This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Massive splenomegaly is not seen in: September 2008 \nSelect and explain. \nA. Malaria, B. Chronic myelogenous leukemia, C. Syphilis, D. Sickle cell anemia', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans. D: Sickle cell anemiaThe causes of massive splenomegaly include:ThalassemiaVisceral leishmaniasis (Kala Azar)SchistosomiasisChronic myelogenous leukemiaChronic lymphocytic leukemiaLymphomasHairy cell leukemiaMyelofibrosisPolycythemia veraGauchers diseaseNiemann Pick diseaseSarcoidosisAutoimmune hemolytic anemiaMalariaSyphilis may show splenomegalySplenic insufficiency due to splenectomy/autoinfarction is seen in sickle cell disease.', 'role': 'assistant'}]