This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Disorders of the Respiratory Tract, Subject name: Pediatrics
[{'content': 'Omalizumab True statement is- \nSelect and explain. \nA. Anti-IgE, B. Used as add on therapy in moderate to severe asthma prophylaxis, C. Givn subcutaneously, D. All o above', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans. is \'d\' i.e.* All of above Anti-IgE (Omalizumab).o Omalizumab is a humanized monoclonal antibody that binds IgE, thereby presenting its binding to the high- affinity IgE receptor and blocking IgE-mediated allergic responses and inflammation,o approved for patients >12 yr old with moderate to severe asthma,o It is given even\' 2-4 wk subcutaneously based on body weight and serum IgE levels.o Its clinical efficacy-> as an "add-on " therapy for patients with moderate to severe allergic asthma It is generally well tolerated, although local injection site reactions can occur.', 'role': 'assistant'}]