This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anaesthesia, Subject name: Pharmacology
[{'content': "Which of the following drug undergoes Hoffman's elimination? \nSelect and explain. \nA. Atracurium, B. Pancuronium, C. Mivacurium, D. Vecuronium", 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. (A) Atracurium(Ref: KDT 8th/e p380)Atracurium and cis-atracurium undergo Hoffmann's elimination (spontaneous non-enzymatic molecular rearrangement) and are the agents of choice for patients with hepatic or renal insufficiency.Atracurium is metabolized to laudanosine that is responsible for seizures. Cis-atracurium is relatively safe in this regard.", 'role': 'assistant'}]