This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Pathology
[{'content': 'In high myopia which of the following is seen? \nSelect and explain. \nA. Uveitis, B. Chorioretinal degeneration, C. Papillitis, D. Retinal. Hemorrhages', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Steroid-induced glaucoma Secondary open angle glaucoma TheoriesGlycosaminoglycans theory- Steroids inhibits the release of hydrolases -GAG in trabecular meshwork cannot depolymerize and retain water in ECS - narrowing of trabecular spaces and decrease in aqueous humor outflow Endothelial cell theory- Steroids suppress the phagocytic activity of endothelial cells - collection of debris in the trabecular meshwork - decreasing in aqueous outflow PG theory- Steroids inhibit the synthesis of PGE and PGF - decrease in aqueous outflow facility & increase in IOP Features - develops following weeks of topical therapy with strong steroids and months of therapy with weak steroids Treatment - discontinuation of steroids ; 0.5% timolol maleate ; filtration surgery (Refer: AH Khurana, Comprehensive Textbook of Ophthalmology,5thedition, pg no: 32-36)', 'role': 'assistant'}]