This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Central Nervous system, Subject name: Pharmacology
[{'content': 'Which of the following agents do not act GABAA Cl- channel complex receptors? \nSelect and explain. \nA. Zopiclone, B. Benzodiazepines, C. Thiopentone, D. Promethazine', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Zopiclone (non benzodiazepine hypnotics ),benzodiazepine ,thiopentone(barbiturates) all act on GABA-Cl channel ,whereas promethazin is a antihistamine drug that acts on histaminergic receptors which causes high sedation. Ref: KD Tripathio 8th ed.', 'role': 'assistant'}]