This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Surgery
[{'content': 'True about rectal Ca \nSelect and explain. \nA. MC type adenocarcinoma, B. Surgery is the treatment of choice, C. Surgical treatment indicated inspite of hepatic metastasis, D. APR done in lesions of upper zone', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Although rare, the incidence of anal squamous cell carcinoma (SCC) is rising, with a direct association with HPV infection, AIN and immunosuppression. Thus, high-risk groups are those infected with HPV (especially subtypes 16, 18, 31 or 33) Ref: Bailey & Love&;s Sho Practice of Surgery,E25,Page-1269', 'role': 'assistant'}]