This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Physiology
[{'content': 'Which of the following coagulation factors causes cross-linking and stabilization of clot? \nSelect and explain. \nA. Factor XIII, B. Thrombin, C. Factor VIII, D. Factor IX', 'role': 'user'}, {'content': 'Answer: A \nExplanation: The loose aggregation of platelets in the temporary plug is bound together and conveed into definitive clot bg fibrin. Fibrin is initially a loose mesh of interlacing strands. It is conveed by the formation of covalent cross-linkages to a dense tight aggregate. The latter reaction is catalyzed by activated factor 13 and requires calcium. Ref: Ganong&;s Review of medical physiology, 24th edition.Pg no. 566', 'role': 'assistant'}]