This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Karyotyping is useful in the diagnosis of? \nSelect and explain. \nA. Autosomal recessive disorders, B. Chromosomal abnormalities, C. X-linked recessive disorders, D. Biochemical abnormalities', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Karyotyping is the study of chromosomes and is used in cytogenetics to study the chromosomal abnormalities. After arresting the cells in metaphase the chromosomes are examined to see for:\n• Change in Number of chromosomes - To detect abnormalities in chromosome numbers such as aneuploidy (trisomy, tetrasomy), polyploidy.\n• For detection of structural chromosomal anomalies such as translocation, deletions, inversion of chromosomes', 'role': 'assistant'}]