This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Fluroquinolone mechanism of action in gram positive organism is by ? \nSelect and explain. \nA. DNA gyrase, B. Topoisomerase II, C. Topoisomerase III, D. Topoisomerase IV', 'role': 'user'}, {'content': "Answer: D \nExplanation: Ans. is 'd' i.e., Topoisomerase IV Fluroquinolones Fluoroquinolones (including ciprofloxacin) inhibit DNA gyrase and topoisomerase IV. For gram negative bacteria, the primary target is DNA gyrase, while topoisomerase IV is inhibited in gram positive bacteria.", 'role': 'assistant'}]