This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti-Helminths, Subject name: Pharmacology
[{'content': 'Scabies oral treatment of choice: \nSelect and explain. \nA. Permethrin, B. Benzyl Benzoate, C. Ivermectin, D. Lindane', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans. (c) IvermectinRef. KDT 6th ed. 864* Scabies is caused by an ectoparasite sarcoptes scabei. It is highly contagious. The mite burrows through the epidermis, laying eggs which form papules that itch intensely.* Most common site of entry- finger webs.* Drugs used are:# Permethrin: broad spectrum and potent insecticide, currently most efficacious. It is DOC for scabies. MOA: It causes neurological paralysis in insects by delaying depolarization. Single application needed in most cases. Very less toxicity; 100% cure rate.# Lindane: another broad spectrum insecticide. Efficacy lower than permethrin. MOA: kills lice and mites by penetrating through their chitinous cover and affecting the nervous system.# Benzyl benzoate: oily liquid with a faint aromatic smell. It is applied over face and neck after a bath. A second coat is applied next day which is washed after 24 hours.# Crotamiton# Sulfur# Ivermectin: highly effective in scabies and pediculosis as well. It is the only ORALLY administered drug which is used for scabies (ectoparasitosis) A single dose of 0.2 mg/kg has cured almost 90- 100% of population. It is contraindicated in children < 5 yrs, pregnant and lactating women.', 'role': 'assistant'}]