This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'A 10 year old female patient complains of tiredness and shortness of breath. Patient is a known case of beta-thalassemia. This disease is caused by faulty splicing of: \nSelect and explain. \nA. hnRNA, B. snRNA, C. scRNA, D. snoRNA', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Faulty splicing can cause diseases: Splicing of hnRNA has to\xa0be\xa0performed with\xa0precision to produce functional mRNA. Faulty splicing may result in diseases. A good example is one type of beta-thalassemia in\xa0 humans. This\xa0is\xa0due\xa0to\xa0a mutation that results in a nucleotide change at an exon-intron junction. The result is a\xa0diminished or\xa0lack of\xa0synthesis of\xa0p-chain of\xa0hemoglobin, and consequently the disease p-thalassemia.\nNote:\xa0\nscRNA - Small cytoplasmic RNA\nsnoRNA - Small nucleolar RNA\nsnRNA - Small nuclear RNA\nhnRNA - Heterogenous nuclear RNA\nSatyanarayana- Biochemistry, 3rd edition, pg-549', 'role': 'assistant'}]