This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Pathology
[{'content': 'Collagen accumulated in space of Disse in case of liver cirrhosis are \nSelect and explain. \nA. 1 and 4, B. 2 and 4, C. 1 and 3, D. 2 and 3', 'role': 'user'}, {'content': 'Answer: C \nExplanation: In the normal liver, ECM consisting of interstitial collagens(fibril forming collagen types I, II, V and XI) is present only in the liver capsule, in poal tracts and around central veins. In cirrhosis, types I and III collagen and other ECM components are deposited in the space of disse. ROBBINS BASIC PATHOLOGY NINTH EDITION PAGE 607', 'role': 'assistant'}]