This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Medicine
[{'content': 'The most reliable indicator of recent Hepatitls-B infection in a convalescing patient is - \nSelect and explain. \nA. IgM Anti HBc, B. IgM Anti F-IBe, C. HBsAg, D. IgGAntiHBs', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Hepatitis B core antigen Hepatitis B core antigen (HBcAg) is not found in the blood, but antibody to it (anti-HBc) appears early in the illness and rapidly reaches a high titre, which subsides gradually but then persists. Anti-HBc is initially of IgM type, with IgG antibody appearing later. Anti-HBc (IgM) can sometimes reveal an acute HBV infection when the HBsAg has disappeared and before anti-HBs has developed Ref Davidson edition23rd pg874', 'role': 'assistant'}]