This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
[{'content': 'The acrosome reaction occurs, when the sperm \nSelect and explain. \nA. Enters the uterine cavity, B. Comes in contact with zona pellucida, C. Penetrates corona radiata, D. Penetrates cell membrane of oocyte', 'role': 'user'}, {'content': 'Answer: B \nExplanation: None', 'role': 'assistant'}]