This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy, Subject name: Pharmacology
[{'content': 'A patient suffering from AIDS is on Zidovudine, Lamivudine, Indinavir therapy, He develops pulmonary tuberculosis for which treatment is staed. Which of the following should be avoided in him \nSelect and explain. \nA. INH, B. Ethambutol, C. Pyrazinamide, D. Rifampicin', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Refer KDT 6/e p 741 *Rifamipicin is a powerful enzyme inducer. It increases the metabolism of protease inhibitors and thus decreases the efficacy of anti retroviral therapy *another drug, rifabutin is devoid of these interactions and is the preferred agent for treatment of mycobacterial infections in patients', 'role': 'assistant'}]