This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Complement system, Subject name: Pathology
[{'content': 'A 25-year-old woman presents with a history of recurrent shoness of breath and severe wheezing. Laboratory studies demonstrate that she has a deficiency of C1 inhibitor, an esterase inhibitor that regulates the activation of the classical complement pathway. What is the diagnosis? \nSelect and explain. \nA. Chronic granulomatous disease, B. Hereditary angioedema, C. Myeloperoxidase deficiency, D. Selective IgA deficiency', 'role': 'user'}, {'content': 'Answer: B \nExplanation: =Deficiency of C1 inhibitor, with excessive cleavage of C4 and C2 by C1s, is associated with the syndrome of hereditary angioedema. Feature:- Episodic Painless Non-pitting edema of soft tissues. =Chronic granulomatous disease (choice A) is due to a hereditary deficiency of NADPH oxidase. =Myeloperoxidase deficiency (choice C) increases susceptibility to infections with Candida. =Selective IgA deficiency (choice D) and Wiskott-Aldrich syndrome are congenital immunodeficiency disorders associated with defects in lymphocyte function', 'role': 'assistant'}]