This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Ophthalmology
[{'content': 'Calcification in retinoblastoma is due to \nSelect and explain. \nA. Necrosis, B. Hemorrhage, C. Scleral rupture, D. RPE metaplasia', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Calcification in retinoblastoma is due to retinal pigment epithelium metaplasia.', 'role': 'assistant'}]