This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Renal carcinoma, Subject name: Pathology
[{'content': 'Which of the following renal tumours is associated with tuberous sclerosis? \nSelect and explain. \nA. Angiomyolipoma, B. Renal papillary adenoma, C. Nephroblastoma, D. Oncocytoma', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Angiomyolipoma of kidney: Benign tumour consists of vessels, smooth muscle, and fat originating from perivascular epithelioid cells. Present in 25% to 50% of patients with tuberous sclerosis, a disease caused by loss-of-function mutations in the TSC1 or TSC2 tumor suppressor genes. Tuberous sclerosis is characterized by: lesions of the cerebral coex that produce epilepsy and intellectual disability, a variety of skin abnormalities (sebaceous adenomas, etc.), unusual benign tumors at other sites, such as the hea', 'role': 'assistant'}]