This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Medicine
[{'content': 'Parkinsonism treatment involves \nSelect and explain. \nA. Dopamine release, B. Balance of Ach & dopamine in striatum, C. Either, D. None', 'role': 'user'}, {'content': 'Answer: B \nExplanation: (B) Balance of Ach & dopamine in striatum # PARKINSONISM (Paralysis Agitans):> The normally high concentration of dopamine in the basal ganglia of the brain is reduced in Parkinsonism, and pharmaco- logical attempts to restore dopaminergic activity with levodopa and dopamine agonists have been successful in alleviating many of the clinical features of the disorder.> An alternative but complementary approach has been restore the normal balance of cholinergic and dopaminergic influences on the basal ganglia with antimuscarinic drugs.> Central anticholinergics act by reducing unbalanced cholinergic activity in striatum of parkinsonian patients.> These are the only drugs effective in drug induced parkinsonism.> Central anticholinergics can be used alone in mild cases and when levodopa is contraindicated. Can be used in combination with levodopa to decrease its dose.', 'role': 'assistant'}]