This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Which of the following thiazide can be used in severe renal failure? \nSelect and explain. \nA. Chlorthiazide, B. Metolazone, C. Trichloromethazide, D. Bendroflumethiazide', 'role': 'user'}, {'content': "Answer: B \nExplanation: Thiazide diuretics can't be used in severe renal failure cases as they alter GFR. But Metolazone and Indapamide are the exceptions.", 'role': 'assistant'}]