This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolic Bone Disease, Subject name: Orthopaedics
[{'content': 'Most commonly involved joint in gout is - \nSelect and explain. \nA. Knee, B. Metatarsophalangeal joint of big toe, C. Wrist, D. Metacarpophalangeal joint of thumb', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., Metatarsophalangeal joint of big toe * Gout is the common end point of a group of disorders that produce hyperuricemia. It is marked by transient attacks of acute arthritis intitiated by crystallization of monosodium urate into the joints, leading eventually to chronic gouty arthritis and deposition of masses of urates in joints and other sites, creating tophi. Most common joint involved in gout is big toe, i.e. metatarsophalangeal joint of great toe.", 'role': 'assistant'}]