This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: NEET Jan 2020, Subject name: Physiology
[{'content': 'Impaired function of Aquaporin results in \nSelect and explain. \nA. Nephrogenic DI, B. Liddle syndrome, C. Cystic fibrosis, D. Baer syndrome', 'role': 'user'}, {'content': 'Answer: A \nExplanation: ADH acts V2 receptors on DCT casuing facultative reabsorption of water by inseing Aquaporin -2 channels into apical (luminal side ). Nephrogenic DI-defect in aquaporins BATER SYNDROME - Autosomal recessive Defect in"Na-K-2Cl cotranspoer, Cl channel & ROMK"in loop of Henle LIDDLE SYNDROME - Gain of function of epithelial Na channel (ENaC) Cystic fibrosis - CH-7 defect in CFTR gene - causing defect in transmembrane chloride ion regulation.', 'role': 'assistant'}]