This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Increased level of lipoprotein(a) predisposes to \nSelect and explain. \nA. Liver cirrhosis, B. Atherosclerosis, C. Nephrotic syndrome, D. Pancreatitis', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Atherosclerosis\n\nPresence of lipoprotein (a) in blood in excessive amount increases the risk of coronary heart disease.\nThis could possibly be due to the structural resemblance of this apolipoprotein with plasminogen.\nBecause of close structural resemblance, LP(a) competes with plasminogen, thereby decreasing its conversion to plasmin.\nReduced plasmin activity results in decreased dissolution of clots. This, in turn, increases the susceptibility of an individual to atherosclerosis.', 'role': 'assistant'}]