This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General Concepts, Subject name: Pathology
[{'content': 'Cell-matrix adhesions are mediated by? \nSelect and explain. \nA. Cadherins, B. Integrins, C. Selectins, D. Calmodulin', 'role': 'user'}, {'content': 'Answer: B \nExplanation: The cell adhesion molecules (CAMs) are classified into four main families:- * Immunoglobulin family CAMs *Cadherins * Integrins: bind to extracellular matrix (ECM) proteins such as fibronectin, laminin, and osteopontin providing a connection between cells and extracellular matrix (ECM) * Selectins', 'role': 'assistant'}]