This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General anatomy, Subject name: Anatomy
[{'content': 'Endothelial leukocyte interaction during inflammation is mediated by \nSelect and explain. \nA. Selectins, B. Integrins, C. Defensins, D. Endothelin', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ref Robbins 9/e p76 Endothelial leucocytes interaction is also mediated by integrins Integrins are proteins that function mechanically, by attaching the cell cytoskeleton to the extracellular matrix (ECM), and biochemically, by sensing whether adhesion has occurred. The integrin family of proteins consists of alpha and beta subtypes, which form transmembrane heterodimers', 'role': 'assistant'}]