This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Systemic Bacteriology Pa 1 (Gram Positive Cocci, Gram Negative Cocci), Subject name: Microbiology
[{'content': 'Transfer of drug resistance in staphylococcus is by- \nSelect and explain. \nA. Transduction, B. Transformation, C. Conjugation, D. Transfection', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Option 1, 3 Transduction Transfer of bacterial genes from one bacteria to another by bacteriophage. Production of b-lactamase is usually controlled by plasmids MRSA: Production of PBP-2a is by chromosomally coded by mec A gene which alters PBP to PBP-2a Option 2 Transfer of drug resistance in staphylococcus is not done by Transformation. Transformation Process of random uptake of free or naked DNA fragment from the surrounding medium by a bacterial cell and incorporation of this molecule into its chromosome in a heritable form. Eg :: Streptococcus, Bacillus, Haemophilus, Neisseria, Acinetobacter and Pseudomonas. Option 4 Transfection Process of aificially introducing nucleic acids (DNA or RNA) into cells, utilizing means other than viral infection.', 'role': 'assistant'}]