This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'The hepatotoxic octapeptides of Amanita phalloides usually produce: \nSelect and explain. \nA. Massive hepatic necrosis, B. Centrilobular zonal necrosis, C. Peripoal injury, D. Granuloma formation in liver', 'role': 'user'}, {'content': "Answer: A \nExplanation: The hepatotoxic octapeptides of Amanita phalloides usually produce massive hepatic necrosis; the lethal dose of the toxin is 10 mg, the amount found in a single death cap mushroom. Ref: Harrison's Principles of Internal Medicine, 18th Edition, Page 2558.", 'role': 'assistant'}]