This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': "Poor wound healing in vitamin 'C' deficiency is due to all except - \nSelect and explain. \nA. Inhibition of collagen synthesis, B. Defective collagen synthesis, C. Defective post-translational modification of collagen, D. Defective hydroxylation", 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. is "a" Inhibition of collagen synthesisAscorbic acid (Vitamin C) is also called antiscorbutic factor. It is very heat labile, especially in basic medium. Ascorbic acid itself is an active form. Maximum amount of vitamin C is found in adrenal coex.Ascorbic acid functions as a reducing agent and scavanger of free radicals (antioxidant). Its major functions arevitamin C is essential for the conversion of procollagen to collagen, which is rich in hydroxyproline and hydroxylysine. Through collagen synthesis, it plays a role in the formation of matrix of bone, cailage, dentine and connective tissue.Vitamin C is required for post-translational modification by hydroxylation of proline and lysine residues conveing them into hydroxyproline and hydroxylysine.', 'role': 'assistant'}]