This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: miscellaneous, Subject name: Pathology
[{'content': 'In familial Mediterranean fever, the following protein undergoes mutation- \nSelect and explain. \nA. Pyrin, B. Perforin, C. Atrial natriuretic factor, D. Immuunoglobulin light chain', 'role': 'user'}, {'content': 'Answer: A \nExplanation: The gene for familial Mediterranean fever has been cloned, and its product is called pyrin (for its relation to fever). Although its exact function is not known, it has been suggested that pyrin is responsible for regulating acute inflammation, presumably by inhibiting the function of neutrophils. Ref: Pathologic Basis Of Disease 7th ed - Robbins, Coltran (Elsevier, 2005) pg no:85', 'role': 'assistant'}]