This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Protein Synthesis Inhibitors, Subject name: Pharmacology
[{'content': 'What is the most serious adverse effect of streptomycin? \nSelect and explain. \nA. Hepatotoxicity, B. Ototoxicity, C. Ocular toxicity, D. Hematological disturbances', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Streptomycin (S) This is a tuberculocidal aminoglycoside. It is not absorbed orally and must be administered by IM injection. It is active only against extra-cellular bacteria. It is NOT HEPATOTOXIC. Major adverse effects are ototoxicity, nephrotoxicity and neuromuscular blockade. Streptomycin is contraindicated in PREGNANCY.', 'role': 'assistant'}]