This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Inborn Errors of Metabolism, Subject name: Pediatrics
[{'content': 'Wrinkled paper appearance of macrophage in bone marrow aspirate is seen in: \nSelect and explain. \nA. Niemann Pick disease, B. Gaucher disease, C. Hemophagocytic lymphohistiocytosis, D. Langerhan cell histiocytosis', 'role': 'user'}, {'content': 'Answer: B \nExplanation: b. Gaucher disease(Ref: Nelson\'s 20/e p 708-712, Ghai 8/e p 659-664)Gaucher cells are Lipid Laden Macrophages have a characteristic histologic appearance of "wrinkled tissue paper"Membrane-bound inclusions filled with glucocerebroside are seen with electron microscopy.', 'role': 'assistant'}]