This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Pediatrics
[{'content': 'Celiac disease is children is most commonly associated with: \nSelect and explain. \nA. HLA-DQ2, B. HLA-DQ3, C. HLA-DQ8, D. Blood group B', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. A. HLA-DQ2* Celiac disease is an immune-mediated enteropathy that is triggered by ingestion of gluten in genetically susceptible individuals.* Three factors can activate the disease; Ingestion of gluten-containing products; Dysfunction of intestinal mucosal barrier; and Genetic predisposition (HLA DQ2 / DQ8).* About 95% of patients of celiac disease express HLA-DQ2, and the remaining patients are usually HLA-DQ8 positive.', 'role': 'assistant'}]