This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': 'Causes of female pseudohermaphroditism – \nSelect and explain. \nA. 17–alpha hydroxylase deficiency, B. 21–alpha hydroxylase deficiency, C. Mixed gonadal dysgenesis, D. All of the above', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ambiguous genitalia (Hermaphroditism)\n\nAmbiguous genitalia is defined as a discrepancy between the external genitals and internal gonads.\nThey can be categorized : -\n\n\nFemale pseudohermaphroditism\nMale pseudohermaphroditism\nTrue hermaphroditism\n\nFemale pseudohermaphroditism.\n\nGenotype is XX\nGonads are ovaries\nExternal genitalia is virilized (male differentiation).\nAs there is no Mullarian inhibiting factor, Mullerian duct develops into uterus tubes and ovary. But due to the presence of androgen external genitalia are virilized.\n\nCauses are:\n\nMaternal virilizing tumour → Arrhenoblastoma\n21 hydroxylase deficiency\n11 beta hydroxylase deficiency\nMaternal medications with androgen', 'role': 'assistant'}]