This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Gynaecology & Obstetrics
[{'content': 'Glomerular filtration rate increases in pregnancy by \nSelect and explain. \nA. 15%, B. 25%, C. 40%, D. 50%', 'role': 'user'}, {'content': "Answer: D \nExplanation: Both the glomerular filtration rate (GFR) and renal plasma flow increase early in pregnancy. The GFR increases as much as 25 percent by the second week after conception and 50 percent by the beginning of the second trimester(Ref: William's Obstetrics; 25th edition)", 'role': 'assistant'}]