This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Neuromuscular Blocker, Subject name: Anaesthesia
[{'content': 'Extent of nicotinic receptor blockade required for neuromuscular transmission failure due to non-depolarizing neuromuscular blockers:- \nSelect and explain. \nA. <5%, B. About 20%, C. About 30%, D. >80% - 90%', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Non depolarising neuromuscular blocker are competitive blockers and when more than 80 -90 % receptor is blocked then only neuromuscular transmission fails. Characteristic of NDNB 1. Decreased twitch response to a simple stimulus. 2. Fade on tetanic stimulus 3. Train of four response is seen 4. TOF ratio <1 5. Post tetanic potentiation 6. Potentiation of other nondepolarising drugs Antagonism by anticholinesterase', 'role': 'assistant'}]