This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': 'Drugs that can be used in kernicterus- \nSelect and explain. \nA. Barbiturates, B. Benzodiazepines, C. Phenytoin, D. Chlorpromazine', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Barbiturate Treatment of hyperbilirubinemia o The following are the treatment options for treatment of hyperbilirubinemia. A) Drugs (Pharmacological therapy) B) Phototherapy C) Exchange transfusion Pharmacological therapy Following drugs are used in hyperbilirubinemia ? 1) Barbiturates (Phenobarbitone) It is effective only if given to mother before delivery. It acts by inducing the conjugation of bilirubin --> Phenobarbitone is an enzyme inducer. 2) Metalloporphyrins (Tin-Sn & Zinc-Zn) o These compounds decrease the formation of bilirubin by inhibiting heme oxygenase. 3) Miscellaneous o Frequent milk feeding Prevents reabsorption of unconjugated bilirubin from intestine by reducing enterohepatic circulation. Charcol & agar --> These are bilirubin binding agents which prevent bilirubin reabsorption from gut.", 'role': 'assistant'}]