This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Pediatrics, environment and nutrition, Subject name: Pathology
[{'content': 'Which of the following trace element deficiency leads to abnormal collagen cross-linking? \nSelect and explain. \nA. Zinc, B. Flouride, C. Selenium, D. Copper', 'role': 'user'}, {'content': 'Answer: D \nExplanation: ElementFunctionBasis of DeficiencyClinical FeaturesCopperComponent of cytochrome c oxidase, dopamineb-hydroxylase, tyrosinase, lysyl oxidase, andunknown enzymes involved in cross-linking collagenInadequate supplementation inaificial dietInterference with absorptionMuscle weaknessNeurologic defectsAbnormal collagen cross-linkingRef: Robbins and Cotran Pathologic Basis of Disease; 9th edition; Chapter 9; Environmental and Nutritional Diseases; Page no: 442; Table 9-10', 'role': 'assistant'}]