This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti-Fungal Drugs, Subject name: Pharmacology
[{'content': 'Regarding newer formulations of amphotericin B, which of the following statements is accurate? \nSelect and explain. \nA. Amphotericin B colloidal dispersion cause less infusion related reactions than conventional amphotericin B., B. They are more effective in fungal infections than conventional preparations because they increase tissue uptake of amphotericin B, C. They have decreased systemic toxicity, D. They have wider spectrum of antifungal activity than conventional formulations of amphotericin B', 'role': 'user'}, {'content': 'Answer: C \nExplanation: NEWER FORMULATIONS OF AM-B : (Has Decreased systemic toxicity) AMPHOTERICIN B COLLOID DISPERSION (ABCD) - MAX INFUSION RELATED REACTION AMPHOTERICIN B LIPID COMPLEX (ABLC) LIPOSOMAL AMPHOTERICIN B (USED FOR T/T OF KALA AZAR) -MINIMUMINFUSION RELATED REACTION * Lesser uptake in the tissues like kidney * More expensive * Similar in efficacy and antifungal spectrum as conventional preparations AMPHOTERICIN B (CONVENTIONAL) Usually given in slow iv infusion Very well distributed all over the body and poorly distributed in CN', 'role': 'assistant'}]