This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cailage tissue & cell junctions, Subject name: Anatomy
[{'content': 'Which one of the following makes epiphyseal cailage matrix fail to calcify? \nSelect and explain. \nA. Thyroxine, B. Hypervitaminosis A, C. Hypovitaminosis D, D. Hydrocoisone', 'role': 'user'}, {'content': 'Answer: C \nExplanation: In the absence of vitamin D, epiphyseal chondrocytes continue to proliferate, but their matrix does not calcify, which leads to rickets.', 'role': 'assistant'}]