This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Pancreas, Subject name: Surgery
[{'content': 'Most common mutation in pancreatic adenocarcinoma:- \nSelect and explain. \nA. K-ras, B. p16, C. p53, D. BRAF', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ca-Pancreas MC genetic mutation in Ca pancreas/ Cholangiocarcinoma - K-RAS > p-16 MC genetic mutation in Ca- GB - P53 > K-RAS MC genetic mutation in Ca stomach - P53 > COX - II', 'role': 'assistant'}]