This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Small intestine, Subject name: Surgery
[{'content': 'A newborn presented with bloated abdomen sholy after bih with passage of less meconium. A full thickness biopsy of the rectum was carried out. Which one of the following rectal biopsy findings is most likely to be present? \nSelect and explain. \nA. Fibrosis of submucosa, B. Hyalinization of the muscular coat, C. Thickened muscularis propria, D. Lack of ganglion cells', 'role': 'user'}, {'content': "Answer: D \nExplanation: Hirschsprung's disease:- Absence of ganglion cells- M/C pa - rectum > Sigmoid- Affected segment - Contracted / Narrowed - Longer & narrower the segment - More are S/S of Intestinal obstruction Dx -Full thickness Rectal biopsy", 'role': 'assistant'}]