This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
[{'content': 'During acclimatization to high altitude all of the following take place except \nSelect and explain. \nA. Increase in minute ventilation, B. Increase in the sensitivity of central chemoreceptors, C. Increase in the sensitivity of carotid body to hypoxia, D. Shift in the oxygen dissociation curve to the left', 'role': 'user'}, {'content': 'Answer: D \nExplanation: At high altitude there can be acute changes and changes due to acclimatization.\nAcute mountain sickness\n\nDyspnoea, dizziness, tiredness, tachycardia, palpitation, nausea, vomiting etc.\nAt higher altitudes- pulmonary edema and cerebral edema may occur.\n\nAcclimatization changes\n\nHyperventilation leading to respiratory alkalosis\nIncreased 2,3DPG- Hb-O2 dissociation curve shifts to right.\nIncreased erythropoietin leading to absolute polycythemia\nIncreased renal excretion of bicarbonate\nIncreased tissue vascularity\nIncreased oxidative metabolism\nIncreased diffusion capacity of lung\nIncreased myoglobin', 'role': 'assistant'}]