This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.V.S, Subject name: Pharmacology
[{'content': 'Mechanism of action of statins: \nSelect and explain. \nA. Inhibit HMG CoA synthase, B. Stimulate HMG CoA reductase, C. Inhibit HMG CoA reductase, D. Stimulate HMG CoA synthase', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ref: KDT 6th ed. pg. 614* HMG-CoA Reductase Inhibitors (statins): This class of compound is the most efficacious and best tolerated hypolipidaemic drugs.* MOA: Competitively inhibit conversion of HMG-CoA to mevalonate by the enzyme HMG-CoA reductase.* Drugs (Statins): Lovastatin, Simvastatin, Pravstatin, Atorvastatin, Rosuvastatin* All statins are given at night except: Rosuvastatin, Atorvastain (can be given at anytime)* Major side effects of statins: Myopathy* Most potent statin: Pitavastain', 'role': 'assistant'}]