This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Autosomal recessive polycystic kidney disease is characterised by the altered expression of: \nSelect and explain. \nA. Polycystin, B. Nephrocystin, C. Uromodulin, D. Fibrocystin', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Fibrocystin (polyductin) gene mutation is seen in autosomal recessive polycystic kidney disease. Note: Polycystin mutation is associated with autosomal dominant polycystic kidney disease. Nephrocystin is related to nephronophthisis. Uromodulin mutation is seen in medullary cystic kidney disease. Ref: Harrisons principles of internal medicine, 18th edition, Page: 2356.', 'role': 'assistant'}]