This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
[{'content': 'Contra indication for DRE \nSelect and explain. \nA. Acute anal fissure, B. Pilonidal sinus, C. Polyps, D. All of the above', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Acute anal fissure is very painful, so DRE Is contraindicated.', 'role': 'assistant'}]