This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anatomy of skin, Subject name: Dental
[{'content': 'Cells as they approach towards stratum corneum shows the following features \nSelect and explain. \nA. Cells become flat and dehydrated, B. Nucleus lost, C. Loss of mitotic and metabolic activity, D. All of the above', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Stratum corneum It is the outer most layer, which serves as a mechanical barrier between the epidermis and the environment. It is Composed primarily of protein-rich corneocytes ("bricks"; contain NO nuclei; keratin filaments attached to cornified envelope) embedded in a lipid matrix ("moar," cornified lipid envelope). It Serves as a barrier to water loss (conditions that peurb the skin |transepidermal water loss) and toxins/infectious agents. Ref:- Review of Dermatology by Alikhan; pg num:-5', 'role': 'assistant'}]