This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'True statement about Vitamin k is: \nSelect and explain. \nA. Vitamin K is water soluble, B. Vitamin K is essential for Fitzgerald factor, C. Vitamin K deficiency leads to thrombosis and pulmonary embolism, D. Vitamin K affects bone health by activating proteins that bind calcium', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ref. Guyton. 13th edition. Page. 490\nVitamin K\n\nVitamin K is a cofactor for the synthesis of blood coagulation Factors II, VII, IX and X, and inhibitors such as Protein C and S and bone matrix protein.\nIts active form is a coenzyme in the glutamic acid carboxylation.\nVitamin K-dependent factors form enzymatic complexes with calcium and membrane phospholipids.\nThe insufficiency of gamma glutamic carboxylation impairs the hemostatic function.\nHereditary deficiencies, antibiotics and oral anticoagulants, decrease the capacity of complex formation giving way to hemorrhage or thrombosis, or bone mass disturbances which are easily treated with administration of Vitamin K.\nThe main causes of Vitamin K deficiency are lack of hepatic storage in newborns, liver insufficiency, malabsorption, dietetic deficiency, therapy with the antibiotics and coumarin administration', 'role': 'assistant'}]