This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Which of the following antibodies is most frequently seen in Antiphospholipid Syndrome? - \nSelect and explain. \nA. Anti- beta 2 glycoprotein antibody, B. Beta 2 microglobulin antibody, C. Anti-nuclear antibody, D. Anti-centromere antibody', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Antiphospholipid antibody syndrome has clinical manifestations including recurrent thrombosis, \xa0repeated miscarriages, \xa0cardiac valve vegetations and thrombocytopenia. Suspected Ab target include Beta 2 Glycoprotein 1, a plasma protein that associates with the surfaces of endothelial cells and trophoblasts.\nAnti nuclear antibody and beta 2microglobulin Ab \xa0seen in SLE.', 'role': 'assistant'}]