This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Social & Preventive Medicine
[{'content': 'Which of the following is best for ante-moem diagnosis of rabies: March 2009 \nSelect and explain. \nA. Antirabies antibodies in blood, B. Immunofluorescence of corneal impressions, C. Immunofluorescence of skin biopsy, D. Isolation of virus from saliva', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans. C: Immunofluorescence of skin biopsy Ante moem diagnosis in human cases is necessary for medical management of the patient and to ensure appropriate post-exposure treatment of contacts. Rabies can be confirmed in patients early in the illness by antigen detection using immunofluorescence of skin biopsy, and by virus isolation from saliva and other secretions. Immunofluorescence of corneal impression smears has proved unreliable. Neutralising antibodies are usually not detected in serum or CSF before the eight day.', 'role': 'assistant'}]