This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
[{'content': 'Basement membrane degeneration is mediated by: \nSelect and explain. \nA. Metalloproteinases, B. Oxidases, C. Elastases, D. Hydroxylases', 'role': 'user'}, {'content': 'Answer: A \nExplanation: A i.e. MetalloproteinasesZinc dependent matrix metalloproteinases (MMP) degrade collagen and other extracellular matrix proteins (including that of basement membrane)Q.', 'role': 'assistant'}]