This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Etoposide acts by - \nSelect and explain. \nA. Inhibition of dihydrofolate, B. Inhibition of topoisomerase, C. Inhibition of purine synthesis, D. Inhibition of protein synthesis', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., Inhibition of topoisomerase o Etoposide and teniposide are natural anticancer drugs. o They act by inhibiting topoisomerase II that leads to DNA strand breakage.", 'role': 'assistant'}]