This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
[{'content': 'Which of the following statement about lepromin test is not true? \nSelect and explain. \nA. It is negative in most children in first 6 months of life, B. It is a diagnostic test, C. It is an important aid to classify type of leprosy disease, D. BCG vaccination may convert lepra reaction from negative to positive', 'role': 'user'}, {'content': 'Answer: B \nExplanation: The lepromin test is used to study host immunity to M.leprae.\nThe test was first described by Mitsuda in 1919. The test is an intradermal skin test performed by using lepromin antigen, which is a suspension of killed M. leprae obtained from infected human or armadillo tissue.\nThe lepromin test is not used to confirm the diagnosis of leprosy. It is also not useful to indicate prior contact of the person with leprae bacilli. Healthy people residing in areas nonendemic for leprosy with no chance of contact with the bacilli may show a positive lepromin reaction.\n\nKey Points:-\nThe lepromin test is used mainly to:\n\nDetermine the type of leprosy, being positive (suggests resistance to disease) in tuberculoid leprosy and negative (suggests a lack of resistance to the disease) in lepromatous leprosy patients.\nMonitor\xa0the response of leprosy patients to treatment with chemotherapy. A positive reaction indicates a good prognosis, while a negative test suggests a very bad prognosis.\nEvaluate host resistance to leprosy.\n\nParija SC. Textbook of Microbiology & Immunology. Elsevier Health Sciences; 2014. Page: 368', 'role': 'assistant'}]