This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Inflammation & Repair, Subject name: Pathology
[{'content': 'The following is not a pyrogenic cytokine \nSelect and explain. \nA. IL-1, B. TNF, C. Substance P, D. Prostaglandins', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans. (c) Substance P(Ref: J Infect Dis. (1999) 179 (Supplement 2): S294-S304. doi: 10.1086/513856, Harrison 18th ed:2666.)IL1 AND TNF are well known pyrogenic cytokines In the hypothalamus, the prostaglandins, especially PGE2, stimulate the production of neurotransmitters that reset the temperature set point at a higher level, hence pyrogenic', 'role': 'assistant'}]