This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Protozoa, Subject name: Microbiology
[{'content': 'Primary amoebic encephalitis is caused by: \nSelect and explain. \nA. Nageleria fowleri, B. Acanthameba spp., C. Entamoeba hartmanni, D. Balmuthia mandrillaris', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ref: Parija SC. Textbook of Medical Parasitology. 2nd Ed. London: John Wiley & Sons; 2004.Explanation:Naeglaria fowleri causes Primary Amebic Meni ngoenceph alitis (PAM).Infection is acquired by swimming or diving in warm water contaminated with trophozoite and cysts.The trophozoites are neurotrophic - It ingests RBCs and brain tissue by phagocytosis - Production of amoebostome with cvtopathic enzymes - Acute hemorrhagic meningoencephalitis.Primary Amoebic MeningoencephalitisPAM mimics acute bacterial meningitisAbrupt in onset with acute fulminant courseCondition mostly fatal', 'role': 'assistant'}]