This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'All of the following are true in respect of angioneurotic edema EXCEPT? \nSelect and explain. \nA. It is caused by deficiency of complement proteins, B. It manifests as pitting edema, C. It is more common in females, D. It is an autosomal dominant disorder', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Angio-neurotic edema is a localized non-pitting edema involving deeper layers of the skin and\xa0subcutaneous tissue. It is an autosomal dominant clinical condition caused by a deficiency of Cl inhibitor\xa0protein (a complement regulatory protein) and associated with elevated levels of bradykinin. It is more\xa0common in females\n• Diagnosis of hereditary angioedema is suggested by the presence of lack of pruritus and\xa0urticarial lesions, prominence of recurrent gastrointestinal attacks of colic and episodes of\xa0laryngeal edema. The levels of complement proteins Cl is normal but levels of C2 and C4 are depleted.\n• Danazol is the drug which can be used for hereditary angioedema.', 'role': 'assistant'}]