This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'True about endodermal sinus tumors:a) Schiller duval bodies seenb) It is a benign tumourc) ↑HCGd) It is seen in young individualse) It is a malignant tumour \nSelect and explain. \nA. acd, B. bde, C. ade, D. ad', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Endodermal sinus tumor/Yolk sac tumor:\n• Endodermal sinus (yolk sac) tumour is third most common malignant germ cell tumour of ovary affecting mostly children or young women. (Age group 14–20 years.)\n• Tumour is highly malignant and is most rapidly growing tumour of whole body.\n• Histologically the pathognomic finding is Schiller - Duval bodies\xa0which is a single papilla lined by tumour cells with a central blood vessel.\n• Due to high rate of growth, tumour usually presents with acute abdomen.\n• Unilateral in 100% cases therefore biopsy of opposite ovary is contraindicated.\n• Almost all cases are associated with raised AFP and Alpha 1 antitrypsin.\n• It is the most deadly malignant ovarian germ cell tumor.\n• Treatment: Chemotherapy.\n• It has a high propensity for rapid growth, peritoneal spread and distant hematogenous dissemination to the lungs.', 'role': 'assistant'}]