N-methyltransferase Phenylethanolamine N-methyltransferase (PNMT)It is an enzyme found in the adrenal medulla that conves Norepinephrine (Noradrenaline) to Epinephrine (Adrenaline).PNMT is positively influenced by coisol, which is produced in the adrenal coex.S-adenosyl-L-methionine ('SAM') is a required cofactor.", 'role': 'assistant'}]