This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'Mucus plugs containing epithelial cell aggregations arranged as whorls of shed epithelium in the airway mucus plugs seen in bronchial asthma is known as: \nSelect and explain. \nA. CharcotLeyden crystals, B. Curshmann spirals, C. Creola bodies, D. None of above', 'role': 'user'}, {'content': 'Answer: B \nExplanation: (Refer: Robbins Pathologic Basis of Disease, 8thedition, pg no: 691)\nHistopathology of bronchial asthma\n\nThe mucus plugs contain whorls of shed epithelium, spiral shaped mucus plugs called Curshmannspirals\nNumerous eosinophils.\nCharcot-Leyden crystals - collections of crystalloid made upof an eosinophil lysophospholipase binding protein calledGalectin-10.\nOverall thickening of airway wall.\nSub-basement membrane fibrosis (due to deposition oftype I and III collagen beneath the classic basementmembrane composed of type IV collagen and laminin).\nIncreased vascularity.\nIncrease in size of the submucosal glands; and\nMucous metaplasia of airway epithelial cells.\nHypertrophy and/or hyperplasia of the bronchial wall muscle.', 'role': 'assistant'}]