This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Local anesthetics act by blocking \nSelect and explain. \nA. Na+ channels from outer side, B. K+ channels from outer side, C. Na+ channels from inner side, D. K+ channels from inner side', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Local anesthetics are weak bases that peneterate cell membrane in unionized form and within the cell membrane in ionized form they block voltage gated Na+ Channels.', 'role': 'assistant'}]