This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Substance Related and Addictive Disorders, Subject name: Psychiatry
[{'content': 'Korsakoff syndrome true is/are: \nSelect and explain. \nA. Can be seen in chronic alcoholics, B. Absence of intellectual decline, C. Chronic amnestic syndrome, D. All of the above', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Korsakoff syndrome is due to thiamine deficiency. Apa from alcoholism, malnutrition can also cause it. Korsakoff syndrome Chronic neurological complication of long term alcohol use a. Amnesia - Anterograde(m/c) > retrograde b. Learning difficulties c. Confabulations Rx = vitamin B1 oral (Thiamine) for 3 to 12 months * only 20% recover with treatment.', 'role': 'assistant'}]