This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'In which of the following enzyme does selenium act as a cofactor? \nSelect and explain. \nA. Glutathione peroxidase, B. Cytochrome oxidase, C. Cytochrome reductase, D. Xanthine oxidase', 'role': 'user'}, {'content': "Answer: A \nExplanation: Glutathione peroxidase contains selenium as a prosthetic group. In erythrocytes and other tissues, it catalyses the destruction of hydrogen peroxide and lipid peroxidase, protecting membrane lipids and hemoglobin against oxidation. Must know: Some other Co-factors that have been asked: Cofactor for carbonic anhydrase: Zn Cofactor for tyrosinase: Cu Cofactor for cytochrome oxidase Cu Cofactor for xanthine oxidase: Mo Cofactor for transamination reaction: Pyridoxine Cofactor for superoxide dismutase: Mn Ref: Bender D.A., Mayes P.A. (2011). Chapter 21. The Pentose Phosphate Pathway & Other Pathways of Hexose Metabolism. In D.A. Bender, K.M. Botham, P.A. Weil, P.J. Kennelly, R.K. Murray, V.W. Rodwell (Eds), Harper's Illustrated Biochemistry, 29e.", 'role': 'assistant'}]