This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'Esophageal adenocarcinoma is predisposed by \nSelect and explain. \nA. Achalasia, B. Scleroderma, C. Corrossive intake, D. All', 'role': 'user'}, {'content': "Answer: B \nExplanation: Answer is B (Scleroderma) Barret's esophagus is the characteristic risk factor for adenocarcinoma esophagus. Scleroderma also increases the risk of esophageal adenocarcinoma perhaps through the development of Barret's esophagus as the collagen deposits in the distal esophagus cause LES dysfunction. Risk factors for esophageal adenocarcinoma (Current Gastroenterology) Barrets esophagus Gastroesophageal Reflux Disease (GERD) Scleroderma Smoking Alcohol History of colon cancer Medications Long term use (> 5 years) of Theophylline & agonists.", 'role': 'assistant'}]