This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Arthritis, Subject name: Orthopaedics
[{'content': 'HLA-B27 is associated with: \nSelect and explain. \nA. Gouty arthritis, B. Rheumatoid arthritis, C. Ankylosing spondylitis, D. Systemic lupus erythematosis', 'role': 'user'}, {'content': "Answer: C \nExplanation: (Ankylosing spondylitis): Ref 59- A, 1937-HAnkylosing spondylitis: - There is a strong tendency to familial aggregation and association with the genetic marker HLA - B27* HLA -DR4 occurs in about 70% of people with Rheumatoid arthritis (51 -A)* HLA - B27 markers associated with - Reiter's syndrome, Acute anterior uveitis, Reactive arthritis, Psoriatic spondylitis* SLE is associated with HLA DR2 DR3", 'role': 'assistant'}]