This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Anatomy
[{'content': 'Mikulicz cell and Russell bodies are seen in \nSelect and explain. \nA. Rhinoscleroma, B. Rhinophyma, C. Rhinosporidiosis, D. Plasma cell disorder', 'role': 'user'}, {'content': "Answer: A \nExplanation: Granulomatous disease of the nose BacterialFungalUnspecified causeRhinoscleroma Syphilis TuberculosisLupusLeprosy RhinosporidiosisAspergillosis Mucormycosis CandidiasisHistoplasmosis Blastomycosis Wegner's granulomatosisNon healing midline granuloma Sarcoidosis Churg Strauss syndrome RhinoscleromaAgent - Klebsiella rhinoscleromatisSite - nose, nasopharynx, oropharynx, larynx, trachea, bronchi Atrophic stageFoul smelling purulent nasal dischargeGranulomatous stage Subdermal infiltration of lower pa of external nose & upper lip - woody feelRubbery nodules - Tapir nose Cicatricial stage Stenosis of nares Distoion of upper lip Adhesions of nose, nasopharynx, oropharynx Subglottic stenosisNose deformity - Hebra nose Soft palate deformity - Gothic arch deformity Diagnosis Biopsy - infiltration of submucosa with plasma cells, lymphocytes, eosinophils, Mikulicz cells ( large foam cells with central nucleus & vacuolated cytoplasm containing causative bacilli ) & Russell bodies(homogenous eosinophilic inclusion bodies found in plasma cells)The culture of the organism Treatment - Streptomycin (1g/day) & tetracycline (2g/day) for 4 - 6 weeks (Refer: PL Dhingra, Textbook of Ear, Nose, Throat, 6thedition, pg no: 156)", 'role': 'assistant'}]