This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'Following are progesterone related side effects with hormone replacement therapy except \nSelect and explain. \nA. Acne, B. Leg cramps, C. Irritability, D. Constipation', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Leg cramps are oestrogen related side effects with HRT.', 'role': 'assistant'}]