This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Takotsubo Cardiomyopathy and Brugada Syndrome, Subject name: Medicine
[{'content': 'What type of mutation is most commonly associated with Brugada syndrome? \nSelect and explain. \nA. Gain of function mutation, B. Loss of function mutation, C. Antimorphic mutation, D. Lethal mutation', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Brugada syndrome Loss of function mutation SCN5A mutation', 'role': 'assistant'}]