This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Large intestine, Subject name: Surgery
[{'content': "Most common presentation of Hirschsprung's disease \nSelect and explain. \nA. Abdominal distention, B. Vomiting, C. Failure to pass meconium, D. Failure to thrive", 'role': 'user'}, {'content': 'Answer: A \nExplanation: Clinical Presentation Neonates First few weeks of life Otherwise healthy children and adults Suspected in all neonates presenting with: Delayed passage of meconium beyond the first 24 hours of lifeQ Abdominal distension following feedsQ Suspected in any child presenting in first few weeks of life with: Gross abdominal distensionQ Chronic constipationQ Failure to thriveQ Sho segment Hirschprung disease should be suspected in otherwise healthy children and adultsQ presenting with: Severe constipation without fecal soilingQ Faecal soiling is usually not a feature of this condition. Investigation of choice - Rectal Biopsy (Suction Biopsy > full Thickness Biopsy)', 'role': 'assistant'}]