This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'The most significant adverse effect of ACE inhibition is - \nSelect and explain. \nA. Hypotension, B. Hypeension, C. Hypocalcemia, D. Hypercalcemia rate', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e. Hypotension First dose hypotension is a significant adverse effect of ACE inhibitor", 'role': 'assistant'}]