This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pathology
[{'content': 'The probable interval between throat infection and onset of rheumatic fever is \nSelect and explain. \nA. 2-4 hours, B. 2-4 days, C. 2-4 weeks, D. 2-4 months', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Rheumatic fever is an acute, immunologically mediated, multisystem inflammatory disease that occurs after group A b-hemolytic streptococcal infections (usually pharyngitis, but also rarely with infections at other sites such as skin). Acute rheumatic fever occurs most often in children; the principal clinical manifestation is carditis. Neveheless, about 20% of first attacks occur in adults, with ahritis being the predominant feature. Symptoms in all age groups typically begin 2 to 3 weeks after streptococcal infection, and are heralded by fever and migratory polyahritis. (Robbins basic pathology,9th edition.pg no.391)', 'role': 'assistant'}]