This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General anatomy, Subject name: Anatomy
[{'content': 'The following is not a feature of malignant transformation by culturedc \nSelect and explain. \nA. Increased cell density, B. Increased requirement for growth factors, C. Alterations of cytoskeleton structure, D. Loss of anchorage', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ref biology of the cell p357-364 Both normal cells and cancer cells can be cultured in-vitro , however they behave quite differently normal cell: show replicative senescence .is cells pass through limited number of cell division before they decline in vigor and die it may caused by inability to synthesise telomerase', 'role': 'assistant'}]