This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General anatomy, Subject name: Anatomy
[{'content': 'The following interleukin is characterically produced in a TH1 response \nSelect and explain. \nA. IL2, B. IL4, C. IL5, D. IL 10', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ref Robbins 7/e p198;8/e p195; 9/e p198 IL-2 has essential roles in key functions of the immune system, tolerance and immunity, primarily its direct effects on T cells. In the thymus, where T cells mature, it prevents autoimmune diseases by promoting the differentiation of ceain immature T cells into regulatory T cells, which suppress other T cells that are otherwise primed to attack normal healthy cells in the body. IL-2 enhances activation-induced cell death (AICD). IL-2 also promotes the differentiation of T cells into effector T cells and into memory T cells when the initial T cell is also stimulated by an antigen, thus helping the body fight off infections. Together with other polarizing cytokines, IL-2 stimulates naive CD4+ T cell differentiation into Th1 and Th2 lymphocytes while it impedes differentiation into Th17 and folicular Th lymphocytes', 'role': 'assistant'}]