This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Mycology, Subject name: Microbiology
[{'content': 'Coccidioides immitis is identified in tissues on the basis of which of the following \nSelect and explain. \nA. Budding yeast cells with pseudohyphae, B. Yeast like forms with very large capsules, C. Chlamydospore, D. Endosporulating spherules', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Laboratory diagnosis of coccidioidomycosis: 1. Demonstration of spherules containing endospores in: (a) sputum or smears from the lesion stained by calcofluor white and (b) in biopsy material stained by hematoxylin and eosin, silver, or PerIodic acid-Schiff stains. H & E staining', 'role': 'assistant'}]