This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti Microbial, Subject name: Pharmacology
[{'content': 'Which of the following aminoglycoside is cochleotoxic: \nSelect and explain. \nA. Kanamycin, B. Streptomycin, C. Gentamycin, D. Minocycline', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ref: Goodman & Gillman 13th ed. P 1044-45* All aminoglycosides have the potential to produce reversible and irreversible vestibular, cochlear, renal toxicity and neuromuscular blockade.* Aminoglycoside-induced ototoxicity may result in irreversible, bilateral, high-frequency hearing loss or vestibular hypofunction.* A high-pitched tinnitus often is the first symptom of cochlear toxicity.* Drugs like amikacin, neomycin and kanamycin are specifically cochleotoxic > vestibulotoxic.* Gentamicin, streptomycin is vestiblar > cochleotoxic* Tobramycin: Cochlear = Vestibular toxicity both.', 'role': 'assistant'}]