This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pharmacology
[{'content': 'Which of the following drugs halts macrovascular as well as microvascular effects of DM? \nSelect and explain. \nA. Acarbose, B. Biguanides, C. Meglitinide, D. Algaliptin', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., Biguanides Biguanides* Biguanides like metformin are the 1st line drugs for the treatment of Type 2 DM, which acts by AMPK activation.* Advantages of Biguanides are as followsi) Non hypoglycemic.ii) Promotes weight loss.iii) Prevents macro as well as microvascular complications of DM.iv) No acceleration of p cell failure.v) Reduction in glycosylated Hb, i.e., HbAlC by around 1%.vi) It has also found to improve fertility in PCOD patients.", 'role': 'assistant'}]