This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Inhalational Anesthetic Agents, Subject name: Anaesthesia
[{'content': 'MAC of the volatile agent is reduced in all of the following except \nSelect and explain. \nA. Elderly, B. Acute alcoholic intoxication, C. Pregnancy, D. Hypernatremia', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Hypernatremia causes CNS excitation thus increases MAC. Pregnancy decreases MAC because there is increase in progesterone level in pregnancy. progesterone has sedative effect on brain. age decreases MAC by 6%/decade Acute alchohol intoxication produce sedation thus decreases MAC', 'role': 'assistant'}]