This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'Memory impairment is most likely to occur in: \nSelect and explain. \nA. Downs Syndrome, B. Alkaptonuria, C. Attention deficit disorder, D. Conduct disorder', 'role': 'user'}, {'content': "Answer: A \nExplanation: Answer is A (Down's syndrome) Down Syndrome is associated with memory impairment. Adults with trisomy 21 (Down's) consistently develop the neuropathologic hallmark's of Alzheimer's disease of they survive beyond 40 years of age - Harrison 's The most noble aspect is down's syndrome is marked mental retardation, relatively poor expressive language and impaired verbal sho term memory' - Child and Adolescent Psychiatry", 'role': 'assistant'}]