This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Virology (General Propeies, DNA Viruses), Subject name: Microbiology
[{'content': 'Acute Hepatitis B is indicated by: \nSelect and explain. \nA. HBsAg, B. HBcAg, C. HBeAg, D. Anti HBc (IgM)', 'role': 'user'}, {'content': "Answer: D \nExplanation: Acute Hepatitis B is indicated by Anti HBc (IgM). Markers of hepatitis B infection: HBsAg Epidemiological marker of hepatitis B infection. Earliest marker seen in infection. Also seen in chronic infection. HBcAg HBe Indicates active viral replication. Marker of infectivity for Hepatitis B. Anti-HBc First antibody to appear in serum. IgM anti-HBc is a marker of 'acute Hepatitis B'. IgG anti-HBc is a marker of ' chronic Hepatitis B'.", 'role': 'assistant'}]