This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Medicine
[{'content': 'Side effects of phenytoin are all EXCEPT \nSelect and explain. \nA. Gum hypertrophy, B. Hirsutism, C. Microcytic anemia, D. Osteomalacia', 'role': 'user'}, {'content': 'Answer: C \nExplanation: (C) Microcytic anemia # At therapeutic levels:> Gum hypertrophy: Commonest (20% incidence), more in younger patients, can be minimized by maintaining oral hygiene.> Hirsutism, coarsening of facial features (troublesome in young girls), aerie.> Hypersensitivity reactions are--rashes, DLE, lymphadenopathy; neutropenia is rare but requires discontinuation of therapy.> Megaloblastic anaemia: Phenytoin decreases folate absorption and increases its excretion.> Osteomalacia: Phenytoin desensitizes target tissues to vitamin D and interferes with calcium metabolism.> It can inhibit insulin release and cause hyperglycaemia.> Used during pregnancy--can produce foetal hydantoin syndrome (hypoplastic phalanges, cleft palate, hare lip, microcephaly), which is probably caused by its areneoxide metabolite.', 'role': 'assistant'}]