This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'TRUE about ahropathy in hemochromatosis: \nSelect and explain. \nA. It usually occurs after age 50, B. Lower limb joints are first affected, C. Acute brief attacks usually affects shoulder joints, D. Ahropathy improves with phlebotomy', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ahropathy develops in 25-50% of symptomatic hemochromatosis patients. MUST KNOW: It usually occurs after age of 50. The joints of the hands (the second and third metacarpophalangeal joint) are first affected. Acute brief attacks of synovitis may be associated with deposition of calcium pyrophosphate chondrocalcinosis or pseudogout), mainly in the knees. The ahropathy tends to progress despite removal of iron by phlebotomy. Ref: Harrison, Edition-18, Page-3164-5.', 'role': 'assistant'}]