This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Respiratory system, Subject name: Pathology
[{'content': 'Hyperscretory granules seen in with lungCa - \nSelect and explain. \nA. Adeno Ca, B. Small cell Ca, C. Large cell Ca, D. Bronchoalveolar Ca', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ref:Textbook of pathology (Harsh mohan) 6th edition,page no.500 Small cell carcinoma: Small cell carcinomas are frequently hilar or central in location, have strong relationship to cigarette smoking and are highly malignant tumours. They are most often associated with ectopic hormone production because of the presence of neurosecretory granules in majority of tumour cells which are similar to those found in argentaffin or Kulchitsky cells normally found in bronchial epithelium. By immunohistochemistry, these tumour cells are positive for neuroendocrine markers: chromogranin, neuron-specific enolase (NSE) and synaptophysin.', 'role': 'assistant'}]