This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Bilirubin Metabolism, Subject name: Pathology
[{'content': 'Primary biliary cirrhosis is most commonly associated with______ \nSelect and explain. \nA. Systemic sclerosis, B. Sjogren syndrome, C. Ulcerative colitis, D. Pancreatitis', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Primary Biliary Cirrhosis Autoimmune disorder Clinical manifestation - obstructive jaundice F > M Antibody seen in antimitochondrial ab which is formed against E2 subunit of PDH enzyme. Interlobular bile ducts are actively destroyed by lymphoplasmacytic inflammation with or without granulomas.', 'role': 'assistant'}]