This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Lipids, Subject name: Biochemistry
[{'content': 'In well fed state, the activity of Carnitine Palmitoyl Transferase-1 in outer mitochondrial membrane is inhibited by: \nSelect and explain. \nA. Glucose, B. Acetyl-CoA, C. Malonyl-CoA, D. Pyruvate', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans. C. Malonyl-CoA(Ref Harper 31/e page 214)Fatty acid oxidation is inhibited in the well fed state because, CPT-I activity is low in fed state because of inhibition by malonyl-CoA, the initial intermediate in fatty acid synthesis formed by acetyl-CoA carboxylase.', 'role': 'assistant'}]