This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'A couple, with a fimily history of beta thalassemia major in a distant relative, has come for counseling. The husband has HbA2 of 4.8% and the wife has HbA2 of 2.3%. The risk of having a child with beta thalassemia major is - \nSelect and explain. \nA. 50%, B. 25%, C. 5%, D. 0%', 'role': 'user'}, {'content': "Answer: D \nExplanation: Ans. is 'd' i.e., 0%", 'role': 'assistant'}]