This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunity, Subject name: Pathology
[{'content': 'A 30 year old lady presents to the outpatient department with an erythematous butterfly rash on her cheeks. Which of the following antibodies should be assayed initially for her suspected condition: \nSelect and explain. \nA. Anti-ds-DNA, B. Anti-Ro-Antibody, C. Anti-Centromere-Antibody, D. Anti-mitochondrial-Antibody', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. (a) Anti-ds-DNA(Ref: Robbins 9th/pg 218-221)The given clinical features are suggestive of SLE;Specific test for diagnosis of SLE is anti ds DNA;This antibody also correlates with disease activity, nephritis, vasculitis.So Anti-dsDNA should be initially assayed in this case.', 'role': 'assistant'}]