This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Screening, Subject name: Social & Preventive Medicine
[{'content': 'ELISA is performed on a population with low prevalence, What would be the result of performing double screening ELISA tests- \nSelect and explain. \nA. Increased sensitivity and positive predictive value, B. Increased sensitivity and negative predictive value, C. Increased specificity and positive predictive value, D. Increased specificity and negative predictive value', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ref: Parks 23rd edition pg 139 Double ELISA meaning screening test is done in series. Series screening test : Sensitivity decreases Specificity increases PPV increases NPV decreases', 'role': 'assistant'}]