This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'The paradoxical response of GH release to TRH is seen in - \nSelect and explain. \nA. Prolactinoma, B. Acromegaly, C. Malnutrition, D. Pitutary adenoma', 'role': 'user'}, {'content': 'Answer: B \nExplanation: TRH stimulates the secretion of prolactin as well as TSH,\nNormally it does not affect growth hormone secretion but in acromegaly TRH induced growth hormonal stimulation Occurs. \n\nNote:\n"In prolactinomas paradoxical response of TRH to prolactin occurs".\nIn normal individuals,\nTRH stimulates prolactin release\nWhere as in prolactinomas\nThere is little or no rise in prolactin in response to TRH.', 'role': 'assistant'}]