This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: FMGE 2019, Subject name: Pathology
[{'content': 'Which of the following has Autosomal Recessive inheritance? \nSelect and explain. \nA. Hereditary spherocytosis, B. Sickle cell anaemia, C. Osteogenesis imperfecta, D. VWD', 'role': 'user'}, {'content': "Answer: B \nExplanation: Sickle cell disease is a common hereditary hemoglobinopathy caused by point mutation resulting in replacement of Glutamic acid by Valine at 6th position of b-globin chain. Autosomal Recessive inheritance Autosomal Dominant (A Very DOMINANT Hereditary Family) Autosomal Recessive (ABCDEFGH'S) Achondroplasia/ADPKD Von Hippel Lindau disease Dystrophia myotonica Osteogenesis imperfecta Marfan Syndrome Intermittent porphyria NF 1(Von Recklinghausen disease) Achondroplasia NF 2 Tuberous Sclerosis Huntington Disease Familial hypercholesterolemia Albinism, Ataxia Telangiectasia, Alkaptonuria Beta thalassemia Cystic Fibrosis Dubin Johnson Emphysema (alpha 1 antitrypsin deficiency) Friedreich Ataxia Galactosemia Hemochromatosis Sickle cell anemia", 'role': 'assistant'}]