This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
[{'content': 'Reaction due to lysis of bacterial cell wall &necrotic cell product ? \nSelect and explain. \nA. Ahus reaction, B. Serum sickness, C. Jerish herheximer reaction, D. Infectious mononucleosis-ampicillin reaction', 'role': 'user'}, {'content': "Answer: C \nExplanation: Ans. is 'c' i.e., Jerish herheximer reaction Ceain cell wall acting antibiotics cause rapid cell lysis and release of proinflammatory and/or toxic bacterial components, which induce inflammatory response in host. This produces a clinical syndrome known as Jarish-hersheimer reaction. The typical example is treatment of primary and secondary syphilis with penicillin, which may produce fever, malaise and exacerbation of symptoms due to Jarish -hersheimer reaction. The reaction can be managed with antipyretics and antihistaminics. About other options Ahus reaction and serum sickness are type III hypersensitivity reactions due to formation of antigen- antibody complex. In IMN, ampicillin causes rash but this is due to allergic reaction against ampicillin.", 'role': 'assistant'}]