This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Surgery
[{'content': 'Most common site for bone metastasis in carcinoma of the breast in women is: \nSelect and explain. \nA. Skull, B. Ribs, C. Spine, D. Pelvis', 'role': 'user'}, {'content': 'Answer: C \nExplanation: (C) Spine > It is by this route that skeletal metastases occur, although the initial spread may be via the lymphatic system. In order of frequency the lumbar vertebrae, femur, thoracic vertebrae, rib and skull are affected and these deposits are generally osteolytic.> Metastases may also commonly occur in the liver, lungs and brain and, occasionally, the adrenal glands and ovaries; they have, in fact, been described in most body sites.', 'role': 'assistant'}]