This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
[{'content': 'All of the following factors increased acid secretion in the stomach, EXCEPT: \nSelect and explain. \nA. Histamine, B. Acetylcholine, C. Food in stomach, D. Gastrin', 'role': 'user'}, {'content': "Answer: C \nExplanation: Factors which increase the acid secretion in stomach are vagal stimulation(acetyl choline), gastrin and histamine. Gastrin and acetylcholine promote secretion by elevating cytosolic free calcium concentrations, whereas histamine increases intracellular cAMP. Factors that inhibit HCl secretion are: Low pH in the stomach by negative feedback mechanism Intestinal influences Somatostatin Prostaglandins, epidermal growth factor transforming growth factor Ref: Barrett K.E., Barman S.M., Boitano S., Brooks H.L. (2012). Chapter 25. Overview of Gastrointestinal Function & Regulation. In K.E. Barrett, S.M. Barman, S. Boitano, H.L. Brooks (Eds), Ganong's Review of Medical Physiology, 24e.", 'role': 'assistant'}]