This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology and breast, Subject name: Surgery
[{'content': 'Malti a 45 year old female patient with a family history of breast carcinoma, showed diffuse microcalcification on mammography, Intraductal carcinoma is insitu was seen on biopsy. Most appropriate management is: \nSelect and explain. \nA. Quandrandectomy, B. Radical mastectomy, C. Simple mastectomy, D. Chemotherapy', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Breast carrcinoma Treatment: A. Early Invasive Breast carcinoma (Stage I, IIA, IIB): Mastectomy+ Axillary LN status assessement BCT+ Axillary LN status assessment+ If sentinel LN cannot be identified or found to harbour metastasis disease, axillary LN dissection (Level I+II) should be done. Simple or Total mastectomy: Removal of breast tisuue, nippple-areola complex, & skin. Ref: Sabiston 20th edition Pgno: 853', 'role': 'assistant'}]