This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Lukemia, Subject name: Pathology
[{'content': 'The cause of the severe hemorrhage in Acute Promyelocytic Leukemia is? \nSelect and explain. \nA. Disseminated intravascular coagulation, B. Immune complex deposits on blood vessels, C. Thrombocytopenia, D. Thrombocytosis', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans- (a) Disseminated Intravascular coagulationRef: Robbin's pathology 9th ed. /317-18, 612, 663* Acute promyelocytic leukemia (APL) is characterized by more severe hemorrhagic phenomena than those of other acute leukemias.* The hemorrhagic diathesis results from disseminated intravascular coagulation.* About 40 percent of patients with APL have a chromosomal abnormality with translocation from the long arm of 17 to 15 (t 15q;17q)* The patient may present with massive ecchymoses, hematuria, epistaxis, or meno-metrorrhagia.", 'role': 'assistant'}]