This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Iron deficiency anemia, Subject name: Pathology
[{'content': 'A 25 year old women presents with recurrent abdominal pain and anaemia. Peripheral blood smear shows basophilic stippling of the RBCs. What is the most likely diagnosis? \nSelect and explain. \nA. Coeliac disease, B. Hookworm disease, C. Sickle cell disease, D. Lead poisoning', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Basophilic stippling a.k.a Punctate basophilia These inclusions are precipitated ribosomal RNA. Stippling is observed in cases of: Hemoglobinopathies Dys-erythropoietic states like: Lead poisoning megaloblastic anemias thalassemias sideroblastic anemias Alcoholism Pyriinidine-5- nucleotidase deficiency RBC inclusions: Inclusion Content Howell- Jolly body DNA Basophilic stippling RNA Pappenheimer body Iron Heinz body Denatured Hb Cabot ring Mitotic spindle remnant', 'role': 'assistant'}]