This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hypeension, Arrhythmias, Dyslipidemia, Subject name: Pharmacology
[{'content': 'Which of following HMG CoA reductase inhibitor has longest half life? \nSelect and explain. \nA. Atorvastatin, B. Simvastatin, C. Rosuvastatin, D. Pitavastatin', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Rosuvastatin - Longest acting Pitavastatin - most potent - Statins have maximum LDL lowering capacity. - Given at night because HMG CoA reductase is maximum active at night but Atorvastatin and Rosuvastatin are long acting drugs, thus can be given any time of the day. - Statins can cause myopathy', 'role': 'assistant'}]