This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Infections of the Neonatal Infant, Subject name: Pediatrics
[{'content': 'Mastitis in infants - \nSelect and explain. \nA. Treated with antibiotics, B. More common in boys, C. It is a congential infection, D. Most common organism is E Coli', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Treated with antibiotics Infatile mastitiso Mastitis (infection of breast tissue) typically occurs in infants after 2 months of age. During the first 2 weeks of life, it occurs with equal frequency in males and females; thereafter, it is more common in girls, with a female:male ratio of approximately 2:1o This is thought to be related to the longer duration of physiologic breast hypertrophy in female infants. The majority of cases of neonatal mastitis are caused by Staphylococcus aureus; less common causes include gramnegative enteric organisms (e.g. Escherichia coli, Salmonella), anaerobes, and Group B Streptococcuso Clinically, infants usually present with unilateral swelling, erythema, warmth, tenderness, and induration of the breast, occasionally with purulent discharge from the nipple, and/or fluctuation suggesting breast abscesso Mastitis in infancy is usually a local infection, and systemic symptoms such as fever, vomiting, lethargy, and irritability are uncommon.o Much of the literature recommends treatment with parenteral antibiotics with good coverage for S. aureus.", 'role': 'assistant'}]