This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Which interleukin is associated with fever and inflammation? \nSelect and explain. \nA. Interleukin 1, B. Interleukin 12, C. Interleukin 5, D. Interleukin 2', 'role': 'user'}, {'content': 'Answer: A \nExplanation: IL-1 is the most important cytokine responsible for the systemic effects of inflammation.\nIL-1, IL-6, TNF α and\xa0 type 1\xa0interferons contribute to acute phase response.', 'role': 'assistant'}]