This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Urology, Subject name: Surgery
[{'content': 'The neo-adjuvant chemotherapy indicated in oesophageal carcinoma \nSelect and explain. \nA. Cisplatin, B. Doxorubicin, C. Mitomycin C, D. 5-FU-Leucovarin', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Treatment of CA esophagus High-grade dysplasia (Tis) or T1a Endoscopic mucosal resection Localised advanced cancer T1: Vagal sparing or transhiatal or minimal invasive esophagectomy with limited LN dissection T2 and T3: Neoadjuvant Chemoradiation + surgery Cervical SCC or Non-ideal candidate for resection : Definitive chemoradiation Locally advanced cancer Chemoradiation (+- surgical resection in T4a) Metastatic disease Definitive chemoradiation (for involved distant LN or metastatic disease) Malignant TEF Coated SEMS (Self expanding metallic stents) Chemotherapy regimen : Epirubicin + Cisplatin + 5-FU Ref: Shackelford 7th edition Pgno : 438-448', 'role': 'assistant'}]