This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Transcription, Subject name: Biochemistry
[{'content': "Which of the following statement is TRUE about iron response element? \nSelect and explain. \nA. Stem loop structure in the messenger RNA, B. Located at the 5' untranslated region(UTR) of transferrin mRNA, C. Located at the 3' untranslated region(UTR) of ferritin mRNA, D. IRE-binding protein causes degradation of IRE", 'role': 'user'}, {'content': "Answer: A \nExplanation: mRNAs of ferritin and tfR 1 contain a stem-loop structure known as Iron Response Element (IRE). IRE of ferritin mRNA is located at its 5' UTR. (Ferritin ->Five) - option c is wrong IRE of transferrin receptor is located at its 3'UTR. (TfR ->Three) - option b s wrong. IRP-IRE interaction prevents the translation of ferritin mRNA. IRP-IRE interaction stabilises the mRNA of transferrin receptor-more intracellular iron absorption.- option d is wrong.", 'role': 'assistant'}]