This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Radiology
[{'content': 'All are X-ray findings of retinoblastoma except : \nSelect and explain. \nA. Widening of optic canal, B. Intra cerebral calcification, C. Intraocular calcification, D. Secondaries in cranial bones', 'role': 'user'}, {'content': "Answer: B \nExplanation: B i.e. Intracerebral calcification Retinoblastoma is the malignant congenital intraocular tumor arising from primitive photoreceptor cells of retina (included in primitive neuroectodermal tumor). Histologically, it shows Flexner-Wintersteiner rosettesQ (50%) Home-Wright rosettesQ &fleurettesQ. Clinically presents with cat's eye reflex/leukokoriaQ. Retinoblastoma is the most common cause orbital calcificationQ (nodular or punctate calcification & is ourable prognostic sign.) Enlargement of orbit & orbital canalQ occurs d/t involvement of optic nerve & intracranial extension. Metastasize to meninges, cranial bonesQ, bone marrow, lung, liver, lymph node.", 'role': 'assistant'}]