This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Cleft lip, polydactyly, Holoprosencephaly are characteristic feature of? \nSelect and explain. \nA. Down syndrome, B. Edward syndrome, C. Patau syndrome, D. Turners syndrome', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Patau syndrome is due to trisomy 13.', 'role': 'assistant'}]