This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Inflammation & Repair, Subject name: Pathology
[{'content': 'Most important pyogenic Interleukin is? \nSelect and explain. \nA. IL-2, B. 1L-1, C. IL-6, D. IL-8', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans. (b) 1L-1(Ref: J Infect Dis. (1999) 179 (Supplement 2): S294-S304. doi: 10.1086/513856, Harrison 18th ed:2666)Following cytokines are intrinsically pyrogenic in that they produce a rapid-onset fever by acting directly on the hypothalamus without the requirement for the formation of another cytokine:IL-1a,TNF-a,TNF-b,IFN-a,and IL-6.PLEASE NOTE: IL-18 of IL-1 family is not pyrogenic', 'role': 'assistant'}]