This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Congenital Anomalies of the CNS, Subject name: Pediatrics
[{'content': "Administration of which of the following can prevent neural defects in newborn? \nSelect and explain. \nA. Folic acid, B. VitBl'2, C. Pyridoxine, D. Vitamin C", 'role': 'user'}, {'content': "Answer: A \nExplanation: Ref: Nelson's Textbook of Pediatrics. 19th Edition.Explanation:Prevention of Neural tube defectsAll women of childbearing age and who are capable of becoming pregnant take (1.4 mg of folic acid daily.In high-risk women (previously affected child), supplementation should be started with 4 mg of folic acid daily, beginning i mo before the time of the planned conception.Certain drugs that antagonize folic acid increase the risk of myelomeningoceleTrimethoprimCarbamazepinePhenytoinPhenobarbitalPrimidoneValproic acid", 'role': 'assistant'}]