This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Osteochondritis and Avascular Necrosis, Subject name: Orthopaedics
[{'content': 'Which of the following statements about changes in aicular cailage with ageing is not true: \nSelect and explain. \nA. Total proteoglycan content is decreased, B. Synthesis of proteogycans is decreased, C. Enzymatic degradation of proteoglycans is increased, D. Total water content of cailage is decreased', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Cailage propey Aging Osteoahritis Hydration Decreased Increased ( in late OA its also decreased) Proteolytic enzymes Normal Increased Proteoglycan content Decreased(due to decreased synthesis) Decreased (due to increased destruction)', 'role': 'assistant'}]