This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Medicine
[{'content': 'True regarding multiple myeloma are all except \nSelect and explain. \nA. Plasmacytosis less than 10%, B. increased IgG, C. ANA antibody, D. Incrased M spikes', 'role': 'user'}, {'content': 'Answer: A \nExplanation: In multiple myeloma , marrow plasmacytosis will be more than 10%.On serum electrophoresis ,the paraprotein usually appears as a single narrow homogenous M-band component. Most frequent paraprotein is IgG seen in about 50% cases of myeloma. Reactive plasmacytosis can occur in disorders such as aplastic anemia, rheumatoid ahritis ,SLE,cirrhosis of liver,metastatic cancer & chronic inflammation & infection such as tuberculosis .So ANA antibody may become positive .Reference :Harsh mohan textbook of pathology 6th edition pg no 382.', 'role': 'assistant'}]