This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Peripheral blood smear examination of a post splenectomy patient would show the presence of: \nSelect and explain. \nA. Dohle bodies, B. Hypersegmented neutrophils, C. Spherocytes, D. Howell-Jolly bodies', 'role': 'user'}, {'content': 'Answer: D \nExplanation: In the absence of a functional spleen, nuclear remnants are not culled from the red cells and remain as small homogeneously staining blue inclusions, known as Howell-Jolly bodies. Dohle bodies are light blue-gray, oval, inclusions located in the peripheral cytoplasm of neutrophils seen in infections, burns physical truma etc. Sphere-shaped red blood cells are known as spherocytes. Spherocytes are found in hereditary spherocytosis and autoimmune hemolytic anemia. Hypersegmented neutrophils are seen in vitamin B12 deficiency. Ref: Harrisons principles of internal medicine, 18th edition, chapter: 57', 'role': 'assistant'}]