This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Not true about thalidomide : \nSelect and explain. \nA. Causes phocomelia, B. Not tested in pregnant animals before introduction, C. Still has restricted clinical use, D. Has no antiangiogenesis action against tumour', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Thalidomide was banned in 1960 because of its teratogenic effect of phocomelia (seal-like limbs). It has anxiolytic, adjuvant analgesic/antipyretic properties and has been found to counteract cancer-associated cachexia.\nIts mechanism of action is by suppressing TNF and or by modulating IL-2.\nRecently it has been reintroduced as an antineoplastic drug due to its anti-angiogenesis action.', 'role': 'assistant'}]