This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Gene for Wilms tumor is located on- \nSelect and explain. \nA. Chromosome 11, B. Chromosome 1, C. Chromosome10, D. Chromosome12', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Mutations of the WT1 gene on chromosome 11p13 are observed in approximately 20% of Wilms\xa0tumors.\nAt least half of the Wilms tumors with mutations in WT1 also carry mutations in CTNNB1, the gene encoding the proto-oncogene beta-catenin.', 'role': 'assistant'}]