This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Conversion of glucose to glucose-6 phosphate in human liver is by \nSelect and explain. \nA. Hexokinase only, B. Glucokinase only, C. Hexokinase and glucokinase, D. Glucose-6-phosphate dehydrogenase', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Hexokinase and glucokinase may be considered as iso-enzymes. Glucokinase is under the influence of insulin; but hexokinase is not. Hexokinase is present in most tissues. Glucokinase with a high Km for glucose is present in liver and beta cells. Glucokinase is induced by insulin.\nReference: Vasudevan 7th\xa0 ed, pg 109', 'role': 'assistant'}]