This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Central Nervous system, Subject name: Pharmacology
[{'content': 'Which of the following opioids should not be used with MAO inhibitors? \nSelect and explain. \nA. Morphine, B. Pentazocine, C. Buprenorphine, D. Pethidine', 'role': 'user'}, {'content': 'Answer: D \nExplanation: pethidine Nonselective MAO inhibitors interfere with hydrolysis but not with demethylation of pethidine - norepithidine is produced in excess and excitement occurs. Excitatory effects include trmors, mydriasis, hyperreflexia, delirium, myoclonus, convulsions etc. Ref: KD Tripathi 8th ed.', 'role': 'assistant'}]