This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'A 55-ycar-old woman presents with progressively\n\ndeepening jaundicc, uncontrollable pruritus, pain\n\nin the abdomen (right upper quadrant) and yellow\n\ncoloured urine. Investigations revealed - \nSelect and explain. \nA. Viral hepatitis, B. Cirrhosis of liver, C. Hepatocellular carcinoma, D. Carcinoma of head of the pancreas', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Around 60% of tumours arising from head of pancreas and involvement of common bile duct result in the development of obstructive jaundice, often with severe pruritis. Advanced stage present with central abdominal pain, weight loss, pain radiates from upper abdomen from back.', 'role': 'assistant'}]