This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Which of the following medications is contraindicated in patients with allergy to sulphonamides? \nSelect and explain. \nA. Levobunolol, B. Bimatoprost, C. Brinzolamide, D. Brimonidine', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Acetazolamide, Dorzolamide and Brinzolamide are sulfonamide derivatives which act by inhibiting carbonic anhydrase (carbonic anhydrase inhibitor). Being sulphonamide derivatives they are contraindicated in patients with allergy to sulphonamides. Ref: Essentials of Pharmacology By K D Tripathi, 5th Edition, Pages 188, 553; Medicinal Chemistry By Sriram, Page 227.', 'role': 'assistant'}]