This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Blood Physiology, Subject name: Physiology
[{'content': 'Which of the following changes occurs in RBCs of stored blood? \nSelect and explain. \nA. Increase in Na+ & K+ content, B. Decrease in Na+ & K+ content, C. Increase in Na+ & decrease in K+ content, D. Increased activity of Na+ - K+ ATPase.', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Changes in red cells during storage: Changes occur due to decreased metabolism.They are increase in their Na+ & decrease in K+ concentration due to reduced Na+-K+ pump activity, this results in a net increase in total base and water content of the cells that swell and become more spherocytic. The ATP content decreases and inorganic phosphate content increases.', 'role': 'assistant'}]