This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: NEET 2019, Subject name: Anaesthesia
[{'content': 'Cis atracurium is better then atracurium because:- \nSelect and explain. \nA. Less histamine release, B. Less half life, C. Low drug dose, D. Low cost', 'role': 'user'}, {'content': "Answer: A \nExplanation: Atracurium Cis-atracurium Mixture of cis-isomers Pure cis-isomer Histamine release No / minimal release CVS unstable CVS stable Less potent Dose - 0.5-0.6mh/kg More potent Dose - 0.1-0.2 mg/kg - Cis-atracurium and atracurium are dependent on Hoffman elimination - Cis-atracurium's duration of action is more predictable because of spontaneous breakdown. Although atracurium undergoes similar elimination, it is less potent than cis-atracurium, so its breakdown product, laudanosine, is found in higher concentrations", 'role': 'assistant'}]