This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Resistance to methicllin is acquired by: \nSelect and explain. \nA. Increased B-lactamase production, B. Induction of channels that pump out the drug, C. Alteration in penicillin binding protein, D. Decreased absorption of drug in the gut', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Methicillin, Nefcillin, oxacillin are B lactamse resistant penicillins. Resistance can occur only if there is alteration of penicillin binding protein.', 'role': 'assistant'}]