This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemistry of Carbohydrates, Amino sugars, and Mucopolysaccharides, Subject name: Biochemistry
[{'content': 'A child suffered from a viral illness for which he took aspirin. 3 days later the child presented to the emergency with altered sensorium and icterus. What is the underlying biochemical defect - \nSelect and explain. \nA. Beta oxidation of fatty acids, B. Glucose-6-phosphatase deficiency, C. Pyruvate dehydrogenase deficiency, D. Urea cycle defect', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Reye syndrome is characterized by acute non-inflammatory encephalopathy and fatty degenerative liver failure. Reye syndrome typically occurs after a viral illness and is associated with the use of aspirin during the illness. The pathogenesis of Reye syndrome: Appears to involve mitochondrial injury resulting in dysfunction that inhibits oxidative phosphorylation and fatty-acid beta-oxidation', 'role': 'assistant'}]