This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.N.S, Subject name: Pharmacology
[{'content': 'Prolonged use of anticonvulsant drug can produce weight loss: \nSelect and explain. \nA. Gabapentin, B. Oxcarbazepine, C. Topiramate, D. Valproic acid', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans. C. TopiramateTopiramate is the newer class of antiepileptic drug which act via blockade of sodium channel, activation of GABA receptor and blockade of NMDA receptor. It is drug of choice for Lenox Gastaut syndrome. It can weight loss.', 'role': 'assistant'}]