This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunology, Subject name: Microbiology
[{'content': "Superantigens true is - \nSelect and explain. \nA. They bind to the left of the MHC, B. Needs to processed before presentation, C. They are presented by APC'S to T cells, D. Directly attached to lateral aspect of TCR b chain", 'role': 'user'}, {'content': 'Answer: D \nExplanation: Superantigens are a class of antigens that cause non-specific activation of T-cells resulting in polyclonal T cell activation and massive cytokine release. Superantigens bind first to the MHC Class II and then coordinate to the variable alpha or beta chain of T-cell Receptors . Reff: Ananthanarayan & Panikers textbook of microbiology 9th edition pg:90', 'role': 'assistant'}]