This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Which of the following surface glycoproteins is most often expressed in human hematopoietic stem cell \nSelect and explain. \nA. CD 22, B. CD 40, C. CD 15, D. CD 34', 'role': 'user'}, {'content': "Answer: D \nExplanation: Ans. is 'd' i.e., CD 34 o Lymphocytes and other leukocytes have a number of surface antigens or marker --> leukocyte differentiation antigen. o A paicular leucocyte differentiation antigen has been given a CD (cluster of differentiation) number on the bases of its reaction with a cluster of monoclonal antibodies. o These markers reflect the stage of differentiation and functional propeies of cell. Primary T cell Associated -> CD 1, CD3, CD4, CD5, CD8 Primary B cell associated --> CD 10, CD 19, CD20, CD21, CD23, CD79a Primary monocyte or macrophage associated --> CD1 1 c, CD 13, CD 14, CD 15, CD33, CD64 Primary NK cell associated --> CD16, CD56 Primary stem cell and progenitor cell associated 3 CD34 Activation markers -3 CD30 Present on all leukocytes -3 CD45", 'role': 'assistant'}]