This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Psychiatric Illness, Subject name: Pharmacology
[{'content': 'Which of the following adverse effect of levodopa is not blocked by carbidopa? \nSelect and explain. \nA. Vomiting, B. Hypotension, C. Psychosis, D. Tachycardia', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Levodopa - CARBIDOPA / BENSERAZIDE: Peripheral DOPA decarboxylase inhibitors. - So peripheral adverse effects will decrease - More L-DOPA will enter the brain and efficacy will increase The adverse effects are more due to deposition of DOPA in the brain. DOPA deposition leads to psychosis i.e. abnormal behaviour and dyskinesia. These effects cannot be decreased by carbidopa.', 'role': 'assistant'}]