This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'Which of the following is associated with PAS positive macrophages? \nSelect and explain. \nA. Whipple disease, B. Abetalipoproteinemia, C. Crohns disease, D. Ulcerative colitis', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ref. Robbins Pathology. 9th edition. Page. 791\n\xa0\nWhipple disease:\n\nRare systemic infection due to\xa0Tropheryma whippelii, a gram positive intracellular actinomycete\nUsually affects proximal intestine, mesenteric lymph nodes\nAlso called intestinal lipodystrophy\n\n\xa0\nSymptoms:\n\nMalabsorption with diarrhea, weight loss, abdominal pain\nOccasionally polyarthritis, CNS complaints, lymphadenopathy, hyperpigmentation\nCardiac involvement less common\n\n\xa0\nMicroscopy\n\nDistended macrophages in lamina propria containing PAS+ (diastase resistant) granules and rod shaped bacilli by EM\nDilated lymphatics or fat vacuoles', 'role': 'assistant'}]