This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hypolipidemic, Subject name: Pharmacology
[{'content': 'Statins inhibit which of the following enzyme - \nSelect and explain. \nA. HMG CoA reductase, B. HMG CoA synthetase, C. HMG CoA oxidase, D. Acetyl CoA synthetase', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., HMG CoA reductase * Statins (Lovastatin) competitively inhibit the conversion of HMG-CoA to mevalonate (rate limiting step in cholesterol synthesis) by inhibiting the enzyme HMG-CoA reductase.", 'role': 'assistant'}]