This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: parasitology, Subject name: Microbiology
[{'content': 'Drug of choice to treat Toxoplasmosis in first-trimester of pregnancy is \nSelect and explain. \nA. Spiramycin, B. Pyrimethamine-Sulphonamide, C. Atovaquone, D. Ivermectin', 'role': 'user'}, {'content': "Answer: A \nExplanation: Compound Drug class Route Mechanism of action Clinical use Comment Spiramycin Macrolide Oral Blocks proteinsynthesis Toxoplasmosis Used to treat pregnantwomen Ref : Paniker's textbook of Medical Parasitology Pgno : 241,242", 'role': 'assistant'}]