This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.V.S, Subject name: Medicine
[{'content': 'Most common cause of death in adult with PDA is- 1. CCF 2.Infective endocarditis 3. Rupture 4. Embolism \nSelect and explain. \nA. only 1, B. Both 1 and 4, C. 1, 2 and 3, D. Both 1 and 2', 'role': 'user'}, {'content': 'Answer: C \nExplanation: The leading causes of death in adults with patent ductus are cardiac failure and infective endocarditis; occasionally severe pulmonary vascular obstruction may cause aneurysmal dilatation, calcification, and rupture of the ductus. ( Harrison&;s principle of internal medicine,18th edition,pg no. 1924)', 'role': 'assistant'}]