This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Disorder of Metabolism & Connective Tissue, Subject name: Medicine
[{'content': 'Which of the following statement is false about Hurler syndrome: \nSelect and explain. \nA. X linked, B. MR, C. Joint stiffness, D. Coarse facial features', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. (a) X linkedRef: Harrison's 17th ed. Ch.DisorderEnzymeDef:InheritanceNeurologicOphthalmo- logicHematologicUnique FeaturesHurler syndromea-L- IduronidaseARMental retardation +Corneal cloudingVacuolated lymphocytesCoarse facies, cardiovascular involvement, joint stiffness, wide spaced teethHunter syndromeIduronate sulfatase (ET)X-linkedMental retardation, less in mild formRetinal degeneration, no corneal cloudingGranulated lymphocytesCoarse facies, cardiovascular, joint stiffness, distinctive pebbly skin lesions* Both have hepatosplenomegaly and skeletal dysplasia* In Hurler syndrome, death usually occurs by 10 years because of respiratory infection and heart failure.", 'role': 'assistant'}]