This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': "The most common coagulation disorders haemophilia A and Von Willebrand's disease are due to - \nSelect and explain. \nA. Factor IX deficiency, B. Vitamin K deficiency, C. Factor X deficiency, D. Factor VIII deficiency", 'role': 'user'}, {'content': "Answer: D \nExplanation: Hemophilia (Bleeder's disease or the disease of kings) is due to deficiency of Factory 8. Von Willebrand disease is due to an abnormality; either quantitative or qualitative, of the VWF, which is a large multimeric glycoprotein that functions as the carrier protein for factor 8. VWF also is required for normal platelet adhesion. It functions in both primary (involving platelet adhesion) and secondary (involving\xa0 factor VIII) hemostasis.", 'role': 'assistant'}]