This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Medicine
[{'content': 'Short acting anticholinesterase is \nSelect and explain. \nA. Tacrine, B. Edrophonium, C. Pyridostigmine, D. Donepezil', 'role': 'user'}, {'content': 'Answer: B \nExplanation: (B) Edrophonium# Pyridostigmine:> Resembles neostigmine in all respects but is dose to dose less potent and longer acting, less frequent dosing is required in myasthenia gravis.# Edrophonium:> Resembles neostigmine in action, has a brief duration (10-30 min), suitable as a diagnostic agent for myasthenia gravis and for postoperative decurarization.# Tacrine:> It is a lipophilic acridine compound which interacts with ChE in a manner analogous to edrophonium.> It crosses blood-brain barrier and has a longer duration of action.# Donepezil:> Another centrally acting anti AChE that has produced cognitive and behavioral improvement in AD.> It is long acting and suitable for once daily administration.', 'role': 'assistant'}]