This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'All is true about Giant cell arteritis except - \nSelect and explain. \nA. Most commonly involved artery is abdominal aorta, B. Involves large to small sized arteries, C. Granulomatous inflammation, D. Segmental nature of the involvement', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Giant cell arteritis (Temporal arteritis)\n\nIt is the most common form of systemic vasculitis in adults, is an acute and chronic, often granulomatous, inflammation of arteries of large to small size.\nIt affects principally the arteries in the head-especially the temporal arteries—but also the vertebral and\xa0ophthalmic arteries and the aorta, where it may cause a thoracic aortic aneurysm\n\nGiant cell arteritis or temporal arteritis\n\nIt is the most common form of systemic vasculitis in adults.\nIt is an acute and chronic; often granulomatous inflammation\xa0of arteries of large to small size,\nGiant cell arteritis\xa0affects principally the arteries in the head, especially the temporal arteries which is\xa0the extracranial branch of the carotid\xa0artery,\nVertebral and ophthalmic arteries may also be involved.\nA segment of the affected artery develops nodular thickening with narrowing of the lumen.\nThere is granulomatous inflammation in the vessel wall with a foreign body and Langhans type\xa0multinucleated giant cells and fragmentation of internal elastic lamina.\n\nPresentation of Giant cell arteritis\xa0\no Constitutional symptoms\n\nMost common nonspecific symptoms\nInclude malaise, fatigue, anorexia and weight loss.\nThese symptoms are due to the generalized involvement of the body and are not related to any organ\xa0involvement,\n\no A headache\n\nIt is the most common vasculitis related symptom.\nMost commonly over temporal region.\n\no Jaw claudication\n\nIt is the most specific symptom of GCA.\nIt is manifested as pain in masseter when eating food that requires vigorous chewing because\xa0oxygen demand of the masseter exceeds the supply provided by narrowed and inflamed arteries.\n\no Visual symptoms\n\nDiplopia and visual loss.\nOphthalmic artery involvement can lead to sudden blindness which is the most feared\xa0complication of GCA.\n\no Polymyalgia rheumatica\n\nAching and stiffness of the shoulder, neck and lip girdle area,\n\no Arthritis\no Raised ESR\no Normocytic-Normochromic anaemia', 'role': 'assistant'}]