This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: miscellaneous, Subject name: Pathology
[{'content': 'Werner disease is associated with?- \nSelect and explain. \nA. Intestinal polyps, B. Multiple cancer, C. Lax joints, D. Premature ageing', 'role': 'user'}, {'content': 'Answer: D \nExplanation: DNA repair mechanisms are defective in diseases such as Werner syndrome and ataxia-telangiectasia. Werner syndrome (WS), also known as "adult progeria", is a rare, autosomal recessive disorder which is characterized by the appearance of premature aging. Werner syndrome is named after the German scientist Otto Werner.', 'role': 'assistant'}]