This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Antimicrobial Drugs, Subject name: Pharmacology
[{'content': 'Which of the following statement about Bedaquiline is TRUE: \nSelect and explain. \nA. Mycobacterial ATP synthase inhibitor, B. Does not prolongs QT interval, C. It should be given alone, D. It has cross-resistance with rifampicin', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Bedaquiline: - New antitubercular drug for MDR or XDR,- It act by inhibiting ATP synthase in mycobacteria- Food increases the bioavailability - Given along with base line antitubercular drug- Recent studies have shown cross resistance with clofazimine only. It is approved for use for 6 month. Side effect: - Derangement of LFT- Prolongs QT interval Pretomanid in combination withBedaquiline and Linezolid is approved by the FDA for the treatment of extensively drug-resistant, treatment-intolerant or nonresponsive multidrug-resistant pulmonary TB', 'role': 'assistant'}]