This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Congenital CNS malformations, Subject name: Pediatrics
[{'content': 'Agenesis of corpus callosum with retinal colobomas and intellectual disability is seen in: \nSelect and explain. \nA. Alagille syndrome, B. Aicardi syndrome, C. Ape syndrome, D. Ataxia telangiectasia', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Aicardi syndrome: - Characterized by Agenesis of corpus callosum Retinal colobomas Infantile spasms in girls Intellectual disability Alagille Syndrome- Triangular faces, conjugated jaundice Ape syndrome is a genetic disorder characterized by skeletal abnormalities. A key feature ofApe syndrome is the premature closure of the bones of the skull. Ataxia telangiectasia is a rare childhood disease. It affects the brain and other pas of the body. Ataxia refers to uncoordinated movements during walking. Telangiectasias are enlarged blood vessels (capillaries) just below the surface of the skin.', 'role': 'assistant'}]