This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'Which virus is implicated in Burkits lymphoma? \nSelect and explain. \nA. EBV, B. HTLV, C. HPV, D. HHV8', 'role': 'user'}, {'content': 'Answer: A \nExplanation: (Refer: Robbins Pathologic Basis of Disease, 8thedition, pg no: 314, 607)\nBurkitt’s lymphoma\nThere are three clinical types:\n\nAfrican (endemic) Burkitt lymphoma.\nSporadic (nonendemic) Burkitt lymphoma.\nAggressive lymphomas associated with HIV.\n\tThese 3 types are histologically identical.\n\nImmunophenotype\n\nThese are tumors of mature B cells.\nIt express surface IgM, CD19, CD20, CD10 and BCL6.\n\nMolecular Pathogenesis\n\nAll forms of Burkitt lymphoma are associated with translocationsof the c-MYC gene on chromosome 8.\nThe translocation partner is usually the IgH locus (t(8;14)) butmay also be the Ig k (t(2;8)) or y (t(8;22)) light-chain loci.\nAll endemic tumors are latently infected with EBV, which is alsopresent in about 25% of HIV-associated tumors and 15% to20% of sporadic cases.', 'role': 'assistant'}]