This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Inflammatory bowel disease, Subject name: Surgery
[{'content': 'Sulfasalazine exes its primary action in ulcerative colitis by : \nSelect and explain. \nA. Folic acid synthesis, B. Formation of prostaglandins (PG), C. Inhibition of NF-KB Activation, D. Formation of interleukins', 'role': 'user'}, {'content': 'Answer: C \nExplanation: MOA* Inhibition of NF-KB Activation* Inhibition of PG synthesis* Scavenging of Free radicals 5-ASA compounds exe its local anti-inflammatory effect by inhibiting leukotriene production (PG synthesis) by inhibition of 5-lipooxygenase activity; also inhibits the production of IL-1 and TNF. Commonly Used 5-ASA Formulations in IBD Sulfasalazine Oral mesalamine agents Azo compounds: Balsalazide, Olsalazine', 'role': 'assistant'}]