This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of carbohydrate, Subject name: Biochemistry
[{'content': 'GAG affected in Sanfilippo syndromes is \nSelect and explain. \nA. Dermatan sulfate, B. Heparan sulfate, C. Keratan sulfate, D. Chondroitin sulfate', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Disease name Abbretion Enzyme Defective GaG(s) affected Symptoms Sanfilippo syndrome A MPS IIIA Heparan sulfate-N-sulfatase Heparan sulfate Delay in development, motor dysfunction Sanfilippo syndrome B MPS IIIB a-N-Acetylglucosaminidase Heparan sulfate As MPS IIIA Sanfilippo syndrome C MPS IIIC a-Glucosaminide N-acetyltransferase Heparan sulfate As MPS IIIA Sanfilippo syndrome D MPS IIID N-Acetylglucosamine 6-sulfatase Heparan sulfate As MPS IIIA Reference: Harper; 30th edition; Page no:639; Table: 50-8', 'role': 'assistant'}]