This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'Which of the following drugs is effective against HIV with Y181C mutation? \nSelect and explain. \nA. Festinavir, B. Lersivirine, C. Elvitegravir, D. Dolutegravir', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Lersivirine\nFestinavir is a NRTI shown to be effective in adefovir and tenofovir resistance\nLersivirine is a NNRTI effective against HIV with Y181C mutation\nElvitegravir is a integrase inhibitor used for initial / naïve treatment\nDolutegravir is a integrase inhibitor approved for raltegravir-resistant infections', 'role': 'assistant'}]