This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pharmacology
[{'content': '2nd generation sulfonylurea drugs are all except \nSelect and explain. \nA. Glipizide, B. Gliclazide, C. Tolbutamide, D. Glibenclamide', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Tolbutamide and chlorpropamide, acetohexamide are first generation sulphonylureas- cause severe hypoglycemiA 2nd gen- less hypoglycemia- gliclazide, glipizide, glibenclamide etc (REF.Essential of medical pharmacology K D TRIPATHI 6 Edition, Page No - 266)', 'role': 'assistant'}]