This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy, Subject name: Pharmacology
[{'content': 'All are true about cefuroxime Except: \nSelect and explain. \nA. Inhibit cell was synthesis, B. Third generation cephalosporin, C. Some acquired resistance with penicillin, D. More active against gram negative organisms', 'role': 'user'}, {'content': 'Answer: B \nExplanation: It is a 2 nd generation cephalosporin,resistant to gram-negative lactamases: has high activity against organisms producing these enzymes including PPNG and ampicillin-resistant H. influenzae, while retaining significant activity on gram-positive cocci and ceain anaerobes. It is well tolerated by i.m. route and attains relatively higher CSF levels, but has been superseded by 3rd generation cephalosporins in the treatment of meningitis. ESSENTIALS OF MEDICAL PHARMACOLOGY page no.727', 'role': 'assistant'}]