This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrine System, Subject name: Physiology
[{'content': 'Thyroxine binding globulin (TBG) is increased in: \nSelect and explain. \nA. Glucocoicoid therapy, B. Nephrotic syndrome, C. Pregnancy, D. Cancer chemotherapy', 'role': 'user'}, {'content': 'Answer: C \nExplanation: TBG concentration increases in (conditions of high estrogen levels) such as: pregnancy oral contraceptives. TBG concentration is decreased by: Hormones ( androgens, glucocoicoids;) Malnutrition nephrotic syndrome cancer chemotherapy. Drugs, such as phenytoin, salicylates.', 'role': 'assistant'}]