This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Medicine
[{'content': 'All are True about hepatorenal syndrome except - \nSelect and explain. \nA. Seen in advanced stage of cirrhosis, B. Type II has more serious prognosis than type I, C. Due to intense hypoperfusion of kidney, D. Functional renal failure without renal pathology', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Hepatorenal syndrome - It is functional renal failure without renal pathology that occurs in about 10% of patients with advanced cirrhosis or acute liver failure. There are marked disturbances in aerial renal circulation in patients with HRS Increase in vascular resistance(renal vasoconstriction ) accompanied by decrease in systemic vascular resistance . The reason for renal vasoconstriction is multifactorial and poorly understood. It is of two types - HRS1-it is characterized by proggressive impairment in renal function and significant reduction in creatinine clearance within 2 weeks of presentation . HRS2-reduction in GFR and increase in creatinine ,but it is stable and has better outcome than type 1 Currently, patients are treated with midodrine (alpha agonist) ,octreotide and intravenous albumin. The best therapy for HRS IS liver transplantation.(type 1or 2) Ref:Harrison 20 th edition pg no 2413', 'role': 'assistant'}]