This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Hereditary retinoblastoma develop as a result of which of the following chromosomal deletion? \nSelect and explain. \nA. 13q 14, B. 13p 14, C. 14p 13, D. 14q 13', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Hereditary retinoblastomas develop from the deletion of Rb gene, located on chromosome 13q14. Retinoblastoma gene is a tumor suppressor gene, which serves as a break on the advancement of cells from the G1 to S phase of cell cycle.Ref: Robbins Pathologic Basis of Disease, 7th Edition, Pages 287, 289, 1372.', 'role': 'assistant'}]