This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'A cell cycle specific anticancer drug that acts mainly in the M phase of the cycle is: \nSelect and explain. \nA. Cisplatin, B. Etoposide, C. Methotrexate, D. Paclitaxel', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Vinca alkaloids (Vincristine, Vinblastine and Vinorelbine) and taxanes (Paclitaxel and Docetaxel) act on M-phase of the cell cycle.\nVinca alkaloids inhibit the formation whereas taxanes inhibit the breakdown of the mitotic spindles.', 'role': 'assistant'}]