This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pharmacology
[{'content': 'Which of the following is serious adverse effects seen with Zoledronate \nSelect and explain. \nA. Acute renal failure, B. Ventricular fibrillation, C. Peptic ulcer, D. Anterior uveitis', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Refer Goodman Gilman 12/e p 1296 The serious adverse effects noted with most of bisphoshonates is osteonecrosis of jaw bone Zoledronate can cause serious side effects as Nephrotoxicity and renal failure', 'role': 'assistant'}]