This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'High hepatic first-pass metabolism is seen in all EXCEPT \nSelect and explain. \nA. Insulin, B. Propranolol, C. Lignocaine, D. Nitroglycerin', 'role': 'user'}, {'content': 'Answer: A \nExplanation: -\xa0Except for Insulin, all the three options undergo high first pass metabolism.\n-\xa0Drugs showing high first pass metabolism\n\n\xa0 \xa0Isoprenaline\n\xa0 \xa0Lidocaine\n\xa0 \xa0Hydrocortisone\n\xa0 \xa0Testosterone\n\xa0 \xa0Propranolol\n\xa0 \xa0Verapamil\n\xa0 \xa0Salbutamol\n\xa0 \xa0Morphine\n\xa0 \xa0Pethidine', 'role': 'assistant'}]