This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'All of the following are metabolic effects of progesterone in normal pregnancy, EXCEPT: \nSelect and explain. \nA. It increases basal insulin levels, B. Norgestrel increase glucose tolerance, C. Stimulates lipoprotein lipase activity, D. Does not alter glucose tolerance', 'role': 'user'}, {'content': "Answer: B \nExplanation: Progesterone increases basal insulin levels and the rise in insulin after carbohydrate ingestion, but it does not normally alter glucose tolerance. However, long-term administration of more potent progestins, such as norgestrel, may decrease glucose tolerance. Progesterone stimulates lipoprotein lipase activity and seems to enhance fat deposition. Ref: Levin E.R., Hammes S.R. (2011). Chapter 40. Estrogens and Progestins. In L.L. Brunton, B.A. Chabner, B.C. Knollmann (Eds), Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e.", 'role': 'assistant'}]