This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Scabies and other infestations, Subject name: Dental
[{'content': 'A 2-year-old born out of consanguineous marriage, had a history of the collodian membrane. He had large, thick, plate-like brown scaling generalized distribution; no erythroderma and ectropion. Which disease is it? \nSelect and explain. \nA. Ichthyosis vulgaris, B. Lamellar ichthyosis, C. X linked ichthyosis, D. Netheon syndrome', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Lamellar Ichthyosis(LI) Colloidion baby -the baby is covered by a thickened colloidion membrane. Scaling occurs over the whole body including creases and bends. Scale in LI - large, dark brown or grey and firmly adherent. Drooping of lower eyelids (ectropion), palmoplantar keratoderma & scarring alopecia seen in severe cases. ICHTHYOSIS VULGARIS X LINKED ICHTHYOSIS LAMELLAR ICHTHYOSIS AD XLR AR Def. of filaggrin Def. of steroid sulphatase enzyme Def. of transglutaminase-1 enzyme Extensors mainly involved Extensors and flexors involved Whole body involved-Colloidion membrane/ baby Netheon syndrome: Newborn have skin that is red and scaly (ichthyosiform erythroderma), and the skin may leak fluid.', 'role': 'assistant'}]