This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': "In which of the following conditions, Aniridia and Hemihypertrophy are most likely present - \nSelect and explain. \nA. Neuroblastoma, B. Wilm's tumour, C. Non-Hodgkin's lymphoma, D. Germ cell tumour", 'role': 'user'}, {'content': "Answer: B \nExplanation: Wilm's tumour is associated with three groups of congenital malformations.\nThe risk of Wilm's tumour is increased in these conditions.\nThese are -\n\n1. WAGR syndrome - It consists of\n\nAniridia\xa0\xa0\xa0\xa0\nMental retardation\nGenital anomalies\n\nThe risk of Wilm's tumour is increased by 33% in this syndrome.\n\n2. Denys-Drash syndrome - It consists of\n\nGonadal dysgenesis (male pseudohermaphroditism)\nNephropathy leading to renal failure.\n\nMajority of patients with this syndrome have a ranal failure.\n\n3. Beckwith - Wiedemann syndrome - It consists of\n\nEnlargement of body organs \xa0 \xa0 \xa0 \xa0 \xa0\xa0\nHemihypertrophy \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0 \xa0\nRenal medullary cysts.\nAbnormal large cells in the adrenal cortex.", 'role': 'assistant'}]