This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Lab Investigations, Subject name: Microbiology
[{'content': "All of the following are true about Methicillin resistance in MRSA, except- \nSelect and explain. \nA. Resistance is produced as a result of altered PBP's, B. Resistance may be produced by hyperproduction of beta lactamase, C. Resistance is primarily mediated/transmitted plasmids, D. Resistance may be missed at incubation temperature of 370C during susceptibility testing", 'role': 'user'}, {'content': "Answer: C \nExplanation: Resistance in MRSA is chromosomally mediated (not plasmid mediated). Resistance is produced as a result of altered PBP's- mediated chromosomal mec A gene which codes for altered PBP- 2A. Resistance may be produced by hyperproduction of beta-lactamase Methicillin resistance is expressed more at 30degC than at 37degC. Therefore, resistance may be missed at incubation temperature at 37degC during susceptibility testing.", 'role': 'assistant'}]