This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.V.S, Subject name: Medicine
[{'content': 'In severe aoic stenosis true finding is \nSelect and explain. \nA. Late systolic ejection click, B. Heaving with outward apex, C. ST segment changes in ECG, D. Loud S2', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ref Harrison 19 th ed pg 1531 most patients with severe AS, there is LV hyperophy. In advanced cases, ST-segment depression and T-wave inversion (LV "strain") in standard leads I and aVL and in the left precordial leads are evident. However, there is no close correlation between the ECG and the hemodynamic severity of obstruction, and the absence of ECG signs of LV hyperophy does not exclude severe obstruction.', 'role': 'assistant'}]