This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: A.N.S., Subject name: Pharmacology
[{'content': 'All of the following agents are used in glaucoma treatment, except. \nSelect and explain. \nA. Apraclonidine, B. Timolol, C. Pilocarpine, D. Metoprolol', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans. (D) Metoprolol(Ref: Katzung 10/e p103, 152; KDT 8th/e p162)Metoprolol is a beta blocker with local anaesthetic activity. Such beta blockers are not indicated in glaucoma.Apraclonidine (alpha 2 agonist), timolol (beta blocker without local anaesthetic activity) and pilocarpine (directly acting miotic) are used in glaucoma.', 'role': 'assistant'}]