This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: miscellaneous, Subject name: Pathology
[{'content': "Which of the following is not a channelopathy?- \nSelect and explain. \nA. Cystic fibrosis, B. Liddle's syndrome, C. Tay-sachs disease, D. Hypokalemic periodic paralysis", 'role': 'user'}, {'content': 'Answer: C \nExplanation: Channelopathies are diseases caused by the disturbed function of ion channel subunits or the proteins that regulate them. Tay-Sachs disease is a GM2 gangliosidosis caused by the deficiency of enzyme hexosaminidase, subunit.', 'role': 'assistant'}]