This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'Sustained Response to antiviral therapy (IFN + Ribavarin) in hepatitis C is indicated by \nSelect and explain. \nA. High HCV-RNA, B. Cirrhosis, C. Age > 40 years, D. Female sex', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Answer is D (Female sex): Female sex is a ourable feature, associated with sustained responsiveness to antiviral therapy Male sex is associated with reduced responsiveness. Reduced Responsiveness Genotype 1 High levels of HCV RNA Adranced fibrosis (ciorrhosis, bridging fibrosis) Long duration disease Age > 40 years I mmunosupression African American Obesity Hepatic steatosis Reduced adherence Male sex (Handbook of Gastroenterology) Sustained Responsiveness Genotype 2 and 3 Low levels of HCV RNA Minimal fibrosis Sho duration disease Age < 40 years Immunocompetance Others Absence of obesity Absence of Hepatic steatosis Increased Adherence Female sex (Handbook of Gastroenterology)', 'role': 'assistant'}]