This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Surgery
[{'content': 'Pheochromocytoma is associated with \nSelect and explain. \nA. Von Hippel Lindau syndrome, B. MEN-I, C. Multiple neurofibromatosis, D. Insulinomas', 'role': 'user'}, {'content': 'Answer: A \nExplanation: (A) Von Hippel Lindau syndrome # Pheochromocytoma is a rare catecholamine-secreting tumor derived from chromaffin cells. Tumors that arise outside the adrenal gland are termed extra-adrenal pheochromocytomas or paragangliomas. Because of excessive catecholamine secretion, pheochromocytomas may precipitate life-threatening hypertension or cardiac arrhythmias. If the diagnosis of a pheochromocytoma is overlooked, the consequences could be disastrous, even fatal; however, if a pheochromocytoma is found, it is potentially curable.> Pheochromocytomas are rare, reportedly occurring in 0.05-0.2% of hypertensive individuals. Patients may be completely asymptomatic. A retrospective study from the Mayo Clinic revealed that in 50% of cases, the diagnosis was made at autopsy. Approximately 10% of pheochromocytomas are discovered incidentally. Pheochromocytomas may occur in certain familial syndromes, including multiple endocrine neoplasia (MEN) 2A and 2B, neurofibromatosis, and von Hippel-Lindau (VHL) disease.> VHL syndrome is associated with pheochromocytomas, cerebellar hemangioblastomas, and renal cell carcinoma', 'role': 'assistant'}]