This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Integrated QBank, Subject name: Unknown
[{'content': 'A 4-year-old child presented with symptoms of unsteady gait, tremors and frequent shivering in the body along with headaches and dizziness for past 6 months. There was history of frequent chest infections and few episodes of seizures in the past. The child was normal at bih. O/E: - Speech, hearing and visual impairment Discoloration of areas of skin exposed to sunlight. MRI brain was done along with MR spectroscopy which showed a choline peak. The gene responsible for the above condition is present on which of the following chromosome: - \nSelect and explain. \nA. 11q, B. 11p, C. 12q, D. 12p', 'role': 'user'}, {'content': 'Answer: A \nExplanation: This is a classical case of ataxia telangiectasia. First image shows ocular telangiectasias. 2ndimage shows MRI demonstrating cerebellar volume loss and compensatory enlargement of the 4thventricle. Ataxia-telangiectasia: - Complex syndrome with immunologic, neurologic, endocrinologic, hepatic, and cutaneous abnormalities. 11q23 gene defect Presents with Progressive cerebellar ataxia Sinopulmonary disease Variable humoral and cellular immunodeficiency', 'role': 'assistant'}]