This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'A chronic alcoholic has an elevated serum alpha fetoprotein levels. Which of the following neoplasms is most likely - \nSelect and explain. \nA. Prostatic adenocarcinoma, B. Multiple myeloma, C. Hepatocellular carcinoma, D. Glioblastoma multiforme', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Elevated levels of serum α-fetoprotein are found in 50 to 75% of patients with HCC.\nFalse-positive results are encountered with yolk-sac tumors and many non-neoplastic conditions, including cirrhosis, massive liver necrosis, chronic hepatitis, normal pregnancy, fetal distress or death, and fetal neural tube defects such as anencephaly and spina bifida.\nConcept\nThe staining for Glypican-3 is used to distinguish early hepatocellular carcinoma from a dysplastic nodule. Other tests cannot be used because the levels of serum α-fetoprotein are inconclusive in this condition.', 'role': 'assistant'}]