This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Breast, Subject name: Pathology
[{'content': "Type of DCIS resulting in palpable abnormality \nSelect and explain. \nA. Comedocarcinoma, B. Non comedo DCIS, C. Paget's disease, D. None", 'role': 'user'}, {'content': 'Answer: C \nExplanation: Paget disease of the nipple is caused by the extension of DCIS up the lactiferous ducts and into the contiguous skin of the nipple, producing a unilateral crusting exudate over the nipple and areolar skin. In almost all cases, an underlying carcinoma is present, and approximately 50% of the time this carcinoma is invasive. Prognosis is based on the underlying carcinoma and is not affected by the presence of Paget disease ref : Robbins Basic Pathology, 9E,page-710', 'role': 'assistant'}]