This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous (Bio-Chemistry), Subject name: Biochemistry
[{'content': "Wernicke's encephalopathy occurs due to deficiency of \nSelect and explain. \nA. Vitamin B1, B. Vitamin B2, C. Vitamin B6, D. Vitamin B12", 'role': 'user'}, {'content': "Answer: A \nExplanation: (A) Vitamin B1 # Dry Beriberi involves both the peripheral and the central nervous systems.> Peripheral nerve involvement is typically asymmetric motor & sensory neuropathy with pain, paresthesias& loss of reflexes.> The legs are affected more than the arms. Central nervous system involvement results in Wernicke-Korsakoff syndrome.> Wernicke's encephalopathy consists of nystagmus progressing to ophthalmoplegia, truncal ataxia & confusion> Koraskoff's syndrome includes amnesia, confabulation, and impaired learning.", 'role': 'assistant'}]