This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti-Ulcer, Subject name: Pharmacology
[{'content': 'Proton pump inhibitors are most effective when they are given: \nSelect and explain. \nA. After meals, B. Shortly before meals, C. Along with H2 blockers, D. During prolonged fasting periods', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans. (B) Shortly before meals(Ref: KDT 8th/e p700)Proton pump inhibitors are used just before meals. Food stimulates the secretion of gastric acid that will be reduced by PPIs if these are given just before meals.', 'role': 'assistant'}]