This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'Which of the following is the commonest cause of salt wasting nephropathy? \nSelect and explain. \nA. Analgesic (NSAID) misuse, B. Amyloidosis, C. Grommets disease, D. SLE', 'role': 'user'}, {'content': 'Answer: A \nExplanation: NSAIDS can cause tubal interstitial disease and hence impair the urine concentrating ability of the kidney. Patients with analgesic nephropathy have predominantly tubulomedullary dysfunction characterized by impaired concentrating ability, acidification defects and occasionally a salt-losing state. Proteinuria tends to be low to moderate in quantity which is typically a mixture of glomerular and tubular in origin.', 'role': 'assistant'}]