This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'Which of the following suggests that a paicular case of hepatitis B is highly infective? \nSelect and explain. \nA. HbsAg +ve, B. HBsAg + HBeAg, C. Anti HbsAg, D. Anti HbeAg', 'role': 'user'}, {'content': "Answer: B \nExplanation: HBsAg in the serum is the first evidence of infection, HBeAg indicates viral replication and infectivity. Patients who are HBsAg and HBeAg positive indicates that they are highly infective. Anti HBsAg appear in individuals after clearence of HBsAg and is also present in individuals after successful vaccination. Reference: Harrison's Principles of Internal Medicine 18th edition chapter 304.", 'role': 'assistant'}]