This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
[{'content': 'Necrotizing aerioritis with fibrionoid necrosis is- \nSelect and explain. \nA. Immediate hypersensitivity, B. Cell mediated* unity, C. Antigen-antibody complex mediated, D. Cytotoxic cell mediated', 'role': 'user'}, {'content': "Answer: C \nExplanation: Type III hypersensitivity occurs when there is accumulation of immune complexes (antigen-antibody complexes) that have not been adequately cleared by innate immune cells, giving rise to an inflammatory response and attraction of leukocytes. Such reactions progressing to the point of disease produce immune complex diseases.Disease Target antigen Main effects Systemic lupus erythematosus Nuclear antigens Nephritis Skin lesions Ahritis Rheumatoid Ahritis Antibody complexes: specifically IgM to IgG Ahritis Post-streptococcal glomerulonephritis Streptococcal cell wall antigens Nephritis Polyaeritis nodosa Hepatitis B virus surface antigen Systemic vasculitis Reactive ahritis Several bacterial antigens Acute ahritis Serum sickness Various Ahritis Vasculitis Nephritis Ahus reaction Various Cutaneous vasculitis Farmer's Lung Inhaled antigens (often mould or hay dust) Alveolar inflammation Henoch-Schonlein purpura Unknown, likely respiratory pathogen Purpura Glomerulonephritis Ref Robbins 9/e p125", 'role': 'assistant'}]