This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Which among the following may be used as a sedatives-hypnotic? \nSelect and explain. \nA. Zolmitriptan, B. Zileuton, C. Zolpidem, D. Zalcitabine', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Zolpidem\u200b\nThe hypnotic zolpidem is not structurally related to benzodiazepines, but it selectively binds to the benzodiazepine receptor subtype BZ1. Zolpidem has no anticonvulsant or muscle-relaxing properties. \u200b\nIt shows few withdrawal effects, exhibits minimal rebound insomnia, and little tolerance occurs with prolonged use. Zolpidem is rapidly absorbed from the gastrointestinal (GI) tract, and it has a rapid onset of action and short elimination half-life (about 2 to 3 hours). It provides a hypnotic effect for approximately 5 hours.\u200b\n\u200bZolmitriptan is one of the drugs used to treat migraine headache.\xa0\u200b\u200b\u200b\nZileuton is a selective and specific inhibitor of 5-lipoxygenase, preventing the formation of both LTB4\u200b\xa0 and the cysteinyl leukotrienes. These drugs are useful for treatment of asthma in patients who are poorly \u200bcontrolled by conventional therapy.\u200b\nKey Concept: \u200b\nZolpidem (AMBIEN, others) is a non-benzodiazepine sedative-hypnotic drug. \u200b\nReference: Lippincott Illustrated Reviews: Pharmacology Wolters Kluwer Sixth Edition page no 129, 465,385;\u200b Goodman and Gillman, the Pharmacological basis of Therapeutics 12 ed page no 467\u200b', 'role': 'assistant'}]