This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Primary Open-Angle Glaucoma and Related Conditions, Subject name: Ophthalmology
[{'content': 'What is the mechanism of action of latanprost? \nSelect and explain. \nA. Decrease in aqueous secretion from ciliary eputhelium, B. Increased uveoscleral outflow, C. Opening of trabecular meshwork leading to increased outflow, D. Decreased vitreous volume', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., Increased uveoscleral outflow Mechanism of action of pharmacological agents in POAGAgentMechanism of actiono b-blocker (Timolol, Betaxolol, levobunolol, carteolol)o Prostaglandins (latanoprost, bimatoprost, travoprost)o Alpha agonists# Non-selective (Epinephrine, Dipivefrine)# Selective a-2 (Aproclonidine, Brimonidine)o Carbonic anhydrase inhibitors (Dorzolamide, Brinzolamide, Acetazolamide)o Cholinomimetics (Pilocarpine, physostigmine, carbachol, echothiphate)o Hyperosmotic agents (Mannitol, glycerol)o Decreased aqueous secretion from ciliary epitheliumo Increased uveoscleral aqueous outflowIncreased uveoscleral aqueous outflowDecreased aqueous secretiono Decreased aqueous secretion due to lack of HCO3-o Increased aqueous outflow due to opening of trabecular meshwork due to ciliary muscle contractiono Reduce vitreous volume and deepen anterior chamber", 'role': 'assistant'}]