This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
[{'content': 'False statement about diffuse carcinoma of the stomach is: \nSelect and explain. \nA. It is seen mostly in older individuals, B. Leather Bottle appearance, C. Loss of expression of E-cadherin, D. Poorer prognosis', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Gastric adenocarcinomas divided into two categories: Diffuse type It Infiltrate and thicken the stomach wall without forming a discrete mass In younger patients Linitis plastica, or "leather bottle" appearance Loss of expression of E-cadherin Carry a poorer prognosis Intestinal type Frequently ulcerative Commonly appear in the antrum and lesser curvature Precancerous process, often initiated by Helicobacter pylori infection Ref: Harrison,E-18,P-765', 'role': 'assistant'}]