This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Forensic Medicine
[{'content': 'The earliest manifestations of Chronic lead poisoning include - \nSelect and explain. \nA. Colic and constipation, B. Encephalopathy, C. Punctate basophilia, D. Lower limb paralysis', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Facial pallor is the earliest and most consistent symptom. However, among the given options, punctate basophilia is the earliest manifestation.', 'role': 'assistant'}]