This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Dental
[{'content': 'All statements are true regarding skin except – a) Skin is stratified squamous epithelium b) Melanocyte & merkel cells are immigrant cellsc) Keratin filaments are a hallmark of epidermal cellsd) Keratinization process cause hydration of cellse) Spines of spinous cells are formed from house keeping organelle \nSelect and explain. \nA. de, B. bc, C. cd, D. bd', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Following events occur during keratinization\n\n\nIncrease in cell size\nFlattening of cells\nAppearance of new cellular organelles, e.g. lamellar granules in stratum spinosum, keratohyaline granules and oadland bodies in stratum granulosum.\nMetabolism changes from generalized to more focused with the synthesis of molecules (structural proteins and lipids) related to keratinization.\nProgressive dehydration (not hydration).\nProgressive shortening and final disappearance of the nucleus.\nChanges in enzymes with degradation of cellular organelles and chromatin fragmentation →\xa0apoptosis in stratum corneum.\nFinally, dead cells to break apart and slough away, a process is known as desquamation.', 'role': 'assistant'}]