This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Anaesthesia
[{'content': 'Which of the are the following contraindication for halothane used – \nSelect and explain. \nA. Male sex, B. Middle age, C. Recent halothane use, D. Associated liver pathology', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Multiple exposures is the single most important factor for halothane hepatitis → Repeated use should be avoided, at least an interval of 3 months should be given between two exposures.\nObesity and middle age are risk factors for halothane hepatitis, but these are not contraindications.\nOption \'d\' requires specific mention here :-\n\n\xa0 \xa0 \xa0 \xa0 \xa0\xa0♦Pre-existing liver disease or jaundice is not a contraindication\xa0:-\n"There is no compelling evidence associating halothane with worsening of pre-existing liver disease".\n__ Morgan 4th/e 169\n"Pre-existing liver disease unrelated to halothane is not a contraindication to the use of halothane".\n__ Lee 13th/e 143\n\nLiver dysfunction & Jaundice to previous halothane exposure is a contraindication. Though not a contraindication, Halothane should be avoided in liver disease.', 'role': 'assistant'}]