This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Anatomy
[{'content': 'WAGR syndrome is caused by defect in which chromosome: \nSelect and explain. \nA. 6, B. 10, C. 11, D. 14', 'role': 'user'}, {'content': "Answer: C \nExplanation: WAGR syndrome is characterized by genital anomalies, aniridia, hemihyperophy, and Wilms' tumor. The constellation of defects is due to a microdeletion in chromosome 11 that includes both the PAX6 (aniridia) and WT1 genes that are only 700 kb apa. Ref: Langman's embryology 11th edition Chapter 15.", 'role': 'assistant'}]