This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: AML & ALL, Subject name: Medicine
[{'content': 'Most common subtype of adult ALL? \nSelect and explain. \nA. B- lineage ALL, B. Pre-B- ALL, C. T-lineage ALL, D. Coical T-ALL', 'role': 'user'}, {'content': 'Answer: A \nExplanation: ALL is the most frequent neoplastic disease in children with an early peak at the age of 3-4 years More than 70% of adult ALLs are of B-cell origin, and the most frequent immunological subtype, common ALL, is characterized by the presence of ALL antigen, a glycoprotein (gp100/CD10). Pro-B-ALL (also termedearly B-precursor ALL) is a leukemia that was formerly termednon-T,non-B-ALL, ornull-ALL as neither T-cell nor B-cell features could be demonstrated. This subtype forms about 11% of adult ALL. Approximately 25% of adult ALL belongs to the T-cell lineage. All cases express the T-cell antigen (gp40, CD7) and cytoplasmatic or surface CD3. They may, according to their step of T-cell differentiation, express other T-cell antigens, e.g., the E-rosette receptor (CD2) and/or the coical thymocyte antigen T6 (CD1). A minority of T-ALL blast cells may also express common ALL antigen together with other T-cell antigens. According to these markers, it is possible to distinguish a pro-T-ALL (also termedearly T-precursor ALL), coical, or thymic T-ALL and a mature T-ALL expressing different stages of differentiation.', 'role': 'assistant'}]