This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti Adrenergic System, Subject name: Pharmacology
[{'content': 'Which of the following is the most beta-1 selective antagonist? \nSelect and explain. \nA. Acebutolol, B. Atenolol, C. Metoprolol, D. Bisoprolol', 'role': 'user'}, {'content': "Answer: D \nExplanation: Ans: D (Bisoprolol) Ref: Goodman & Gill man's The Pharmacological Basis of Therapeutics. 2011, 12th Edition, McGraw-Hill, Burton LL P 328Explanation:Bisoprolol is highly selective beta-1 selective antagonist among the given drugsHowever nehivolol has higher beta-1 selective antagonist than bisoprololBeta-1 selective antagonist includeAcebutololAtenololBetaxololBisoprololCeliprololEsmololMetoprololNebivolol", 'role': 'assistant'}]