This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Physiology
[{'content': 'Which of the following is not directly controlled by ACTH? \nSelect and explain. \nA. Glucocoicoids, B. Androstenedione, C. Dehydroepiandrosterone, D. Epinephrine', 'role': 'user'}, {'content': 'Answer: D \nExplanation: THe secretion of the adrenal medullary hormones(epinephrine, norepinephrine and dopamine) is not controlled directly by ACTH. ACTH controls mainly secretion of adrenal coical hormones: Glucoicoids (coisol, coicosterone) and sex steroids (testosterone, DHEA, androstenedione ). Note: The major regulators of aldosterone are angiotensim II and potassium. However, ACTH can also stimulate aldosterone prooduction. Hormones secreted Regulated by Zona glomerulosa Mineralocoicoids (aldosterone) Angiotesin II, K+ Zona fasiculata Glucocoticoids (coisol, coicosterone) ACTH Zona Reticularis Sex steroids (DHEA, DHEA-S) ACTH Adrenal medulla Catecholamines(Epinephrine, norepinephrine) DIffuse sympathetic discharge(stress) REf: Guyton and Hall 13th edition Pgno: 965,966', 'role': 'assistant'}]