This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetics And Genetic Disorders, Subject name: Pediatrics
[{'content': 'A child presents with congenital cyanotic heart disease and polydactyly. Likely diagnosis is: \nSelect and explain. \nA. Ellis-van Creveld syndrome, B. Rubinstein-Taybi syndrome, C. McKusick - Kaufman syndrome, D. Edward syndrome', 'role': 'user'}, {'content': "Answer: A \nExplanation: a. Ellis-van Creveld syndrome(Ref: Nelson 20/e p 619', 907, 2165, 3376)Discussing about the options, one by onea. Ellis-van Creveld syndromeAlso called 'chondroectodermal dysplasia'Chondrodystrophy, polydactyly, ectodermal dysplasia, CHD (Single atrium, VSD) seenb. Rubinstein-Taybi syndromeMicrocephaly, ptosis, beaked nose with low-lying philtrum, broad thumbs and large toes, intellectual disability, VSDc. McKusick - Kaufman syndromeAlso called Cartilage-hair hypoplasia; Skeletal defects involving legs & rib cage; Immunodeficiency, celiac disease & Hirschsprung disease may be associatedd. Edward syndromeVSD, ASD, PDA, coarctation of aorta, bicuspid aortic or pulmonary valve", 'role': 'assistant'}]