This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Pathology
[{'content': 'Adult polycystic kidney disease is \nSelect and explain. \nA. Autosomal recessive, B. Autosomal dominant, C. X-linked recessive, D. X-linked dominant', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ref: Robbins Pathology, 9th ed. pg. 946* ADPKD is autosomal dominant--Polycystic kidney disease.* Occurs due to mutation in PKD 1 and PKD 2 gene* MC type of mutation: PKD 1. (80-85%)* Pathological feature: Large multicystic kidney. It also involves commonly:# MC: Liver-Polycystic liver disease (40%)# Heart: Mitral valve prolapse (20-25%)# Brain: Berry aneurysm', 'role': 'assistant'}]