This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Bioavailability ? \nSelect and explain. \nA. Area of oral/ area of IV, B. Area of IV/ area of oral, C. Area of oral/ area of IV x 100, D. Area of IV/ area of oral x 100', 'role': 'user'}, {'content': "Answer: C \nExplanation: Ans. is 'c' i.e., Area of oral/ area of IV x 100 Bioavailability Refers to the rate and extent of absorption of drug from a dosage form as determined by its concentration-time curvein blood or by its excretion in urine. It is the measure of fraction (F) of drug, which reaches the systemic circulation in unchanged form. Bioavailability of a drug given by i.v.route is 100%. So the bioavailability of drug dosage form is determined by comparing it with the i.v.route.", 'role': 'assistant'}]