This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'In Wilms tumor, the following leads to the emergence of resistance to chemotherapy - \nSelect and explain. \nA. Nephrogenic rests, B. Monophasic morphology, C. Anaplasia, D. Capsular infiltration', 'role': 'user'}, {'content': 'Answer: C \nExplanation: None', 'role': 'assistant'}]