This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Virology, Subject name: Microbiology
[{'content': 'True about prions is - \nSelect and explain. \nA. Encoded by viral genome, B. Associated with misfolding of protein, C. Non infectious, D. Immunogenic', 'role': 'user'}, {'content': 'Answer: B \nExplanation: prion is due to mis folding of ptotiens leads to proliferation of abnormal prion protein REF:ANATHANARAYANAN MICROBIOLOGY NINTH EDITION PAGE.557', 'role': 'assistant'}]