This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Urinary tract, Subject name: Pathology
[{'content': 'Foot process effacement is seen on EM in - \nSelect and explain. \nA. Minimal change disease, B. Focal segmental Glomerulosclerosis, C. IgA nephropathy, D. Mesangial proliferative GN', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Disease Pathogenesis Light Microscopy Fluorescence microscopy Electron microscopy Minimal-change disease podocyte injury Normal Negative Effacement of foot processes; no deposits Focal segmental glomerulosclerosis Unknown: reaction to the loss of renal mass. Focal and segmental sclerosis and hyalinosis Usually negative; IgM and C3 may be present in areas of scarring Effacement of foot processes; epithelial denudation Ref: ROBBINS BASIC PATHOLOGY 10th ed Pg no: 556', 'role': 'assistant'}]