This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Beta blocker that can be used in renal failure is all except- \nSelect and explain. \nA. Propranolol, B. Pindolol, C. Sotalol, D. Oxyprenolol', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans. is \'c\' i.e., Sotalol "Sotalol is not metabolized in liver, excretion is predominantly by the kidney in the unchanged form". - Katzung 101Ve p. 229 Since it is primarly excreted in urine, it should not be used in renal failure. 0-blockers which are primarily excreted by kidney and should not be given in renal failure --> Atenolol, Sotalol, nodolol About other options Approximately 50% of pindolol is metabolized in liver, the remainder of the drug is excreted unchanged in urine - - Goodman Gillman o Propranolol and oxprenolol are mainly metabolized in liver.', 'role': 'assistant'}]