This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
[{'content': 'Type I hypersensitivity is mediated by which of the following immunoglobulins ? \nSelect and explain. \nA. Ig A, B. Ig G, C. Ig M, D. Ig E', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Harshmohan textbook of pathology 7th edition. *type 1 or anaphylactic or atopic reaction mediated by humoral antibodies of IgE type or reagin antibodies in response to antigen.', 'role': 'assistant'}]