This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': 'Which vitamin deficiency is responsible for neonatal seizure – \nSelect and explain. \nA. Pyridoxine, B. Vitamin C, C. Thiamine, D. Cobalamin', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Pyridoxine (Vitamin B6) dependency with seizures is an autosomal recessive condition.\nIt is due to GABA deficiency in the brain, which is presumbly caused by decreased activity of GAD (glutamic acid decarboxylase).\nAdministration of large doses of pyridoxin usually results in a dramatic improvement of both seizures and EEG abnormalities, as pyridoxin acts as a cofactor for GAD and improves its activity.', 'role': 'assistant'}]