This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'True about Trastuzumab are all except: \nSelect and explain. \nA. Better combination with paclitaxel, B. Used in metastatic breast cancer, C. Causes upregulation of HER2/neu, D. No bone marrow toxicity', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Causes upregulation of HER2/neu', 'role': 'assistant'}]