This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Development and Epidemiology, Subject name: Pediatrics
[{'content': "First Sign of Pubertal devlopment in female is - \nSelect and explain. \nA. Enlargement of breast, B. Menarche, C. Appearance of pubic hair, D. Appearance of axillary' hair", 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. is Enlargement of breast o In male - Sequence of change 1. Growth of testes (> 3 ml in volume or & thinning of scrotum 2-5 cm in longest diameter) 2. Pigmentation of scrotum & growth of penis 3. Pubic hair 4. Axillary hair o In female - 1. Breast bud - First sign 2. Pubic hair 3. Menarche', 'role': 'assistant'}]