This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Apoptosis, Subject name: Pathology
[{'content': 'Not true about apoptosis - \nSelect and explain. \nA. Increase in lysosomal enzyme, B. Increase in caspases, C. Phosphatidyl serine has important role, D. Intemucleosomal cleavage of nucleus', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Increase in lysosomal enzymeApoptosiso Caspases are central to the pathogenesis of apoptosis.# The lysis in apoptosis is caused due to action of caspase.o Mitochondrias are the most important organelles involved in initiation and regulation of apoptosis.# Hallmark of apoptosis is permeability of the mitochondrial membrane.o formally phosphatidyl serine is located on the inner cytosolic surface of plasma membrane# In apoptotic cell this phosphatidyl serine is translocated to the outer (extracellular) surface of plasma membrane.o Lysosome and other organelles remain intact.", 'role': 'assistant'}]