This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chronic Kidney Disease & Diabetic Nephropathy, Subject name: Medicine
[{'content': 'Which of the following drug does not cause nephrotoxicity? \nSelect and explain. \nA. Cisplatin, B. Cyclophosphamide, C. Cyclosporine, D. Sirolimus', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Sirolimus is a non-nephrotoxic -mTOR inhibitor with a long half-life of 62 hours. It was the first mTOR inhibitor to be developed in solid organ transplantation as it inhibits cell proliferation .', 'role': 'assistant'}]