This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.V.S., Subject name: Pediatrics
[{'content': 'Which one is the best prognostic factor for ALL? \nSelect and explain. \nA. Hyperploidy, B. Orgnomegaly, C. TLC more than 50,000/mL, D. Response to treatment', 'role': 'user'}, {'content': "Answer: D \nExplanation: d. Response to treatment(Ref: Nelson's 20/e p 2437, Ghai 8/e p 599)Discussing options one by one:a. HyperploidyIntermediate prognosis; can be considered goodb. OrganomegalyL. Node, liver, spleen enlargement, Testicular enlargement - poor prognosisc. TLC >50,000/mLPoor prognosis; TLC <10,000/mL has good prognosisd. Response to treatmentEarly response to treatment is a good prognostic factor for ALL", 'role': 'assistant'}]