This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology metabolism, Subject name: Physiology
[{'content': 'Major thyroxine binding protein - \nSelect and explain. \nA. Albumin, B. Prealbumin, C. Globulin, D. Transferrin', 'role': 'user'}, {'content': "Answer: C \nExplanation: Ans. is 'c' i.e., Globulin o Most of the circulating thyToid, hormones are protein bound, leaving only 0.02% T, and about 0.2% T. unbound or free.o There are three hormone binding plasma proteins, i.e., thyroxine binding globulin (major thyroid hormone binding protein), thyroxine binding albumin and thyroxine binding prealbumin.o Thyroid binding globulin level is raised in pregnancy and by drugs estrogens, methadone, heroin, tranquilizers, clofibrate.o TBG decreases by glucocorticoid, androgen, danazol, asparginase (cancer chemotherapy) and nephrotic syndrome.", 'role': 'assistant'}]