This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'The bacterial drug resistance in tuberculosis results from : \nSelect and explain. \nA. Transduction, B. Transformation, C. Plasmid mediated, D. Mutation', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Resistance to INH occurs due to point mutation in inhA or katG genes.\nResistance to rifampicin occurs due to point mutation in rpoB genes.\nResistance to ethambutol is due to mutations resulting in overexpression of the embB gene.', 'role': 'assistant'}]