This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'The most important cytokine for the synthesis and deposition of connective tissue proteins is \nSelect and explain. \nA. PDGF, B. FGF-2, C. TGF-β, D. MMP', 'role': 'user'}, {'content': 'Answer: C \nExplanation: The laying down of connective tissue occurs in two steps:\xa0\n\nMigration and proliferation of fibroblasts into the site of injury.\nDeposition of ECM proteins produced by these cells.\xa0\n\nThese processes are orchestrated by locally produced cytokines and growth factors, including PDGF, FGF-2\xa0and TGF-β.\nTGF-β is the most important cytokine for the synthesis and deposition of connective tissue proteins.', 'role': 'assistant'}]