This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Carbohydrates, Subject name: Biochemistry
[{'content': 'Which of the following disease occurs due to the deficiency of glucocerebroside? \nSelect and explain. \nA. Gaucher disease, B. Pompe disease, C. Fabry disease, D. Krabbe disease', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans: a (Gaucher disease) Ref: Vasudevan and Sreekumari, 4th ed.Gaucher disease is due to lack of glucocerebroside and substance accumulating is glucosyl ceramide.Lysosomal storage disorders/ sphingolipidosis/ lipid storage diseases:Disease Enzyme deficientSubstance accumulating * Pompe diseasea glucosidase (acid maltase)glycogen* Gaucher diseaseb glucocerebrosidaseglucosyl ceramide (cerebroside)* Fabrya galactosidaseglobotriaosyl ceramide (ceramyl trihexoside)* Krabbeb galactosidasegalactosyl ceramide* Niemann-Pick diseaseSphingomyelinaseGM1 gangliosidosis Glycogen storage disordersEnzyme deficient* Type I Von GirkeGlucose 6 phosphatase* Type II Pompe diseasea glucosidase* Coris (Forbes)Debranching enzyme* AndersonBranching enzyme* Me ArdleMuscle phosphorylase* Type IV Her diseaseLiver phosphorylase', 'role': 'assistant'}]