This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'All of the following are true about HMG CoA reductase inhibitors except: \nSelect and explain. \nA. CNS accumulation of simvastatin and lovastatin is high and less for pravastatin and fluvastatin, B. Simvastatin is rapidly and pravastatin  is least metabolized., C. Bioavailability is minimally modified when pravastatin is taken with food, D. Fibrinogen levels are increased by pravastatin', 'role': 'user'}, {'content': 'Answer: D \nExplanation: None', 'role': 'assistant'}]