This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': "Which one of the following diseases characteristically causes a fatty change in liver? \nSelect and explain. \nA. Hepatitis B virus infection, B. Wilson's disease, C. Hepatitis C virus infection, D. Chronic alcoholism", 'role': 'user'}, {'content': "Answer: D \nExplanation: Alcoholic liver disease (ALIT) is the most frequent secondary fatty liver disease. The secondary fatty liver can also occur in chronic Viral hepatitis C (HCV), chronic viral hepatitis, chronic autoimmune hepatitis (AIH), and Wilson's disease'\xa0\nThus although fatty liver may be seen secondary to all options mentioned in the question chronic alcoholism being the most common cause is the single best answer here.\nFollowing information have been added in 8th/e of Robbins\xa0\xa0Non alcoholic fatty liver disease (NAFLD)\nIt has become the most common cause of chronic liver disease in united states NAFLD includes:\n\nSimple hepatic steatosis → Stable conditions\nSteatosis with inflammation\xa0→\xa0Stable conditions\nNon-alcoholic steatohepatitis (NASH) → Can progress to cirrhosis\n\nNAFLD is the most common cause of cryptogenic cirrhosis (cirrhosis of unknown origin).", 'role': 'assistant'}]