This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General physiology, Subject name: Physiology
[{'content': 'Special transmembrane proteins which make up gap junctions is called as \nSelect and explain. \nA. Cadherins, B. Occludins, C. Connexons, D. Claudins', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Communicating junctions (gap junctions) mediate the passage of chemical or electrical signals from one cell to another. The junction consists of a dense planar array of 1.5- to 2-nm pores (called connexons) formed by hexamers of transmembrane proteins called connexins. These pores permit the passage of ions, nucleotides, sugars, amino acids, vitamins, and other small molecules; the permeability of the junction is rapidly reduced by lowered intracellular pH or increased intracellular calcium. Gap junctions play a critical role in cell-cell communication.Ref: Robbin&;s; 9th edition; Chapter 1; The Cell as a Unit of Health and Disease', 'role': 'assistant'}]