This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'An elderly hypeensive has diabetes mellitus and bilateral renal aery stenosis. The best management is - \nSelect and explain. \nA. Enalapril, B. Verapami I, C. Beta blockers, D. Thiazides', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., Verapamil o ACE inhibitors are the most appropriate antihypeensives in patients with diabetes, nephropathy, left ventricular hyperophy, CHF, angina and post MI cases. o But ACE inhibitors are contraindicated in bilateral renal aery stenosis. o CCBs are next to ACE inhibitors in reducing albuminuria and slowing disease progression in diabetic nephropathy. o Therefore a CCBs (verapamil) should be given to this patient. Remember o Thiazide diuretic with added If+ sparing diuretic is the first choice treatment of essential hypeension.", 'role': 'assistant'}]