This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: CNS Tumors, Subject name: Pathology
[{'content': 'A patient has multiple meningiomas, bilateral vestibular schwannomas and early onset cataract. The most likely diagnosis is: - \nSelect and explain. \nA. Neurofibromatosis type 2, B. Tuberous sclerosis, C. Von Hippel Lindau (VHL) disease, D. Sturge-Weber syndrome', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Neurofibromatosis Type 2 Autosomal dominant disorder resulting in a range of tumors, most commonly bilateral eighth nerve schwannomas, multiple meningiomas, and ependymomas of the spinal cord. In addition, a characteristic type of cataract, juvenile posterior subcapsular lenticular opacity, occurs in NF2. This syndrome is caused by mutation of the NF2 gene on chromosome 22q; NF2 encodes a protein called neurofibromin 2/merlin protein.', 'role': 'assistant'}]