This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Glucose Transpo, Subject name: Biochemistry
[{'content': 'Which of the following is defective in renal glycosuria: \nSelect and explain. \nA. GLUT- 1, B. GLUT- 2, C. SGLT- 1, D. SGLT- 2', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Renal Glycosuria (also called Familial Renal Glucosuria or Glycosuria ) Blood glucose is normal, But still Glucose appears in urine. It is due to defect/mutation in SGLT-2, which is major glucose transpoer (90% glucose reabsorption) present in kidneys for the reabsorption and transpo of Glucose (see fig below). Mutation in SGLT-1 (10% glucose reabsoption) leads to glucose-galactose malabsorption', 'role': 'assistant'}]