This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cholesterol and Lipoproteins, Subject name: Biochemistry
[{'content': 'Familial hypercholesterolemia is characterized by- \nSelect and explain. \nA. Increased LDL, B. Decreased lipoprotein lipase, C. Increased VLDL, D. All of the above', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Increased LDL Type IType IIaType IIbType IIIType IVType VProblemo Decreased lipoprotein lipase or Apo C-IIo LDL receptor deficiencyo |LDL receptor, increased Apo B-100o Defect in Apo-Eo Increased VLDL production and decreased elimination (Due to apo V deficiency)o Same as in type IV, but more severeLipoproteino Elevated chylomicrons (also VLDL some times)o |LDLo |VLDLo |LDLo Increased chylomicron remnants and IDLo |VLDLo |VLDL and chylomicronCholesterol|||||||||N|||Triglyceride||||N|||||||||NomenclatureFamilial lipoprotein lipase deficiencyo Familial hyper choleserolemiao Familial combined hyperlipidemiao Familial dys- beta lip oprei- nemiao Familial hypertriglyceridemiao Endogenous hypertrigly- cedemia", 'role': 'assistant'}]