This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'What enzyme is inhibited by etoposide ? \nSelect and explain. \nA. Topoisomerase I, B. Topoismerase II, C. Dihydrofolate reductase, D. Dihydro orotate oxidase', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., Topoisomerase(Ref: KDT 7h/e p. 8661)EtoposideSemisynthetic derivative of podophyllotoxin, a plant glycoside'Not a mitotic inhibitor, but arrests cells in the G2 phase and causes DNA breaks by affecting DNA topoisomerase-2 function.", 'role': 'assistant'}]