This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Basics of DNA, Subject name: Biochemistry
[{'content': 'DNase hypersensitive regions are \nSelect and explain. \nA. Methylated DNA, B. Heterochromatin region, C. Transcriptionally active chromatin, D. RNA bound DNA region', 'role': 'user'}, {'content': "Answer: C \nExplanation: DNase I (deoxyribonuclease I) Can digest the DNA. Can't act when the DNA is bound to proteins, i.e, heterochromatin state. Can act only when the chromatin is decondensed, So, sensitivity to DNase enzyme is indirectly propoional to the degree of compaction of chromatin. Regions of DNA which are actively transcribed are hypersensitive to DNase I digestion.", 'role': 'assistant'}]