This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anaesthesia, Subject name: Pharmacology
[{'content': 'Pancuronium differs from tubocurarine in that: \nSelect and explain. \nA. It is a depolarizing blocker, B. Its action is not reversed by neostigmine, C. It can cause rise in BP on rapid I.V. injection, D. It causes marked histamine release', 'role': 'user'}, {'content': 'Answer: C \nExplanation: * Pancuronium possesses vagolytic activity and can cause hypeension and tachycardia on rapid i.v. injection. * Pancuronium is a competitive NM blocker (Non-depolarizing NM blocker). Its actions can be reversed by anticholinesterases like neostigmine. * Unlike d-TC, histamine release is not seen with pancuronium.', 'role': 'assistant'}]