This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Anatomy
[{'content': 'The presence of the philadephia chromosome is associated with a worse prognosis in patients with which of the following diseases? \nSelect and explain. \nA. Acute lymphoblastic leukemia, B. Acute myelogenous leukemia, C. Chronic lymphocytic leukemia, D. Chronic myelogenous leukemia', 'role': 'user'}, {'content': 'Answer: A \nExplanation: The presence of the philadelphia chromosome a translocation from the long arm of chromosome 22 to chromosome 9 (t,9,22) is associated with a more ourable prognosis in patients with chronic myelogenous leukemia but is associated with an unourable outcome in Acute lymphoblastic leukemia. (ref Robbins 8th/603)', 'role': 'assistant'}]