This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Serum amyloid associated protein is increased in? \nSelect and explain. \nA. Alzheimer’s disease, B. Ankylosing spondylitis, C. Chronic renal failure, D. Malignant hypertension', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Secondary Amyloidosis (Reactive Systemic Amyloidosis) is associated with amyloid deposits that are\xa0composed of Amyloid Associated Protein (A Protein).\nIt is seen in\n\na) Chronic inflammatory conditions like RA (most common), TB & leprosy, osteomyelitis, ankylosing spondylitis, IBD (Crohn’s disease, UC), bronchiectasis.\nb) Some tumors like Renal cell carcinoma (hypernephroma), Hodgkins lymphoma.\n\nSAA is produced in the liver as an acute phase reactant in the inflammatory process.\nThe SAA is released into the circulation as an amyloid precursor and is transformed to A amyloid in\xa0lysosomes of macrophages and other cells of the reticuloendothelial system.', 'role': 'assistant'}]