This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'The ability of stem cells to cross the barrier of differentiation to transform into a cell of another lineage expressing the molecular characteristics of different cell type with the ability to perform the function of the new cell type is referred as: \nSelect and explain. \nA. De differentiation, B. Re differentiation, C. Trans differentiation, D. Sub differentiation', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Transdifferentiation is defined\xa0as:-\n\nThe change of a cell or tissue from one differentiated state to another.\nThe differentiation of a tissue-specific\xa0stem cell into another type of cell as for example a bone marrow stem cell\xa0differentiating into a neuron.\n\nDedifferentiation\n\nIt is a cellular process commonly believed to be uniquely available to lower life forms such as worms and\xa0amphibians in which a partially or terminally differentiated cell reverts to an earlier developmental stage.\nCells in cell culture can lose properties they originally had such as protein expression or change shape. This\xa0process is also termed dedifferentiation.\nDedifferentiation can also be observed in some tumour e.g. dedifferentiated liposarcomas which will show more\xa0immature areas in an otherwise differentiated liposarcoma.\nRegression of a specialized cell or tissue to a simpler, more embryonic, unspecialized form i.e. a reversal of cell\xa0development so that differentiation that had occurred previously is lost and the cells become more generalized in\xa0structure.\n\nRedifferentiation\n\nA process by which a group of once differentiated cells return to their original specialized form.', 'role': 'assistant'}]