This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'How does hyperammonemia inhibit TCA cycle \nSelect and explain. \nA. By depleting Alpha Ketoglutarate, B. By depleting Oxaloautate, C. By increasing concentration of alpha ketoglutarate, D. By increasing concentration of oxaloautate.', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Build up of cummonemia which occurs in area cycle disorders or advanced liver disease inhibits TCA cycle by depleting Alpha ketoglutarate.', 'role': 'assistant'}]