This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'True statement about fexofenadine is : \nSelect and explain. \nA. It undergoes high first pass metabolism in liver, B. Terfenadine is an active metabolite of this drug, C. It does not block cardiac K+ channels, D. It has high affinity for central H1 receptors', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Fexofenadine is an active metabolite of terfenadine. It lacks K+ channel blocking property, therefore is devoid of arrhythmogenic potential. It is available as a separate second-generation H1 blocking agent.', 'role': 'assistant'}]