This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Obstructive Lung Disease, Subject name: Pathology
[{'content': 'All of the following statement are true regarding centriacinar emphysema, except: \nSelect and explain. \nA. Most common type of emphysema, B. Respiratory bronchiole are affected and distal alveoli are spared, C. Common and more severe in lower lobes, D. Associated with smoking', 'role': 'user'}, {'content': "Answer: C \nExplanation: Centri-acinar Emphysema C's Commonest type of emphysema Central poion of acinus involved. Cigarette smoking It is common and more severe in UPPER lobe", 'role': 'assistant'}]