This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Musculoskeletal  disorders, Subject name: Pediatrics
[{'content': 'Which of the following is false regarding brittle bone disease? \nSelect and explain. \nA. It is caused by defects in type 2 collagen, B. Predominantly autosomal-dominant inheritance is seen, C. Blue sclerae and deafness may be associated, D. Bisphosphonates are useful in the treatment', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Brittle bone disease is another name for osteogenesis imperfecta (OI). It is due to defects in type 1 collagen, not type 2 collagen. There are 12 types of OI, with type 1 being the most common. Triad of fragile bones, blue sclera and deafness is known as van der Hoeve syndrome. Treatment includes bisphosphonate therapy and ohopedic rehabilitation. Ref: Nelson textbook of pediatrics 21st edition pgno: 3737', 'role': 'assistant'}]