This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Preoperative assessment and monitoring in anaesthesia, Subject name: Anaesthesia
[{'content': 'A cirrhotic patient with abnormal coagulation studies due to hepatic synthetic dysfunction requires an urgent cholecystectomy. A transfusion of FFP is planned to minimize the risk of bleeding due to surgery. What is the optimal timing of this transfusion? \nSelect and explain. \nA. The day before surgery, B. The night before surgery, C. On call to surgery, D. Intraoperatively', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Transfusions with FFP to replenish vitamin K-dependent clotting factors should be administered on call to the operating room. The timing of transfusion is dependent on the quantity of each factor delivered and its half-life. The half-life of the most stable clotting factor, factor VII, is 4 to 6 hours. Thus, transfusion of FFP on call to the operating room ensures that the transfusion is complete prior to the incision, with circulating factors to cover the operative and immediate postoperative period.', 'role': 'assistant'}]