This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Pharmacokinetics, Subject name: Pharmacology
[{'content': 'Isoniazide is metabolized by - \nSelect and explain. \nA. Acetylation, B. Oxidation, C. Reduction, D. Hydrolysis', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Acetylation o Isoniazid is extensively metabolized in liver most important pathway being N - acetylation by NAT 2. The acetylated metabolite is excreted in urine.Drugs metabolized bv acetylationo Sulfonamides (including dapson)o INHo Procainamideo Hydralazineo PASo Clonazepam {given in 6th/e)", 'role': 'assistant'}]