This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General obstetrics, Subject name: Gynaecology & Obstetrics
[{'content': 'The sensitivity of uterine musculature is \nSelect and explain. \nA. Enhanced by progesterone, B. Enhanced by estrogen, C. Inhibited by estrogen, D. Enhanced by estrogen and Inhibited by progesterone', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Progesterone reduces muscle excitability by increasing calcium binding, thereby reducing free intracellular calcium. Oestrogen has the opposite effect and increases myometrial excitability.Refer page no 106 of Textbook of obstetrics, Sheila Balakrishnan, 2 nd edition.', 'role': 'assistant'}]