This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
[{'content': 'Interleukin responsible for pyrexia is? \nSelect and explain. \nA. IL1, B. IL6, C. INF gamma, D. IFN alpha', 'role': 'user'}, {'content': 'Answer: A \nExplanation: principal mediators involved in fever IL-1 TNF prostaglandins The systemic host response to microbial infection involves clinical signs and symptoms of infection, including fever and elevated white blood cell (WBC) counts. In addition, inflammatory mediators are released, including activated complement product C3a, interleukin 6 (IL-6), and the acute-phase reactant secretory phospholipase A2 ref robbins 9th ed page 90 tab 3.7', 'role': 'assistant'}]