This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Other Autoimmune Disorders, Subject name: Pathology
[{'content': 'All of the following statements are true about Wiskott Aldrich syndrome except: \nSelect and explain. \nA. It is an autosomal recessive disorder, B. There is failure of aggregation of platelets in response to agonists, C. Thrombocytopenia is seen, D. Patient presents with eczema', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Wiskott-Aldrich syndrome X-linked disease characterized by thrombocytopenia, eczema, and a marked vulnerability to recurrent infection, resulting in early death. There is progressive loss of T-lymphocytes in the peripheral blood and in the T-cell zones (paracoical areas) of the lymph nodes, with variable defects in cellular immunity. Patients do not make antibodies to polysaccharide antigens, and the response to protein antigens is poor. IgM levels in the serum are low, but levels of IgG are usually normal. Paradoxically the levels of IgA and IgE are often elevated. Rx:- Allogeneic hematopoietic stem cell transplant', 'role': 'assistant'}]