This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Childhood tumors, Subject name: Pediatrics
[{'content': 'True about neuroblastoma \nSelect and explain. \nA. Tumor of automatic nervous system, B. Metastasis rarely present, C. Earliest detected in late childhood, D. Most common site is Adrenal medulla', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Neuroblastoma is a malignant tumor of the autonomic nervous system derived from the neural crest.It is a disease of early childhood with 90% of patients presenting before 5 years of age & almost 50% of patients presenting within the first 2 years.The most common site is adrenal medulla(30%).Metastasis present in 60-70% children,are usually to the skeleton(facial bones,skull),bone marrow and lymph nodes. Reference:Essential pediatrics-Ghai,8th edition,page no:616,617.', 'role': 'assistant'}]