This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Which among the following is NOT a coenzyme of pyruvate dehydrogenase during the decarboxylation of pyruvate? \nSelect and explain. \nA. FAD, B. NAD, C. Folic acid, D. Lipoate', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Pyruvate is oxidatively decarboxylated by pyruvate dehydrogenase (PDH) complex, producing acetyl CoA, which is the major fuel for the tricarboxylic acid cycle. This multienzyme complex requires five coenzymes: Thiamine pyrophosphate Lipoic acid FAD NAD+ Coenzyme A Pyruvate dehydrogenase is inhibited by its products, acetyl-CoA, and NADH Ref: Biochemistry By Richard A. Harvey (Ph. D.), Richard A. Harvey, Denise R. Ferrier, 2011, Page 114.', 'role': 'assistant'}]