This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Virology, Subject name: Microbiology
[{'content': 'First antibody to appear in hepatitis - \nSelect and explain. \nA. IgM anti-Hbe, B. IgG-anti-Hbe, C. IgM-anti-HBc, D. IgM anti-HBs', 'role': 'user'}, {'content': "Answer: C \nExplanation: Anti-HBV appears in serum a week or two after the appearance of HBsAg. It is therfore the earliest antibody marker to be seen in blood? long before anti-HBe or anti-HBs. REF:ANANTHANARAYAN AND PANIKER'S TEXTBOOK OF MICROBIOLOGY 9TH EDITION PAGE NO-546", 'role': 'assistant'}]