This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Vitamins and Minerals, Subject name: Biochemistry
[{'content': "Casal's paint necklace is seen in? \nSelect and explain. \nA. Lichen planus, B. Pellagra, C. Pernicious anemia, D. SLE", 'role': 'user'}, {'content': 'Answer: B \nExplanation: Pellagra Etiology: Dietary deficiency of nicotinic acid or its precursor tryptophan. People with staple diet - maize and Jowar. Maize is poor source of both nicotinic acid and tryptophan and a pa of nicotinic acid is in a bound form that is not assimilated in GIT. Jowar-has high content of leucine.Imbalance between leucine and other related amino acids interferes with conversion of tryptophan to nicotinic acid. Malabsorption Drugs like INH, 5FU, and 6-mercaptopurine. Carcinoid syndrome C/f: Middle aged persons Pellagra:- (Dermatitis,Dementia,Diarrhea,Death) T/t: Niacinamide 300-500mg/day orally in divided doses.', 'role': 'assistant'}]