This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pediatrics
[{'content': 'In Pheochromocytoma, which of the following is increased in urine? \nSelect and explain. \nA. VMA, B. Aldosterone, C. Cortisol, D. 17 hydroxyprogesterone', 'role': 'user'}, {'content': "Answer: A \nExplanation: a. VMA(Ref: Nelson's 20/e p 2227-2729, Ghai 8/e p 525)Biochemical tests for Pheochromocytoma:Pheochromocytomas synthesize and store catecholamine, so elevated plasma and urinary levels of catecholamines methylated metabolites (VMA or vanillyl mandelic acid), metanephrines, are the cornerstone for the diagnosisAmong these tests, the fractionated metanephrines and catecholamines are the most sensitive.QIn contrast to adults with pheochromocytoma in whom both norepinephrine and epinephrine are elevated, children with pheochromocytoma predominantly excrete norepinephrine in the urine.", 'role': 'assistant'}]