This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Other topics and Adverse effects, Subject name: Anatomy
[{'content': '. All of the following statements about the use of spironolactone in CHF are true except \nSelect and explain. \nA. It should be administered in low doses to prevent hyperkalemial, B. It affords prognostic benefit in severe hea failure over and above that afforded by ACE inhibitors, C. It helps to overcome the refractoriness to thiazides, D. It affords rapid symptomatic relief in CHF patients', 'role': 'user'}, {'content': 'Answer: D \nExplanation: (Ref KDT 6/e p507) Loop diuretics are used to provide rapid symptomatic relief whereas aldosterone antagonists decrease the moality by reversing myocardial remodeling', 'role': 'assistant'}]