This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Which of the following is a long-acting beta 2 against - \nSelect and explain. \nA. Orciprenaline, B. Penoterol, C. Pexbaterol, D. Salmeterol', 'role': 'user'}, {'content': 'Answer: D \nExplanation: β2,-agonists used in Asthma 1. Short acng → Salbutamol, terbutaline\n\n2. Long acng → Salmeterol, formoterol \xa0Bambuterol is a prodrug of terbutaline. It is slowly hydrolysed by pseudocholineterase.\n\xa0Short-acting β2-agonists produce bronchodilation within 5 min and action lasts for 2-6 hrs →\nare used to abort and terminate acute asthma, but are not suitable for prophylaxis,\n\xa0Salmeterol is delayed acting, can be used for prophylaxis only, while formoterol is fast acng and long acng can be used for both prophylaxis and acute aack.\nSalbutamole & Terbutaline →\nOnly for acute attack Salmeterol →\nOnly for prophylaxis Formoterol → Both for prophylaxis and acute attack\n\n\xa0Long acting β2-agonists (salmeterol & formoterol) are superior to short acting β2-agonists (salbutamol & terbutaline),\n\nand equivalent to inhaled anticholinergics in COPD. NoteFor one opon go ahead with opon ‘d’, i.e. adrenaline because amongst the given opons,\nadrenaline is shortest acng (60 - 90 minutes).\n\n\xa0Salmeterol and formoterol are long-acting β2,-agonists.\n\n\xa0Their lipophilic action is responsible for longer action → Lipophilic side chain anchors the drug in membrane adjacent to the receptor, slowing', 'role': 'assistant'}]