This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: JIPMER 2017, Subject name: Pharmacology
[{'content': 'All the following drugs are used in the treatment of metastatic breast cancer except: \nSelect and explain. \nA. Ixabepilone, B. Abemaciclib, C. Ribociclib, D. Sunitinib', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Sunitinib is a novel oral multitargeted tyrosine kinase inhibitor with antitumor and antiangiogenic activities. It was recently approved in first-line treatment for patients with advanced renal cell carcinoma (RCC) and for the treatment of patients with gastrointestinal stromal tumors (GIST). Ixabepilone: Antimicrotubule inhibitor(M Phase) : use for breast cancer Abemaciclib and Ribocilib: CDK-4 and CDK-6 inhibitor use in breast cancer', 'role': 'assistant'}]