This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Screening for Disease, Subject name: Social & Preventive Medicine
[{'content': 'A patient with cervical cancer is missed by a screening test and later diagnosed to have advanced disease. This time interval is called: \nSelect and explain. \nA. Lead time, B. Screening time, C. Serial interval, D. Generation time', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ref: K. Park, Textbook of Preventive and Social Medicine.22nd edition. P 127: Text book of public health and community medicine. Armed Force Medical College, Pune. First edition 2009 p 136. p224Explanation:Lead time:Lead time is defined as the interval between the point a condition is detected through screening and the time it would normally have been detected due to appearance and reporting of signs and symptoms.It is the advantage gained by screeningScreening time:The time interval between the point a condition is detected through screening and final critical diagnosis by other means before usual time of diagnosis.Serial Interval: The gap in time between the onset of the primary case and the secondary case is called the \'"serial interval".Generation time:It is defined as "the interval of time between receipt of infection by a host and maximal infectivity of that host"', 'role': 'assistant'}]