This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Dental
[{'content': 'Destruction of the enamel knot leads to: \nSelect and explain. \nA. Cessation of further tooth development., B. Dentinogenesis imperfecta., C. Amelogenesis imperfecta., D. None.', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Enamel knot is an important signalling centre for the proliferation and growth of the dental papilla.\nDestruction of enamel knot leads to cessation of further tooth development.', 'role': 'assistant'}]