This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Which of the following is the most effective drug against M. leprae ? \nSelect and explain. \nA. Dapsone, B. Rifampicin, C. Clofazamine, D. Prothionamide', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Rifampicin is the only bactericidal drug amongst the anti leprosy drugs & can render Leprosy rapidly non contagious. It acts by inhibiting mycobacterial DNA dependent RNA synthesis. Ref: Essentials of Medical Pharmacology By KD Tripathi, 5th Edition, Pages 700, 709-11, 713.', 'role': 'assistant'}]