This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti-Viral, Subject name: Pharmacology
[{'content': 'NRTI which has maximum tendency to cause peripheral neuropathy \nSelect and explain. \nA. Zidovudine, B. Stavudine, C. Lamivudine, D. Didanosine', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans. (b) StavudineRef KDT 6th ed. / 770* NRTIs are reverse transcriptase inhibitors, which control the dsDNA formation from ssRNA* Drugs in the category are: Zidovudine, Stavudine, Didanosine, Lamivudine, Abacavir, Zalcitabine.Also Know* ZIDOVUDINE# Most commonly used NRTI in the treatment of HIV# Used as prophylaxis in needle stick injury and to decrease vertical transmission from HIV mother to fetus.# Side effect: bone marrow suppression.* Drug of choice for decreasing vertical transmission from HIV mother to fetus: NEVIRAPINE* Safest NRTI: LAMIVUDINE* All NRTIs casues acute pancreatitis and peripheral neuropathy.# Maximum risk of acute pancreatitis with: DIDANOSINE# Maximum risk of peripheral neuropathy with: STAVUDINE', 'role': 'assistant'}]