This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
[{'content': "All of the following is true about leber's hereditary optic neuropathy except \nSelect and explain. \nA. Male predominance, B. X-linked recessive trait, C. Profound vision loss, D. Cardiac preexcitation syndrome", 'role': 'user'}, {'content': "Answer: B \nExplanation: X-linked recessive trait Leber hereditary optic neuropathy is transmitted in a pattern of maternal inheritance. The defect is in the Mitochondrial DNA Leber's hereditary optic neuropathy Remember: * Mitochondrial DNA inheritance * Male predominance * Visual loss profound & permanent * Rarely spontaneous recovery may occur * Characteristic fundus picture: Triad of - Microangiopathic telangiectasias - Pseudoedema of disc - Vascular touosity * Onset is sudden, mono ocular, painless vision loss.", 'role': 'assistant'}]