This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Medicine
[{'content': 'rtPA is NOT a contraindication in stroke with \nSelect and explain. \nA. BP >185/110 mm Hg, B. Heparin in the past 24 hrs, C. Coma, D. Lesion occupying >1/3 of middle cerebral artery territory', 'role': 'user'}, {'content': 'Answer: C \nExplanation: (C) Coma # rtPA (Alteplase) is indicated in pulmonary embolism, myocardial infarction, and stroke.> rtPA therapy in patients with stroke is contraindicated in certain situations like suspicion of subarachnoid hemorrhage on pretreatment evaluation, recent (within 3 months) intracranial or intraspinal surgery, history of intracranial hemorrhage, uncontrolled hypertension at time of treatment, active internal bleeding, known bleeding diathesis (eg, current use of oral anticoagulants, administration of heparin within 48 hours of onset of stroke), platelet count <100,000/mm3.', 'role': 'assistant'}]