This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'Worst prognosis in renal cell carcinoma is assocaited with - \nSelect and explain. \nA. Haematuria, B. Size>5cm, C. Invasion of renal vein, D. Pulmonary secondaries', 'role': 'user'}, {'content': 'Answer: D \nExplanation: None', 'role': 'assistant'}]