This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy, Subject name: Pharmacology
[{'content': 'Which of the following anticancer drugs acts by hypomethylation? \nSelect and explain. \nA. Gemcitabine, B. 5-FU, C. Decitabine, D. Homoharringotonine', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Decitabine is used to treat myelodysplastic syndromes (diseases of the blood and bone marrow; MDS) and ceain types of anemia. This medicine is an antineoplastic (cancer medicine) . Mechanism of Action: Inhibits DNA methyltransferase, causing hypomethylation of DNA & cellular differentiation or apoptosis Pharmacokinetics Protein Bound: <1% Vd: 63-89 L/m2 Half-life: 30-35 min REFERENCE : www.mayoclinic.org , www.medscape.com', 'role': 'assistant'}]