This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Renal angiomyolipoma is associated with: \nSelect and explain. \nA. Tuberous sclerosis, B. Neurofibromatosis 1, C. Neurofibromatosis 2, D. All of the above', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Angiomyolipomas are present in 25% to 50% of patients with tuberous sclerosis, a disease caused by loss-of-function mutations in the TSC1 or TSC2 tumor suppressor genes. This is a benign tumor consisting of vessels, smooth muscle, and fat. It is characterized by lesions of the cerebral coex that produce epilepsy and mental retardation, a variety of skin abnormalities, and unusual benign tumors at other sites, such as the hea. Ref: Robbins 8th edition Chapter 20.', 'role': 'assistant'}]