This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'CIN III progresses to carcinoma in how many % of cases: \nSelect and explain. \nA. 25%, B. 5%, C. 0%, D. 60%', 'role': 'user'}, {'content': 'Answer: A \nExplanation: CIN: Cervical intraepithelial neoplasia-part or whole of thickness of cervical squamous epithelium is replaced by cell of varying degress of atypia\nCIN: Microinvasive carcinoma- invasive carcinoma cervix (over several years)\n\nMostly asymptomatic, diagnosed by routine screening done yearly after a women become sexually active. If 3 consecutive smears normal in a low risk woman do once in 3 years\nCIN I-Abnormality in lower 1/3rd of epithelium\nCIN II-Abnormality in lower 2/3rd of epithelium\nCIN III-Abnormality in >2/3rd of epithelium\n\nHigh risk factor--\xad\n\nAge <18 yr at initiation of coitus\nMultiple sex partners, husband with multiple parteners\nHPV infection\nHigh oncogenic risk-type 16, 18, 31, 45, 56\nLow oncogenic risk-type 6, 11\nCMV, HSV II infection\nSmoking\nPoor socioeconomic status\nAneuploid lesion\nOral contraceptive use.', 'role': 'assistant'}]