This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Bleeding Disorders, Subject name: Pathology
[{'content': "Glanzman's thromboasthenia is characterized by defective - \nSelect and explain. \nA. Gp IIB/IIIA, B. Gp IB/IX, C. Gp IB/IIIA, D. GpIIB/IX", 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans is 'a' Gp IIB/IIIA Glanzman's thrombastheniao It is an autosomal recessive disorder due to deficiency/dysfunction of glycoprotein Ilb-IIla (Gp Ilb/IIIa). Thus there is defective platelet aggregation.o Platelet aggregation is normal to ristocetin(ln constant to Bernard soulier syndrome) but no aggregation occurs in response to standard agonists (collagen, A DP, thrombin).o Other differentiating features include normal platelet count and morphologyo BT is prolonged. vWF is normal.o The disease manifests at birth with increased bleeding from umbilical cord stump.", 'role': 'assistant'}]