This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Disorder of Metabolism & Connective Tissue, Subject name: Medicine
[{'content': 'Inheritance of familial hypercholesterolemia: \nSelect and explain. \nA. AR, B. AD, C. XR, D. XD', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ref: Harrison's Principles of Internal Medicine, 18th edition, page 3148Explanation:Familial hypercholesterolemia (FH):Homozygous FH is AD.one of the common single-gene disordersElevated LDL (500- lOOOmg/dL), normal TGCutaneous xanthomasPremature coronary artery diseaseEarly death in childrenHeterozygous FH . i in 500 populationLDL 200-400 mg/dlCAD in early ageTendon xanthomas, arcus lipidalisTreated with statins, cholesterol absorption inhibitor/bile acid sequestrumLDL apheresis needed rarely (See the following table)", 'role': 'assistant'}]