This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Clinical Aspects of Neoplasia, Subject name: Pathology
[{'content': 'Retinoblastoma is associated with - \nSelect and explain. \nA. Osteosarcoma, B. Hepatocellularca, C. SCC, D. Osteoclastoma,', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Osteosarcoma o Patients with familial retinoblastoma are at increased risk of developing osteosarcoma and some other soft tissue sarcomas.o Also, inactivation of the RB locus has been noted in several other tumors, including adenocarcinoma of the breast, small cell carcinoma of the lung, and bladder carcinoma.", 'role': 'assistant'}]