This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Ophthalmology
[{'content': 'Cataract in diabetic patients is because of the accumulation of sorbitol in the lens. The enzyme responsible for this is – \nSelect and explain. \nA. Hexokinase, B. NADPH+ dependant aldolase reductase, C. Glucokinase, D. Phosphofructo isomerase', 'role': 'user'}, {'content': 'Answer: B \nExplanation: NADPH+ dependent aldolase reductase reduces excessive glucose to sorbitol and intracellular accumulation of sorbitol causes osmotic changes resulting in cataract development.', 'role': 'assistant'}]