This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'All of the following are recommendations for screening of lynch syndrome in women with endometrial cancer except \nSelect and explain. \nA. Evidence of microsatellety instability, B. DNA mismatch repair protein loss, C. Endometrial cancer before 60 years of age, D. 1st or 2nd degree relative with known DNA mismatch repair gene mutation', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Lynch syndrome Genetic Screening Recommendations\nPatients with endometrial or colorectal cancer and tumor evidence of:\nMicrosatellite instability or\xa0\nDNA mismatch repair protein loss\nFisrt-degree relative with endometrial or colorectal cancer who was diagnosed:\nBefore age 60 years or\xa0\nIs at risk for Lynch syndrome based on personal and medical history.\nFirst- or second-degree relative with a known DNA mismatch repair gene mutation.', 'role': 'assistant'}]