This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Tram track appearance is seen in which of the following conditions: March 2013 \nSelect and explain. \nA. IgA nephropathy, B. RPGN, C. Membranoproliferative glomerulonephritis, D. Membranous glomerulonephritis', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans. C i.e. Membranoproliferative glomerulonephritis Membranoproliferative glomerulonephritis ("MPGN")/ Mesangiocapillary glomerulonephritis, It is a type of glomerulonephritis caused by deposits in the kidney glomerular mesangium and basement membrane (GBM) thickening, activating complement and damaging the glomeruli. MPGN accounts for approximately 4% of primary renal causes of nephritic syndrome in children and 7% in adults. It should not be confused with membranous glomerulonephritis, a condition in where the basement membrane is thickened, but the mesangium is not. The GBM is rebuilt on top of the deposits, causing a "tram tracking" appearance under the microscope. Mesangial cellularity is increased.', 'role': 'assistant'}]