This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'Which of the follow ing is not a rate-limiting enzyme- \nSelect and explain. \nA. HMG CoA reductase, B. Phosphofructokinase, C. Acetyl CoA carboxylase, D. Malonate dehydrogenase', 'role': 'user'}, {'content': "Answer: D \nExplanation: Ans. is 'd' i.e., Malonate dehydrogenase o Malonate dehydrogenase is not a rate-limiting enzymes. o HMG-CoA reductase (in cholesterol synthesis), phosphofructokinase I (in glycolysis) and acetyl-CoA carboxylase (in fatty acid synthesis) are rate-limiting enzymes, Reactions Rate-limiting enzymes Glycolysis Phosphofructokinase Glycogen synthesis Glycogen synthetase Glycogenolysis Glycogen phosphorylase TCA cycle Isocitrate dehydrogenase Fatty- acid synthesis Acetyl CoA carboxylase Cholesterol synthesis HMG CoA reductase Ketone body synthesis HMG CoA synthase Bile acid synthesis 7-oc-hydroxylase Catecholamine synthesis Tyrosine hydroxylase Urea synthesis CPS - I", 'role': 'assistant'}]