This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Pancreas, Subject name: Pathology
[{'content': 'Most common gene associated with pancreatic cancer \nSelect and explain. \nA. KRAS, B. SMAD, C. P53, D. Rb', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. (a) KRAS(Ref Robbins 9th/pg 892-894)GeneChrPercentage KRAS12p90Most commonly involved Oncogene Qp16/CDKN2A9p95Most commonly involved Tumor suppressor gene QTP5317p50-70Involved in Response to DNA damageSMAD418q55TGF b pathwayBRCA213q10Germ-line mutation Q', 'role': 'assistant'}]