This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'HMG-CoA can be directly conveed to all except? \nSelect and explain. \nA. Acetoacetate, B. Acetyl-CoA, C. Mevalonate, D. Aceto-acetyl CoA', 'role': 'user'}, {'content': "Answer: D \nExplanation: Ans. is 'd' i.e., Aceto-acetyl CoA Acetoacetate & Acetyl - CoA are derived from HMG-CoA during ketogenesis by HMG-CoA lyase which breaks the HMG-CoA into acetoacetate and acetyl-CoA during ketogenesis.Mevalonate is formed directly from HMG-CoA in cholesterol synthesis.HMG-CoA is conveed to mevalonate by HMG-CoA reductase, the key regulatory enzyme of cholesterol synthesis.", 'role': 'assistant'}]