This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Which anticancer drug prevents spindle formation? \nSelect and explain. \nA. Busulfan, B. Vinca alkaloids, C. 5 - FU, D. Methotrexate', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., Vinca alkaloids Taxanes (Paclitaxel and Docetaxel) enhances polymerization of tubulin (a mechanism opposite to that of vincaalkaloids) -the microtubules are stabilized and their depolymerization is prevented. Vinca alkaloids (vincristine, vinblastine)prevent polymerization and assembly of microtubules. Mitotic inhibitors Enhances polymerization Preventpolymerization Taxanes Vinca alkaloids", 'role': 'assistant'}]