This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Structure and function of protein, Subject name: Biochemistry
[{'content': 'Chaperone proteins play a role in \nSelect and explain. \nA. Protein folding, B. Protein misfolding, C. Denaturation, D. All the above', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Chaperone proteins paicipate in the folding of over half of all mammalian proteins. They can "rescue" unfolded proteins that have become thermodynamically trapped in a misfolded dead end by unfolding hydrophobic regions and providing a second chance to fold productively. Ex: Glutathione can reduce inappropriate disulfide bonds that may be formed upon exposure to oxidizing agents such as O2, hydrogen peroxide, or superoxide Reference: Explanation: Harper\'s Biochemistry; 30th edition; Chapter 5; proteins: higher Orders of Structure', 'role': 'assistant'}]