This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Sympathetic System, Subject name: Pharmacology
[{'content': 'Alkalinization of urine is required to treat toxicity of all except: \nSelect and explain. \nA. Salicylates, B. Barbiturates, C. Amphetamine, D. Methotrexate', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Changes in urinary pH affect tubular reabsorption of drugs that are paially ionized - * Weak bases are ionize more and are less reabsorbed in acidic urine.* Weak acids ionize more and are less reabsorbed in alkaline urine. Urine is alkalinized in barbiturate, methotrexate and salicylate poisoning.', 'role': 'assistant'}]