This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Autacoids, Subject name: Pharmacology
[{'content': 'Which of the following drugs have covalent interaction with its target \nSelect and explain. \nA. Aspirin, B. Penicillin, C. Nitric oxide, D. Basanta', 'role': 'user'}, {'content': 'Answer: A \nExplanation: covalent interaction means Irreversible inhibition of enzyme. Aspirin irreversibly acitylates the cox enzyme Refer kDT 6/e p185', 'role': 'assistant'}]