This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Ophthalmology
[{'content': 'Earliest manifestation of diabetic retinopathy is \nSelect and explain. \nA. Soft exudates/Cotton wool spot, B. Dot haemorrhage, C. Hard exudates, D. Microaneurysm', 'role': 'user'}, {'content': 'Answer: D \nExplanation: D i.e. Microaneurysm Microaneurysms are located in the inner nuclear layer and are the earliest and most characteristic ocular lesion Q of diabetic retinopathy.', 'role': 'assistant'}]