This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Which of the following anti histamine should be avoided in a truck driver with rhinitis? \nSelect and explain. \nA. Diphenhydramine, B. Astemizole, C. Desloratadine, D. Fexofenadine', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Diphenhydramine\xa0 is a 1st generation anti-histamine which has highly sedating property and hence should be avoided in truck drivers and swimmers.', 'role': 'assistant'}]