This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pharmacology
[{'content': 'The following drugs have Significant drug interactions with digoxin except. \nSelect and explain. \nA. Cholestyramine, B. Thiazide diuretics, C. Quinidine, D. Amlodipine', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Amlodipine is a calcium channel blocker. Digoxin cause an increase in accumulation of intracellular Calcium. Hence there is no significant drug interaction with CCBS (REF.Essentials of medical pharmacology KD TRIPATHI 8th ed.)', 'role': 'assistant'}]