This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cytotoxic Anticancer Drugs, Subject name: Pharmacology
[{'content': 'All are true statements about anticancer drugs except? \nSelect and explain. \nA. Vincristine is a marrow sparing anticancer drug, B. Irinotecan is a topoisomerase II inhibitor, C. L-asparaginase can cause acute pancreatitis, D. Anthracyclines cause cardiotoxicity', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Anthracyclines cause cardiotoxicity, prevented by dexrazoxane Bleomycin causes pulmonary fibrosis L-asparaginase cause allergy, acute pancreatitis Vincristine, vinblastine causes peripheral neuropathy & SIADH. But it is marrow sparing. Irinotecan is a topoisomerase I inhibitor used for colorectal carcinoma Topoisomerase II inhibitors are Etoposide, doxorubicin, Daunorubicin & anthracyclines.', 'role': 'assistant'}]