This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': "Alzheimer's disease associated chromosome is \nSelect and explain. \nA. 2, B. 6, C. 12, D. 19", 'role': 'user'}, {'content': 'Answer: D \nExplanation: In familial Alzheimer disease and down syndrome. The gene encoding APP on chromosome 21 is involved.\nThe genitic locus on chromosome 19 that encodes apolipoprotein E (ADOE) has a strong inthences on the risk of developing AD.', 'role': 'assistant'}]