This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Uveal tract, Subject name: Ophthalmology
[{'content': 'Brushfield spot in iris is seen in - \nSelect and explain. \nA. Neurofibromatosis, B. Down syndrome, C. Tuberous sclerosis, D. Toxoplasmosis', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Brushfield spots are seen in Down syndrome. Pedunculated nodules are seen in Neurofibromatosis.', 'role': 'assistant'}]