This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
[{'content': 'Which of the following syndrome is most commonly associated with clefts of lip and palate \nSelect and explain. \nA. Apert syndrome, B. Crouzon syndrome, C. Pierre-Robin syndrome, D. Down’s syndrome', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Although most clefts of the lip and palate occur as an isolated deformity, Pierre Robin sequence remains the most common syndrome.\nThis syndrome comprises of isolated cleft palate, retrognathia and a posteriorly displaced tongue (glossoptosis), which is associated with early respiratory and feeding difficulties.', 'role': 'assistant'}]