This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Oesophagus, Subject name: Surgery
[{'content': 'Endoscopic treatment of leiomyoma of esophagus is contraindicated due to: \nSelect and explain. \nA. Infection, B. Chances of dissemination, C. Perforation, D. Perforation and dissemination', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans. (c) PerforationRef: Shackelford 7th Edition, Pages 518-520* Leiomyoma endoscopic biopsy or surgery is not advised due to risk of perforation', 'role': 'assistant'}]