This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Glycogen Metabolism and Glycogen Storage, Subject name: Biochemistry
[{'content': 'Muscle cannot make use of glycogen for energy because of deficiency of- \nSelect and explain. \nA. Glucokinase, B. Phosphoglucomutase, C. G-6-phosphatase, D. Muscle phosphorylase', 'role': 'user'}, {'content': "Answer: C \nExplanation: Ans. is 'c' i.e., G-6-phosphatase o Glucose-6-phosphatase is absent in muscles therefore, glucose-6-phosphate cannot be degraded to free glucose in muscles,o Moreover, glucose-6-phosphate cannot diffuse out of the muscles.o Therefore, muscle cannot provide glucose to maintain blood glucose level. Rather, muscle glycogen acts as a source of energy; the glucose-6-phosphate enters the glycolysis to produce energy.Difference between muscle and liver glycogenolysisMuscleLivero Little glucose is formed, since glucose-6-phosphatase is absento Free glucose forms by glucose-6-phosphataseo Stimulated by adrenaline, glucagon has no effecto Glucagon is major stimulator of glycogenolysiso Stimulated by AMP but inhibited by glucose-6-phosphateo No effect of AMP, but hepatic glycogen phosphorylase is inhibited by glucose", 'role': 'assistant'}]