This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Pharmacology
[{'content': 'Mechanism of action of metoclopramide: \nSelect and explain. \nA. Increase the lower esophageal sphincter, B. Decrease the acid secretion, C. Increase gastric peristalsis, D. Ulcer healing agent', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. A. Increase the lower esophageal sphincterMetoclopramide is prokinetic drug. It acts on D2 and 5Ht3 receptor. There is increase in acetylcholine level and there is increase in LES and gastric motility.', 'role': 'assistant'}]