This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: JIPMER 2017, Subject name: Pediatrics
[{'content': 'A newborn has fused eyes and single nasal chamber & undeveloped callosum. What is the most probable diagnosis? \nSelect and explain. \nA. Holoprosencephaly, B. Schizencephaly, C. Plagiocephaly, D. Brachycephaly', 'role': 'user'}, {'content': "Answer: A \nExplanation: Holoprosencephaly: brain doesn't properly divide into right and left hemispheres. Associated with trisomy 13 (MC), trisomy 18, CHARGE syndrome Schizencephaly- characterized by abnormal slits or clefts in the cerebral hemispheres of the brain. Plagiocephaly- characterized by an asymmetrical distoion (flattening of one side) of the skull. Brachycephaly- result of premature synostosis of both coronal sutures.", 'role': 'assistant'}]