This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
[{'content': 'Not true regarding Waldenstrom&;s macroglobulinemia, \nSelect and explain. \nA. Lymphadenopathy is usually present, B. Blood viscosity increased, C. Ig M immunoglobulin increased, D. Hypercalcemia', 'role': 'user'}, {'content': "Answer: D \nExplanation: WALDENSTROM'S MACROGLOBULINEMIAIt is a malignancy of lymphoplasmacytoid cells that secreted IgM. In contrast to myeloma, the disease was associated with lymphadenopathy and hepatosplenomegaly, but the major clinical manifestation was hyperviscosity syndrome.Reference: Harrison&;s principles of Internal Medicine; 19th edition; Chapter 136 Plasma Cell Disorders", 'role': 'assistant'}]