This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'About biotransformation not true ? \nSelect and explain. \nA. Active metabolite generation, B. Polar to less polar, C. Less polar to more polar, D. Generate active drug from prodrug', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., Polar to less polar", 'role': 'assistant'}]