This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of nucleic acids, Subject name: Biochemistry
[{'content': 'Lesh Nyhan syndrome is associated with deficiency of \nSelect and explain. \nA. HGP (paial), B. HGP (total), C. PRPP (paial), D. PRPP (total)', 'role': 'user'}, {'content': "Answer: B \nExplanation: REF :DM VASUDEVAN TEXTBOOK :7th EDITION ;Page no :403 Disease deficient enzyme GPD Deficiency G6PD Gaucher's disease beta glucosidase Lesch-Nyhan syndrome HGPase", 'role': 'assistant'}]