This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Which of the following is caused by defective tyrosine metabolism? \nSelect and explain. \nA. Richner-Hanha syndrome, B. Neonatal tyrosinemia, C. Alkaptonuria, D. All of the above', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Metabolic diseases of tyrosine catabolism include tyrosinosis, Richner-Hanha syndrome, neonatal tyrosinemia, and alkaptonuria. Ref: Harper 28th edition, chapter 29.', 'role': 'assistant'}]