This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Dose of drug require no or minor adjustment in renal failure, except - \nSelect and explain. \nA. Doxycycline, B. Vancomycin, C. Chloramphenicol, D. Clindamycin', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., Vancomycin o Vancomycin causes renal toxicity which is dose related therefore significant dose reduction is needed in renal failure. o Rest of the drugs asked in the question are metabolised mainly in liver therefore no adjustment needed in renal failure.", 'role': 'assistant'}]