This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Surgery
[{'content': 'Treatment of squamous cell carcinoma of anal canal not involving the deeper structures include \nSelect and explain. \nA. Abdomino pereneal resection, B. Wide local excision + Radiotherapy, C. Wide local excision + Chemoradiation, D. Chemoradiation', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Anal cancer # Uncommon tumour, which is usually a squamous cell carcinoma # Associated with HPV # More prevalent in patients with HIV infection # May affect the anal verge or anal canal # Lymphatic spread is to the inguinal lymph nodes # Treatment is by chemoradiotherapy in the first instance # Major ablative surgery is required if the above fails Ref: Bailey & Love&;s Sho Practice of Surgery,E25,Page-1269', 'role': 'assistant'}]