This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.V.S., Subject name: Pediatrics
[{'content': 'Double arch of aorta is seen in: \nSelect and explain. \nA. CATCH22, B. Di George syndrome, C. Velo cardiofacial syndrome, D. All of the above', 'role': 'user'}, {'content': "Answer: D \nExplanation: d. All of above(Ref: Nelson's 20/e p 2211-2217, Ghai 8/e p 420-423)Double aortic archIt is associated with a chromosome 22q11 deletion in approximately 20% of patients22q11 deletion is responsible for DiGeorge, velocardiofacial, and conotruncal anomaly face syndromes, which are often referred to using the unified terms CATCH-22 syndromeIt is also associated with VACTERL (vertebral, anal, cardiac, tracheal, esophageal, renal, and limb abnormalities) orCHARGE (posterior coloboma, heart defect, choanal atresia, retardation, genital, and ear) associations.Previously classified as: (now considered part of same spectrum).Di-George syndrome (thymic hypoplasia, diminished T-cell immunity, parathyroid hypoplasia with hypocalcemia) andVelocardiofacialQ syndrome (congenital heart disease, dysmorphism, developmental delay).", 'role': 'assistant'}]