This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunology, Subject name: Microbiology
[{'content': 'Type I hypersensitivity, the mediator is: \nSelect and explain. \nA. IgE, B. IgE, C. IgM, D. IgC', 'role': 'user'}, {'content': 'Answer: A \nExplanation: [A) (IgE) (161-AN 7th) (202-206-CP)Type of reactionClinical syndromeMediatorsType I - IgE1. Anaphylaxis2. Atopy P.K. reactionIgE, histamine and other pharmacological agents', 'role': 'assistant'}]