This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy, Subject name: Pharmacology
[{'content': 'Which of the following statement about imipenem is most accurate? \nSelect and explain. \nA. The drug has a narrow spectrum of anti-bacterial action, B. It is used in fixed combination with sulbactam, C. Imipenem is highly susceptible to beta lactamase produced by enterobacteriaciae, D. In renal dysfunction, dosage reduction are necessary to avoid seizures', 'role': 'user'}, {'content': 'Answer: D \nExplanation: lmipenem It is an extremely potent and broad-spectrum', 'role': 'assistant'}]