This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Inflammation & Repair, Subject name: Pathology
[{'content': 'The principle cell in granuloma \nSelect and explain. \nA. Fibroblast, B. Epithelioid cell, C. Giant cell, D. Plasma cell', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans. (b) Epithelioid cell(Ref: Anderson 10th ed pg 583)Macrophages (also known as histiocytes) are the cells that define a granulomaThe macrophages in granulomas are often referred to as "epithelioid"Epithelioid macrophages differ from ordinary macrophages in that they have elongated nuclei that often resemble the sole of a slipper or shoe.These changes are thought to be a consequence of "activation" of the macrophage by the offending antigen.', 'role': 'assistant'}]