This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Diuretics and Antidiuretics, Subject name: Pharmacology
[{'content': 'Spironolactone is contraindicated with which of the following drugs? \nSelect and explain. \nA. Enalapril, B. Atenolol, C. Verapamil, D. Chlorthiazide', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. (A) Enalapril(Ref: KDT 8/e p635)*Spironolactone is a K+ sparing diuretic. It should be used cautiously if the patient is receiving K+ salts or drugs increasing serum K+ levels.*ACE inhibitors can also cause hyperkalemia as an adverse effect. If these are combined with K+ sparing diuretics, cardiac arrhythmia due to high serum K+ levels may develop.', 'role': 'assistant'}]