This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of nucleic acids, Subject name: Biochemistry
[{'content': 'Protein that initiates synthesis of RNA primers \nSelect and explain. \nA. SSBs, B. DNA Ligase, C. DNA Primase, D. Topoisomerases', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Classes of Proteins Involved in Replication Protein Function DNA polymerases Deoxynucleotide polymerization Helicases ATP -driven processive unwinding of DNA Topoisomerases Relieve torsional strain that results from helicase-induced unwinding DNA primase Initiates synthesis of RNA primers Single-strand binding proteins (SSBs) Prevent premature reannealing of dsDNA DNA ligase Seals the single strand nick between the nascent chain and Okazaki fragments on lagging strand Harper30e pg: 378', 'role': 'assistant'}]