This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Gastro Intestinal System, Subject name: Pediatrics
[{'content': "Which of these disorders in neonates can best be excluded or diagnosed by anorectal manometry? \nSelect and explain. \nA. Hypertrophic pyloric stenosis, B. Duodenal atresia, C. Meconium plug syndrome, D. Hirschsprung's disease", 'role': 'user'}, {'content': "Answer: D \nExplanation: Ans. D. Hirschsprung's diseaseAnorectal manometry should ideally be performed in all newborns with symptoms of lower bowel obstruction. This technique is useful in assessment of changes in anal pressure which are recorded during and after rectal distention. It is most helpful for diagnosing or excluding Hirschsprung's disease.", 'role': 'assistant'}]