This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Enzymes, Subject name: Biochemistry
[{'content': 'Which of the following is a biomarker of alcoholic hepatitis? \nSelect and explain. \nA. ALP, B. AST, C. LDH, D. GGT', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans. D. GGTGGT is a microsomal enzyme and its measurement provides a sensitive index to asses liver abnormality. It is highly elevated in biliary obstruction and alcoholism.* Serum g-glutamyl transferase (GGT) is the sensitive indicator of alcohol use.* For chronic viral hepatitis and nonalcoholic fatty liver, AST:ALT ratio <1* For alcoholic liver disease, AST:ALT ratio >2:1* Lactate dehydrogenase isozyme-5(LDH-5) is also a major diagnostic test for liver diseases', 'role': 'assistant'}]