This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Which of the following enzymes require Vitamin C for their activity? \nSelect and explain. \nA. Procollagen proline hydroxylase, B. Procollagen amino peptidase, C. Procollagen carboxyl peptidase, D. Lysyl oxidase', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Vitamin C plays the role of a coenzyme in hydroxylation of proline and lysine while protocollagen is converted to collagen\xa0 (i.e.\xa0 post-translational modification). The hydroxylation reaction is catalysed by lysyl hydroxylase\xa0 (for\xa0 lysine)\xa0 and prolyl\xa0 hydroxylase (for\xa0 proline).', 'role': 'assistant'}]