This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
[{'content': 'Which of the following statement about carcinoid of appendix is NOT TRUE? \nSelect and explain. \nA. Arises from argentaffin tissue, B. Cells express S-100, C. Frequently metastasize, D. Common at the tip', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Remember these points about carcinoid tumour of appendix Carcinoid tumors are neuroendocrine tumors arising in the argentaffin tissue (kulchitsky cells of crypts of lieberkuhn) They frequently contain sustentacular cells that express S -100 These tumors occur in any pa of the appendix but most common site is distal third i.e. tip of appendix Unlike carcinoid tumors arising in other pa of the GIT it rarely gives rise to metastasis. Ref: Sabiston 18/e, Page 1345; Schwaz 9/e, Page 1088; Bailey & Love 25/e, Page 1217.', 'role': 'assistant'}]