This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pharmacology, Subject name: Pharmacology
[{'content': 'True statement about phase 2 clinical trial is: \nSelect and explain. \nA. Large number of healthy volunteers are studied, B. Used to determine maximum tolerated dose, C. Used to determine efficacy, D. Used to determine toxicity', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Phase II Clinical trial This is conducted by physicians who are trained as clinical investigators and involve 100-500 patients. The primary aim is the establishment of therapeutic efficacy, dose range in a controlled setting. Tolerability and pharmacokinetics are studied as an extension of phase I. they are single-blinded studies Ref; KD Tripathi pharmacology 7 th edition (page no; 80)', 'role': 'assistant'}]