This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Medicine
[{'content': "Cushing's disease presents with- \nSelect and explain. \nA. IncreasedACTH and increased Coisol, B. Decreased ACTH and decreased Coisol, C. IncreasedACTH and decreased Coisol, D. Increased catecholamines", 'role': 'user'}, {'content': 'Answer: A \nExplanation: increased production of coisol by adrenals and bilateral adrenal hyperplasia due to hyper secretion of pituitary ACTH( Harrison 17 pg 2255)', 'role': 'assistant'}]