This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.N.S, Subject name: Pharmacology
[{'content': 'Vigabatrin acts by: \nSelect and explain. \nA. GABA receptor inhibitor, B. Glutamate receptor inhibitor, C. GABA transaminase inhibitor, D. GABA transport inhibitor', 'role': 'user'}, {'content': 'Answer: C \nExplanation: (Ref: Katzung, 14th ed. pg. 431-32)* VIGABATRIN is GABAergic drug acts by inhibiting enzyme GABA transaminase.* This enzyme inhibition causes increased level of GABA in the neuron.* Use:# DOC in infantile spasm + Tuberous sclerosis# Simple and complex partial seizure* Contraindicated in absence seizure, Myoclonic seizure, Pre-existing visual field defect.* Side effect: Visual field defect due to peripheral retinal atrophy, weight gain, amnesia* GABA uptake transport inhibitor: TIAGABINE', 'role': 'assistant'}]