This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Gastrointestinal tract, Subject name: Pediatrics
[{'content': 'In a child with acute liver failure, the most impoant abnormal serum biochemical test that indicates poor prognosis is ? \nSelect and explain. \nA. Increasing transaminase, B. Increasing bilirubin, C. Increasing prothrombin time, D. Reversal of serum albumin-globulin ratio', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Despite suppoive care and nursing in intensive care 40-70%children with acute liver failure die. poor prognostic markers are grade lll or more hepatic encephalopathy, prothrombin time more than 40 s , presence of sepsis and chest infection. Prothrombin time indicates coagulopathy which is a complication of acute liver failure Ref : ESSENTIAL PEDIATRICS,O.P.GHAI, PG NO:288, 7 th edition', 'role': 'assistant'}]