This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Other disorders of bone, Subject name: Pediatrics
[{'content': 'Eteplirsen has been recently FDA approved for the treatment of \nSelect and explain. \nA. Duchenne muscular dystrophy, B. Spinal muscular atrophy, C. SSPE, D. AML', 'role': 'user'}, {'content': "Answer: A \nExplanation: Duchenne muscular dystrophy: MC hereditary neuromuscular disease in children. X-linked recessive deletion of dystrophin gene ( Xp 21)- one of the largest gene C/F: More common in males. Family history present Pseudohyperophy of calf muscles Cardiac involvement Recurrent respiratory infection Proximal muscle weakness in limbs Intellectual disability 'GOWER SIGN'is positive- Gowers' sign indicates weakness of the proximal muscles, esp of the lower limb. Mx- Phase 3 trials have shown benefits from ETEPLIRSEN - FDA APPROVED", 'role': 'assistant'}]