This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Antiplatelets and Fibrinolytics, Subject name: Pharmacology
[{'content': 'Alteplase differs from streptokinase as it: \nSelect and explain. \nA. Is longer acting, B. Is derived from human kidney, C. Is cheap, D. Activates plasminogen bound to fibrin', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans. (D) Activates plasminogen bound to fibrin(Ref: KDT 8/e p674)Fibrinolytics are the drugs which activate plasminogen to form plasmin and thus help in lysis of thrombus. These drugs can cause bleeding as the major adverse effect due to lysis of physiological thrombi as well as due to excessive amount of plasmin generated in the circulation.', 'role': 'assistant'}]