This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Neurological Disorders, Subject name: Gynaecology & Obstetrics
[{'content': 'Antenatal mother with epilepsy on phenytoin therapy must be given: \nSelect and explain. \nA. Folic acid supplementation, B. Vitamin B12 supplementation, C. Vitamin B6 supplementation, D. Vitamin A supplementation', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. (a) Folic acid supplementationRef: D. C Dutta 8th ed./ 585* Use of anti- epileptic drugs like phenytoin, valproate and even phenobarbitone has been shown in pregnancy to contribute to acquire folic acid deficiency.* If a lady is deficient in folic acid at the time of her pregnancy, then the baby most likely will born with neural tube defect.* Traditionally we study that folic acid should be taken peri-conceptionally 2 months before and 3 months later to pregnant status at dose of 400 micrograms.* However with the use of anti-epileptics drugs like phenytoin, valproate etc. the dose of folic acid needs to be supplemented at a dose of 4mg once per day.', 'role': 'assistant'}]