This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Urethra & Penis, Subject name: Surgery
[{'content': "A 60-year-old male presents with hematuria, weight loss. Cystoscopy biopsy of the superficial lesion in bladder shows hyperchromatic nucleus, increased nuclear - cytoplasmic ratio, the lesion involves full thickness of epithelium but doesn't invade basement membrane. The diagnosis is: \nSelect and explain. \nA. Dysplasia, B. Metaplasia, C. Bladder carcinoma in situ, D. Micro invasion", 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans. (c) Bladder Carcinoma in situRef: Bailey 26th Edition, Page 1333* Carcinoma in situ stands when the lesion does not invade basement membrane.', 'role': 'assistant'}]