This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'All of the following are decreased in nephrotic syndrome, except- \nSelect and explain. \nA. Serum transferrin, B. Serum fibrinogen, C. Serum ceruloplasmin, D. Serum albumin', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., Serum Fibrinogen Fibrinogen level is increased in nephrotic syndrome d/t increased hepatic synthesis of fibrinogen. o The largest propoion of protein lost in urine is albumin. o Sometimes, globulins can also be excreted -4 Immunoglobulin excretion increases the susceptibility of infection. o Other proteins which are decreased - Transferrin ---> Microcytic hypochromic anemia. Cholecalciferol binding protein --> hypocalcemia Thyroxine binding globulin --> decreased thyroxine level. Antithrombin III --> hypercoagulability Ceruloplasmin", 'role': 'assistant'}]