This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Mood Disorders, Subject name: Psychiatry
[{'content': 'The clinical effects of the antidepressant drugs is mainly based on: \nSelect and explain. \nA. Change in neurotransmitter receptor sensitivity, B. Decreased levels of neurotransmitters, C. Change in efficacy of neurotransmitters, D. None of the above', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Secondary to increased neurotransmitter levels by anti depressants, the receptor sensitivity changes over a course of time and that is responsible for antidepressant effect.', 'role': 'assistant'}]