This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'In pemphigus, autoantibodies are directed against which of the following structures? \nSelect and explain. \nA. Acetylcholine receptor, B. Sarcomere, C. Epidermis, D. Thyroid follicle', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Pemphigus is an autoimmune disease wherein autoantibodies against epidermis cells are produced. Histologically, a phenomenon called acantholysis, wherein epidermal cells appear to detach and separate from each other, is observed.', 'role': 'assistant'}]