This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Which finding on electron microscopy indicates irreversible cell injury- \nSelect and explain. \nA. Dilatation of endoplasmic reticulum, B. Dissociation of ribosomes from rough endoplasmic reticulum, C. Flocculent amorphous densities in the mitochondria, D. Myelin figures', 'role': 'user'}, {'content': "Answer: C \nExplanation: Ans. is 'c' i.e., Flocculent densities in mitochondria Mechanism of irreversible cell injury :? Membrane damage is the central factor in the pathogensis of irreversible cell injury. Note : o Earliest change of reversible cell injury is cellular swelling. o Myelin figures (laminated structure) derived from damaged membrane of organelles and plasma membrane, first appear during reversible injury, but become more pronounced in irreversible injury.", 'role': 'assistant'}]