This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Central Nervous system, Subject name: Pharmacology
[{'content': 'All of the following can be used to treat heroin dependence except: \nSelect and explain. \nA. Disulfiram, B. Buprenorphine, C. Clonidine, D. Lofexidine', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ref: Goodman and Gilman 12th/660-661 *Disulfiram is used for alcohol de-addiction and not for opioid. *Methadone or Buprenorphine are used to prevent withdrawal symptoms. *Alpha 2 Agonists like clonidine and lofexidine are used to treat sympathetic withdrawal symptoms of opioid addiction.', 'role': 'assistant'}]