This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Atopy in hypersensitivity is - \nSelect and explain. \nA. Systemic type I hypersensitivity, B. Systemic type II hypersensitivity, C. Local type I hypersensitivity, D. Local type II hypersensitivity', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Type I hypersensitivity occurs in two forms :\n1. Anaphylaxis\n2. Atopv\n→\n→\nAcute, potentially fatal, systemic.\nChronic. Nonfatal. Localized.\nRemember\n\xa0Mast cells are the most important cells in type 1 hypersensitivity.\nO Eosinophils are the most important cells in the late phase reaction of type I hypersensitivity,\n\xa0Histamine is the most important mediator in type 1 hypersensitivity.\n\xa01L-4 is particularly important, it is essential for turning on IgE secreening B cells.\n\xa0PAF is the most important cytokine in the initiation of late phase reaction.\nMost potent eosinophilic activating cytokine is 1L-5.', 'role': 'assistant'}]