This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Anaesthesia
[{'content': 'Intravenous regional anaesthesia is contraindicated in \nSelect and explain. \nA. Sickle cell disease, B. Thalassemia, C. Hereditary spherocytosis, D. G6PD deficiency', 'role': 'user'}, {'content': 'Answer: A \nExplanation: As tourniquet application can precipitate sickling and hypoxia, IVRA is contraindicated in sickle cell anemia.', 'role': 'assistant'}]