This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'The histologic entity that has the worst prognosis in interstitial lung disease is: \nSelect and explain. \nA. Non-specific interstitial pneumonia, B. Desquamative interstitial pneumonia, C. Acute interstitial pneumonia, D. Usual interstitial pneumonia', 'role': 'user'}, {'content': "Answer: C \nExplanation: Ans: c (Acute interstitial pneumonia)Ref: Rosai and Ackerman's Surgical Pathology 9th ed Pg. 377, Harrison 18th ed chp 261Acute Interstitial Pneumonia (Hamman-Rich Syndrome)* A fulminant form of lung injury characterized by idiopathic ARDS and organizing diffuse alveolar damage by lung biopsy.* The onset is usually abrupt following a prodromal illness.* CXR - Diffuse, bilateral, air-space opacification.* HRCT - bilateral, patchy, symmetric areas of ground-glass attenuation & areas of air-space consolidation. A predominantly subpleural distribution may be seen.* The mortality rate is high (>60%), most patients die within 6 months.* Treatment is supportive, glucocorticoid therapy role not clear.", 'role': 'assistant'}]