This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': "Libman Sach's endocarditis is associated with? \nSelect and explain. \nA. Rheumatic heart disease, B. SLE, C. Carcinoma, D. None", 'role': 'user'}, {'content': 'Answer: B \nExplanation: Libman-Sacks endocarditis refers to sterile vegetations that can develop on the valves of\xa0patients with systemic lupus erythematosus. Libman-Sacks Endocarditis\nThese lesions presumably occur because of immune complex deposition and thus have also\xa0inflammation. With increasing use of steroids for Rx of lupus, Libman-Sacks endocarditis has become uncommon.\nMorphology-Histology:\n\n- Small (1-4 mm in diameter) sterile, granular pink vegetations;\n- No special predilection for the lines of valve closure.\n- Can be located on the undersurfaces of the atrioventricular valves, on the cords, or even on the\xa0atrial or ventricular endocardium.\n- The lesions are finely granular, fibrinous eosinophilic vegetations containing nuclear debris. An\xa0intense valvulitis is often present, with fibrinoid necrosis of the valve substance adjacent to the\xa0vegetation. Subsequent fibrosis and serious deformity can result in that resemble chronic RHD.', 'role': 'assistant'}]