This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Renal Tumors, Subject name: Surgery
[{'content': 'Most important prognostic indicator for Renal cell carcinoma: \nSelect and explain. \nA. Nuclear grade, B. Histological type, C. Size, D. Pathological staging', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans is \'d\' i.e. Pathological staging Ref: Campbell-Walsh Urology 9/e Section XII- Neoplasms of the upper urinary tract, Chapter 47; 8/e p1604 "Pathologic stage has proved to be the single most important prognostic factor for RCC. Various studies have shown a strong correlation between Robson\'s pathologic stage and 5-year survival rates for RCC. Similar but more discerning results have been reported for tumors staged with the TNM classification system, confirming that the extent of locoregional or systemic disease at diagnosis is the primary determinant of outcome for this disease."- Campbell- Walsh Urology 9/e Section XII- Neoplasms of the upper urinary tract, Chapter 47; 8/e p1604', 'role': 'assistant'}]