This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Orthopedics, Subject name: Surgery
[{'content': 'Not true about bone metastasis \nSelect and explain. \nA. Uncommon distal to elbow and knee., B. Breast secondary may be osteoblastic, C. Renal cell carcinoma secondary are expansile, D. Soft tissue sarcoma causes bony metastasis.', 'role': 'user'}, {'content': "Answer: D \nExplanation: Ans is 'd' ie soft tissue sarcomas causes bony metastasis Most common cause of osteoblastic metastasisIn males--- Prostate Cancer In Females-- Breast CancerSkeletal sites most frequently involvedSpine > proximal femur > pelvis > ribs > sternum > proximal humerus > skullLytic expansile metastasis seen inRenal Cancer Thyroid carcinomasOsteolytic lesions are associated with hypercalcemia and excretion of hydroxyproline - containing peptides.Osteoblastic lesions are associated with increased levels of serum alkaline phosphatase.Metastasis distal to knee and elbow is rare and usually arises from a primary tumors of theBronchus Colon or Bladder", 'role': 'assistant'}]