This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: JIPMER 2018, Subject name: Pathology
[{'content': 'Myeloma associated with good prognosis: \nSelect and explain. \nA. t(11:14), B. deletion of 13q, C. del 17p, D. t(14,16)', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Multiple Myeloma:- Plasma cell tumor that manifest with multiple lytic bone lesion associated with pathologic fractures and hypercalcemia. Neoplastic plasma cell suppress normal humoral immunity and secrete paial Ig that are nephrotoxic Associated with diverse Translocation involving the Ig H locus, frequent dysregulation and overexpression of D cyclin. Translocation t (11:14 ):- Good prognosis.', 'role': 'assistant'}]