This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Retina, Subject name: Ophthalmology
[{'content': 'Which of the following agents is not used in the treatment of Diabetic Macular Edema/Retinopathy: \nSelect and explain. \nA. Ruboxistaurim, B. Pyridazinones, C. Benfotiamine, D. Tamoxifen', 'role': 'user'}, {'content': "Answer: D \nExplanation: Ans. (d) TamoxifenRef: Yanoff 3/e, p. 645Tamoxifen is known to cause retinopathy and macular edema as an adverse effect. It is not used in the treatment of Diabetic Macular edema or retinopathy.* Ruboxistaurin - PKC inhibitor* Pyridazinones/Spiroimides/corbotyliz acid -- aldose reductase inhibitors* Benfoliamine -|levels of AGE's", 'role': 'assistant'}]