This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Which one of the following is not a feature of liver histology in Non-cirrhotic portal fibrosis (NCPF)? \nSelect and explain. \nA. Fibrosis in and around the portal tracts, B. Thrombosis of the medium and small portal vein branches, C. Non specific inflammatory cell infiltrates in the portal tracts, D. Bridging fibrosis', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Fibrosis in noncirrhotic portal fibrosis is confined to portal and periportal region.\nFibrosis bridging one portal tract to another (bridging fibrosis) is not seen.\nPathology :\n\nNon-cirrhotic portal fibrosis is primarily a vascular disorder of the liver characterized by fibrous intimal thickening\xa0of the portal vein or its branches in patients with non-cirrhotic portal hypertension.\n\nVascular changes\n\nHallmark of the disease is thrombosis/sclerosis of the portal vein branches.\nThe portal vein is dilated with sclerosis of the walls and in autopsy thrombin, in medium or small portal vein branches with accompanying areas of ischaemic necrosis have been reported.\nAberrant Intrahepatic vessels may be present in the periportal area, which correspond to dilated terminal portal\xa0vein branches or venues. These are often termed as "megasinusuoids" or periportal angiomatosis.\n\nFibrosis\n\nVascular changes are accompanied by the portal and periportal fibrosis of varying extent.', 'role': 'assistant'}]