This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Virology, Subject name: Microbiology
[{'content': 'Which of these hepatitis viruses replicates its genome in the nucleus of the host hepatocyte? \nSelect and explain. \nA. HBV, B. HCV, C. HEV, D. HAV', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. A. HBVHepatitis B is the only hepatitis virus with a DNA genome (thus requiring entry into the nucleus for transcription of the genome into mRNA).', 'role': 'assistant'}]