This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'R-RNA is mainly produced in - \nSelect and explain. \nA. Nucleus, B. Nucleolus, C. Ribosome, D. Endoplasmic reticulum', 'role': 'user'}, {'content': "Answer: B \nExplanation: B i.e., NucleolusThe sigma (a) subunit (factor) enables RNA polymerase to recognize promoter regions on DNAQ.Like DNA polymerase, RNA polymerase uses nucleoside triphosphate as substrates & releases pyrophosphate each time a nucleoside monophosphate is added to growing chain. And as with replcation, transcription is always in 5' -s 3'direction. However, incontrast to DNA polymerase, RNA polymerase (both in eukaryotes and prokaryotes) does not require primer and has no known proofreading activityQ.", 'role': 'assistant'}]