This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cells of epidermis, Subject name: Dental
[{'content': 'Which is antigen presenting cell in the epidermis that is required for the induction of allergic contact dermatitis is: \nSelect and explain. \nA. Fibroblasts, B. Keratinocytes, C. Langerhans cells, D. Melanocytes', 'role': 'user'}, {'content': "Answer: C \nExplanation: Langerhans' cell is a specialized antigen-presenting cell that help in antigen recognition and activation T cell mediated immune response. Functions - phagocytosis, antigen processing, antigen presentation, interaction with lymphocytes. Release IL-1 Langerhans cells are derived from mesoderm Langerhans cells are present in stratum spinosum Birbeck granules - rod or racquet shaped - contain Langerin Langerhans' cell decrease in (PSC) Psoriasis Sarcoidosis Contact dermatitis Langerhans' cell increase in - Langerhans Cell Histiocytosis", 'role': 'assistant'}]