This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Dental
[{'content': "25 years old male having fever & malaise for 2 weeks, arthritis of ankle joint and tender erythema-tons nodules over the shin. Diagnosis is – \nSelect and explain. \nA. Erythema nodosum, B. Hensen's disease, C. Weber–christian disease, D. Urticarial vasculitis", 'role': 'user'}, {'content': 'Answer: A \nExplanation: This one is about the differential diagnosis of panniculitis.\nPanniculitis refers to a broad spectrum of disease that involves inflammation of the fatty layer of the skin\n\n\nThe tissue layer under the skin (epidermis and dermis) is called the subcutaneous fat or panniculus.\nInflammation of this layer of fatty tissue is called panniculitis\nDue to panniculitis, the overlying skin appears as a red or purplish lump.\n\n\nBoth erythema nodosum and weber Christian disease are characterized by panniculitis.\nTheir clinical presentation is quite similar and there is not much to separate the two diseases.\n\n\nBoth the diseases present with tender erythematous nodules on the lower legs.\nSystemic features such as fever, malaise, weight loss and arthralgia are seen in both the disease.\n\nFacts which favour the diagnosis of erythema nodosum in the question\n\nThe lesions in Weber Christian disease are bilateral and symmetrical\nThe clinical course of Weber Christian disease is characterized by exacerbations and remissions\nThe involved areas manifest as recurrent crops of erythematous tender nodules.\nIt is a rare disease and is usually seen in elderly females (30-60 yrs).\nThe patient in the question gives a history of fever & malaise for 2 weeks which is a classic feature of erythema nodosum (erythema nodosum is associated with preceding streptococcal infection).', 'role': 'assistant'}]