This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Pharmacology
[{'content': 'Which diuretic be considered appropriate for combining with ACE inhibitors? \nSelect and explain. \nA. Spironolactone, B. Eplerenone, C. Hydrochlorothiazide, D. Amiloride', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Thiazides, loop diuretics produce hypokalemia which can be compensated with hyperkalemia produced by ACE inhibitors Potassium-sparing diuretics like spironolactone, eplerenone, amiloride - produce hyperkalemia- so not to be used with ACE inhibitors ( Essentials of medical pharmacology, K.D Tripathi, 6 th edition, page 568 )', 'role': 'assistant'}]