This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Increased IgA deposits are seen in - \nSelect and explain. \nA. Henoch Schonlein Purpura, B. Minimal Change Glomerulonephritis, C. Chronic Pyelonephritis, D. Haemolytic Uraemic Syndrome', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Henoch schonlein purpura \n\nThis syndrome consists of\n\n\nPruritic skin lesions characteristically involving the extensor surfaces of arms and legs as well as buttocks.\nAbdominal manifestations → Pain, vomiting, bleeding\nNonnzigratory arthralgia\nRenal abnormalities\n\n\nThe disease most commonly affects children between 3 to 8 years.\n\nRenal manifestations\n\nGross or microscopic hematuria\nProteinuria\nNephrotic syndrome\nThere is deposition of IgA, sometimes with IgG and C3, in the mesangial region.\nIgA is deposited in the glomerular mesangium in a distribution similar to that of IgA nephropathy. This has led to the concept that IgA nephropathy and Henoch-Schonlein purpura are spectra of the same disease.', 'role': 'assistant'}]