This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Single Gene Disorders, Subject name: Pathology
[{'content': 'All of the following are seen in RASopathies except:- \nSelect and explain. \nA. Hair abnormalities, B. Craniofacial abnormalities, C. Keratosis pilaris, D. Desquamation of skin', 'role': 'user'}, {'content': 'Answer: D \nExplanation: RAS opathies:- Group of medical genetic syndrome caused by germ line mutation in genes that encode components or regulator of RAS or MAP kinase pathway: Clinical features:- Distinct Facial features Developmental delays Cardiac defect Growth delays Neurological issues GI difficulties Examples Noonan Syndrome Neurofibromatosis Type I Costello syndrome Cardia- facio cutaneous syndrome. Legius syndrome =Skin desquamation is not seen in RAS Opathies.', 'role': 'assistant'}]