This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: miscellaneous, Subject name: Biochemistry
[{'content': 'Glycated haemoglobin reflects blood glucose of preceding \nSelect and explain. \nA. 0-1 week, B. 2-3 week, C. 4-5 week, D. 6-8 week', 'role': 'user'}, {'content': 'Answer: D \nExplanation: When blood glucose enters the erythrocytes, it glycates the e-amino group of lysyl residues and the amino terminals of haemoglobin.The fraction of haemoglobin glycated, normally about 5%, is propoionate to blood glucose concentration.Since the half-life of an erythrocyte is typically 60 days, the level of glycated haemoglobin (HbA1c) reflects the mean blood glucose concentration over the preceding 6 to 8 weeks. Measurement of HbA1c, therefore, provides valuable information for management of diabetes mellitus.Reference: Harper biochemistry, 30th edition, page no 58', 'role': 'assistant'}]