This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Vestibulobullous disorders, Subject name: Dental
[{'content': "Skin Disease not showing DIF \nSelect and explain. \nA. Darrier's disease, B. Hailey-Hailey disease, C. Cicatricial Pemphigoid, D. Dermatitis herpatiformis", 'role': 'user'}, {'content': "Answer: A \nExplanation: In Direct immunofluorescence, intercellular IgG -fishnet pattern throughout the epidermis is seen in pemphigus vulgaris. Benign familial pemphigus (Hailey-Hailey disease). Granular IgA at basement membrane zone and tips of papillae is seen in Dermatitis herpetiformis. Darier's disease (keratosis follicularis /darier white disease )is an autosomal dominant inherited disorder usually diagnosed by its clinical appearance of brown scaly papules in seborrhoeic areas, palmar pits, nail changes,acrokeratosis and oral lesions. A positive family history will be there. skin biopsy can also be done. Page no.323,329,287 Reference IADVL's concise textbook of dermatology", 'role': 'assistant'}]