This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Medicine
[{'content': "Primary hyperaldosteronism (Conn's syndrome) is characterized by- \nSelect and explain. \nA. High renin, high aldosteorone, B. Low renin, high aldosterone, C. Low renin, low aldosterone, D. High renin, low aldosterone", 'role': 'user'}, {'content': 'Answer: B \nExplanation: high aldosterone and low renin because as there is hypo secretion of renin that fails to increase appropriately during volume depletion and hyper secretion of aldosterone that does not suppress in response to volume expansion (Harrison 17 pg 2260)', 'role': 'assistant'}]