This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'Which of the following hepatitis viruses have significant perinatal transmission? \nSelect and explain. \nA. Hepatitis A virus, B. Hepatitis B virus, C. Hepatitis C virus, D. Hepatitis E virus', 'role': 'user'}, {'content': 'Answer: B \nExplanation: The hepatitis virus with significant perinatal transmission is Hepatitis - B virus. Hepatitis - C virus may also be transmitted if there are high levels of viremia. Hepatitis B is a DNA virus, it is acquired perinatally from a carrier mother, or later in life from exposure to contaminated blood through shared needles, needle sticks, skin piercing, tattoos or sexual transmission. Infants are infected with hepatitis B at the time of bih. Intrauterine transmission of this virus occur rarely. Ref: Harrisons Internal Medicine, 18th Edition, Chapter 304 ; CURRENT Diagnosis and Treatment: Pediatrics, 20th Edition, Chapter 1', 'role': 'assistant'}]