This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Clotting factor, Subject name: Pathology
[{'content': 'The use of desmopressin is best indicated for therapy in which of the following bleeding disorders? \nSelect and explain. \nA. Severe hemophilia A, B. Severe hemophilia B, C. Von Willebrand disease (VWD), D. Glanzmann thrombasthenia', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Patients with Von Willebrand disease facing hemostatic challenges (dental work, surgery, etc.) can be treated with desmopressin, which stimulates vWF release, or with infusions of plasma concentrates containing factor VIII and vWF. Hemophilias A and B (severe phenotype) are treated by deficient factor replacement therapy, fresh frozen plasma, etc. Desmopressin can be used in the treatment of mild hemophilia A. Platelet transfusion is the standard treatment for severe bleeding and perioperative hemostasis in patients with Glanzmann thrombasthenia.', 'role': 'assistant'}]