This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Salvage pathway of purine biosynthesis is impoant for ? \nSelect and explain. \nA. Liver, B. RBCs, C. Kidney, D. Lung', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Purine nucleotide synthesis occurs by two pathways : 1.De novo synthesis 2.Salvage pathway Liver is the major site of purine nucleotide biosynthesis (de novo). Ceain tissues cannot synthesize purine nucleotides by de novo patyway, e g. brain, erythrocytes and polymorphonuclear leukocytes. These are dependent on salvage pathway for synthesis of purine nucleotides by using exogenous purines, which are formed by degradation of purine nucleotides synthesized in liver.', 'role': 'assistant'}]