This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Other topics and Adverse effects, Subject name: Anatomy
[{'content': 'Sirolimus is more likely than cyclosporine to cause \nSelect and explain. \nA. Hypeension, B. Osteoporosis, C. Renal insufficiency, D. Thrombocytopenia', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Clyclosporine and tacrolimus cause nephrotoxicity as an adverse effect. Sirolimus results in bone marrow suppression and thus may cause anemia ,thrombocytopenia and leukopenia', 'role': 'assistant'}]