This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Infection, Subject name: Medicine
[{'content': 'Which of the following can be used as a diagnostic modality for herpes labialis \nSelect and explain. \nA. Tzanck smear, B. Culture, C. Gram stain under microscope, D. PCR assay', 'role': 'user'}, {'content': "Answer: D \nExplanation: PCR finds the genetic material (DNA) of the HSV virus. This test can tell the difference between HSV-1 and HSV-2. Using the PCR test on skin sores isn't common. PCR is used mainly for testing spinal fluid in rare cases when herpes may have caused an infection in or around the brain. Antibody tests. Serologic tests are often used to detect HSV because they can differentiate between HSV-1 and HSV-2. There is an FDA-approved point-of-care test called POCkit that gives results from capillary blood or serum during an office visit. These tests are 80% to 98% sensitive and more than 96% specific. Ref Harrison20th edition pg ,977", 'role': 'assistant'}]