This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Targeted Anticancer Drugs and Immunosuppressants, Subject name: Pharmacology
[{'content': 'Which of the following is a new drug recently approved for treatment of neovascular age related macular degeneration? \nSelect and explain. \nA. Brolucizumab, B. Istradefylline, C. Lefamulin, D. Upadacitinib', 'role': 'user'}, {'content': 'Answer: A \nExplanation: *Brolucizumab is a monoclonal antibody against VEGF. *It is recently approved for wet (neovascular) age related macular degeneration.* Istradefylline is adenosine A2 receptor antagonist. It is approved for off episodes in Parkinsonism* Lefamulin is a new antimicrobial that acts by inhibiting protein synthesis. It is approved for community acquired bacterial pneumonia.', 'role': 'assistant'}]