This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'True about Budd-chiari syndrome -a)  Associated with coagulopathyb)  Cirrhosis may occur c) Good prognosisd)  Ascites may be present e)  Hepatic vein thrombosis \nSelect and explain. \nA. abcd, B. bcde, C. acde, D. abde', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Budd Chiari syndrome may be predisposed by hypercoagulable conditions, eg\xa0deficiency of antithrombin, protein\xa0C & S.\nClinical features\nThe acute syndrome presents with rapidly progressive - severe upper abdominal pain, jaundice, hepatomegaly (enlarge liver), ascites, elevated liver enzymes and eventual encephalopathy.\nThe fulminant syndrome presents early with encephalopathy and ascites. Severe hepatic necrosis and lactic acidosis may be present as well. Caudate lobe hypertrophy is often present. The majority of patients have a slower-onset form of Budd-chiari syndrome. A system of venous collaterals may form around the occlusion which may be seen on imaging as a "spider\'s web". Patients may progress to cirrhosis and show signs of liver failure.\nAn asymptomatic form may be totally silent and discovered only incidently. It is generally not concerning.\nPrognosis\nSeveral studies have attempted to predict the survival of patients with Budd-chiari syndrome.\nIn general, nearly 2/3 of patients with Budd- chiari are alive at 10 years.\nImportant negative prognostic indicators include ascites, encephalopathy, elevated Child-Pugh scores, elevated prothrombin time and altered serum levels of various substance(sodium, creatinine, albumin and bilirubin).\nSurvival is also highly dependent on the underlying cause of the Budd-chiari syndrome, eg\xa0patients with myeloproliferative disorders may progress to acute leukemia independent of Budd-chiari syndrome.', 'role': 'assistant'}]