This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Substance abuse, Subject name: Psychiatry
[{'content': '1st line treatment for smoking cessation includes \nSelect and explain. \nA. Noriptyline, B. Clonidine, C. Varenicline, D. Buspirone', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Varenicline -ALPA 4 BETA 2 paial agonist for nicotinic receptors is the new 1st line treatment for smoking dependence. Ref: Essentials of postgraduate psychiatry By JN Vyas 1st ed Pg 351', 'role': 'assistant'}]