This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Urinary tract, Subject name: Pathology
[{'content': 'Histology of Alpo syndrome- \nSelect and explain. \nA. Foamy cells in interstitium, B. Foamy cells in tubular epithelial cells, C. Thickening of GBM > 100 nm, D. Thinning of GBM < 100 nm', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Alpo syndrome: EM is diagnostic and shows "basket weave appearance" of the GBM. Alpo syndrome: Hereditary nephritis Abnormal a3 (COL4A3), a4 (COL4A4), or a5 (COL4A5) chain of type IV collagen Hematuria with progression to chronic renal failure Nerve deafness Eye disorders Foamy cells in the interstitium. Ref: RAM DAS NAYAK EXAM PREPARATORY MANUAL FOR UNDERGRADUATES 2nd ed. pg no: 612', 'role': 'assistant'}]