This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'The normal cellular counterpas of oncogenes are impoant for the following functions, except ? \nSelect and explain. \nA. Promotion of cell cycle progression, B. Inhibition of apoptosis, C. Promotion of DNA repair, D. Promotion of nuclear transcription', 'role': 'user'}, {'content': 'Answer: C \nExplanation: o Normal cellular counterpa of oncogene is protooncogene.o The functions of protooncogene is to code forGrowth factorsGrowth factor receptorsProteins involved in signal transductionNeuclear regulatory proteins (transcription factors)Cyclins/CDKso All these lead to cell proliferation and progression of cell cycle.o When any of these protooncogenes becomes oncogene by mutation / overexpression, there is uncontrolled proliferation of cell and development of cancer.This proliferation is autonomous, i.e. without physiological stimulus.', 'role': 'assistant'}]