This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'The worst prognosis for renal cell carcinoma is \nSelect and explain. \nA. Vascular invasion, B. Associated with hypercalcemia, C. Presence of Hematuria, D. Size more than 5 cm.', 'role': 'user'}, {'content': 'Answer: A \nExplanation: None', 'role': 'assistant'}]