This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
[{'content': 'Hypercalcemia in the setting of squamous cell carcinoma esophagus is mainly due to: \nSelect and explain. \nA. Bone metastasis, B. Calcitonin excess, C. Parathormone excess, D. Parathormone related peptide secretion', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Hypercalcemia may occur in the absence of osseous metastases in squamous cell carcinoma esophagus, probably from parathormone-related peptide secreted by tumor cells. Ref:Harrison,E-18,P-765', 'role': 'assistant'}]