This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti-Neoplastic Agents, Subject name: Pharmacology
[{'content': 'True about Cyclophosphamide \nSelect and explain. \nA. Antimetabolites, B. Alkylating agent, C. Platinum compound, D. Topoisomerase inhibitors', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans. (b) Alkylating agentRef. katzung 9th ed. /1280; KDT 819-820* Cyclophosphamide is the most widely used alkylating agent.* It is an inactive compound. Transformation into active metabolite occurs in liver, and a wide range of anti tumor action is exerted.* It has prominent immunosuppressant property, so it has been particularly utilized in bone marrow transplantation. In other organ transplants it is employed only as a reserve drug.* Drugs of different category are:Alkylating agentsAntimetabolitesPlatinum compoundTopo-isomerase inhibitors* Cyclophosphamide* Ifosfamide* Mechlorethamine* Melphalan* Busulfan* Procarbazine* Nitrosourea# Carmustine# Lomustine# semustineFolic acid antagonist* MethotrexatePurine analogues* 6 Mercaptopurine* 6thioguanine* Cladribine* FludarabinePyrimidine analogues* Capecitabin* Gemcitabin* Cyatarabine and 5 FU* Cisplatin* Carboplatin* OxaliplatinTOPOISOMERASE-I* IrinotecamTOPOISOMERASE-II* Etoposide* Anthracycline# Doxorubicin# daunorubicin', 'role': 'assistant'}]