This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Pathology
[{'content': 'Prolonged prothrombin time is seen in ? \nSelect and explain. \nA. Haemophilia A, B. Haemophilia B, C. Thrombocytopenia, D. Factor VII deficiency', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Prothrombin time evaluates extrinsic factors and common pathway factors (factors 1,2,5,7,10).Prolongation of PT time occurs with deficiency of these factors. Haemophilia A is due to factor 8 deficiency, which is an intrinsic factor.So no PT prolongation Haemophilia B due to factor 9 deficiency. No PT Prolongation Thrombocytopenia due to decreased platelet number. so no PT prolongation . Factor 7 is an extrinsic factor .So its deficiency causes prolongation of PT Ref. Robbins and Cotran Pathologic basis of disease.South Asia Edition volume 1.page no.657,662,663 Harsh Mohan textbook of pathology 7th edition.Pg no.307', 'role': 'assistant'}]