This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Disorders of Pituitary Gland, Subject name: Pediatrics
[{'content': 'Lesions of which of the hypothalamic nuclei cause diabetes insipidus? \nSelect and explain. \nA. Dorsomedial nuclei, B. Supraoptic and paraventricular nuclei, C. Median preoptic nuclei, D. Ventromedial nuclei', 'role': 'user'}, {'content': 'Answer: B \nExplanation: - Vasopressin, a 9-amino-acid peptide, has both anti-diuretic and vascular pressor activity - It is synthesized in the paraventricular & supraoptic nuclei of the hypothalamus. - Deficiency of Vasopressin causes Diabetes insipidus. - DI results in Polyuria & polydipsia Satiety center Ventromedial nuclei (VMN) Reward centre Medial forebrain bundle Circadian rhythm Suprachiasmatic nucleus Oxytocin Paraventricular nucleus', 'role': 'assistant'}]