This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Regarding oncogenesis, all are true except: \nSelect and explain. \nA. Proto-oncogenes are activated by chromosomal translocation, B. Malignant transformations involves accumulation of mutations in proto-oncogenes and tumor suppressor genes, C. Point mutation of somatic cells, D. Increase in telomerase activity causes anti-tumor effects', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Activation of proto-oncogene results in cancer causing oncogenes by following mechanisms:', 'role': 'assistant'}]