This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Pseudo-myxoma peritonei occur due to? \nSelect and explain. \nA. Dysgerminoma, B. Brenner s tumor, C. Theca cell tumor, D. Mucinous cystadenosarcoma', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Pseudomyxoma peritonei (PMP) is a clinical condition caused by cancerous cells (mucinous\xa0adenocarcinoma) that produce abundant mucin or gelatinous ascites.\nThe primary tumor appears to arise from the MUC2 expressing goblet cells and most commonly\xa0from these cells in the appendix. The K-Ras and p53 genes may be involved in the oncogenesis. It may\xa0be diagnosed with a range of conditions.\nWhile the majority of these cases are associated with appendiceal carcinoma\xa0other conditions\xa0may also be found, including disseminated peritoneal adenomucinosis (DPAM), peritoneal carcinomas,\xa0several mucinous tumors (mucinous adenocarcinoma, mucinous cystadenoma, and mucinous\xa0cystadenocarcinoma), as well as other disease states\nThis will result in compression of organs and will destroy the function of colon, small intestine, stomach, or other organs. Prognosis with treatment in many cases optimistic, but the disease is lethal if\xa0untreated, with death by cachexia, bowel obstruction, or other types of complications.', 'role': 'assistant'}]