This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anatomy of skin, Subject name: Dental
[{'content': 'Langerhans cells in skin fall under which category \nSelect and explain. \nA. Sensory neurons, B. Pigment producing cells, C. Antigen presenting cell, D. Keratin synthesising cell', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Langerhans Cell (LC) * Bone marrow-derived dendritic cell with monocyte-macrophage lineage found in stratum spinosum; constitutes 3-5% of cells of epidermis; contains actin and vimentin * Critical in recognizing and presenting foreign antigens to specific T lymphocytes . * Connected to keratinocytes E-cadherin receptors . * On EM, Langerhans cell with folded nucleus and distinct intracytoplasmic organelles (Birbeck granules: striated appearance with either rod-shape and/or tennis-racquet-shape). * Exposure to UV radiation causes depletion of LCs and decreases ability to present antigen. Ref:- Dermatology by sima Jain; pg num:- 9', 'role': 'assistant'}]