This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Physiology
[{'content': 'Urinary metabolite of progesterone \nSelect and explain. \nA. Pregnanolone, B. Progestriol, C. 17-HydroxyPregnanolone, D. Pregnanediol', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Pregnanediol is most abundant plasma as well as urinary metabolite of progesterone. In plasma 80 % is bound to albumin and 18 % to coicosteroid binding globulin. Progesterone has sho half-life and in liver it is conveed to Pregnanediol and conjugated to glucoronic acid and excreted in urine. Ref: Ganong review of Medical physiology 22nd edition Pgno: 443', 'role': 'assistant'}]