This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Mendalian Inheritance, Subject name: Biochemistry
[{'content': 'If both parents have sickle cell anemia, then the likelihood of children (offsprings) having the disease is- \nSelect and explain. \nA. 10%, B. 25%, C. 50%, D. 100%', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Sickle cell anemia Inherited as AR. If both parents are affected, means both parents are homozygous for trait as recessive allele is expressed in only homozygous state. Then 100 % offsprings will inherit the disease. If Both parents are carriers then only 25% will be affected', 'role': 'assistant'}]