This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Psychiatry
[{'content': "The patients of Down syndrome has high risk of developing  ________ in the future : \nSelect and explain. \nA. Parkinson syndrome, B. Lewy body dementia, C. Alzheimer's disease, D. Juvenile myoclonic epilepsy", 'role': 'user'}, {'content': "Answer: C \nExplanation: Patients with Down syndrome i.e 21st\xa0trisomy has highest risk for developing\xa0Alzheimer's disease as gene for APP (Amyloid precursor protein) is present on chromosome 21.", 'role': 'assistant'}]