This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Not a characteristic feature of granuloma- \nSelect and explain. \nA. PMN’s with fibrinoid necrosis with cellular infiltrates, B. Epitheloid cell, C. Chronic inflammatory infiltrate, D. Giant cell', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Polymorphonuclear leucocytes or neutrophils have a major role in the acute inflammatory response. They are\xa0typically seen in acute inflammation.\nWhile granuloma formation is seen during the chronic inflammatory response.\nThe cells predominating during chronic inflammatory response are lymphocytes, plasma cells, monocytes etc.\xa0PMN’s or neutrophils are typically absent during chronic inflammation.\nGranuloma\nIt is an area of granulomatous inflammation.\nIt consists of i\n\nActivated macrophages* i.e. epitheloid cells\nCells surrounding activated macrophages, these are :\n\n\nMonocytes*\nLymphocytes* &\nPlasma cells*\n\n\nLanghans’ type giant cell* =>\n\nIt is a typical feature of epitheloid cell granuloma.\nIt is derived from the fusion of macrophages and characterized by 10-50 nuclei* around the periphery* of\xa0the cell.', 'role': 'assistant'}]