This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunology and Rheumatology, Subject name: Medicine
[{'content': 'Which is the best treatment in a case of PNH presenting with black colour urine? \nSelect and explain. \nA. Eculizumab, B. Rituximab, C. Infliximab, D. Prednisolone', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans. D. PrednisoloneTreatment:Best Initial treatment to control Hemolysis = PrednisoloneBest treatment = BMTBest treatment to prevent chronic hemolysis or clot formation = Eculizumab:Eculizumab is a monoclonal antibody that specifically binds to the complement protein C5, thus inhibiting terminal complement mediated intravascular hemolysis in PNH patients.', 'role': 'assistant'}]