This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti-Fungal Drugs, Subject name: Pharmacology
[{'content': 'Mechanism of action of Triazoles:- \nSelect and explain. \nA. Inhibits ergosterol biosynthesis, B. Inhibits tubulin, C. Inhibits glucan synthesis, D. Inhibits cell wall synthesis', 'role': 'user'}, {'content': "Answer: A \nExplanation: The azoles act by inhibiting fungal cytochrome P450 enzyme 'lanosterol 14-demethylase' and thus impair ergosterol synthesis. These are presently the most extensively used antifungal drugs. Mechanism of action of other antifungal drugs: Polyene (Amphotericin B/Nystatin): Binds to ergosterol and creates pores. 5 Flucytosine : DNA polymerase inhibitor. Allylamine (Terbinafine, Butenafine, Naftifine): Inhibit enzyme squalene epoxidase. Griseofulvin : Act mitotic spindle Echinocandin (Caspofungin): Inhibit Beta 1-3", 'role': 'assistant'}]