This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'In hyaline membrane disease, the pathology in the lung consists of - \nSelect and explain. \nA. Albumin and complement, B. Fibrin, C. Precipitated surfactant, D. Mucus', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Morphological changes in ARDS \n\nDiffuse alveolar damage is the characteristic histological manifestation of ARDS.\nIn the acute stage, the lungs are heavy, firm, red and boggy with congestion, interstitial and intra-alveolar edema.\nThe alveolar walls become lined with a waxy haline membrane.\nThe hyaline membrane consists of fibrin-rich edema fluid mixed with the cytoplasmic and lipid remnants of necrotic epithelial cells.\nResolution is unusual, more commonly, there is an organization of the fibrin exudate, with resultant intra-alveolar fibrosis.', 'role': 'assistant'}]