This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'In thromboasthenia there is a defect in - \nSelect and explain. \nA. Platelet aggregation, B. Platelet adhesion, C. Decreased ADP release, D. Disordered platelet secretion', 'role': 'user'}, {'content': "Answer: A \nExplanation: Platelet adhesion\n\nPlatelet adhesion refers to the binding of platelets to subendothelial matrix.\nPlatelet membrane glycoprotein\xa0Ib - IX\xa0is essential for platelet adhesion to subendothelial matrix.\n\nPlatelet aggregation\n\nPlatelet aggregation refers to adherence of platelets to one another.\nPlatelet membrane glycoprotein\xa0IIb - IIIa\xa0helps in aggregation.\n\nCongenital dysfunction of platelet\n1. \xa0Bernard-Soulier syndrome\n\nDefect in platelet\xa0adhesion\xa0due to inherited deficiency of glycoprotein\xa0Ib - IX.\n\n2. Glanzmann's thrombasthenia\n\nDefect in platelet aggregation due to inherited deficiency of glycoprotein IIb - IIIa.", 'role': 'assistant'}]