This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Disorders of Adrenal Gland, Subject name: Medicine
[{'content': 'Inactivation of coisol into coisone occurs mainly in which organ? \nSelect and explain. \nA. Lungs, B. Liver, C. Adrenals, D. Kidney', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Coisol is inactivated to coisone by microsomal enzyme 11b-hydroxysteroid dehydrogenase type II This enzyme is mainly in the kidney. Other organs involved in this activity are colon, salivary glands and other target tissues.', 'role': 'assistant'}]