This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'LE cell is seen in ? \nSelect and explain. \nA. Lupus erythmatosus, B. Lupus vulgaris, C. HNPCC, D. Medullary carcinoma of thyroid', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Lupus erythematousus In SLE, antinuclear antibodies (AN Ps) can not penetrate intact cells. However, nuclei are exposed, ANA can bind to them. In tissues, nuclei of damaged cells react with ANAs, lose their chromatin pattern, and become homogeneous, to produce lupus - erythematous (LE) bodies or hemotoxylin bodies. When these LE bodies are engulfed by phagocytic cells (neutrophil or macrophage/monocyte), the phagocytic cells are called LE cells.", 'role': 'assistant'}]