This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nephrotic Syndrome, Subject name: Pathology
[{'content': 'Steroid resistant nephrotic syndrome associated with which gene? \nSelect and explain. \nA. NPHS 2, B. HOX II, C. PAX, D. ACE', 'role': 'user'}, {'content': 'Answer: A \nExplanation: 2 patterns of autosomal recessive FSGS Steroid-resistant nephrotic syndrome Congenital nephrotic syndrome NPHS 2 gene mutation NPHS 1 mutation Maps to chromosome 1q25-q31 Maps to chromosome 19q13 Encodes the protein podocin Encodes the protein nephrin', 'role': 'assistant'}]