This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Which of the following is ultrastructural feature of irreversible cell injury? September 2010 \nSelect and explain. \nA. Formation of phagolysosomes, B. Formation of amorphous densities in the mitochondrial matrix, C. Formation of blebs in plasma membrane, D. Detachment of ribosomes from rough', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans. B: Formation of amorphous densities in the mitochondrial matrixIrreversible cell injuryAfter the initiation of irreversible death, the cell and its organelles sta to disintegrate, leading to rupture of the cells.Gradually, the cytotoxic edema stas to resolve and interstitial edema develops as the cell membranes disintegrate and the intracellular components become extracellular.This results in increased Brownian water motion and marked reduction in diffusion restriction.The neuronal death result in reduction of its markers (NAA)', 'role': 'assistant'}]