This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolic disorders, Subject name: Pediatrics
[{'content': 'The gene for Wilson&;s disease is on \nSelect and explain. \nA. Long arm of Chromosome 13, B. Long arm of Chromosome 6, C. Sho arm of Chromosome 13, D. Sho arm of Chromosome 6', 'role': 'user'}, {'content': 'Answer: A \nExplanation: In Wilson&;s disease,the underlying defect lies in the long arm of chromosome 13 where there is a mutation in ATP7B gene,the normal hepatic copper- excreting gene.Eventually,capacity of hepatocytes to store copper is exceeded and copper is released into circulation which then gets deposited in extrahepatic tissues such as the brain eyes, and others. Reference:Textbook of pathology-Harsh Mohan,6th edition,page no:628', 'role': 'assistant'}]