This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Baclofen acts as - \nSelect and explain. \nA. GABAA receptor agonist, B. GABAB receptor agonist, C. GABAA receptor antagonist, D. GABAB receptor antagonist', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., GABAB receptor agonist There are two types of GABA receptors. 1. GABAA receptor - Intrinsic ion channel --> increases Cl- conductance, blocked by bicuculline, facilatated by benzodiazepines. 2. GABAB receptor - G protein coupled receptor; hyperpolarizes neurones by increasing IC conductance and altering Ca' flux, bicuculline has no effect, blocked by saclofen. o Baclofen acts as an agonist on GABAB receptor.", 'role': 'assistant'}]