This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Maternal and child care, Subject name: Social & Preventive Medicine
[{'content': 'Most common cause of vaccine failure \nSelect and explain. \nA. Improper storage, B. Improper administration, C. Improper manufacturing, D. Maternally derived antibodies', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Primary Vaccine failure Failure to serological respond to Vaccine. To young age where maternal antibodies interfere (MC cause) Vaccine production problems Cold chain failure. Inappropriate administration technique Immunodeficiency Poor heath. Secondary vaccination failure "waning immunity" where there is loss of vaccine induced protection in an individual who had previously seroconveed to vaccination Causes are not well understood Ref: Microbiology and Infectious Disease by Hagan & Brunner, 8th edition Pgno : 510', 'role': 'assistant'}]