This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Neoplasia, Subject name: Pathology
[{'content': 'Tumor suppressor gene responsible for lung squamous cell carcinoma is? \nSelect and explain. \nA. p53, B. Rb, C. PTEN, D. p63', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., p53 Different genes involved in lung carcinoma* c-MYC and RB - small cell cancer* RAS and p 16 - non-small cell cancer* p53 - both small and non-small cell, but highest in squamous cell carcinoma* K-RAS -adenocarcinoma# In small cell cancer there is high expression of the antiapoptotic gene BCL 2 and low expression of the Proapoptotic gene BAX.", 'role': 'assistant'}]