This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T., Subject name: Medicine
[{'content': 'Which of the following is true for plummer vinson syndrome true is - \nSelect and explain. \nA. Oesophageal web of lower oesophagus, B. Megaloblstic anemia is a feature, C. It increases risk of squamous cell carcinoma of oesophagus, D. It increases risk of adenocarcinoma of oesophagus', 'role': 'user'}, {'content': "Answer: C \nExplanation: Ans. is 'c' i.e., It increases risk of squamous cell carcinoma of oesophagus Plummer-Vinson syndrome* Plummer-Vinson syndrome, also known as Brown-Kelly-Paterson syndrome or sederopenic dysphagia, seen in middle aged edentulous women.* The plummer Vinsion Paterson Brown Kelly Syndrome is characterized by: -# Dysphagia# Chronic iron deficiency anemia# Atrophic oral mucosa and glossitis# Brittle, spoon-shaped fingernails (Koilonychia)* The cause of dysphagia is usually a cervical esophageal web, but abnormal pharyngeal and esophageal motility may play a role.* The syndrome characterstically occurs in middle aged edentulous (without teeth) women.* It is a premalignant lesion. Approximately 10% of patient develop squamous cell Ca of esophagus, oral cavity or the hypopharynx.* As iron-deficiency anemia is a common finding, it is also known as sideropenic dysphagia.* Carcinoma develops in post-cricoid region.", 'role': 'assistant'}]