This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': 'A lady has history of previous child birth with neural tube defect. What is the dose of folic acid to be given to prevent to neural tube defect in this child \nSelect and explain. \nA. 4000 mcg in periconceptional period, B. 400 mg after confirmation of pregnancy, C. 400 mg in periconceptional period, D. 4000 mcg in 1st / 2nd trimester.', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Dose of folic acid for primary prevention is 400 mcg / day\nDose of folic acid for secondary prevention (prevoius child affected with neural tube defect) is 4000 mcg / day started in periconception period = 1 month before to 3 months after conception.', 'role': 'assistant'}]