This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Commonest histological finding in benign hypertension is - \nSelect and explain. \nA. Proliferative endarteritis, B. Necrotizing arteriolitis, C. Hyaline arteriosclerosis, D. Cystic medial necrosis', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Hyaline arteriosclerosis consists of homogeneous pink hyaline thickening of the wall of the arterioles with loss of\xa0underlying structural detail.\nEncountered frequently in elderly patients whether normotensive or hypertensive, hyaline arteriosclerosis is more\xa0generalized and more severe in patients with hypertension.\nIt is also common in diabetes as a part of the characteristic microangiopathy.\n\nPathogenesis\n\nThe lesion reflects leakage of plasma components across vascular endothelium and excessive extracellular\xa0matrix production by smooth muscle cells secondary to the chronic hemodynamic stress of hypertension or a\xa0metabolic stress in diabetes that accentuates endothelial cell injury.\n\nAlso, know\nHyperplastic arteriosclerosis\n\nIt is characteristic of malignant hypertension.\nThere is concentrically laminated thickening of arteriolar wall → onion thickening.\nThere is mucinous intimal thickening and fibrous intimal thickening.\nThere may be accompanied fibrinoid deposited with necrosis of the vessel wall → fibrinoid necrosis.', 'role': 'assistant'}]