This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Methionine and Cysteine details, Subject name: Biochemistry
[{'content': 'The protein defective in cystinosis is responsible for \nSelect and explain. \nA. Absorption of cysteine from intestine, B. Absorption of cysteine from renal tubules, C. Efflux cysteine from endoplasmic reticulum, D. Efflux of cysteine from lysosome', 'role': 'user'}, {'content': "Answer: D \nExplanation: The protein defective in cystinosis is Cystinosin CTNS (lysosomal efflux). Clinical features:- Renal Fanconi's syndrome & Renal failure Rickets Photophobia Hypotonia Do not confuse cystinuria and cystinosis. Cystinosis is a lysosomal storage disease due defective transpo of cystine out of lysosomes.", 'role': 'assistant'}]