This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'In glycolysis, the first committed step is catalysed by \nSelect and explain. \nA. 2, 3 DPG, B. Glucokinase, C. Hexokinase, D. Phosphofructokinase', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Phosphofructokinase catalyzes the committed step of glycolysis, meaning that once fructose 1, 6 - bisphosphate is formed it must go for the glycolytic pathway only.', 'role': 'assistant'}]