This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Drug of choice in Acute central anticholinergic syndrome is - \nSelect and explain. \nA. Neostigmine, B. Physostigmine, C. Tacrine, D. 4-amino pyridine', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., Physostigmine Physostigmine penetrates blood-brain barrier and antagonizes both central and peripheral actions of anticholinergics in acute anticholinergic poisoning (belladonna poisoning). About other options o Neostigmine does not cross blood brain barrier. Thus it is ineffective for central anticholinergic actions. o Tacrine is used for chronic central anti-cholinergic syndrome (Alzhiemer's disease).", 'role': 'assistant'}]