This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Which of the following drug inhibits the enzyme of initial step of cholesterol synthesis ? \nSelect and explain. \nA. Lovastatin, B. Gemfiberozil, C. Probucol, D. Cholestyramine', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Lovastatin o Statins (Lovastatin) competitively inhibit the conversion of HMG-CoA to mevalonate (rate limiting step in cholesterol synthesis) by inhibiting the enzyme HMG-CoA reductase.", 'role': 'assistant'}]