This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Misc. (R.B.C), Subject name: Pathology
[{'content': 'Leptocyte in blood smears seen in? \nSelect and explain. \nA. Sickle cell anemia, B. Thalassemia, C. Post splenectomy, D. Uremia', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans. (b) Thalassemia(Ref: Robbins 9th/pg 649-652)Leptocytes are flattened red cells in which the volume-to- surface area ratio is decreased. Seen in iron deficiency anemia and thalassemia in which the red cells with a low mean cell hemoglobin (MCH) and mean cell volume (MCV) are unusually resistant to osmotic lysis.', 'role': 'assistant'}]