This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Biguanides acts by following except - \nSelect and explain. \nA. |Insulin release from pancreas, B. | Glycolysis, C. | Gluconeogenesis, D. | Insulin binding to its receptors', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., | insulin release from pancreash Biguanides acts by : o Suppress hepatic gluconeogenesis and glucose output from liver major action. o Enhance insulin mediated glucose disposal in muscle and fat (Increased peripheral utilization of glucose) by enhancing GLUT-I transpo from intracellular site to plasma membrane. o Retad intestinal absorption of glucose. o Promote peripheral glucose utilization by enhancing anaerobic glycolysis.", 'role': 'assistant'}]