This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous (Gynae), Subject name: Gynaecology & Obstetrics
[{'content': 'Which of the following can prevent neural tube defects in pregnancy? \nSelect and explain. \nA. Iron, B. Vit B12, C. Folic acid, D. Zinc', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans: c (Folic acid) Ref: Dutta, 6th ed, p. 104, 409Folic acid is supplemented in the first trimester to prevent neural tube defects.Folic acid supplementation:1. Normal pregnancy -0.5 mg in first trimester2. Pregnancy with history of NTD - folic acid 4mg daily, 1 month before conception continued for 12 weeks of pregnancy.Folic acid requirements - ICMR recommendations:1. Healthy adults -100 pg / day2. Pregnancy - 400 pg / day3. Lactation -150 pg /day4. Children -100 pg / dayBRIDGE:unmanifested deficiency of folic acid has been implicated as a cause of abruption placenta.', 'role': 'assistant'}]