This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
[{'content': 'Not true about polycystic kidney disease is - \nSelect and explain. \nA. Autosomal dominant, B. Proteinuria <2gm/day, C. Leads to CRF, D. Decompression of cyst leads to normal renal function', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Decompression or uncapping of cysts (Rovsings operation) is of no use in preserving the renal function.\n\nPolycystic kidney disease \n\nIs of 2 types:\n\nAdult PKD\nInheritance is AD\nDisease manifests itself in adult life.\nInfantile PKD\n\xa0Inheritance is AR\nDisease manifests in infancy as severe renal failure and life expectancy is short.\n\nAdult PKD\n\nAlmost always bilateral (95%)\nDisease ordinarily does not manifest itself before 40 yr of age.\nPts. of APKD have increased frequency of cysts in liver (30%), Pancreas, Spleen"; ovaries & berry aneurysm of cerebral arteries.\n\nPathology -\n\nthe kidney is enlarged 3 to 4 times.\nIt is studded all over with cysts.\nCysts are distributed evenly throughout the cortex & medulla.\nContent of the cyst varies but its not urine.\nRenal tissue is progressively replaced by cysts leading to CRF.\n\nClinical Presentation\n\nMass\nPain\nHypertension (70 to 80% of cases)\nHenzaturia\nInfection\nUremia\nUrine examination\nhigh output of urine,\nlow specific gravity.\nIt may contain traces of albumin\nIt ultimately leads to CRF and renal transplantation is the only definite t/t.', 'role': 'assistant'}]