This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Amplification of N-Myc is associated with which a tumor? \nSelect and explain. \nA. Neuroblastoma, B. Retinoblastoma, C. Osteosarcoma, D. Neuroma', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Amplification of N-Myc is associated with a variety of tumors, most notably neuroblastomas.\nThis gene is a member of the MYC family of transcription factors and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA.', 'role': 'assistant'}]