This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: JIPMER 2019, Subject name: Pharmacology
[{'content': 'A patient on Bilonatumomab for refractory B cell All is now resistance to the drug. Which drug to be used:- \nSelect and explain. \nA. Vorinostat, B. Brentuximab, C. Pembrolizumab, D. Tisagenlecleucel', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Drug Mechanism Use Vorinostat HDAC inhibitor Cutaneous T cell lymphoma Brentuximab Man against CD30 Hodgkin lymphoma Pembrolizumab PD-1 Melanoma Lung Cancer Head and neck cancer Tisagenlecleucel Ca therapy ALL Blinatumomab Bispecific t-cell engages ( targets CD19 and CD3) ALL', 'role': 'assistant'}]