This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Surgery
[{'content': 'The earliest symptom in primary biliary cirrhosis is \nSelect and explain. \nA. Jaundice, B. Pruritus, C. Melanosis, D. Vomiting', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Pruritis occurs because of deposition of bile salts in the skin, this clinical symptom occurs before the development of jaundice.', 'role': 'assistant'}]