This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': "Which of the following liver enzymes is predominantly mitochondrial \nSelect and explain. \nA. SGOT (AST), B. SGPT (ALT), C. GGT, D. 5' Nucleotidase", 'role': 'user'}, {'content': "Answer: A \nExplanation: Liver enzymes location \n\nEctoenzymes (Plasma membrane-bound) :- 5' nucleotidase (also called nucleotide phosphatase, NTP), Gamma-glutamyl transferase (gamma-glutamyl transpeptidase : GGT), alkaline phosphatase (ALP).\nMitochondrial:- Glutamate dehydrogenase (GDH), Aspartate aminotransferase (AST) or SGOT mitochondrial isoenzyme.\nCytosolic:- Lactate dehydrogenase (LDH), Alanine transaminase (ALT) or SGPT, SGOT (AST) cytosolic isoenzyme.\n\nNote:- In liver, the predominant isoenzyme of SGOT (AST) is mitochondrial.", 'role': 'assistant'}]