This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Surgery
[{'content': "Hallmark of Barrett's epithelium is \nSelect and explain. \nA. Mucus secreting goblet cells, B. Transitional columnar epithelium, C. Stratified squamous epithelium, D. Acid producing parietal cells", 'role': 'user'}, {'content': "Answer: A \nExplanation: Barrett's oesophagus is a metaplastic change in the lining mucosa of the oesophagus in response to chronic gastro-oesophageal refluxThis adaptive response involves a mosaic of cell types, probably beginning as a simple columnar epithelium which becomes 'specialised' with time. The hallmark of 'specialised' Barrett's epithelium is the presence of mucus-secreting goblet cells (intestinal metaplasia).Ref: Bailey and Love 27e pg: 1081", 'role': 'assistant'}]