This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'Anti-CD 25 monoclonal antibody used in prophylaxis of acute organ rejection in adult patients is \nSelect and explain. \nA. Basilizimab, B. Muromonab, C. Efalizumab, D. Eculizumab', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ref. KDT. Page. 871-72\nBasiliximab exhibits high affinity towards IL-2 receptor, inhibiting it.\n\nAnti- CD-25 antibody\nHigh affinity for IL-2 receptor\nShort plasma half life - 1 week\nUseful in preventing transplant rejection reactions.\nAdverse effects - Anaphylactic reactions & opportunistic infections.\n\n\xa0\n\nMuromonab -\xa0CD3 is an immunosuppressant drug given to reduce acute rejection in patients with organ transplant\nEfalizumab - It\xa0is a monoclonal antibody that binds to CD11a, a cellsurface protein that has a key role in the pathological immune response in the skin disorder psoriasis.\nEculizumab – used in treatment of PNH', 'role': 'assistant'}]