This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': "In Wegener's glomerulonephritis, the characteristic features seen is: \nSelect and explain. \nA. Focal necrotizing glomerulonephritis, B. Granulomas in the vessels wall, C. Interstitial granulomas, D. Nodular glomerulosclerosis", 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans:B.)Granulomas in the vessels wall Granulomatosis with polyangiitis (GPA), formerly known as Wegener granulomatosis, is a rare multisystem autoimmune disease of unknown etiology. Its hallmark features include necrotizing granulomatous inflammation and pauci-immune vasculitis in small- and medium-sized blood vessels. Cytoplasmic antineutrophil cytoplasmic antibody (c-ANCA) directed against PR3 is most specific for GPA.', 'role': 'assistant'}]