This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Urology, Subject name: Surgery
[{'content': 'Imatinib mesylate used in the treatment of GIST is a inhibitor of \nSelect and explain. \nA. IL-12, B. TNF-x, C. Tyrosine kinase, D. VEGE', 'role': 'user'}, {'content': "Answer: C \nExplanation: Imatinib mesylate used in the treatment of GIST ( GastroIntestinal Stromal Tumours) is a c-kit(transmembrane receptor tyrosine kinase) tyrosine kinase inhibitor. GIST is rare but most common nonepithelial small bowel tumours. More than 95% show c-kit mutation. Reference : page 877 SRB's manual of surgery 5th edition", 'role': 'assistant'}]