This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Medicine
[{'content': 'Which of the following of drugs is not recommended in septic shock \nSelect and explain. \nA. Normal saline, B. Activated protein C, C. Steroids, D. Rituximab', 'role': 'user'}, {'content': "Answer: D \nExplanation: Initial management of hypotension is the administration of iv fluids - normal salineAdrenal insufficiency is strongly suspected in septic patients with refractory hypotension and hydrocoisone may be given Recombinant activated protein C (aPC) was the 1st drug to be approved by FDA for the treatment of patients with severe sepsis or septic shock(ref: Harrison's 18/e p 2223, 17/e p1699-1701)", 'role': 'assistant'}]