This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': "A high grade squamous intraepithelial lesion is noted with pap, next management includes - \nSelect and explain. \nA. Wahim's hysterectomy, B. Local excision, C. Colposcolic study and biopsy, D. HPV DNA testing", 'role': 'user'}, {'content': "Answer: C \nExplanation: Ans' is'c'i.e., Colposcolic study and biopsyFor high grade intraepithelial lesions (HSIL), first step is to do colposcopy and biopsy. Moderate to severe dysplasia(CIN-II & CIN-III) (HSIL):Treatment options are:Local destructive methodsCryosurgeryFulguration/electrocoagulation .Laser ablationExcision of abnormal tissueCold knife conisationLaser conisationLLETZLEEPNETZSurgery:Therapeutic conisationHysterectomyHysterectomy with removal of vaginal cuff if carcinoma in situ extends into vaginal vault", 'role': 'assistant'}]