This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Other topics and Adverse effects, Subject name: Anatomy
[{'content': 'All of the following statements about amlodipine are true except: \nSelect and explain. \nA. It acts by conversion to an active metabolite in the liver, B. It has a very large volume of distribution, C. It undergoes very little first pass metabolism and possesses high and consistent oral bioavailability, D. It has a very long elimination half life', 'role': 'user'}, {'content': 'Answer: A \nExplanation: (Ref: KDT 6/e p531) Amlodipine is the longest acting DHP. It undergoes little first pass metabolism and is distributed widely. metabolites of amlodipine are inactive.', 'role': 'assistant'}]