This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Stomach & Duodenum, Subject name: Surgery
[{'content': 'All are true regarding intestinal type of gastric carcinoma Except: \nSelect and explain. \nA. Well defined gland formation, B. Most common site is distal pa of stomach, C. Lymphatic spread, D. More common in elderly', 'role': 'user'}, {'content': "Answer: C \nExplanation: Lauren's classification of stomach cancer Intestinal variety Diffuse variety Classical MC- elderly males (50-60 years) MC site- distal stomach Environmental risk factors Well defined gland formation Hematogenous spread APC gene mutation Epidemic Atypical MC- young females MC site- fundus/proximal stomach Familial risk factors Poor gland formation- signet ring variety Lymphatic spread Decreased E- cadherin Endemic", 'role': 'assistant'}]