This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Wound Healing, Subject name: Pathology
[{'content': 'Which of the following nutritional factors is required for proper collagen assembly in the scar tissue of the 25-year-old woman who sustains a deep, open laceration over her right forearm in a motorcycle accident. \nSelect and explain. \nA. Folic acid, B. Thiamine, C. Vitamin A, D. Vitamin C', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Vitamin C (ascorbic acid) is a powerful, biologic reducing agent that is necessary for the hydroxylation of proline residues in collagen. Vitamin C deficiency (scurvy) causes formation of an abnormal collagen that lacks tensile strength. Patients with vitamin C deficiency exhibit poor wound healing. Dehiscence (bursting open) of previously healed wounds may also occur. None of the other choices are required for collagen assembly.', 'role': 'assistant'}]