This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'Hepatosplenomegaly is not seen in: March 2010 \nSelect and explain. \nA. Malaria, B. Lymphoma, C. Sickle cell disease, D. Kala azar', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans. C: Sickle cell disease Some of the common medical causes of hepatosplenomegaly include: Leukemia Lymphoma Bilia atresia Bile duct carcinom Budd Chiari syndrome Spherocytosis Cirrhosis Hepatitis Malaria Thrombocytosis Patient with sickle cell disease often suffer from autosplenectomy as a result of splenic destruction by the numerous infarcts associated with the sickle cell crisis during childhood. Indeed presence of a palpable spleen in a patient with sickle cell disease after age 5 suggests a coexisting hemoglobinopathv', 'role': 'assistant'}]