This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Anti androgen used in hea failure ? \nSelect and explain. \nA. Carvedilol, B. Sampatrilat, C. Spironolactone, D. Abiraterone', 'role': 'user'}, {'content': "Answer: C \nExplanation: Ans. is 'c' i.e., Spironolactone o Spironolactone and eplerenone are the aldosterone antagonists. They are used as potassium sparing diuretics. Their diurectic effect is quite feeble, but in CHF these drugs reduce the moality (at doses lower than diuretic doses) by antagonizing the effect of aldosterone (reversal of remodelling). Spironolactone also possesses anti- androgenic effects.", 'role': 'assistant'}]