This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'All of the following are true about temporal arteritis except - \nSelect and explain. \nA. Polymyalgia rheumatica, B. Anemia, C. Low ESR, D. Sudden blindness', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Giant cell arteritis or team oral arteritis\n\nIt is the most common form of systemic vasculitis in adults.\nIt is an acute and chronic, often granulomatous inflammation of arteries of large to small size.\nGiant cell arteritis affects principally the arteries in the head, especially the temporal arteries which is the extracranial branch of the carotid artery.\nVertebral and ophthalmic arteries may also be involved.\nA segment of the affected artery develops nodular thickening with narrowing of the lumen.\nThere is granulomatous inflammation in the vessel wall with a foreign body and Langhans type multinucleated giant cells and fragmentation of internal elastic lamina.\n\nPresentation of Giant cell arteritis \n\nConstitutional symptoms\nMost common nonspecific symptoms\nInclude malaise, fatigue, anorexia and weight loss.\nThese symptoms are due to the generalized involvement of the body and are not related to any organ involvement.\n\nA headache\n\nIt is the most common vasculitis related symptom.\nMost commonly over temporal region.\nJaw claudication\nIt is the most specific symptom of GCA.\nIt is manifested as pain in masseter when eating food that requires vigorous chewing because oxygen demand of the masseter exceeds the supply provided by narrowed and inflamed arteries.\n\nVisual symptoms\n\nDiplopia and visual loss.\nOphthalmic artery involvement can lead to sudden blindness which is the most feared complication of GCA.\n\nPolymyalgia rheumatic\n\nAching and stiffness of the shoulder, neck and lip girdle area.\n\nArthritis\nRaised ESR\n\nNormocytic-Normochromic anemia', 'role': 'assistant'}]