This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hypeension, Arrhythmias, Dyslipidemia, Subject name: Pharmacology
[{'content': 'All of the following are centrally acting antihypeensive drugs except:- \nSelect and explain. \nA. Alpha methyl dopa, B. Clonidine, C. Guanabenz, D. Trimethoprim', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Stimulation of a2 receptors in CNS leads to decrease in sympathetic outflow Therefore, a2 agonists can decrease the sympathetic activity and are useful for the treatment of hypeension. These include: Clonidine a-methyl dopa Guanafacine Guanabenz', 'role': 'assistant'}]