This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Which statements are true about E. coli chromosomal DNA in relation with eukaryotic chromosomal DNA \nSelect and explain. \nA. Circular, B. Negatively supercoiled, C. Nucleoid present, D. All of these', 'role': 'user'}, {'content': 'Answer: D \nExplanation: E.coli (Bacteria) has single, closed, circular, ds DNA which is negatively supercoiled, present in nucleoid. There is no nucleolus in bacteria.', 'role': 'assistant'}]