This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Type 1 Dentinogenesis imperfecta is caused by mutation in: \nSelect and explain. \nA. DMP-1 gene, B. BSP- 1 gene, C. DSPP gene, D. SPP1 gene', 'role': 'user'}, {'content': "Answer: C \nExplanation: Type 1 Dentinogenesis imperfecta is caused by a mutation in the DSPP gene (gene map locus 4q21.3), encoding dentin phosphoprotein and dentin sialoprotein.\xa0While Type 2 is caused by DMP-1, BSP-1, SPP1 gene.\nRef: Shafer's textbook of oral pathology 7th edition page55", 'role': 'assistant'}]