This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunology, Subject name: Microbiology
[{'content': 'IL-1 is produced by - \nSelect and explain. \nA. Macrophage, B. Helper T lymphocytes, C. B cells, D. Cytotoxic T-cells', 'role': 'user'}, {'content': 'Answer: A \nExplanation: It is principally secreted by macrophages and monocytes but can be produced by most other nucleated cells as well REF:Ananthanarayan & Panikers Textbook of Microbiology 9th Edition pg:154', 'role': 'assistant'}]