This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Neoplastic disorders of WBCs, Subject name: Pediatrics
[{'content': "A 5-year-old child presents with history of fever off- and-on for past 2 weeks and petechial spots all over the body and increasing pallor for past 1 month. Examination reveals splenomegaly of 2 cm below costal margin. The most likely diagnosis is: \nSelect and explain. \nA. Acute leukemia, B. Idiopathic thrombocytopenic purpura, C. Hodgkin's lymphoma, D. Aplastic anemia", 'role': 'user'}, {'content': 'Answer: A \nExplanation: - Pallor (anemia), petechial spot (thrombocytopenia), fever (infection due to neutropenia) with splenomegaly suggest the diagnosis of acute leukemia. - Splenomegaly eliminates aplastic anemia - Presence of anemia and recurrent infections, go against ITP', 'role': 'assistant'}]