This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Autacoids, Subject name: Pharmacology
[{'content': 'Tolerance develops to all of the following effects of opioids except \nSelect and explain. \nA. Constipation, B. Miosis, C. Convulsions, D. All of the above', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Decreased effects are seen with continuous usage of opioids except for miosis, constipation, and convulsions.Ref: HL Sharma 3rd ed Pg: 508', 'role': 'assistant'}]