This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Vitamins and Minerals, Subject name: Biochemistry
[{'content': 'Deficiency of which of the following vitamins leads to lactic acidosis? \nSelect and explain. \nA. Riboflavin, B. Thiamine, C. Niacin, D. Pantothenic acid', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Thiamine is needed for the conversion of pyruvate to acetyl-CoA. In the absence of thiamine, pyruvate is channeled to lactate leading accumulation of L-lactate.', 'role': 'assistant'}]