This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Medicine
[{'content': 'All are true regarding Hodgkin&;s lymphoma, except - \nSelect and explain. \nA. CNS is the commonest site of involvement, B. Characteristic cell is a Reed Sternberg cell (AI2K), C. Mediastinal involvement is common in nodularsclerosis type, D. Eosinophils, plasma cells and neutrophils increase', 'role': 'user'}, {'content': 'Answer: A \nExplanation: <p>Hodgkin lymphoma arise in a single lymph node or a chain of lymph nodes & typically spread in a stepwise fashion to anatomically contiguous nodes. Extranodal involvement is uncommon.</p><p>Reference : Robbins basic pathology 9th edition pg no 440</p>', 'role': 'assistant'}]