This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Skin
[{'content': 'Most common association with Acanthosis nigricans ? \nSelect and explain. \nA. Hypeension, B. DM, C. Obesity, D. Hypothyroidism', 'role': 'user'}, {'content': "Answer: C \nExplanation: Ans. is 'c' i.e., Obesity Acanthosis nigricans is a brown to black, velvety hyperpigmentation of the skin. It is usually found in body folds, such as posterior & lateral folds of neck, axilla, groin, umblicus, forehead. It typically occurs in individuals younger than 40 years of age. Histopathologically papillomatosis is characteristically seen; however, there is no hypermelanosis and there is only mild acanthosis, if present. It is associated with : Obesity (most common) Endocrinopathies --> Hypothyroidism, hypehyroidism, insuline resistance diabetes, Cushing's disease, PCOD, Bloom syndrome. Internal malignancy --> Gastric adenocarcinoma.", 'role': 'assistant'}]