This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti Microbial, Subject name: Pharmacology
[{'content': 'Jarisch - Herxheimer reaction are seen in syphilis With \nSelect and explain. \nA. Tetracyclines, B. Penicillines, C. Co-trimoxazole, D. Sulfonamides', 'role': 'user'}, {'content': 'Answer: B \nExplanation: (Penicillin) (657-KDT) (698-KDT 6th)Jerisch-Herxheimer reaction:- Penicillin injected in a syphilitic patient (particularly secondary syphilis) may produce shivering, fever myalgia, exacerbation of lesions, even vascular collapse. This is due to sudden release of spirochetal lytic products and lasts 12-72 hours. It does not recur and does not need interruption of therapy.Aspirin and sedation afford relief of symptoms.', 'role': 'assistant'}]