This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrine System, Subject name: Physiology
[{'content': 'Which of the following increases secretion of GH? \nSelect and explain. \nA. Senescence, B. Insulin-like growth factor-1 (IGF-1), C. Somatostatin, D. Hypoglycemia', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Hypoglycemia is a potent stimulus for GH. GH decreases with aging and in response to the hypothalamic inhibitory hormone somatostatin. GH secretion would decrease in response to both exogenous GH administration and IGF-1 as a result of negative feedback inhibition', 'role': 'assistant'}]