This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
[{'content': "All are congential myopathies exceptaEUR' \nSelect and explain. \nA. Central Core myopathy, B. Centronuclearmyopathy, C. Z band myopathy, D. Nemalin myopathy", 'role': 'user'}, {'content': 'Answer: C \nExplanation: Z band Myopathes Congenital Myopathies are characterized by Onset at bih or in early infancy with muscle Weakness and decreased muscle tone Very slowly progressive or non progressive course & long survival Specific histologic changes on muscle biopsy Congenital Myopathies Disease . Central core disease . Nemaline Myopathy . Centro Nuclear Myopathy Histological Characteristics Amorphous central core in myofibrils with absence of oxidative enzymes Elongated crystalline rods composed of Tropomyosin present beneath sarcolemma : shows periodicity on electron microscopy. Nuclei occupy the central pa of the myofibril. P Secondary Congenital Myopathy associated with Glycogen storage disease Glycolytic enzyme Deficiency Ceain disorders of lipid Metabolism e.g. Carnitine Deficiency Acquired Myopathy Endocrine - Thyrotoxicosis - Cushing disease - Acromegaly Familial periodic paralysis - Potassium deficiency or excess Malignant neoplasm - Paraneoplastic syndromes', 'role': 'assistant'}]