This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetics And Genetic Disorders, Subject name: Pediatrics
[{'content': 'Risk of having a child with Down syndrome: \nSelect and explain. \nA. Is unaffected by maternal age, B. Decreases with increase in maternal age, C. Increases with increase in paternal age, D. Increases with increase in maternal age', 'role': 'user'}, {'content': "Answer: D \nExplanation: d. Increases with increase in maternal age(Ref: Nelson's 20/e p 610-614)Risk of Down Syndrome Increased with Increase in Maternal AgeMaternal ageIncidence of Down Syndrome20 years1 in 150030 years1 in 90040 years1 in 10045 years1 in 30", 'role': 'assistant'}]