This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: PCOD, hirsutism and galactorrhea, Subject name: Gynaecology & Obstetrics
[{'content': 'Regarding PCOS and hyperinsulinaemia true statement is : \nSelect and explain. \nA. Hyperinsulinaemia is observed in about 40% to 80% of women with PCOS, B. Hyperinsulinaemia stimulates hepatic synthesis of SHBG, C. Metformin causes hypoglycaemia in normoglycaemic women, D. Metformin has many other health benefits', 'role': 'user'}, {'content': "Answer: D \nExplanation: In PCOS Hyperinsulinemia is seen in 50-70% cases of PCOS Insulin induces LH to cause thecal hyperplasia and secrete androgens Hyperandrogenism lowers the level of hepatic sex hormone binding globulin Metformin treats the root causes, rectifies endocrine and metabolic function, improves feility rate, used as insulin sensitiser It reduces insulin level, delays glucose absorption, liver production of glucose and improves peripheral resistance Metformin do not cause hypoglycemia in a normoglycemic women Ref: SHAW'S TEXTBOOK OFGYNECOLOGY;15 TH EDITION; PG NO: 370", 'role': 'assistant'}]