This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy, Subject name: Pharmacology
[{'content': 'Combination of amoxicillin with clavulanic acid is active against all the following organisms except \nSelect and explain. \nA. MRSA, B. Pencillinase producing staph aureus, C. Pencillinase producing N.gonorrhea, D. Beta lactamase producing E. Coli', 'role': 'user'}, {'content': 'Answer: A \nExplanation: MRSA occurs due to altered Pencillin binding proteins There fore cannot be replaced by beta lactamase inhibitor like clavulanic acid Refer GG 1497', 'role': 'assistant'}]