This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Breast Cancer - Prognosis and Follow-Up, Subject name: Surgery
[{'content': 'Most common site of metastasis for breast carcinoma is? \nSelect and explain. \nA. Lung, B. Liver, C. Brain, D. Bone', 'role': 'user'}, {'content': "Answer: D \nExplanation: ANSWER: (D) BoneREF: Bailey & Love 25th edition page 839, Schwartz's Principles of Surgery 9th edition chapter 17 Vertebra is the most common site of metastatic breast carcinoma. In order of frequency the lumbar vertebrae, femur, thoracic vertebrae, rib and skull are affected and these deposits are generally osteolytic.Metastases may also commonly occur in the liver, lungs and brain and, occasionally, the adrenal glands and ovaries", 'role': 'assistant'}]