This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Which of the following organelles plays a pivotal role in Apoptosis: \nSelect and explain. \nA. Mitochondria, B. Endoplasmic Reticulum, C. Nucleus, D. Golgi Apparatus', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Initiation of apoptosis occurs through two different pathways, intrinsic mitochondria pathway and extrinsic death receptor mediated pathway. Mitochondria plays active role in apoptosis. Ref: Tanley L. Robbins, Ramzi S. Cotran, (2012) , Chapter 1, "Cell Injury", In the book, "Pocket Companion to Robbins and Cotran Pathologic Basis of Disease", 8th Edition, USA, Page 27; Robbin\'s Basic Pathology, 7th Edition, Pages 28, 29; Essential of Apoptosis (2003), Page 245', 'role': 'assistant'}]