This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Ophthalmology
[{'content': 'Cataract in a diabetic patients is because of accumulation of sorbital in lens. The enzyme responsible for this is \nSelect and explain. \nA. Hexokinase, B. NADPH+ dependant aldolase reductase, C. Glucokinase, D. Phosphofructo isomerase', 'role': 'user'}, {'content': "Answer: B \nExplanation: B i.e. NADPH + dependent aldolase reductase Lens Q, peripheral nerves, renal glomeruli & RBC's are the tissues where glucose can enter without the help of insulin. In diabetics, concentration of glucose rise with in lens which is conveed into sorbitol & fructose. Sorbitol does not easily diffuse through cell membrane & thus accumulate. It causes damage to lens protein and leads to cataract.", 'role': 'assistant'}]