This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
[{'content': 'Heme is conveed to bilirubin mainly in: \nSelect and explain. \nA. Kidney., B. Liver., C. Spleen, D. Bone marrow.', 'role': 'user'}, {'content': 'Answer: C \nExplanation: C i.e. Spleen Breakdown of heme to bilirubin occurs in macrophages of the reticuloendothelial system mainly in the spleenQ also in the liver and bone marrow.', 'role': 'assistant'}]