This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Liver, Subject name: Surgery
[{'content': 'Which of the following statement is true regarding pyogenic liver abscess? \nSelect and explain. \nA. Diagnosis can be confirmed by serological test, B. Radiographic features are diagnostic, C. Usually a large and single abscess is seen in cases of direct spread, D. Systemic manifestations are uncommon', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans. (c) Usually a large and single abscess is seen in cases of direct spread* Pyogenic Liver abscess - Serology is not useful* Radiographic Features are not diagnostic.* Systemic manifestations are common.* MC type is Solitary and Large abscess due to Direct spread from Cholecystitis, Empyema Chest and Perinephric Abscess or Subdiaphragmatic collection.', 'role': 'assistant'}]