This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
[{'content': 'Destruction of zona glomerulosa will deplete: \nSelect and explain. \nA. Aldosterone, B. Cortisol, C. Testosterone, D. Catecholamines', 'role': 'user'}, {'content': 'Answer: A \nExplanation: The zona glomerulosa, a thin layer of cells that lies just\xa0 underneath\xa0 the\xa0 capsule, constitutes about 15 percent of the adrenal cortex. These cells are the only ones in the adrenal gland capable of secreting significant amounts of aldosterone because they contain the enzyme aldosterone synthase, which is necessary for synthesis of aldosterone. The secretion of these cells is controlled mainly by the extracellular fluid concentrations of angiotensin II and potassium, both of which stimulate aldosterone secretion.', 'role': 'assistant'}]