This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pathology
[{'content': "Which of the following is not true about medullary carcinoma of thyroid ? \nSelect and explain. \nA. Origin is from 'C' cells of thyroid, B. Component of MEN- 1, C. Multicentric in origin, D. Amyloid deposition", 'role': 'user'}, {'content': 'Answer: B \nExplanation: Medullary carcinoma of thyroid is a neuroendocrine neoplasm which is multicentric and derived from C cells of thyroid. It is characterised by acellular amyloid deposits derived from calcitonin in stroma of the cells. It is a component of MEN 2A or MEN 2B and not MEN 1. Ref: Robbins and cotrans 9e Pg 1099 Ref IMG', 'role': 'assistant'}]