This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Inflammation & Repair, Subject name: Pathology
[{'content': 'Amino acid which is usehil in Neutrophil extracellular traps (NETs) as to causes lysis of chromatin is? \nSelect and explain. \nA. Arginine, B. Alanine, C. Phenyl alanine, D. Valine', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. (a) Arginine(Ref: R 9th/pg 81)NETs contain a framework of nuclear chromatin with embedded granule proteins, such as antimicrobial peptides and enzymes. The nuclear chromatin in the NETs, includes histones and associated DNA. Histone modification by peptidylarginine deiminase 4 (PAD4) is necessary for NET release.', 'role': 'assistant'}]