This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Thalassemia major manifests in- \nSelect and explain. \nA. Childhood, B. Puberty, C. Adolescence, D. Middle age', 'role': 'user'}, {'content': 'Answer: A \nExplanation: None', 'role': 'assistant'}]