This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'All are true about blood coagulation except? \nSelect and explain. \nA. Intrinsic pathway can be activated in vitro., B. Extrinsic pathway is activated by contact of plasma with negatively charged surfaces., C. Calcium is very important for coagulation., D. Factor X is a part of both intrinsic and extrinsic pathway.', 'role': 'user'}, {'content': 'Answer: D \nExplanation: • Ataxia telangiectasiais an autosomal recessive condition.\n• Patients have increased sensitivity to x-ray-induced chromosome abnormalities.\n• Characterized by an ataxic-dyskinetic syndrome beginning in early childhood, caused by neuronal degeneration predominantly in the cerebellum, the subsequent development of telangiectasias in the conjunctiva and skin, and immunodeficiency.\n• The nuclei of cells in many organs (e.g., Schwann cells in dorsal root ganglia and peripheral nerves, endothelial cells as well as pituicytes) show a bizarre enlargement of the cell nucleus and are referred to as amphicytes.\n• The lymph nodes, thymus, and gonads are hypoplastic.\n• Clinical features include recurrent sinopulmonary infections and unsteadiness in walking.\n• Increased risk of development of lymphoid malignant disease (T-cell leukemia and lymphoma)\nAll other options are autosomal dominant conditions.', 'role': 'assistant'}]