This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Adrenal Gland, Subject name: Pathology
[{'content': "All of the following statements are true regarding craniopharyngioma, except: \nSelect and explain. \nA. Origin from Rathke's pouch, B. Aggressive malignant tumor, C. Papillary variant of the tumour is associated with BRAF V600E mutation, D. Adamantinomatous variant is associated with abnormality in WNT/CTNNB1 (b-catenin) pathway", 'role': 'user'}, {'content': "Answer: B \nExplanation: Craniopharyngioma Arise from vestigial remnants of Rathke's pouch. Slow-growing benign tumors Accounts 1% to 5% of intracranial tumors. Minority of these lesions occurs within sella, but most are suprasellar with/ without intrasellar extension. Adamantinomatous craniopharyngioma - Abnormalities of WNT signaling pathway, activating mutations of gene encoding b-catenin. Papillary subtype is characterized by activating mutations of the BRAF oncogene at codon 600 (V600E).", 'role': 'assistant'}]