This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Bacterial infection, Subject name: Medicine
[{'content': 'Interferon gamma release assay measures IFN release against which M.TB antigen: \nSelect and explain. \nA. ESAT 6, B. ESAT 7, C. CF 11, D. CF 12', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Interferon gamma release assay (IGRA) measure T cell release of gamma interferon against TB antigen ESAT 6 and CF 10. This test also called as Quantiferon- more specific than Tuberculin skin testing as a result of less cross reactivity due to BCG vaccination and sensitization by nontuberculosis mycobacteria. - It reduces patient visits and gives an ability to perform serial testing without the hassle of boosting phenomenon caused by Tuberculin skin testing.', 'role': 'assistant'}]