This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'Histology from a bone biopsy from proximal femur is given below of a 50 year old with bone pain.  What is your diagnosis? \nSelect and explain. \nA. Osteomalacia, B. Paget’s disease, C. Osteoporosis, D. Osteosclerosis', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ref. Robbins Pathology. 9th edition. Page. 1191\n\xa0\nPaget Disease\n\nDiagnostic features are increased osteoclastic and osteoblastic activity with supportive radiologic findings\nAcute: primarily woven bone; focal mosaic pattern of lamellar bone, resembles jigsaw puzzle with prominent irregular cement lines; osteoclasts present at surface of bone but don’t tunnel; in osteolytic phase, osteoclasts may have up to 100 nuclei\nChronic: thick trabeculae and thicker bones; fine fibrosis of marrow (Osteosclerotic stage)\nThe picture is also known as mosaic pattern of bone', 'role': 'assistant'}]