This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunology, Subject name: Microbiology
[{'content': 'All are true regarding agammaglobulinemia except - \nSelect and explain. \nA. Loss of germinal centre in lymph node, B. Normal coical lymphocytes, C. Normal coical lymphocytes in paracoex and medulla, D. Decreased red pulp in spleen', 'role': 'user'}, {'content': 'Answer: B \nExplanation: In agammaglobulinemia all classes of immunoglobulins are grossly depleted in the serum. Tonsils & Adenoids are atrophic. Lymph node biopsy reveals depletion of cepls of bursa dependent areas. Plasma cells and germinal centres are absent even after antigenic stimulation. There is marked decrease in the poion of B cells in circulation. Ref: Ananthanarayan & Panikers textbook of microbiology 9th edition pg.no. : 171,172', 'role': 'assistant'}]