This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Cephalosporin that does not require dose reduction in a patient with any degree of renal impairment is : \nSelect and explain. \nA. Cefuroxime, B. Cefoperazone, C. Ceftazidime, D. Cefotaxime', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ceftriaxone and cefoperazone are excreted mainly in the bile, therefore do not require dose reduction in any grade of renal failure.', 'role': 'assistant'}]