This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Anatomy
[{'content': 'Cell which does not migrate from the base of the crypt to ends of villi is: \nSelect and explain. \nA. Enterocyte, B. Endocrine cell, C. Paneth cell, D. Goblet cell', 'role': 'user'}, {'content': 'Answer: C \nExplanation: C i.e. Paneth cells - Foamy appearance or frothy cytoplasm is a feature associated with presence of lipid / mucinous material in the cell cytoplasm. It is seen in mucous secreting goblet cells or lipid phagocytizing macrophage eg Touton giant cell (but not in paneth cells).- Paneth (zymogen) cells are rich in zinc, rough endoplasmic reticulum (RER) and secretory granules containing lysozyme, defensins or cryptidins such as TNF-aQ. It exceptionally migrate towards the base of crypt of Lieberkuhn instead of going towards the tip of villi.', 'role': 'assistant'}]