This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Central Nervous system, Subject name: Pharmacology
[{'content': 'Which of the following has highest potential to cause metabolic syndrome? \nSelect and explain. \nA. Clozapine, B. Risperidone, C. Quetiapine, D. Aripiprazole', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Metabolic complication like weight gain, hyperlipidemia and precipitation of diabetes is a major limitation. Other given drugs donot cause metabolic syndrome. Ref KD TRIPATI 8TH ED.', 'role': 'assistant'}]