This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Pathology
[{'content': 'Which of the following congential anomalies is seen with maternal use of cocaine? \nSelect and explain. \nA. Sacral agenesis, B. Hydrops, C. Cerebral infarction, D. Hyperichosis', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Cocaine - use has been associated with MI, arrhythmias aoic rupture, strokes seizures, bowel ischemia, hypehermia, and sudden death Risk of vascular disruption within the embryo-fetus or placenta is highest after the first trimester and likely accounts for the increased incidence of stillbihs A number of cocaine related congenital anomalies due to vascular based disruption, they include skull defect, cutis aplasia, porencephaly, ileal atresia, cardiac anomalies and visceral infarcts', 'role': 'assistant'}]