This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': 'In thromboasthenia there is a defect in – \nSelect and explain. \nA. Platelet aggregation, B. Platelet adhesion, C. Decreased ADP release, D. Desordered platelet secretion', 'role': 'user'}, {'content': "Answer: A \nExplanation: Platelet adhesion\n\nPlatelet adhesion referes to the binding of platelets to subendothelial matrix.\nPlatelet membrane glycoprotein Ib-IX is essential for platelet adhesion to subendothelial matrix.\n\n\nPlatelet aggregation\n\nPlatelet aggregation referres to adherence of platelets to one another.\nPlatelet membrane glycoprotein ddb-IIIa helps in aggregation.\n\nCongenital dysfunction of platelet\n1. Bernard-soulier syndrome\n\nDefect in platelet adhesion due to inherited deficiency of glycoprotein Ib-IX.\n\n2. Glanzmann's thrombasthenia\n\nDefect in platelet aggregation due to inherited deficiency of glycoprotein Ilb-IIIa.", 'role': 'assistant'}]