This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'Anticoagulant not requiring routine coagulation profile monitoring post dosing is: \nSelect and explain. \nA. Warfarin, B. Dabigatran etexilate, C. Argatroban, D. Phenprocoumon', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ref. KDT. Page. 617\nDabigatran:\n\nDabigatran, the main active principle in plasma, is a rapid-acting competitive and reversible direct inhibitor of thrombin.\nDabigatran inhibits free thrombin, fibrin-bound thrombin and thrombin-induced platelet aggregation.\nIt may increase INR but this laboratory parameter is relatively insensitive to the activity of dabigatran -\xa0 monitoring is not required\nCYP450 enzymes are not involved in the metabolism of dabigatran thus is not expected to interact with drugs metabolized by CYP isoenzyme\nMainly excreted in urine (85%)\nThe most common adverse reactions include dyspepsia or gastritis-like symptoms.', 'role': 'assistant'}]