This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
[{'content': "Gaucher's disease is inherited as? \nSelect and explain. \nA. Autosomal recessive, B. Autosomal dominant, C. X-linked recessive, D. X-linked dominant", 'role': 'user'}, {'content': 'Answer: A \nExplanation: Gaucher disease results from mutation in the gene that encodes glucocerebrosidase. There are three autosomal recessive variants of Gaucher disease resulting from distinct allelic mutations. Common to all is variably deficient activity of a glucocerebrosidase that normally cleaves the glucose residue from ceramide. This deficit leads to an accumulation of glucocerebroside, an intermediate in glycolipid metabolism, in the mononuclear phagocytic cells and their transformation into so-called Gaucher cells. (Robbins Basic Pathology,9th edition,pg no. 231)', 'role': 'assistant'}]