This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Majority of patients with HNPCC have mutations in ? \nSelect and explain. \nA. MSH I, B. MSH 2, C. MSH3, D. MSH4', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., MSH 2 Hereditary Nonpolyposis colorectal cancer (HNPCC) is caused by inherited mutations in genes that encode proteins responsible for the detection, excision, and repair of errors that occur during DNA replication.", 'role': 'assistant'}]