This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Central Nervous system, Subject name: Pharmacology
[{'content': 'Which of the following antiepileptic agent does not act Na+ channel modulation? \nSelect and explain. \nA. Vigabatrin, B. Phenytoin, C. Valproate, D. Lamotrigne', 'role': 'user'}, {'content': 'Answer: A \nExplanation: it is an inhibitor of GABAtransaminase, the enzyme which degrades GABA. Anticonvulsant action may be due to increase in synaptic GABA concentration REF KD TRIPATHI 8TH ED.', 'role': 'assistant'}]