This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Psoriasis, Subject name: Dental
[{'content': 'Which of the following anti TNF-a agents binds to both soluble and transmembrane bound forms of TNF-a? \nSelect and explain. \nA. Etanercept, B. Infliximab, C. Adalimumab, D. Onercept', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Anti-TNF-ALPHA blockers Initially developed for therapy of rheumatoid ahritis are in advanced trials for psoriasis. 2 main agents are Infliximab-Chimeric human-murine IgG antibody to TNF-ALPHA; Etanercept- Dimeric fusion protein consisting of the extracellular poion of the human p75 TNF-ALPHA receptor linked to the Fc poion of human IgG1.', 'role': 'assistant'}]