This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Medicine
[{'content': 'Plasma ACTH levels are high between these following hours \nSelect and explain. \nA. 4 PM and 8 PM, B. 4 AM and 10 AM, C. 10 AM and 3 PM, D. 10 AM and 2 PM', 'role': 'user'}, {'content': 'Answer: B \nExplanation: (B) 4 AM and 10 AM # ACTH the primary stimulator of adrenal cortisol production is synthesized by pituitary in response to CRH, which is released by hypothalamus.> Plasma ACTH and cortisol levels exhibit peaks at 6-8 AM and nadirs at 11 PM.> Referene values: 10-60 pg for AM values. No established reference values for PM.', 'role': 'assistant'}]