This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'An Afroamerican boy of 6 years of age presented with abdominal pain, chronic hemolysis and abnormal RBC shape on peripheral smear. Most likely disorder responsible for this condition is - \nSelect and explain. \nA. Trinucleotide repeat, B. Point mutation, C. Antibodies against RBC membrane, D. Genetic imprinting', 'role': 'user'}, {'content': 'Answer: B \nExplanation: . Point mutation', 'role': 'assistant'}]