This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Medicine
[{'content': 'Which is true regarding ataxia telangiectasia: \nSelect and explain. \nA. Increase in AFP, B. Increases the risk of squamous cell carcinoma, C. Autosomal dominant, D. None of above', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Increase in alpha-fetoprotein is observed in Ataxia telangiectasia * Ataxia-telangiectasia / Ataxia-telangiectasia syndrome / Louis-Bar syndrome * Rare, neurodegenerative, autosomal recessive disorder causing severe disability. * Ataxia refers to poor coordination; Telangiectasia refers to small dilated blood vessels. * Pas affected: * Cerebellum - movement & coordination difficulties * Immune system - Predisposing to infections. * Genetic repair system - Preventing process for repairing DNA - Cancer risk * Features: * Increased incidence of lymphoma & Leukemia * Increased alpha-Fetoprotein levels * Oculomotor apraxia (difficulty in coordination between head & eye movements) * Dysahria REF: HARRISONS 21ST ED', 'role': 'assistant'}]