This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Apparant volume of distribution of a drug less than 5 liters implies that the drug is predominantly in which of the following compament? \nSelect and explain. \nA. Extracellular fluid, B. Total body water, C. Intracellular fluid, D. Intravascular fluid', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans is 'a' i.e., Extracellular fluido A drug with high volume of distribution has more concentration in tissue and less in plasma.o A drug with low volume of distribution has concentration only in plasma (intravascular)Relationship between volume of distribution and extent of distributionVd (L)% body weightExtent of distribution< 57only in plasma5-207-28In extracellular fluid20-4028-56In total body water>40>56In deep tissues; bound to peripheral tissues", 'role': 'assistant'}]