This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Which antibodies in mother with SLE is responsible for congenital heart disease in child- \nSelect and explain. \nA. Anti-histone, B. Anti-Ro & Anti-LA, C. Anti ds DNA, D. Anti-centromere', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Most sensitive\xa0→ Antinuclear antibody (ANA)\nMost specific\xa0→ Anti-double stranded antibody and the antibody against Smith (Sm)\nAssociated with neonatal\xa0lupus and congenital heart block\xa0→ Anti Ro, Anti LA antibody\nAssociated with lupus\xa0psychosis\xa0→ Anti P antibody', 'role': 'assistant'}]