This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous (Bio-Chemistry), Subject name: Biochemistry
[{'content': "Gaucher's disease is due to enzyme deficiency of \nSelect and explain. \nA. Glucocerebrosidase, B. Sphingomyelinase, C. Hexosaminidase, D. Ceramidase", 'role': 'user'}, {'content': 'Answer: A \nExplanation: (A) Glucocerebrosidase# Gaucher disease refers to a duster of autosomal recessive disorders resulting from mutations in the gene encoding glucocerebrosidase. This disease is the most common lysosomal storage disorder.> This affected gene encodes glucocerebrosidase, an enzyme that normally cleaves glucose residue from ceramide> As a result, glucocerebroside accumulates principally in the phagocytic cells of the body but in some forms also in the central nervous system.> Glucocerebrosides derived mainly from the cell membranes of leukocytes and erythrocytes.', 'role': 'assistant'}]