This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Medicine
[{'content': 'KIM-1 is a novel biomarker for \nSelect and explain. \nA. Acute kidney injury, B. Chronic kidney injury, C. Renal cellular carcinoma, D. Renal metastasis', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Kidney injury molecule-1 (KIM-1) is a type 1 transmembrane protein that is abundantly expressed in proximal tubular cells injured by ischemia or nephrotoxins such as cisplatin. KIM-1 can be detected sholy after ischemic or nephrotoxic injury in the urine and, therefore, may be an easily tested biomarker in the clinical setting. Neutrophil gelatinase-associated lipocalin (NGAL, also known as lipocalin- 2 or siderocalin) is another novel biomarker of AKI. Other candidate biomarkers of AKI include interleukin (IL) 18, a proinflammatory cytokine of the IL-1 superfamily Ref: Harrison 19e 1808', 'role': 'assistant'}]