This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy, Subject name: Pharmacology
[{'content': 'Radiation protector drug in clinical use among the following is \nSelect and explain. \nA. Amifostine, B. Cisplatin, C. Mesna, D. Tirapazamine', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Amifostine is used therapeutically to reduce the incidence of neutropenia-related fever and infection induced by DNA-binding chemotherapeutic agents including alkylating agents and platinum-containing agents . It is also used to decrease the cumulative nephrotoxicity associated with platinum-containing agents. Amifostine is also indicated to reduce the incidence of xerostomia in patients undergoing radiotherapy for head and neck cancerReference: Perez and Brady&;s textbook of radiation oncology; 6th edition', 'role': 'assistant'}]