This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetics of Common Disorders, Subject name: Pediatrics
[{'content': "Only males are affected in? \nSelect and explain. \nA. Scheie's syndrome, B. Hunters syndrome, C. Hurlers syndrome, D. Gauchers disease", 'role': 'user'}, {'content': 'Answer: B \nExplanation: Inheritance of: -* Gaucher\'s disease- Autosomal recessive- Affects both males and females* Hurler syndrome- Autosomal recessive- Affects both males and females* Scheie\'s syndrome- Autosomal recessive- Affects both males and females* Hunters syndrome- X linked recessive- Only affect malesMost probably the question should have been, "Only males are affected in"The answer would have been Hunters syndromeAll these are lysosomal storage diseases.Remember that - "All lysosomal diseases are autosomal recessive except for Hunter\'s syndrome and Fabry\'s disease which are X- linked recessive"As hunter\'s syndrome is X-linked recessive, it will affect onl males.', 'role': 'assistant'}]