This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'A 10 year old female patient complains of tiredness and shortness of breath. Patient is a known case of beta-thalassemia. Which of the following can cause this disease? \nSelect and explain. \nA. Terminal base addition, B. Faulty splicing, C. Terminal base deletion, D. None of the above', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Faulty splicing can cause diseases\xa0: Splicing of hnRNA has to\xa0be\xa0performed with\xa0precision to produce functional mRNA. Faulty splicing may result in diseases. A good example is one type of beta-thalassemia in\xa0humans. This\xa0is\xa0due\xa0to\xa0a mutation that results in a nucleotide change at an exon-intron junction. The result is a\xa0diminished or\xa0lack of\xa0synthesis of\xa0 beta-chain of\xa0hemoglobin\xa0and consequently the disease beta-thalassemia.\nSatyanarayana- Biochemistry, 3rd edition, pg-549', 'role': 'assistant'}]