This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'A patient with pancreatic malignancy presents with lethargy, yellow urine and pruritus. The probable location of the tumor is: \nSelect and explain. \nA. Head of the pancreas, B. Body of the pancreas, C. Tail of the pancreas, D. Pancreatic malignancy with liver metastasis', 'role': 'user'}, {'content': "Answer: A \nExplanation: Obstructive jaundice is a frequent feature when the cancer is located in the head of pancreas. The symptoms are abdominal discomfo, pruritus, lethargy, and weight loss. Physical signs: Jaundice and cachexia, and scratch marks. 25% have a palpable gall bladder (Courvoisier's sign). Ref: Harrison, Edition -18, Page-789", 'role': 'assistant'}]