This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Medicine
[{'content': 'Thiazides cause all the following side-effects except- \nSelect and explain. \nA. Hypercalcemia, B. Hypokalemia, C. Metabolic acidosis, D. Metabolic alkalosis', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Loop agents and distal convoluted tubule agents, such as the thiazides, produce hypokalemic, hypochloremic, metabolic alkalosis that responds to potassium chloride replacement. Carbonic anhydrase inhibitors produce less hypokalemia and volume depletion but commonly induce metabolic acidosis that is often symptomatic Ref Davidson 23rd edition pg 354', 'role': 'assistant'}]