This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Disorders of Carbohydrate Metabolism, Subject name: Pediatrics
[{'content': "A child presents with hepatomegaly and hypoglycemia. There is no improvement in blood sugar even after administration of epinephrine. What is the likely diagnosis? \nSelect and explain. \nA. Von Gierke's disease, B. Anderson's disease, C. Pompe's disease, D. Mc Ardle's disease", 'role': 'user'}, {'content': 'Answer: A \nExplanation: Epinephrine- | blood glucose level by stimulating glycogenolysis and gluconeogenesis, mediated by glucose 6 phosphatase- conves Glucose-6-phosphate to Glucose Von Gierke disease- deficiency of Glucose 6 phosphatase enzyme Hence, epinephrine is not able to increase blood glucose in a child with Von Gierke disease, but lactate levels increase.', 'role': 'assistant'}]