This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: CHF, Angina Pectoris and Myocardial Infarction, Subject name: Pharmacology
[{'content': 'The most impoant channel of elimination of digoxin is: \nSelect and explain. \nA. Glomerular filtration, B. Tubular secretion, C. Hepatic metabolism, D. Excretion in bile', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Digoxin is primarily eliminated unchanged by glomerular filtration Digitoxin is eliminated by hepatic metabolism.', 'role': 'assistant'}]