This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Interleukin secreted by macrophages, stimulating lymphocytes is \nSelect and explain. \nA. IFN alpha, B. TNF alpha, C. IL-1, D. IL-6', 'role': 'user'}, {'content': 'Answer: C \nExplanation: IL1> IL6\n\nMacrophages release IL – 1 which stimulates the T – helper cells.\nThe T – cells in response proliferate and release IL – 2 which in turn further stimulates T – cell proliferation and B cell proliferation and differentiation into plasma cells.\nPlease note that even IL-6 (produced by macrophages) acts on late stages of B cell differentiation enhancing antibody formation. Still, IL-1 being the most important cytokine having systemic effects of inflammation has been chosen as the answer here in preference to IL-6.', 'role': 'assistant'}]