This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Potassium supplementation often is necessary for patients taking which drug? \nSelect and explain. \nA. Spironolactone, B. Triamterene, C. Furosemide, D. Amiloride', 'role': 'user'}, {'content': "Answer: C \nExplanation: Spironolactone is a competitive antagonist of aldosterone and therefore, may cause hyperkalemia if administered concomitantly with potassium supplements. Likewise, the potassium-sparing diuretics triamterene and amiloride cause potassium retention. Furosemide promotes renal potassium excretion and often requires concomitant supplemental potassium administration. Ref: Reilly R.F., Jackson E.K. (2011). Chapter 25. Regulation of Renal Function and Vascular Volume. In L.L. Brunton, B.A. Chabner, B.C. Knollmann (Eds),Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e.", 'role': 'assistant'}]