This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Pathology
[{'content': 'The effect of chilling in refrigeration analgesia includes \nSelect and explain. \nA. Interference with conduction of nerve impulse, B. Reduction of metabolic rate and oxygen requirement, C. Inhibition of bacterial growth and infection, D. All of the above', 'role': 'user'}, {'content': 'Answer: D \nExplanation: For chilling analgesia (cryoanalgesia) CO2 or N2O is used. At such low temperatures there is inhibition of nerve conduction producing analgesia. Hypothermia decreases metabolic rate and oxygen consumption of tissue. Hypothermia inhibits the bacterial growth. Healing is also retarded at low temperatures.', 'role': 'assistant'}]