This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'Which one of the following is least likely to occur in late extra articular sero-positive rheumatoid arthritis - \nSelect and explain. \nA. Neutropenia, B. Dry eye, C. Leg ulcers, D. Hepatitis', 'role': 'user'}, {'content': 'Answer: D \nExplanation: None', 'role': 'assistant'}]