This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
[{'content': 'Which of the following indicate Ca breast - \nSelect and explain. \nA. Serous discharge, B. Recent retraction of nipple, C. Ulceration of nipple, D. Cracked nipple', 'role': 'user'}, {'content': "Answer: B \nExplanation: Recent retraction of the nipple may be of considerable pathological significance. A slit-like retraction of the nipple may be due to duct ectasia and chronic periductal mastitis, but circumferential retraction, with or without an underlying lump, may well indicate an underlying Ca.\nAlthough ulceration of nipple may occur in Ca breast but may occur in other conditions also.\nThe cracked nipple may occur during lactation and be the forerunner of acute infective mastitis.\nVarious degrees of cellular and architectural atypia (Atypical hyperplasia) occurs in 'Ca in situ' and 'breast Ca'.", 'role': 'assistant'}]