This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cirrhosis, Subject name: Medicine
[{'content': 'Antibiotic of choice in cirrhotic patient to prevent encephalopathy: \nSelect and explain. \nA. Neomycin, B. Ampicillin, C. Metronidazole, D. Rifaximin', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Treatment of hepatic encephalopathy 1. Correct precipitating factors 2. Use lactulose- results in colonic acidification. 2. Poorly absorbed antibiotics- neomycin and metronidazole. More recently, rifaximin at 550 mg twice daily has been very effective in treating encephalopathy without the known side effects of neomycin or metronidazole.', 'role': 'assistant'}]