This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Urethra and penis, Subject name: Surgery
[{'content': 'Buschke - Lowenstein tumor is: \nSelect and explain. \nA. Malignant transformation in plantar wa, B. Malignant transformation in anogenital wa, C. Malignant transformation in common wa, D. Malignant transformation in seborrheic wa', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Bushke - Lowenstein tumour (verrucous carcinoma): Tumor destroy adjacent tissue by compression, No metastasis usually (Locally malignant) Verrucous carcinoma is a locally aggressive form of condyloma acuminata. Wide local excision is TOC Topical immunomodulators- Imiquimod (Aldara)can be given Very large lesions may respond to external beam radiation, but resection is almost always required.', 'role': 'assistant'}]