This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Orthopaedics
[{'content': "Epiphyseal enlargement occurs in - \nSelect and explain. \nA. Paget's disease, B. Sheurmann's disease, C. Epiphyseal dysplasia, D. Hemophilia", 'role': 'user'}, {'content': "Answer: D \nExplanation: Epiphyseal enlargement\n\nMost common causes of epiphyseal enlargement are chronic inflammation (e.g. JRA) or chronic increase in blood flow. Causes of Epiphyseal enlargement are:-\n\na)\xa0Solitary (Enlargement of particular epiphysis)\n\nPost-inflammatory (JRA, Septic arthritis)\nPerthe's disease (in repair stage)\nStatus post hip dislocation\nHemophilia (Hemophilic arthropathy)\nTurner syndrome\nKlippel-trenaunay syndrome (angiohypertrophy syndrome)\nKascibach - Merritt syndrome\nBeckwith - Wiedemann syndrome (Hemihypertrophy)\nTrevor disease (Dysplasia epiphysealis hemimelica)\n\nb) Generalized\n\nHyperthyroidism \xa0\xa0\nAcromegaly or cerebral gigantism \xa0 \xa0 \xa0 \xa0\xa0\nAdrenogenital syndrome\xa0\xa0 iv) Rickets\nSpondyloepiphyseal dysplasia\nMcCune-Albright syndrome\nKniest syndrome", 'role': 'assistant'}]