This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Lipid Oxidation and Synthesis, Subject name: Biochemistry
[{'content': 'Sandhoffs disease is d/t absence of which enzyme? \nSelect and explain. \nA. Beta-hexosaminidase, B. Beta-glucuronibase, C. Arylsulphatase, D. Alpha galactosidase', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e.. Beta-hexosaminidase DiseaseEnzyme deficiencyLipid accumulatedTay-sach diseaseHexosaminidase AGM2 gangliosideSandoff diseaseHexosaminidase BGM2 gangliosideNiemann-Pick diseaseSphingomyelinaseSphingomvelineFarber's diseaseCeramidaseAcyl-sphingosine (ceramide)Fabry's diseasea-galactosidaseGlobotrisylceramideKrabbe's diseaseb-galactosidase (Galactosylceramidase)GaiactosylceramideGaucher's diseaseb-glucosidase (glucocerebrosidase)GlucosylceramideMetachromatic leukodystrophyArylsulfatase A3-Sulfogalactosylceramide", 'role': 'assistant'}]