This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Urinary tract, Subject name: Pathology
[{'content': 'Which one of the following is not a feature of adult polycystic kidney disease? \nSelect and explain. \nA. Hypeension, B. Intermittent renal colic, C. Massive proteinuria, D. Macroscopic haematuria', 'role': 'user'}, {'content': 'Answer: C \nExplanation: The most frequent and earliest presenting feature is a dull ache in the lumbar regions. In others, the presenting complaints are haematuria or passage of blood clots in urine, renal colic, hypeension, urinary tract infections and progressive CRF with polyuria and proteinuria. Ref: Harsh Mohan textbook of pathology 6th edition page 658', 'role': 'assistant'}]