This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Features of Paget’s disease can be: \nSelect and explain. \nA. Affecting the skull generally leads to a progressive increase in circumference of the head. (osteoporosis circumscripta), B. Jigsaw puzzle appearance of the bone, C. Leontiasis ossea., D. All of the above.', 'role': 'user'}, {'content': 'Answer: D \nExplanation: None', 'role': 'assistant'}]