This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'What is the histological appearance of brain in CJD? \nSelect and explain. \nA. Neuronophagia, B. Micro abscess, C. Demyelination, D. Spongiform changes', 'role': 'user'}, {'content': 'Answer: D \nExplanation: CID(Creutfeldt Jakeb Disease) is a prion disease characterised by spongiform changes in the brain.', 'role': 'assistant'}]