This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General Pharmacology, Subject name: Pharmacology
[{'content': 'Nitroglycerine is effective when administered sublingually because it is: \nSelect and explain. \nA. Non ionized and lipid soluble, B. Ionized and lipid soluble, C. Non ionized and Water insoluble, D. Ionized and water insoluble', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. (A) Non ionized and lipid soluble(Ref: KDT 8th/e p28)Nitroglycerin is effective when retained sublingually because it is non-ionized and has very high lipid solubility. Thus, the drug is absorbed very rapidly.', 'role': 'assistant'}]