This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'led maternal serum a-FP is seen in : \nSelect and explain. \nA. Multiple pregnancy, B. Trisomy 21, C. Open neural tube defect, D. IUD', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans. is b i.e. Trisomy 21 Low levels of MSAFP (Maternal serum alpha feto protein) are seen in : Chromosomal trisomy Gestational trophoblastic diseases Blighted ovum Increased maternal weight Overestimated gestational age. Note : The list given in the Williams Obs. 23/e, p 291 - Includes fetal death both in causes of increased and decreased AFP. But Fernando Arias 2/e, p 38 specifically includes - IUD in the causes of increased AFP and Blighted ovum /Aboion in the causes of decreased AFP.', 'role': 'assistant'}]