This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cell Wall Synthesis Inhibitors, Subject name: Pharmacology
[{'content': 'All of the following anti-microbials show Concentration dependent Killing except \nSelect and explain. \nA. Amikacin, B. Metronidazole, C. Penicillin G, D. Fluoroquinolones', 'role': 'user'}, {'content': 'Answer: C \nExplanation: * Time dependent killing(TDK) : Here, the killing activity depends upon the length of time, plasma concentration is above MIC. It is shown by:* Beta Lactams.* Vancomycin* Concentration dependent killing(CDK) : Here, killing activity depends upon the ratio of plasma concentration to MIC.It is shown by:* Aminoglycosides.* Flouroquinolone* MetronidazoleTDK and CDK mainly apply to cidal drugs.So, Penicillin G is beta lactam and follows TDK.', 'role': 'assistant'}]