This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Tuberculosis of Bone and Joints, Subject name: Orthopaedics
[{'content': 'Tuberculosis of spine best diagnostic modality is: \nSelect and explain. \nA. Clinical, B. X-ray, C. MRI, D. CT guided biopsy', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Tissue diagnosis is always preferred over any radiological diagnosis hence CT guided biopsy to obtain tissue and then fuher investigations to grow the organisms is the preferred approach. MRI is best Radiological investigation But best investigation overall for infections or tumors is always biopsy.', 'role': 'assistant'}]