This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Physiology
[{'content': 'Effect of coisol \nSelect and explain. \nA. Decreased bone matrix, B. Increased bone mattix, C. Increases lymphocytes, D. Increases RBCs', 'role': 'user'}, {'content': 'Answer: A \nExplanation: The principal glucocoicoid produced by the zona fasciculata of the adrenal coex. It promotes gluconeogenesis and lipolysis, suppresses protein synthesis, inhibits inflammatory and immune responses, and has mild mineralocoicoid (for example, hypernatremic, kaliuretic, antidiuretic) effects. Most plasma coisol is bound to transcoin and albumin. Synthetic coisol administered as a drug is usually known by the alternative name hydrocoisone.Ref: Ganong&;s review of medical physiology;24th edition; page no-362', 'role': 'assistant'}]