This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
[{'content': 'Typhoid perforation occurs during \nSelect and explain. \nA. Ist week, B. 2nd week, C. 3rd week, D. 4th week', 'role': 'user'}, {'content': 'Answer: C \nExplanation: • Enteric fever is a potentially life - threatening systemic disease characterized by fever and abdominal pain.\n• It is caused by Salmonella typhi or paratyphi.\n• Typhoid is the MC cause of ileal perforation in tropical countries (India).\nPathology :\n• Ulceration and necrosis of ileocecal Peyer’s patches.\n• The ulcer is parallel to the long axis of the gut and is usually situated in the lower ileum (longitudinal ulcers).\n• Perforation of a typhoid ulcer usually occurs during the third week\xa0and is occasionally the first sign of the disease.\nClinical Features :\n• Fever and abdominal pain are hallmark symptoms.\n• Non-specific symptoms : Headache, cough, sweating, myalgia, arthralgia, fatigue.\n• Paralytic ileus is the MC complication\xa0of typhoid.\n• Intestinal hemorrhage (2nd MC)\xa0may be the leading symptom.', 'role': 'assistant'}]