This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Central Nervous system, Subject name: Pharmacology
[{'content': 'Which of the following statement is not true about domperidone? \nSelect and explain. \nA. It rarely causes extrapyramidal side effects, B. It is a D2 receptor antagonist, C. Its antiemetic efficacy is higher than metoclopramide, D. It causes loose stool', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Domperidone is an antiemetic which is classed under prokinetic drugs. It is a D2 antagonist; But it crosses blood brain barrier poorly - hence extrapyramidal side effects are rare, hyperprolactinemia can occur. Its antiemetic efficacy is LOWER than metoclopramide. Side effects are much less than with metoclopramide; dry mouth, loose stools, headache, rashes, galactorrhea, cardiac arrhythmias on rapid IV injection.Ref:KD Tripathi 8th ed.', 'role': 'assistant'}]