This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of lipid, Subject name: Biochemistry
[{'content': 'Hyperlipidemias are treated by administering the following vitamin in megadoses \nSelect and explain. \nA. B12, B. Folate, C. Thiamine, D. Niacin', 'role': 'user'}, {'content': 'Answer: D \nExplanation: High doses of niacin are effective in lowering serum triglyceride, low-density lipoprotein, and lipoprotein-a levels and in elevating high-density lipoprotein levels. In high doses, Niacin causes dilatation of blood vessels and flushing, along with skin irritation. Intakes of both nicotinic acid and nicotinamide in excess of 500 mg/d also cause liver damage.Harper 30th edition Pg: 557', 'role': 'assistant'}]