This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Other topics and Adverse effects, Subject name: Anatomy
[{'content': "True statement about cyclooxygenase-2 is \nSelect and explain. \nA. It Is not inhibited by indomethacin, B. It I'd inducible, C. It generate cytoprotective prostaglandins in gastric mucosa, D. It is found only in fatal tissues", 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ref-KDT 6/e p185 COX-1 is a house-keeping enzvme that is responsible for the generation of gastroprotective PGs. COX-2 is an inducible enzyme whose production is markedly increased at inflammatory sites. Indomethacin is a non-selective inhibitor of both isoforms of COX.', 'role': 'assistant'}]