This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'In megaloblastic anemia, the cells are: \nSelect and explain. \nA. Macrocytic hyperchromic, B. Macrocytic hypochromic, C. Macrocytic normochromic, D. None of the above', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Megaloblastic Anemia \nThe blood film can point towards vitamin deficiency:\n\nDecreased red blood cell (RBC) count and hemoglobin levels.\nIncreased mean corpuscular volume (MCV\xa0>100 fL) and mean corpuscular hemoglobin (MCH).\nNormal mean corpuscular hemoglobin concentration (MCHM = 32-36 g/dL).\xa0\nDecreased reticulocyte count\xa0due to destruction of fragile and abnormal megaloblastic erythroid precursor.\xa0\nThe platelet count may be reduced.\nNeutrophil granulocytes may show multisegmented nuclei ("senile neutrophil”). This is thought to\xa0be due to decreased production and a compensatory prolonged lifespan for circulating neutrophils,\xa0which increase the numbers of nuclear segments with age.\nAnisocytosis (increased variation\xa0in RBC size) and poikilocytosis (abnormally shaped RBCs).\nMacrocytes (larger than normal RBCs) are present.\nOvalocytes (oval-shaped RBCs) are present.\nHowell-Jolly bodies (chromosomal remnant) also present.', 'role': 'assistant'}]