This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Musculoskeletal system, Subject name: Pathology
[{'content': 'a-synuclein, a lipid-binding protein, is a major component of \nSelect and explain. \nA. Lewy bodies, B. Amyloid, C. Tau protein, D. Neurofibrillary tangles', 'role': 'user'}, {'content': 'Answer: A \nExplanation: a-synuclein, an abundant lipid-binding protein normally associated with synapses. This protein was then demonstrated to be a major component of the Lewy body, which is the diagnostic hallmark of Parkinson diseaseRobbins pathology9e pg: 1294', 'role': 'assistant'}]