This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endometriosis & H, Subject name: Gynaecology & Obstetrics
[{'content': 'Which of the following drugs used for endometriosis can cause increase in hepatic enzyme and adverse lipid profile? \nSelect and explain. \nA. OC pills, B. LNG IUD, C. GnRH analogues, D. Dienogest', 'role': 'user'}, {'content': 'Answer: A \nExplanation: All mentioned drugs are used for the treatment of endometriosis, their side effect profiles are as follows: OC pill (progesterone component) are associated with increase in LDL and decrease in HDL cholesterol, but estrogens have opposite effect. Cholestasis and cholestatic jaundice are occasional side effects of OC pills. LNG IUCD: intermenstrual bleeding, pelvic pain, ovarian cysts, headache GnRh analogues: hypoestrogenic side effects: hot flashes, osteoporosis, headaches Dienogest: irregular bleeding, headache, hot flushes, weight gain', 'role': 'assistant'}]