This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Microbiology
[{'content': 'Which of the following drug is effective against HIV with Y181C mutation? \nSelect and explain. \nA. Festinavir, B. Lersivirine, C. Elvitegravir, D. Dolutegravir', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Festinavir is an NI shown to be effective in adefovir and tenofovir resistanceLersivirine is an NNI effective against HIV with Y181C mutationElvitegravir is an integrase inhibitor used for initial / naive treatmentDolutegravir is an integrase inhibitor approved for raltegravir-resistant infections', 'role': 'assistant'}]