This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Blood, Subject name: Pediatrics
[{'content': "A 10-year-old child with short stature pallor, multiple petechiae, and hypoplastic thumb has HB of 7 g %, normal reticulocyte count (1%), hematocrit 25%, and absolute neutrophil count 200/cu mm. The most likely diagnosis is \nSelect and explain. \nA. Fanconi's anemia, B. HIV bone morrow infection, C. Hypersplenism induced bicytopenia, D. Parvovirus B virus infection with transient erythro- blastopenia of childhood", 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. a (Fanconi\'s anemia) (Ref. Nelson Textbook of Pediatrics, 19th ed./Ch. 489)Neutropenia may be present with some viral infections, particularly parvovirus B19 infection; drug reactions; systemic lupus erythematosus; typhoid; brucellosis; and infiltrative diseases of the bone marrow, including lymphoma, leukemia, tuberculosis, and histoplasmosis.The rash of erythema infectiosum (fifth disease), which is caused by human parvovirus B19, primarily affects children 3 to 12 years old; it develops after fever has resolved as a bright blanchable erythema on the cheeks ("slapped cheeks") with perioral pallor.Educational point:# Earliest feature of Fanconi\'s anemia is pancytopenia.# Filgastrim is drug used in Rx of febrile neutropenia.', 'role': 'assistant'}]