This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.N.S, Subject name: Pharmacology
[{'content': 'The antiepileptic drug which causes weight loss: \nSelect and explain. \nA. Valproate, B. Vigabatrin, C. Topiramate, D. Felbamate', 'role': 'user'}, {'content': 'Answer: C \nExplanation: (Ref: Katzung 14th ed. pg. 427-28)* The only antiepileptic drug which causes weight loss: Topiramate, Zonisamide* MOA of topiramate:# VG-Na+ channel blocker# Activate GABA receptor# Inhibit AMPA receptor (receptor of Glutamate)* Use:# GTCS, Partial seizure# Maintenance therapy of alcohol withdrawal# LGS# Decreases alcohol craving* Side effects: Urolithiasis, Somnolence', 'role': 'assistant'}]