This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy, Subject name: Pharmacology
[{'content': 'Which anticancer drug causes hypercoagulable syndrome? \nSelect and explain. \nA. 5-FU, B. L-asparaginase, C. Melphalan, D. Carmustine', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Hypersensitivity reaction manifested by fever, chills, nausea, and vomiting, uicaria, bronchospasm, respiratory failure and hypotension; i ed risk of both clotting and bleeding as a result of alterations in various clotting factors; pancreatitis, and neurological toxicity. Ref: KD Tripathi 8th ed.', 'role': 'assistant'}]