This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Aspirin should be used with caution in the following groups of patients because of which of the following reason : \nSelect and explain. \nA. In diabetics because it can cause hyperglycemia, B. In children with viral disease, because of the risk of acute renal failure, C. In gout, because it can increase serum uric acid, D. In pregnancy, because of high risk of teratogenicity', 'role': 'user'}, {'content': "Answer: C \nExplanation: At therapeutic doses, Aspirin can cause hyperuricemia by decreasing the excretion of uric acid. It, therefore, should not be used in patients with gout. It also decreases the uricosuric action of probenecid. At high doses (>5 g/ d), it increases the excretion of uric acid, but such high doses are not tolerated.\nAspirin is contraindicated in children (<12 yrs old) due to increased risk of Reye's syndrome, which is a type of he\xadpatic encephalopathy.\nIt should be avoided in diabetics because of risk of hypoglycemia\nIt should be avoided in pregnancy because it may be responsible for low birth weight babies, however, it does not cause congenital malformations.", 'role': 'assistant'}]