This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'Gold standard method of diagnosing celiac disease is: March 2012 \nSelect and explain. \nA. Small bowel biopsy, B. Anti-endomysial antibodies, C. Blood picture, D. Biochemical tests', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans: A i.e. Small bowel biopsy Diagnosis of celiac disease Endoscopic small bowel biopsy is the gold standard for diagnosing celiac disease IgA anti-endomysial antibodies are detectable by immunofluorescence in most untreated cases. They are not quantitative, but are sensitivie (85-95%) and specific (approximately 99%) for the diagnosis, except in very young infants A full blood count in celiac disease may show microcytic or macrocytic anaemia from iron or folate deficiency and features of hyposplenism (target cells, spherocytes and Howell-Jolly bodies) Biochemical tests may reveal reduced concentrations of calcium, magnesium, total protein, albumin or vitamin D', 'role': 'assistant'}]