This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Eczema and related disorders, Subject name: Dental
[{'content': 'Contact dermatitis is a type of Hypersensitivity \nSelect and explain. \nA. Type I, B. Type II, C. Type III, D. Type IV', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Table 74.1 CLASSIFICATION OF ADVERSE DRUG REACTIONS BASED ON IMMUNE PATHWAY Type Key Pathway Key Immune Mediators Adverse Drug Reaction Type Type I IgE IgE Uicaria, angioedema, anaphylaxis Type II IgG-mediated cytotoxicity IgG Drug-induced hemolysis, thrombocytopenia (e.g. penicillin) Type III Immune complex IgG + antigen Vasculitis, serum sickness, drug-induced lupus Type IV a T lymphocyte-mediated macrophage inflammation IFN-g, TNF-a TH1 cells Tuberculin, skin test, contact dermatitis Type IV b T lymphocyte-mediated eosinophil inflammation IL-4, IL-5, IL-13 TH2 cells Eosinophils Drug-induced hypersensitivity syndrome (DIHS)Morbilliform eruption Type IV c T lymphocyte-mediated cytotoxic T lymphocyte inflammation Cytotoxic T lymphocytes GranzymePerforin Granulysin (Stevens-johnson syndrome (SJS)/ toxic epidermal necrolysis (TEN) only) SJS/TEN Morbilliform eruption Type IV d T lymphocyte-mediated neutrophil inflammation CXCLB, IL-17, GM-CSF Neutrophils Acute generalized exanthematous pustulosis (AGEP)', 'role': 'assistant'}]