This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Delayed prolonged bleeding is caused by - \nSelect and explain. \nA. Histamine, B. Leukocyte dependent injury, C. IL-1, D. Direct injury to endothelial cells', 'role': 'user'}, {'content': "Answer: D \nExplanation: Ans. is `d' i.e., Direct injury to endothelial cellso Delayed prolonged leakage is caused either by the direct effect of injurious agent or by cytokine mediated endothelial retraction.", 'role': 'assistant'}]