This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Neuromuscular Blocker, Subject name: Anaesthesia
[{'content': 'Which by product of vecuronium is associated with peripheral neuropathy on prolonged infusion- \nSelect and explain. \nA. 3- hydroxy vecuronium, B. 17-hydroxy vecuronium, C. 3, 17 (OH2) metabolite, D. All', 'role': 'user'}, {'content': 'Answer: A \nExplanation: The most potent byproduct of vecuronium is 3-hydroxy vecuronium, with approximately 60% of the activity of vecuronium, is excreted by the kidney and may be responsible for prolonged paralysis. Vecuronium - 1. It is unstable in solution and, for this reason, is supplied as a lyophilized powder that must be dissolved in sterile water before its use. 2. Both hepatic and renal metabolism. 3. To be used cautiously in pretesting liver & renal dysfunction 4. Neonate, obstetric, geriatric and obese prolonged duration of action is observed.', 'role': 'assistant'}]