This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'Which is the most common congenital abnormality in a baby of a diabetic woman? \nSelect and explain. \nA. Ventricular septal defect, B. Anencephaly, C. Meningomyelocele, D. Sacral agenesis', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans: A Ventricular septal defectExplanation:(Ref. Nelson 20/e p898)Most common congenital abnormality in a baby of diabetic women is ventricular septa! defect.Congenital anomalies are increased threefold in infants of diabetic mothers.Most common anomalies:Cardiac malformations (ventricular or atrial septal defect, transposition of the great vessels, truncus aeriosus, double-outlet right ventricle, tricuspid atresia, coarciation of the aoa).Lumbosacral agenesis.Additional anomalies:Neural tube defects, hydronephrosis, renal agenesis and dysplasia, duodenal or anorectal atresia, situs in versus, double ureter, and holoprosencephaly.These infants may also demonstrate abdominal distention caused by a transient delay in development of the left side of the colon, the small left colon syndrome.', 'role': 'assistant'}]