This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
[{'content': 'Action of Papain on an IgG molecule produces? \nSelect and explain. \nA. 2 Fc fragments & 1 Fab fragment, B. 1 Fc fragment & 2 Fab fragments, C. 2 Fc fragments & 2 Fab fragments, D. 1 Fc fragment & 1 Fab fragment', 'role': 'user'}, {'content': "Answer: B \nExplanation: 1 Fc fragment & 2 Fab fragments REF: Jawetz, Melnick, & Adelberg's Medical Microbiology, 24TH edition Chapter 44 If an antibody molecule is treated with a proteolytic enzyme (eg, Papain), peptide bonds in the hinge region are broken. This breakage produces two identical Fab fragments, which carry the antigen-binding sites, and one Fc fragment, which is involved in placental transfer, complement fixation, attachment for various cells, and other biologic activities.", 'role': 'assistant'}]