This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Dental
[{'content': 'Useful markers of epithelial differentiation are \nSelect and explain. \nA. Fillagrin, B. Loricin, C. Both, D. None', 'role': 'user'}, {'content': "Answer: C \nExplanation: The protein making the bulk of keratohyalin granules is fillagrin. Also sulfur-rich protein loricin is present. \xa0Fillagrin and loricin are useful markers of epithelial differentiation. Involucrin contributes to the 'Cornified cell envelope' in the cell membrane of keratohyalin cells.", 'role': 'assistant'}]