This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'All of the following are criteria for high risk of deveoping chloroquine retinopathy except \nSelect and explain. \nA. Duration of use > 5 years, B. Seen at a dose of >250mg/d or >3mg/kg, C. >480g total dose, D. Presence of renal failure', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Criteria of High Risk for Developing Chloroquine Retinopathy\n\nDosage > 6.5 mg/kg hydroxychloroquine or > 3 mg/kg chloroquine\nDuration of Use > 5 years\nHigh fat level (unless dosage is appropriately low)\nPresence of renal/liver disease\nPresence of concomitant retinal disease\nAge > 60 years\n\nPreviously cumulative dose of > 1g/Kg was considered as a high risk factor which is now not considered.', 'role': 'assistant'}]