This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'A patient on chronic use of NSAIDs has developed peptic ulcer. DOC to treat the condition is: \nSelect and explain. \nA. Pirenzepine, B. Loxatidine, C. Misoprostol, D. Esomeprazole', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Proton pump inhibitors are the drugs of choice for peptic ulcer disease due to any aetiology. \nMisoprostol is the most specific\xa0drug for the treatment of PUD due to chronic NSAID use, because it is a PGE1 analogue.\nPUD = Peptic Ulcer Disease.', 'role': 'assistant'}]