This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Fluid and electrolytes, Subject name: Medicine
[{'content': 'Which ion channel is effected in hypokalemic periodic paralysis? \nSelect and explain. \nA. K+, B. Na+, C. CI-, D. Ca2+', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Hypokalemic periodic paralysis is due to calcium channel mutations. Hypokalemic periodic paralysis, in which serum potassium drops during a paralytic episode, is the most common of the inherited periodic paralyses. Ref Davidson 23rd edition pg 366', 'role': 'assistant'}]