This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Urology, Subject name: Surgery
[{'content': 'Nigro protocol is for which carcinoma \nSelect and explain. \nA. Anal, B. Colon, C. Hepatocellular, D. Pancreatic', 'role': 'user'}, {'content': "Answer: A \nExplanation: Nigro protocol or Nigro Regime for Anal Carcinoma (Norman Nigro, et al 1974): \x02 * Initial radiotherapy for 3 weeks 3000 rads (30 Gy total) to perineum and pelvis \x02 * Then chemotherapy--5 FU, for 4-5 days; is a radiosensitizer, staed on 1st day of as 1000 mg/m2 continuous infusion. Mitomycin C is 15 mg/m2 as single dose on 1st day of \x02 * Later after 3 weeks abdominoperineal resection (APR) with colostomy in case of persistent or recurrent disease. Reference : page 987 SRB's manual of surgery 5th edition", 'role': 'assistant'}]