This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolic Disorders Leading to Osteosclerosis, Subject name: Orthopaedics
[{'content': 'Which of the below is a feature of Osteogenesis imperfecta? \nSelect and explain. \nA. Blue sclera, B. Cataract, C. Anterior uveitis, D. Retinal detachment', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Blue sclera o Osteogenesis imperfecta, also known as brittle bone disease, is due to defective collagen type 1 synthesis.o It is inherited mostly as autosomal dominant but autosomal recessive pattern also seen in severe form. Clinical features of osteogenesis imperfecta# Blue sclera# Dentinogenesis imperfecta a Generalized osteoporosis# Osteoporosis given rise to bowing and multiple fractures. Fracture are usually due to trivial trauma but surprisingly heal well.# Other features: Deafness due to otosclerosis, joint laxity, dwarfism, broad skull, poorly calcified decidual teeth (Permanent teeth are normal).# Radiology shows wormian bones in the skull.", 'role': 'assistant'}]