This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': 'A 12 year old boy presents with hemetemesis, malena and mild splenomegaly. There is no obvious jaundice or ascitis. The most likely diagnosis is – \nSelect and explain. \nA. EHPVO, B. NCPF, C. Cirrhosis, D. Malaria with DIC', 'role': 'user'}, {'content': "Answer: A \nExplanation: Information in question are:\n\n\nPatient is 12 years male\nHematemesis, melena and mild splenomegaly —k signs of portal hypertension\nNo Jaundice or Ascitis\n\n\nSo, the boy in question has portal hypertension.\nThree most common causes of portal hypertension are:\n\n\nExtrahepatic portal vein obstruction (EHPVO)\nNon-cirrhotic portal fibrosis (NCPF)\nCirrhosis.\n\n\nIn cirrhosis, jaundice & ascitis are prominent. So, this option is ruled out.\nNow we are left with EHPVO and NCPF. Both these causes non-cirrhotic portal hypertension, i.e. portal hypertension without signs of liver dysfunction.\nBoth these have similar clinical picture except for the age of presentation.\nEHPVO is usually' seen in young male children (1st and 2nd decade) while NCPF is a disease of adults (25-35 years).\nSo, best answer here is EHPVO.", 'role': 'assistant'}]