This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'AML with worst prognosis is : \nSelect and explain. \nA. 8/21 translocation, B. Inversion 16, C. Normal Cytogenetics, D. Monosomy 7', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Answer is D (Monosomy 7) Patient with a complex karyotype, inv (3), or -7 (monosomy) have a poor prognosis. - Harrison', 'role': 'assistant'}]