This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Which of the following vitamin should not be supplemented in a patient of parkinsonism on levodopa therapy \nSelect and explain. \nA. Thiamine, B. Pyridoxine, C. Cobalamine, D. Pantothenic acid', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Pyridoxine acts as cofactor for Dapa decarboxylase enzyme that converts levodopa to dopamine.\xa0\nAs peripheral conversion can cause postural hypotension, nausea & vomitting and also makes the therapy ineffective. Pyridoxine should not be supplemented.', 'role': 'assistant'}]