This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Apparent volume of distribution of a drug exceeds total body fluid volume, if a drug is - \nSelect and explain. \nA. Sequestrated in body tissues, B. Slowly eliminated from body, C. Poorly soluble in plasma, D. Poorly bound to plasma protein', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Sequestrated in body tissues o Drug may have volume of distribution for in excess of total body water if it is sequestered in other tissues because most of the drug is present in tissues and plasma concentration is low.", 'role': 'assistant'}]