This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Which of the following is true about Digoxin \nSelect and explain. \nA. It acts by inhibiting PDE 3, B. Dose reduction is not required in liver failure, C. Hyperkalemia predisposes to Digoxin toxicity, D. Atrial flutter is the most characteristic arrhythmia caused by Digoxin toxicity', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Digoxin acts by inhibiting Na+- K+ ATPase.\nDose reduction is required in renal failure not liver failure.\nHypokalemia increases the risk of Digoxin toxicity.\nMost common arrhythmia in\xa0Digoxin toxicity is most ventricular bigeminy.\nMost characteristic arrhythmia seen in Digoxin toxicity is Atrial tachycardia + AV Nodal blockade.', 'role': 'assistant'}]