This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Which is true about Multiple Myeloma? \nSelect and explain. \nA. M spike increase, B. Direct plasma cell deposition in glomerular capillaries leads to kidney damage, C. IL 8 is a marker for bone lesions, D. Invariablly increase in alkaline Phosphatase', 'role': 'user'}, {'content': 'Answer: A \nExplanation: None', 'role': 'assistant'}]