This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Pharmacokinetics, Subject name: Pharmacology
[{'content': 'Which is the best way to manage a patient present with aspirin poisoning \nSelect and explain. \nA. Make urine acidic with NH4G1, B. Make urine alkaline with NaHCO3, C. Treat with N-acetyl cysteine, D. Do gastric lavage', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. (b) Make urine alkaline with NaHCO3Refi.KDT 6th ed. /16* Aspirin is an acidic drug, it readily crosses any acidic medium. To treat this toxicity, make the urine alkaline with NaHCO3.* Now, this acid drug can't be reabsorbed from the basic medium, and it readily gets excreted from the body.Also Know* In basic drug poisoning like amphetamine, we acidify the urine with NH4C1~ to change the medium, which opposes reabsorption and hence excretion.* N-acetyl cysteine is the DOC for paracetamol poisoning", 'role': 'assistant'}]