This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'Pathologic features of brain in AIDS are all, except \nSelect and explain. \nA. Perivascular giant cell invasion, B. Microglial nodules, C. Vasculitis, D. Temporal lobe infarction', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Unlike most other viral encephalitides, HIV does not seem to infect neurons and perivasculitis is conspicuously absent" - Anderson pathology 10th/e p. 2728\n"Characteristic multinuclear Giant cells of macrophage origin are seen in deep white matter of frontal and temporal lobes particularly in perivascular location" - Anderson p. 10th /e .\nThese lines from Anderson have clarified any doubts regarding this question. The answer is fairly obvious.\n\nOther characteristic pathologic feature of CNS in AIDS are :\n\nDiffitse and focal spongiform changes\nVascular myelopathy of post column of spinal cord\nMajor cells affected are macrophages and monocytes\nMost characteristic finding is chronic inflammatory reaction with widely distributed infiltrates of microglial nodules.', 'role': 'assistant'}]