This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T., Subject name: Physiology
[{'content': 'Apical membrane of parietal cells contains which ion channels- \nSelect and explain. \nA. Na+ K+ ATPase, B. H+ K+ ATPase, C. Na+ K+ 2Cl- transporter, D. Na+ - Ca+2 cotransporter', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans. is \'b\' i.e., H+ K+ ATPase o The H~ are produced inside the parietal cell through the reaction of metabolic CO., with water. The reaction is catalyzed by carbonic anhydrase. H+ is secreted by proton pump (H~ K\'ATPase) into the gastric lumen in exchange with a K+ ion and the HCG, is transported out of the parietal cells at the basolateral membrane (by HCO3 - Cl- antiport ) into the interstitial fluid and from there into the blood. This HCO3- increases the blood pH. Hence after a meal, there is a rise in blood pH which is called the post-prandial alkaline tide.o The Cl" that enter the parietal cell in exchange for HCO3 are secreted into the lumen. So, inside the gastric lumen secreted H+ and Cl- from hydrochloric acid (HC1).', 'role': 'assistant'}]