This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Blood, Subject name: Pediatrics
[{'content': 'Red cell Protoporphyrin levels more than 100 microgram/ dL is suggestive of which of the following? \nSelect and explain. \nA. Iron deficiency anemia, B. Lead poisoning, C. Myelodysplasia, D. All', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. a (Iron deficiency anemia) (Ref. Harrison 18th/ ch. 103)RED CELL PROTOPORPHYRIN LEVELS# Protoporphyrin is an intermediate in the pathway to heme synthesis.# Under conditions in which heme synthesis is impaired, protoporphyrin accumulates within the red cell.# This can reflect an inadequate iron supply to erythroid precursors to support hemoglobin synthesis.# Normal values are less than 30 microg/dL of red cells.# In iron deficiency, values in excess of 100 microg/dL are seen.# The most common causes of increased red cell protoporphyrin levels are absolute or relative iron deficiency and lead poisoning.', 'role': 'assistant'}]