This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'At mu receptor, buphrenorphine is ? \nSelect and explain. \nA. Paial agonist, B. Paial antagonist, C. Complete agonist, D. Complete antagonist', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Paial agonist o Buprenorphine is paial agonist at p. receptor and antagonist at Kappa receptor. Buprenorphine (paial agonist lc antagonist) o It is 25 times more potent than morphine. It substitutes for morphine at low levels of dependence but precipitates withdrawl in highly dependent suspect ---> Paial agonistic action at receptors. o Naloxone only paially reverse buprenorphine effects and does not precipitate its withdrawl because of more tight binding of buprenorphine to opioid receptors. It can be used for the management of opioid withdrawl, alternative to methadone.", 'role': 'assistant'}]