This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
[{'content': 'Karyotyping can be used to diagnose which of the following disease? \nSelect and explain. \nA. Klinefelter’s syndrome, B. Multiple myeloma, C. Niemann-Pick disease, D. Pemphigus', 'role': 'user'}, {'content': 'Answer: A \nExplanation: The only disease listed that is related to an abnormal number of chromosomes is Klinefelter’s syndrome. This disease is characterized by two or more X chromosomes and one or more Y chromosome. Typically, those affected have 47 chromosomes with a karyotype of XXY.', 'role': 'assistant'}]