This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'True about Yolk sac tumour : \nSelect and explain. \nA. Also called endodermal sinus tumour, B. Always have elevated AFP level, C. Schiller Duval bodies seen and Highly malignant both, D. All', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans. is a, b and c i.e. Also called endodermal sinus tumour; Always have elevated AFP level ; Schiller Duval bodies seen; and Highly malignant Endodermal sinus tumour : Endodermal sinus (yolk sac) tumour is second most common malignant germ cell tumour of ovary affecting mostly children or young women. (Age group 14 - 20 years. Tumour is highly malignant and is most rapidly growing tumour of whole body. . Histologically the pathognomic finding is Schiller - Duval bodiesdeg which is a single papilla lined by tumour cells with a central blood vessel. Due to high rate of growth, tumour usually presents with acute abdomen. Mostly unilateral - other ovary is involved with metastatic disease only when there are other metastasis in peritoneal cavity. Almost all cases are associated with raised AFP and Alpha 1 antitrypsin. It is the most deadly malignant ovarian germ cell tumor. Treatment : Chemotherapy. It has a high propensity for rapid growth, peritoneal spread and distant hematogenous dissemination to the lungs. Highly malignant', 'role': 'assistant'}]