This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Pathology
[{'content': 'A 50 year old male presented with blurring of vision. Urine examination showed proteinuria. Fundus examination showed dot and blot haemorrhages, microaneurysm and cotton wool spots. Histopathology pic of kidney given below. Your diagnosis? \nSelect and explain. \nA. Kimmelstiel Wilson nodules, B. Crescents, C. Amyloid, D. Segmental sclerosis', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. (a) Kimmelstiel Wilson nodules(Ref: Robbins 9th edp 1118)Diabetic Nephropathy:The renal lesions include mainly: Glomerular lesions:*Basement membrane thickening and increased mesangial matrix in patients*Diffuse glomerulosclerosis#Increase in mesangial matrix associated with PAS+ basement membrane thickening, eventually obliterates mesangial cells, found in most individuals with disease of more than 10 years duration*Nodular glomerulosclerosis#Intercapillary glomerulosclerosis or Kimmelstiel- Wilson diseas', 'role': 'assistant'}]