This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hepatitis, Subject name: Medicine
[{'content': "HbsAg carrier state is not associated with: \nSelect and explain. \nA. Down's syndrome, B. Chronic renal failure, C. Poly-aeritis nodosa (PAN), D. Infectious mononucleosis", 'role': 'user'}, {'content': "Answer: D \nExplanation: Glomerulonephritis with the nephrotic syndrome is observed occasionally; HBsAg, Ig and C3 deposition has been found in the glomerular basement membrane. Polyaeritis Nodosa develops in fewer than 1% of patients with chronic HBV infection, 20-30% of patients with PAN have HBsAg in serum. Due to decreased humoral response and repeated admissions in hospital in childhood patients of Down's have a higher prevalence of hepatitis B infection.", 'role': 'assistant'}]