This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Anaesthesia
[{'content': 'Methemoglobinemia is associated with: \nSelect and explain. \nA. Aicaine, B. Prilocaine, C. Bupivacaine, D. Mepivacaine', 'role': 'user'}, {'content': "Answer: B \nExplanation: A unique systemic side effect associated with a specific local anesthetic is the development of methemoglobinemia after the administration of large doses of prilocaine. In general, 600-mg doses are required for the development of clinically significant levels of methemoglobinemia in adults. Ref: Miller's anesthesia-7th ed, Chapter 30.", 'role': 'assistant'}]