This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
[{'content': 'Immunoglobulin variation does not depend on - \nSelect and explain. \nA. Light chain, B. Heavy chain, C. Amino acid sequence, D. Constant region', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Light chain The isotype variation or class of antibody is due to variation in the amino acid sequence in the constant region of the heavy chain.Because there are five potential variation in the aminoacid sequence in the constant region there are five classes of antibody i.e. IgG, IgM, IgA, IgD, IgE.", 'role': 'assistant'}]