This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.V.S., Subject name: Pediatrics
[{'content': 'A 6-month-old baby with severe pallor and hepatosplenomegaly. Similar history is present in a sibling. Investigation of choice: \nSelect and explain. \nA. Bone marrow biopsy, B. Hb electrophoresis, C. Hb estimation, D. Platelet count', 'role': 'user'}, {'content': "Answer: B \nExplanation: b. Hb electrophoresis(Ref: Nelson's 20/e p 2323-2325, Ghai 8/e p 334-335)Presence of pallor and hepatosplenomegaly at 6 months of age with a positive family history indicates towards thalassemia major, which can be diagnosed by Hb electrophoresis.", 'role': 'assistant'}]