This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Ophthalmology
[{'content': 'Familial retinoblastoma –a) Has autosomal recessive inheritanceb) More commonly bilateralc) Due to mutationd) More common than sporadic retinoblastomae) Poorer prognosis than sporadic type \nSelect and explain. \nA. ab, B. bce, C. acd, D. ace', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Hereditary retinoblastoma is less common than sporadic retinoblastoma and is inherited as autosomal dominant pattern.\nAll bilateral retinoblastoma are hereditary.\nHereditary retinoblastoma is due to inactivation of RB gene by two mutations.\nHereditary retinoblastoma patients may develop additional tumors in the pineal suprasellar or fourth ventricle region, and have a poor prognosis.', 'role': 'assistant'}]