This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: NEET 2018, Subject name: Anatomy
[{'content': 'What constitutes malpighian layer \nSelect and explain. \nA. Stratum lucidum, B. Stratum spinosum, C. Stratum granulosum, D. Stratum spinosum and basale', 'role': 'user'}, {'content': "Answer: D \nExplanation: Stratum basale + stratum spinosum = malphigian layer Layers of the epidermis : Stratum basale: Deepest layer. Single layer of columnar cells on the basal lamina aka germinal layer - produces Keratinocytes Stratum spinosum: Several layers of polygonal keratinocytes attached to one another by desmosomes (responsibly for 'Spiny' appearance) Stratum granulosum: Few layers of flattened cells that are characterised by deep staining granules of keratohyalin in their cytoplasm. Stratum lucidum: This layer appears homogenous with indistinct cell boundaries & tracts of flattened nuclei. Present in areas of thick skin. Stratum corneum: Acellular layer made up of flattened scale like elements containing keratin filaments embedded in protein.", 'role': 'assistant'}]