This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Liver & Biliary Tract, Subject name: Pathology
[{'content': 'Which among the following is not a predisposing factor for hepatocellular carcinoma? \nSelect and explain. \nA. Hepatitis B, B. Females, C. Hepatitis C, D. Afla toxins', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans: b (Females) Ref: Robbins, 7th ed, p. 924; Harrison, 16th ed, p. 535; Sabiston, 17th ed, p. 1548Hepatocellular Ca is more common in males (about 4 times). Other 3 options are definitely predisposing factors for HCCHepatocellular CaMore common in males60 - 90% asso.with cirrhosis liverRisk Factors;1. Hepatitis B& C2. Alcoholic liver disease3. Food contamination (Aflatoxins)4. Tyrosinaemia5. Hereditary hemochromatosis6. Liver diseases like primary biliary cirrhosis, a 1 antitrypsin deficiency.Fibrolamellar carcinomaFibrolamellar carcinoma is a variant of HCC, with better prognosis. It is more common in young females (equal incidence according to Robbins) and is a grossly scirrhous tumour with fibrous bands coursing through it.Tumour markers - Neurotensin B, vitamin B12 binding capacityNo association with HBV infection or cirrhosis', 'role': 'assistant'}]