This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Which of the following eicosanoids cause vasoconstriction as well as increase vascular permeability? \nSelect and explain. \nA. Prostacyclin, B. Thromboxane A2, C. PGE1, D. Leukotriene C4', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Principal Inflammatory Actions of Arachidonic Acid Metabolites (Eicosanoids) ACTION EICOSANOIDS Vasodilation PGI2 (prostacyclin), PGE1, PGE2, PGD2 Vasoconstriction Thromboxane A2, leukotrienes C4, D4, E4 Increased vascular permeability Leukotrienes C4, D4, E4 Ref: Robbins 8th edition Chapter 2.', 'role': 'assistant'}]