This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Central Nervous system, Subject name: Pharmacology
[{'content': 'All of the following can be used to treat heroin dependence except \nSelect and explain. \nA. Disulfiram, B. Buprenorphine, C. Clonidine, D. Lofexidine', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Disulfiram is given for alcohol withdrawal. Buprenorphine is used as a maintaining drug in opioid addicts as it has a lesser degree of tolerance and dependence liability. Clonidine and lofexidine are alpha 2 agonists used to depress autonomic withdrawal symptoms like nausea, vomiting, anxiety and diarrhoea. Ref: KD Tripathi 8th ed.', 'role': 'assistant'}]