This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pharmacology
[{'content': 'The following that have significant drug interactions with digoxin except \nSelect and explain. \nA. Cholestyramine, B. Thiazide diuretics, C. Quinidine, D. Amlodipine', 'role': 'user'}, {'content': 'Answer: D \nExplanation: (Ref KDT 6/e p499) Cholestyramine inhibits intestinalabsorption of digoxin. Thiazides result in hypokalemia and thus may precipitate digitalis toxicity by pharmacodynamic interaction. Quinidine and verapamil reduces the excretion of digoxin and thus may precipitate toxicity (pharmacokinetic interaction).', 'role': 'assistant'}]