This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Gynaecological oncology, Subject name: Gynaecology & Obstetrics
[{'content': 'Patient diagnosed as squamous cell intraepithelial lesion which of the following has the highest risk for progression to carcinoma; \nSelect and explain. \nA. Low grade squamous intraepithelial neoplasia, B. High grade squamous intraepithelial neoplasia, C. Squamous intraepithelial associated with HPV 16, D. Squamous intraepithelial neoplasia associated with HIV', 'role': 'user'}, {'content': 'Answer: B \nExplanation: High grade squamous intraepithelial lesion have a propensity to progress and become invasive, therefore need investigations and treatment Ref: Shaw Gynecology 17 e pg 410.', 'role': 'assistant'}]