This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy: General Principles, Subject name: Pharmacology
[{'content': 'A 26 year old patient presents with suspected pneumococcal meningitis. CSF culture is sent for antibiotic sensitivity. Which empirical antibiotic should be given till culture sensitivity result come? \nSelect and explain. \nA. Penicillin G, B. Ceftriaxone + metronidazole, C. Doxycycline, D. Cefotaxime + vancomycin', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans. (D) Cefotaxime + vancomycin(Ref: Harrison 18/e p3414)Antibiotics Used in Empirical Therapy of Bacterial Meningitis and Focal CNS InfectionsIndicationAntibioticInfants <3 monthsAmpicillin + Cefotaxime3 months to 55 yearsCefotaxime (Ceftriaxone) + VancomycinAdults >55 yearsAmpicillin + Cefotaxime (Ceftriaxone) + VancomycinHospital-acquired meningitis post-traumatic or post-neurosurgery meningitis, neutropenic patients, or patients with impaired cell-mediated immunityVancomycin + Cefepime', 'role': 'assistant'}]