This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
[{'content': 'In chronic Hepatitis B infection, which one of the following markers is indicative of active viral replication and the corresponding risk of disease transmission ? \nSelect and explain. \nA. HBe antigen, B. HBs antigen, C. Anti - HBe, D. Anti - HBs', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., HBe antigen", 'role': 'assistant'}]