This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Pharyngeal Arches, Subject name: Anatomy
[{'content': 'Digeorge syndrome is due to defect of? \nSelect and explain. \nA. pouch 1, B. pouch 2, C. pouch 3 and 4, D. pouch 5', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Digeorge syndrome is due to defect of pouch 3 and 4. Pouch 3 compromised - No thymus - CMI decreases - Severe bacterial infections Pouch 3 & 4 compromised - absent or poorly developed parathyroid - low PTH - Hypocalcemia.', 'role': 'assistant'}]