This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Osteomalacia, Subject name: Orthopaedics
[{'content': 'All of the following are true about osteomalacia EXCEPT: \nSelect and explain. \nA. Vitamin D deficiency, B. Proximal myopathy, C. Raised serum calcium, D. Bone biopsy shows increased demineralized bone matrix', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans. (c) Raised serum calciumRef: Maheswari\'s 5th/310, 311"In osteomalacia the serum calcium level is low, the phosphates are low, and alkaline phosphatase is high."PATHOPHYSIOLOGY OF OSTEOMALACIALack of sunlight exposure, nutritional deficiency of vitamin D, malabsorption syndrome, partial gastrectomy|Failure of absorption of calcium and phosphorous (Decreased serum calcium and phosphorous)|Decreased turnover of calcium and phosphorus in bone matrix|Demineralization of bone and bony substance replaced by soft osteoid tissue|Bone pains, muscular weakness (myopathy), spontaneous fracturesNOTE: Osteoid matrix is secreted at normal rate but the mineralization is decreased (i.e. decrease in mineral apposition rate). This leads to increased osteoid maturation time.Radiological Features* Looser\'s Zone (pseudo fracture)- Are radiolucent zones at sites of stress.* Triradiate pelvis in female.', 'role': 'assistant'}]