This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Orthopaedics
[{'content': 'True about Bone metastasis -a) 5% bone metastasis are symptomaticb) Higher serum levels of alkaline phosphatasec) Most common secondary in female is breastd) Prostate produce osteosclerotic lesion \nSelect and explain. \nA. abc, B. acd, C. ac, D. bcd', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Most common tumor producing bone metastasis in females is breast carcinoma and in males is prostatic carcinoma.\nProstatic carcinoma produces osteoblastic (osteosclerotic) lesions.\nOsteoblastic lesions are associated with higher serum levels of alkaline phosphatase (reflecting high activity of osteoblasts).', 'role': 'assistant'}]