This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'The phenomenon where subsequent generations are at risk of earlier and more severe disease, is known as - \nSelect and explain. \nA. Anticipation, B. Pleiotrophy, C. Imprinting, D. Mosaicism', 'role': 'user'}, {'content': 'Answer: A \nExplanation: . Anticipation', 'role': 'assistant'}]