This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Anatomy
[{'content': 'Hereditary chronic pancreatitis is caused by mutation of \nSelect and explain. \nA. Cationic trypsinogen or PRSS1, B. CFTR, C. PTSI, D. SPINK1', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Hereditary pancreatitis Autosomal dominant disease Due to a missence mutation on cationic trypsinogen, or PRSS1(Protease, serine 1) results in premature, intrapancreatic activation of trypsinogen The incidence is equal in both sexes Ref: Sabiston 20th edition Pgno :1532', 'role': 'assistant'}]