This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: A.N.S., Subject name: Pharmacology
[{'content': 'Beta-adrenoceptor blocking agent that should be avoided in patients with renal failure is: \nSelect and explain. \nA. Atenolol, B. Metoprolol, C. Propranolol, D. Esmolol', 'role': 'user'}, {'content': 'Answer: A \nExplanation: (Ref: Katzung, 14th ed. pg. 179; KDT 6th ed. pg. 140 table 10.2)Lipid insoluble b blockers: These agents are mainly excreted by kidney and are therefore contraindicated in renal failure. These have long duration of action. The drugs are:Nadolol (longest acting b blockers)SotalolAtenololAcebutololBetaxololBisoprololCelioprolol', 'role': 'assistant'}]