This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'Which of the following is granted orphan drug status for the treatment of Dravet’s syndrome? \nSelect and explain. \nA. Stiripentol, B. Icatibant, C. Pitolisant, D. Tafamidis', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Stiripentol\nStiripentol increases GABA transmission. It is granted orphan drug status for the treatment of Dravet’s syndrome (Severe myoclonic epilepsy in infants).\nIcatibant is a bradykinin B2 receptor antagonist. It is used for acute attacks of hereditary angioedema in adults with C1-esterase inhibitor deficiency.\nPitolisant (a/k/a Tiprolisant) is a inverse agonist of H3 receptor. It is under trial for schizophrenia and Parkinson’s disease.\nTafamidis stabilizes the correctly folded tetrameric form of TTR. It is used in familial amyloid polyneuropathy.', 'role': 'assistant'}]