This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Which of he following enzyme is involved in the catabolism of fructose to pyruvate in the liver? \nSelect and explain. \nA. Glucokinase, B. Phosphoglucomutase, C. Lactate-dehydrogenase, D. Glyceraldehyde-3-phosphate Dehydrogenase', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Fructose is a ketohexose presents in fruits, honey, and sucrose. Fructose is promptly metabolized by the liver. Fructose is phosphorylated by fructokinase, an enzyme present in the liver with a high affinity for fructose to Fructose-1-phosphate. Then Fructose-1-phosphate is then cleaved to Glyceraldehyde by aldolase-B. The Glyceraldehyde is phosphorylated to Glyceraldehyde-3-phosphate by triose kinase and ATP. Glyceraldehyde-3-phosphate + dihydroxyacetone gives 1,3 bisphosphoglycerate catalysed by Glyceraldehyde-3-phosphate Dehydrogenase. This 1,3 bisphosphoglycerate is finally metabolized into pyruvate. Ref: Vasudevan Biochemistry, 4th Edition, Pages 88, 119-120', 'role': 'assistant'}]