This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Carbohydrates, Subject name: Biochemistry
[{'content': 'Which of the following carbohydrate metabolism is used for liver function assessment? \nSelect and explain. \nA. Galactose intolerance test, B. Sucrose intolerance test, C. Glucose intolerance test, D. Lactose intolerance test', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans: a (Galactose intolerance test) Ref: Vasudevan 4th ed/p.484Galactose is almost exclusively metabolised by liver.The rate limiting step is initial conversion of galactose to galactose-1 -phosphate.The rate of utilisation of galactose is directly proportional to functional liver mass.Reactions and its rate limiting enzymes:-1) Glycolysis - Phosphofructokinase2) Glycogen synthesis - Glycogen synthetase3) Glycogenolysis - Glycogen phosphorylase4) TCA cycle - Isocitrate dehydrogenase5) Fatty acid synthesis - Acetyl CoA carboxylase6) Cholesterol synthesis - HMG CoA reductase7) Ketone body synthesis - HMG CoA synthetase8) Bile acid synthesis - 7-'?-hydroxylase9) Catecholamine synthesis - Tyrosine hydroxylase10) Urea synthesis - Carbamoyl transferase", 'role': 'assistant'}]