This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: New Born Infants, Subject name: Pediatrics
[{'content': 'Drug of choice for withdrawal syndrome in a neonate due to maternal opiate addiction is- \nSelect and explain. \nA. Methadone, B. Buprenorphine, C. Phenobarbital, D. Self limiting process, so only observation.', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Methadone * Drug withdrawal is a self-limiting process.* However, withdrawal from sedative-hypnotic drugs or narcotics can be lifethreatening.* Indications for drug treatment include seizures, poor feeding, diarrhea, excessive vomiting, inability to sleep, and fever.Management of Opiate withdrawal* Care in a quiet environment with reduction of external stimuli and swaddling.* Pharmacologic treatment of heroin and methadone withdrawal requires opiate replacement during the 1st wk or 2 of life.* Methadone is the drug of choice, but oral or sublingual buprenorphine is an alternate approach.* Adjunct treatment with phenobarbital or clonidine is rarely necessary.* Methadone withdrawal may require larger amounts of medication for longer periods to control clinical manifestations than are needed for heroin withdrawal.", 'role': 'assistant'}]