This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anatomy of skin, Subject name: Dental
[{'content': 'Collagen 17 is \nSelect and explain. \nA. Hemi-desmosome BPAG1, B. Hemi-desmosome BPAG2, C. Anchoring filaments, D. Anchoring fibrils', 'role': 'user'}, {'content': 'Answer: B \nExplanation: INFERIOR POION OF BASAL KERATINOCYTE Hemidesmosome (HD):- * Appears as thickened area interspersed along plasma membrane of basal keratinocyte; provides attachment between basal keratinocyte and extracellular matrix. * Composed of following macromolecules: BPAG1, BPAG2, integrin, and plectin . * Tonofilaments (or keratin filaments) inse into hemidesmosomes . BPAG1 (230 kDa) :- * Intracellular glycoprotein in plakin family which is associated with the cytoplasmic plaque domain of hemidesmosomes; promotes adhesion of intermediate filaments with plasma membrane (likely binds or anchors filaments to HD). BPAG2 (180kDa, Collagen XVII) :- * Transmembrane (mainly extracellular) protein belonging to collagen family; interacts with BPAG1, b4 integrin, and plectin. Ref:- Sima Jain; pg num:- 7', 'role': 'assistant'}]