This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Pathology
[{'content': 'Intrinsic causes of hemolytic anemia are all except- \nSelect and explain. \nA. Hypersplenism, B. G6PD deficiency, C. Hereditary spherocytosis, D. Pyruvate kinase deficiency', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Intrinsic causes of hemolytic anemias are due to defective RBCs which includes- Hereditary spherocytosis,Hereditary elliptocytosis, Hmp shunt enzyme deficiency(G6PD deficiency), glycolytic enzyme (pyruvate kinase )deficiency, thalassemia, sickle cell disease . While in hyper splenism RBCs are destroyed by sequestraion which is an extrinsic cause. Ref : Robbins pathologic basis of disease edition :9 pg 630 ; table 14-1', 'role': 'assistant'}]