This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Which of the following is not true regarding apoptosis? \nSelect and explain. \nA. Step ladder pattern on agarose gel electrophoresis, B. Apoptosis is energy independent process., C. Annexin V is a marker of apoptosis, D. Caspases are endonucleases', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Caspases are cysteinyl aspartate proteinases. They are cysteine proteases that cleave their substrates following an aspartate residue. They will activate endonucleases leading to chromatin clumping.', 'role': 'assistant'}]