This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Substance Related and Addictive Disorders, Subject name: Psychiatry
[{'content': 'Ekbom syndrome is:- \nSelect and explain. \nA. Narcolepsy, B. Restless leg syndrome, C. Pica, D. Delusion of nihilism', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Restless leg syndrome / Ekbom syndrome. Sensorimotor disorder, commonly seen in 5-15% of the population. Affects females and after 40 years. 4 salient diagnostic features being: Urge to move limbs, commonly associated with premonitory sensory discomfo Motor restlessness Relief by activity Evening/Night worsening Pathophysiological explanations or mechanisms attributed are: Dysregulation of dopamine transmission Intracellular iron dysregulation. This can be objectively substantiated by decreased CSF ferritin and prohepcidin (Intracellular regulatory protein for iron) levels.', 'role': 'assistant'}]