This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Joint disorders, Subject name: Orthopaedics
[{'content': 'All are Characteristic of SAPHO syndrome except \nSelect and explain. \nA. Synovitis, B. Acne, C. Pustulosis, D. Hyperpigmentation', 'role': 'user'}, {'content': 'Answer: D \nExplanation: The syndrome of synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) characterized by a variety of skin and musculoskeletal manifestations. Dermatologic manifestations include palmoplantar pustulosis, acne conglobate, acne fulminans, and hidradenitis suppurativa. Reference: Harrison&;s Principles of Internal Medicine; 19th edition; Chapter 385; Vasculitis Syndromes', 'role': 'assistant'}]