This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Medicine
[{'content': 'Antipsychotics are safer in the patient with \nSelect and explain. \nA. Infertility, B. Hypertension, C. Epilepsy, D. All of the above', 'role': 'user'}, {'content': 'Answer: B \nExplanation: (B) Hypertension # CVS:> Neuroleptics produce hypotension (primarily postural) by a central as well as peripheral action on sympathetic tone.> Chlorpromazine lowers seizure threshold and can precipitate fits in untreated epileptics.> The piperazine side chain compounds have a lower propensity for this action.# Endocrine:> They reduce gonadotropin secretion but amenorrhoea and infertility occur only occasionally.> ACTH release in response to stress is diminished -- corticosteroid levels fail to increase under such circumstances.> Release of GH is also reduced but this is not sufficient to cause growth retardation in children or to be beneficial in acromegaly.', 'role': 'assistant'}]