This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Central Nervous system, Subject name: Pharmacology
[{'content': 'Disulfiraim and acamprosate are used for: \nSelect and explain. \nA. Alcohol abstinence, B. Cocaine abuse, C. Opium poisoning, D. Atropine over dose', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Disulfiram inhibits the enzyme aldehyde dehydrogenase probably after conversion into active metabolite .When alcohol is ingested after taking disulfiram the concentration of acetaldehyde in tissue & blood rises & number of highly distressing symptoms produced. Disulfiram aversion therapy is indicated in abstinent subjects. Ref KD Tripathi 8th ed.', 'role': 'assistant'}]