This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy, Subject name: Pharmacology
[{'content': 'Which of the following is a radioprotector \nSelect and explain. \nA. Colony stimulating factor, B. Cisplatin, C. Amifostine, D. Methotrexate', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Amifostine:- It is an organic thiophosphate which on activation by alkaline phosphatase acts as a cytoprotective against cancer chemotherapy and radiotherapy. Uses:- It is paicularly used for prophylaxis of cisplatin induced neuro/nephrotoxicity, and radiotherapy related xerostomia. Adverse effects:- Sho term side effects of amifostine are nausea, vomiting, hypotension and infusion related reaction. Delayed adverse effect is hypocalcaemia. Ref:- kd tripathi; pg num:-876', 'role': 'assistant'}]