This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Radiology
[{'content': 'Which of these factors has no effect on response of cells to irradiation? \nSelect and explain. \nA. Linear energy transfer, B. Oxygen, C. Image receptor used, D. Dose rate', 'role': 'user'}, {'content': "Answer: C \nExplanation: The dose required to produce a certain biologic effect is reduced as the linear energy transfer (LET) of the radiation is increased. Higher LET radiations (e.g., α particles) are more efficient in damaging biologic systems, because their high ionization density is more likely than X\xa0rays to induce double-strand breakage in DNA.\nThe greater cell damage sustained in the presence of oxygen is related to the increased amounts of hydrogen peroxide and hydroperoxyl free radicals formed.\nThe term 'dose rate' indicates the rate of exposure. Exposure of biologic systems to a given dose at a high dose rate causes more damage than exposure to the same total dose given at a lower dose rate.\nWhite and Pharoah's Oral\xa0 Radiology Principles and Interpretation 8th edition", 'role': 'assistant'}]