This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cellular Pathology, Subject name: Pathology
[{'content': 'Earliest change in cell death is? \nSelect and explain. \nA. Karyolysis, B. Loss of plasma membrane, C. Cell swelling, D. Karyorrhexis', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans. (c) Cell swelling(Ref: Robbins 9th/pg 46; 8th/pg 12)Earliest change in any form of cell injury is cellular swelling due to accumulation of water intracellularly.', 'role': 'assistant'}]