This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General Concepts, Subject name: Pathology
[{'content': "A 52-year-old woman presents with a 1-year history of upper truncal obesity and moderate depression. Physical examination shows hirsutism and moon facies. A CT scan of the thorax displays a hilar mass. A transbronchial lung biopsy discloses small cell carcinoma. Electron microscopy of this patient's lung tumor will most likely reveal which of the following cytologic features? \nSelect and explain. \nA. Councilman bodies, B. Hyperplasia of endoplasmic reticulum, C. Mitochondrial calcification, D. Neuroendocrine granules", 'role': 'user'}, {'content': 'Answer: D \nExplanation: Neuroendocrine tumors may synthesize a number of hormones. The presence of small, membrane-bound granules with a dense core is a feature of these neoplasms. Dense granules are visible by electron microscopy. Carcinomas often exhibit desmosomes and specialized junctional complexes, which are structures that are not typical of sarcomas or lymphomas. Councilman bodies (choice A) are apoptotic hepatocytes (acidophilic bodies).', 'role': 'assistant'}]