This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'A condition which does not have granuloma? \nSelect and explain. \nA. Infarction, B. TB, C. Sarcoidosis, D. Leprosy', 'role': 'user'}, {'content': 'Answer: A \nExplanation: The dominant histological characteristic of infarction is ischaemic coagulative necrosis, except in the\xa0central nervous system where the feature is that of liquefactive necrosis.\nIt will not lead to granuloma\xa0formation.\nGranuloma: Focus on chronic inflammation consisting of a microscopic aggregation of macrophages transformed into epithelium-like cells surrounded by a collar of mononuclear leucocytes, principally lymphocytes & occasionally plasma cells.\nTypes:\nForeign body granuloma, eg. talc, suture\xa0Immature granuloma: insoluble particles especially microbes, eg. tubercle granuloma.\nGranulomatous inflammation:\nTB, leprosy, sarcoidosis, cat scratch disease, brucellosis, syphilis, LGV, berylliosis, some mycotic\xa0infections.\nChemical mediators of DHS (delayed hypersensitivity) are:-\nIL2, IL3, TNF á, â, IFN by TH1 helper cells\n(The chief mediator is IFN Remember: The most important inflammatory mediator = TNF á\xa0TH2 helper cells secrete IL 3, 4, 5, 6, 10, 13', 'role': 'assistant'}]