This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous (Pharmacology), Subject name: Pharmacology
[{'content': 'A patient is taking ketoconazole for fungal infection develops cold for which he is prescribed terfenadine. Possible interaction between terfenadine and ketoconazole is \nSelect and explain. \nA. Ketoconazole decreases metabolism of terfenadine, B. Terfenadine increases levels of ketoconazole, C. Ketoconazole decreases levels of terfenadine, D. No interaction', 'role': 'user'}, {'content': 'Answer: A \nExplanation: (A) Ketoconazole decreases metabolism of terfenadine# Large amounts of Terfenadine reach systemic circulation if erythromycin, ketoconazole, clarithromycin are concurrently administered, as these drugs are P450 enzyme inhibitors.> Azithromycin, fluconazole have no effect & found to be safe.', 'role': 'assistant'}]