This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Medicine
[{'content': 'Which one of the following laboratory tests differentiates leukemoid reaction from chronic myeloid leukemia? \nSelect and explain. \nA. LAP (leukocyte alkaline phosphatase), B. LCA (leukocyte common antigen), C. MPO (myelo-peroxidase), D. TRAP (tarate resistant alkaline phosphatase)', 'role': 'user'}, {'content': 'Answer: A \nExplanation: <p>Leucocyte alkaline phosphate score in the cytoplasm of mature neutrophils in leukamoid reaction is characteristically high & ia very useful to distinguish it from CML. Leukaemoid reaction is defined as reactive excessive leucocytosis in response to infections,intoxication ,malignant disease ,& in severe hemmorhage & hemolysis.So mature neutrophils will be more resulting in elevated LAP.But in CML,mature neutrophils will be reduced resulting in low LAP score. </p><p>Reference :Harsh mohan textbook of pathology sixth edition pg no 353.</p>', 'role': 'assistant'}]