This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Dosage of drug is determined by following except ? \nSelect and explain. \nA. Volume of distribution, B. Halflife, C. Lipid solubility, D. None', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans. is \'None\' o Loading dose is governed by volume of distribution and volume of distribution is affected by lipid solubility. o Maintenance dose is governed by clearance (excretion) of drug and half life. o For one option go ahead for option b ie half life because : "Clearance is the most impoant factor for maintenance dose".', 'role': 'assistant'}]