This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General physiology, Subject name: Physiology
[{'content': 'Oxygen affinity decreases in \nSelect and explain. \nA. Hypoxia, B. Hypothermia, C. HbF, D. Increase in pH', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Factors that shift O2- Hb dissociation curve to right - ie. Decrease O2 affinity with Hb: |ed in H+ cone. (|pH, Bohr effect) |ed CO2 (|O2, Hypoxic condition) |ed in temperature. |ed DPG. Factors that shi O2-Hb dissocia on curve to the left side ie. increase the O2 affinity with Hb Just reverse of the right shift |in temperature (Hypothermia) |in pH (7.6) | HbF (fetal Hb) CO poisoning', 'role': 'assistant'}]