This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Structure and function of protein, Subject name: Biochemistry
[{'content': 'Function of Topoisomerases \nSelect and explain. \nA. Deoxynucleotide polymerization, B. Relieve torsional strain, C. Initiates synthesis of RNA primers, D. Prevent premature reannealing of dsDNA', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Classes of Proteins Involved in ReplicationProteinFunctionDNA polymerasesDeoxynucleotide polymerizationHelicasesATP -driven processive unwinding of DNATopoisomerasesRelieve torsional strain that results fromhelicase-induced unwindingDNA primaseInitiates synthesis of RNA primersSingle-strand bindingproteins (SSBs)Prevent premature reannealing of dsDNADNA ligaseSeals the single strand nick between thenascent chain and Okazaki fragments on the lagging strandRef: Harper&;s Biochemistry; 30th edition; Chapter 35; DNA Organization, Replication, & Repair', 'role': 'assistant'}]