This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cellular Pathology, Subject name: Pathology
[{'content': 'Which of the following can recognize dead material? \nSelect and explain. \nA. NET, B. Inflammasome, C. Necrosis, D. Toll-like receptor', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans. B. InflammasomeNOD-like receptors (NLRs) and the inflammasomeLocationCytosolic receptorsRecognizeNecrotic cells, ion disturbances (e.g., loss of k), urate crystal, and some microbial productsMechanism of actionActivates Caspase-1- activates IL-1- recruits leukocytes and induces feverRole in diseases* Periodic fever syndromes (autoinflammatory syndromes): Due to gain of function mutations* Obesity associated type 2 diabetes and atherosclerosis: Due to gain of function mutations* Inflammation in gout: Due to recognition of urate crystals by a class of NLRs', 'role': 'assistant'}]