This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
[{'content': 'Grave’s disease; all are true except: \nSelect and explain. \nA. Cardiac failure is common, B. Hypertrophy and hyperplasia or thyroid gland is due to TSH-Rab, C. Remissions and exacerbations are not infrequent, D. It is highly vascular with audible bruit', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Clinical Features\n\nHyperthyroid symptoms (heat intolerance, increased sweating and thirst, weight loss despite adequate caloric intake)\nSymptoms of adrenergic stimulation (palpitations, nervousness, fatigue,\xa0emotional liability, hyperkinesis and tremors)\nMost common\xa0GI symptom is increased frequency of bowel movements and diarrhea.\n\t\nFemale patients often develop amenorrhea, decreased fertility and increased incidence of miscarriage.\nChildren experience rapid growth with early bone maturation.\nOlder patients present with CVS complications (AF and CHF).\nOvert cardiac failure occurs in only 6-19%, increases with age\n\n\nWeight loss, facial flushing, warm and moist skin, tachycardia, cutaneous vasodilatation, collapsing pulse is seen on examination.\nA fine tremor, muscle wasting and proximal muscle group weakness with hyperactive tendon reflexes often are present.\n\t\nOverlying bruit or thrill at upper pole due to increased vascularity.\nLoud venous hum in supraclavicular space.\nOphthalmopathy (orbital proptosis) occurs in 50%, dermopathy in 1-2%.\nDermopathy\xa0is characterized by deposition of glycosaminoglycans, leading to thickened skin in pretibial region\xa0and dorsum of foot (pretibial myxedema)', 'role': 'assistant'}]