This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Congenital CNS malformations, Subject name: Pediatrics
[{'content': 'In a lady with history of bih of a previous child with neural tube defect, amount of folic acid to be given in microgram as secondary prophylaxis before next conception is: \nSelect and explain. \nA. 40 microgm, B. 400 microgm, C. 4000 microgm, D. 500 microgm', 'role': 'user'}, {'content': 'Answer: C \nExplanation: To prevent NTDs, it is recommended that all women of child-bearing age, who are capable of becoming pregnant should take 0.4 mg (400 mg) of folic acid daily. If a pregnancy is planned in high risk women (with previously affected child), supplementation should be staed with 4 mg (4000 mg) of folic acid daily, beginning 1 month before the time of the planned conception.', 'role': 'assistant'}]