This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': "All are causes of acute tubulointerstitial nephritis except: \nSelect and explain. \nA. Methicillin, B. Sjogren syndrome, C. SLE, D. Down's syndrome", 'role': 'user'}, {'content': 'Answer: D \nExplanation: Acute Tubulointerstitial Disorders\nTherapeutic agents \n\nAntibiotics (Beta-lactams, sulfonamides, quinolones, vancomycin, erythromycin, minocycline, rifampin, ethambutol, acyclovir)\nNonsteroidal anti-inflammatory drugs, COX-2 inhibitors\nDiuretics (rarely thiazides, loop diuretics, triamterene)\nAnticonvulsants (phenytoin, valproate, carbamazepine, phenobarbital)\nMiscellaneous (proton pump inhibitors, H2 blockers, captopril, mesalazine, indinavir, allopurinol}\n\nInfection \n\nBacteria (Streptococcus, Staphylococcus. Legionella. Salmonella. Brucella. Yersinia. Corynebacterium- diphtheria)\nViruses (EBV, CMV, hantavirus, polyomavirus, HIV)\nMiscellaneous (Leptospira Rickettsia, Mycoplasma\n\nAutoimmune \n\nTubulointerstitial nephritis with uveitis (TINU)\nSjögren\'s syndrome\nSystemic lupus erythematosus\nGranulomatous interstitial nephritis\nlgG4-related systemic disease\nIdiopathic autoimmune interstitial nephritis\n\nAcute obstructive disorders \n\nLight chain cast nephropathy ("myeloma kidney”)\nAcute phosphate nephropathy\nAcute urate nephropathy', 'role': 'assistant'}]