This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Other topics and Adverse effects, Subject name: Anatomy
[{'content': 'Carbimazole as compared to propylthiouracil: \nSelect and explain. \nA. Is less potent, B. Is shoer acting, C. Does not produce an active metabolite, D. Does not inhibit peripheral conversion of T4 to T3', 'role': 'user'}, {'content': "Answer: D \nExplanation: (Ref: KDT 6/e p250) Carbimazole Propylthiouracil Produces an active metabolite, methimazole No active metabolite Less plasma protein binding (PPB) More PPB Crosses placenta Does not cross placenta More potent Less potent Does not inhibit 5'-deiodinase Inhibits 5'-deiodinase", 'role': 'assistant'}]