This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'Low TIBC is seen in: \nSelect and explain. \nA. Anemia of chronic disease, B. Iron deficiency anemia, C. Fanconi anemia, D. Aplastic anemia', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. (a) Anemia of chronic diseaseRef: Robbin's pathology 9th ed. /652*In anemia of chronic disease, response to inflammatory cytokines, increasingly IL-6 the liver produces increased amounts of hepcidin.*Hepcidin, in turn, causes increased internalization of ferroportin molecules on cell membranes which prevents the release from iron stores.*Since stores of iron are un-utilized, serum ferritin is increased. TIBC levels are the inverse of serum ferritin.*Low serum iron and ferritin levels with an elevated TIBC are diagnostic of iron deficiency.", 'role': 'assistant'}]