This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Mycobacterial Diseases (TB, Leprosy and MAC), Subject name: Pharmacology
[{'content': 'Which anti-tubercular drug combination is safer in a patient who develops hepatitis while on ATT? \nSelect and explain. \nA. Streptomycin + Isoniazid, B. Streptomycin + Ethambutol, C. Ethambutol + Isoniazid, D. Ethambutol + Rifampicin', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Streptomycin and Ethambutol are the only antitubercular drugs which have no hepatotoxicity thus are safer in a patient who develops hepatitis while on ATT as they dont have hepatic metabolism and are excreted by kidneys only. IMPOANT POINTS ABOUT FIRST LINE ATT: Drug Action Hepatotoxic Bacteria Inhibited Isoniazid CIDAL Yes Both Rifampicin CIDAL Yes Both Pyrazinamide CIDAL Yes Intracellular Ethambutol STATIC No Both Streptomycin CIDAL No Extracellular', 'role': 'assistant'}]