This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': "Burkitt's lymphoma is associated with which of the following genetic abnormality- \nSelect and explain. \nA. t(9:22), B. del.5q, C. t(8:14), D. t(17:15)", 'role': 'user'}, {'content': "Answer: C \nExplanation: Ans. is 'C' i.e., t(8:14) o t(8:14) is the most common translocation seen in association with Burkin's Lymphoma. # Demonstration ofvety high proliferative fraction and the presence of the t (8:14) or one of its variants t (2:8) or t(8:22) can be confirmatory of Burkiti s lymphoma/leukemia Translocation in Burkitt's Lymphoma Burkitt s lymphoma/leukemias are associated with reciprocal translocations involving the c-myc gene on chromosome 8 | | Most common translocation (70%cases) Less common translocations t (8 : 14): c- may gene on chromosome 8 and lgH heavy chain on chromosome 14 t (8 : 22) c- myc gene on chromosome 8 and l-light chain on chromossome 22 t (2 :8): c- mye gene on chromosome 8 and l-light chain on chromosome -2", 'role': 'assistant'}]