This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
[{'content': 'The immediate type of hypersensitivity in which histamine does not play a major role is: \nSelect and explain. \nA. Urticaria, B. Asthma, C. Anaphylaxis, D. Arthus reaction', 'role': 'user'}, {'content': 'Answer: D \nExplanation: None', 'role': 'assistant'}]