This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': 'Which of the following is true regarding Typhoid in children : \nSelect and explain. \nA. Leukochyosis is characteristic, B. Encephalitis is common, C. Mild splenomegaly is usual, D. Urine culture is positive in 4 to 6 days', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Typhoid in children :\n\nSplenomegaly is usual and seen in about 90% of patients. The spleen is palpable for 1 of 2 cm below the costal margin\xa0(Mild Splenonzegaly)\xa0in over 2/3 rd of patients.\nBlood counts usually show a normal or low leukocyte count (not leuhocytosis). There is always a moderate neutropenia leading to relative lymphocytosis.\nNeurological complications are uncommon\xa0and seen in about 3% of cases. These include\xa0encephalitis,\xa0meningitis, peripheral neuritis, aphasisa and cerebral vein thrombosis.\nStool & Urine culture may reveal Salmonella after 2 weeks of illness (not on 4th to 6th day).\n\nTwo important manifestation of typhoid fever in adults which are uncommon in children include\xa0:\n\nStepladder pattern of fever characteristic in adults is not seen in children.\xa0In children the onset is generally sudden with rapid elevation of temperature associated with headache and vomiting.\nRelative Bradycardia seen in adults is not always present in children.\xa0Pulse rate may rise proprotionately to the height of temperature.', 'role': 'assistant'}]