This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
[{'content': 'In which of the following condition is SHBG synthesis decreased? \nSelect and explain. \nA. Hypehyroidism, B. Increased estrogen, C. Increased androgen, D. Pregnancy', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Increase in androgen level is associated with decrease in SHBG synthesis. Other factors leading to decreased SHBG synthesis are: Obesity Hypothyroidism Excess glucocoicoids Also know: Factors leading to increased SHBG synthesis are: Estrogen Pregnancy Hypehyroidism Ref: Endocrine Pathophysiology, Second Edition By C. B. Niewoehner, page 285', 'role': 'assistant'}]