This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Intravenous Anesthetic Agents, Subject name: Anaesthesia
[{'content': 'Which intravenous anesthetic agent has local anaesthetic the propeies- \nSelect and explain. \nA. Ketamine, B. Propofol, C. Thiopentone, D. Etomidate', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ketamine interact with voltage - gated sodium channels sharing binding site with local anesthetic. Local Anesthetics can also bind to other receptors like voltage -gated potassium channels and nicotinic acetylcholine receptors, it is widely accepted that anesthesia and analgesia is by interaction with Na+ channel. Other drugs - ketamine, Tricyclic antidepressant and Anticonvulsant has also effect on Na+ channel.', 'role': 'assistant'}]