This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Pathology
[{'content': 'Hormone Replacement Therapy(H) in postmenopausal women is beneficial in all these Except \nSelect and explain. \nA. Vasomotor symptoms, B. Osteoporosis, C. Prevention of CAD, D. Vaginal atrophy', 'role': 'user'}, {'content': "Answer: C \nExplanation: Hormone Replacement TherapyEstrogen is the most effective treatment available for relief of the menopausal symptoms that many women experience, including hot flashes, vaginal dryness, urinary symptoms, and emotional lability.Women&;s Health Initiative showed no cardiovascular benefit with unopposed estrogen and a smallincrease in risk with combined therapy.Estrogen is an option for the prevention of osteoporosis inperimenopausal women, estrogen-progesterone therapy reduces fracture risk at a cost of increase in the incidence of breast cancer, coronary hea disease, stroke and venous thromboembolism, or in the case unopposed estrogen, an increase in stroke and thromboembolism.Post-menopausal hormone therapy, either unopposed estrogen or combined estrogen-progestin therapy should not be initiated for prevention of CHD.Bisphosphonates or raloxifene are recommended as first-line drugs for prevention and bisphosphonates for treatment of established osteoporosis.(Refer: Novak's Textbook of Gynaecology, 14th edition, pg no- 1330-1333)", 'role': 'assistant'}]