This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Medicine
[{'content': "An asymptomatic patient has proteinuria and hematuria that is glomerular in origin on a routine urinalysis. Which of the following is the most likely diagnosis? \nSelect and explain. \nA. diabetes mellitus (DM), B. amyloidosis, C. immunoglobulin A (IgA) nephropathy (Berger's disease), D. focal glomerulosclerosis", 'role': 'user'}, {'content': "Answer: C \nExplanation: Other causes of asymptomatic hematuria, with or without proteinuria, include sickle cell disease, Alport's syndrome, resolving glomerulonephritis, and thin basement disease. Berger's disease is characterized by immunoglobulin A (IgA) deposits in the mesangium. It most commonly affects older children and young adults, and is more common in Blacks than Whites. Macroscopic hematuria may occur with inter-current illness or vigorous exercise. The prognosis is variable but tends to progress slowly. Spontaneous remissions are more common in children than in adults. About 20-50% of patients develop end-stage renal disease within 20 years of diagnosis.", 'role': 'assistant'}]