This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Biochemistry
[{'content': "Patients with both Graves' disease and Cushing syndrome are overproducing hormones that have which one of the following in common? \nSelect and explain. \nA. Reacting with receptors in the cell membrane, B. Utilizing second messengers, C. Binding to intracellular receptors, D. Binding to RNA to produce physiologically active proteins", 'role': 'user'}, {'content': "Answer: C \nExplanation: Graves' disease is caused by the hypersecretion of thyroid hormone, whereas Cushing syndrome is an overproduction of cortisol. Steroid hormones and thyroid hormones cross the cell membrane and bind to intracellular receptors. The hormone-receptor complex binds to DNA, not RNA. Polypeptide hormones and epinephrine react with the receptors in the cell membrane, triggering second messengers to transmit the signal that the receptor is occupied. Ribosomal RNA (rRNA) does not ablate gene expression; the induction of miRNA has that ability.", 'role': 'assistant'}]