This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Gastro Intestinal System, Subject name: Pediatrics
[{'content': 'In a child with acute liver failure, the most important abnormal serum biochemical test that indicates poor prognosis: \nSelect and explain. \nA. Increasing transaminases, B. Increasing bilirubin, C. Increasing prothrombin time, D. Reversal of serum albumin-globulin ratio', 'role': 'user'}, {'content': "Answer: C \nExplanation: C. Increasing prothrombin time(Ref: Nelson's 20/e p 1967)Hepatic synthetic function is reflected in serum albumin and protein levels and in the PT or INRUnresponsiveness of PT to vitamin K suggests severe hepatic diseasePersistently low levels of factor VII are evidence of a poor prognosis in fulminant liver diseaseSerum aminotransferase activities do not correlate well with the severity of the illness.", 'role': 'assistant'}]