This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
[{'content': 'In Marfan&;s syndrome defect is in \nSelect and explain. \nA. Fibrillin I, B. Fibrillin II, C. Collagen, D. Elastin', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Marfan syndrome is caused by a mutation in FBNI gene encoding fibrillin. The major tissue effected are skeleton, eyes and cardiovascular system Refer robbins 146', 'role': 'assistant'}]