This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cofactor and prosthetic groups, Subject name: Biochemistry
[{'content': 'Carboxylases require: \nSelect and explain. \nA. Vitamin B7, B. Vitamin B2, C. Vitamin B12, D. Vitamin B1', 'role': 'user'}, {'content': 'Answer: A \nExplanation: All carboxylases require Vitamin B7 i.e. Biotin. Biotin is a cofactor responsible for CO2 transfer for several carboxylase enzymes. WITH REGARD TO OTHER OPTIONS: Main biochemical role of- Vitamin B2: Oxidation-Reduction reactions, required for Glutathione Reductase Vitamin B12: Synthesis of Methionine, isomerization of Methyl Malonyl CoA to Succinyl CoA by Mutase Vitamin B1: Oxidative decarboxylation, for Transketolase of HMP.', 'role': 'assistant'}]