This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy: General Principles, Subject name: Pharmacology
[{'content': 'Mechanism of action of protease inhibitors is: \nSelect and explain. \nA. Prevents maturation of new viral particles, B. Prevents translation of viral RNA, C. Causes apoptosis of the affected cells, D. Inhibits proviral RNA synthesis', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. (A) Prevents maturation of new viral particles(Ref: KDT 7/e p809)Function of protease enzyme in HIV is to break inactive polyproteins to functional components. This post-translational modification is required for maturation of new viral particles. Protease inhibitors like atazanavir inhibit this step.', 'role': 'assistant'}]