This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Dental
[{'content': 'All the following antimicrobial agents are used topically except – \nSelect and explain. \nA. Clotrimazole, B. Griseofulvin, C. Nystatin, D. Miconazole', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Griseofulvin is used systemically for dermatophytosis. It is ineffective topically.\nPolyene\n\nAmphotericin B → Topically as well as systemically (oral, iv intrathecally.\nNystatin, Hamycin, Natamycin (Pimaricin) → Topically.\n\nHetrocyclic benzofuran\n\nGriseofulvin → Systemically (oral)\n\nImidazoles\n\nClotrimazole, econazole, miconozole, oxiconazole → Topical.\nKetoconazole Systemically (oral) and topically.\n\nTriazoles\n\nFluconazole, voriconazole → systemically (iv., oral) and itraconozole → systemically (orally).\n\nAllylamine\n\nTerbinafine → Systemically (oral) and topically.\n\nNote\n\nAmphotericin B, ketoconazole and terbinafine are used systemically as well as topically.', 'role': 'assistant'}]