This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'A perimenopausal woman on Pap smear has repoed ASCUS (atypical squamous cell of unknown significance). Next line of management is: \nSelect and explain. \nA. Loop excision, B. Conization, C. Colposcopy, D. Hysterectomy', 'role': 'user'}, {'content': 'Answer: C \nExplanation: In Bethesda system, the most common cytological abnormality is atypical squamous cells (ASC). ASC is fuher divided into ASCUS (atypical squamous cell of unknown significance) and ASC-H (atypical squamous cells where HSIL cannot be ruled out). The risk of progression of ASCUS to CIN is 5%. These patients should be followed up with: 1. HPV DNA testing 2. Immediate colposcopy 3. Repeated cytology at 6-12 months Ref: GYANECOLOGICAL DIAGNOSIS ; Novak, 15th edition, page 587q', 'role': 'assistant'}]