This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pharmacology, Subject name: Pharmacology
[{'content': 'Tolerance and physical dependence may occur after chronic use of all of the following agents Except \nSelect and explain. \nA. Meperidine, B. Phenobarbital, C. Diazepam, D. Clomipramine', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Tolerance and physical dependence can occur after chronic administration of most central nervous system depressants, including ethanol, barbiturates, benzodiazepines (diazepam), and opiates (meperidine). Tolerance and physical dependence are not associated with most antiepileptics, antidepressants, neuroleptics, and lithium. Ref: KD Tripathi 8th ed.', 'role': 'assistant'}]