This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Apoptosis, Subject name: Pathology
[{'content': 'Arrange the steps in apoptosis in sequence of occurrence: 1. Release of cyt c in cytoplasm2. Activation of APAF-13. Removal of BCL-2 4. Caspase activation \nSelect and explain. \nA. 3-1-2-4, B. 4-2-1-3, C. 1-2-4-3, D. 3-2-4-1', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Intrinsic Pathway of Apoptosis:- Apoptosis causes fragmentation of DNA, which gives Step-Ladder pattern on DNA gel electrophoresis.', 'role': 'assistant'}]