This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Pregnancy induced Hypeension, Subject name: Gynaecology & Obstetrics
[{'content': 'Which one of the following anti-hypeensive drugs is contraindicated in pregnancy? \nSelect and explain. \nA. Alpha methyldopa, B. Hydralazine, C. Nifedipine, D. Frusemide', 'role': 'user'}, {'content': "Answer: D \nExplanation: Diuretics in pregnancy- In a PIH patient, furosemide is C/I as an anti-hypeensive because in PIH the intravascular volume is low. Thats because the pathology is Vasospasm and hence there is intravascular 'Low vloume'. Giving a diuretic would fuher decrease the intravascular volume and hence reduce the placental perfusion. However, in a pregnant female with Hypeension of pregnancy complicated with CHF/Pulmonary edema, then diuretics can be used", 'role': 'assistant'}]