This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Autonomic nervous system, Subject name: Pharmacology
[{'content': 'Cholinesterase activators are useful for treatment of which poisoning ? \nSelect and explain. \nA. Paraquat, B. Parathion, C. Carbamates, D. Organochlorocompounds', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ref:KD Tripathi pharmacology 6th edition (page.no: 99,105) Cholinesterase reactivators like Oximes(pralidoxime) are used to restore neuromuscular transmission in case of organophosphate anti-ChE poisoning. Organophosphates are Dyflos (DFP) Echothiophate Parathion, Malathion Diazinon(TIK-20) Tabun, Sarin, Soman. Pralidoxime attaches to anionic site of enzyme which remains unoccupied in presence of OP inhibitors. It's Oxime end react with phosphorus atom attached to the esteratic site. Oxime-Phosphonate so formed diffuses away leaving the reactivated ChE.", 'role': 'assistant'}]