This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous (Bio-Chemistry), Subject name: Biochemistry
[{'content': 'Metabolic alkalosis is caused by \nSelect and explain. \nA. Repeated vomiting, B. Diarrhea, C. Diabetic ketosis, D. All', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans: a (Repeated vomiting)Ref: Vasudevan & Sreekumari, 6th edi., Pg. 351METABOLIC ALKALOSISPrimary changeExcess of bicarbonate Bicarbonate level >33 mmol/L pH increased > 7.42Secondary change Increase in PaC02 (compensation)CAUSES OF METABOLIC ALKALOSISChloride responsiveProlonged vomiting,Nasogastric suctionChloride resistantMineralocorticoid excessPrimary secondary hyperaldosteronismUpper GI obstructionGlucocorticoid excessBarter's syndromeCushing's syndrome,Adrenal tumourLoop diuretics - blocks reabsorption of sodium, potassium and chlorideExogenous bases - intravenous bicarbonate, massive blood transfusion, antacids, milk alkali syndrome, and sodium citrate overload.", 'role': 'assistant'}]