This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Chromosomal instability syndrome is \nSelect and explain. \nA. Fanconi syndrome, B. Ataxia Telangectasia, C. Bloom syndrome, D. All of the above', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Immunohistochemistry : Used in diagnosis of abnormal cells such as those found in tumors also used to understand the distribution and localization of biomarkers and differentially expressed protiens in different parts of a biological tissue.\nSouthern blotting : Used to detect DNA changes, e.g. whether genes have been deleted or rearranged. It is also used to detect RFLP. So it can detect gene expression.\nNorthern blotting : Used to detect RNA level. So used to analyze pattern and level of gene expression in different tissue.\nMicroarray : Can detect genomic changes as it measures many mRNA levels at once.', 'role': 'assistant'}]