This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Rheumatic Heart Disease, Subject name: Pediatrics
[{'content': 'Which of the follow ing is not a major criteria for rheumatic fever- \nSelect and explain. \nA. Carditis, B. Arthralgia, C. Erythema marginatum, D. Subcutaneous nodule', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., Arthralgia Guidelines for the Diagnosis of Initial Attack of Rheumatic Fever (Jones Criteria, Updated 1992)Major manfestationsMinor manfestationsSupporting evidence of antecedent group A Streptococal infectionCarditisClinical features:Positive throat culture or rapid streptococcal antigen testPolyarthritisArthralgia FeverElevated or increasing streptococcal antibody titerErythema marginatumLaboratory features: Subcutaneous nodulesElevated acute phase reactants : Erythrocyte sedimentation rate C-reactive protein Prolonged PR interval Chorea o From Jones criteria, updated 1992. JAMA 1992;268:2069-2073. Copyright American Medical Association.o The presence of 2 major or of 1 major and 2 minor manifestations indicates a high probability of acute rheumatic fever if supported by evidence of preceding group A streptococcal infection.", 'role': 'assistant'}]