This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'All are true regarding typhoid ulcer except - \nSelect and explain. \nA. Perforation is less common in children below 5yrs, B. Placed transversely along the ileum, C. Multiple ulcer found in terminal ileum, D. Perforation occurs in 3rd week', 'role': 'user'}, {'content': "Answer: B \nExplanation: Typhoid ulcers are placed longitudinally along the ileum.\nOn the other hand. Tubercular ulcers are placed transversely along the ileum (Mnemonic: (neck) tie lies longitudinally\xa0on the body).\n\nFeatures of Typhoid ulcer -\n\nSalmonella typhi primarily affects the ileum and colon, the terminal ileum is affected most often.\nThe Peyer's patches show ovoid ulcers with their long axes along the axis of the ileum (remember that in intestinal tuberculosis, the ulcers are transverse to the axis of the bowel).\nThe margins of the ulcer are slightly raised, and the base of the ulcers is base black due to the sloughed mucosa.\nThough the enteric fever is an example of acute inflammation, neutrophils are invariably absent from cellular infiltrate and this is reflected in leucopenia with neutropenia and relative lymphocytosis in peripheral blood. The cellular infiltrates in typhoid consists of phagocytic histiocytes, lymphocytes and plasma cells.\n\nComplications of Typhoid -\n\nThe most common complications of Typhoid are perforation and haemorrhage.\nThere is never significant fibrosis in case of typhoid, hence stenosis seldom occurs in healed typhoid lesions. (strictures are common features of intestinal Tuberculosis).", 'role': 'assistant'}]