This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Blood, Subject name: Pathology
[{'content': 'In AML, diagnosis of blasts cells is \nSelect and explain. \nA. 10% of myeloid blasts, B. 15% of myeloid blasts, C. 20% of myeloid blasts, D. 10% of myeloid blasts and 15% promyelocytes', 'role': 'user'}, {'content': 'Answer: C \nExplanation: C. i.e. (20% of myloid blasts) (462 - Basic pathology) (418 Harsh Mohan 5th)ACUTE MYELOGENOUS LEUKEMIA* As per WHO classification of leukemias, these criteria have been revised upwards to 20% blasts in the marrow for labeling and treating a case as AML (418 - Harsh Mohan 5th)* By definition, in AML myeloid blasts or promyelocytes make up more than 20% of bone marrow cellularity (462- Basic pathology 8th)* **DIC is seen in M3 type of AML* ** Auer rods, red -staining rod like structures present in the myeloblasts or more differentiated cells (Diagnostic clue)* Abnormal PML/RARA fusion proteins* Autoimmune haemolytic anemia is seen in CLL*** Chloroma is greenish in appearance due to the presence of myeloperoxidase seen in AML**** In AML, Chromosomal anomaly is - 8: 21 *** All - trans- retinoic acid is used in treatment for Acute- Promyelocytic Leukemia (PML)**', 'role': 'assistant'}]