This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetic and genetic disorders, Subject name: Pediatrics
[{'content': 'Wiskott-Aldrich syndrome is characterized by all of the following except: \nSelect and explain. \nA. X-linked recessive mode of inheritance, B. Atopic dermatitis and eczema during infancy, C. Thrombocytopenia, D. IgM is increased', 'role': 'user'}, {'content': 'Answer: D \nExplanation: IgM is decreased in Wiskott-Aldrich syndrome, not increased . Wiskott-Aldrich syndrome characterized by X-linked recessive Thrombocytopenia Infections Eczema It is associated with decreased IgM, increased IgA, and increased IgE levels . Ref: Nelson textbook of pediatrics 21st edition Pgno: 1117', 'role': 'assistant'}]