This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'A 30 weeks pregnant multigravida was found to have high BP, proteinuria and pedal edema. The antihypeensive can be used to control BP in this patient is: \nSelect and explain. \nA. Guanethidine, B. Labetalol, C. Atenolol, D. Captopril', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Labetalol is an alpha1-adrenergic blocker and a nonselective beta-adrenergic blocker and it is safe during pregnancy. The beta-blockade/alpha-blockade ratio is 7:1. It appears to lack teratogenicity and crosses the placenta in small amounts. Methyldopa, labetalol, or nifedipine are first-line antihypeensive agents in pregnancy. Among them, methyldopa is the first-line antihypeensive agent in pregnancy. Other antihypeensive medications used in pregnancy include metoprolol, prazosin, minoxidil, hydralazine, thiazide diuretics, and clonidine. Ref: Miller D.A. (2013). Chapter 26. Hypeension in Pregnancy. In A.H. DeCherney, L. Nathan, N. Laufer, A.S. Roman (Eds), CURRENT Diagnosis & Treatment: Obstetrics & Gynecology, 11e.', 'role': 'assistant'}]