This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of protein and amino acid, Subject name: Biochemistry
[{'content': 'Bicarbonate moves out of RBC in peripheral tissues in exchange for \nSelect and explain. \nA. Na+, B. HP02 4-, C. Cl-, D. S02 4-', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Unlike carbon dioxide, bicarbonate is very soluble in the blood plasma and therefore must return thereby moving out of the red blood cell. However, as it moves across the membrane, a chloride ion is brought into the cell. This is known as the chloride shift and it takes place in order to maintain electric neutrality. Ref : Biochemistry by U. Satyanarayana 3rd edition Pgno : 197-200', 'role': 'assistant'}]