This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Dental
[{'content': 'Not true about angioneurotic edema ? \nSelect and explain. \nA. Pitting edema of face, lips and mucous membrane, B. C1 Esterase inhibitor deficiency can cause it, C. Extreme temperature exposure can provoke it, D. Known with ACE inhibitors', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Edema of angineurotic-edema is\xa0non-pitting.\nC1\xa0esterase inhibitor deficiency can cause hereditary angioneurotic edema.\nAngioedema is a well known adverse effect of ACE inhibitors.', 'role': 'assistant'}]