This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Which of the following estimates blood creatinine level most accurately - \nSelect and explain. \nA. Jaffe method, B. Kinetic jaffe method, C. Technicon method, D. Enzyme assay', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Among the given options, the enzyme assay is the most accurate.\nMethods to measure serum creatine to assess GFR are:-\n\ni)\xa0Gas chromatography-isotope dilution mass spectroscopy (GC-IDMS):-\xa0It is the most accurate and method of choice.\nii) High-performance liquid chromatography (HPLC).\n(iii)\xa0Enzymatic creatinine method (enzyme assay).\n(iv)Alkaline picrate methods:- Jaffe method\n\nAccuracy in decreasing order is GC-IDMS > HPLC > Enzyme assay > Alkaline picrate (Jaffe) method.', 'role': 'assistant'}]