This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Lipids, Subject name: Biochemistry
[{'content': 'In a child with cerebrohepatorenal syndrome and with hypotonia and hepatomegaly, the probable biochemical defect is accumulation of: \nSelect and explain. \nA. Pyruvate, B. Short chain fatty acids, C. Very long chain fatty acids, D. Acetyl CoA', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans. C. Very long chain fatty acids (VCLFAs)Cerebrohepatorenal syndrome is also known as Zellweger syndrome, a rare congenital disorder. It is caused due to the reduction or absence of the peroxisomes in the cell. Peroxisomes are the site of oxidation of VCLFAs.Deficiency of peroxisomes leads to increased concentration of VLCFAs.', 'role': 'assistant'}]