This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Interleukin secreted by macrophages, stimulating lymphocytes is - \nSelect and explain. \nA. INF alpha, B. TNF alpha, C. IL-1, D. IL-6', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Interleukin -I o Also known as leucocyte activating factor (LAF) or B cell activating factor (BAF). Mainly secreted by macrophages and monocytes; and epithelial cells. Other sources are B-lymphocytes, fibroblasts and Endothelial cells. o Immunological effects of IL-1 Activation of T cells for the production of IL - 2. B cell proliferation and antibody synthesis Neutrophil chemotaxis and increased PMN release from bone marrow. Increases body temperature (impoant endogenous pyrogen). Bone marrow cell proliferation Induction of acute phase protein.', 'role': 'assistant'}]