This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': 'The Finnish type of congenital nephritic syndrome occurs due to gene mutation affecting the following protein – \nSelect and explain. \nA. Podocin, B. Alpha–actinin, C. Nephrin, D. CD2 activated protein', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Congenital nephrotic syndrome\n\nInfant who develop nephrotic syndrome within the first 3 months of life are considered to have congenital nephrotic syndrome.\nThe most common cause of this syndrome is finnish-type congenital nephrotic syndrome, an autosomal recessive disorder.\nTwo most common genes involved are -\ni)\xa0NPHS1\xa0 \xa0 -->\xa0 Coding for nephrin and results in finnish-type nephrotic syndrome.\n\nii) NPHS2 --> Coding for Podocin and results in FSGS.\nOther important genes involved in steroid - resistant nephrotic syndrome', 'role': 'assistant'}]