This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'All of the following statements are true regarding lipoproteins except \nSelect and explain. \nA. VLDL transports endogenous lipids, B. LDL transports lipids to the tissues, C. Increased blood cholesterol is associated with increased LDL receptors, D. Increased HDL is associated with decreased risk of coronary disease', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Increased blood cholesterol is associated with increased LDL receptors\xa0\n\nIncreased blood cholesterol (hypercholesterolemia) causes downregulation of LDL receptors.\nVLDL transports endogenous lipids (especially TGs)\nLDL transports lipids (especially cholesterol) to extrahepatic tissues.\nIncrease HDL is protective against cardiovascular diseases.', 'role': 'assistant'}]