This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'Liddle syndrome is characterized by \nSelect and explain. \nA. Hypokalemic metabolic alkalosis with hypotension, B. Hypokalemic metabolic alkalosis with hypertension, C. Hyperkalemic metabolic acidosis with hypotension, D. Hyperkalemic metabolic acidosis with hypertension', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Liddle syndrome is an autosomal dominant disorder\xa0 with genetic defect(gain of function mutation) in collecting tubules sodium channel, resulting in increased tubular sodium reabsorption.', 'role': 'assistant'}]