This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'A tumor that follows the rule of 10 is- \nSelect and explain. \nA. Pheochromocytoma, B. Oncocytoma, C. Lymphoma, D. Renal cell carcinoma', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Pheochromocytomas\xa0usually subscribe to a convenient\xa0"rule of 10s" :-\n\n\n10% of pheochromocytomas arise in association with one of several familial syndromes.\xa0These include the MEN-2A & MEN-2B syndromes, type I neurofibromatosis, von Hippel-Lindau syndrome & Sturge-Weber syndrome.\n10% of pheochromocytomas are extra-adrenal,\xa0occurring in sites such as organ of Zuckerkandl & carotid body, where these chromaffin-negative tumors are usually called\xa0paragangliomas\xa0to distinguish them from pheochromocytomas.\n10% of nonfamilial adrenal pheochromocytomas are bilateral;\xa0this figure may rise to 70% in cases that are associated with familial syndromes.\n10% of adrenal pheochromocytomas are biologically malignant,\xa0although the associated hypertension represents a serious & potentially lethal complication of even "benign" tumors.\n10% of adrenal pheochromocytomas arise in childhood,\xa0usually the familial subtypes, and with a strong male preponderance. The nonfamilial pheochromocytomas most often occur in adults between 40 & 60 years of age, with a slight female preponderance.', 'role': 'assistant'}]