This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'The monoclonal antibody useful in the treatment of PNH is: \nSelect and explain. \nA. Rituximab, B. Eculizumab, C. Infliximab, D. Adalimumab', 'role': 'user'}, {'content': 'Answer: B \nExplanation: By blocking the complement cascade downstream of C5, eculizumab abolishes complement-dependent intravascular hemolysis in all PNH patients, and significantly improves their quality of life. Reference: Harrisons Principles of Internal Medicine, 18th Edition, Page 884', 'role': 'assistant'}]