This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Transplantation, Subject name: Surgery
[{'content': 'What is the primary toxicity of doxorubicin (Adriamycin)? \nSelect and explain. \nA. Cardiomyopathy, B. Pulmonary fibrosis, C. Peripheral neuropathy, D. Uric acid nephropathy', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Doxorubicin, an antibiotic derived from Streptomyces species, has activity against sarcomas and carcinomas of the breast, liver, bladder, prostate, head and neck, esophagus, and lung. Its major side effect is production of a dilated cardiomyopathy. Patients receiving this agent should have echocardiography before and after treatment in order to monitor potential cardiac toxicity.', 'role': 'assistant'}]