This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'The following drugs are used for prophylaxis of migraine except \nSelect and explain. \nA. Valproate, B. Topiramate, C. Meperidine, D. Metoprolol', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Meperidine is opioid analgesic which is avoided in migraine.', 'role': 'assistant'}]