This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Disorder of Metabolism & Connective Tissue, Subject name: Medicine
[{'content': "What is the most likely diagnosis in a patient with generalized weakness and this finding? \nSelect and explain. \nA. Lichen planus pigmentosus, B. Smoker's melanosis, C. Cushing's disease, D. Diffuse melanosis cutis", 'role': 'user'}, {'content': 'Answer: D \nExplanation: Answer D. Diffuse melanosis cutisDiffuse melanosis cutis is the correct answer. It is a rare presentation of malignant melanoma with progressive discoloration of the skin. Diffuse melanosis cutis is typically associated with poor prognosis.', 'role': 'assistant'}]