This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'A 50–year old man has a history of frequent episodes of renal colic with high calcium renal stones. The most useful diuretic in the treatment of recurrent calcium stones is : \nSelect and explain. \nA. Furosemide, B. Spironolactone, C. Hydrochlorothiazide, D. Acetazolamide', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Thiazides cause hypercalcemia by decreasing the renal excretion of Ca2+. These are useful in a patient having hypercalciuria.\nIn such a patient, thiazides decrease the excretion of Ca2+ in the kidney and thus reduces the chances of stone formation.', 'role': 'assistant'}]