This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
[{'content': 'True increase in islet cella) Nesidioblastomab) Type II DMc) Insulinomad) Pancreatitis \nSelect and explain. \nA. a, B. ac, C. ad, D. b', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Also known as persistent hyperinsulinemic hypoglycemia of infancy. Characterized by diffuse hyperfunction of pancreatic beta cells with enlargement of their nuclei. Neither the beta cell proliferation rate nor the overall beta cell mass is increased.\nClinical Features\n\nEarly recognition of congenital hyperinsulinism is critical because, if untreated, profound hypoglycemia may lead to brain damage.\nBabies may be described as jittery, floppy, or lethargic; seizures are common.\n\nDiagnosis\n\nInappropriately elevated insulin in the setting of hypoglycemia, along with the need for continuous glucose infusion (<15 mg/kg/min) to maintain normoglycemia confirms the diagnosis.\nPancreatic venous sampling is used to make the diagnosis.\n\nTreatment\n\nContinuous glucose administration with suppression of insulin secretion by diazoxide or somatostatin.\nOperation is necessary in more than two thirds of cases.\nTreatment consists of near total (95-98%) pancreatectomy.', 'role': 'assistant'}]