This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'Amikacin (Amikin) is given to a client with E-coli infection. The nurse advises the client to report which of the following symptoms immediately? \nSelect and explain. \nA. Muscle pain., B. Constipation., C. Fatigue., D. Hearing loss', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Amikacin\xa0is an aminoglycoside. Side effects of this medication includes ototoxicity (Hearing\xa0loss), confusion, disorientation, gastrointestinal irritation, palpitations, blood pressure changes and nephrotoxicity.\n\nOptions A, B, and C are not related with the medication.', 'role': 'assistant'}]