This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'An example of a tumor suppressor gene is- \nSelect and explain. \nA. myc, B. fos, C. ras, D. RB', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Tumor suppressor gene\nThe replication of cell should be controlled to maintain a steady state.\nFailure to inhibit cell replication is one of the fundamental alterations in the process of carcinogenesis.\nTumor suppressor genes are the genes whose products downregulate the cell cycle and thus apply brakes to cellular proliferation.\nSo, loss of function of tumor suppressor genes results in uncontrolled cell proliferation and carcinogenesis.\n\xa0Similar to an oncogene, tumor suppressor gene may be -\nCell surface receptor\n\xa0Transduction molecules\nTranscription factor.\nIn addition,\nCell cycle inhibitors\nRegulators of cellular responses to DNA damage (DNA repair regulators) \nThese protein products are involved in -\nCell cycle control\nRegulation of apoptosis \nDNA', 'role': 'assistant'}]