This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pharmacology
[{'content': 'Which of the following associated with the highest cardiac moality \nSelect and explain. \nA. Rofecoxib, B. Nicorandil, C. Losaan, D. Metaprolol', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Refer kDT 6/e p 534 Angiotensin receptor blocker like losaan and Beta blocker like my temporal all are cardioprotective in congestive hea failure. This decrease the moality Nicorandil is a potassium channel openers used in angina. It is cardioprotective in causing ischaemic preconditioning Rofecoxib is a selective COX 2 inhibitors. That was withdrawn due to increased risk of myocardial infarction', 'role': 'assistant'}]