This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Central Nervous System, Subject name: Pathology
[{'content': 'Rosenthal fibres are: \nSelect and explain. \nA. Intranclear inclusions, B. Intracytoplasmic inclusions, C. Present extracellularly, D. Part of cell membrane', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans. (b) Intracytoplasmic inclusions(Ref: R 9th/pg 1253)Rosenthal fibers-*Brightly eosinophilic structures/inclusions within cytoplasm of Q astrocytic processes*Contain two heat-shock proteins (aB-crystallin and hsp27) as well as ubiquitin Q*Seen in Alexander disease, pilocytic astrocytoma Q.', 'role': 'assistant'}]