This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'NADPH oxidase deficiency causes impaired immunity which of the follwoing process? \nSelect and explain. \nA. Chedickhigasi syndrome, B. Chronic granulomatous disease, C. Leucocyte adhesion defect type 1, D. Leucocyte adhesion defect type 2', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Chronic granulomatous disease is a rare, X-linked deficiency of NADPH oxidase activity which drastically impairs the ability of macrophages and neutrophils to destroy pathogens. Patients are especially vulnerable to mycobacteria, E coli, and staphylococcus since these organisms produces catalase to defend themselves against hydrogen peroxide attack by phagocytes.', 'role': 'assistant'}]