This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anaesthesia, Subject name: Pharmacology
[{'content': 'All of the following are propeies of local anesthetics EXCEPT: \nSelect and explain. \nA. Blockade of voltage dependent Na+ channels, B. Preferential binding to resting channels, C. Slowing of axonal impulse conduction, D. Increase in the membrane refractory period', 'role': 'user'}, {'content': 'Answer: B \nExplanation: - Local anesthetic receptor is located within the channel in its intracellular half. - LA traverses the membrane in unionized form. - LAs act from within the neuron and are more active when the neuron is rapidly firing (i.e., Na+ channels are open). so it doesnot act in resting form.', 'role': 'assistant'}]