This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Thalassemia, Subject name: Medicine
[{'content': 'In alpha-thalassemia trait, electrophoresis shows: \nSelect and explain. \nA. Increased HbF & normal HbA2, B. Normal HbF & normal HbA2, C. Normal HbF & decreased HbA2, D. Decreased HbF & normal HbA2', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Electrophoresis is a screening test for hemoglobinopathies Normal individual Sickle cell anaemia a thalassemia b thalassemia HbA 95% Absent Less HbF 2% Present Normal Increased HbA2 3% Present Normal Increased Note: In sickle cell anemia absence of HbA means the disease severity is very high. But in sickle cell trait HBA is present. Note: Screening test for both a & b thalassemia is NESTROF IOC for both a & b thalassemia is HPLC', 'role': 'assistant'}]