This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Mood Disorders, Subject name: Psychiatry
[{'content': 'Esketamine, the drug that has been approved by FDA in 2019, has been approved for treatment of - \nSelect and explain. \nA. Depression, B. Resistant schizophrenia, C. Bipolar disorder, D. Ketamine dependence', 'role': 'user'}, {'content': "Answer: A \nExplanation: In 2019,FDA approved nasal spray of Esketamine It is an enantiomer of ketamine Given as a nasal spray under the practitioner's supervision. used for TRD(treatment resistant depression) Given with oral antidepressants.", 'role': 'assistant'}]