This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Four Formulas, Subject name: Biochemistry
[{'content': 'The enzyme activated with low Insulin : Glucagon ratio is? \nSelect and explain. \nA. Glucose 6-phosphate dehydrogenase, B. Glucokinase, C. Pyruvate kinase, D. Glucose - 6 - Phosphatase', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Insulin is released in Fed state. Low Insulin:Glucagon ratio means =Catabolic state (As low insulin means Fasting state or catabolic state) Insulin activates all anabolic enzymes with exception that it also promotes catabolic pathways glycolysis and link reaction. Enzmes Pathway Fed state activity Fasting state activity Glucokinase Glycolysis Increased Low Pyruvate Kinase Glycolysis Increased Low Glucose 6-phosphate dehydrogenase HMP Increased Low Glucose 6 Phosphatase Gluconeogenesis Low Increased', 'role': 'assistant'}]