This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Which of the following is required for unwinding of DNA - \nSelect and explain. \nA. Helicase, B. Primase, C. SSBP, D. Ligase', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Helicase proteinfunctionDNA polymerasesDeoxynucleotide polymerizationHelicasesProcessive unwinding of DNATopoisomerasesRelieve torsional strain that results from helicase induced unwindingDNA primaseInitiates synthesis of RNA primersSingle-strand binding proteinsPrevent premature reannealling of dsDNA DNA ligaseSeals the single strand nick between the nascent chain and Okazaki fragments on lagging strand", 'role': 'assistant'}]