This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Classical pathway macrophage activating molecule \nSelect and explain. \nA. IFN gamma, B. IL 4, C. IL 13, D. ILI', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Answer- A. IFN gammaThere are two major pathways of macrophage activation:Classical macrophage activation- induced by microbial products, which engage toll like receptors & other sensors, by T cell derived signals, impoantly the cytokine IFN-yAlternative macrophage activation - induced by cytokines III & ILl3 produced by T lymphocytes & other cells. Their main function is tissue repair & secrete growth factors which cause angiogenesis, activate fibroblasts & stimulate collagen synthesis.', 'role': 'assistant'}]