This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti Microbial, Subject name: Pharmacology
[{'content': 'Despite its "age," penicillin G remains the drug of choice in the treatment of infections caused by \nSelect and explain. \nA. B. fragilis, B. T. pallidum, C. H. influenzae, D. E. coli', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Indications for the use of penicillin G are currently limited for a number of reasons. The drug has a narrow spectrum, is susceptible to beta-lactamases, and may cause hypersensitivity, and alternative antibiotics are available. However, penicillin G remains the drug of choice in syphilis, usually given IM as benzathine penicillin G, but as the Na or K salt IV in neurosyphilis. What would you do for patients who are highly allergic to penicillins? (Consider tetracyclines, or possibly desensitization.)', 'role': 'assistant'}]