This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Rate of newly synthesized osteoid mineralization can be best estimated by: \nSelect and explain. \nA. Tetracycline labeling, B. Alizarin Red stain, C. Calcein stain, D. Von kossa stain', 'role': 'user'}, {'content': "Answer: A \nExplanation: Tetracycline labeling is a type of bone label study used to estimate rate of newly synthesized osteoid mineralization. It is most commonly and widely used method. Ref: 'Target Organ Pathology' By Hooson, (1997), Page 270; Harrison's Principles of Internal Medicine, 16th Edition, Page 2223; Bone Research Protocols, (2003), Page 305", 'role': 'assistant'}]