This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
[{'content': 'In donovanosis- \nSelect and explain. \nA. Pseudolymphadenopathy, B. Penicillin is used for treatment, C. Painful ulcer, D. Suppurative lymphadenopathy', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. is `a\' i.e., Pseudolymphadenopathy Donovanosis Caused by Calymmatobacterium granulomatis. C. granulomatis is ? - Gram negative - Encapsulated - Nonmotile - Intracellular It shares many morphologic and serologic characteristic (antigenic) and > 99% homology at the nucleotide level with Klebsiella. Clinical manifestations - IP --) 1-4 weeks - Begins as one or more subcutaneous nodules that erode through skin to produce clean, granulomatous, sharply defined, usually painless lesions. - The genitalia are involved in 90% of cases. - Genital swelling, paicularly of labia, is common. - In donovanosis, heaped-up granulomatous tissue may follow and subcutaneous extension to inguinal area may form "pseudo-buboes"; however, the absence of true lymphadenopathy is the hallmark of this infection. - Complications Pseudoelephantiasis, phimosis and paraphimosis. Diagnosis: - The preferred diagnostic method involves demonstration of typical intracellular Donovan bodies within large mononuclear cells visualized in smears prepared from lesions or biopsy specimens. - Stain used is wright - Giemsa Treatment: - Azithromycin (DOC) - Doxycycline (2\'d choice) - Chloramphenicol', 'role': 'assistant'}]