This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Targeted Anticancer Drugs and Immunosuppressants, Subject name: Pharmacology
[{'content': 'A 50-year-old female with rheumatoid ahritis is being considered for infliximab therapy. Which of the following tests should be performed before beginning treatment? \nSelect and explain. \nA. Liver function tests, B. PPD skin test, C. Pulmonary function tests, D. Visual examination', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Infliximab is a monoclonal antibody targeting TNF-a. It is commonly used to treat moderate to severe rheumatoid ahritis paicularly in patients who do not respond to methotrexate therapy. TNF-a inhibitors can lead to reactivation of latent tuberculosis due to TNF-a inhibitor action. All patients being considered for TNF-a inhibitor therapy should therefore have a baseline PPD skin test to screen for latent tuberculosis.', 'role': 'assistant'}]