This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
[{'content': 'Which of the following statement regarding Wiskott aldrich syndrome is TRUE? \nSelect and explain. \nA. Primary defect is B cell defect, B. Primary defect is T cell defect, C. Associated with WASP gene mutation, D. Defect in phagocytosis', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Wiskott Aldrich syndrome is caused by mutation in the WASP gene which produces a protein Wiskott Aldrich syndrome protein. WASP gene is located on the sho arm of X chromosome. It is an X linked immunodeficiency disorder Cardinal features are: Thrombocytopenia Recurrent pyogenic and oppounistic infections staing from 6 months of age Eczema of varying degrees staing at about 1 year of age Normal serum levels of IgA and IgE, slightly increased IgG and decreased amount of IgM. Defective T cell function Normal B cell function', 'role': 'assistant'}]