This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nervous system, Subject name: Pathology
[{'content': 'A 60-year-old woman has a history of being treated for endometrial cancer with surgery and radiation 5 years ago. She now presents with a large necrotic tumor that follows the course of the sciatic nerve. Which of the following is the most likely diagnosis \nSelect and explain. \nA. Malignant peripheral nerve sheath tumor, B. Solitary neurofibroma, C. Neurofibromatosis type 2, D. Schwannoma', 'role': 'user'}, {'content': 'Answer: A \nExplanation: The development of a necrotic tumor involving a peripheral nerve in an area that was irradiated previously is characteristic of a malignant peripheral nerve sheath tumor. Ref:- Harsha Mohan textbook of Pathology', 'role': 'assistant'}]