This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'Best Indicator of Ovarian reserve \nSelect and explain. \nA. FSH, B. Estradiol, C. LH, D. FSH/LH Ratio', 'role': 'user'}, {'content': 'Answer: A \nExplanation: None of the ovarian reserve tests currently in use are accurate predictors for pregnancy\nWith current methods, basal FSH concentration is simplest and most widely used to test ovarian reserve. Levels greater than 10 IU/L (10-20 IU/L) have high specificity (80-100%) for predicting poor ovarian response to ovulation. Serum FSH levels vary significantly across the cycle hence FSH is best measured during the early follicular phase ( cycle day 2-4).\nBasal serum estradiol concentration has little value as ovarian reserve test.\nAMH: Antimullerian hormone is produced from preantral and small antral follicles hence AMH levels are gonadotropin-independent and exhibit little variation within and between menstrual cycles. AMH threshold levels (0.2-0.7ng/ml) has 40-97% sensitivity, 70-92% specificity, 22-88% PPV and 97-100% NPV for predicting poor response to stimulation (<3 follicles or < 2-4oocytes).', 'role': 'assistant'}]