This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
[{'content': 'RET proto oncogene mutation is a hallmark of which of the following tumors? \nSelect and explain. \nA. Medullary carcinoma thyroid, B. Astrocytoma, C. Paraganglioma, D. Huhle cell tumor thyroid', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e. Medullary carcinoma thyroid Mutations in RET proto-oncogene are responsible for MEN2A, MEN2B, and Familial Medullary thyroid carcinoma. RET protooncogene codes for trans-membrane protein tyrosine kinase Familial cases of MTC are now detected by genetic screening for RET mutations, which identifies individuals who will develop medullary cancer later in life.", 'role': 'assistant'}]