This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hematology, Subject name: Pharmacology
[{'content': 'Antidote of heparin is \nSelect and explain. \nA. CaNaEDTA, B. Protamine sulfate, C. Deferiprone, D. d - penicillamine', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., Protamine sulfate Protamine sulfate* It is a strongly basic, low molecular weight protein obtained from the sperm of certain fish.* Given i. v. it neutralizes heparin weight for weight, i.e., 1 mg is needed for every 100 U of heparin.* It is needed only when the heparin action needs to be terminated rapidly, e.g., after cardiac or vascular surgery.* In absence of heparin, protamine itself acts as a weak anticoagulant by interacting with platelets and fibrinogen.", 'role': 'assistant'}]