This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Medicine
[{'content': 'Megaloblastic anaemia may be caused by all of the following except \nSelect and explain. \nA. Phenytoin, B. Methotrexate, C. Pyrimethamine, D. Amoxicillin', 'role': 'user'}, {'content': 'Answer: D \nExplanation: <p>Phenytoin decreases folate absorption & increases its excretion causing megaloblastic anaemia.</p><p>Methotrexate is folate antagonist </p><p>Pyrimethamine in high doses causes megaloblastic anaemia,especially in those with marginal folate stores.</p><p>Reference :Tripathi essentials of medical pharmacology 7th edition</p>', 'role': 'assistant'}]