This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
[{'content': 'Pyrogens act on which site of brain ? \nSelect and explain. \nA. Basal ganglia, B. Limbic system, C. Thalamus, D. Hypothalamus', 'role': 'user'}, {'content': "Answer: D \nExplanation: Ans. is 'd' i.e., Hypothalamus PyrogenesPyrogenes are substances that cause fever.Pyrogens may be exogenous or endogenousExogenous - Bacterial toxinsEndogenous - IL-1, TNF-a, IL-6, Interferons, Ciliory's neurotropic factorThese pyrogenes increase the level of PGE, in the hypothalamus that elevates the thermoregulatory set point and causes fever.", 'role': 'assistant'}]