This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
[{'content': 'Which of the following cells do not act as antigen presenting cells. ?- \nSelect and explain. \nA. T-cells, B. B-cells, C. Macrophages, D. Osteoclasts', 'role': 'user'}, {'content': "Answer: A \nExplanation: Answer is option 1 T cell responses differ from B cell responses in at least two crucial ways. First, T cells are activated by foreign antigen to proliferate and differentiate into effector cells only when the antigen is displayed on the surface of antigen-presenting cells in peripheral lymphoid organs. The T cells respond in this manner because the form of antigen they recognize is different from that recognized by B cells. Whereas B cells recognize intact antigen, T cells recognize fragments of protein antigens that have been paly degraded inside the antigen-presenting cell. The peptide fragments are then carried to the surface of the presenting cell on special molecules called MHC proteins, which present the fragments to T cells. T cells don't act as antigen presenting cells.", 'role': 'assistant'}]