This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Virology, Subject name: Microbiology
[{'content': 'Serological testing of patient shows HBsAg, IgM Anti-HBc and HBeAg positive . The patient has- \nSelect and explain. \nA. Chronic hepatitis B with low infectivity, B. Acute hepatitis B with high infectivity, C. Chronic hepatitis with high in fectivity, D. Acute on chronic hepatitis', 'role': 'user'}, {'content': 'Answer: B \nExplanation: HBs Ag is the first marker appear in the blood after infection. Anti HBc is the earliest antibody seen in blood. HBeAg indicates infectivity REF:MICROBIOLOGY ANANTHA NARAYANAN NINTH EDITION PAGE.546&547', 'role': 'assistant'}]