This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Surgery
[{'content': 'Meconium ileus is associated with: \nSelect and explain. \nA. Fibrocystic disease of pancreas, B. Liver aplasia, C. Cirrhosis of liver, D. Malnutrition', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Meconium ileus in the newborn represents the earliest clinical manifestation of CF and affects roughly 15% of patients with this inherited disease Cystic FIbrosis Diagnosis The diagnosis of CF is usually confirmed in the postoperative period The pilocarpine iontophoresis sweat test revealing a chloride concentration >60mEq/L is the most reliable and definitive method to confirm the diagnosis of CF. This test may not be reliable in infants and is usually performed later. A more immediate test includes detection of the mutated CFTR gene. This test, coupled withh a careful family history and clinical presentation, permits confirmation of the diagnosis in most infants Ref: Sabiston 20th edition Pgno: 1875', 'role': 'assistant'}]