This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Troponin-T is a marker of - \nSelect and explain. \nA. Renal diseases, B. Muscular dystrophy, C. Cirrhosis of liver, D. Myocardial infarction', 'role': 'user'}, {'content': 'Answer: D \nExplanation: MARKERS IN MYOCARDIAL INFARCTION\n\nMyoglobin\nEarliest marker to rise\nRises within 1 hour\nClears in 4-12 hours\nPoor specificity.\nCardiac-specific troponin T (cTnT) and troponin I (cTnI)\nNormally NOT detectable in healthy individuals without MI\nMost sensitive cardiac biomarker\nRise at 2 to 4 hours\nThe peak at 48 hours\nRemain elevated upto 7-10 days\nElevated in microinfarctions (NSTEMI), not in unstable angina.\nCreatine kinase (CK)\nCK rises within 4-8 hours\nReturns to normal in 48-72 hours\nNot specific, also rises in Muscle disease. Trauma. IM injections. Defibrillation\nCK MB isoenzyme is more cardiac specific\nCK MB also high in Myocarditis, Cardioversion. Cardiac surgery\nThe ratio of CK MB mass: CK activity > 2.5 suggestive of a cardiac cause.\nLactate dehydrogenase (LDH)\nLast marker to rise.\nLDH-1 is specific to cardiac tissue\nLDH-l/LDH-2 ratio is a good indicator of MI.\nAspartate aminotransferase - Rarely used clincially.', 'role': 'assistant'}]