This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Eosinophilia in necrosed tissue is due to ? \nSelect and explain. \nA. Coagulation of proteins, B. Denaturation of enzymes, C. Denaturation of protein, D. Mitochondrial damage', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Necrotic cells show increased eosinophilia in hematoxylin and eosin (H & E) stains. It is mainly due to these 2 Factors Loss of cytoplasmic RNA (or ribonucleoprotein/RNP) which binds the blue dye, hematoxylin. Denatured cytoplasmic proteins which bind the red dye, eosin.', 'role': 'assistant'}]