This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Urinary tract, Subject name: Anatomy
[{'content': 'Gene for Wilms tumor iis located on \nSelect and explain. \nA. Chromosome 1, B. Chromosome 10, C. Chromosome 11, D. Chromosome 12', 'role': 'user'}, {'content': 'Answer: C \nExplanation: characterized by Wilms tumor, aniridia, genital anomalies, and mental retardation. Their lifetime risk of developing Wilms tumor is approximately 33%. Individuals with WAGR syndrome carry constitutional (germline) deletions of 11p13. Studies on these patients led to the identification of the first Wilms tumor-associated gene, WT1, and a contiguously deleted autosomal dominant gene for aniridia, PAX6, both located on chromosome 11p13. Patients with deletions restricted to PAX6, with normal WT1 function, develop sporadic aniridia, but they are not at increased risk for Wilms tumors Refer Robbins 9/e 481', 'role': 'assistant'}]