This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General anatomy, Subject name: Anatomy
[{'content': 'Which of the following is an anti apoptotic gene \nSelect and explain. \nA. C_myc, B. P53, C. Bcl_2, D. Bax', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ref : Harrison 17/e p506 ; Robbins 9/e p19 synthesize anti-apoptotic members of the Bcl-2 family, the two main ones of which are Bcl-2 itself and Bcl-xL. These proteins antagonize Bax and Bak, and thus limit the escape of the mitochondrial pro-apoptotic proteins. Cells deprived of growth factors not only activate the pro-apoptotic Bax and Bak but also show reduced levels of Bcl-2 and Bcl-xL, thus fuher tilting the balance toward death. The mitochondrial pathway seems to be the pathway that is responsible for apoptosis in most situa- tions', 'role': 'assistant'}]