This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Fatty acid and synthesis, Subject name: Biochemistry
[{'content': 'Which of the following is the allosteric activator of Acetyl-CoA carboxylase? \nSelect and explain. \nA. Malonyl-CoA, B. Acetyl-CoA, C. Citrate, D. Biotin', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Acetyl-CoA carboxylase is active when it is polymerized. Citrate promotes its polymerization. Citrate is an indicator of high-energy status. Palmitoyl-CoA inhibits its polymerization.', 'role': 'assistant'}]