This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.N.S, Subject name: Pharmacology
[{'content': "Which drug doesn't include DMARD: \nSelect and explain. \nA. Chloroquine, B. Vincristine, C. Azathioprine, D. Leflunomide", 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., Vincristine Drugs used for Rheumatoid arthritisDisease modifying antirheumatic drugs (DMARDs)Biologic response modifier (BRMs)Adjuvant drugs1. Immunosuppresants - Methotrexate, azathioprine, cyclosporineo TNF a - inhibitors Etanercept, Infliximab,o Corticosteroids2. SulfasalazineAdalimumab 3. Choloroquine or hydroxychloroquineo IL-1 antagonist 4. LeflunomideAnakinra 5. Gold sod. thiomalate, Auranofin 6. d - Penicillamine Important DM ARDsMechanism of actiono MethotrexateDihydrofolate reductase inhibitoro SulfasalazineSulfapyridine moiety suppresses the generation of superoxide radicals and cytokine production o LeflunomideIs rapidly converted in the body to an active metabolite which inhibits dihydroorotate dehydrogenase .o Hydroxychloroquineo Reduce monocyte 1L-1. consequently inhibiting B-celIso Interferes with antigen processingo Stabilizes lysosome and free radical scavenging.", 'role': 'assistant'}]