This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'All are TRUE about myxomas in hea, EXCEPT: \nSelect and explain. \nA. Most common primary tumor of the hea, B. Associated with clonal abnormalities of chromosomes 12 and 17, C. 90% are located in the atria, D. Never occur on hea valves', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Myxomas are the most common primary tumor of the hea in adults. They are benign neoplasms often associated with clonal abnormalities of chromosomes 12 and 17 that are thought to arise from primitive multipotent mesenchymal cells. Although they may arise in any of the four chambers or, rarely, on the hea valves, about 90% are located in the atria (atrial myxomas), with a left-to-right ratio of approximately 4 : 1. Ref: Robbins 8th edition Chapter 12.', 'role': 'assistant'}]