This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Pharmacokinetics, Subject name: Pharmacology
[{'content': 'Therapeutic index is a measure of? \nSelect and explain. \nA. Efficacy, B. Adverse effects, C. Safety, D. Potency', 'role': 'user'}, {'content': "Answer: C \nExplanation: ANSWER: (C) Safety REF: KDT 7th ed p, 54/55Therapeutic index = Median lethal dose/Median effective doseOne estimate of a drug's margin of safety is the ratio LD50/ED50, the therapeutic index, which is a statement of how selective the drug is in producing its desired versus its adverse effects.", 'role': 'assistant'}]