This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
[{'content': 'The granuloma is characterized by \nSelect and explain. \nA. Focal accumulation of activated macrophages, B. Collection of neutrophils, C. Newly formed vessels, D. Collection of eosinophils', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Granulomatous inflammation is a distinctive pattern of chronic inflammation characterized by aggregates of activated macrophages with scattered lymphocytes granuloma:-is an aggregation of macrophages surrounded by a collar of mononuclear cells principally lymphocytes Macrophages may get activated to form epithelioid cells Some of the cells may fuse together to form a bigger cell called a giant cell Older granulomas may have a rim of fibroblasts and connective tissue Common conditions resulting in granuloma formation with impoant features Tuberculosis Sarcoidosis (Non-caseating granuloma) Brucellosis Cat scratch disease (Stellate shaped or round granuloma) Syphilis (Gumma) Leprosy Inflammatory bowel disease ref pathology robbins 9th ed page 56', 'role': 'assistant'}]