This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General Pharmacology, Subject name: Pharmacology
[{'content': 'True statement regarding first order kinetics is: \nSelect and explain. \nA. Rate of elimination is independent of plasma concentration, B. A constant proportion of plasma concentration is eliminated per unit time, C. Half life increases with dose, D. Clearance decreases with dose', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans. (B) A constant proportion of plasma concentration is eliminated per unit time(Ref: RID 8th/e p38-39)In first order kinetics, rate of elimination is proportional to plasma concentration of the drug. Half life and clearance are constant in first order kinetics.', 'role': 'assistant'}]