This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': 'All of the following are seen in Systemic Juvenile Arthritis, except – \nSelect and explain. \nA. Rheumatoid Factor + ve, B. Hepatosplenomegaly, C. High fever with rash, D. Elevated E.S.R.', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Systemic JRA\n\nIllness begins as intermittent fever rising upto 39° or (may precede joint involvement by several weeks and even upto 6 months)\nThere is a characteristic cavenescent maculopapular rash with central clearing\nLymphadenopathy and Splenomegaly may be present\nPericarditis and Interstitial lung disease may be present\nInvestigations show :\n\n\nImmoderate neutrophilic leucocytosis\nElevated ESR\xa0\xa0\xa0\nRF -ve\xa0\nANA can be demonstrated\xa0\n\nRemember\n\nEye manifestation (Iridocyclitis) can occur in both pauciarticular and polyarticular JRA and absent in systemic JRA\nANA can be present in all forms of JRA.\nRheumatoid factor & Rheumatoid Nodule are (+ve) only in some cases of polyarticular form.\nRashes, Splenomegaly and lymphadenopathy are present in system JRA.', 'role': 'assistant'}]