This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Irreversible cell Injury/Necrosis, Subject name: Pathology
[{'content': 'CAR-T cells are used in the treatment of which of the following cancers? \nSelect and explain. \nA. Acute lymphoblastic leukemia, B. Soft tissue sarcoma, C. Medulloblastoma, D. Small cell lung carcinoma', 'role': 'user'}, {'content': 'Answer: A \nExplanation: CAR-T cells Chimeric antigen receptor (CAR) T cells are T-cells extracted from patient and modified in vitro to change T-cell receptor to detect specific protein on surface of malignant cells such as CD19 Currently approved for use in acute lymphoblastic leukemia and B-cell NHLs Examples of CAR-T cells are Kymria (ALL), Yescaa (DLBCL)', 'role': 'assistant'}]