This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: D.O.C, Subject name: Pharmacology
[{'content': 'Drug of choice for peptic ulcer disease caused by chronic use of NSAIDS: \nSelect and explain. \nA. Pirenzepine, B. Loratadine, C. Misoprostol, D. Esomeprazole', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans. D. EsomeprazoleMisoprostol and esomeprazole are both used for NSAID induced ulcer. But PPI are more efficacious for this condition.', 'role': 'assistant'}]