This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'If cellular proteins do not fold into a specific conformation, their functions are affected. Ceain disorders arise, if specific proteins are misfolded. Which of the following disorders arises due to conformational isomerization? \nSelect and explain. \nA. Familial fatal insomnia, B. Hepatitis delta, C. Pernicious anemia, D. Lesch-Nyhan syndrome', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Familial fatal insomnia', 'role': 'assistant'}]