This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Ophthalmology
[{'content': 'Retinoblastoma – \nSelect and explain. \nA. Is inherited in 50% of cases, B. Is caused by deletion of 11q14, C. Rosettes suggest good prognosis, D. Causes death in 60% of sufferers in the UK', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Rosettes are feature of well differentiated retinoblastoma, therefore suggest the good prognosis.\nHereditary retinoblastoma accounts for 40% of cases and the gene is located at 13q14 chromosome.\nPrognosis is fair with 70-85% survival rate if the eyeball is enucleated before the occurrence of extra ocular extension.', 'role': 'assistant'}]