This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Ophthalmology
[{'content': 'In retinoblastoma, after enucleation, which tissue is sectioned to find out systemic metastasis \nSelect and explain. \nA. Central retinal aery, B. Sclera and episclera, C. Optic nerve, D. Voex vein', 'role': 'user'}, {'content': 'Answer: C \nExplanation: C i.e. Optic nerve Enucleation is indicated in large retinoblastoma with diffuse involvement (due to poor prognosis & high risk of recurrence) & normal fellow eye (so aggressive chemotherapy is inappropriate). It should be done with minimal-manipulation and it is imperative to obtain 8-12 mm piece of optic nerve Q to rule out any spread of tumor to brain.', 'role': 'assistant'}]