This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'The risk factor in cholangiocarcinoma \nSelect and explain. \nA. Pancreatitis, B. Ulcerave coltis, C. Pyelonephritis, D. Caroli disease', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Cholangiocarcinoma is a malignancy of the biliary tree, arising from bile ducts within or outside the liver,\no Risk factors All risk factors for cholangiocarcinomas cause chronic inammation and cholestasis,\nwhich presumably promote the occurrence of somatic mutations or epigenetic alterations in cholangiocytes. Primary sclerosing cholangitis.\nHepatolithiasis. Congenital bro-polycystic disease of the biliary system (Caroli disease, choledochal cyst). Hepatitis B and C. Exposure to thorotrast.\nOpisthorchissinensis and clonorchiasis infection', 'role': 'assistant'}]