This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': 'Common ocular manifestation in Trisomy 13 is – \nSelect and explain. \nA. Capillary hemangioma, B. Bilateral microphthalmos, C. Neurofibroma, D. Dermoid cyst', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Cleft lip, cleft palate, scalp defects suggest Trisomy 13 or patau syndrome.\nTrisomy 13 and Trisomy 18 share several clinical features.\nThe highest discriminatory values are for ectodermal scalp defects and harelip and cleft palate in trisomy 13 and\xa0elongated skull and simple arches on all digits for trisomy 18.\xa0\n\nTrisomy 13 (Patau syndrome)\n\nCleft lip often midline\nFlexed-fingers with polydactyly\nOcular hypotelorism\nBulbous nose\nLow set malformed ears\nSmall abnormal skull\nCerebral malformation especially holoprosencephaly\nMicroophthalmia\nCardiac malformations\nScalp defects\nHypoplastic or absent ribs\nVisceral and genital anomalies\n\nTrisomy 18 (Edward syndrome)\xa0\n\nLow birth weight\nClosed fists with index finger overlapping the 3rd\xa0digit and the 5th\xa0digit overlapping the 4th.\nNarrow hips with limited abduction\nShort sternum\nRocker bottom feet\nMicrocephaly\nProminent occiput\nMicrognathia\nCardiac and renal malformations\nMental retardation\n15% cases are lethal in 1st\xa0year', 'role': 'assistant'}]