This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pharmacology
[{'content': 'Sulfonylureas act by: \nSelect and explain. \nA. Decreasing glucagon secretion from pancreas, B. Decreasing insulin secretion from pancreas, C. Increasing gluconeogenesis, D. Increasing insulin secretion from pancreas', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans. (D) Increasing insulin secretion from pancreas(Ref: KDT 8/e p294)Sulfonylureas stimulate the release of insulin by the beta cells of the islets of Langerhans by blocking K+ channels. Glucagon secretion is also reduced by sulfonylureas, but it is a minor action.', 'role': 'assistant'}]