This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Oxidation of Fatty acids: Ketogenesis, Subject name: Biochemistry
[{'content': 'Ketone bodies are used by all except - \nSelect and explain. \nA. Brain, B. Heart muscles, C. Skeletal muscles, D. Hepatocytes', 'role': 'user'}, {'content': "Answer: D \nExplanation: Ans. is 'd' i.e., Hepatocytes o Ketone bodies are synthesized by liver and are utilized by extrahepatic tissues like heart, muscles, renal cortex and brain (in starvation). o Liver cannot utilize ketone bodies because it lacks enzyme succinyl-CoA-acetoacetate CoA transferase, which is required for the activation of ketone bodies, o The first reaction in use of ketone bodies is activation of acetoacetate. o Liver lacks the enzyme CoA transferase; hence cannot utilize ketone bodies. RBCs can't use fatty acids because they don't have mitochondria", 'role': 'assistant'}]