This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Impoant Genetic Syndromes, Subject name: Pediatrics
[{'content': 'An albino girl gets married to a normal boy. What are the chances of their having an affected child and what are the chances of their children being carriers? \nSelect and explain. \nA. None affected, all carriers, B. All normal, C. 50% carriers, D. 50% affected, 50% carriers', 'role': 'user'}, {'content': 'Answer: A \nExplanation: **Albinism is autosomal recessive; Female here is affected (2 defective genes), while male is normal (both genes normal). **So each offspring (son/daughter) will inherit one defective gene only, from the mother. **So all children will be carriers of albinism and none will be affected.', 'role': 'assistant'}]