This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'In argininosuccinase deficiency, what should be supplemented to continue the urea cycle ? \nSelect and explain. \nA. Aspaate, B. Arginine, C. Citrullin, D. Argininosuccinate', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Argininosuccinase (argininosuccinate lyase) catalyses the cleavage of arginiosuccinate into arginine and fumarate. o Thus, in argininosuccinase deficiency arginine cannot be produced. Supplementation with arginine base helps replenish this amino acid.', 'role': 'assistant'}]