This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
[{'content': 'Delayed prolonged bleeding is caused by \nSelect and explain. \nA. Histamine, B. Leukocyte dependent injury, C. IL-I, D. Direct injury to endothelial cells', 'role': 'user'}, {'content': 'Answer: D \nExplanation: EndotheliumDirect injury to endothelial cells causes delayed prolonged bleeding because, endothelial cells are central regulators of hemostasis, the balance between the anti-and prothrombotic activities of endothelium determines whether thrombus formation, propagation or dissolution occurs.Robbins basic pathology 9th edition page no 79', 'role': 'assistant'}]