This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.V.S, Subject name: Pharmacology
[{'content': 'Glyceryl trinitrate is given by sublingual route because of: \nSelect and explain. \nA. Short t1/2 in plasma, B. High hepatic first pass metabolism, C. High bioavailability by oral route, D. Extensive protein binding', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans. (B) High hepatic first pass metabolism(Ref: KDT 8th/e p588)Main advantage of sublingual route of drug administration is that liver is bypassed and drugs with high first pass metabolism are absorbed directly into systemic circulation.', 'role': 'assistant'}]