This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Medicine
[{'content': 'Decreased osmotic fragility is seen in - \nSelect and explain. \nA. Hereditary spherocytosis, B. Sickle cell ds, C. Autoimmune hemolytic anemia, D. Thalassemia', 'role': 'user'}, {'content': 'Answer: D \nExplanation: <p>In thalassemia,osmotic fragility characteristically reveals increased resistance to saline hemolysis that is decreased osmotic fragility.</p><p>Reference :Harsh mohan textbook of pathology sixth edition pg no 324.</p>', 'role': 'assistant'}]