This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Bleeding disorder, Subject name: Pathology
[{'content': 'The following test may be abnormal in DIC, except: \nSelect and explain. \nA. PT, B. APTT, C. D-dimer, D. Clot solubility', 'role': 'user'}, {'content': "Answer: D \nExplanation: Disseminated intravascular coagulation (DIC) acquired disorder characterised by: Widespread systemic activation of coagulation with formation of microthrombi in small blood vessels Bleeding diathesis secondary to depletion of coagulation factors and platelets Causes of DIC: Sepsis or severe infections Trauma especially of brain or crush injury Obstetric conditions: amniotic fluid embolism, abruptio placentae, septic aboion, eclampsia, intrauterine retention of dead foetus Disseminated solid cancers, acute promyelocytic leukemia Severe haemolytic transfusion reactions Thermal injury- heat stroke, extensive burns Snake bite e.g: Russell's viper7 Giant haemangioma (Kasabach-Merritt syndrome) C/F Brain - mc affected confusion , altered sensorium , dizziness , coma Hea - |CO / dyspnea Kidney - Acute tubular necrosis Lungs - Difficulty in breathing , hypoxemia Adrenal Gland - Hemorrhage - Waterhouse- friderichsen syndrome Lab findings- Anaemia and thrombocytopenia |LDH | Unconjugated bililrubin Peripheral Smear shows Shistiocytes Prolonged BT , PT and APTT FDP and D-dimer: Increased.", 'role': 'assistant'}]