This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Streptococci, Subject name: Microbiology
[{'content': 'Streptococcus toxin which is responsible for connective tissue breakdown? \nSelect and explain. \nA. Hyaluronidase, B. Streptolysin O, C. Streptolysin S, D. Streptococcus pyogenic exotoxin', 'role': 'user'}, {'content': 'Answer: A \nExplanation: ANSWER: (A) HyaluronidaseREF: Jawetz Microbiology 24th Ed Ch 15Hyaluronidase splits hyaluronic acid, an important component of the ground substanceof connective tissue. Thus, hyaluronidase aids in spreading infecting microorganisms(spreading factor). Hyaluronidases are antigenic and specific for each bacterial or tissue source. Following infection with hyaluronidase-producing organisms, specific antibodies are found in the serum.', 'role': 'assistant'}]