This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Vitamins and Minerals, Subject name: Biochemistry
[{'content': 'Excess dietary intake of carbohydrates increases the RDA level of: \nSelect and explain. \nA. Thiamine, B. Vit E, C. Vit C, D. Pantothenate', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Thiamine is needed for only 4 enzymes in the body.They are:- Pyruvate dehydrogenase a keto glutarate dehydrogenase Transketolase Branched chain ketoacid dehydrogenase. Branched chain ketoacid dehydrogenase is involved in the metabolism of amino acids Rest all the 3 enzymes are involved in carbohydrate metabolism. So, increased carbohydrate intake increases the requirement of thiamine also. Transketolase enzyme estimation is used in thiamine deficiency', 'role': 'assistant'}]