This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Pathology
[{'content': 'BCR ABL gene mutation is seen in? \nSelect and explain. \nA. CML, B. AML, C. CLL, D. ALL', 'role': 'user'}, {'content': 'Answer: A \nExplanation: CML is distinguished from other myeloproliferative disorders by the presence of a chimeric BCR-ABL gene derived from the poions of BCR gene on chromosome 22 and ABL gene on chromosome 9.It directs the synthesis of a constitutively active BCR-ABL tyrosine kinase. Reference; Robbins and Cotran Pathologic basis of disease.South Asia Edition volume 1.page no. 616', 'role': 'assistant'}]