This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Glaucoma, Subject name: Ophthalmology
[{'content': 'Which of the following is the mechanism of action of IOP reduction of carbonic anhydrase inhibitors? \nSelect and explain. \nA. Increase uveoscleral outflow, B. Increase trabecular meshwork outflow, C. Decrease aqueous production, D. All of the above', 'role': 'user'}, {'content': 'Answer: C \nExplanation: CA inhibitor: MOA- Inhibition of carbonic anhydrase isozymes present in ciliary processes of the eye with the consequent reduction of bicarbonate and aqueous humor secretion. Acetazolamide- (oral), Dorzolamide & Brinzolamide(topical). Mechanism of action: Decrease Aqueous Humor production. Oral CA inhibitors are Rapidly acting drug, can be used to terminate acute attack. S/E: Kidney stone, hypokalemia, acidosis, adrenal gland, renal failure . is an emergency drug & should not be answered as DOC for any type of glaucoma.', 'role': 'assistant'}]