This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Which of the following is an inhibitor of dihydrofolate reductase- \nSelect and explain. \nA. Phenytoin, B. Alcohol, C. Methotrexate, D. Yeast', 'role': 'user'}, {'content': "Answer: C \nExplanation: Ans. is 'c' i.e., Methotrexate o Methotrexate is folate antagonist : inhibits dihydrofolate reductase (DHP Rase) - blocking the conversion of dihydrofolic acid to tetrahydrofolic acid which is an essential co-enzyme required for one carbon transfer reactions in de novo purine synthesis and amine acid interconversions.", 'role': 'assistant'}]