This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Psychiatry
[{'content': 'Treatment of choice in severe depression is - \nSelect and explain. \nA. Fluoxetine, B. Alprazolam, C. ECT, D. None', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Make it very clear in your mind that the initial treatment of choice for severe depression is antidepressant medications.\nECT is the treatment of choice when severe depression is associated with a suicidal tendency or when severe depression is associated with psychotic features or when severe depression is refractory to antidepressants.', 'role': 'assistant'}]