This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Pharmacology
[{'content': 'Drug of choice for nephrogenic diabetes insipidus is:- \nSelect and explain. \nA. Mannitol, B. Spironolactone, C. Thiazides, D. Demeclocycline', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Diabetes insipidus Central Nephrogenic Desmopressin (DOC) Thiazides (DOC) (As endogenous ADH is already present that is not able to work, so there is no point in giving ADH(desmopressin))', 'role': 'assistant'}]