This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': "True about Wilson's disease \nSelect and explain. \nA. Increase in urinary copper and increased serum ceruloplasmin and copper, B. Increased serum ceruloplasmin levels with increased urinary copper, C. Elevated hepatic copper level and increased serum ceruloplasmin levels, D. Increased in urinary copper and decreased serum ceruloplasmin", 'role': 'user'}, {'content': 'Answer: D \nExplanation: Wilson disease is an inborn error of metabolism due to toxic accumulation of copper in the liver, brain, cornea and other tissues.\nSerum ceruloplasmin is decreased(<20 mg/dl) and the 24-hour urinary copper excretion is more than 100 micrograms/day.\nHepatic copper values usually above 250 micrograms /gram of dry weight of liver.', 'role': 'assistant'}]