This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chronic Inflammation, Subject name: Pathology
[{'content': 'Non-caseating granuloma is characteristically seen in: \nSelect and explain. \nA. Syphilis, B. Sarcoidosis, C. Tuberculosis, D. Cat-scratch disease', 'role': 'user'}, {'content': 'Answer: B \nExplanation: In granulomas associated with ceain infectious organisms (most classically Mycobacterium tuberculosis), a combination of hypoxia and free radical-mediated injury leads to a central zone of necrosis. Grossly, this has a granular, cheesy appearance and is therefore called caseous necrosis. Microscopically, this necrotic material appears as amorphous, structureless, eosinophilic, granular debris, with complete loss of cellular details. The granulomas in Crohn disease, sarcoidosis, and foreign body reactions tend to not have necrotic centers and are said to be non-caseating.', 'role': 'assistant'}]