This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: FMGE 2017, Subject name: Orthopaedics
[{'content': 'Which of the following is the management for postmenopausal women with osteoporosis: \nSelect and explain. \nA. Raloxifene, B. Tamoxifen, C. Bisphosphonates, D. Calcitonin', 'role': 'user'}, {'content': "Answer: C \nExplanation: DOC for osteoporosis is Bisphosphonates. It's mechanism of action is inhibition of osteoclast. Bisphosphonates are considered as first-line medication for reduction of fracture risk in post-menopausal women*. Calcitonin can also be used for osteoporosis& it acts by inhibiting osteoclast. Raloxifene and tamoxifen are selective estrogen- receptor modulators (SERMs) which is used to reduce the risk of breast cancer in high risk people and also used to prevent and treat osteoporosis in post-menopausal women. But it is less preferred than bisphosphonates.", 'role': 'assistant'}]