This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'MRP2 gene defect results in which of the hereditary disorders of bilirubin metabolism and Transpo is: \nSelect and explain. \nA. Gilbes, B. Crigler najjar type I, C. Crigler najjar type II, D. Dubin johnson-', 'role': 'user'}, {'content': "Answer: D \nExplanation: PARAMETER Syndrome GILBE'S CRIGLER- NAJJAR TYPE I CRIGLER-NAJJAR TYPE II DUBIN-JOHNSON ROTOR'S Incidence 6%-12% Very rare Uncommon Uncommon Rare Gene affected UGT1A1 UGT1A1 UGT1A1 MRP2 Unknown Metabolic defect |Bilirubin conjugation No bilirubin conjugation ||Bilirubin conjugation Impaired canalicular expo of conjugated bilirubin Impaired canalicular expo of conjugated bilirubin Ref:Sleisenger and Fordtran's,E-9,P-326.", 'role': 'assistant'}]