This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Central Nervous system, Subject name: Pharmacology
[{'content': 'Which of the following diuretics decreases the renal lithium clearance? \nSelect and explain. \nA. Acetazolamide, B. Mannitol, C. Furosemide, D. Spironolactone', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ref: KDT 8TH ED. Loop diuretics and thiazides cause NA+ loss in the nephron, this leads to compensatory increase in reabsorption of Na+ and Li+ in the proximal tubules.', 'role': 'assistant'}]