This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Joint disorders, Subject name: Anatomy
[{'content': 'Which NSAID can cause hyperuricemia? \nSelect and explain. \nA. Tolmetin, B. Ibuprofen, C. Aspirin, D. Naproxen', 'role': 'user'}, {'content': 'Answer: B \nExplanation: ASPIRIN can cause hyperuricemia depending on dose used. At low doses :1-2g/day -decrease uricacid excretion and hence cause hyperuricemia. It also blocks the effects of probencid and other uricosuric drugs. Intermediate doses:2-3g/day-No effect Large doses:>5g/day-uricosuric 1st most commonly used NSAID in hyperurecemia ahritis (gout) is NAPROXONE 2nd most commonly used is IBUPROFEN ref : maheswari th ed', 'role': 'assistant'}]