This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Pituitary-Hypothalmic System and Thyroid, Subject name: Pharmacology
[{'content': 'All of the following statements are true regarding carbimazole as compared to propylthiouracil except? \nSelect and explain. \nA. Carbimazole cross placenta less than propylthiouracil, B. Carbimazole is more potent than propylthiouracil, C. Carbimazole can be used as single daily dose whereas propylthiouracil needs to given thrice a day, D. Carbimazole does not inhibit peripheral conversion of T4 to T3', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Propylthiouracil has less transfer across placenta, so is preferred in first trimester of pregnancy. Propey Carbimazole PTU Potency Plasma half life Frequency of dosing Plasma protein binding Transfer across placenta Peripheral conversion Hepatotoxicity High More Once a day High High No effect Absent Low Less Thrice a day Low Low Inhibits Present', 'role': 'assistant'}]