This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': 'Male pseudohermaphroditism is seen in – \nSelect and explain. \nA. 5–α reductase deficiency, B. 17 hydroxylase deficiency, C. Gonadal dysgenesis, D. All the above', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Male pseudohermaphroditism\n\nGenotype is XY\nExternal genitalia are female\n\nCauses of Male Pseudohermaphroditism\nA. A defect in testicular differentiation\n\nDeletion of the short arm Y chromosome\xa0\nXY pure gonadal dysgenesis.\xa0\nMixed gonadal dysgenesis (MGD).\nDysgenetic male pseudohermaphroditism (DMP).\xa0\xa0\n\nB. A defect in testicular hormone synthesis\n1. Leydig cell aplasia\n2. Inborn error of testosterone biosynthesis\n\n17-alpha hydroxylase deficiency \xa0 \xa0 \xa0 \xa0\n17-20 lyase deficiency \xa0 \xa0\xa0\n17-ketosteroid reductase deficiency.\n3 beta-hydroxysteroid dehydrogenase deficiency.\n20-22 desmolase deficiency\n\nC. A defect in Mullerian inhibiting hormone action\nD. A defect in androgen action\n\n5-alpha reductase deficiency\xa0\xa0\xa0\xa0\xa0\xa0\nTesticular feminization syndrome \xa0 \xa0 \xa0\xa0\nIncomplete testicular feminization syndrome\nReifenstein syndrome\nUndetermined etiology\n\nTrue hermaphroditism\n\nBoth ovarian and testicular tissues are present either in the same (ovotestis) or opposite gonads.', 'role': 'assistant'}]