This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunology, Subject name: Microbiology
[{'content': 'Skin test demonstrates all types of hypersensitivity except: \nSelect and explain. \nA. Type 1, B. Type 2, C. Type 3, D. Type 4', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans: b (type 2)Ref: Kuby's Immunology, 6th ed. Pg. 371-396.Hypersensitivity* Type I hypersensitivity - Ig E mediated- Causes systemic anaphylaxis and localized atopy- Detection includes skin testing by intradermal injection or by superficial scratching which helps in screening of allergens* Type II hypersensitivity- antibody mediated cytotoxicity- Causes transfusion reactions, haemolytic disease of newborn, drug induced haemolytic anaemia etc- No skin test is used for detection* Type II hypersensitivity- immune complex mediated- Causes arthus reaction and serum sickness- It can be as a result of injection of antigen* Type IV hypersensitivity - delayed type- Contact dermatitis, granuloma etc- Can be detected by skin tests and patch tests.", 'role': 'assistant'}]