This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'A  20-year-old  patient  weighing  60  kg  has  to  be  prescribed  an  antiepileptic  drug  (available\nas 200 and 400 mg tablets) for generalized tonic-clonic seizures. The pharmacokinetic parameters\nand  therapeutic  plasma  concentration  of  the  selected  drug  are:\nTarget  steady-state  plasma  concentration  (Cpss) –  6  mg/L\nOral  bioavailability  (F) –  70%\nVolume  of  distribution  (V) –  1.4  L/kg\nClearance  (CL) –  80  ml/hr/kg\nPlasma  half  life  (t½) –  15  hours\nWhat should be the loading dose and the daily maintenance dose of the drug for this patient? \nSelect and explain. \nA. 720 and 984 mg respectively, B. 984 and 720 mg respectively, C. 450 and 720 mg respectively, D. 884 and 984 mg respectively', 'role': 'user'}, {'content': 'Answer: A \nExplanation: The total volume of distribution and total body clearance for this patients has to be calculated first.', 'role': 'assistant'}]