This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Which is the most specific tumor marker for melanoma: \nSelect and explain. \nA. Tyrosinase, B. Vimentin, C. S-100, D. HMB-45', 'role': 'user'}, {'content': 'Answer: D \nExplanation: HMB-45 is the most specific tumor marker for melanoma. S-100 is most sensitive.', 'role': 'assistant'}]