This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Resistance to drugs in Tuberculosis develops by - \nSelect and explain. \nA. Transduction, B. Conjugution, C. Transformation, D. Mutation', 'role': 'user'}, {'content': "Answer: D \nExplanation: Ans. is 'd' i.e., Mutation o The most common mechanism of antitubercular drugs resistance is by mutation - INH --> Catalase - peroxidase gene (Kat G) or inh A gene. Rifampin --> rpo B gene PZA --> pnc A gene ETB --> emb B gene Streptomycin --> 16 S rRNA gene (rrs) or ribosomal protein S-12 gene (rpst).", 'role': 'assistant'}]