This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'The most likely diagnosis is a case of the intractable convulsions mental defect and facial nevus is- \nSelect and explain. \nA. Sturge Weber syndrome, B. Tuberous sclerosis, C. Von-Hippen -Lindau disease, D. Von- Reckling-Hausens disease', 'role': 'user'}, {'content': "Answer: A \nExplanation: Sturge Weber syndrome and Von-Reckling-Hausen disease (NF-1) have been explained earlier about other options.\xa0\n\nTuberous sclerosis ( Bourneville's disease)\n\nTuberous sclerosis is characterized by : -\n\n\nCutaneous lesions\xa0→\xa0Adenoma sebaceum, ash-leaf shaped hypopigmented macules, shagreen patches, depigmented nevi.\nSeizures\nMental retardation\n\n\nOther features\xa0\xa0→\xa0Calcified subependymal nodules, Subependymal giant cell astrocytoma, ependymoma,\n\nRhabdomyomas of the heart, and angiomyomas of the kidney, liver, adrenals and pancreas.\nVon Hippel - Lindau syndrome\n\nThis syndrome consists of Retinal, cerebellar and spinal hemangioblastoma.\nRenal cell carcinoma, Pheochromocytoma, benign cyst of the kidney, liver, pancreas and epididymis may also occur.\nPolycythemia may occur due to secretion of erythropoietin from hemangioblastoma.", 'role': 'assistant'}]