This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Target fibres are characteristically seen in a muscle biopsy of - \nSelect and explain. \nA. Dermatomyositis, B. Motor neuron disease, C. Myasthenia gravis, D. Drug induced myopathy', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Target fibers\n\nDuring denervation atrophy there is a cytoskeletal reorganization of some muscle cells, which results in a rounded zone of disorganized filaments in the centre of the fiber (target fiber).\nAmongst the given options only motor neuron disease can result in denervation of the muscle.', 'role': 'assistant'}]