This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Lipids, Subject name: Biochemistry
[{'content': 'Ketone body is not utilised by - \nSelect and explain. \nA. Neurons, B. Kidney, C. Muscle, D. Liver', 'role': 'user'}, {'content': "Answer: D \nExplanation: Ans. is 'd' i.e., Liver* Ketone bodies are synthesised in conditions of starvation and diabetes mellitus* They are synthesised by incomplete oxidation of fatty acids as oxaloacetate is unavailable* They get synthesised in liver* Rate limiting enzyme of ketone body synthesis is HMG CoA lyase* Ketone bodies get utilised in extrahepatic tissues including neurons (Ketone bodies can cross Blood brain barrier as they are polar), muscle cells and kidney* Ketone bodies can not be utilised in liver. Because liver lacks the enzyme Thiophorase or Succinyl CoA Acetoacetate CoA transferase.", 'role': 'assistant'}]