This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pharmacology
[{'content': 'Drugs of the choice for central diabetes insipidus is \nSelect and explain. \nA. Desmopressin, B. Leuprolide, C. Thiazide diuretics, D. Insulin', 'role': 'user'}, {'content': 'Answer: A \nExplanation: *Desmopressin is treatment of choice for central diabetes insipidus. *It acts selectively at V2 receptors to increase urine concentration and decrease urine flow in a dosedependent Manner. *It is also more resistant to degradation than AVP and has a three- to fourfold longer duration of action. *Desmopressin can be given by IV or SC injection,nasal inhalation,or oral tablet.', 'role': 'assistant'}]