This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Thyroid Tumor, Subject name: Pathology
[{'content': 'Which of the following is not a feature of Papillary carcinoma of thyroid? \nSelect and explain. \nA. Rearrangement of RET gene, B. Rearrangement of NTRK1 gene, C. Mutation of BRAF gene, D. Mutation of RAS gene', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Most papillary carcinomas have gain-of-function mutations or rearrangements involving: RET gene NTRK1 receptor tyrosine kinases Serine/threonine kinase BRAF, which is component of MAPK pathway. RAS mutations are seen in follicular carcinoma of thyroid.', 'role': 'assistant'}]