This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Breast, Subject name: Pathology
[{'content': 'A female patient presented with a firm mass of 2 x 2 cms in the upper outer quadrant of the breast. She gives a family history of ovarian carcinoma. The investigation that needs to be done to assess for mutation is : \nSelect and explain. \nA. p53, B. BRCA-2, C. Her 2/Neu gene, D. C-myc gene', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans. is \'b\' BRCA 2 "In women with hereditary breast - ovarian cancer, two susceptibility loci have been identified:BRCA -1 - located on chromosome 17 andBRCA - 2 - located on chromosome 13" - Harrison, 15/e, p620', 'role': 'assistant'}]