This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'All are true about thymus, EXCEPT: \nSelect and explain. \nA. Derived from third and fouh pharyngeal pouch, B. Located in the anterior mediastinum, C. It is composed of epithelial and stromal cells, D. The medulla of thymus contains 85 % of the lymphoid cells', 'role': 'user'}, {'content': 'Answer: D \nExplanation: THYMUS: Derived from the third and fouh pharyngeal pouches Located in the anterior mediastinum. Composed of epithelial and stromal cells derived from the pharyngeal pouch and lymphoid precursors derived from mesodermal cells. It is the site to which bone marrow precursors migrate to complete their differentiation. It has coex and the medulla. The coex contains 85% of the lymphoid cells, and the medulla contains 15%. Thymic abnormalities are very rare. If the thymus does not develop properly, severe immunodeficiency is seen (e.g., DiGeorge syndrome). If a lymphoid cell within the thymus becomes neoplastic, it is a lymphoma. The majority of lymphoid tumors that develop in the thymus are precursor T cell lymphoblastic lymphoma Rare B cell neoplasm in the thymus is mediastinal (thymic) B cell lymphoma Ref: Harrison, E-18, Chapter e-20', 'role': 'assistant'}]