This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Substance abuse, Subject name: Psychiatry
[{'content': 'Which of the following is used to maintain abstinence in alcohol dependence \nSelect and explain. \nA. Naltrexone, B. Clonidine, C. Disulfiram, D. Naloxone', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Naltrexone (oral opioid receptor antagonist) probably interferes with alcohol-induced reinforcement by blocking opioid receptors., helping in maintaining alcohol abstinence. Ref: Sho textbook of Psychiatry by Niraj Ahuja 7th editon, page 42. Disulfiram also helps in alcohol abstinence but through its unpleasant reactions to alcohol intake.', 'role': 'assistant'}]