This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Pharmacokinetics, Subject name: Pharmacology
[{'content': 'Which of the following metabolic reactions is not catalysed by microsomal enzymes? \nSelect and explain. \nA. Glucuronidation, B. Acetylation, C. Oxidation, D. Reduction', 'role': 'user'}, {'content': 'Answer: B \nExplanation: PHASE 1 * Oxidation * Reduction All are catalysed by microsomal enzymes PHASE 2 * Glucuronidation * Acetylation * Methylation All are catalyzed by non microsomal enzymes except glucuronidation which is catalysed by microsomal enzymes.', 'role': 'assistant'}]