This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Following is not true about the gene mutations leading to breast carcinoma? \nSelect and explain. \nA. Most common mutation in inherited breast carcinoma is BRCA 1, B. BRCA 1 mutation is present in most of the cases of breast carcinoma, C. Inherited breast carcinomas make about 3 % of the total cases, D. p53 mutation also increases chances of colon and brain cancer', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., BRCA 1 mutation is present in most of the cases of breast carcinomaGenetic mutations associated with breast cancer are of two types -i) Germline mutations (inherited mutations)Involved in familial cases of breast cancer.ii) Somatic mutations (acquired mutation)Involved in sporadic cases of breast cancer", 'role': 'assistant'}]