This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Erythmato-Squamous and Lichenoid Eruption, Subject name: Skin
[{'content': 'Histological finding of Lichen planus - \nSelect and explain. \nA. Acanthosis, B. Hyperkeratosis, C. Basal cell degeneration, D. All of the above', 'role': 'user'}, {'content': "Answer: D \nExplanation: Ans. is 'd' i.e.. All of the above Histopathology in Lichen planus The basic pathology in lichen planus is the damage to the basal cell layer of epidermis leading to hydropic degeneration of basal cells.Epidermal thickening especially of granular cell layer - Hypergranulosis.Hyperkeratosis (Thickening of stratum cornuem)Acanthosis (Thickening of Stratum) malpighi.Subepidermal - lichenoid band due to deposition of lymphocytes & histiocytes in upper dermis.Dropping of melanin pigment from damaged keratinocytes of epidermis into dermis -pigment incontinence,This melanin is engulfed by macrophages which results information of cvtoid bodies (civatte or colloid bodies).Mox Joseph Histological cleft - Separation of epidermis in small clefts.", 'role': 'assistant'}]