This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Urology, Subject name: Anatomy
[{'content': 'What is true about carcinoma bladder - \nSelect and explain. \nA. Common in smokers, B. Mostly adenocarcinoma, C. Common in females than in males, D. Pain in suprapubic region is the first symptom', 'role': 'user'}, {'content': "Answer: A \nExplanation: Carcinoma Urinary Bladder More common in whites, higher socio-economic status and in males in 6th and 7th decade. 75% are localised to bladder and 25% have spread to regional nodes or distant sites at the time of presentation Most tumors develop at trigone & adjacent poster lateral wall with urethral involvement Tumors tend to be multifocal in bladder Clinical features MC symptom : painless hematuria (85% cases) Hematuria is gross or microscopic, intermittent rather than constant Vesical irritability : Frequeny, urgency and dysurea Bone pain & abdominal pain in advanced disease Ref: Smith's 18th edition Pgno : 312", 'role': 'assistant'}]