This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': "Etiology of Quincke's edema: \nSelect and explain. \nA. Sensitivity to acrylic resin, B. Using ACE inhibitors, C. Hereditary, D. All of the above", 'role': 'user'}, {'content': "Answer: D \nExplanation: Common causes of Angio or Quincke’s edema or Giant urticaria\n\nAllergic angioedema due to mast cell degranulation that leads to histamine release. Seen in IgE\xa0mediated hypersensitivity reactions.\nUse of ACE inhibitors, which increase the levels of bradykinin and this form of angioedema usually\xa0arises within hours of initial use of the drug.\nHereditary in which there is reduction of an inhibitor, that prevents the transformation of C1 to C1\xa0esterase that cleaves C4 and C2 and results in angioedema.\nDue to presence of high levels of antigen-antibody complexes (Eg: LE patients).\n\nRef: Shafer's textbook of oral pathology 7th edition page 675", 'role': 'assistant'}]