This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of carbohydrate, Subject name: Biochemistry
[{'content': 'The activity of pyruvate carboxylase is dependent upon the positive allosteric effector \nSelect and explain. \nA. Succinate, B. AMP, C. Isocitrate, D. Acetyl Co A', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Pyruvate carboxylase is an allosteric enzyme. Acetyl CoA is an activator of pyruvate carboxylase so the generation of oxaloacetate is ored when acetyl CoA level is sufficiently high.Ref: DM Vasudevan, 7th edition, page no: 120', 'role': 'assistant'}]