This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Dental
[{'content': 'Skeletal maturity is indicated by: \nSelect and explain. \nA. Carpals, B. Radius, Ulna, C. Both 1 and 2, D. None', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Various methods have been proposed for assessment of skeletal maturity. These include:\n\nChronological age\nPeak height velocity (PHV)\nDental age\nHand-wrist radiographs\nCervical vertebral maturation index (CVMI).\n\nFishman (1982) developed the system for the evaluation of skeletal maturity on a hand-wrist radiograph and investigated its association with craniofacial growth. He called it skeletal maturation assessment (SMA), which is based on skeletal maturity indicators.\nThe system uses only four stages of bone maturation:\n\nEpiphyseal widening of the phalanges\nOssiﬁcation of the adductor sesamoid of the thumb\nCapping of epiphyses over their diaphysis\nFusion of epiphyses and diaphysis.\n\nThese stages of bone formation are found at six anatomical sites located on the thumb, third ﬁnger, ﬁfth ﬁnger and radius.', 'role': 'assistant'}]