This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'L.E. Cell phenomenon in peripheral blood is seen in: \nSelect and explain. \nA. Rheumatic heart disease, B. Infective endocarditis, C. Ischemic heart disease, D. Systemic Lupus Erythernatosus', 'role': 'user'}, {'content': 'Answer: D \nExplanation: The addition of blood serum from a person under suspicion to the buffy coat of normal blood is the basis for L.E .cell phenomenon. If the patient is L.E. -we, then typical "LE" Cell develop. The cell consists of rosette of neutrophils surrounding a pale nuclear mass, derived from a Lymphocyte.', 'role': 'assistant'}]