This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Lysosomal Storage Diseases, Subject name: Pediatrics
[{'content': 'Bone marrow examination of a 2 year old child with massive splenomegaly and pancytopenia showed cells with wrinkled paper appearance of cytoplasm. What could be the possible diagnosis? \nSelect and explain. \nA. Niemann Pick disease, B. Gaucher disease, C. Acute Leukemia, D. Hereditary spherocytosis', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Given scenario suggests Gaucher disease Gaucher disease is the most common lysosomal storage disorder with a defect of lysosomal enzyme acid b glucosidase. Gaucher cells are lipid laden macrophages that show a characteristic histologic appearance of "wrinkled tissue paper" of cytoplasm.', 'role': 'assistant'}]