This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': 'True statement about inheritance of an X linked recessive trait is – \nSelect and explain. \nA. 50% of boys of carrier mother are affected, B. 50% of girls of diseased father arecarrier, C. Father transmits disease to the son, D. Mother transmits the disease to the daughter', 'role': 'user'}, {'content': "Answer: A \nExplanation: Features of X-linked disorders\n\nExcept for a few conditions, all X-linked disorders are X-linked recessive.\nA male has only one X-chromosome, the male with an affected gene on X-chromosome will always manifest the disease.\nOn the other hand, the female has 2 X-chromosomes, the heterozygous female will be a carrier because of the expression of a normal allele on the other X-chromosome.\nNote - Female with Turner syndrome (only one 'X' chromosome) can manifest X-linked recessive disorders.\n50% boys of the carrier mother\xa0will be affected.\nAll daughters of an affected father will become a carrier, i.e. affected father will transmit the defective X-chromosome to all the daughters.\nFather will not transmit the disease to son as boys do not inherit X-chromosome from father.", 'role': 'assistant'}]