This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Which of the following drug is used in SIADH? \nSelect and explain. \nA. Tolvapatan, B. Desmopressin, C. Vwb factor, D. Terlipressin', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. A. TolvaptanTolvaptan:Vasopressin antagonists.Orally active nonpeptide selective V2 receptor antagonist.Metabolized by CYP3A4 - Not given to patients receiving this isoenzyme inhibitor.Given once daily.t 1/2 : 6-8 hours.Actions:Increases free water clearance by kidney (aquaretic).Corrects lower plasma Na+ levels.Uses:Useful for hyponatremia treatment.Hyponatremia caused by CHF, cirrhosis of liver or syndrome of inappropriate ADH secretion (SIADH).Side effect:Thirst & dry mouth (most frequent).Fever, G.I. upset & hyperglycaemia.', 'role': 'assistant'}]