This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nephritic & Nephrotic Syndrome, Subject name: Pediatrics
[{'content': 'A 4 years old child presented with generalized edema and ascites. There was no hypeension or hematuria. Renal function tests were normal. Urinalysis revealed massive proteinuria. Most probable underlying cause is: \nSelect and explain. \nA. Membranous glomerulonephritis, B. Minimal change disease, C. Post streptococcal glomerulonephritis, D. IgA nephropathy', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Generalized edema in a child with massive proteinuria, with no hypeension or hematuria & normal renal function suggests a diagnosis of Nephrotic syndrome due to minimal change disease (also known as lipoid nephrosis or nil disease) Post streptococcal glomerulonephritis- hypeension, hematuria IgA nephropathy- hematuria, h/o UI Membranous glomerulonephritis- hypeension, hematuria', 'role': 'assistant'}]