This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous (Bio-Chemistry), Subject name: Biochemistry
[{'content': "Taysach's disease is due to the deficiency of \nSelect and explain. \nA. Hexosaminidase, B. Lysozomal enzyme, C. Galactocerebroside, D. Ceramidase", 'role': 'user'}, {'content': 'Answer: A \nExplanation: (A) Hexosaminidase # Tay-Sachs disease (TSD, GM2 gangliosidosis, Hexosaminidase A deficiency or Sphingolipidosis) is a genetic disorder, fatal in its most common variant known as Infantile Tay-Sachs disease. TSD is inherited in an autosomal recessive pattern.> Disease occurs when harmful quantities of a fatty acid derivative called a ganglioside accumulate in the nerve cells of the brain.> Gangliosides are lipids, components of cellular membranes, and the ganglioside GM2, implicated in Tay-Sachs disease, is especially common in the nervous tissue of the brain.', 'role': 'assistant'}]