This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'IgG is normal or slightly reduced in A/E - \nSelect and explain. \nA. Wiskott aldrich syndrome, B. Selective IgA deficiency, C. Di George syndrome, D. Common variable deficiency', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Wiskott-Aldrich syndrome o In Wiskott - Aldrich syndrome IgG levels are normal or elevated (not reduced). o In selective IgA deficiency IgG2 and IgG4 may be reduced. o In Digeorge syndrome serum immunoglobulin concentration are frequently normal but antibody responses, paicularly of IgG and IgA isotopes, are usually impaired. o In common variable immunodeficiency IgG level is decreased.", 'role': 'assistant'}]