This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Obstructive Lung Disease, Subject name: Pathology
[{'content': 'Which of the following statement are true regarding asthma? \nSelect and explain. \nA. Occlusion of bronchi and bronchioles by mucus, B. Curschmann spirals, C. Charcot-Leyden crystals, D. All of the above', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Sputum or bronchoalveolar lavage specimen findings - Curschmann spirals (extrusion of mucus plugs from subepithelial mucous gland ducts or bronchioles). Numerous eosinophils and Charcot-Leyden crystals; the latter are composed of an eosinophil protein called galectin-10. Creola bodies The other characteristic histologic findings of asthma, collectively called "airway remodeling".', 'role': 'assistant'}]