This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Which of the following antimalarial agents is most commonly associated with acute hemolytic reaction in patients with glucose–6–phosphate dehydrogenase deficiency \nSelect and explain. \nA. Chloroquine, B. Clindamycin, C. Mefloquine, D. Primaquine', 'role': 'user'}, {'content': 'Answer: D \nExplanation: None', 'role': 'assistant'}]