This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of nucleic acids, Subject name: Biochemistry
[{'content': 'Coenzyme for methylmalonyl-CoA isomerase \nSelect and explain. \nA. Biotin, B. Cobalamine, C. Thiamine, D. Niacine', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Methylmalonyl-CoA mutase is a vitamin B12- dependent enzyme, and in deficiency methylmalonic acid is excreted in the urine (methylmalonic aciduria).Ref: Harpers Illustrated Biochemistry, 30th edition, page no: 187', 'role': 'assistant'}]