This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'In patients with decompensated cirrhosis on diuretic therapy with tender gynaecomastia the best diuretic to substitute is: \nSelect and explain. \nA. Amiloride for spironolactone, B. Furosemide for spironolactone, C. Spironolactone for amiloride, D. Torsemide for spironolactone', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Amiloride (10-40 mg/day) can be substituted for spironolactone in patients with tender gynecomastia. Amiloride is more expensive and less effective Ref: HEPATOLOGY, June 2009', 'role': 'assistant'}]