This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nutrition, Subject name: Medicine
[{'content': 'Which of the vitamin deficiency lead to lactic acidosis \nSelect and explain. \nA. Riboflavin, B. Thiamine, C. Niacin, D. Pantothenic acid', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. B. ThiamineThiamine Deficiency Causes:a. Wet beriberii. Presents primarily with cardiovascular symptoms, due to impaired myocardial energy metabolism and dysautonomia, and can occur after 3 months of a thiamine-deficient diet.ii. Patients present with an enlarged heart, tachycardia,iii. High-output congestive heart failure, peripheral edema, and peripheral neuritis.b. Dry beriberii. Present with a symmetric peripheral neuropathy of the motor and sensory systems with diminished reflexes.ii. The neuropathy affects the legs most markedly, and patients have difficulty rising from a squatting position.c. Wernicke's encephalopathy/ consisting of horizontal nystagmus, ophthalmoplegia (due to weakness of one or more extraocular muscles), cerebellar ataxia, and mental impairment.d. Korsakoff psychosis. When there is an additional loss of memory and a confabulatory psychosis, the syndrome is known as Wernicke-Korsakoff syndrome.Prolonged Thiamin (Vitamin B1 ) deficiency, Leads to lactic acidosis", 'role': 'assistant'}]