This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'Which of the following is indication for using endogenous progesterone? \nSelect and explain. \nA. Contraception, B. For diagnostic of secondary amenorrhea, C. Endometrial hyperplasia, D. All of the above', 'role': 'user'}, {'content': "Answer: D \nExplanation: The two most frequent uses of progestins are for contraception, either alone or with an estrogen, and in combination with estrogen for hormone therapy of postmenopausal women. Progestins also are used diagnostically for secondary amenorrhea. Progestins are highly efficacious in decreasing the occurrence of endometrial hyperplasia and carcinoma caused by unopposed estrogens. Ref: Levin E.R., Hammes S.R. (2011). Chapter 40. Estrogens and Progestins. In L.L. Brunton, B.A. Chabner, B.C. Knollmann (Eds), Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e.", 'role': 'assistant'}]