This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology and breast, Subject name: Surgery
[{'content': 'Tmreatment of hormone dependent fungating carcinoma of breasyt with secondaries in lung is \nSelect and explain. \nA. Simple mastectomy and oophoroctomy, B. Radical mastectomy and oophoroctomy, C. Adrenalectomy, D. Lumpectomy followed by castration', 'role': 'user'}, {'content': "Answer: A \nExplanation: Hormonal therapy in Carcinoma in breast Ovarian suppression or ablation Bilateral oophorectomy. Medically by LHRH agonist (Goserelin, leuprolide) SERM: Tamoxifen and Raloxifen Aromatase Inhibitors Non-steroidal : Letrozole & Anastrazole Steroidal : Exmestane Anti-Estrogens Fulvestrant Progestins Megesterol & Medroxyprogesterone acetate Ref: schwaz's principle of surgery 10th edition Pgno : 552-553", 'role': 'assistant'}]