This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Other topics and Adverse effects, Subject name: Pharmacology
[{'content': 'Ivermectin is a \nSelect and explain. \nA. Cysticide, B. Taenicide, C. Filaricide, D. Anti-amoebic', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ivermectin is the drug of choice for Strongyloides and Onchocerca volvulus. It is a filaricide (effective against W. bancrofti and malayi).Ivermectin, a semisynthetic macrocyclic lactone, a mixture of avermectin B1a and B1b. It is derived from the soil actinomycete Streptomyces avermitilisIvermectin is used only orally in humans. The drug is rapidly absorbed, reaching maximum plasma concentrations 4 hours after a 12mg dose. Ivermectin appears to paralyze nematodes and ahropods by intensifying g-aminobutyric acid (GABA)-mediated transmission of signals in peripheral nervesReference: Katzung Pharmacology; 13th edition; Chapter 53; Clinical Pharmacology of the Antihelminthic Drugs', 'role': 'assistant'}]