This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: CLL & CML, Subject name: Medicine
[{'content': 'Richter transformation is conversion of? \nSelect and explain. \nA. CLL into DLBCL, B. DLBCL into CLL, C. SLL into CLL, D. CLL into SLL', 'role': 'user'}, {'content': "Answer: A \nExplanation: MC B cell NHL : DLBCL CLL/SLL (Small lymphocytic lymphoma) | Richter transformation DLBCL (Diffuse lager B cell Lymphoma) Clinical signs of Richter's transformation include rapid progression in lymphadenopathy and constitutional symptoms including fatigue, night sweats, fever, and weight loss. LDH is usually high. Therapy for DLBCL Richter's transformation usually involves combination chemoimmunotherapy.", 'role': 'assistant'}]