This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetics, Subject name: Pathology
[{'content': "A 20-year-old man is examined by a new family physician who discovers numerous pigmented patches and pedunculated skin tumors on his chest. Biopsy of a tumor discloses a benign neoplasm derived from Schwann cells. Neither the patient's father nor mother shows signs of this disease. The patient is at increased risk of developing which of the following malignant neoplasms? \nSelect and explain. \nA. Ganglioneuroma, B. Glioblastoma multiforme, C. Neurofibrosarcoma, D. Serous cystadenocarcinoma", 'role': 'user'}, {'content': 'Answer: C \nExplanation: One of the major complications of neurofibromatosis type 1 (NF1), occurring in 3% to 5% of patients, is the appearance of a neurofibrosarcoma in a neurofibroma. NF1 is also associated with an increased incidence of other neurogenic tumors, including meningioma, optic glioma, and pheochromocytoma. The other tumors listed are not associated with NF1.Diagnosis: Neurofibromatosis, type 1', 'role': 'assistant'}]