This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Which of the following tumours have an increased elevation of placental alkaline phosphatase in the serum as well as a positive immunohistochemical staining for placental alkaline phosphatase - \nSelect and explain. \nA. Seminoma, B. Hepatoblastoma, C. Hepatocellular carcinoma, D. Peripheral neuroectodermal tumour', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Alkaline phosphatase - There are four major sources of Alkaline phosphatase in the body. These are:-\n\nLiver\xa0\xa0\xa0\xa0\xa0\xa0\xa0\nBone \xa0 \xa0\nIntestine\nPlacenta\n\nSo the normal serum alkaline phosphatase consists of 4 isoenzymes secreted from the above-mentioned sites.\nPlacental alkaline phosphatase is elevated in the following conditions -\n(a)\xa0Seminoma \xa0\n(b)\xa0Choriocarcinoma\n(c)\xa0Third trimester of pregnancy\nAbout other options -\nIn liver diseases and hepatocellular carcinoma the alkaline phosphatase elevated is of liver origin. Similarly the alkaline phosphatase elevated in bony diseases is due to some pathology in bone.', 'role': 'assistant'}]