This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Xeroderma pigmentosum is produced as a result of a defect in: \nSelect and explain. \nA. DNA polymerase III, B. DNA polymerase Iand DNA ligase, C. DNA exonuclease, D. DNA ligase', 'role': 'user'}, {'content': "Answer: B \nExplanation: Xeroderma pigmentosm cells are defective in Nucleotide Excision Repair. In NER, the wrong base is removed by endonuclease. This option is not given here. So other enzymes involved in the NER are DNA polymerase I & DNA ligase. Ref: Harper's Biochemistry, 26th Edition, Page 337 ; Text book of Biochemistry By D M Vasudevan, 5th Edition, Pages 420, 421", 'role': 'assistant'}]