This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': 'The drug of choice in treatment of inflantile spasms is \nSelect and explain. \nA. Phenytoin, B. Phenobarbitone, C. Carbamazepin, D. ACTH', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Infantile spasms:-\n\nWest syndrome\nOnset : 3-8 months of life\nCharacterised by combination of salaam spells( sudden dropping of the head and flexion of arms), developmental retardation, hypsarrythmia on ECG.\n\nCauses-\n\nHypoxic ischemic encephalopathy\nNeurocutaneous syndromes\nPerinatal infections\nHemorrhage\nInjury\nMetabolic disorders\nLocalized structural malformations\xa0\nThe spasms occur in clusters usually on waking\n\nDrug therapy-\n\nIntramuscular ACTH 40-60 unit per day may be given 4-6 weeks and tgen tapered off.\nOn the other hand oral prednisolone at 2 mg/ kg / day in divided doses may also be used.\nThese agents abolish spasms and may result in resolution of hypsarrythmia.', 'role': 'assistant'}]