This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'Which of the following liver disorders is a compli¬cation associated with oral contraceptives? \nSelect and explain. \nA. Drug-induced hepatitis with fatty change, B. Cholangiocarcinoma, C. Cavernous hemangiomas, D. Intrahepatic cholestasis', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Oral contraceptives produce an intrahepatic cholestasis that is unpredictable (not related to the dose). The incidence of liver cell adenomas is also increased as a result of oral contraceptive use. These vascular tumors have a tendency to rupture during pregnancy, particu\xadlarly those in a subcapsular location.\nA purported increase in the incidence of focal nodu\xadlar hyperplasia (FNH) is associated with oral contra\xadceptive use. Grossly, FNH is characterized by a poorly encapsulated nodule that has a lighter color than the surrounding hepatic parenchyma. On cut section, a centrally located stellate scar radiates out to the periph\xadery of the lesion. Microscopically, the hepatocytes be\xadtween the scar tissue are normal.\nA slightly increased risk for hepatocellular carci\xadnoma is another effect of birth control pills on the liver.\nOral contraceptives are not associated with drug-induced hepatitis with fatty change, cholangiocarci\xadnoma, cavernous hemangiomas, or fulminant hepatic failure.', 'role': 'assistant'}]