This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pathology
[{'content': 'The feature that differentiate a follicular carcinoma from a follicular adenoma of thyroid is \nSelect and explain. \nA. Nuclear pleomorphism, B. Huhle cell change, C. Capsular invasion, D. Absence of colloid', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Follicular adenomas and carcinomas both are composed of well - differentiated follicular epithelial cells;the latter are distinguished by evidence of capsular and/or vascular invasion. They both have fairly uniform cells forming small follicles containing colloid. So there is no reliable cytological difference between them. (ref:ROBBINS Text book of pathology) REf img :', 'role': 'assistant'}]