This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Cardiac conduction defect seen with Tricyclic antidepressants are due to- \nSelect and explain. \nA. NE & serotonin uptake inhibitor, B. Antimuscarinic action on hea, C. Only NE uptake inhibition, D. Both NE uptake inhibition and antimuscarinic action on hea', 'role': 'user'}, {'content': "Answer: D \nExplanation: Ans. is 'd' i.e., Both NE uptake inhibition and antimuscarinic action on hea o The commonest cardiovascular effect of tricyclic antidepressant overdose is sinus tachycardia, which is attributable to the inhibition of norepinephrine reuptake and the anticholinergic action.", 'role': 'assistant'}]