This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Steroid resistant nephritic syndrome is caused by mutation in which of the following? \nSelect and explain. \nA. Nephrin, B. Alpha-actinin-4, C. Podocin, D. Transient Receptor Potential 6', 'role': 'user'}, {'content': 'Answer: C \nExplanation: A mutation in the Nephrin (NPHS1) gene causes a hereditary form of congenital nephrotic syndrome with minimal change glomerular morphology whereas mutations in NPHS2 encoding for podocin results in steroid resistant nephrotic syndrome. Ref: Robbins 7Th Ed Page 981, 983.', 'role': 'assistant'}]