This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Maintainance dose of drug is dependent on ? \nSelect and explain. \nA. Half life, B. Volume of distribution, C. Total body concentration, D. Loading dose', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Half life Loading dose is governed by volume of distribution. Maintenance dose is governed by clearance or P/2. The drug with sho t1/2 with loading and maintenance dose concept - Lignocaine.", 'role': 'assistant'}]