This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Fluid and electrolytes, Subject name: Medicine
[{'content': 'Effects of hypokalemia- \nSelect and explain. \nA. Acidosis, B. Arrhythmia, C. Ileus of intestine, D. Polyuria', 'role': 'user'}, {'content': 'Answer: A \nExplanation: * The functional effects of hypokalemia on the kidney can include Na+-Cl- and HCO3- retention, polyuria, phosphaturia, hypocitraturia, and an activation of renal ammoniagenesis. Bicarbonate retention and other acid-base effects of hypokalemia can contribute to the generation of metabolic alkalosis * Hypokalemia is a major risk factor for both ventricular and atrial arrhythmias * Hypokalemia also results in hyperpolarization of skeletal muscle ,thus impairing the capacity to depolarize and contract; weakness and even paralysis may ensue. It also causes a skeletal myopathy and predisposes to rhabdomyolysis. Finally, the paralytic effects of hypokalemia on intestinal smooth muscle may cause intestinal ileus. (REF : harrisons principles of internal medicine, 19E, pg 308)', 'role': 'assistant'}]