This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Orexins play an impoant role in people with eating disorders. All of the following are orexins, EXCEPT: \nSelect and explain. \nA. Leptin, B. Orexin-A, C. Hypocretin 1, D. Hypocretin 2', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Orexins (A and B) or Hypocretins (1 and 2): They are produced by neurons in the lateral hypothalamus perifornical area. Regulated by glucose, leptin, neuropeptide Y, and POMC neurons. They stimulate food intake. Leptin: It is produced in adipose tissue. Acts on neuropeptide Y, AgRP-containing neurons, and -MSH neurons in the arcuate nucleus of the hypothalamus to decrease food intake. Ref: Molina P.E. (2010). Chapter 10. Endocrine Integration of Energy & Electrolyte Balance. In P.E. Molina (Ed), Endocrine Physiology, 3e.', 'role': 'assistant'}]