This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Opioids and Alcohols, Subject name: Pharmacology
[{'content': 'The combination of alcohol and disulfiram results in nausea and hypotension as a result of accumulation of: \nSelect and explain. \nA. Acetaldehyde, B. Acetate, C. Methanol, D. NADH', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Disulfiram is an aldehyde dehydrogenase inhibitor that can be used for de-addiction of chronic alcoholics. Due to inhibition of aldehyde dehydrogenase, there is accumulation of acetaldehyde that leads to several distressing symptoms (which strengthens the resolution of a person to quit alcohol).', 'role': 'assistant'}]