This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
[{'content': 'Insulin increases the activities of all of the following enzymes, EXCEPT: \nSelect and explain. \nA. Glucokinase, B. Pyruvate carboxylase, C. Glycogen synthase, D. Acetyl-CoA carboxylase', 'role': 'user'}, {'content': 'Answer: B \nExplanation: B i.e. Pyruvate carboxylase Insulin increases lipogenesis (i.e. FA, TG & glycerol P synthesis) and decrease lipolysis and so free fatty acid levelQ - Insulin activate acetyl CoA carboxylase (rate limiting enzyme of FA synthesis), activate lipoprotein lipase (so increasing TG synthesis) but inhibits hormone sensitive lipase.Q - Insulin decreases gluconeogenesis by inactivating pyruvate carboxylaseQ etc and increases glycolysis by inducing phosphofructokinase and pyruvate kinase enzymesQ.', 'role': 'assistant'}]