This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General anaesthesia, Subject name: Anaesthesia
[{'content': 'Which of the following drug is contraindicated in a patient with raised intracranial pressure? \nSelect and explain. \nA. Thiopentone, B. Propofol, C. Midazolam, D. Ketamine', 'role': 'user'}, {'content': "Answer: D \nExplanation: ketamine increases all the pressures - blood pressure intracranial pressure intragastric pressure intraocular pressure In patients with increased ICP who are breathing spontaneously, ketamine should be used with caution because it can increase ICP and has been repoed to cause apnea. It is contraindicated. Ref: Miller's anesthesia 8th edition.", 'role': 'assistant'}]