This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'If a patient is on Warfarin and INR comes out to be 8. Next step would be to stop the drug and: March 2011 \nSelect and explain. \nA. Resta at a lower dose once the INR is in therapeutic range, B. Give oral Vitamin K1, C. Administer fresh frozen plasma, D. Transfuse fresh blood', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans. B: Give oral Vitamin K1 Vitamin K1 is the specific antidote for warfarin Treatment of bleeding due to oral anticoagulants consists of: Withhold the anticoagulant Give fresh blood transfusion; supplies clotting factors and replenishes ost blood. Alternatively fresh frozen plasma may be used as a source of clotting factors Give vit K1 (phytonadione)-specific antidote, but it takes 6-24 hours for the clotting factors to be resynthesized and released in blood after vit K administration.', 'role': 'assistant'}]