This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'Regarding transmission of HIV to infant from infected HIV mother, which statement is/are true:a) Start zidovudine during labour.b) 25% chance of vertical transmissionc) Avoid breast feedingd) Vaccinate infant with OPV and MMRe) Cesarean section cause less transmission \nSelect and explain. \nA. abce, B. abcd, C. acde, D. abde', 'role': 'user'}, {'content': 'Answer: A \nExplanation: According to the latest edition of Williams Obs 23/e, p 1252\nAn HIV infected woman on no antiretroviral medication who presents in labour Management includes: Start zidovudine i/v\nOR\nStart zidovudine plus a single dose of nevirapine. If nevirapine is initiated, consider adding lamivudine for 7 days post partum to decrease nevirapine resistance.\nWilliams Obs 23/e, p 1251, Table 59-8, p 1252\nSo option a is correct\n\nElective cesarean is the best mode of delivery as chances of transmission of HIV are less (i.e. option e is correct)\nBreastfeeding should be avoided except in those cases where mother cannot afford formula feeds. (option c is correct).\nVertical transmission to the neonates is about 14-25%Q. (i.e. option b is correct) Transmission of HIV–2 is less frequent (1-4%) than for HIV-1 (15-40%)\n\nVaccination of HIV Infected Infant (Nelson)\n\nLive oral polio vaccine (OPV) and BCG vaccine should not be given (i.e. option d is incorrect).\nVaricella and MMR are recommended for children in immune categories. 1 and 2, but neither varicella nor MMR vaccines should be given to severely immunocompromised children (immune category 3).', 'role': 'assistant'}]