This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
[{'content': 'Which of these muscles undergoes wasting first in osteoahritis knee? \nSelect and explain. \nA. Quadriceps only, B. Hamstrings only, C. Both quadriceps and Hamstrings, D. Gastronemius', 'role': 'user'}, {'content': 'Answer: A \nExplanation: All periaicular muscles around the knee joint may undergo wasting in advanced osteohritis knee. However muscle atrophy paicularly involves the quadriceps which is the earliest muscle to undergo wasting. Ref: Turek s Ohopaedics 2nd Edition, Page 1368.', 'role': 'assistant'}]