This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: miscellaneous, Subject name: Biochemistry
[{'content': 'Rate limiting step in gluconeogenesis \nSelect and explain. \nA. Fructose 1, 6 biphosphatase, B. Glucokinase, C. Fructokinase, D. Hexokinase', 'role': 'user'}, {'content': 'Answer: A \nExplanation: 1. Pyruvate carboxylase2. Phosphoenolpyruvate carboxykinase3. Fructose-1-6-bisphosphatase4. Glucose-6-phosphataseGluconeogenesis involves several enzymes of glycolysis, but it is not a reversal of glycolysis. The irreversible steps in glycolysis are circumvented by four enzymes which are designated as the key enzymes of gluconeogenesis.Ref: D M Vasudevan 7th edition Page no: 117', 'role': 'assistant'}]