This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Urinary tract, Subject name: Anatomy
[{'content': 'In Wilms tumor the following leads to emergence of resistance to chromotherapy \nSelect and explain. \nA. Nehprogenic rests, B. Monoblastic morphology, C. Anpalsia, D. Capsular infiltration', 'role': 'user'}, {'content': 'Answer: C \nExplanation: 5 percnt of tumors have Anpalsia, defined as the presence of cells with large hyperchromatic pleomprphic nuclei and abnormal mitosis and the presrnc of anapladsia coreltes with p53 mutation', 'role': 'assistant'}]