This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'The central cellular players in the repair process are? \nSelect and explain. \nA. Platelets, B. Macrophages, C. Neutrophils, D. Fibroblasts', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Inflammatory cells eliminate the offending agents, such as microbes that may have entered through the wound, and clear the debris. Macrophages are the central cellular players in the repair process—M1 macrophages clear microbes and necrotic tissue and promote inflammation in a positive feedback loop, and M2 macrophages produce growth factors that stimulate the\xa0 proliferation of many cell types in the next stage of repair. As the injurious agents and necrotic cells are cleared, the inflammation resolves.\n\xa0Macrophages are critical for orchestrating the repair process, by eliminating\xa0 offending\xa0 agents\xa0 and\xa0 producing\xa0 cytokines\xa0 and growth factors that stimulate the proliferation of the cell types involved in repair.\nRobin’s Textbook of pathology 10th ed\xa0 Page 89', 'role': 'assistant'}]