This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous (Bio-Chemistry), Subject name: Biochemistry
[{'content': 'Enzyme deficiency in Acute intermittent porphyria is \nSelect and explain. \nA. ALA synthase, B. Uroporphyrinogen I- synthase, C. Uroporphyrinogen III synthase, D. Uroporphyrinogen decarboxylase', 'role': 'user'}, {'content': "Answer: B \nExplanation: B. i.e. (Uroporphyrinogen- I synthase) (286 - Harper 27th)Enzyme involvedPorphyria* ALA synthase* Uroporphyrinogen I synthase- X- linked sideroblastic anemia- Acute Intermittent porphyria* Uroporphyrinogen III synthase- Congenital erythropoietic porphyria* Uroporphyrinogen decarboxylase- Porphyria cutanea tarda* ALA synthase is the rate controlling step in hepatic porphyrin biosynthesis*** Porphyrins are synthesized mainly in Liver and bone marrow*** The conversion of uroporphyrinogen III to coproporphyrinogen III is an example of - Decarboxylation*** Prophobilinogen in urine produces pink colour with Ehrlich's aldehyde reagent**", 'role': 'assistant'}]