This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Which of the following cephalosporins does not need dose modifications even in presence of decreased GFR- \nSelect and explain. \nA. Cefipine, B. Cefoperazone, C. Cefotaxim, D. Cefuroxine', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., Cefoperazone o Cefoperazone is primarily exreted in bile in contrast to other cephalosporins that are usually excreted by the kidney --> safe in renal failure. o Cephalosporins that can be used in presence of renal failure :- i) Cefoperozone, ii) Ceftriaxone, iii) Cefoperamide", 'role': 'assistant'}]