This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'An adult old man gets burn injury to his hands. Over a few weeks, the burned skin heals without the need for skin grafting. The most critical factor responsible for the rapid healing in this case is - \nSelect and explain. \nA. Remnant skin appendages, B. Underlying connective tissues, C. Minimal edema and erythema, D. Granulation tissue', 'role': 'user'}, {'content': 'Answer: A \nExplanation: The skin consists of two layers\n\n1. Epidermis\n\nMost superficial layer\xa0of the skin. It is constantly replaced from the basal layer.\n\n2. Dermis\n\nIt is thicker than epidermis and supplies the strength and integrity to the skin\nIt has a rich blood supply\nIt contains adnexal structures i.e.→ Hair follicles, Sebaceous glands, Sweat glands.\nThe importance of these adnexal structures is that they contain epithelial cells that can proliferate and can heal a partial thickness wound by epithelialisation.\n\nSuperficial burns\n\nInvolve only epidermis and superficial dermis\nThe adnexal structures are left intact so they can heal by epithelialisation.\nDeep burns\n\nIn deep burns, all the adnexal structures are lost so they can only heal by secondary intention with scarring.\n\nPresence of granulations simply indicate healing, one cannot tell whether it is healing by primary intention or by secondary intention.', 'role': 'assistant'}]