This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General physiology, Subject name: Physiology
[{'content': 'Which of the following is involved in transpo of large molecules from cytoplasm to the cell nucleus?(2018) \nSelect and explain. \nA. Calthrin, B. Caveolin, C. Flotillin, D. Impoins', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Clathrin mediated endocytosis is responsible for the internalization of many receptors and the ligands bound to them--including, for example, nerve growth factor(NGF). Rafts and caveolae,are involved in cholesterol regulation and transcytosis. Ref:- Ganong, pg num:-46, 47', 'role': 'assistant'}]