This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Autacoids, Subject name: Pharmacology
[{'content': 'Rofecoxib was withdrawn due to: \nSelect and explain. \nA. lschemic hea disease, B. Renal complication, C. Liver adenoma, D. Gastric ulcer', 'role': 'user'}, {'content': 'Answer: A \nExplanation: celecoxib,etoricoxib,parecoxib are available in India.Rofecoxib and valdecoxib were withdrawn within a few years of marketing for increasing cardiovascular risk by increasing the levels of TXA2 which increases platelet aggregation ESSENTIALS OF MEDICAL PHARMACOLOGY;7TH EDITION;KD TRIPATHI;PAGE NO 205', 'role': 'assistant'}]