This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Transcription, Subject name: Biochemistry
[{'content': 'Which of the following does not need a primer ? \nSelect and explain. \nA. DNA Polymerase I, B. RNA Polymerase, C. DNA Polymerase II, D. DNA Polymerase III', 'role': 'user'}, {'content': "Answer: B \nExplanation: DNA Polymerase needs RNA primer, which is synthesized by Primase. RNA Polymerase Doesn't need a primer as RNA Polymerases have the ability to initiate synthesis de novo. No proof reading activity DNA dependent RNA Polymerase Shine dalgarno sequence is recognized by protein synthesizing machinery i.e. Ribosome", 'role': 'assistant'}]