This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Biochemistry
[{'content': 'Multiple sclerosis is characterized by a loss of which lipids \nSelect and explain. \nA. Phospholipids and ceramide, B. Sphingolipids and ceramide, C. Sphingolipids and gangliosides, D. Phospholipids and sphingolipids', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Phospholipids and sphingolipids Ceramide is an impoant signaling molecule for apoptosis and is a precursor for glycosphingolipids and gangliosides. Sphingolipids and phospholipids are structural lipids in membranes. Multiple sclerosis is a demyelinating disease in which both phospholipid and sphingolipid levels are decreased, unlike lipid storage diseases, which affect sphingolipid levels. Ref : www.ncbi.nlm.gov', 'role': 'assistant'}]