This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Zollinger Ellision Syndrome, Subject name: Medicine
[{'content': 'Refractory gastric ulcer is defined as. \nSelect and explain. \nA. Ulcer that fails to heal despite 4 weeks of regular proper dose PPI, B. Ulcer that fails to heal despite 8 weeks of regular proper dose PPI, C. Ulcer that fails to heal despite 12 weeks of regular proper dose PPI, D. Ulcer that fails to heal despite 16 weeks of regular proper dose PPI', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Refractory gastric ulcer - Fails to heal by 3 month of regular proper dose PPI (Reason could be - Zollinger Ellison syndrome) Refractory Duodenal Ulcer : > 8 weeks with regular PPI Treatment Refractory Gastric Ulcer : > 12 weeks', 'role': 'assistant'}]