This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: JIPMER 2017, Subject name: Pharmacology
[{'content': 'Which of the following statement is false regarding Leflunomide: \nSelect and explain. \nA. Used in treatment of Rheumatoid ahriti, B. Act by inhibiting IMP dehydrogenase enzyme, C. Inhibits proliferation of T and B cells, D. It is contraindicated in pregnancy', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Leflunomide is a prodrug of an inhibitor of pyrimidine synthesis by inhibiting enzyme dihydro orotate dehydrogenase thereby inhibiting proliferation of T and B cell. Toxicities include elevation of liver enzymes with some risk of liver damage, renal impairment, and teratogenic effects. It is approved only for rheumatoid ahritis at present, although studies are underway combining leflunomide with mycophenolate mofetil for a variety of autoimmune and inflammatory skin disorders, as well as preservation of allografts in solid organ transplantation. Mycophenolate mofetil: Act by inhibiting IMP dehydrogenase enzyme ,suppresses both B and T-lymphocyte.', 'role': 'assistant'}]