This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Glucose can be synthesized from all of the following except ? \nSelect and explain. \nA. Acetoacetate, B. Lactic Acid, C. Glycerol, D. Amino acid', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Acetoacetate is a ketone body.During ketolysis,it is activated to acetoacetyl CoA which gives acetyl CoA.Acetyl CoA can not be reconveed back to pyruvate so acetoacetate can not be utilized for gluconeogenesis. Ref: Janson L.W., Tischler M.E. (2012). Chapter 2. Carbohydrates. In L.W. Janson, M.E. Tischler (Eds), The Big Picture: Medical Biochemistry.', 'role': 'assistant'}]