This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'A 50-year-old male presented with signs and symptoms of restrictive heart disease. A right ventricular endo-myocardial biopsy revealed deposition of extracellular eosinophilic hyaline material. On transmission electron microscopy, this material is most likely to reveal the presence of- \nSelect and explain. \nA. Non branching filaments of indefinitive length, B. Cross banded fibres with 67 m periodicity, C. Weber Palade bodies, D. Concentric whorls of lamellar structures', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Restrictive cardiomyopathy along with deposition of extracellular eosinophilic hyaline material suggest the diagnosis of Amyloidosis\nMyocardial involvement with amyloid is a common cause of secondary restrictive cardiomyopathy.\xa0Amyloid is a pathological proteinaceous substance deposited between cells in various tissues and organs of the body.\nWith the light microscopic and standard tissue stains amyloid appears as an amorphous, eosinophilic, hyaline extracellular substance, that with progressive accumulation encroaches on and produces pressure atrophy of adjacent cells.', 'role': 'assistant'}]