This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hematology, Subject name: Pharmacology
[{'content': 'CAPLACIZUMAB is used for treatment of? \nSelect and explain. \nA. Acquired Thrombotic Thrombocytopenic Purpura (aTTP), B. Plaque Psoriasis, C. Breast cancer, D. Bladder cancer', 'role': 'user'}, {'content': 'Answer: A \nExplanation: CAPLACIZUMAB: a. It is a Von - Willebrand factor (vWF) directed antibody fragment b. Target the A1 - domain of vWF, and inhibits the interaction between vWF and platelets, thereby reducing both vWF - mediated platelet adhesion and platelet consumption. c. Used for treatment of acquired Thrombotic Thrombocytopenic Purpura (aTTP)', 'role': 'assistant'}]