This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Pathology
[{'content': '. Primary biliary cirrhosis is positive for \nSelect and explain. \nA. PANCA, B. Anti-mitochondrial antibody, C. Anti nuclear antibody, D. Anti-microsomal antibody', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Primary Biliary Cirrhosis(PBC) - A progressive autoimmune liver disease characterised by non suppurative, inflammatory destruction of intra hepatic bile ducts. Characteristic autoantibody detected in primary biliary cirrhosis is antimitochondrial antibody Consequences: bile duct destruction-impaired secretion of bile, cholestasis, and inflammatory reaction in the poal tract-hepatic damage, fibrosis- cirrhosis and liver failure. SYSTEMIC AND GENERAL PATHOLOGY RAMDAS NAYAK PG NO 461 IMAGE REF:', 'role': 'assistant'}]