This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Refractory schizophrenia - What is the treatment of choice - \nSelect and explain. \nA. Haloperidol, B. Flupenthixol, C. Trifluoperazine, D. Clozapine', 'role': 'user'}, {'content': "Answer: D \nExplanation: Ans. is 'd' i.e., Clozapine o Clozapine (but not the newer atypicals) is more effective than classical agents for resistant schizophrenia.", 'role': 'assistant'}]