This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Normal Sex Differentiation, Subject name: Gynaecology & Obstetrics
[{'content': 'First sign of puberty in females is? \nSelect and explain. \nA. Pubarche, B. Thelarche, C. Menarche, D. Increase in height', 'role': 'user'}, {'content': 'Answer: B \nExplanation: ANSWER: (B) ThelarcheREF: Nelson Textbook of Paediatrics 17th edition page 1882, http://en.wikipedia.org/wiki/PubertyRepeat in December 2009In girls, the breast bud (Thelarche) is usually the first sign of puberty (10-11 yr), followed by the appearance of pubic hair 6-12 months later. The interval to menarche is usually 2-2.5 yr but may be as long as 6 yr. Peak height velocity occurs early (at breast stage II--III, typically between 11 and 12 yr of age) in girls and always precedes menarche.STAGES OF PUBERTY:Adrenarche -Gonadarche -Thelarche -Pubarche -MenarcheSpermarcheBoth males & femalesBoth males & femalesOnly femalesBoth males 8i femalesOnly femalesOnly males7 years8 years11 years12 years12.5 years11-15 years', 'role': 'assistant'}]