This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'What is/are true about bilirubin?a) Conjugation is rate limiting stepb) Bilirubin has affinity for elastinc) Conjugated bilirubin is maximum in bloodd) Total Hb content of body is 750 gm \nSelect and explain. \nA. c, B. d, C. ab, D. bd', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Excretion of conjugated bilirubin into biliary canaliculi is the rate limiting step in bilirubin metabolism\nBilirubin has affinity for elastin, therefore jaundice is most easily seen in the sclera.\nNormally unconjugated bilirubin is more than conjugated bilirubin, in blood\n\tTotal bilirubin\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0→ 0.3 –\xa01.9 mg/dl\n\tConjugated bilirubin\xa0\xa0\xa0\xa0\xa0→ 0 to 0.3 mg/dl\n\tUnconjugated bilirubin\xa0\xa0→ Total – conjugated (0.3 –\xa01.6 mg/dl)\nNormally hemoglobin content of blood is between 120-160 gm/L (Harrison 17th/e p. A-2), and a normal adult usually have 5 litre of blood. So total hemoglobin is 600 - 800 gm.', 'role': 'assistant'}]