This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Enzyme deficient in Tay Sach disease: \nSelect and explain. \nA. Beta glucosidase, B. Sphingomyelinase, C. Hexosaminidase A, D. Beta galactosidase', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Tay-Sachs diseaseIt is caused by insufficient activity of the enzyme hexosaminidase A.Hexosaminidase A is a vital hydrolytic enzyme, found in the lysosomes, that breaks down glycolipids.When hexosaminidase A is no longer functioning properly, the lipids accumulate in the brain and interfere with normal biological processes.Hexosaminidase A specifically breaks down fatty acid derivatives called gangliosides; these are made and biodegraded rapidly in early life as the brain develops.', 'role': 'assistant'}]