This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anesthesia, Subject name: Pharmacology
[{'content': 'True statement regarding Bupivacaine is: \nSelect and explain. \nA. Used intravenously along with lignocaine, B. More cardiotoxic than lignocaine, C. Contraindicated in pregnancy, D. All of the above', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Bupivacaine is more cardio toxic than Lignocaine as it more prone to prolong QTc interval and induce ventricular tachycardia or cardiac depression- should not be used for intravenous regional anesthesia. It has high lipid solubility: distributes more in tissues than in blood after spinal or epidural injection . Therefore less likely to reach foetus. Hence used widely in obstetrics . From Tripati 7th edition Page no 367', 'role': 'assistant'}]