This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Physiology
[{'content': 'Which of the following is not seen during capacitation? \nSelect and explain. \nA. Increased permeability to calcium, B. Decreased permeability to calcium, C. Removal of cholesterol from acrosome, D. Increased motility', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Capacitation is the penultimate step in the maturation of mammalian spermatozoa and is required to render them competent to feilize an oocyte. This step is a biochemical event; the sperm move normally and look mature prior to capacitation. Ref: guyton and hall textbook of medical physiology 12 edition page number:651,652,653', 'role': 'assistant'}]