This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nuclear medicine, Subject name: Radiology
[{'content': 'All the following show hot spot on Bone Scan except? \nSelect and explain. \nA. Multiple Myeloma, B. Fibrous Dysplasia, C. Pagets Disease, D. Osteomyelitis', 'role': 'user'}, {'content': "Answer: A \nExplanation: Bone scan: Done with: Tc99m-MDP (Methylene diphosphonate) Tc99m Medronate Hot uptake on bone scan indicates osteoblastic activity Cold uptake on bone scan indicates osteoclastic activity Hot uptake of bone scan seen with: Osteoblastic metastasis/ prostatic metastasis Paget's disease Fibrous dysplasia Osteoahritis Osteomyelitis (3 phase bone scan) Cold uptake of bone scan is seen in: Multiple myeloma (not preferred for bone scan) Focal coical defects", 'role': 'assistant'}]