This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Antimetabolites and Quinolones, Subject name: Pharmacology
[{'content': 'A contraindication to the use of ciprofloxacin is a history of: \nSelect and explain. \nA. Epilepsy, B. Deep vein thrombosis, C. Gout, D. G-6 PD deficiency', 'role': 'user'}, {'content': 'Answer: A \nExplanation: * Ciprofloxacin is contraindicated with NSAIDs because this combination results in increased risk of seizures. * It is also contra-indicated with theophylline because it increases the risk of theophylline toxicity by inhibiting its metabolism. * It is contra-indicated in pregnancy because it increases the risk of cailage damage in newborn.', 'role': 'assistant'}]