This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Which of the following is a Dihydropteroate synthase (DHPS) inhibitor? \nSelect and explain. \nA. Pyrimethamine, B. Trimethoprim, C. Methotrexate, D. Dapsone', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Dapsone, PAS, Sulphonamide > inhibit DHPS enzyme Pyrimethamine, Methotrexate, Trimethoprim - acts by inhibiting DHFR (Dihydrofolate reductase) enzyme.', 'role': 'assistant'}]