This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Drugs, Subject name: Medicine
[{'content': 'Cardiotoxicity induced by Doxorubicin can be reduced by: \nSelect and explain. \nA. Dexrazoxane, B. Amifostine, C. Leucovorin, D. Bisphosphonates', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. A. Dexrazoxane* Cardiotoxicity induced by Doxorubicin is an important side effect which can be modified by the use of Dexrazoxane.* Dexrazoxane: Iron chelator that decreases free radical formation ~ Protects myocardium from anthracycline induced injury.* Amifostine Radio protective agent (Reduces renal toxicity caused by cisplatin) Leucovorin: Reduces bone marrow & mucosal toxicity caused by methotrexate other measures Mesna: Reduces bladder toxicity caused by Cyclophosphamide.* Bisphosphonate: Reduces bone pain & frequency of new skeletal events in metastatic breast cancer & Multiple myeloma.', 'role': 'assistant'}]