This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'A patient, Tina was anesthetized with halothane and nitrous oxide and tubocurarine was used for skeletal muscle relaxation. She became hypertensive along with marked muscle rigidity and hyperthermia. Lab reports showed that she has developed hyperkalemia and acidosis. This complication was caused by: \nSelect and explain. \nA. Block of autonomic ganglia by tubocurarine, B. Pheochromocytoma, C. Activation of brain dopamine receptors by halothane, D. Excessive release of calcium from the sarcoplasmic reticulum', 'role': 'user'}, {'content': 'Answer: D \nExplanation: The symptoms of the patient (muscle rigidity, hypertension, hyperthermia, hyperkalemia and acidosis) suggest the diagnosis of malignant hyperthermia.\nHalothane can precipitate malignant hyperthermia in susceptible individuals. SCh increases this incidence.\nMalignant hyperthermia is due to excessive release of Ca2+ from the sarcoplasmic reticulum.\nDrug of choice for malignant hyperthermia is dantrolene that inhibits the release of Ca2+ (by blocking ryanodine re\xadceptors in the sarcoplasmic reticulum).', 'role': 'assistant'}]