This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Bleeding Disorders, Subject name: Pathology
[{'content': 'FFP not used in - \nSelect and explain. \nA. TTP, B. Factor XII deficiency, C. Vitamin K deficiency, D. Antithrombin III deficiency', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., Factor XII deficiency Fresh frozen plasma (FFP)o FFP is defined as the fluid portion of human blood that has been centrifuged, separated, and frozen solid at -18degc within 6 hours.o FFP contains stable coagulation factors and plasma proteins : -(i) Fibrinogen(ii) Antithrombin(iii) Albumin & Immunoglobulin(iv) Protein C, S.(v) Factor II, V, VII, IX, X, XIo Indications for the use >>f FFP are : -Deficiencies of factor II, V, VII, IX, X and XI when specific component therapy is neither available nor appropriate.Emergency reversal of warfarin effect.In vit K deficiency as replacement for Vit K dependent factors (II, VII, IX, X)Antitbrombin III deficiencyAfter massive blood transfusion.In immunodeficiency as a source of immunoglobulinTTPNote : Options 'c', is partially correct, FFP can be used for deficiency of factor IX but not for factor VIII.", 'role': 'assistant'}]