This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Most potent stimulator of naive T cell is? \nSelect and explain. \nA. Mature dendritic cell, B. Follicular dendritic cell, C. Macrophages, D. B cell', 'role': 'user'}, {'content': 'Answer: A \nExplanation: There are 2 types of dendritic cells:Interdigitating dendritic cells and Follicular dendritic cells. Interdigitating dendritic cells - These are the most potent antigen presenting cells for T cells. These are present in the lymphoid tissues & non lymphoid organs. Immature dendritic cells present in the skin are called as Langerhans cells. They are non phagocytic & express high levels of MHC -II molecules & B7-1, B7-2. Follicular dendritic cells -Theses are present in germinal centers of lymphoid follicles. These can bind to antigen bound to antibody & present it to B cell. Ref: Robbins 8th Ed Pg 187.', 'role': 'assistant'}]