This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Orthopaedics
[{'content': 'Management plan for osteogenic sarcoma of the lower end of femur must include - \nSelect and explain. \nA. Radiotherapy, amputation, chemotherapy, B. Surgery alone, C. Chemotherapy + Limb Salvage Surgery + Chemotherapy, D. Chemotherapy + Radiotherapy', 'role': 'user'}, {'content': 'Answer: C \nExplanation: The usual protocol is : -\n\n\nFirst give neoadjuvant chemotherapy (Pre-operative chemotherapy).\nNeo-adjuvant chemotherapy is followed by surgery : - This may be limb salvage surgery (most of the time) or amputation depending on the situation.\nSurgery is followed by postoperative chemotherapy.', 'role': 'assistant'}]