This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: FMGE 2017, Subject name: Pathology
[{'content': 'Which of the following condition is characterized by presence pf hyaline deposits in alveolar walls? \nSelect and explain. \nA. Interstitial lung disease, B. Asthma, C. Hyaline membrane disease, D. Chronic bronchitis', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Neonates HMD ( Hyaline membrane disease composition:- fibrin ) Respiratory distress syndrome Adults ARDS(Adult respiratory distress syndrome) Usually caused due to damage of endothelial cells Subsequently injury to TYPE 1 and TYPE 2 pneumocytes ARDS:- Characterized by Acute shoness of breath Hypoxemia Diffuse pulmonary infiltrates Diagnosis of ARDS : onset <7 days Non cardiogenic pulmonary edema B/L diffuse infiltrates on chest X-ray Pao2 < 60 mmHg Pao2/Fio2 < 60mmHg Hyaline membrane disease: -Deposition of layer of hyaline proteinaceous material in peripheral airspaces of infants 200-300 (Mild ARDS) 100-200 (Moderate ARDS) < 100 Severe ARDS Causes of RDS: immaturity of lungs (most impoant substrate on which RDS develops) Occurs in about 60% of infants born <28 wks Occurs in 30% of infants born b/w 28-34 wks Fundamental defect in RDS is deficiency of pulmonary surfactant (predominantly dipalmitoyl phosphatidyl choline smaller amounts of phosphatidyl glycerol) Interstitial lung disease: Predominant involvement of interstitium progressing to fibrosis IOC: HRCT chest Radiological pattern: Reticular pattern CT chest: mild lazy ness K/a ground glass opacity', 'role': 'assistant'}]