This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General anatomy, Subject name: Anatomy
[{'content': 'In a patient with nephrotic syndrome and hypoalbuminemia,protein binding of which drug will not be affected \nSelect and explain. \nA. Tolbutamide, B. Morphoine, C. Diazepam, D. Valproate', 'role': 'user'}, {'content': 'Answer: A \nExplanation: all drugs listed in the optiond are highly plasma protein bound(>90%)whereas morphine has only 35% binding to plasma proteins. Moreover ,morphine is a basic drug and binds to alpha1 -acid glycoprotein(not album)', 'role': 'assistant'}]