This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hematology: White Blood Cells (Miscellaneous questions), Subject name: Pathology
[{'content': 'Dohle bodies can be seen in which of the following? \nSelect and explain. \nA. Plasma cell myeloma, B. Sepsis, C. Chronic granulomatous disease, D. Rheumatoid ahritis', 'role': 'user'}, {'content': 'Answer: B \nExplanation: In sepsis or severe inflammatory disorders (e.g., Kawasaki disease), leukocytosis is often accompanied by morphologic changes in neutrophils, such as toxic granulations, Dohle bodies, and cytoplasmic vacuoles Toxic granules are coarser and darker than normal neutrophilic granules, represent abnormal azurophilic (primary) granules Dohle bodies are patches of dilated endoplasmic reticulum that appear as sky-blue cytoplasmic "puddles."', 'role': 'assistant'}]