This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: miscellaneous, Subject name: Biochemistry
[{'content': 'Home to bilirubin conversion is carried out by \nSelect and explain. \nA. Heme oxygenase, B. Heme reductase, C. Heme isomerase, D. Heme hydrolase', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Within the macrophage, heme derived from haemoglobin is broken down by heme oxygenase, conveing it to biliverdin Carbon monoxide and iron arereleased as by-productsReference: Harper biochemistry 30th edition page no 672', 'role': 'assistant'}]