This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Not a specific tumor marker is - \nSelect and explain. \nA. CD 99, B. HMB 45, C. b- globulin, D. CEA', 'role': 'user'}, {'content': "Answer: D \nExplanation: Ans is 'd' i.e., CEA Carcinoembryonic antigen (CEA) is used as tumor marker for colorectal cancer (major use), lung cancer, breast cancer and ovarian cancer.It is alsoincreased in non-neoplastic conditions like alcoholic cirrhosis, hepatitis, IBD (CD, UC), smoking and pancreatitis.CEA lacks sensitivity as well as specificity, hence cannot be used to confirm the diagnosis.About other optionsCD 99 - specific marker for Ewing's sarcomaHMB 45 - specific marker for malignant melanomab - globulin - specific marker for multiple myeloma", 'role': 'assistant'}]