This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Orthopaedics
[{'content': 'Which of these muscles undergoes wasting first in osteoarthritis knee- \nSelect and explain. \nA. Quadriceps only, B. Hamstrings only, C. Gastronemius, D. All of the above', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Muscle atrophy particularly involves the quadriceps muscle.\nAll periarticular muscles around the knee joint may undergo wasting in advanced osteoarthritis knee.\nHowever muscle atrophy particularly involves the quadriceps which is the earliest muscle to undergo wasting.\nIn patients with osteoarthritis knee, quadriceps strengthening exercise form an important management component to protect the articular cartilage from stress.', 'role': 'assistant'}]