This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Fluid & Electrolyte, Subject name: Surgery
[{'content': "In fluid replacement following a 20% BSA burn, the fluid requirement for the initial 24-hour period is dependent on which of the following? \nSelect and explain. \nA. Patient's weight, B. Serum Na, C. CO level, D. Acid base status", 'role': 'user'}, {'content': 'Answer: A \nExplanation: In burns, the Parkland formula is used to calculate initial fluid management. Fluid requirement =4xweight(kg)x% second and third degree BSA. Half this volume is given over the first 8 hours from time of the burn and the other half over the next 16 hours. After the initial 24-hour period, clinical parameters are used to guide fluid management.', 'role': 'assistant'}]