This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Tuberculosis, Subject name: Medicine
[{'content': 'XDR-TB is defined as: \nSelect and explain. \nA. Resistance to at least INH & rifampicin +/- other drugs, B. Resistance to any of the 3 first line drugs, C. Resistance to all 1st line drugs & any 3 second line injectable drugs, D. Resistance to at least INH & rifampicin + any quinolones + at least 1 injectable 2nd line drug', 'role': 'user'}, {'content': 'Answer: D \nExplanation: XDR -TB - resistant to - (1) INH & rifampicin (2) Any fluoroquinolone (3) 1 of 3 injectable drug (Amikacin, kanamycin or Capreomycin) MDR-TB - Resistance to INH & Rifampicin.', 'role': 'assistant'}]