This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General anatomy, Subject name: Anatomy
[{'content': 'All are true regarding hyper IgE syndrome except \nSelect and explain. \nA. Inheritance is as a single locus autosomal dominant trait with variable Expression, B. Coarse facial features, C. Recurrent staphylococcus abscess involving skin ,lungs, D. High IgE with low IgG ,IgA,and IgM', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ref Robbins 9/e p242 , Harrison 17/e p384;2061;2056;381 Hyper IgE Syndrome (HIES) is a rare primary immunodeficiency disease characterized by eczema, recurrent staphylococcal skin abscesses, recurrent lung infections, eosinophilia (a high number of eosinophils in the blood) and high serum levels of IgE But normal IgG ,IgM,IgA', 'role': 'assistant'}]