This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T., Subject name: Physiology
[{'content': 'Hepcidin acts on which receptor to inhibit the iron absorption? \nSelect and explain. \nA. DMT-1, B. Ferroportin, C. Hephaestin, D. Transferrin', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans. (b) FerroportinRef: Ganongs Review of Medical Physiology 25th Ed; Page No- 486* Maximum iron absorption occurs in duodenum.* Hepcidin is produced by liver. It represses the basolateral transport of iron into the blood.* Generally, transport of dietary iron into the enterocytes through divalent Metal Transporter-1 (DMT-1); some iron stored in ferritin; then excess iron transported out the enterocytes through basolateral named ferroportion 1.* Hepcidin level is regulated by HFF gene* Hepcidin is a crucial molecule in iron metabolism, linking body stores with intestinal iron absorption.* Mutation of HFF gene -Hemochromatosis', 'role': 'assistant'}]