This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Histamine, 5-HT and PGs, Subject name: Pharmacology
[{'content': 'All of the following statements are TRUE about second generation antihistaminic agents EXCEPT: \nSelect and explain. \nA. These do not impair psychomotor performance, B. These possess high anti-motion sickness activity, C. These lack anticholinergic actions, D. These may possess additional antiallergic mechanisms', 'role': 'user'}, {'content': 'Answer: B \nExplanation: 1st generation 2nd generation Cross BBB, cause sedation Donot cross BBB, no sedation Ach blockade, anticholinergic side effect occur No Ach blockade Useful for - Motion sickness - Drug induced parkinsonism - Muscular dystonias - Allergy Useful only for allergy Promethazine, diphenhydramine, diphenhydrinate, phenramine, Terfenadine, fexofenadine, loratidine', 'role': 'assistant'}]