This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Structure and function of protein, Subject name: Biochemistry
[{'content': 'Number of optical isomers possible for Glucose is \nSelect and explain. \nA. 2, B. 4, C. 8, D. 16', 'role': 'user'}, {'content': "Answer: D \nExplanation: Leber van Hoft rule for the number of stereoisomers is 2n where 'n' is the number of chiral centers. In open chain of glucose, there are 4 chiral centers. Hence it is 24 =16 isomers.Glucose, with four asymmetric carbon atoms, can form 16 isomers.Sugars have large numbers of stereoisomers because they contain several asymmetric carbon atoms.Ref: Harper&;s Biochemistry; 30th edition; Chapter 15; Carbohydrates of Physiological Significance", 'role': 'assistant'}]