This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Tadpole cells/comma shaped cells on histopathology are seen in - \nSelect and explain. \nA. Trichoepithelioma, B. Spideroma, C. Rhabdomyosarcoma, D. Histiocytoma', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Histology of rhabdomyosarcoma \n\nThe diagnostic cell of rhabdomyosarcoma is rhabdomyoblast.\nRhabdomyoblast contains eccentric eosinophilic granular cytoplasm rich in thick and thin filaments.\nThe rhabdomyoblasts may be -\n\n\nRound\nElongated → Tadpole or Strap cells.\n\n\nIt has three variants\n\n\nEmbryonal\nAlveolar\nPleomorphic\n\n\nRhabdomyoblasts are positive for desmin, MYOD1 and Myogenin.', 'role': 'assistant'}]