This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Which one of the following drugs does not undergo hepatic first-pass effect ? \nSelect and explain. \nA. Propranolol, B. Lidocaine, C. Insulin, D. Morphine', 'role': 'user'}, {'content': 'Answer: C \nExplanation: - Except for Insulin, all the three options undergo high first pass metabolism.', 'role': 'assistant'}]