This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunology, Subject name: Microbiology
[{'content': 'Wiskott Aldrich syndrome true is - \nSelect and explain. \nA. Raised IgE, B. Reduced IgM, C. Reduced IgA, D. CD4 and CD8 defect', 'role': 'user'}, {'content': 'Answer: B \nExplanation: In Wiskott-Aldrich syndrome serum IgM level is low but IgG & IgA levels are normal or elevated. Isohemagglutinins are absent in the serum. The humaral defect appears to be specific inabilityvto respond to polysaccharide antigens. Ref: Ananthanarayan & Panikers textbook of microbiology 9th edition pg.no. : 174', 'role': 'assistant'}]