This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.N.S, Subject name: Pharmacology
[{'content': 'All are morphine effects EXCEPT: \nSelect and explain. \nA. Miosis, B. Delayed gastric emptying, C. Respiratory depression, D. Hyperalgesia', 'role': 'user'}, {'content': "Answer: D \nExplanation: (Ref: Goodman & Gillman's 14th ed. pg. 363-6* Effect of morphine is seen mainly at m-receptor. Effect on m-receptor depends on either supraspinal or spinal m- receptor.# Supraspinal effects: Physical dependence, euphoria, analgesia, sedation. (PEAS)# Spinal effects: Constipation, analgesia and respiratory depression. (CAR)* Effect of morphine at heart: No effect at usual dose but at high dose it can cause bradycardia and hypotension.* Effect of morphine at eye: No effect if applied locally. Miosis on systemic intake. Miosis can be worsened to pinpoint pupil upon systemic morphine toxicity.Note: Morphine causes analgesia. Hyperalgesia is one of thewithdrawal symptoms.", 'role': 'assistant'}]