This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'Estrogen administration in a menopausal woman increase the: \nSelect and explain. \nA. Gonadotropin secretion, B. LDL cholesterol, C. Muscle mass, D. Bone mass', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Postmenopausal women run a high-risk fr fracture of bones due to osteoporosis. PTH and IL-1 are involved. Estrogen prevents osteoporosis by inhibiting postdoc mastic activity and inhibits release of IL-1 by monocytes.\nIncreases absorption of calcium from the gut stimulates calcitonin secretion from C cells of thyroid and increases 1,25-dihydroxyvitamin D. All these lead to increased bone mineralisation', 'role': 'assistant'}]