This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Surgery
[{'content': "Crohn's disease is associated with polymorphisms in \nSelect and explain. \nA. NOD2/CARD 15 gene, B. P53 gene, C. Philadelphia chromosome, D. APC/Beta catenin", 'role': 'user'}, {'content': "Answer: A \nExplanation: Individuals with allelic variants of CARD15/NOD2 have a 40 fold relative risk for Crohn's disease compared with general population. Reference : Sabiston Textbook of Surgery, 19th Edition, page no = 1245.", 'role': 'assistant'}]