This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Main abnormality in beta-thalassemia minor is: March 2011 \nSelect and explain. \nA. Increased HbA2, B. Severely increased, C. HbFSevere anemia, D. All of the above', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. A: Increased HbA2 Haemoglobin electrophoresis in beta-thalassemia minor usually reveals an increase in HbA2 (alpha2, gamma2) to 4-8% of the total hemoglobin (normal 2.5%)', 'role': 'assistant'}]