This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hemoglobinopathies: Sickle cell anemia, Subject name: Pathology
[{'content': 'Bone infarcts are seen in: \nSelect and explain. \nA. Iron deficiency anemia, B. Thalassemia, C. Sickle cell anemia, D. Hereditary spherocytosis', 'role': 'user'}, {'content': 'Answer: C \nExplanation: - Sickled cells can cause microvascular occlusion affecting Bones - Hand foot syndrome; Avascular necrosis of femur; H-shaped/ cod-fish/ fish mouth veebra. Brain - coma/ altered consciousness/ stroke, Skin - chronic, non-healing ulcer Spleen - autosplenectomy Pulmonary circulation - Acute chest syndrome', 'role': 'assistant'}]