This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Primary Structural defect of an organ is termed: \nSelect and explain. \nA. Malformation, B. Disruption, C. Deformation, D. Association', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Primary structural defect of an organ is called as malformation. Primary malformations are caused by endogenous disturbances of the primordial tissues. Secondary malformations (disruptions) arise when organs develop abnormally from a normal primordium. Ref: Tanley L. Robbins, Ramzi S. Cotran, (2012) , Chapter 1, "Cell Injury", In the book, "Pocket Companion to Robbins and Cotran Pathologic Basis of Disease", 8th Edition, USA, Page 27 ; Robbin\'s Basic Pathology, 7th Edition, Pages 470-71', 'role': 'assistant'}]