This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetics, Subject name: Pathology
[{'content': 'A 2-year-old child has been followed for mental retardation and slow development, as well as multiple bih defects. The child has a high-pitched catlike cry. On examination, microcephaly, hypeelorism, micrognathia, epicanthal folds, low-set ears, and hypotonia are noted. Karyotypic analysis would be expected to show \nSelect and explain. \nA. 5p-, B. 22q11-, C. 45,XO, D. 46,XY', 'role': 'user'}, {'content': 'Answer: A \nExplanation: The clinical presentation is that of the cri du chat (or 5p-) syndrome. Cri du chat Paial deletion of the sho arm of chromosome 5 Ho-pitched catlike cry Microcephaly, Hypeelorism, Micrognathia, Epicanthal folds, Low-set ears, Hypotonia', 'role': 'assistant'}]