This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Thyroid Tumor, Subject name: Pathology
[{'content': 'The expression of the following oncogene is associated with a high incidence of medullary carcinoma of thyroid: \nSelect and explain. \nA. p 53, B. Her 2 neu, C. RET proto oncogene, D. Rb gene', 'role': 'user'}, {'content': 'Answer: C \nExplanation: - RET proto-oncogene is mutation is associated with medullary carcinoma of thyroid - RET proto-oncogene is mutated in MEN-2A & 2B syndromes, hence these are also associated with medullary carcinoma of thyroid. - Prophylactic thyroidectomy is indicated in pt with family history of RET mutation', 'role': 'assistant'}]