This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Childhood Tumors, Subject name: Pediatrics
[{'content': 'Retinoblastoma gene is located on: \nSelect and explain. \nA. Chromosome 5, B. Chromosome 8, C. Chromosome 13, D. Chromosome 16', 'role': 'user'}, {'content': "Answer: C \nExplanation: c. Chromosome 13(Ref: Nelson's 20/e p 2476-2478, Ghai 8/e 614-615)Retinoblastoma (RB) geneIt is located on chr 13q14; its mutation or deletion is responsible for hereditary form of RetinoblastomaIt encodes the retinoblastoma protein, a tumor suppressor protein that controls cell-cycle phase transition and has roles in apoptosis and cell differentiation", 'role': 'assistant'}]