This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Major source of collagen in cirrhosis - \nSelect and explain. \nA. Kupfer cells, B. Ito cell (Hepatic stellate cell), C. Hepatocyte, D. Canalicular cell', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., Ito cell (Hepatic stellate cell)o Perisinusoidal stellate cells (Ito cells) play a role in the storage and metabolism of vitamin A and are transformed into collegen producing myofibroblasts when there is inflamation of the liver. These cells are the major source of collegen in cirrhosis.", 'role': 'assistant'}]