This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: FMGE 2019, Subject name: Pharmacology
[{'content': 'Which of the following anti-epileptic drug has the highest teratogenic potential? \nSelect and explain. \nA. Valproate, B. Carbamazepine, C. Phenytoin, D. Lamotrigine', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Anti epileptic with highest risk of teratogenicity - Valproate - causes neural tube defects Anti epileptic with lowest risk of teratogenicity- Lamotrigine Levetiracetam', 'role': 'assistant'}]