This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': 'A 7 – year old boy with left renal mass had bone pain and was detected to have bone metastatic deposits. The most likely renal tumor is : \nSelect and explain. \nA. Favorable histology Wilms tumor, B. Renal cell carcinoma, C. Clear cell sarcoma, D. Rhabdoid tumor', 'role': 'user'}, {'content': "Answer: C \nExplanation: Clear cell carcinoma is a histological subtype of wilm’s tumor which frequently metastasize to bone (In conventional wilms's tumor bone metastasis is rare).\nHistology of wilms tumor \n\nWilms tumor is a complex mixed embryonal neoplasm, comprises three elements : -\n\n\nBlastenia.\nMesenchyme.\nEpithelium.\n\n\nOn the basis of outcome Wilms tumor has been classified into two histological subtypes.\n\nFavorable histology :\n\nIt is the conventional form and carries good prognosis.\nComprises blastoma, epithelial and stromal elements.\nDevoid of anaplasia or ectopia.\nBrain and bone metastasis is rare.\nMetastasis may occur to lung.\n\nUnfavorable histology :\n\n\nCharacterized by marked enlargement of nuclei, hyperchromatism, and multipolar mitotic figures.\nAnaplasia is present.\nClear cell sarcoma is a subtype of the unfavorable form and usually metastasizes to bone.\n\nNote :\n\nRhabdoid tumor, which may metastatize to the brain, is no longer classified as a subtype of wilms tumor.", 'role': 'assistant'}]