This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of nucleic acids, Subject name: Biochemistry
[{'content': 'True about silent mutation in gene \nSelect and explain. \nA. No change in mRNA, B. No change in Amino acid sequence in protein, C. No expression of protein, D. No change in expression of protein', 'role': 'user'}, {'content': 'Answer: B \nExplanation: a point mutation may change the codon for one amino acid to a synonym for the same amino acid Thus the mutation is silent and has no effect on the phenotype For example CUA is mutated to CUC both code for leucine and so this mutation has no effectRef: DM Vasudevan, 7th edition, page no: 613', 'role': 'assistant'}]