This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Medicine
[{'content': 'Which type diabetes is HLA associated- \nSelect and explain. \nA. Type I diabetes, B. Type II diabetes, C. Malnutrition related type disease, D. Pregnancy related type diabetes', 'role': 'user'}, {'content': "Answer: A \nExplanation: The major susceptibility gene for type 1 DM is located in the HLA region on chromosome 6. Polymorphisms in the HLA complex account for 40-50% of the genetic risk of developing type 1 DM. Most individuals with type 1 DM have the HLA DR3 and/or DR4 haplotype. Refinements in genotyping of HLA loci have shown that the haplotypes DQA1*0301, DQB1*0302, and DQB1*0201 are most strongly associated with type 1 DM. Reference : page 2403 Harrison's Principles of Internal Medicine 19th edition", 'role': 'assistant'}]