This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Medicine
[{'content': 'In a patient suffering from chronic myeloid leukemia, Hb falls from llg% to 4g% in a sho span of time, and splenomegaly occurs. The cause could be - \nSelect and explain. \nA. Accelerated phase, B. CML in blast crisis, C. Ineffective erythropoiesis, D. Myelofibrosis', 'role': 'user'}, {'content': 'Answer: A \nExplanation: <p>Accelerated phase of CML is defined as increasing degree of anemia ,blast count in blood or marrow between 10-20% ,marrow basophils 20% or more ,platelet ciunt falling below 1,00,000/microlitre.An accelerated phasecof CML is characterised by progressively rising leucocytosis associated with thrombocytosis or thrombocytopenia & splenomegaly. </p><p>Reference :Harsh mohan textbook of pathology sixth edition pg no 358</p>', 'role': 'assistant'}]