This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pharmacology, Subject name: Pharmacology
[{'content': 'Which of the following is not conveed into an active metabolite? \nSelect and explain. \nA. Lisinopril, B. Fluoxetine, C. Cyclophosphamide, D. Diazepam', 'role': 'user'}, {'content': 'Answer: A \nExplanation: prodrugs are conveed into active metabolites all ACE inhibitors except captopril and lisinopril are prodrugs lisinopril: It is the lysine derivative of enalaprilat: does not require hydrolysis to become an active ACE inhibitor. Fluoxetine has an active demethylated metabolite Diazepam has an active metabolite Desmethyl-diazepam, oxazepam Cyclophosphamide have active metabolite Aldophosphamide, .phosphorarmide mustard, acrolein Ref ;KD Tripathi pharmacology 7th edition (page no; 503,461,22,23)', 'role': 'assistant'}]