This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Anatomy
[{'content': "Waldenstrom's macroglobulinemia is seen in \nSelect and explain. \nA. NHL, B. Plasmocytic Lymphoma, C. CLL, D. None", 'role': 'user'}, {'content': 'Answer: B \nExplanation: Waldenstrom Macroglobulinemia B cell neoplasm in 6th or 7th decade of life similar to CLL/SLE and multiple myelomaGenetics - Deletion of chromosome 6qNeoplastic infiltrates into organs like spleen, lymph node & bone marrowBalanced production of light and heavy chains thereby decreasing the development of renal failure or amyloidosisBlood - anemia, atypical plasmacytoid lymphocytes, | ESR, rouleaux formation Immunoelectrophoresis - Presence of "M" or monoclonal spikeBone marrow - plasmacytoid infiltrates, PAS + inclusions, Russell bodies ( cytoplasmic Ig), Dutcher bodies ( nuclear Ig )Immunophenotyping - CD 20 +, CD 5- and CD 10-(Refer: Robbins & Cotran\'s - Pathologic Basis of Disease, SAE, 1st edition, Vol I-pg no: 598-599)', 'role': 'assistant'}]