This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': 'True statement about Rheumatic fever in children –a) Polyarthritisb) Caused by c hemolytic streptococcic) Erythema marginatum is most common manifestationd) Most common valve involvement is Mitrale) Erythema marginatum is common in face \nSelect and explain. \nA. b, B. c, C. ac, D. ad', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Most commonly involved valve in case of Rheumatic carditis is the mitral valve and the most common valvular deformity produced is mitral regurgitation.\nIn patient with Rheumatic heart disease the mitral valve alone is involved in 65% to 70% cases, followed by Aortic valve in 25% cases.\nThe valvular deformity becomes manifested when Rheumatic fever becomes chronic.\nChronic Rheumatic heart disese is characterized by organization of the acute inflammation and subsequent fibrosis.\nIn particular, the valvular leaflets becomes thickened and retracted causing permanent deformity.\nThe cardinal anatomical changes which are produced to chronicity are leaflet thickening. commissuralfizsion and shortening and thickening and fusion of the tendinous cords.\nThese abnormalities lead to the most serious complication of Rheumatic fever i.e., Valvular stenosis and /or regurgitation.\nMost common manifestation of Rheumatic fever is arthritis.\nErythema marginatum spares the face.', 'role': 'assistant'}]