This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Cyclo-oxygenase-1 (COX-1) isoenzyme: \nSelect and explain. \nA. Is increased by inflammation, B. Is predominant mode of action of Indomethacin, C. Is increased by lipopolysaccharide ie G –ve endotoxin, D. Is NOT involved in gastric mucosal protection', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Option A, C & E is incorrect as Cyclo-Oxygenase -1 (COX-1) is a constitutive Enzyme.\nOption B is correct as – Indomethacin does affect it as it’s nonselective.\n\u200bOption D is incorrect as COX-1, plays a central role in protection of the gastric mucosa, by helping in the synthesis of Prostaglandins.', 'role': 'assistant'}]