This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'True about fluoroquinolones is: \nSelect and explain. \nA. Ciprofloxacin is the drug of choice for Anthrax., B. Ciprofloxacin and levofloxacin are the only fluoroquinolones effective against pseudomonas., C. First generation has a narrow spectrum of action., D. All of the above.', 'role': 'user'}, {'content': 'Answer: D \nExplanation: First generation drugs like norfloxacin have narrow spectrum. The concentration of\xa0norfloxacin reached in urine is bactericidal, thus it can be used for UTI but it is not effective for systemic use.\xa0\xa0\n\nSecond-generation drugs like ciprofloxacin and ofloxacin are effective against gonorrhoea and other gram-negative organisms including pseudomonas.\xa0Ciprofloxacin is the drug of choice for prophylaxis and treatment of anthrax and for\xa0 prophylaxis of meningococcal meningitis.\xa0\nCiprofloxacin and levofloxacin are the only fluoroquinolones effective against Pseudomonas.', 'role': 'assistant'}]