This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetic and genetic disorders, Subject name: Pediatrics
[{'content': 'A paicular genetic disorder appears in three consecutive generations of a family without any sex predilection. It was also noticed that phenotypically normal family members were having healthy offspring . What is the pattern of inheritance in this disorder? \nSelect and explain. \nA. Autosomal recessive, B. Autosomal dominant, C. Mitochondrial inheritance, D. Uniparenteral disomy', 'role': 'user'}, {'content': 'Answer: B \nExplanation: The pattern of inheritance in this disorder is autosomal dominant. Points in our: Autosomal dominant disorders have a veical mode of transmission (individuals of two generations are affected-Parent and children affected) Genetic disorder has appeared in three consecutive generations of a family without any sex predilection, and normal family members have healthy offspring. An affected individual has 50% chance of passing on the deleterious gene in each pregnancy Males and females are equally affected. Unaffected individuals donot pass on the disorder to their children Autosomal Dominant Ref: Nelson textbook of pediatrics 21st edition Pgno: 640', 'role': 'assistant'}]