This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Other topics and Adverse effects, Subject name: Pharmacology
[{'content': 'Which of the following drugs inhibits de nove synthesis of purines? \nSelect and explain. \nA. Cyclosporine, B. Tacrolimus, C. Mycophenolate, D. Infliximab', 'role': 'user'}, {'content': 'Answer: C \nExplanation: (Ref: KDT 6/e p841) By inhibiting the enzyme IMP dehydrogenase, mycophenolate inhibits the de novo synthesis of purines.', 'role': 'assistant'}]