This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Substance Related and Addictive Disorders, Subject name: Psychiatry
[{'content': 'A 40 years old patient who has been consuming cannabis regularly for last 20 years comes to you in withdrawal. What is the most frequently seen withdrawal symptom? \nSelect and explain. \nA. Yawning, B. Seizures, C. Irritability, D. Tremors', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Irritability is the most common cannabis withdrawal syndrome Withdrawal symptoms- Irritability Depressed mood Sleep disturbances Headache', 'role': 'assistant'}]