This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology and breast, Subject name: Surgery
[{'content': 'For Ca breast best chemotherapeutic regimen \nSelect and explain. \nA. Cyclophosphamide, methotrexate, 5-fluorouracil, B. Methotrexate, cisplatin, C. Cisplatin, adriamycin, steroid, D. Methotrexate, adriamycin, steroid', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Chemotherapy using first generation regime such as 6-monthly cycle of cyclophosphamide, methotrexate and 5- fluorouracil(CMF) will achieve a 25% reduction in the risk of relapse over a 10-15 year peroid. Reference: Bailey and Love, 27th Edition, page no : 878.', 'role': 'assistant'}]