This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Impoant Genetic Syndromes, Subject name: Pediatrics
[{'content': "A 12-year-child, who has intellectual disability, is having large face, large jaw, large ear and macroorchidism. Diagnosis? \nSelect and explain. \nA. Mc Cune Albright syndrome, B. Down's syndrome, C. Cri-du chat syndrome, D. Fragile X syndrome", 'role': 'user'}, {'content': "Answer: D \nExplanation: Fragile X syndrome- CGG trinucleotide repeats. Intellectual disability, large face, large jaw, large ear and macro-orchidism. Cri-du chat syndrome- high pitched cry, microcephaly, intellectual disability, hypotonia Mc Cune Albright syndrome- cafe au lait pigmentation, fibrous dysplasia, endocrine dysfunction Down's syndrome- mongloid slant, epicanthal folds, depressed nasal bridge", 'role': 'assistant'}]