This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: NEET 2019, Subject name: Biochemistry
[{'content': 'Defect in Menke disease: \nSelect and explain. \nA. Lysyl hydroxylase, B. Lysyl oxidase, C. Prolyl hydroxylase, D. Prolyl oxidase', 'role': 'user'}, {'content': 'Answer: B \nExplanation: MENKE DISEASE / kinky OR STEEL HAIR SYNDROME- deficiency of copper results in defective crosslinking of collagen and elastin by the copper-dependent enzyme lysyl oxidase. Defect in dietary absorption of copper Die with in 5 years of age Kinky hair and growth retardation. menke disease is X linked disease due to mutation in ATP 7 A gene. This gene is present on Xp 12-13.', 'role': 'assistant'}]