This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Platelet & Coagulation disorders, Subject name: Medicine
[{'content': 'Bleeding time is increased in all except: \nSelect and explain. \nA. Thrombocytopenia, B. Thrombasthenia, C. Renal failure, D. Acquired hemophilia', 'role': 'user'}, {'content': "Answer: D \nExplanation: aPTT is increased in acquired hemophilia Glanzmann's Thrombasthenia: AR, platelet lack receptor of Gp IIb/IIIa for fibrinogen, which form the bridges between platelets during aggregation. Glanzmann's thrombasthenia is a defect of platelet function(aggregation). It presents as superficial mucocutaneous bleeding with normal platelet count and single isolated platelets without clumping on peripheral smear. Platelet numbers and morphology are normal, but the bleeding time is markedly prolonged. Platelet dysfunction in renal failure is due retention of uremic toxins, anemia,and nitric oxide.", 'role': 'assistant'}]