This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nervous System, Subject name: Physiology
[{'content': 'Massage and the application of ligaments to painful areas in the body relieves pain due to- \nSelect and explain. \nA. Stimulation of endogenous analgesic system, B. Release of endorphins by the first order neurons in the brain stem, C. Release of glutamate and substance P in the spinal cord, D. Inhibition by large myelinated afferent fibres', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans. D. Inhibition by large myelinated afferent fibresa. Pain:Receptors: naked nerve ending (free nerve ending found in almost every tissues of the body. & Tract Antolateral- spinothalamic tractTypes of PainNerve fiber involved in transmissionSynaptic transmitters1. Fast mild pain (first or fast pain)Small diameter myelinated A li fibers; terminate primarily on neurons in laminas I and V of dorsal hornGlutamate2. Slow severe pain (slow or second pain)Unmyelinated C-fiber; terminate primarily on neurons in laminas I and II of dorsal hornSubstance -P', 'role': 'assistant'}]