This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
[{'content': "The following test is an example of heterophile antigen based test- \nSelect and explain. \nA. Rose-wallers test, B. Widal's test, C. Brucella agglutination test, D. Paul Bunnel's along with HLA Class-I stimulate", 'role': 'user'}, {'content': 'Answer: D \nExplanation: In infectious mononucleosis, the patient exhibits- Atypical lymphocytes in the circulating blood. - Antibodies to the EB Virus. - Increased heterophile antibody titre. The normal titre of agglutinins and hemolysins in human blood against sheep red blood cells does not exceed 1:8, but in infectious mononucleosis the titre may rise to 1:4096. This is referred to as positive Paul Bunnel test and is both characteristic and pathognomic of the disease.', 'role': 'assistant'}]