This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
[{'content': "Palpable fibrous plaque on dorsal penile shaft indicates- \nSelect and explain. \nA. Paget's disease, B. Potter's syndrome, C. Prehn's sign, D. Peyronie's disease", 'role': 'user'}, {'content': 'Answer: D \nExplanation: • Peyronie’s disease (plastic induration of penis/ penile fibromatosis) usually seen over 40 years of age.\n• It is due to fibrous plaques in one or both corpus cavernosum of varying sizes involving tunica albuginea\xa0which may later calcify or ossify.\n• Cause remains obscure, the dense fibrous plaque is microscopically consistent with findings of severe vasculitis.\n• Palmar fibromatosis (Dupuytren’s contracture), plantar fibromatosis and penile fibromatosis (Peyronie’s disease) are components of the same pathological process called superficial fibromatosis.\nClinical Features\n• Painful erection, curvature of penis and poor erection distal to involved area.\n• No pain when the penis is in nonerect state.\n• Palpable induration or mass appears usually on the dorsolateral aspect\xa0of the penis.\nTreatment\n• Spontaneous remission occurs in about 50% cases, so observation and emotional support advised initially.\n• If the penile deformity is distressing, Nesbitt’s operation\xa0can be performed to straighten the penis.\n• Nesbitt operation: Straightening of penis by placing non-absorbable sutures in corpus cavernosum opposite to the plaque.', 'role': 'assistant'}]