This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Mutation seen in malignant melanoma \nSelect and explain. \nA. P53, B. CDKN2A, C. RET, D. Rb', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Germline mutations in CDKN2A gene are found in about 40% of familial malignant melanoma cases.', 'role': 'assistant'}]