This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Neuromuscular Blocker, Subject name: Anaesthesia
[{'content': 'Factors responsible for cardiovascular effects of non depolarizing neuromuscular blockers:- \nSelect and explain. \nA. Histamine release, B. Effects mediated by autonomic nicotinic cholinergic receptors, C. Pancuronium produced a profound vagolytic response, D. All of the above', 'role': 'user'}, {'content': 'Answer: D \nExplanation: All benzylisoquinoline except cisatracurium causes histamine release - | BP | HR - CVS Effects mediated by autonomic nicotinic Cholinergic receptor ex. Pancuronium (vagal blockade) | BP | HR Pancuronium produced a profound vagolytic response characterized by tachycardia, reduction in hea rate variability and baroreflex sensitivity .', 'role': 'assistant'}]