This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pharmacology
[{'content': 'Oral contraceptive failure can occur with: \nSelect and explain. \nA. Ketoconazole, B. Aminoglutethimide, C. metyrapone, D. Glucocoicoids', 'role': 'user'}, {'content': "Answer: D \nExplanation: Rifampicin is a Microsomal enzyme inducer. It enhances the metabolism of oral contraceptives and cause failure. other enzyme inducers are phenytoin, phenobarbitone, carbamezipine, smoking, st john's wa- they can also cause contraceptive failure (REF.Essential of medical pharmacology K D TRIPATHI 6 Edition, Page No -741)", 'role': 'assistant'}]