This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': 'Right Sided Isomerism is associated with: \nSelect and explain. \nA. Asplenia, B. One spleen, C. Two spleens, D. Polysplenia', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Cardiosplenic syndrome or Heterotaxy Syndrome \n\nNormal arrangement of organs and vessels within the body is called \'Sims solitus Complete reversal of organs and vessels within the body is called "situs invertus". Incomplete reversal/Random reversal of body organs is called "Situs ambiguous".\nHeterotaxy refers to the variation in the normal arrangement of organs and vessels within the body.\nVisceral heterotaxy (Situs ambiguous) is primarily classified on the bases of the position of spleen which is embryologically destined to be a left sided organ. Other normal assymetrical viscera are placed more or less sym\xadmetrically.\nSitus ambiguous or situs indeterminus is generally expressed in two major forms based on the position of spleen and whether the body resembles the normal right side or normal left side of the body.\n\n(i) Right isomerism (Asplenia)\n\nThe spleen is typically absent and hence either side of midline resembles right side.\nTherefore, it is also called bilateral right sidedness.\nIt is usually associated with severe complex cardiac abnormalities and has poor prognosis.\n\n(ii) Left isomerism (Polysplenia)\n\nThere are multiple small spleens placed on either side of midline, therefore, either side of the midline resembles the left (splenic) side.\nThus, it is also called bilateral left sideness.\nIt is associated with less severe cardiac abnormalities and has relatively better prognosis.', 'role': 'assistant'}]