This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Physiology
[{'content': 'Paneth cells in the Mucosa of the small intestine secrete \nSelect and explain. \nA. Lysozyme, B. Bioactive peptides and bioamines, C. Bicarbonate, D. Pepsin and Rennin', 'role': 'user'}, {'content': 'Answer: A \nExplanation: In the small intestine, Paneth cells residing at the bottom of the intestinal crypts are the key effectors of innate mucosal defense. -Paneth cells provide host defense against microbes in the small intestine. They are functionally similar to neutrophils. -Paneth cells secrete a number of antimicrobial molecules into the lumen of the crypt, thereby contributing to the maintenance of the gastrointestinal barrier. -Paneth cells are stimulated to secrete defensins, lysozyme & phospholipase A2. Ref: guyton and hall textbook of medical physiology 12 edition page number: 395,396,397', 'role': 'assistant'}]