This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Biochemical abnormality associated with osteogenesis imperfecta is increase in: \nSelect and explain. \nA. Alkaline phosphatase, B. Acid phosphatase, C. Bicarbonate ion, D. Phosphorylase enzyme', 'role': 'user'}, {'content': 'Answer: D \nExplanation: None', 'role': 'assistant'}]