This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Bacterial infections, Subject name: Dental
[{'content': 'An infant presents with the condition as shown below after a pharyngeal infection. The shown condition is: \nSelect and explain. \nA. Staphylococcal scalded skin syndrome, B. Epidermolysis bullosa simplex, C. Impetigo contagiosa, D. Pemphigus foliaceus', 'role': 'user'}, {'content': "Answer: A \nExplanation: SSSS/ Pemphigus Neonatorum / Ritter's disease: - Caused by: Staph. aureus - Seen in neonates and infants - Usually follows pharyngeal infection. - Staph. aureus releases Exfoliative toxins A & B that destroys Desmoglein 1 - Mucosal involvement absent - Epidermal separation occurs superficially. - Nikolsky sign positive - when pressure applied tangentially to skin, overlying epidermis will separate. Treatment of SSSS - Usually requires hospitalisation i/v antibiotics are given. A penicillinase-resistant, anti-staphylococcal antibiotic such as flucloxacillin is used. Other antibiotics include nafcillin, oxacillin, cephalosporin and clindamycin.", 'role': 'assistant'}]