This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'A variety of basic assays are used to detect autoantibodies. Nephelometry is based on the principle of: \nSelect and explain. \nA. Light attenuated in intensity by scattering, B. Refraction of light, C. Reduced transmission of light, D. Filtration of solutes by kidney', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Nephelometry measures the interaction of antibodies and antigens in solution, detecting immune complex formation by monitoring changes in the scattering of an incident light. Ref: Imboden J.B. (2007). Chapter 3. Laboratory Diagnosis. In J.B. Imboden, D.B. Hellmann, J.H. Stone (Eds), CURRENT Rheumatology Diagnosis & Treatment, 2e.', 'role': 'assistant'}]