This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cellular Pathology, Subject name: Pathology
[{'content': 'Sirtuin is associated with? \nSelect and explain. \nA. Cancer, B. Diabetes, C. Ageing, D. All of the above', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans. (d) All of the above(Ref: Robbins 9th/pg 67,68)SirutuinsFamily of NAD-dependent protein deacetylases.Sirtuin-6 Q promotes the expression of genes whose products increase longevity.Since these protiens increase longevity, activate DNA repair enzymes so prevent against cancerSirtuins also increase insulin sensitivity and glucose metabolism, and may be targets for the treatment of diabetes.', 'role': 'assistant'}]