This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Medicine
[{'content': 'All are the causes of nephrocalcinosis in granulomatous disease except - \nSelect and explain. \nA. Increased absorption of ca from intestine, B. Increased conversion to 1,25 (OH )2 D, C. Increased bone resorption, D. Mutation in calcium sensing receptor', 'role': 'user'}, {'content': 'Answer: D \nExplanation: In granulomatous diseases ,granulomas have 1alpha hydroxylase activity . So there is increased conversion of 25(OH) D to 1,25(OH) 2 D. Increased active vitamin d INCREASES-reabsorption of calcium in PCT, bone resorption ,absorption of ca in intestine-resulting in hypercalcemia. Hypercalcemia results in-nephrocalcinosis, nephrolithiasis ,nephrogenic diabetes insipidus . Ref:Harrison 20 th edition pg no 2603', 'role': 'assistant'}]