This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Diet in Pregnancy, Subject name: Gynaecology & Obstetrics
[{'content': 'Neural tube defect is due to deficiency of - \nSelect and explain. \nA. Folate, B. Pyruvate, C. Cobalamine, D. Thiamine', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. is \'a\' i.e.. Folate "Folic acid supplementation can reduce the risk of NTDs, presumably by preventing nutritional deficiency and by overcoming disruptions in folate metabolism related to underlying genetic variation in folate-related genes. Folic acid may enhance cell proliferation for neural closure directly or it may be involved in the epigenetic regulation of expression of genes that control neural closure."', 'role': 'assistant'}]