This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Targeted Anticancer Drugs and Immunosuppressants, Subject name: Pharmacology
[{'content': "Ibrutinib drug is used in all except: \nSelect and explain. \nA. Mantle cell lymphoma, B. Chronic lymphocytic leukemia, C. Waldenstrom's macroglobulinemia, D. AML", 'role': 'user'}, {'content': "Answer: D \nExplanation: Bruton tyrosine kinase (BTK) is a validated target for B cell malignancies. BTK inhibitor ibrutinib was approved in: - Chronic lymphocytic leukaemia- Mantle cell lymphoma- Waldenstrom's macroglobulinemia NIB -drug ending with NIB are kinase inhibitor BRUT - Bruton's tyrosine kinase inhibitor", 'role': 'assistant'}]