This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Molecular Genetics, Subject name: Biochemistry
[{'content': 'Retinoblastoma can result from a mutation in: \nSelect and explain. \nA. Ras proto-oncogene, B. ErbB proto-oncogene, C. p 53 gene, D. RB 1 gene', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans. D. RB 1 geneRetinoblastoma is a cancer common in children below 15 years of age. Itis caused by abnormalities of a gene called RB1, which is located on a region of the long (q) arm of chromosome 13 designated 13q14. Although most retinoblastomas are caused by mutations within the RB1 gene, a small percentage of retinoblastomas result from a deletion of the 13q14 region.', 'role': 'assistant'}]