This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Methylation of cytosine resiclues results in ? \nSelect and explain. \nA. Point mutation, B. Decreased expression of gene, C. Increased expression of gene, D. Aneuploidy', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Methylation makes the DNA mute.', 'role': 'assistant'}]