This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'Following antibiotics are safe to treat UTI in pregnancy:a) Aminoglycosidesb) Penicillinc) Cotrmoxazoled) Ciprofloxacine) Cephalosporins \nSelect and explain. \nA. ab, B. ad, C. be, D. ce', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Principles for management of UTI during pregnancy:\n\nSingle dose therapy is preferred\nThe antimicrobial agent should be appropriate to the mother and fetus, any one of the following drugs could be prescribed:\n\n– Ampicillin\n– Nitrofurantoin – DOC for prophylaxis of recurrent UTI in pregnancy\n– Cephalexin Cephalosporin\n– Amoxicillin clavulanic acid combination.\n\nSulfonamides should not be given in the third trimester because they may interfere with bilirubin binding and thus impose a risk of neonatal hyperbilirubinemia and kernicterus.\nFluoroquinolones are also contraindicated because of their potential teratogenic effects on fetal cartilage and bone.\nTetracyclines, cotrimoxazole and ciprofloxacin are: contraindicated during pregnancy.', 'role': 'assistant'}]