This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Mechanism of action of azoles is \nSelect and explain. \nA. By altering membrane permeability, B. By blocking nucleic acid synthesis, C. By disrupting microtubules function, D. By inhibiting cell wall synthesis', 'role': 'user'}, {'content': 'Answer: A \nExplanation: According to the mechanism of action these can be classified as\xa0\n\nDrugs altering membrane permeability\xa0\n\n- Azoles\xa0\n- Triazoles e.g. Fluconazole, itraconazole, voriconazole, terconazole, posaconazole.\n- Imidazoles e.g. Ketoconazole, miconazole, clotrimazole, econazole, butoconazole, oxiconazole, sertaconazole, sulconazole.\xa0\n- Terbinafine, butenafine, naftifine.\n- Polyenes e.g. Amphotericin B, nystatin, hamycin\xa0\n\nDrugs blocking nucleic acid synthesis e.g. Flucytosine\xa0\nDrugs disrupting microtubule function e.g. Griseofulvin\xa0\nDrugs inhibiting cell wall synthesis e.g. Caspofungin, nikkomycin.', 'role': 'assistant'}]