This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: mycology, Subject name: Microbiology
[{'content': 'A farmer presents with multiple discharging sinuses in the leg not responding to antibiotics. Most likely diagnosis is \nSelect and explain. \nA. Madurella, B. Actinomycetoma, C. Nocardia, D. Sporothrix', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Actinomycotic mycetoma usually respond well to sulphonamides and antibiotics, but mycotic mycetoma may require amputation. Sporothrix causes sporotrichosis is a nodular ulcerating disease of the skin and subcutaneous disease. Ref: Textbook of Microbiology, Ananthanarayan and Paniker; 9th edition', 'role': 'assistant'}]