This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cytogenetic Disorders, Subject name: Pathology
[{'content': 'Which of the following is not due to genetic mutation - \nSelect and explain. \nA. Diabetes mellitus type II, B. Cystic fibrosis, C. Hemophilia, D. Alpha 1 antitrypsin deficiency', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e,, Diabetes meilitus type II o Disorders with multifactorial inheritance :# The multifactorial disorders result from the combined actions of environmental influences and two or more mutant genes having additive effects.o Multifactoriai disorders are:Cleft lip/cleft palateCoronary heart diseaseCongenital heart diseasesHypertensionDiabetes meilitus type IIGoutPyloric stenosiso Other options in question i.e. hemophilia, alpha-1 antitrypsin deficiency, and cystic fibrosis are due t genetic mutations.Note: Diabetes insipidus is X linked recessive disorder due to genetic mutation.", 'role': 'assistant'}]