This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
[{'content': 'E6 gene product of HPV causes malignance transformation by acting on ? \nSelect and explain. \nA. p53 gene, B. RAS gene, C. C-myc gene, D. N-myc gene', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., p-53 gene HPV selectively infects the epithelium of skin and mucous membrane and may immoalize the keratinocytes leading either asymptomatic infection, or was or neoplasia.Products of E-genes (E6, E7) are related to immoalization or malignant transformation of keratinocytes by interfering with p53 and Rb genes, respectively.", 'role': 'assistant'}]