This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'A patient presented with diminished vision and neuropsychiatric manifestations and with hepatic dysfunction.  His eyes on general examination and slit lamp examination appeared as shown in the Figure below.  What investigation you will do next? \nSelect and explain. \nA. Serum ceruloplasmin level, B. 24 hr Urine copper level, C. MRI brain, D. Haplotyping', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ref. API Textbook of Medicine. Pg. 870\n\xa0\nImage represents “Kayser-Fleischer” ring -\xa0\xa0KF ring is golden brown ring due to deposition of copper in Descement’s membrane of cornea.\n\xa0\nWilson’s Disease:\n\nRare autosomal recessive disease.\nCharacterized by abnormal copper metabolism\n\nSternlieb's criteria:\n\nPresence of KF rings\nDecreased serum ceruloplasmin (copper containing enzyme / ferroxidase) levels\nMeasuring hepatic copper levels in liver biopsy\n24-Hr urine copper excretion\n\n● Kayser Fleischer ring:\n\nExcess circulating copper deposits in descemet’s membrane.\nUsually golden brown located in peripheral cornea, beginning at schwalbe’s line upto 5 mm into cornea.\nDetected via Gonioscopy in earlier stage & seen by naked eyes in advanced stage.", 'role': 'assistant'}]