This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: NSAIDs, Gout and Rheumatoid Ahritis, Subject name: Pharmacology
[{'content': 'Among NSAIDs aspirin is unique because it: \nSelect and explain. \nA. Irreversibly inhibits its target enzyme, B. Reduces the risk of colon cancer, C. Reduces fever, D. Selectively inhibits COX-2 enzyme', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Aspirin is the only irreversible COX inhibitor. Most NSAIDs can reduce the risk of colon cancer. Selective COX-2 inhibitors like celecoxib are used to prevent risk of colon cancer in patients with familial adenomatous polyposis coli. All NSAIDs have anti-pyretic activities. Selective COX-2 inhibitors include celecoxib, etoricoxib like drugs Aspirin is non-selective COX inhibitor.', 'role': 'assistant'}]