This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Not gluconeogenic? \nSelect and explain. \nA. Acetyl CoA, B. Lactate, C. Glycerol, D. Alanine', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. is \'a\' i.e., Acetyl CoA Substrates for gluconeogenesis are lactate (lactic acid), pyruvate, glycerol, glucogenic amino acids (all amino acids except leucine and lycine), propionate and intermediates of citric acid cycle.Acetyl CoA canot be conveed into glucose. This is because the reactionPyruvate Acetyl-CoA" is irreversible.Pyruvate carboxylasePyruvate is the staing substrate for gluconeogenesis (Pyravate_ Oxaloacetate). As acetyl CoA cannot be conveed into pyruvate, it is not a substrate for gluconeogenesis.', 'role': 'assistant'}]