This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Lipid Oxidation and Synthesis, Subject name: Biochemistry
[{'content': 'Rate limiting enzyme in the synthesis of cholesterol is- \nSelect and explain. \nA. HMG CoA reductase, B. HMG CoA synthetase, C. Acetyl CoA synthetase, D. Acetyl CoA carboxylase', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., HMG CoA reductase Cycle / PathwayRate limiting enzymeGlycolysisPhosphofructokinase IGlycogen synthesis (glycogenesis)Glycogen synthaseGlycogenolysisGlycogen phosphorylaseTCA cycleIsocitrate dehydrogenaseFatty acid synthesisAcetyl CoA carboxylaseCholesterol synthesisHMG CoA reductaseKetone body synthesisHMG CoA synthetaseBile acid synthesis7-a-hydroxylaseCatecholamine synthesisTyrosine hydroxylaseUrea synthesisCarbamoyl transferaseNote: Only one important rate limiting enzyme has been mentioned here. Some cycle/ pathways may have more than one rate limiting enzymes, e.g., TCA cycle and glycolysis have three rate limiting enzymes (will be discussed in respective chapter).", 'role': 'assistant'}]