This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'AFP is raised in all except: \nSelect and explain. \nA. Polycystic kidney, B. Trisomy, C. IUD, D. Oesophageal atresia', 'role': 'user'}, {'content': 'Answer: B \nExplanation: As we have discussed earlier – AFP levels are raised in :\n\nUnder estimated gestational age\nDecreased liqour\nDecreased birth weight of infant and decreased maternal weight\nIUD\nMultifetal pregnancy (The amount of AFP entering the maternal circulation is proportional to the number of fetuses).\nDefects which permit more release of AFP into maternal serum\n\n– Neural tube defects\n– Abdominal wall defects :\n\nomphalocele\ngastroschisis\n\n– Pilonidal cysts\n– Congenital skin defects\n\nMaternal causes:\n\n– Preeclampsia\n– Maternal hepatoma, teratoma, endodermal sinus tumor\nShaw 14/e, p 380\n\nPlacental causes:\n\n– Chorioangioma of placenta\n– Placenta accreta\n– Abruptio placentae', 'role': 'assistant'}]