This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Which of the following about Nonbacterial thrombotic endocarditis (NBTE) is false? \nSelect and explain. \nA. Characterized by\xa0the\xa0deposition\xa0of\xa0sterile thrombi\xa0on\xa0cardiac valves, B. The vegetations in NBTE are typically small (1 to 5 mm in diameter), C. Valvular\xa0damage\xa0is\xa0a\xa0prerequisite for NBTE to occur, D. Hypercoagulable\xa0states are\xa0the\xa0usual\xa0precursor to NBTE', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Nonbacterial thrombotic endocarditis (NBTE) is characterized by the deposition of sterile thrombi on cardiac valves,\xa0typically in those with an underlying hypercoagulable state.\xa0 Although\xa0NBTE\xa0can occur in otherwise healthy individuals, a wide variety of diseases associated with general debility or wasting are associated with an increased risk for NBTE—hence the alternate term marantic endocarditis. In contrast to infective endocarditis, the sterile valvular lesions of NBTE are nondestructive.\nThe vegetations in NBTE are typically small (1 to 5 mm in diameter)\xa0 and valvular damage is not a\xa0prerequisite.\xa0Indeed, the condition usually occurs on previously normal valves.\xa0Rather, hypercoagulable states are the usual precursor to NBTE; such conditions include chronic disseminated intravascular coagulation,\xa0hyperestrogenic states, and those associated with underlying malignancy, particularly mucinous adenocarcinomas.\xa0This last association probably relates to the procoagulant effect of circulating mucin and/or tissue factor elaborated by these tumors. Endocardial trauma, such as from an indwelling catheter, also is a well-recognized predisposing condition.\nRobbins BASIC\xa0 PATHOLOGY T E N T H\xa0 \xa0E D I T I O N, Page No:428', 'role': 'assistant'}]