This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Fibroblast is derived from- \nSelect and explain. \nA. Macrophage, B. Endothelium, C. Vessels, D. Local mesenchyme', 'role': 'user'}, {'content': 'Answer: D \nExplanation: o Fibroblasts produce the glycosaminoglycans, collagens, elastic fibers, reticular fibres and glycoproteins\xa0that can be seen in the extracellular matrix. They also produce cytokineTSLP.\no Fibroblasts are originally derived from primitive mesenchyme and therefore display the filament protein\xa0vimentin, which acts as a marker of mesodermal origin.\no Inactive fibroblasts are called fibrocytes. When tissue damage has occurred, the fibrocytes are stimulated\xa0to undergo mitosis or multiplication by replication and division.\no Transforming growth factor P induces proliferation offibroblasts. It is chemotactic for fibroblasts', 'role': 'assistant'}]