This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': 'True about infantile tremor syndrome – \nSelect and explain. \nA. Hyperpigmentation of extremities, B. Cortical atrophy, C. Self limiting disorder, D. All of these', 'role': 'user'}, {'content': 'Answer: D \nExplanation: "Infantile tremor syndrome is a self-limiting disorder characterised by acute & gradual onset with neural & psychomotor changes, pigmentary disturbances of hair & skin, pallor & tremors".\nInfants Tremor Syndrome \n\nFound in infants & young children\nEtiological possibilities are malnutrition, Vit. B12 deficiency & viral infections but none have been conclusively proven.\nBoys are twice as commonly affected as girls.\nMost cases occur in summer months in children belonging to the low socioeconomic group.\nThere are 3 clinical phases - prodromal, tremor & post tremor phases.\nThere is hyperpigmentation, especialy over dorsum of hands, feet, knees ankles, wrists, terminal phalanges & thigh.\nAt times there may be fever, upper respiratory tract infection, diarrhoea, edema, hepatomegaly & a tremulous cry.\nTremor are coarse, fast, 6-12 cycles per second, of low amplitude, initially intermittent but become continuous later on.\nThere is mild to moderate pallor.\nPnenumoencephaly reveals cortical atrophy. CT scan shows no abnormalities or mild atrophy. - O.P. Ghai.\nSubnormal intelligence is only long term sequele.\nTreatment is largely empirical, symptomatic & supportive.', 'role': 'assistant'}]