This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetic and genetic disorders, Subject name: Pediatrics
[{'content': 'Non-invasive prenatal screening (NIPS) is paicularly useful in the modern era of diagnosis in clinical genetics. Which of the following statements is not true regarding this test? \nSelect and explain. \nA. Useful in screening for aneuploidies, B. Evaluates maternal blood for abnormalities, C. HIgh positive predictive value, D. Positive test need confirmation by invasive testing', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Non-invasive prenatal screening (NIPS) has a high negative predictive value. NIPS: Useful in screening high-risk pregnancies for aneuploidies Done after 10 weeks of gestation Evaluates maternal blood for screening Positive tests need confirmation by invasive testing (like amniocentesis, Chorionic villous sampling) Ref: Ghai essential pediatrics 9th edition Pgno: 643', 'role': 'assistant'}]