This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Pharmacology
[{'content': 'The longest acting antihistaminic is \nSelect and explain. \nA. Terfenadine, B. Astemizole, C. Fexofenadine, D. Cetrizine', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Terfenadine is a prodrug broken down to fexofenadine.so long duration of action followed by astemizole Ref: Goodman Gillman 12th ed.Pg 924.', 'role': 'assistant'}]