This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti Cholinergic, Subject name: Pharmacology
[{'content': 'Drug of choice for belladoma poisoning - \nSelect and explain. \nA. Neostigmine, B. Physostigmine, C. Tacrine, D. Hyoscine', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., Physostigmine o Physostigmine penetrates blood-brain barrier and antagonizes both central and peripheral actions of anticholinergics in acute anticholinergic poisoning (belladonna poisoning).About other optionso Neostigmine does not cross blood brain barrier. Thus it is ineffective for central anticholinergic actionso Tacrine is used for chronic central anti-cholinergic syndrome (Alzhiemer's disease).", 'role': 'assistant'}]