This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Vascular surgery, Subject name: Surgery
[{'content': "Malignant cell in Hodgkin's lymphoma is \nSelect and explain. \nA. Reed stenberg cell, B. Lymphocytes, C. Histocytes, D. Reticulum cells", 'role': 'user'}, {'content': 'Answer: A \nExplanation: Reed-Sternberg cells (also known as lacunar histiocytes for ceain types) are distinctive, giant cells found with light microscopy in biopsies from individuals with Hodgkin\'s lymphoma (a.k.a. Hodgkin\'s disease, a type of lymphoma). They are usually derived from ,B lymphocytes classically considered crippled germinal center B cells, meaning they have not undergone hypermutation to express their antibody. Seen against a sea of B cells, they give the tissue a moth-eaten appearance. Reed-Sternberg cells are large (30-50 microns) and are either multinucleated or have a bilobed nucleus with prominent eosinophilic inclusion-like nucleoli (thus resembling an "owl\'s eye" appearance)', 'role': 'assistant'}]