This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General physiology, Subject name: Physiology
[{'content': 'Which of the following organelles plays a pivotal role in apoptosis? \nSelect and explain. \nA. Mitochondria, B. Endoplasmic reticulum, C. Nucleus, D. Golgi apparatus', 'role': 'user'}, {'content': 'Answer: A \nExplanation: The Mitochondrial (Intrinsic) Pathway of Apoptosis Mitochondria contain several proteins that are capable of inducing apoptosis; these proteins include cytochrome c and other proteins that neutralize endogenous inhibitors of apoptosis. The choice between cell survival and death is determined by the permeability of mitochondria, which is controlled by a family of more than 20 proteins, the prototype of which is Bcl-2.(Reference: Robbins Basic Pathology, 9th edition Page no: 19)', 'role': 'assistant'}]