This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'Anti mitochondrial Ab seen typically in: \nSelect and explain. \nA. Primary Biliary cirrhosis, B. Hepatitis B, C. Hepatitis C, D. Hepatitis A', 'role': 'user'}, {'content': "Answer: A \nExplanation: Primary Biliary cirrhosis is a disease characterized by chronic inflammation and fibrous obliteration of intrahepatic bile duclioles due to an unknown (primary) stimulus.\n\xa0\nEtiology\nPBC is believed to due to an autoimmune etiology as it is often associated with other auto immune disorders such as\xa0\nCRCST syndrome: Calcinosis, Raynaud's phenomena, Esophageal dysmotility, Sclero-dactily. Telangiectasia\n\xa0\nSicca syndrome\nAutoimmune thyroiditis\nRenal tubular acidosis\nAnti mitochondrial antibody (IgG is positive)\n\xa0\nClinical feature\nMost patients arc asymptomatic.\nPruritis is commonest/earliest symptom\nJaundice\nDeficiency of fat soluble vitamin due to malabsorption leads to:\nVit D deficiency → Bone pain—Osteomyelitis Vit K deficiency →\xa0bleeding bruising\nVit A deficiency~»Night Blindness IXanthelisma and Xanthomas arc due to elevation of serum lipids.Lab finding\nIncreased Serum alkaline phosphates.Positive mitochondrial antibody sensitive and specific.", 'role': 'assistant'}]