This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
[{'content': 'Massage and the application of liniments to painful areas in the body relieves pain due to \nSelect and explain. \nA. Stimulation of endogenous analgesic system, B. Release of endorphins by the first order neurons in the brain stem, C. Release of glutamate and substance P in the spinal cord, D. Inhibition by large myelinated afferent fibres', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Massage and liniments application causes a tactile stimulus which is transmitted by Aβ fibers which are large myelinated fibers. This causes stimulation of enkephalinergic inhibitory interneurons through the collaterals, thus inhibiting the pain sensation through the spinothalamic tract.', 'role': 'assistant'}]