This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Surgery
[{'content': "Hirschprung&;s disease true are \nSelect and explain. \nA. Sometimes found in adult, B. Dilated segment involved, C. Auerbach's plexus absent, D. Sometimes involve small intestine", 'role': 'user'}, {'content': "Answer: A \nExplanation: .* It is a congenital, familial condition, occurring in newborn due to the absence of ganglion cells--Auerbach's and Meissner's plexus in anorectum, which may extend proximally either a pa or full length of the colon. * It always involves the anus, internal sphincter and rectum (paly or entirely). * There is narrow, spasmodic, non relaxing pathological segment. * Transitional zone proximal to it contains only few ganglion cells with formation of cone. * Still proximal to it, colon is dilated enormously with hyperaemia, multiple ulcers and hyperophied circular muscle fibers. * It is one of the causes of neonatal intestinal obstruction. * Severe enterocolitis can occur which may be fatal. Perforation, peritonitis and septicaemia can occur. * Often there will be a chronic course of the disease with malnutrition, abdominal distension. ref:SRB &;s manual of surgery,ed 3,pg no-818", 'role': 'assistant'}]