This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Psoriasis, Subject name: Dental
[{'content': 'A diagnosed case of psoriasis, taking MTX since last 15 yrs presents with jaundice and abnormal LFT. So, what will be the course of management: \nSelect and explain. \nA. Stop Mtx, sta dapsone, B. Mtx + cyclosporine, C. Stop Mtx, sta steroids, D. Stop Mtx, sta cyclosporine', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Methotrexate is hepatotoxic drug- Therefore, abnormal liver function test & jaundice (in history)- Next step- stop Mtx- Therefore, B is ruled out 3 systemic drugs used in psoriasis1. Mtx (Teratogenic, hepatotoxic)2. Cyclosporine (nephrotoxic)-3H( HTN, Hyperiglyceridemia , Hyperichosis)3. Acitretin- teratogenic, dyslipidemia. In psoriasis systemic steroids are C/I Dapsone have no role.', 'role': 'assistant'}]