This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Autonomic nervous system, Subject name: Pharmacology
[{'content': 'Which of the following antiglaucoma medications are not safe in infants \nSelect and explain. \nA. Timolol, B. brimonidine, C. Latanoprost, D. Dorzolamide', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Apraclonidine and brimonidine can cross blood brain barrier and can cause CNS depression and Apnea in neonates. therefore these are contraindicated in children less than 2 years of age Refer Goodman and Gilman 12e p1788,kdt 6/e 168', 'role': 'assistant'}]