This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Adrenergic System, Subject name: Pharmacology
[{'content': 'Timolol is contraindicated in: \nSelect and explain. \nA. Hypertension, B. Glaucoma, C. COPD, D. Aphakia', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans. (C) COPD(Ref: KDT 8th/e p160-161)Timolol is a non-selective b -blocker. It can prevent b2 mediated bronchodilation and thus worsen the condition in patients of bronchial asthma and COPD.', 'role': 'assistant'}]