This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Pathology
[{'content': "Characteristic feature of Goodpasture's syndrome \nSelect and explain. \nA. Lumpy-bumpy deposits on immunofluorescence, B. Serum antibodies against alpha 3 NC1 domain of collagen - IV, C. Serum antibodies against alpha 1 NCI domain of collagen III, D. Anti DNAse antibodies positive", 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans. (b) Serum antibodies against alpha 3 NC1 domain of collagen - IV(Ref: Robbins 9th/pg 912-913)Goodpasture syndromeIt is type 1 RPGN & a type II hypersensitivity reaction.It is characterized by serum antibodies against alpha 3 NC1 domain of collagen - IV.This shows linear GBM fluorescence, while all other Glomerulonephritis, which are type 3 Hypersensitivity reactions show granular immune deposits.', 'role': 'assistant'}]