This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': "Characteristic pathological feature of Parkinson's disease is presence of - \nSelect and explain. \nA. Lewy bodies, B. Babes nodule, C. Neuro fibrillary tangle, D. Negri-bodies", 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Lewy Bodies Pathologic Examiniation in Parkinsons shows : Gross / Macroscopically : Pallor of the substantia nigra and locus ceruleus o Microscopic Examination : 1. Loss of catecholaminergic neurons in these regions + gliosis 2. Lewy bodies. o Lewy Bodies :are inclusion bodies found within neurons in Parkinsons disease. o Lewy bodies are single or multiple, intra-cytoplasmic, cosinophilic, round and elongated inclusions that often have a dense core surrounded by a pale halo. Ultrastructurally :These are composed of fine filaments, densely packed in the core but loose at the rim.", 'role': 'assistant'}]