This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General obstetrics, Subject name: Anatomy
[{'content': 'Insulin resistance in pregnancy is because of: \nSelect and explain. \nA. Human placental lactogen, B. Progesterone, C. Estrogen, D. All the above', 'role': 'user'}, {'content': 'Answer: D \nExplanation: During pregnancy, insulin levels are increased because of increased insulin secretion as well as increase in insulin resistance due to number of contra insulin factors. These are Estrogen Progesterone Human placental lactogen Coisol Prolactin The main hormone responsible for insulin resistance is HPL. Ref:Dutta Obs 9e pg 55.', 'role': 'assistant'}]