This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Proteins and Amino Acids, Subject name: Biochemistry
[{'content': 'DNA repair defect is seen in: \nSelect and explain. \nA. Xeroderma pigmentosum, B. Li-fraumani syndrome, C. Retinoblastoma, D. None', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. (a) Xeroderma pigmentosumRef: Harper's Biochemistry, 30th ed. pg. 389-90, 28th ed.pg. 330-32* Xeroderma pigmentosum is an autosomal recessive genetic disease which arises due to defect in DNA repair particularly of thymidine dimers.Examples of Conditions Arising due to DNA Repair Defects:* Xeroderma pigmentosa* Ataxia telangiectasia* Fanconi's syndrome* Bloom syndrome* HNPCC", 'role': 'assistant'}]