This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': "A married middle aged female gives history of repeated abortions for the past 5 years. Which of the following chromosomal anomaly is the most common cause for this? \nSelect and explain. \nA. Klinefelter's syndrome, B. Turner's syndrome, C. Down's syndrome, D. Patau's syndrome", 'role': 'user'}, {'content': 'Answer: C \nExplanation: • The given karyogram shows three chromosomes at 21 instead of a pair. It is called Trisomy 21.\n• Trisomy 21 is synonymous with Down’s syndrome and is the most common of the chromosomal disorders. It is a major cause of mental retardation.\n• Other trisomies are Edward syndrome (Trisomy 18) and Patau syndrome (Trisomy 13)', 'role': 'assistant'}]