This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Misc., Subject name: Physiology
[{'content': 'Regarding brown adipose tissue false is \nSelect and explain. \nA. High ATP synthase activity, B. High vascularity, C. Reduced or absent in the obese, D. High content of mitochondria', 'role': 'user'}, {'content': 'Answer: A \nExplanation: (A) High ATP synthase activity # THERMOGENIN (called uncoupling protein by its discoverers and now known as uncoupling protein 1, or UCP1) is an uncoupling protein found in the mitochondria of brown adipose tissue (BAT). A mitochondrial uncoupling protein (UCP-1) in BAT dissipates the hydrogen ion gradient in the oxidative respiration chain and releases energy as heat. The metabolic activity of BAT is increased by a central action of leptin, acting through the sympathetic nervous system that heavily innervates this tissue.', 'role': 'assistant'}]