This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Misc. (R.B.C), Subject name: Pathology
[{'content': 'Hemolytic crisis in hereditary spherocytosis is precipitated by \nSelect and explain. \nA. Parvovirus B19 infection, B. Infectious mononucleosis, C. Human T-cell leukemia virus, D. Cytomegalovirus', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. (a) Parvovirus B19 infection(Ref: Harrison 18th/pg 1478)Aplastic/hypoplastic crises resulting from parvovirus B19 infection may occur in Hereditary spherocytosis just as is seen in individuals with other chronic hemolytic disorders.Parvovirus B19 selectively infects erythroid precursors and inhibits their growth.Erythropoietic arrest leads to a sudden decrease in hemoglobin concentration and reticulocytopenia.', 'role': 'assistant'}]