This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Which of the following drug is an inverse agonist at H3 receptors used for Narcolepsy? \nSelect and explain. \nA. Dexmedetomidine, B. Pitolisant, C. Icatibont, D. Secukinumab', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Pitolisant (Tiprolisant) is a inverse agonist of H3\xa0receptors approved for Narcolepsy.\xa0H3\xa0receptors are presynaptic receptors and inverse agonist will lead to increased histamine release and promote wakefulness.', 'role': 'assistant'}]