This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Thalassaemia major manifests in- \nSelect and explain. \nA. Childhood, B. Pubey, C. Adolescence, D. Middle age', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Childhood o Severe anemia manifests 6-9 months after bih, as hemoglobin synthesis switches from HbF to HbA.", 'role': 'assistant'}]