This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Anaesthesia
[{'content': 'Pupil fails to dilate by giving cocaine in – \nSelect and explain. \nA. Central sympathetic paralysis, B. Central parasympathetic paralysis, C. Peripheral parasympathetic paralysis, D. Peripheral sympathetic paralysis.', 'role': 'user'}, {'content': 'Answer: D \nExplanation: In periphery cocaine blocks the uptake of Adrenaline and Noradrenaline in Adrenergic nerve ending resulting in higher concentration of sympathetic neurotransmitters (Sympathomimetic effect) :\nThe peripheral sympathomimetic action of cocaine produces following effect :\n\n\nMydriasis\nRise in B.P.\nLocal vasoconstriction\nTachycardia\n\n\nTherefore if the peripheral sympathetic system is paralysed it will lead to reverse of the above mentioned actions.', 'role': 'assistant'}]