This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'All are true about sulphonyl ureas except? \nSelect and explain. \nA. It blocks ATP sensitive K+ channels and increase insulin release, B. They have higher risk of causing hypoglycemia than meglitinides, C. They are used mainly in type 1 DM, D. Chlorpropamide can cause dilutional  hyponatremia', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Sulphonyl ureas are mainly used in Type 2 DM because Type 1 DM is characterized by autoimmune destruction of β - cells of pancreas and atleast 30% of\xa0β - cells should be present for sulphonyl ureas to be effective.', 'role': 'assistant'}]