This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cytogenetic Disorders, Subject name: Pathology
[{'content': "Karyotype in Klinefelter's syndrome is? \nSelect and explain. \nA. 47 XXY, B. 45XO, C. 46XXY, D. 45XXX", 'role': 'user'}, {'content': "Answer: A \nExplanation: ANSWER: (A) 47XXYREF: Harrison's 18th ed table 349-2 Genitalia DisorderCommon Chromosomal ComplementGonadExternalInternalBreastDevelopmentKlinefelter'ssyndrome47,XXY or 46.XY/47.XXYHyalinized testesMaleMaleGynecomastia Clinical Features Small testes, azoospermia, decreased facial and axillary hair, decreased libido, tall stature and increased leg length, decreased penile length, increased risk of breast tumors, thromboembolic disease, learning difficulties, obesity, diabetes mellitus, varicose veins", 'role': 'assistant'}]