This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cytotoxic Anticancer Drugs, Subject name: Pharmacology
[{'content': 'Bleomycin toxicity affects which organ predominantly? \nSelect and explain. \nA. Bone marrow, B. Lungs, C. Liver, D. RBC', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Bleomycin is metabolized by bleomycin hydrolase. This enzyme is deficient in skin and lungs. Therefore, the major adverse effects of bleomycin are: Flagellated pigmentation of skin Pulmonary fibrosis', 'role': 'assistant'}]