This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Degeneration of the basement membrane is mediated by: \nSelect and explain. \nA. Oxidases, B. Elastases, C. Hydroxylases, D. Metallo proteinase', 'role': 'user'}, {'content': "Answer: D \nExplanation: Matrix Metalloproteins MMP9 and MMP2 are collagenases that cleave type IV collagen of epithelial and vascular basement membranes'. Ref: Matrix Metalloproteinases By Robe P. Mecham, William C. Parks, Page 2; Robbin's Illustrated Pathology, 7th Edition, Pages 103, 110, 111, 312", 'role': 'assistant'}]