This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: FMGE 2019, Subject name: Pharmacology
[{'content': 'Antidote for opioid poisoning; \nSelect and explain. \nA. Naloxone, B. Pethidine, C. Flumazenil, D. Physostigmine', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Naloxone is an opioid antagonist given intravenously. It blocks mu, kappa and delta receptors. It is the DOC for opioid toxicity. is given parenterally (ineffective orally) and is a very sho acting drug. Pethidine (Meperidine)- fully agonist at opiod receptors Flumazenil-Flumazenil is specific antidote for benzodiazepines. Physostigmine - it is a lipid soluble anticholinesterase. It is the specific antidote for poisoning with belladonna.', 'role': 'assistant'}]