This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'A man with a mass at duodenojejunal flexor invading renal papillae. Histopathology revealed it as lymphoma which of the following is true: \nSelect and explain. \nA. II E stage, B. I E Stage, C. IV E stage, D. Staging cannot be done until bone marrow examination is performed', 'role': 'user'}, {'content': 'Answer: C \nExplanation: The stages of gastrointestinal lymphomas are staged using a modified Ann Arbor classification: IE: Tumor confined to small intestine HE: Spread to regional lymph nodes HIE: Spread to non resectable nodes beyond regional nodes IVE: Spread to other organs In this patient the mass has invaded the renal papillae (spread to other organs) hence it is under stage IV E. Ref: Gastrointestinal Lymphoma: Future Perspectives By Wolfgang Fishbach, Page 75 ; Grading and Staging in Gastroenterology By G. Tytgat, Stefaan Tytgat, Pages 64-65', 'role': 'assistant'}]