This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
[{'content': 'Which one of the following is detected by the antigen detection test used for the diagnosis of P. falciparum malaria - \nSelect and explain. \nA. Circum-sporozoite protein, B. Merozoite surface antigen, C. Histidine-Rich-Protein I (HRP-I), D. Histidine-Rich-Protein II (HRP-II)', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Antigen detection tests [Rapid diagnostic tests (RDTs) or Immunochromatographic tests (ICTs)\n\nRapid and simple but less sensitive, costly and may give false +ve in RA factor +ve cases\npLDH and Aldolase: Common to all Plasmodium species\nHRP-2 Ag detection: Specific for P.falciparum', 'role': 'assistant'}]