This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Abortion, Subject name: Gynaecology & Obstetrics
[{'content': "A woman with H/o recurrent abortions presents with isolated increase in APTT. Most likely cause is: \nSelect and explain. \nA. Lupus anticoagulant, B. Factor VII, C. Von Willebrand's disease, D. Hemophilia A", 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. is a, i.e. Lupus anticoagulantRef. Dutta Obs. 6/e, p 343; Fernando Arias 3/e, p 327; Leon Speroff 7/e, p 1082Isolated increase in APTT is suggestive of lupus anticoagulant.', 'role': 'assistant'}]