This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunomodulatory: DMARDS, Monoclonal Antibodies, Subject name: Pharmacology
[{'content': 'Tacrolimus level is increased by all except \nSelect and explain. \nA. Erythromycin, B. Itraconazole, C. Danazole, D. Rifampicin', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans. (D) Rifampicinwww.medscape.com/druginfo(Ref: KDT 8/e p940, )Erythromycin, itraconazol and danazol inhibit the metabolism of tacrolimus and thus increase the plasma concentration whereas rifampicin is an enzyme inducer and decrease its plasma level.', 'role': 'assistant'}]