This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Glutathione peroxidase which protect erythrocytes against hemolysis contain the following element: \nSelect and explain. \nA. Chromium, B. Manganese, C. Zinc, D. Selenium', 'role': 'user'}, {'content': "Answer: D \nExplanation: In red blood cells, the pentose phosphate pathway is the sole source of NADPH for the reduction of oxidized glutathione. Reduced glutathione removes H2O2 in a reaction catalyzed by glutathione peroxidase, an enzyme that contains the selenium analog of cysteine (selenocysteine) at the active site. The reaction is impoant since accumulation of H2O2 may decrease the lifespan of the erythrocyte by causing oxidative damage to the cell membrane, leading to hemolysis. Ref: Bender D.A., Mayes P.A. (2011). Chapter 21. The Pentose Phosphate Pathway & Other Pathways of Hexose Metabolism. In D.A. Bender, K.M. Botham, P.A. Weil, P.J. Kennelly, R.K. Murray, V.W. Rodwell (Eds), Harper's Illustrated Biochemistry, 29e.", 'role': 'assistant'}]