This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General anatomy, Subject name: Anatomy
[{'content': 'After I.V drug administration , elimination of a drug depends on \nSelect and explain. \nA. Volume of distribution, B. Clearance, C. Lipids solubility, D. All', 'role': 'user'}, {'content': 'Answer: D \nExplanation: elimination of drug depends on -volume of distribution -clearance Volume of distribution is more for high lipids solubility Ref-KDT 7/e p30-31', 'role': 'assistant'}]