This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'The most clinically significant skin eruption associated with M. pneumoniae infection is: \nSelect and explain. \nA. Erythema multiforme major, B. Bullous eruptions, C. Toxic epidermal necrosis, D. Pyostomatitis vegetans', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Erythema multiforme major (Stevens-Johnson syndrome) is the most clinically significant skin eruption associated with M. pneumoniae infection. Ref:Harrisons Principles of Internal Medicine, 18th Edition, Page 1418', 'role': 'assistant'}]