This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hemolytic Anemias: Basic concepts and classification, Subject name: Pathology
[{'content': 'Cold agglutinin disease can be associated with all of the following, except: \nSelect and explain. \nA. Mycoplasma pneumoniae infection, B. Waldenstrom macroglobulinemia, C. SLE, D. EBV infection', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Warm Antibody Type hemolytic anemia is seen in SLE. Cold agglutinin disease (CAD)/Cold hemagglutinin disease (CHAD): Caused by IgM antibodies that bind to red cells avidly at low temperatures (0degC to 4degC) Cold agglutinin antibodies appear transiently following ceain infections, such as with Mycoplasma pneumoniae, Epstein-Barr virus, cytomegalovirus, influenza virus, and human immunodeficiency virus (HIV). Chronic cold agglutinin immunohemolytic anemia occurs in association with ceain B-cell neoplasms (Waldenstrom macroglobulinemia/lymphoplasmacytic lymphoma) or as an idiopathic condition.', 'role': 'assistant'}]