This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Orthopaedics
[{'content': 'Which of the following statements about changes in articular cartilage with aging is not true - \nSelect and explain. \nA. Total proteoglycan content is decreased, B. Synthesis of proteoglycans is decreased, C. Enzymatic degradation of proteoglycans is increased, D. Total water content of cartilage is decreased', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Normal aging Vs osteoarthritic pathology of articular cartilage\n\nNormally, many morphological changes take place as the articular cartilage undergoes aging.\nThough aging is the most important risk factor for developing OA, many of the changes that occur with normal aging of articular cartilage are different from those seen in osteoarthritis.', 'role': 'assistant'}]