This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
[{'content': 'What is the basic nature of Prion? \nSelect and explain. \nA. DNA, B. RNA, C. Protein, D. Polysacchride', 'role': 'user'}, {'content': "Answer: C \nExplanation: Prions are proteinaceous and infectious in nature. The cellular form of the prion protein (PrPc) is encoded by the host's chromosomal DNA. PrPc is a sialoglycoprotein with a molecular weight of 33,000-35,000 and a high content of alpha helical secondary structure that is sensitive to proteases and soluble in detergent. PrPc is expressed on the surface of neurons a glycosylphosphatidyl inositol anchor in both infected and uninfected brains. Kuru, Creutzfeldt-Jakob disease (CJD), Gerstmann-Straussler-Scheinker disease, and fatal familial insomnia are prion mediated diseases in humans. Ref: Jawetz, Melnick, & Adelberg's Medical Microbiology, 25th Edition, Chapter 1", 'role': 'assistant'}]