This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous (Gynae), Subject name: Gynaecology & Obstetrics
[{'content': 'Which one of the following is used for Severe male factor infertility? \nSelect and explain. \nA. GIFT, B. ZIFT, C. ICSI, D. IVF', 'role': 'user'}, {'content': 'Answer: C \nExplanation: (C) ICSI# In cases of severe male factor infertility in which sperm count is low, a sperm cannot fertilize an egg, or the sperm has to be surgically retrieved, intracytoplasmic sperm injection (ICSI) is a highly effective solution.> ICSI involves the insertion of a single sperm directly into a mature egg obtained from the ovary of a woman undergoing in-vitro fertilization (IVF). Often, this procedure results in the fertilization and development of a normal embryo.> If ICSI is combined with IVF to improve the sucess rates.> GIFT (gamete intrafallopian transfer) and ZIFT (zygote intrafallopian transfer) are modified versions of in vitro fertilization (IVF).', 'role': 'assistant'}]