This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'An example of CXC chemokine is_____. \nSelect and explain. \nA. IL 8, B. IL 2, C. Lymphotactin, D. Fractalkine', 'role': 'user'}, {'content': 'Answer: A \nExplanation: C-X-C chemokines have one amino acid residue separating the first two of the four conserved cysteines. These chemokines\xa0act primarily\xa0 on neutrophils.\xa0IL-8\xa0 (now called CXCL8) is typical of this group. It is secreted by activated macrophages, endothelial cells, and other cell types, and causes activation and chemotaxis of neutrophils,\xa0with\xa0limited\xa0activity\xa0on\xa0monocytes\xa0and\xa0eosinophils. Its most important inducers are microbial products and cytokines, mainly IL-1 and TNF.\nReference-Robbins BASIC PATHOLOGY 10th edition pg-74', 'role': 'assistant'}]