This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Ovaries & prostate gland, Subject name: Pathology
[{'content': 'NKX3-1 immunohistochemical used for diagnosis of? \nSelect and explain. \nA. Colorectal carcinoma, B. Pancreatic carcinoma, C. Prostate, D. Renal cell carcinoma', 'role': 'user'}, {'content': 'Answer: C \nExplanation: NKX3-1 expression acts as a transcription factor that has been found to play a main role in prostate development and tumor suppression. The loss of NKX3-1 expression is frequently observed in prostate. Other markers for prostate cancer are:- PSA(prostate specific antigen) AMACR Urinary PCA 3 TMPRSS2', 'role': 'assistant'}]