This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Medicine
[{'content': 'Two litres of normal saline in 4 hours will stimulate secretion of- \nSelect and explain. \nA. Atrial natriuretic peptide, B. IL-2, C. TNF - alpha, D. Prostaglandins', 'role': 'user'}, {'content': 'Answer: A \nExplanation: hyperosmolality occurs and blood volume increase causing atrial distention stimulating atrial natriuretic peptide ( Harrison 17 pg 1760)', 'role': 'assistant'}]