This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Gastrointestinal System, Subject name: Physiology
[{'content': 'Which of the following inhibits both gastric acid secretion and motility? \nSelect and explain. \nA. Vasoactive intestinal polypeptide (VIP), B. Gastric inhibitory peptide (GIP), C. Somatostatin, D. Ghrelin', 'role': 'user'}, {'content': 'Answer: B \nExplanation: G.I.P Secretion + glucose /fat in duodenum, in large doses it inhibits gastric secretion and motility V.I.P -They are inhibitory to the smooth muscles of the intestines. -It causes smooth muscle relaxation in the GIT --> decreases the motility Somatostatin: -Central mechanism of inhibition of gastric acid secretion. -No role in inhibition of gastric motility or gastric emptying Ghrelin: -Increases GH release from the pituitary. -Increases appetite by stimulating neuropeptide Y (NPY) in the feeding centers of the lateral hypothalamus. -Decreases the breakdown of fat and increases gastric motility and acid secretion. -Thus, ghrelin has effect on both gastric motility and secretion; it increases both.', 'role': 'assistant'}]