This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Medicine
[{'content': 'True about Light microscopic changes in Minimal Change Glomerulonephritis is - \nSelect and explain. \nA. No Abnormality, B. Fusion of foot process, C. Absence of Immunoglobulins, D. Absence of complement', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Minimal change nephropathy Minimal change disease occurs at all ages but accounts for most cases of nephrotic syndrome in children and about one-quaer of adult cases. It is caused by reversible dysfunction of podocytes. On light microscopy, the glomeruli appear normal , but fusion of podocyte foot processes is observed on electron microscopy. The presentation is with nephrotic syndrome, which typically is severe; Ref Harrison20th edition pg 278', 'role': 'assistant'}]