This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'A patient suffering from\xa0symmetrical and persistent painless swelling of lacrimal and salivary gland with no or less xerostomia, responds\xa0to steroid therapy. What could be the possible\xa0diagnosis for this patient? \nSelect and explain. \nA. Mikulicz disease, B. Primary Sjogren syndrome, C. Secondary Sjogren syndrome, D. All of the above', 'role': 'user'}, {'content': 'Answer: A \nExplanation: IgG4-related disease (Mikulicz disease ) often requires immediate, aggressive treatment with systemic corticosteroids to prevent significant organ damage and failure. Glucocorticoid-sparing agents, such as azathioprine, mycophenolate mofetil, and methotrexate, also can be used. Most patients show a rapid response to immunosuppressive therapy and have a favorable prognosis. For patients with recurrent disease, B-cell depletion with rituximab can be effective.\n\xa0 \xa0\xa0\nThe treatment of the patient with Sjögren syndrome is mostly supportive. The dry eyes are best managed by periodic use of artificial tears.\xa0Artificial salivas are available for the treatment of xerostomia; sugarless candy or gum can help to keep the mouth moist. Symptoms often can be relieved by the use of oral hygiene products that contain lactoperoxidase, lysozyme, and lactoferrin.\nRef:\xa0ORAL AND MAXILLOFACIAL PATHOLOGY, Neville, FOURTH EDITION\xa0 page no 434,437', 'role': 'assistant'}]