This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Histo Pathology, Subject name: Pathology
[{'content': 'Most significant contraindication for Fine Needle Aspiration biopsy (FNA) is: \nSelect and explain. \nA. Moribund state of the patient, B. Disseminated malignancy, C. Bleeding disorder, D. HIV positivity', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans: c. (Bleeding disorder)Ref: British Society for Clinical CytologyContraindication for FNA1. Uncorrected coagulopathies Anticoagulant therapy Intrinsic bleeding disorder2. Parasitic cysts - Chance of anaphylactic shock.3. Cough & respiratory infection - Contraindication for transthoracic FNA4. Carotid body tumour - May cause catecholamine release with potential risk of hypertensive crisis.', 'role': 'assistant'}]