This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'All the following are the effects of oestrogen, EXCEPT: \nSelect and explain. \nA. Beneficial effect on cognition, B. Reduced osteoclastic activity, C. Increased osteoblastic activity, D. Increased protein C and S levels', 'role': 'user'}, {'content': 'Answer: D \nExplanation: The effects of oestrogen on the skeletal system includes: 1) Increased osteoblastic activity 2) Reduced osteoclastic activity 3) Prevents osteoporosis 4) Promotes fusion of epiphyses Also know Oestrogen increases factor II, III, IX, X, XII and decreases protein C , S and antithrombin III. Ref: Essentials of Gynaecology by Lakshmi Seshadri, Edition 1, page - 44', 'role': 'assistant'}]