This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T., Subject name: Pathology
[{'content': 'Histopathological finding of gluten hypersensitivity is? \nSelect and explain. \nA. Crypt hyperplasia, B. Increase in thickness of the mucosa, C. Distal intestine involvement, D. Villous hypertrophy', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Crypt hyperplasia Histopathological findings of gluten sensitivity enteropathy* Villous atrophy and Crypt hyperplasia with decrease in villus: crypt ratio.* Loss of microvilli brush border.* Inflammatory cells are present in lamina propria : plasma cells, macrophages, lymphocytes, eosinophils and mast cells.* One of the characteristic feature is that overall mucosal thickness remains same (as villous atrophy is compensated by crypt hyperplasia).* Mainly proximal intestine is involved.", 'role': 'assistant'}]