This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: NSAIDs, Gout and Rheumatoid Ahritis, Subject name: Pharmacology
[{'content': 'True statement about cyclooxygenase -2 is: \nSelect and explain. \nA. It is not inhibited by indomethacin, B. It is inducible, C. It generates cytoprotective prostaglandins in gastric mucosa, D. It is found only in fetal tissues', 'role': 'user'}, {'content': 'Answer: B \nExplanation: COX-1 is a house-keeping enzyme that is responsible for the generation of gastroprotective PGs. COX-2 is an inducible enzyme whose production is markedly increased at inflammatory sites. Indomethacin is a nonselective inhibitor of both isoforms of COX.', 'role': 'assistant'}]