This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunology and Rheumatology, Subject name: Medicine
[{'content': 'Amyloidosis deposition most commonly occurs in: \nSelect and explain. \nA. Renal vessels, B. Knee joints, C. Skin, D. Cornea', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. A. Renal vessels* Amyloid is abnormal pathological protein resulting from improper folding of proteins and deposited extracellularly as fibrils and disrupt their normal function.* The most common site of deposition is kidney, followed by, liver, spleen, lymph nodes, adrenals, thyroid, GIT, heart etc.* In systemic amyloidosis, any organ can show deposition of Amyloid. Among all organs, kidneys are most commonly and most seriously get affected by Amyloidosis.', 'role': 'assistant'}]