This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'True statements about Neostigmine are:  a) It is a quarternary ammounium compound b) It is metabolised by liver c) It can cross the blood brain barrier d) Prominent effect on cardiac muscle e) It possess agonistic action on NM receptors \nSelect and explain. \nA. ad, B. bc, C. ae, D. cd', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Neostigmine is a reversible cholinesterase inhibitor. It\xa0is a quarternary\xa0ammonium compound (lipid insoluble\xa0agent), so it does not cross blood-brain-barrier.\nIt is partly hydrolyzed by serum cholinesterase and\xa0partly excreted unchanged by the kidneys.\nIt possesses some agonistic action on NM receptors.', 'role': 'assistant'}]