This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pharmacology, Subject name: Pharmacology
[{'content': 'Paial agonist can antagonise the effects of a full agonist because it has \nSelect and explain. \nA. High affinity but low intrinsic activity, B. No affinity and low intrinsic activity, C. Low affinity but high intrinsic activity, D. High affinity but no intrinsic activity', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Agonists:- Have both affinity and maximal intrin-sic activity. Competitive antagonists :- Have affinity but no intrinsic activity. Paial agonists:- Have affinity and submaximal intrinsic activity. Inverse agonists:- Have affinity but intrinsic activity with a minus sign (IA between 0 and -1). Ref:- kd tripathi; pg num:-41,42', 'role': 'assistant'}]