This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Physiology
[{'content': 'All are actions of coisol on the skin and connective tissue except \nSelect and explain. \nA. Antiproliferative for fibroblasts, B. Antiproliferative for keratinocytes, C. Loss of collagen, D. Hyperpigmentation', 'role': 'user'}, {'content': 'Answer: D \nExplanation: It is antiproliferative for fibroblasts and keratinocytes. Glucocoicoids in excess inhibit fibroblasts, lead to loss of collagen and connective tissue, and thus result in thinning of the skin, easy bruising, stria formation, and poor wound healing. Hyperpigmentation is a direct effect of ACTH on melanocoin 1 receptors.', 'role': 'assistant'}]