This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy, Subject name: Pharmacology
[{'content': 'Viral HIV integrase inhibitor is: \nSelect and explain. \nA. Zidovudine, B. Maroviroc, C. Raltegravir, D. Enfuviide', 'role': 'user'}, {'content': 'Answer: C \nExplanation: INTEGRASE INHIBITOR: RALTEGRAVIR: The HIV proviral DNA transcripted in the cytoplasm of host cell translocates to the nucleus along with an integrase enzyme. The HIV integrase nicks host chromosomal DNA and integrates the proviral DNA with it.Raltegravir is an orally active drug that blocks this step by inhibiting the integrase enzyme.it is active against both HIV-1 and HIV-2. ESSENTIALS OF MEDICAL PHARMACOLOGY K.D.TRIPATHI SEVENTH EDITION PAGE NO:811', 'role': 'assistant'}]