This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Thyroid Tumor, Subject name: Pathology
[{'content': 'RET proto-oncogene is associated with:- \nSelect and explain. \nA. Medullary thyroid cancer, B. Paraganglioma, C. Papillary thyroid cancer, D. CNS tumors', 'role': 'user'}, {'content': 'Answer: A \nExplanation: RET proto-oncogene: Associated with development of MEN II syndrome (affects thyroid & adrenal medulla) Therefore, patients have risk of developing medullary thyroid cancer & pheochromocytoma. Thyroid tumors & associated mutations: - Papillary thyroid cancer: RET-PTC gene - Follicular thyroid cancer: RAS gene - Anaplastic thyroid cancer: p53 gene', 'role': 'assistant'}]