This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Physiology & Histology, Subject name: Gynaecology & Obstetrics
[{'content': 'The Gene present in theca cell and absent in granulosa cell which enables theca cell to produce androgens: \nSelect and explain. \nA. CYP17 gene, B. CYP12 gene, C. p53, D. KRAS', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. is a, i.e. CYP 17 geneRef: Williams Gynae 3rd/ed, p350"Theca cells express all of the enzymes needed to produce androstenedione. Tins includes high levels of CYP17 gene expression, whose enzyme product catalyzes 17-hydroxylation. This is the rate limiting step in the conversion of progesterone to androgens."', 'role': 'assistant'}]