This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'IgA nephropathy can occur in - \nSelect and explain. \nA. Membranoproliferative GN, B. Minimal change GN, C. Mesangioproliferative GN, D. RPGN type I', 'role': 'user'}, {'content': "Answer: C \nExplanation: Mesangial proliferative glomerulonephritis -\n\nIt is characterized by the proliferation of mesangial cells\nIt is classified according to the predominant type of immunoglobulin present in the glomerulus.\n\n(a) IgG in the mesangium -\n\nIncreased no. of mesangial cells in the glomeruli\nImmunoflorescence shows the presence of IgG and C3 in the mesangium.\n\n(b) IgA in the mesangium (IgA nephropathy or Berger's disease)\n\nIt is characterized by focal segmental or diffuse proliferation of mesangium.\nImmunoflorescence shows the presence of IgA deposits in the mesangium C3 is also present.", 'role': 'assistant'}]