This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Eth-A gene mutation can lead to cross resistance of Ethionamide with: \nSelect and explain. \nA. PAS, B. Isoniazid, C. Ethambutol, D. Thioacetazone', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Eth-A gene encodes Monoxygenase enzyme that activates both Ethionamide and\xa0Thioacetazone. Therefore mutation of Eth-A gene is responsible for resistance in both Ethionamide and\xa0Thioacetazone.', 'role': 'assistant'}]