This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney disorders, Subject name: Pathology
[{'content': 'All are true about nephronophthisis except: \nSelect and explain. \nA. Interstitial fibrosis, B. Coical tubular hyperophy, C. Cysts in the medulla, D. 20% cases are non-familial', 'role': 'user'}, {'content': 'Answer: B \nExplanation: 2 types of cystic disease affecting the renal medulla are : 1. Medullary sponge kidney Relatively common Usually innocuous condition Associated with nephrolithiasis 2.Nephronophthisis- Medullary cystic disease complex Associated with renal dysfunction. Cause of chronic kidney disease that usually begins in childhood. Coical tubulointerstitial damage and not hyperophy occurs in nephronophthisis.', 'role': 'assistant'}]