This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pharmacology
[{'content': 'Glyceryl trinitrate is given by sublingual because of \nSelect and explain. \nA. Sho t1/2 in plasma, B. High hepatic first pass metabolism, C. High bioavailability by oral route, D. Extensive protein binding', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Refer kDT 6/e p 7 Main advantage of Sublingual route of drug administration is that liver is bypassed and drugs with high first pass metabolism are absorbed directly into systemic circulation', 'role': 'assistant'}]