This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'Regarding leflunomide in pregnancy all are true except \nSelect and explain. \nA. Cause hydrocephalus and skeletal anomalies in fetus, B. Pyrimidine synthesis inhibitor, C. Its active metabolite can be detected in plasma for upto 2 years after dis continuation, D. Used to treat Rheumatoid arthritis in pregnancy', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Leflunomide, is used to treat Rheumatoid arthritis, but is contraindicated in pregnancy.', 'role': 'assistant'}]