This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunology, Subject name: Microbiology
[{'content': 'IFN-a and IFN-b are produced by the virus-infected cell due to the interaction of virus nucleic acid with which of the following? \nSelect and explain. \nA. C3 (third component of complement), B. Defensins, C. TLR pathway, D. IL-12', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Following virus entry into a cell, the virus initiates replication and the viral nucleic acid interacts with specific microbial sensors (TLR3, TLR7, TLR 9, RIG-1, and MDA-5). This interaction triggers cellular production of IFN that is secreted from the infected cell.Jawetz 27e pg: 130', 'role': 'assistant'}]