This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'The most common late CNS complication of HIV is \nSelect and explain. \nA. Dementia, B. Ataxia, C. Seizures, D. Deliruim', 'role': 'user'}, {'content': 'Answer: A \nExplanation: CNS involvement in AIDS \n\nInvolvement of the CNS is a common and important manifestation of AIDS.\nIn addition to the lymphoid system, the nervous system is a major target of HIV infection.\nMacrophages and microglial cells in the central nervous system that belong to the monocyte and macrophage lineage are predominant to the types in the brain that are infected with HIV.\nIt is widely believed that HIV is carried into the brain by infected monocytes.\nNinety per cent of patients demonstrate some form of neurological involvement at autopsy.\nIn addition to opportunistic infection and neoplasm, several virally determined neuropathological changes occur.\n\nThese include\n\nA self limited meningioencephalitis.\nAseptic meningitis\nVascular myelopathy\nPeripheral neuropathies and\nMost commonly a progressive encephalopathy designated clinically as the AIDS dementia complex. AIDS dementia complex\nIt is the commonest neurological complication in subacute or chronic HIV encephalitis.\nEarlier it was called AIDS encephalopathy or encephalitis.\nIt present as slowly or rapidly progressive dementia accompanied by abnormalities of motor function.', 'role': 'assistant'}]