This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Mediators of inflammation are all except - \nSelect and explain. \nA. TNF, B. IFN, C. Myeloperoxidase, D. Prostaglandins/Interleukins', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Mediators of inflammation:-\nThe vascular and cellular reactions of both acute and chronic inflammation\xa0are mediated by chemical factors\xa0known as a mediator of inflammation.\nMediators originate either: -\n1. From plasma\nComplement proteins, Bradykinin\n2. From cells\nCells derived mediators may be performed and are stored in secretory granules or they may be synthesized\xa0de novo in response to a stimulus.\nPreformed mediators → Histamine, Serotonin, Lysosomal enzymes.\nNewly synthesized → Prostaglandins, Leukotrienes, platelet activating factors, nitric oxide, reactive oxygen species, cytokines (TNF, IL-1).\nMyeloperoxidase is not an inflammatory\xa0mediator. It is an enzyme of neutrophil which catalyzes the conversion\xa0of Cl, Br, and T, and SCN to the corresponding acids (HOCl, HOBr etc.). These acids are potent oxidants and help\xa0in destroying the invading organisms.\nMediators of Acute inflammation', 'role': 'assistant'}]