This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'During screening for cervical cancer in a community, PAP smear of a 51 year old female shows abnormal cytology. What is the best next logical procedure? \nSelect and explain. \nA. Conisation, B. Colposcopy & biopsy, C. Hysterectomy, D. HPV viral DNA testing', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Colposcopic examination of the cervix is the gold standard for assessing dysplasia, carcinoma in situ, and early invasive disease. Application of Lugol iodine can be a useful adjunct to the colposcopic examination. Normal mature squamous epithelium of the cervix and vagina contains glycogen and stains a dark brown color, whereas dysplastic cells lack glycogen and stain a light yellow color. Colposcopically directed biopsy is performed for visible abnormalities, including acetowhite change, abnormal vessels, ulceration, and papillary lesions. Ref: Reynolds R, Loar P.V., III (2010). Chapter 39. Gynecology. In Dohey G.M.(Eds), CURRENT Diagnosis & Treatment: Surgery, 13e.', 'role': 'assistant'}]