This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Growth and development, Subject name: Pediatrics
[{'content': "The following karyotype is suggestive of which disorder? \nSelect and explain. \nA. Patau syndrome, B. Edward's syndrome, C. Alagile syndrome, D. William's syndrome", 'role': 'user'}, {'content': 'Answer: A \nExplanation: The above karyotype is suggestive of patau syndrome: Trisomy 13 Clinical features of Trisomy 13/Patau syndrome Cardiac defects (Ventricular septal defect/atrial septal defects/patent ductus aeriosus) Microcephaly, Microphthalmia Cleft lip/palate Developmental delay Ocular hypotelorism Holoprosencephaly Thin posterior ribs (missing ribs) Renal abnormalities Polydactyly with flexed fingers Polycystic kidneys Scalp defects(aplasia cutis) Ref: Nelson textbook of pediatrics 21st edition pgno: 659', 'role': 'assistant'}]