This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetics, Subject name: Pathology
[{'content': 'In an Autosomal Dominant disorder, mother is affected but is heterozygous. Father is normal. What are the chance of disease in children? \nSelect and explain. \nA. 50% affected, B. 25% affected, C. 75% affected, D. All affected', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. (a) 50% affected(Ref: Robbins 9th/pg 140; 8th/pg 140)In an Autosomal Dominant disorder, mother is affected but is heterozygous and father is normal.Therefore, the chances of disease in children is 50%', 'role': 'assistant'}]