This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Penicillin & Cephalosporin, Subject name: Pharmacology
[{'content': 'Carboxypenicillins true is all except - \nSelect and explain. \nA. Nephrotoxic, B. Sensitive to penicillinase, C. Effective against pseudomonas, D. Platelet aggregation affected', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' l.e., Nephrotoxic Carboxvpeniciilins - Carbenicillin:o It is active against pseudomonas and indole positive proteus.o Klebsiella and gram positive cocci are unaffected by ito It is neither penicillinase resistant nor acid resistant,o It is inactive orally and is rapily excreted in urine in 1 hr.o At high doses it can cause bleeding by interfering with platelet function due to perturbation of agonists receptors on platelet surface.# Carbenicillin indanyl is an orally active ester of carbenicillin, used for treatment of UTI caused by pseudomonas and proteus.", 'role': 'assistant'}]