This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Acute coronary syndrome, Subject name: Medicine
[{'content': 'Tadalafil is contraindicated in? \nSelect and explain. \nA. Pulmonary aery hypeension, B. Chronic stable angina (acute episode), C. Active infections, D. Hepatic dysfunction', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Tadalafil is C/I with NTG which is taken for acute attack of angina as in this case. Tadalafil- Uses: For erectile dysfunction For symptoms of BPH Nitrates should not be used within 24 hours of sildenafil, tadalafil, or vardenafil (may produce severe hypotension) Nitrates- C/I in the presence of hyperophic CMP or severe Aoic Stenosis MC side effect of nitrate treatment is headache Hypotension may occur in hypovolemic patients. Development of tolerance To avoid nitrate tolerance, a daily 8 to 12 hour interval free of nitrate exposure is recommended', 'role': 'assistant'}]