This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Ophthalmology
[{'content': 'In case of anisocoria when 1% pilocarpine is instilled into the eye with abnormally dilated pupil, pupil remains dilated. Cause of anisocoria may be- \nSelect and explain. \nA. Adies pupil, B. Pharmacological blockage, C. Uncal herniation, D. Diabetic III cranial nerve palsy', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Anisocoria refers to difference between the size of two pupils. In the question, anisocoria is due to abnormally dilated pupil (Has been mentioned in question).\nPilocarpine is installed into the eye with dilated pupil and there is no constriction. (pupil remains dilated).\nPilocarpine is a direct muscarinic agonist and cause pupillary constriction.\nResponse to pilocarpine is as follows:\n\nPupil will constrict with 1% pilocarpine in 3rd nerve palsy, anxiety state pupil, sympathomimetic drug use.\nAdies pupil constricts even with low dose (0.125%) as there is denerration hypersensitivity in Adies pupil.\nA pharmacological dilated pupil will not constrict after pilocarpile instillation. Other conditions where dilated pupil will not constrict are fixed pupil (iritis), and traumatic mydriasis.\n\nMydriatic drug effect (Pharmacological block).\nFixed pupil (iritis).\nTraumatic mydriasis.\n3rd Cranial nerve palsy.\nAnxiety state pupil.\nSympathomimetic drug induced dilatation.', 'role': 'assistant'}]