This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunology, Subject name: Microbiology
[{'content': 'N. meningitis can be due to deficiency of this complement system: \nSelect and explain. \nA. C1 - C4 deficiency, B. C5 - C9 deficiency, C. C3 deficiency, D. C2 deficiency', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ref: Textbook of Microbiology by Surinder Kumar, P 262* Meningococcal disease is favoured by deficiency of the terminal complement components (C5-C9).Human genetic deficiencies of complement components and associated diseasesComplement deficiencyAssociation with diseaseC1 inhibitorHereditary angioneurotic edemaC1Systemic lupus erythematosus-like disease, frequently fatal from overwhelming infectionC2Increased susceptibility to infectionsC3Recurrent bacterial infectionsC4Systemic lupus erythematosus-like diseaseC5Recurrent infections-lupus-like diseaseC6, C7, C8Recurrent infections: Disseminated gonococcal infectionsC9Not more susceptible to disease than other individuals in the general populationFactor 1Low C3 levels with recurrent bacterial infections', 'role': 'assistant'}]