This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'The Most common gene defect in "Idiopathic Steroid Resistant Nephrotic Syndrome": \nSelect and explain. \nA. ACE, B. NPHS 2, C. HOX 11, D. PAX', 'role': 'user'}, {'content': 'Answer: B \nExplanation: NPHS 2', 'role': 'assistant'}]