This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cytotoxic Anticancer Drugs, Subject name: Pharmacology
[{'content': 'Hand and foot syndrome is an adverse effect of: \nSelect and explain. \nA. 5-Fluorouracil, B. Bleomycin, C. Etoposide, D. Actinomycin D', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Capecitabine and 5-FU can cause hand and foot syndrome. Diarrhea is the most common adverse effect of 5-FU. 5-FU can also cause bone marrow suppression. Drugs commonly implicated are: Capecitabine 5-Fluorouracil Cytarabine Pemetrexed Doxorubicin', 'role': 'assistant'}]