This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Gilbe syndrome, true all except ? \nSelect and explain. \nA. Causes cirrhosis, B. Autosomal dominant, C. Normal liver function test, D. Normal histology', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Causes cirrhosis Gilbe's Syndrome: ? o It is an autosomal dominant condition. o It is characterized by unconjugated hyperbilirubinemia (normally the bilirubin is transpoed into liver cells by intracellular proteins. In the liver bilirubin is conjugated. This conjugation is brought about by ceain enzymes. In Gilbe's syndrome these enzymes are absent which cause unconjugated hyperbilirubinemia). The hyperbilirubinemia is usually precipitated by following conditions - Stress, Fatigue, Alcohol use, reduced calorie intake, intercurrent illness. The hepatic biochemical tests are normal except for elevated bilirubin level (serum bilirubin concentration are usually < 3mg/dl) Embryonal carcinoma The hepatic histology is normal There is no association with cirrhosis.", 'role': 'assistant'}]