This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Which of the following is associated with > 20% risk of chromosomal anomalies: \nSelect and explain. \nA. Omphalocele, B. Cleft palate, C. Cleft lip, D. Spina bifida', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Omphalocele', 'role': 'assistant'}]