This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'The action of non-competitive muscle blockers is affected by - \nSelect and explain. \nA. Hypocalcemia, B. Hyponatremia, C. Hypehermia, D. All of the above', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Hypocalcemia Hypocalcemia has following effects It decreases vesicular ACh release at neuromuscular junction. It causes uncoupling of excitation and contraction. o By action 1. it will enhance the effect of both competitive as well as noncompetitive blockers due to unavailibility of ACh. o By action 2. it will enhance the effect of directly acting muscle relaxant (dantroline).", 'role': 'assistant'}]