This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'What is the effect of progesterone on lipids? \nSelect and explain. \nA. Lowers LDL, increases HDL, B. Lowers HDL and increases LDL, C. Lowers HDL and lowers LDL, D. Increases LDL and lowers HDL', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Progesterone tend to lower HDL level. The mechanism appears to involve an increase in (Hepatic lipase)HL activity. It also decreases triglycerides and modestly lowers LDL levels due to decreased production of VLDL apoB. Ref: Principles and Practice of Endocrinology and Metabolism, 3e.', 'role': 'assistant'}]