This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'Which one of the following clinical signs is not seen in ophthalmic Graves’disease? \nSelect and explain. \nA. Lid retraction, B. Frequent blinking, C. Poor convergence, D. Upper lid “lag” on down gaze', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Manifestations of Graves’ disease:\n1.Diffuse hyperfunctioning goiter—bruit over gland.\n2. Graves’ ophthalmopathy—inflammatory infiltrate of orbital contents, exclusive of globe, with lymphocytes, mast\ncells, and plasma cells.\nIt has two components—\n(a) spastic—stare, lid lag, lid retraction,\n(b) mechanical—proptosis, ophthalmoplegia, congestiveoculopathy (chemosis, conjunctivitis, periorbital swelling), corneal ulceration, optic neuritis, optic atrophy.\nDermatopathy—thickening of dermis, which is infiltrated with lymphocytes and with hydrophilic, metachromatically staining mucopolysaccharides. Dermatopathy usually occurs over dorsum of legs or feet (localized or pretibial myxedema). It is a late phenomenon but not a manifestation of hypothyroidism,\nskin—thickened, Peau d’orange appearance, pruritic, hyperpigmented, nonpitting edema, and thyroid acropathy (clubbing of fingers and toes with bony changes may accompany the dermal changes).', 'role': 'assistant'}]