This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Anatomy
[{'content': 'Which of the following increases the susceptability to corornary aery disease? \nSelect and explain. \nA. Type V hyperlipoprotenemia, B. Von willibrand disease, C. Nephrotic syndrome, D. Systemic lupus erythematosus', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Nephrotic syndrome is a clinical complex characterized by protenuria,hypoalbunemia,edema and hyperlipedemia. A hypercoaguble state frequently accompanied by severe nephrotic syndrome due to urinary loss of AT-III reduced serum levels of protein C and S hyper fibrogenemia and enhanced platelet aggregation. Due to increased coagulation state,predisposing to CAD is present in patients with nephrotic syndrome (ref Harrisons 17th/272)', 'role': 'assistant'}]