This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nervous system, Subject name: Physiology
[{'content': 'Leptin is decreased in all except \nSelect and explain. \nA. Androgen, B. Exercise, C. Obesity, D. Starvation', 'role': 'user'}, {'content': 'Answer: C \nExplanation: In obesity, despite the presence of elevated leptin concentrations, which should reduce food intake and body fat, obese patients appear to be insensitive or resistant to leptin.', 'role': 'assistant'}]