This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': "Which of the following is not a channelopathy? \nSelect and explain. \nA. Cystic fibrosis, B. Liddle's syndrome, C. Tay-sach's disease, D. Hypokalemic periodic paralysis", 'role': 'user'}, {'content': 'Answer: C \nExplanation: Channelopathy\n\nA channelopathy refers to a disease involving dysfunction of an ion channel.\nChannelopathies are known that involve the ion channels for potassium, chloride, sodium and calcium\nIon channels serve many functions apart from electrical signal transduction: chemical signalling ( Ca 2+ as a second messenger), transepithelial transport, regulation of cytoplasmic or vesicular ion concentration and pH, and regulation of cell volume. Therefore, ion channel dysfunction can cause diseases in many tissues.', 'role': 'assistant'}]