This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.N.S, Subject name: Pharmacology
[{'content': 'Dysphoria caused by opiates is mediated by which receptor? \nSelect and explain. \nA. mu, B. kappa, C. delta, D. sigma', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans. b. kappa (Ref: KDT 7/e p478-80, 6/e p462)Dysphoria caused by opiates is mediated by kappa receptor.Actions ascribed to Opioid Receptorsm (mu) k (kappa)d (delta)* Physical dependence (morphine type)* Miosis* Constipation (m2)* Analgesia (supraspinalm 1 + spinal m2)* Respiratory depression (m2)* Euphoria* Sedation* (PM CARES)* Dysphoria, pscychomimetic* Miosis (lower ceiling)* Analgesia (Spinal k1 , supraspinal k3)* Respiratory depression (lower ceiling)* Diuresis* Sedation* Physical dependence (nalorphine type)* Reduced Gl motility* (DMARDS)* Analgesia (Spinal + affective component of supraspinal)* Respiratory depression* Affective behavior* Reinforcing actions* Reduced Gl motility', 'role': 'assistant'}]