This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Deficiency of E-cadherin is seen in? \nSelect and explain. \nA. Intestinal carcinoma, B. Thyroid carcinoma, C. Colon cancer, D. Gastric cancer', 'role': 'user'}, {'content': 'Answer: D \nExplanation: E-cadherin (CDH-1) deficiency is seen in Gastric cancer and lobular breast cancer.', 'role': 'assistant'}]