This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Medicine
[{'content': "The presence of PAS-positive macrophages in the small intestine is a hallmark of \nSelect and explain. \nA. Whipple's disease, B. Crohn's disease, C. Celiac disease, D. Tropical sprue", 'role': 'user'}, {'content': "Answer: A \nExplanation: Whipple's disease is a chronic multisystemic disease associated with diarrhoea, steatorrhea, weight loss, ahralgia, and central nervous system (CNS) and cardiac problems; it is caused by the bacterium Tropheryma whipplei. Until the identification of T. whipplei by polymerase chain reaction, the hallmark of Whipple's disease had been the presence of PAS-positive macrophages in the small intestine and other organs with evidence of diseaseThe treatment for Whipple's disease is double-strength trimethoprim-sulfamethoxazole for ~1 year. Harrison 19e pg: 1945", 'role': 'assistant'}]