This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'All of the following can cause megakaryocytic thrombocytopenia, except - \nSelect and explain. \nA. Idiopathic thrombocytopenic purpura, B. Systemic lupus erythematosus, C. Aplastic anemia, D. Disseminated intravascular coagulation (DIC)', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Megakaryocyte is a precursor of the platelet.\nIt is increased in those cases of thrombocytopenia where thrombocytopenia is caused by the peripheral destruction of platelets.\nThere is a compensatory increase in megakaryocyte production in the bone marrow in these cases.\nThis type of thrombocytopenia is called megakaryocytic thrombocytopenia.\nOn the other hand, if thrombocytopenia occurs due to any defect in the bone marrow itself, a compensatory increase in megakaryocytes will not occur.\nThis type of thrombocytopenia is called amegakaryocytic or hypoplastic thrombocytopenia.\nIn aplastic anemia, thrombocytopenia occurs due to decreased production of thrombocytes in the bone marrow itself. So in these cases, compensatory increase in megakaryocytes will not occur.', 'role': 'assistant'}]