This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology and breast, Subject name: Surgery
[{'content': 'Consider the following statements regarding paget&;s disease of the breast \nSelect and explain. \nA. It is a malignant disease, B. Diagnosis can be established by scrape cytology, C. Lymph nodes involvement is an associated clinical feature, D. Treatment of choice is simple mastectomy', 'role': 'user'}, {'content': "Answer: D \nExplanation: .In Paget's disease, there is a hard nodule just underneath the areola, which later ulcerates and causes destruction of nipple. Histologically, it contains large, ovoid, clear Paget's cells with malignant features.* Total (simple) mastectomy: Along with the tumour, entire breast, areola, nipple, skin over the breast, including axillary tail are removed. There is no axillary dissection. Often the patient is subjected to radiotherapy later (External) to axilla. ref:SRB&;s manual of surgery,ed 3,pg no 482", 'role': 'assistant'}]