This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'In apoptosis, cytochrome C acts through - \nSelect and explain. \nA. Apaf 1, B. Bcl-2, C. FADD, D. TNF', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Apaf 1o One of these proteins is cytochrome c, well known for its role in mitochondrial respiration. In the cytosol, cytochrome C binds to a protein called Apaf-1 (apoptosis activating factor-1), and the complex activates caspase-9. (Bc1-2 and Bcl-x may also directly inhibit Apaf-1 activation, and their loss from cells may permit activation of Apaf-1).", 'role': 'assistant'}]