This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.V.S, Subject name: Pediatrics
[{'content': 'A premature infant is born with a patent ductus aeriosus. Its closure can be stimulated by administration of \nSelect and explain. \nA. Prostaglandin analogue, B. Estrogen, C. Anti-estrogen compounds, D. Prostaglandin inhibitors', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Before 2 weeks of gestation indomethacin 0.2mg/kg dose orally every 12-24 hr for 3 doses. Ref : Ghai essential pediatrics,eighth edition P.no: 419', 'role': 'assistant'}]