This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pediatrics
[{'content': 'Common presentations of juvenile Hypothyroidism \nSelect and explain. \nA. Growth retardation, B. Mental retardation within 2 years, C. Delayed pubey, D. Umbilical Hernia', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Most common presentation of juvenile hypothyroidism is growth retardation. others include delayed skeletal maturation,delayed dental development,delayed pubey, myopathy and pseudohyperophy,enlarged sella,pseudomotor cerebri. Usually due to hormonal synthesis defect such as TPO or to c -erb A mutation PE : goiter, delayed maturation, testicular enlargement/precocious menarche NOT usually MR- recovery is general rule with thyroxine Reference: OP Ghai ,essential paediatrics ,8 th edition.page no 517', 'role': 'assistant'}]