This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Surgery
[{'content': 'E-cadherin is more often mutated in \nSelect and explain. \nA. Diffuse type of gastric cancer, B. Intestinal type of gastric cancer, C. Malignant ulcer of stomach, D. Erosive gastritis', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Hereditary diffuse gastric cancer is an inherited form of gastric cancer. Patients with this disorder, resulting from a gene mutation for the cell adhesion molecule E-cadherin, have an 80% lifetime incidence of developing gastric cancer.Ref: Sabiston 20th edition Pg: 1215', 'role': 'assistant'}]