This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General anatomy, Subject name: Anatomy
[{'content': 'False about quinidine in is \nSelect and explain. \nA. It increases effective refractory period, B. Used in hypeension, C. Causes paradoxical tachycardia, D. Cinchonism is seen', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Refer kDT 6/e p 511,512 Quinidine has following propeies; Class 1a and 3 antiarrhythmic propeies Increase the effective refractory period Anti vagal action causes tachycardia. This tachycardia is paradoxical, because quinidine is a cardiac depressant and does not expected to increase the hea rate some Alpha blocking propey is and its use can cause hypotension and is not used for antihypeensive agent. At higher doses, Cinchonism occurs, characterized by ringing in ear, veigo, headache and visual disturbances ,mental changes and delirium Antimalarial action is Poorer than quinine. ECG changes:increase PR and QT interval, and broadens QRS complex, and change the shape of T wave', 'role': 'assistant'}]