This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy, Subject name: Pharmacology
[{'content': 'What is the primary toxicity of busulfan \nSelect and explain. \nA. Lung fibrosis, B. Severe myeloidsupression, C. Cystitis, D. Hyperuricaemia', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Busulfan It is highly specific for myeloid elements( doses myelosupression occurs); granulocyte precursors being the most sensitive, followed by those of platelets and RBC. It produces little effect on lymphoid tissue and g.i.t. Side effects:- Hyperuricaemia is common; pulmonary fibrosis and skin pigmentation are the specific adverse effects. Sterility also occurs. Uses It is the drug of choice for chronic myeloid leukaemia. Ref:-kd tripathi; pg num:-861', 'role': 'assistant'}]