This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Which of the following pathway is seen in basal cell carcinoma \nSelect and explain. \nA. mTOR, B. Sonic Hedgehog, C. WNT, D. RAS', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Answer- B. Sonic HedgehogBasal cell carcinomaLocally aggressive tumorAssociated with mutations which activate Hedgehog pathway signalling.Gorlin syndrome is associated with gene PTCH, a tumor suppressor genePTCh is receptor for Sonic hedgehog, which determines polarity during embryonic development.Basal cell carcinoma presents as pearly papules.', 'role': 'assistant'}]