This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': "Cause of liver cirrhosis in childhood include – \nSelect and explain. \nA. Alpha–1 antitrypsin deficiency, B. Coeliac disease, C. Phenylketonuria, D. Cow's milk intolerance", 'role': 'user'}, {'content': 'Answer: A \nExplanation: Cirrhosis in children \n\nCirrhosis is a histologically defined condition of the liver characterized by diffuse hepatocyte injury and regeneration.\nCauses of cirrhosis in children are -\n\n1) Post necrotic\n\nViral hepatitis -p HBV, HCV\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0 ❑ Idiopathic neonatal hepatitis\xa0\xa0 o-antitrypsin deficiency\nAutoimmune or drug induced hepatitis\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0 ❑ Wilson disease\xa0\xa0 ❑ Hethochromatosis\nTyrosinemia\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0 ❑ Galactosemia\n\n2) Biliary\n\nBiliary atresia\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0 ❑ Choledochal cyst\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0 ❑ Tumor of bile duct\nCaroli disease\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0\xa0 ❑ Cystic fibrosis ❑ Primary sclerosing cholangitis\nPFIC\xa0\xa0\xa0\xa0\xa0\xa0 ❑ Paucity of intrahepatic bile ducts\n\n3. Hypersensitivity to drug -3 Phenytoin\n4. Parasites -3 Opisthorchis sinensis, Ascaris, Fasciola.', 'role': 'assistant'}]