This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Medical, surgical and gynaecological illness complicating pregnancy, Subject name: Gynaecology & Obstetrics
[{'content': 'Regarding transmission of HIV to infant from infected HIV mother, which statement is/are true: \nSelect and explain. \nA. Sta zidovudine during labour, B. 25% chance of veical transmission, C. Avoid breastfeeding, D. Vaccinate infant with OPV and MMR', 'role': 'user'}, {'content': "Answer: A \nExplanation: Zidovudine is given IV Infusion staing at onset of labour or4 hours prior to CSsection,Loading dose is 2mg/kg/hr and maintainance dose is 1mg/kg/hr Transplacental transmission occurs :20% before 36 weeks,50% before delivery,30% during labour Breast feeding doubles risk of MTCT but alternative forms of infant nutrition are not safe. D.C.DUTTA'S TEXTBOOK OF OBSTETRICS,Pg no:283,9th edition", 'role': 'assistant'}]