This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Other Respiratory Disorders, Subject name: Pediatrics
[{'content': 'A child is brought to the pediatric OPD with high grade fever of 24 hours duration. History reveals 3 episodes of chest infection and passage of foul smelling stools. The most probable diagnosis is: \nSelect and explain. \nA. Cystic fibrosis, B. Maple syrup urine disease, C. Bilirubin conjugation defect, D. Criggler Najar syndrome', 'role': 'user'}, {'content': "Answer: A \nExplanation: High grade fever and recurrent chest infection along with passage of foul smelling stools (steatorrhea) suggests a diagnosis of cystic fibrosis. In cystic fibrosis because of pancreatic exocrine insufficiency, foul smelling stool (steatorrhea) is common. Cystic fibrosis: Autosomal recessive disease Mutation in cystic fibrosis transmembrane conductor regulator (CFTR) gene on chromosome 7q There is defective transpo of chloride and not calcium in cystic fibrosis. C/F's: Recurrent respiratory infections Azoospermia and infeility Exocrine pancreatic insufficiency causing steatorrhea Recurrent acute/chronic pancreatitis Biliary cirrhosis Failure to thrive Salt depletion Vitamin deficiencies", 'role': 'assistant'}]