This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'Contraindications to the use of combined oral contraceptives are all except \nSelect and explain. \nA. Migraines with focal neurological defecit, B. Coronary artery disease, C. Suspected Osteosarcoma, D. Diabetes with vascular involvement', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Contraindications to the Use of Combination Oral Contraceptives\xa0\n\nPregnancy\nUncontrolled hypertension.\nSmokers older than 35 years.\nDiabetes with vascular involvement.\nCerebrovascular or coronary artery disease.\nMigraines with associated focal neurologic deficits.\nThrombophlebitis or thromboembolic disorders.\nHistory of deep-vein thrombophlebitis or thrombotic disorders.\nThrombogenic heart arrhythmias or thrombogenic cardiac valvulopathies.\nUndiagnosed abnormal genital bleeding.\nKnown or suspected breast carcinoma.\nCholestatic jaundice of pregnancy or jaundice with pill use.\nHepatic adenomas or carcinomas or active liver disease with abnormal liver function.\nEndometrial cancer or other known or suspected estrogen-dependent neoplasia.', 'role': 'assistant'}]