This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Which is not an example of physiological apoptosis? \nSelect and explain. \nA. Organogenesis, B. Hormonal dependent apoptosis, C. Graft versus host disease, D. Selective death of lymphocytes', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Apoptosis in Biologic Processes:\nApoptosis is responsible for mediating cell death in a wide variety of physiologic and pathologic processes as under:\nPhysiologic Processes: \n\nOrganised cell destruction in sculpting tissues during development of embryo.\nPhysiologic involution of cells in hormone-dependent tissues. E.g, endometrial shedding, regression of lactating breast after withdrawal of breast-feeding.\nNormal cell destruction followed by replacement proliferation such as in intestinal epithelium.\nInvolution of the thymus in early age.\n\nPathologic Processes: \n\nCell death in tumors exposed to chemotherapeutic agents.\nCell death by cytotoxic T cells in immune mechanisms such as in graft-versus-host disease and rejection reactions.\nProgressive depletion of CD4+T cells in the pathogenesis of AIDS.\nCell death in viral infections e.g, the formation of Councilman\xa0bodies in viral hepatitis.\nPathologic atrophy of organs and tissues on withdrawal of stimuli e.g.\xa0prostatic atrophy after orchiectomy, atrophy of kidney or salivary gland on obstruction of ureter or ducts, respectively.\nCell death in response to injurious agents involved in causation of necrosis e.g. radiation, hypoxia and mild thermal injury.\nIn degenerative diseases of CNS e.g.\xa0in\xa0Alzheimer’s disease, Parkinson’s disease, and chronic infective dementias.\nHeart diseases e.g. heart failure, acute myocardial infarction (20% necrosis and 80% apoptosis).\n\nHarshmohan - Essential Pathology for Dental Students Ed 4th P: 40,41', 'role': 'assistant'}]