This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Inflammatory Bowel Disease, Subject name: Medicine
[{'content': 'A highly sensitive and specific marker for detecting intestinal inflammation in ulcerative colitis is: \nSelect and explain. \nA. CRP, B. Fecal lactoferrin, C. Fecal calprotectin, D. Leukocytosis', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Active disease can be associated with a rise in acute phase reactants , platelet count, erythrocyte sedimentation rate (ESR), and a decrease in hemoglobin. Fecal lactoferrin is a highly sensitive and specific marker for detecting intestinal inflammation. Fecal calprotectin levels correlate well with histologic inflammation, predict relapses, and detect pouchitis. Leukocytosis may be present but is not a specific indicator of disease activity. Proctitis or proctosigmoiditis rarely causes a rise in CRP.', 'role': 'assistant'}]