This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Muscle, Subject name: Physiology
[{'content': "True about Duchenne's muscular dystrophy is: \nSelect and explain. \nA. It is an X- linked recessive disorder, B. Skeletal muscle wasting occurs due to abnormalities of the contractile filaments, C. Muscle wasting occurs in the pelvic region only, D. It is a form of titanopathy", 'role': 'user'}, {'content': "Answer: A \nExplanation: Duchenne's muscular dystrophy (DMD) is an X-linked recessive disorder. (option A is correct.) There is a genetic defect in the dystrophin gene; it results in deficiency of the protein dystrophin in skeletal muscle Dystrophin is a large protein that is present on the intracellular surface of the sarcolemma, it makes dystrophin-glycoprotein complex.. In DMD, there is severe muscle wasting; death may occur from respiratory failure.", 'role': 'assistant'}]