This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Disorders of Pubey, Subject name: Pediatrics
[{'content': 'In hypogonadotropic hypogonadism? \nSelect and explain. \nA. Both LH and FSH decreased, B. Both LH and FSH increased, C. LH increased and FSH decreased, D. LH decreased and FSH increased', 'role': 'user'}, {'content': 'Answer: A \nExplanation: - LH and FSH are decreased in hypogonadotropic hypogonadism. Hypogonadotropic hypogonadism: - Reversible - if its d/t to Chronic systemic illness (CKD, Chronic liver Disease) Severe malnutrition Endocrine causes (hypothyroidism, type 1 DM) - Permanent if its d/t Isolated delayed pubey - Genetic mutations - KAL 1 (Kallmann Syndrome), GnRH Receptor, DAX -1 gene - Syndromes- Prader Willi Syndrome, Laurence Moon Syndrome MPHD (multiple pituitary hormone disease) - Injury - Infiltration by tumors- Langerhan cell histiocytosis - Genetic - PROP1,LH - Malformations - Trauma', 'role': 'assistant'}]