This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Which of these is a conservative mutator \nSelect and explain. \nA. Glutamic acid-glutamine, B. Histidine-glycine, C. Alanine-leucine, D. Arginine-aspartic acid', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Conserved mutation means altered AA has same properties of original AA. e.g. glutamic acid to aspartic acid (both acidic) or alanine to leucine (both aliphatic).', 'role': 'assistant'}]