This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chronic and Cystic Diseases, Subject name: Pathology
[{'content': 'Adult PCKD is? \nSelect and explain. \nA. Autosomal dominant, B. Autosomal recessive, C. X-linked recessive, D. Mitochondrial inheritance', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans is 'a' i.e. Autosomal dominant o ADPKD is an autosomal dominant disorder characterized by multiple expanding cysts of both kidneys that ultimately destroy renal parenchyma and cause renal failure in middle life (40-60 years of age)o Most commonly (85%) mutation involves PKD 1 gene on chromosome 16 encoding for polycystin 1 followed by PKD2 gene on chromosome 4 encoding for polycystin 2.", 'role': 'assistant'}]