This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of Purines and Pyrimidines, Subject name: Biochemistry
[{'content': 'Purine metabolism produces - \nSelect and explain. \nA. b-alanine, B. NH3, C. CO2, D. Uric acid', 'role': 'user'}, {'content': "Answer: D \nExplanation: Ans. is 'd' i.e., Uric acid o Humans catabolize purines (adenine and guanine) to uric acid.o Humans catabolize purines to uric acid.o But, first purines are catabolized to xanthine, which is further catabolized to purine.o In mammals other than higher primates (in non primate mammals), uric acid is converted to water soluble abandon by enzyme 'uncase'. However, human lack uricase, therefore the end product of purine catablism is uric acid, which is excreted.", 'role': 'assistant'}]