This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Acyanotic congenital hea diseases, Subject name: Pediatrics
[{'content': 'Holt-Oram syndrome is characterized by? \nSelect and explain. \nA. ASD, B. VSD, C. TGA, D. TAPVC', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Holt-Oram syndrome: - Autosomal dominant disorder - Characterized by - skeletal abnormalities of hands and arms like: Hypoplastic/ absent thumbs, radii Triphalangism Phocomelia - Cardiac anomalies ASD 1st degree hea block TRIPHALANGISM phacomelia', 'role': 'assistant'}]