This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pharmacology
[{'content': 'Spironolactone should not be given with \nSelect and explain. \nA. Chlohiazide, B. Beta blockers, C. ACE inhibitors, D. Amlodipine', 'role': 'user'}, {'content': "Answer: C \nExplanation: Sprinolanctone is a potassium sparing diurectic It doesn't excrete potassium - increasing potassium levels in the blood ACE IN. also increases potassium levels in the blood Hence the combination is contraindicated Ref: KD Tripathi 8th ed", 'role': 'assistant'}]