This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Electrolyte, Subject name: Medicine
[{'content': 'In renal failure, metabolic acidosis is due to ? \nSelect and explain. \nA. Increased H" production, B. Loss of HCOf, C. Decreased ammonia synthesis, D. Use of diuretics', 'role': 'user'}, {'content': "Answer: C \nExplanation: Ans. is 'c' i.e., Decreased ammonia synthesis The predominant reason for metabolic acidosis in C.R.F. is decreased ammonia production.o Metabolic acidosis is a common disturbance in advanced chronic kidney' disease# The majority of patients can still acidly the urine but they'produce less ammonia and, therefore, cannot excrete the normal quantity of protons in combination with this urinary* buffer.", 'role': 'assistant'}]