This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cofactor and prosthetic groups, Subject name: Biochemistry
[{'content': 'Non vitamin coenzyme is : \nSelect and explain. \nA. Niacin, B. Coenzyme A, C. Lipoic acid, D. SAM', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Lipoic acid is a coenzyme (required for Pyruvate Dehydrogenase and Alpha-Ketoglutarate Dehydrogenase) but it is not a Vitamin (Option 3). Niacin is Vitamin B3 work as coenzyme in its active form Nicotinamide adenine dinucleotide (NAD) for a number of dehydrogenase enzymes in metabolism (Option 1). Coenzyme A is a derivative of Vitamin B5 - Pantothenic acid and works in acyi group transfer reaction (Option 2). SAM - is S-Adenosyl Methionine, which is a methyl donor. It is neither a Coenzyme, nor a Vitamin (Option 4). Extra information: Another Non-vitamin coenzyme is Tetrahydrobiopterin derived from guanosine triphosphate. Vitamin K is the only fat soluble vitamin which acts as coenzyme', 'role': 'assistant'}]