This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hypeension, Arrhythmias, Dyslipidemia, Subject name: Pharmacology
[{'content': 'All of the following antihypeensive drugs increase plasma renin activity except: \nSelect and explain. \nA. Clonidine, B. Hydralazine, C. Nifedipine, D. Captopril', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Plasma renin activity is increased by reflex increase in sympathetic discharge. Clonidine decreases central sympathetic outflow and thus will decrease the plasma renin activity. Vasodilators and ACE inhibitors result in reflex increase in plasma renin activity.', 'role': 'assistant'}]