This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Small intestine, Subject name: Surgery
[{'content': "A 25-years old male patient presents with pigmentation of the lips and oral mucosa and intestinal polyps. His sister also gives the same history. Most probable diagnosis is: \nSelect and explain. \nA. Carcinoid tumor, B. Melanoma, C. Villous adenoma, D. Peutz-Jegher's syndrome", 'role': 'user'}, {'content': "Answer: D \nExplanation: Peutz-Jegher's syndrome - Multiple hamaomatous polyps in S.I - M/C pa - Jejunum- Gene- LDB-1 / STK-11 - 19p- Hyper melanotic macules over Lips &Buccal mucosa - Does not |risk of colorectal cancer- | risk of S.I. malignancy- | risk of- Breast - Thyroid- Pancreas (max risk)- Endometrial - Seoli cell tumor of testis", 'role': 'assistant'}]