This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti Microbial, Subject name: Pharmacology
[{'content': 'Mechanism of action of triazoles is: \nSelect and explain. \nA. Inhibit ergosterol synthesis, B. Inhibit mitotic spindle, C. Create pores in the membrane, D. Inhibit beta 1,3 glycan', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. (A) Inhibit ergosterol synthesis(Ref: Goodman and Gilman 13th/e p1091)Anti-fungal drug groupExampleMechanismPolyeneAmphotericin BCreate artificial pores in membrane by binding to ergosterolAzoles (Imidazole and triazoles)FluconazoleItraconazoleInhibit Lanosterol-14- alpha-demethylaseAllylaminesTerbinafineButenafineInhibit squalene epoxidaseAnti-metabolite5-FlucytosineInhibit DNA formationBenzofuranGriseofulvinBinds to tubulin and inhibit mitosisEchinocandinsCaspofungin MicafunginInhibit beta 1,3 glycan in fungal cell wall', 'role': 'assistant'}]