This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
[{'content': 'Type-I hypersensitivity is mediated by which of the following immunoglobulins: \nSelect and explain. \nA. IgA, B. IgG, C. IgM, D. IgE', 'role': 'user'}, {'content': 'Answer: D \nExplanation: IgE', 'role': 'assistant'}]