This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Moderate to high titres of anti-DNA and anti-Smith antibodies are almost pathognomonic of: \nSelect and explain. \nA. SLE, B. EM, C. Lichen planus, D. All of the above', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Laboratory Findings\nAntinuclear antibodies are frequently found in patients with SLE and can be used to indicate a\xa0systemic involvement, but patients with other rheumatologic diseases, such as Sjögren’s syndrome\xa0and rheumatoid arthritis, may be positive as well. Moderate to high titers of anti-DNA and anti-Smith\xa0antibodies are almost pathognomonic of SLE.', 'role': 'assistant'}]