This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Renal carcinoma, Subject name: Pathology
[{'content': 'True statements about renal cell carcinoma except? \nSelect and explain. \nA. Asbestos, sickle cell anemia & petroleum products are risk factors, B. Clear cell cancer arise from proximal convoluted tubule, C. Cannon ball metastasis, D. Bellini duct cancer arise from loop of henle.', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Bellini duct cancer arise from the collecting duct cells in medulla & not the Loop of Henle. Risk factors of Renal Cell Carcinoma : Cigarette smokers have double the incidence of renal cell carcinoma Tobacco HTN /obesity/estrogen Asbestos Sickle cell anemia Petroleum products Clear cell carcinoma arises from Proximal convoluted Tubule. Cannon ball opacities on chest x-ray suggest metastatic malignancies such as choriocarcinoma, lung carcinoma, renal cell cancer, or endometrial carcinoma.', 'role': 'assistant'}]