This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': "A good prognostic feature in Hodgkin's disease is known as: \nSelect and explain. \nA. Clinical state, B. Histologic subtype, C. Age of the patients, D. Number of lymph node involvement", 'role': 'user'}, {'content': "Answer: A \nExplanation: (Clinical state): Ref: 6790-R (459-Basicpathology 8th)HODGKIN'S DISEASE* With current treatment protocols, tumor stage rather than histologic type is the most important prognostic variables (690-R)* The staging evaluation for a patients with Hodgkin's disease would typically include a careful history and physical examination (654-H)* Worst prognosis in older age, bulky disease, lymphocyte depletion or mixed cellularity. (459-CMDT-06)Clinical differences Between Hodgkins and Non-Hodgkins LymphomaHodgkin LymphomasNon-Hodgkin Lymphoma* Most often localized to a single axial group of nodes (cervical, mediastinal, para aortic)* More frequent involvement of multiple peripheral nodes* Orderely spread by contiguity* Moncontiguous spread* Mesenteric nodes and Waldeyer ring rarely involved* Waldeyer ring and mesenteric nodes commonly involved* Extranodal involvement uncommon* Extranodal involvement common", 'role': 'assistant'}]