This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'TRUE statements concerning malaria includea) Malaria caused by each of the  four plasmodial species can relapse after initial illnessb) Red cells negative for the Duffy blood group antigen are resistant to Plasmodium vivaxc) Renal impairment is a grave prognostic sign in falciparum malariad) Plasmodium malariae can cause immune-mediated nephropathy \nSelect and explain. \nA. ac, B. bd, C. c, D. d', 'role': 'user'}, {'content': 'Answer: B \nExplanation: P. vivax needs Duffy Antigen to enter the red cells, patients who lack this antigen are resistant to P.vivax infection.\nRenal failure can occur d/t P. malaria infection. It is d/t deposition of soluble immune complexes in the glomeruli.\n\nThe manifestation of falciparum malaria is\n\nComa\nAcidosis\nSevere normocytic normochromic anaemia\nRenal failure\nNon-cardiogenic pulmonary edema\nHypoglycemia\nHypotension/shock\nDIC\nConvulsion\nHemoglobinuria\nJaundice\n\nOut of these major features, only 2 features carry grave prognosis :\n\nComa\nHypoglycemia\nRenal failure in falciparum malaria seems to occur on the basis of tubular sequestration of parasitized erythrocytes and tends to resolve spontaneously.\nMalaria caused by only 2 species of Plasmodium can relapse\nPlasmodium vivax & Plasmodium Ovale', 'role': 'assistant'}]