This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': 'True statement regarding a 3-week old child with Phenylketonuria is all, except – \nSelect and explain. \nA. Provocative protein meal tests helps in the diagnosis, B. Tyrosine becomes an Essential amino–acid in diet, C. Serum Phenylalanine is increased and urinary Phenyl Pyruvate level is elevated, D. Phenylalanine should be completely stopped in diet', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Phenylamine should be restricted in diet, however, it should not be completely eliminated, as it is necessary for normal growth.\nPhenylketonuria \n\nIt is an autosomal recessive condition.\nThere is a deficiency of enzyme phenylalanine hydroxylase.\n\nPathophysiology\n\nBecause phenylalanine is not metabolised by hydroxylase, metabolism is shifted to the alternative pathway (see above explanation) and there is an increased concentration of -\n\n\nPhenylalanine \xa0 \xa0 \xa0\nPhenylpuruvic acid\xa0\nPhenylacetic acid\xa0\nPhenylacetic acid\xa0\n\n\nBecause phenylalanine is not converted into tyrosine, tyrosine becomes an essential amino acid.\n\nTreatment :\n\nThe goal of therapy is to reduce phenylalanine and its metabolites in body fluids in order to minimize or prevent brain damage.\nAdministration of low phenylalanine levels is the mainstay of treatment.\nDietary treatment should be started as soon as after birth as the diagnosis is established.\nBecause phenylalanine is not synthesized in the body, Tyrosine becomes an essential A.A. in this disorder, and its adequate intake must be ensured.', 'role': 'assistant'}]