This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Toll like receptors, recognize bacterial products and stimulates immune response by, \nSelect and explain. \nA. Perforin and granzyme mediated apoptosis, B. Transcriptions of nuclear factor mediated by NFKP which recruits cytokines, C. FADD ligand apoptosis, D. Cyclin', 'role': 'user'}, {'content': 'Answer: B \nExplanation: The Toll-like receptors are membrane proteins that recognize a variety of microbe-derived molecules and\xa0stimulate innate immune responses against the microbes.\nThe Toll-like receptors are expressed on many different cell types that participate in innate immune responses\xa0including macrophages, dendritic cells, neutrophils, NK cells, mucosal epithelial cells and endothelial cells.\nSignalling by Toll like receptors results in the activation of transcription factors. notably NF-K0 and AP-L\nThe genes that are expressed in response to TLR signalling encode proteins important in many different\xa0components of innate immune response.\nThese include\nInflammatory\xa0cytokines (TNF, IL-1, IL-2)\nEndothelial adhesion molecules (E-selection) and\nProteins involved in microbial killing mechanisms.', 'role': 'assistant'}]