This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Medicine
[{'content': 'Which of the following is a poor prognostic factor in Acute Lymphoblastic Leukemia (ALL) - \nSelect and explain. \nA. Hyperdiploidy, B. t (9;22); t (4; 11), C. 2-8 years of age, D. WBC count < 50,000', 'role': 'user'}, {'content': 'Answer: B \nExplanation: The high risk indicators in ALL includes age below 1 year & above 10 year, male ,initial white cell count more than 50,000/mm^3, massive hepatomegaly & splenomegaly, prwsence of mediastinal mass & central nervous system leukaemia , mature Bcell as phenotype , hypodiploidy, t(9;22),t(4;11), t(8;14).Reference :Ghai essential pediatrics 8th edition pg no 601.', 'role': 'assistant'}]