This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Acetyl CoA carboxylase requires which vitamin for function: \nSelect and explain. \nA. Thiamin, B. Riboflavin, C. Biotin, D. Niacin', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Bicarbonate as a source of CO2 is required in the initial reaction for the carboxylation of acetyl-CoA to malonyl-CoA in the presence of ATP and acetyl-CoA carboxylase. Acetyl-CoA carboxylase has a requirement for the B vitamin biotin. The enzyme is a multienzyme protein containing a variable number of identical subunits, each containing biotin, biotin carboxylase, biotin carboxyl carrier protein, and transcarboxylase, as well as a regulatory allosteric site. Ref: Harper 28th edition, chapter 23.', 'role': 'assistant'}]