This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: NEET 2019, Subject name: Pathology
[{'content': 'Caspase involved in activation of IL_1 is which of the following? \nSelect and explain. \nA. Caspase 1, B. Caspase 3, C. Caspase 5, D. Caspase 8', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Pyroptosis :- Example of process in which injury is initiated because of exposure to microbes. Whenever there is exposure to microbes there is activation of enzyme caspase 1 and caspase 11. Caspase 1 conve inactive form of IL 1 to active form of IL1. As IL1 has central action, it enters CNS and results in development of fever. Caspase-1 along with closely related caspase-11 also cause death of the infected cell. -Caspase 3, a typical executioner caspase that cleaves DNA and other substrates to cause cell death.', 'role': 'assistant'}]