This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'Hypercoagulation in Nephrotic syndrome is caused by: \nSelect and explain. \nA. Loss of Antithrombin III, B. Decreased Fibrinogen, C. Decreased Metabolism of Vitamin K, D. Increase in protein C', 'role': 'user'}, {'content': "Answer: A \nExplanation: Answer is A (Loss of Antithrombin III) Loss of Antithrombin III contributes to the hypercoagulable state in Nephrotic syndrome `A hypercoagulable state frequently accompanies severe nephrotic syndrome due to urinary losses of antithrmbin reduced serum levels of protein C and S, hyperfibrinogenemia and enhanced platelet aggregation'", 'role': 'assistant'}]