This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of carbohydrate, Subject name: Biochemistry
[{'content': 'Transamination of aspaate leads directly to -------- of the citric acid cycle \nSelect and explain. \nA. Citrate, B. Oxaloacetate, C. a-ketoglutarate, D. Fumarate', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Transamination of aspaate leads directly to the formation of oxaloacetate, and a variety of compounds that are metabolized to yield propionyl CoA, which can be carboxylated and isomerized to succinyl CoA are also impoant anaplerotic substrates.Ref: Harper&;s Biochemistry; 30th edition; Chapter 16; The Citric Acid Cycle: The Central Pathway of Carbohydrate, Lipid & Amino Acid Metabolism', 'role': 'assistant'}]