This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology and breast, Subject name: Surgery
[{'content': 'Treatment of Hormone dependent fungating carcinoma of breast with secondaries in the lung in a female patient aged 30 years is \nSelect and explain. \nA. Simple mastectomy followed by oophorectomy, B. Radical mastectomy followed by oophorectomy, C. Adrenalectomy, D. Lumpectomy followed by castration', 'role': 'user'}, {'content': "Answer: A \nExplanation: Hormonal therapy in Carcinoma Breast Ovarian suppression or ablation Bilateral oophorectomy. Medically by LHRH agonist (Goserelin, leuprolide) SERM: Tamoxifen and Raloxifen Aromatase Inhibitors Non-steroidal : Letrozole & Anastrazole Steroidal : Exmestane Anti-Estrogens Fulvestrant Progestins Megesterol & Medroxyprogesterone acetate Ref: schwaz's principle of surgery 10th edition Pgno : 552-553", 'role': 'assistant'}]