This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pharmacology
[{'content': 'Angiotensin conveing enzyme inhibitors when used for a long time in patients with hypeension, cause: \nSelect and explain. \nA. Rightward shift in renal pressure-natriuresis curve, B. Reduction in glomerular filtration fraction, C. Significant increase in hea rate, D. No change in compliance of large aeries', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Unlike the direct-acting smooth muscle vasodilators or adrenergic inhibitors, ACE inhibitors dilate the efferent as well as the afferent glomerular aerioles and thereby reduce glomerular hydrostatic pressure and renal filtration fraction, even though renal blood flow and glomerular filtration rate are preserved. Ref: KD Tripathi 8th ed.', 'role': 'assistant'}]