This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
[{'content': 'High risk of malignancy is seen in? \nSelect and explain. \nA. Simple hyperplasia with atypia, B. Simple hyperplasia without atypia, C. Complex hyperplasia with atypia, D. Complex hyperplasia without atypia', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Answer is option3, complex hyperplasia with atypia Endometrial hyperplasia with atypia is the least common type of hyperplasia, but is the type most likely to progress to type 1 endometrial carcinoma (1-3) which accounts for 97% of uterine cancers, whereas simple hyperplasia rarely progresses to carcinoma. >', 'role': 'assistant'}]