This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': 'The protective effects off breast milk are known to be associated with – \nSelect and explain. \nA. IgM antibodies, B. Lysozyme, C. Mast cells, D. IgA antibodies', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Although antibodies and Lysozyme, both are important for the protective effects of breast milk, antibodies play a major role. Out of IgM and IgA antibodies, breast milk is especially rich in secretory IgA which is the single best answer here.\nProtective role of breastfeeding against infection \n\nBreast milk provides protection against infection because of the following facts -\n\n1. The breast milk is clean and uncontaminated\n2. Breast milk contains several antiinfective factors -\n\nAntibodies → secretory IgA, IgM\nLysozyme\nAntistaphylococcal factor\nSpecific inhibitory substances against viral infections.\nLactoferrin → Inhibits growth of E. coli.\nBile stimulated lipase → kills Entamoeba histolytica and Giardia lamblia.\nBifidus factor → Inhibits growth of E. coli\nPara-amino-benzoic acid (PABA) → Provides protection against malaria\nPhagocytic macrophages and lymphoid cells\n\n3. Lower pH of the stool of breastfed infants contributes to the favourable intestinal flora more bifidobacteria and lactobacilli, fewer E. coli.', 'role': 'assistant'}]