This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Substance Related and Addictive Disorders, Subject name: Psychiatry
[{'content': "Earliest symptoms showing improvement from the classical triad of Wernicke's encephalopathy to thiamine therapy is: \nSelect and explain. \nA. Ataxia, B. Ophthalmoplegia, C. Confusion, D. All improve simultaneously", 'role': 'user'}, {'content': "Answer: B \nExplanation: Wernicke's encephalopathy - Long term use of alcohol lead to thiamine deficiency . Wernicke encephalopathy, caused by vitamin B1 deficiency, is not diagnosed in about 80% of cases. Classical triad Global confusion Ophthalmoplegia - m/c/c 6th nerve palsy Ataxias After thiamine therapy 1st one to improve is ophthalmoplegia followed by global confusion", 'role': 'assistant'}]