This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'Treatment of choice of stage III CIN in 40-year-old female is: \nSelect and explain. \nA. Hysterectomy, B. Laser coagulation, C. Cryocoagulation, D. Cone excision', 'role': 'user'}, {'content': 'Answer: A \nExplanation: As discussed in preceding text - management options in CIN are\n\nAblative techniques like cryosurgery, laser vaporization therapy\nExcisional methods - like LEEP (Loop electro excisional procedure) or LLETZ\n\t(large loop excision of transformation zone), condition surgery\nHysterectomy\n\nIn general, the major drawback of ablative procedures is - it destroys the tissue and so no tissue specimen is available for additional histologic evaluation during follow-up.\nCryotherapy: \n\nIt should be considered only if. There is a minor degree of CIN localized and it is\n\n"This method is ideal for minor degrees and localized CIN" \xa0- Dutta 6th /ed p 327\n\nThus in this patient - cryotherapy will not be done as she has CIN III\n\nLaser ablation: \n\nRarely used in practice. Used only if CIN extends to vaginal fornices.\n\nRemember\n\nMost early CIN is now managed expectantly so the need for ablation is decreasing."\n\nHysterectomy: \n\nAs far as hysterectomy is concerned - it is taken as too radical a procedure for management of CIN and is reserved for special circumstances like recurring CIN -\nRecent management says whether the patient is young or old -CIN111 should be managed by LEEP/LLETZ.', 'role': 'assistant'}]