This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'True about keloid: \nSelect and explain. \nA. Wide local excision is treatment of choice, B. It will have more collagen and vascularity, C. Will not spread beyond wound site, D. Elevated levels of growth factor is not seen', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ref. Sabiston Textbook of Surgery. Pg. 142\n\xa0\nKeloid\xa0 is the type of abnormal scar formation\xa0 and it is most commonly confused with hypertrophic scar .\n\nKeloid scars resemble hypertrophic scars superficially in that they are elevated boundary of the original injury or incision .\nMales and females equally prone to keloid scars ,but dark skin types ,especially african genetic origin are 15 times more prone .\nKeloid has familial tendency and it spreads beyond wound site\nSimilarity between keloid and hypertrophic scar is both involves abnormal collagen metabolism resulting in a higher than usual proportion of type 3 collagen and both associated with tissue hypoxia and sustained levels of TGF BETA 1 .\nKeloid contain thick collagen and have increased levels of epidermal hyaluronic acid, whereas hypertrophic scars have more nodular microscopic structure with fine collagen bundles and increased conc of alpha actin .\nTreatment -intralesional steriods injections .', 'role': 'assistant'}]