This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Neoplasia, Subject name: Pathology
[{'content': 'RET proto-oncogene is associated with which carcinoma? \nSelect and explain. \nA. Hepatocellular Carcinoma, B. MEN, C. Testicular carcinoma, D. Breast carcinoma', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., MEN * RET is a growth factor receptor (receptor tyrosine kinase). RET protein is a receptor for glial cell lined derived neurotrophic factor. RET is normally expressed in parafollicular 'C' cells of thyroid, adrenal medulla and parathyroid cell precursons.* Point mutation in RET protooncogenes is associated with MEN-2A, MEN-2B, medullary thyroid carcinoma and Hirschsprung disease.", 'role': 'assistant'}]