This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Neurodegenerative Diseases, Subject name: Pathology
[{'content': "Neurofibrillary tangles are seen in? \nSelect and explain. \nA. Alzheimer's disease, B. Lewy body disease, C. Neurosyphilis, D. Shy dragger syndrome", 'role': 'user'}, {'content': "Answer: A \nExplanation: ANSWER: (A) Alzheimer's diseaseREF: Harrison's Internal Medicine 17th ed> Chapter 365. DementiaAlzheimer's disease most often presents with subtle onset of memory loss followed by a slowly progressive dementia that has a course of several years. Pathologically, there is diffuse atrophy of the cerebral cortex with secondary enlargement of the ventricular system. Microscopically, there are neuritic plaques containing A amyloid, silver-staining neurofibrillary tangles (NFTs) in neuronal cytoplasm, and accumulation of A42 amyloid in arterial walls of cerebral blood vessels.NFT also seen in supra nuclear palsy", 'role': 'assistant'}]