This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': "A child is diagnosed of having Gaucher's disease. Histology may show accumulation of the following substance: \nSelect and explain. \nA. Glucocerebroside, B. Galactolipid, C. Both of the above, D. None of the above", 'role': 'user'}, {'content': 'Answer: A \nExplanation: Gaucher disease is the most common autosomal recessive lipid storage disorder. Deficiency of the enzyme beta glucocerebrosidase results in accumulation of the glycolipid glucocerebroside in the cells of the macrophage-monocyte system. Diagnosis of Gaucher disease depends on demonstration of deficiency of beta glucocerebrosidase or identification of mutations in the beta glucocerebrosidase gene. Ref: Zimran A., Elstein D. (2010). Chapter 73. Lipid Storage Diseases. In J.T. Prchal, K. Kaushansky, M.A. Lichtman, T.J. Kipps, U. Seligsohn (Eds), Williams Hematology, 8e.', 'role': 'assistant'}]