This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy: General Principles, Subject name: Pharmacology
[{'content': 'All of the following anticancer drugs act on G2 phase except: \nSelect and explain. \nA. Paclitaxel, B. Etoposide, C. Irinotecan, D. Bleomycin', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. (A) Paclitaxel(Ref: Katzung 13th/e p921)Paclitaxel is a taxane that act on mitotic spindle. Drugs acting on mitotic spindle act on M phase of cell cycle.Phase of cell cycleDrugs actingG1EtoposideSAntimetabolitesG2BleomycinEtoposideIrinoctecanTopotecanMVinca alkaloidsTaxanes', 'role': 'assistant'}]