This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Stomach and Intestines, Subject name: Pediatrics
[{'content': 'A male infant presented with distension of abdomen shortly after birth with passing of less meconium. Subsequently a full-thickness biopsy of the rectum was performed. The rectal biopsy is likely to show: \nSelect and explain. \nA. Fibrosis of submucosa, B. Lack of ganglion cells, C. Thickened muscularis propria, D. Hyalinization of the muscular coat', 'role': 'user'}, {'content': 'Answer: B \nExplanation: b. Lack of ganglion cells(Ref: Nelson\'s 20/e p 1894-1897, Ghai 8/e p 285-286)"Whenever neonate presents with delayed passage of stool, Hirschsprung\'s disease should be suspected".', 'role': 'assistant'}]