This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Virology, Subject name: Medicine
[{'content': 'HIV infects most commonly \nSelect and explain. \nA. CD4+helper cells, B. CD8+cells, C. Macrophage, D. Neutrophil', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e CD4+ helper cells CD4+ T lymphocytes and CD4+ cells of monocyte lineage are the principal targets of HIV.Virtually any cell that expresses the CD4+molecule together with Coreceptor molecules can potentially be infected with H.I.V. e.g.Dendritic cellsLangerhans cellsEven Megakaryocytes, eosinophilis, Astrocytes, oligodendrocytes, microglial cells, CD4+ T cells can also be infected with HIV.", 'role': 'assistant'}]