This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Anaesthesia
[{'content': 'Local anaesthetics acts by inhibiting: March 2012 \nSelect and explain. \nA. Sodium channels, B. Potassium channels, C. Calcium channels, D. Magnesium channels', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans: A i.e. Sodium channels Local anaesthetics act by inhibiting sodium channels from inside Local anesthetics Generally blocks: Sodium channels Potency of LA depends on: Lipid solubility Susceptibility of fibres to LA: Type B > type C > type A Amide linked LA: - Lidocaine, - Bupivacaine etc. Ester linked LA: - Cocaine,', 'role': 'assistant'}]