This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Virology, Subject name: Microbiology
[{'content': 'Active replication in Hepatitis B in fection is indicated by - \nSelect and explain. \nA. HBeAg, B. HBsAg, C. HBcAg, D. Anti-HBsAg', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Circulating HBeAg Indicate of active intrahepatic replication REF:MICROBIOLOGY ANANTHA NARAYANAN NINTH EDITION PAGE.547', 'role': 'assistant'}]