This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Adverse Drug Effect, Subject name: Pharmacology
[{'content': 'chronic use of which drug is most likely to cause osteoporosis: \nSelect and explain. \nA. Lovastatin, B. Propranolol, C. Warfarin, D. Corticosteroid', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans. D. CorticosteroidCorticosteroids antagonize the action of 1, 25 dihroxy vitamin D3 and result in loss of calcium from the kidney. Also they cause resorption of bone thus leading to osteoporosis.', 'role': 'assistant'}]