This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Anaesthesia
[{'content': 'Malignant hypehermia is caused due to which of the following mechanism? \nSelect and explain. \nA. Increased intracellular NA, B. Decreased intracellular chlorine, C. Increased intracellular Ca, D. Increased serum K', 'role': 'user'}, {'content': "Answer: C \nExplanation: The mechanism involves a sudden rise in intracellular calcium due to release of stored calcium in sarcoplasmic reticulum, stimulating contraction, rhabdomyolysis and a hypermetabolic state.(Refer: stoelting's pharmacology and physiology in anaesthetic practice, 5th edition, pg no.823)", 'role': 'assistant'}]