This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
[{'content': "Splenic macrophages in Gaucher's disease differ from those in ceroid histiocytosis by staining positive for for \nSelect and explain. \nA. Lipids, B. Phospholipids, C. Acid fast stain, D. Iron", 'role': 'user'}, {'content': 'Answer: A \nExplanation: Gaucher disease results from mutation in the gene that encodes glucocerebrosidase. This deficit leads to an accumulation of glucocerebroside, an intermediate in glycolipid metabolism, in the mononuclear phagocytic cells and their transformation into so-called Gaucher cells. Gaucher cells contain abundant lipid-laden granular cytoplasm. (Robbins Basic Pathology, 9 th edition. page : 231)', 'role': 'assistant'}]