This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetics And Genetic Disorders, Subject name: Pediatrics
[{'content': 'Which of the following is a Polygenic disorder: \nSelect and explain. \nA. Cystic fibrosis, B. Phenylketonuria, C. Multiple sclerosis, D. Hypertension', 'role': 'user'}, {'content': "Answer: D \nExplanation: d. Hypertension(Ref: Nelson's 20/e p 650, Ghai 8/e p 643)Polygenic disorders:Disorders caused by interactions between variant forms of genes and environmental factors.Occur when many polymorphisms, each with a modest effect and low penetrance, are co-inheritedE.g. HypertensionQ, Diabetes mellitus, Coronary Artery disease, Septal DefectsQ, Cleft lip", 'role': 'assistant'}]