This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hematology, Subject name: Pharmacology
[{'content': 'Which of the following drugs is not recommended in septic shock: \nSelect and explain. \nA. Normal saline, B. Activated protein C, C. Steroids, D. Rituximab', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Essentials of medical pharmacology, seventh edition, page no 872 Answer is option 4, rituximab It is not recommended in septic shock since it will adverse the condition. The major adverse effects are chills, fever, uicarial rashes, pruritus, dyspnoea, and hypotension. Pretreatment with antihistamines dampens the reaction.', 'role': 'assistant'}]