This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: NEET Jan 2020, Subject name: Medicine
[{'content': 'Aquaporin deficiency cause? \nSelect and explain. \nA. Nephrogenic diabetes insipidus, B. Liddle syndrome, C. Baer syndrome, D. Gitelman syndrome', 'role': 'user'}, {'content': 'Answer: A \nExplanation: 1. Nephrogenic diabetes insipidus: Aquaporin 2" gene mutation impede the normal functionality of the kidney water channel, which results in the kidney being unable to absorb water. Autosomal recessivemanner. 2. Liddle syndrome: Gain of function of epithelial Na channel (ENaC) 3. Bater syndrome:- Defect in "Na-K-2Cl cotranspoer, Cl channel & ROMK" in loop of Henle. 4. Gitelman syndrome: Defect in "Na+-Cl- cotranspoer and TRPM6 transpoer" in DCT.', 'role': 'assistant'}]