This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: TB of the Spine, Subject name: Orthopaedics
[{'content': 'The 1st sign of TB is: \nSelect and explain. \nA. Narrowing of intervertebral space, B. Rarefaction of vertebral bodies, C. Destruction of laminae, D. Fusion of spinous processes', 'role': 'user'}, {'content': 'Answer: A \nExplanation: (a)- The earliest feature is loss of curvature due to paravertebral spasm.- The next radiological feature of spinal tuberculosis is reduction of intervertebral disk space and osteoporosis of two adjacent vertebrae sometimes with fuzziness of the endplates.', 'role': 'assistant'}]