This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Pathology
[{'content': 'The peripheral smear of Hereditiary spherocytosis will show spherocytes - \nSelect and explain. \nA. Usually of same size as RBCs, B. Reticulocytosis absent, C. Anemia is negligible, D. Smaller size than RBCs', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Various mutations involving membrane skeletal proteins weakens interactions b/w proteins and cause red cells to lose memb fragments . This causes decrease in size of the spherocytes compared to normal RBCs Ref: Robins 9/e pg:632', 'role': 'assistant'}]