This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
[{'content': 'BRCA 1 gene is located on chromosome \nSelect and explain. \nA. 17p21, B. 17q21, C. 13p21, D. 13q21', 'role': 'user'}, {'content': 'Answer: B \nExplanation: A BRCA mutation is a mutation in either of the BRCA1 and BRCA2 genes, which are tumour suppressor genes. ... Women with harmful mutations in either BRCA1 or BRCA2 have a risk of breast cancer that is about five times the normal risk, and a risk of ovarian cancer that is about ten to thiy times normal.', 'role': 'assistant'}]