This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: vitamins, Subject name: Biochemistry
[{'content': 'Conversion of Pyruvate to Acetyl CoA does not require \nSelect and explain. \nA. Thiamine, B. TPP, C. Pyridoxine, D. FAD', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Pyruvate is conveed to acetyl CoA by oxidative decarboxylation catalysed by a multienzyme complex, known as pyruvate dehydrogenase complex (PDH) The enzyme PDH requires five cofactors (coenzymes), namely--TPP(thiamine pyrophosphate), lipoamide, FAD, coenzyme A and NAD+ ref Satyanarayana biochemistry 4th ed page 252', 'role': 'assistant'}]