This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': "Hegar's sign of pregnancy is : \nSelect and explain. \nA. Uterine contraction, B. Bluish discoloration of vagina, C. Softening of isthmus, D. Quickening", 'role': 'user'}, {'content': "Answer: C \nExplanation: Ans. is c i.e. Softening of isthmus Hegar's siy:1 is present ,n 2/3rd cases and is demonstrated between 6 - 10 weeks. The sign is based on the fact that - upper pa of the body is enlarged by the growing ovum whereas lower pa of the body of the uterus i.e. isthmus is empty and soft and cervix is comparatively firm. Because of theses variations in consistency- on bimanual examination, the abdominal and vaginal fingers seem to appose below body of the uterus.", 'role': 'assistant'}]