This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Blood, Subject name: Pathology
[{'content': 'Cryoprecipitate cannot be used in? \nSelect and explain. \nA. Von-Wilbrand diseas, B. Hemophilia A, C. Hemophilia B, D. DIC', 'role': 'user'}, {'content': "Answer: C \nExplanation: Ans. is 'c' i.e., Hemophilia B * Hemophilia B (Christmas disease) is due to deficiency of factor IX. Cryoprecipitate does not contain factor IX. Therefore cannot be used.* Fresh frozen plasma or recombinant factor IX is used for treatment.* Cryoprecipitate contains fibrinogen, factor VIIIc and vWF, and factor XIII. It is most commonly used in hypofibrinogenemia (e.g. in DIC).* It can also be used in hemophilia A and von-Willebrand disease (but recombinant factor and desmopressin are preferred in these conditions).", 'role': 'assistant'}]