This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of protein and amino acid, Subject name: Biochemistry
[{'content': 'Following clinical manifestation is a feature of \nSelect and explain. \nA. Hyperammonemia type 1, B. Hyperammonemia type 2, C. Argininosuccinic aciduria, D. Argininemia', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Image showing Trichorrhexis nodosa. Argininosuccinic aciduria, accompanied by elevated levels of argininosuccinate in blood, cerebrospinal fluid, and urine, is associated with friable, tufted hair (trichorrhexis nodosa). It is due to the deficiency of the enzyme argininosuccinate lyase. Reference: Harpers illustrated biochemistry 30th edition', 'role': 'assistant'}]