This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hematology, Subject name: Pathology
[{'content': 'VWF factor deficiency causes: \nSelect and explain. \nA. | Platelet adhesion, B. | Factor VIII in plasma, C. Defective platelet adhesion, D. All of the above', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Deficiency of Von willebrand factor (VWF -promote platelet adherence and activation) causes | Platelet adhesion ( |BT ) | Intrinsic pathway activity ( | aPTT) | Factor VIII in plasma C/F Mucosal bleeding - Petechiae /purpura /epistaxis / melena Tissue bleeding Rx - Desmopressin for mild form - Cryoprecipitate for severe form', 'role': 'assistant'}]