This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'The complications of Down syndrome include: \nSelect and explain. \nA. VSD, B. ALL, C. Hypothyroidism, D. All of the above', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Complications of Down syndrome are:\xa0\n\nCongenital cardiac defects (Most common is ventricular septal defect).\xa0\nIncreased risk of leukemia particularly ALL (more commonly) and specifically the megakaryoblastic form of AML (M7-AML).\xa0\nHypothyroidism.\xa0\nReduced fertility in females (Males are totally infertile).\xa0\nIncreased risk of respiratory tract infections.', 'role': 'assistant'}]