This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Drug with beta adrenergic blocking, with antioxidant, with calcium channel blocking, with alpha 1 antagonist activity is ? \nSelect and explain. \nA. Esmolol, B. Carvedilol, C. Nebivolol, D. Levobunolol', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., Carvedilol Carvedilol Carvedilol is a b1 + b2 + a1 adrenoceptor blocker with a : b blocking propey of 1 : 9. It has antioxidant and antimitotic propey. It produces peripheral vasodilation due to a-1 blockade as well as calcium channel blockade (direct effect). It is used in hypeension and angina. It is used as cardioprotective in CHF. t1/2 is 2-8 hrs. It is eliminated through liver and kidney. It causes ohostatic hypotension.", 'role': 'assistant'}]