This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Pathology
[{'content': 'A 40 year old woman with CIN 2, next step of management \nSelect and explain. \nA. Colposcopy, B. Cyrotherapy, C. Conisation, D. Hysterectomy', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Pap Class systemReagen (WHO classification)Rucha classificationBethesda classificationClass 1Negative for malignantNegativeWithin the normal limitClass 2Inflammation/squamous atypia/koilocytes-Atypical squamous cells of unknown significance(ASCUS)Class 3Mild dysplasia(1/3rd of the sample)CIN1LSILClass 4Moderate dysplasia(1/3rd to 2/3rd of sample)Severe dysplasia(>2/3rd of sample)Carcinoma insituCIN2,3HSILClass 5Invasive cancerInvasive cancerInvasive cancerPap smear is only a screening test. Any abnormality encountered in it should be confirmed by colposcopic biopsy.Features of abnormal Pap cytologyMosaicismPunctuationsAbnormal dense nucleiGranular cytoplasmIndications for colposcopy biopsyNon-visualization of the transformation zoneObvious fungation in transformation zoneMismatch between colposcopy and pap smearStage IA-1(microinvasive)(Refer: Shaw&;s Textbook of Gynaecology, 15th edition, pg no: 402, 405)', 'role': 'assistant'}]