This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'Lesch nyhan syndrome due fo- \nSelect and explain. \nA. HGPRT ase deficieny (complete), B. HGPRT ase deficiency (partial), C. Hexosaminidase deficiency (complete), D. Hexosaminidase deficiency (partial)', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. is \'a\' i.e., HGPRTase deficiency (complete) Lesch Nyhan disease (LND) o X-link recessive disorder o Defect in purine metabolism o complete Deficiency of HPRT enzyme o Manifest as hyperuricemia, intellectual disability", dystonic movement disorder like chorea-athetosis, spasticity, dysarthric speech. Partial deficiency in HPRT ---- (Keltey-Seegmiller syndrome) Iduronate sulfate sulfatase def. - Hunter syndrome o Hexosaminidase dediciency seen in Tay-sachs disease o Glucocerebrosidase def - Gaucher disease o <-L Iduronidase def. in Hurler syndrome', 'role': 'assistant'}]