This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Targeted Anticancer Drugs and Immunosuppressants, Subject name: Pharmacology
[{'content': 'Immunosuppressant drug inhibiting the action of IL-2 without inhibiting its transcription is: \nSelect and explain. \nA. Prednisolone, B. Cyclosporine, C. Tacrolimus, D. Sirolimus', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Cyclosporine and tacrolimus are calcineurin inhibitors. These inhibit the formation (gene transcription) of interleukins. Sirolimus is mTOR inhibitor. It inhibits the action of interleukins after their formation.', 'role': 'assistant'}]