This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Bater syndrome, Gitelman syndrome, Liddle and Comparison with SIADH, Subject name: Medicine
[{'content': 'Causes of severe hypokalemic metabolic alkalosis with severe hypeension include \nSelect and explain. \nA. Liddle syndrome, B. Bater syndrome, C. Gitelman syndrome, D. Renal tubular acidosis', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Liddle syndrome - AD, gain-in-function mutations of ENaC subunits. Activating kidneys to excrete potassium retaining excessive sodium & water, leading to hypeension. C/F- severe hypeension with hypokalemia, unresponsive to spironolactone yet sensitive to amiloride', 'role': 'assistant'}]