This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunity, Subject name: Pathology
[{'content': 'Antibody dependant cell mediated toxicity is seen in? \nSelect and explain. \nA. NK cell, B. NK cell only, C. Macrophage, D. NK cells, neutrophils & macrophages', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans. (d) NK cells, neutrophils & macrophagesAntibody-dependent cell-mediated cytotoxicity (ADCC) is the killing of an antibody-coated target cell by a cytotoxic effector cell through a non-phagocytic process, characterised by the release of the content of cytotoxic granules or by the expression of cell death-inducing molecules. ADCC is triggered through interaction of target-bound antibodies (belonging to IgG or IgA or IgE classes) with certain Fc receptors (FcRs), glycoproteins present on the effector cell surface that bind the Fc region of immunoglobulins (Ig). Effector cells that mediate ADCC include natural killer (NK) cells, monocytes, macrophages, neutrophils, eosinophils and dendritic cells', 'role': 'assistant'}]