This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy, Subject name: Pharmacology
[{'content': 'Mechanism of action of Triazoles \nSelect and explain. \nA. Inhibits cell wall synthesis, B. Inhibits ergosterol biosynthesis, C. Inhibits glucan synthesis, D. Inhibits tubulin', 'role': 'user'}, {'content': 'Answer: B \nExplanation: * Triazole antifungals (Fluconazole, Itraconazole, Voriconazole, Posaconazole) inhibit 14-sterol demethylase --> impair the biosynthesis of ergosterol--> resulting in depletion of membrane ergosterol along with accumulation of the toxic product 14-methyl-3,6- diol --> leading to fungal growth arrest. Ref:- Goodman & Gilman Pharmacological Basis of Therapeutics 13th Ed; Pg num:- 1091', 'role': 'assistant'}]