This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti Microbial, Subject name: Pharmacology
[{'content': 'Not true about clofazamine - \nSelect and explain. \nA. Used in DLE, B. Causes ichthyosis and hyperpigmentation, C. Interferes DNA synthesis, D. Used in lepra reaction', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Used in DLE Clofazimineo Clofazimine is a leprostatic drug.o It acts by interfering the template function of DNA.o Adverse effects of clofazimine Skin - Reddish-black discolouration of skin, dryness of skin and itching, Discolouration of hair and body secretions, acneform eruptions and phototoxicity, conjuctival pigmentation. GIT- Enteritis with loose stools, nausea, abdominal pain, anorexia and weight loss.Remember - Clofazimine has antiinflammatory property can be used in lepra reaction.", 'role': 'assistant'}]