This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Medicine
[{'content': 'Anemia of chronic disease is characterized by all, except - \nSelect and explain. \nA. Decreased serum iron, B. Increased total iron binding capacity (TIBC), C. Increased serum ferritin, D. Increased macrophage iron in bone marrow', 'role': 'user'}, {'content': 'Answer: B \nExplanation: <p>In anemia of chronic disorder , there is defective red cell production & reduced red cell life span.</p><p>Laboratory findings include reduced serum iron, low to normal TIBC,raised serum ferritin,& bone marrow examination reveals normal erythroid maturation with red cell precursor having reduced stainable iron than normal , while macrophages in the marrow containing increased amount of iron.</p><p>Reference : Harsh mohan textbook of pathology 6th edition pg no 302 </p>', 'role': 'assistant'}]