This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Gastrointestinal tract, Subject name: Pharmacology
[{'content': 'metaclopromide: \nSelect and explain. \nA. inhibit cholinergic smooth.muscle stimulation in the gastrointestinal tract, B. decrease lower esophageal spinchter pressure, C. stimulate D2 receptor, D. enhance colonic activity', 'role': 'user'}, {'content': 'Answer: D \nExplanation: metaclopromide is aD2 receptor antagonist that increases cholinergic activity by inhibiting presynapyic D2 receptors in GIT . it increases LES tone that is also responsible for anti emetic action. it does not significantly increase colonic motility', 'role': 'assistant'}]