This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Osteomyelitis, Subject name: Orthopaedics
[{'content': 'Osteomyelitis in sickle cell anemia is due to. \nSelect and explain. \nA. Salmonella, B. Streptococcus, C. Haemophilus, D. Neisseria', 'role': 'user'}, {'content': 'Answer: A \nExplanation: (A)- Musculoskeletal abnormalities in Sickle cell disease.1. Dactylitis or hand-foot syndrome is swelling, tenderness and warmth of hands and feet (<5 years age group).2. Sterile joint effusion and periarticular pain in sickle cell crisis (knee and elbow are usually involved).3. Diaphyseal osteomyelitis of long tubular bone esp. Salmonella infections, also it can involve multiple bones.4. Infarction of bone marrow and avascular necrosis.', 'role': 'assistant'}]