This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Adult polycystic kidney disease is inherited: March 2005 \nSelect and explain. \nA. X-linked dominant, B. X-linked recessive, C. Autosomal recessive, D. Autosomal dominant', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans. D: Autosomal dominant Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common inherited disorders. It is the most frequent genetic cause of renal failure in adults, It is a multisystemic and progressive disorder characterized by the formation and enlargement of cysts in the kidney and other organs (e.g., liver, pancreas, spleen). Clinical features usually begin in the third to fouh decade of life, but cysts may be detectable in childhood and in utero. Some other autosomal dominant disorders: Huntington chorea Neurofibromatosis Myotonic dystrophy Hereditary spherocytosis Marfan syndrome Osteogenesi imperfect Achondroplasia', 'role': 'assistant'}]