This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: TCA Cycle, Subject name: Biochemistry
[{'content': 'All of the following are intermediates of TCA cycle, except : \nSelect and explain. \nA. Malonate, B. alpha -ketoglutarate, C. Succinate, D. Fumarate', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. a) Malonate is not an intermediate of TCA cycle Malonate Malate competitive inhibitor of succinate dehydrogenase intermediate in TCA cycle. TCA cycle intermediates are Citrate, Isocitrate, a-ketoglutarate, succinyl-CoA, Succinate, Fumarate, Malate, oxaloacetate. Acetyl-CoA is completely oxidised Oxaloacetate is regenerated.', 'role': 'assistant'}]