This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': "Which of the following is not true about medullary carcinoma of thyroid - \nSelect and explain. \nA. Origin is from `C' cells of thyroid, B. Component of MEN-1, C. Multicentric in origin, D. Amyloid deposition", 'role': 'user'}, {'content': 'Answer: B \nExplanation: Medullary thyroid carcinoma is associated with MEN 2 (2A & 2B), and not with MEN-1.\nWhen medullary thyroid carcinoma occurs as a part of MEN syndrome, it may be multicentric.', 'role': 'assistant'}]