This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
[{'content': 'Which of the following hormones are secreted by Pheochromocytoma to cause its clinical manifestations? \nSelect and explain. \nA. Epinephrine, B. Norepinephrine, C. Dopamine, D. All', 'role': 'user'}, {'content': "Answer: D \nExplanation: Hypeension in pheochromocytoma results from the direct effect of high circulating levels of catecholamines, primarily noradrenaline, adrenaline, and dopamine. Some tumors produce the catecholamine precursor L-dopa. Pheochromocytomas also secrete numerous other peptide hormones, among which are renin, VIP, neuropeptide, Y, somatostatin, and ET-1. These substances are responsible for many of the nonhypeensive symptoms seen in patients with pheochromocytoma, including flushing, sweating, and diarrhoea. Ref: Pediatric Nephrology, 5e By Ellis D. Avner, William E. Harmon, Ellis D. Avner William Harmon Patrick Niaudet, 2003, Page 1167; Harrison's Internal Medicine > Chapter 337. Pheochromocytoma", 'role': 'assistant'}]