This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'In the presence of renal failure.............. should not be given - \nSelect and explain. \nA. Furosemide, B. Bumetanide, C. Spironolactone, D. None', 'role': 'user'}, {'content': "Answer: C \nExplanation: Ans. is 'c' i.e., Spironolactone In renal failure loop diuretics (Furosemide, Bometanide. Torasemide) are DOC. Thiazides are ineffective in renal failure. Spironolactone can cause dangerous hyperkalemia if renal function is inadequate.", 'role': 'assistant'}]