This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'The genomic proteins which are essential determinants of H. pylori-mediated pathogenesis and colonization are all, EXCEPT: \nSelect and explain. \nA. Hop proteins, B. Urease, C. Vacuolating cytotoxin (Vac A), D. Vacuolating cytotoxin (Vac B )', 'role': 'user'}, {'content': 'Answer: D \nExplanation: The genome of H. pylori encodes ~1500 proteins. Factors that are essential determinants of H. pylori-mediated pathogenesis and colonization are Outer membrane protein (Hop proteins) urease Vacuolating cytotoxin (Vac A). The majority of H. pylori strains contain a genomic fragment that encodes the cag pathogenicity island (cag-PAI). Several of the genes translocates Cag A into host cells. Once in the cell, Cag A activates a series of cellular events. Ref: Harrison-E-18,P-2442.', 'role': 'assistant'}]