This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': 'All of the following are true about childhood polycystic kidney disease, except – \nSelect and explain. \nA. Autosomal dominant, B. Pulmonary hypoplasia, C. Renal cyst present at birth, D. Hepatic fibrosis', 'role': 'user'}, {'content': "Answer: A \nExplanation: Childhood polycystic kidney disease \n\nChildhood polycystic kidney disease has autosomal recessive inheritance, therefore it is also known as autosomal recessive polycystic kidney disease.\nDefective gene is the PKHD1 (Polycystic Kidney and Hepatic Di8easel) which codes for a protein fibrocystin. Associations\nMaternal oligohydramnios\nPotter's syndrome\nPulmonary hypoplasia\nCongenital hepatic fibrosis\nHepatic cysts\nBiliary ductal atresia\n\nClinical features\n\nMajority of patients present during the first year of life (during infancy). However, sometimes patients may present later in life (in young adults).\nThe presentation is variable : -\n\n1. Renal\n\nEnlarged cystic kidney at birth.\nHypertension, Renal failure, Proteinuria.\n\n2. Respiratory\n\nRespiratory distress due to pulmonary hypoplasia.\n\n3. Hepatic\n\nHepatomegaly\nPortal hypertension → Esophageal varices, hypersplenism.", 'role': 'assistant'}]