This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Orthopaedics
[{'content': 'Increased alkaline phosphate in seen in -a) Multiple myelomab) Primary hyperparathyroidismc) Chronic renal failured) Osteoporosis \nSelect and explain. \nA. a, B. c, C. bc, D. ad', 'role': 'user'}, {'content': "Answer: C \nExplanation: Whenever the activity of osteoblasts increase, serum alkaline phosphatase is raised. Therefore, serum alkaline phosphatase acts as an index of osteoblastic activity.\nThe conditions in which osteoblastic activity is increased and hence the alkaline phosphatase in increased are : -\n\n\nRickets/osteomalacia\xa0\xa0\xa0\xa0\xa0\xa0 \xa0\nPrimary hyperparathyroidism\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\nRenal osteodystrophy (secondary hyperparathyroidism)\nChronic renal failure and secondary hyperparathyroidism\nPaget's disease (osteitis deformans)\nOsteoblastic secondaries", 'role': 'assistant'}]