This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Childhood tumors, Subject name: Pediatrics
[{'content': 'Non specific esterase is positive in all the categories of AML except \nSelect and explain. \nA. M3, B. M4, C. M5, D. M6', 'role': 'user'}, {'content': "Answer: D \nExplanation: Non specific esterase on cytochemistry is strongly positive in M5(acute monocytic leukemia- Schilling type) and M4(acute myelomonocytic leukemia -Naegeli type) which have monocytic component.It is also positive in M3(acute promyelocytic leukemia).But non specific esterase is negative in M6(acute erythroleukemia-Di Guglielmo's syndrome),which shows positive for Periodic acid-Schiff. Reference:Textbook of pathology-Harsh Mohan,6th edition,page no:362.", 'role': 'assistant'}]