This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Psychiatry
[{'content': 'True about major depression is/are - \nSelect and explain. \nA. Common in males, B. Markedly diminished interest in all activities most of the day but no fatigue or loss of energy or psychomotor retardation., C. Feeling of worthlessness or excessive guilt, D. All', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Feeling of worthlessness or excessive guilt is one of the diagnostic criteria major depression.', 'role': 'assistant'}]