This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Desmoplakin is the target antigen in: \nSelect and explain. \nA. Pemphigus vulgaris, B. Drug induced pemphigus, C. Paraneoplastic pemphigus, D. Pemphigus foliaceous', 'role': 'user'}, {'content': "Answer: C \nExplanation: Paraneoplastic pemphigus is a severe variant of pemphigus, associated with an underlying neoplasm -\xa0most frequently non hodgkin's lymphoma, chronic lymphocytic leukemia, thymoma, and castleman\xa0 disease. Tumor antigens are hypothesized to evoke an immune response that leads to the\xa0development of an autoimmune response to intercellular adhesins (plakins). This autoantibody\xa0response leads to blistering in mucosa and other epithelia.\nRef: Neville's\xa0oral and maxillofacial pathology 4th edition page 717-718", 'role': 'assistant'}]