This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Skin Cancer, Subject name: Skin
[{'content': 'Rx for stage 1 mycosis fungoids - \nSelect and explain. \nA. PUVA, B. Biological response modifiers, C. Systemic chemotherapy, D. Extracorporial photopheresis', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., PUVA Treatment of cutaneous T-cell lymphomaStage 1A-IIA (Patch/Plaque)o No treatmento PUVA or UVB therapy for patches +/- INF alfao Topical corticosteroidso Local radiation therapy (single lesion) or total skin electron beam radiation (TSEB) (generalised plaues)o Topical mechlormethamineorcarmustineo Oral methotrexateStage 1IB (skin tumours)o PUVA-IFN alfao Oral retinoids + PUVA / IFN alfao TSEB & local radiationStage IIIo Topical mechlormethamine or carmustineo PUVA + IFN alfao Oral methotrexateo Systemic chemotherapyo TSEB & local radiationo Extracorporeal photopheresisStage IVo Oral methotrexateo Systemic chemotherapyo Oral bexaroteneo Biological response modifiers (denileukin or IL-12)o TSEB & local radiation", 'role': 'assistant'}]