This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Which of the following is responsible for adhesion of platelets to the vessel wall? \nSelect and explain. \nA. Von Willebrand factor, B. Factor IX, C. Fibrinogen, D. Fibronectin', 'role': 'user'}, {'content': 'Answer: A \nExplanation: the Von-Willebrand factor is responsible for adhesion of platelets to the vessel wall.\n“Endothelial injury allows platelets to contact the underlying extracellular matrix;\nsubsequent adhesion occurs through interactions with von Willebrand factor (VWF),\nwhich is a product of normal endothelial cells and an essential cofactor for platelet binding to matrix elements."—', 'role': 'assistant'}]