This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Skin
[{'content': 'Regarding leprosy true is \nSelect and explain. \nA. Lives in parts of body where temperature is <37 degrees, B. Can grow in cell free culture media, C. Can be seen in biopsies in tuberculoid leprosy, D. Sensitive to INH and Rifampicin', 'role': 'user'}, {'content': 'Answer: D \nExplanation: (D) Sensitive to INH and Rifampicin # LEPROSY, is a nonfatal ] chronic infectious disease caused by Mycobacterium leprae: the clinical manifestations of which are largely confined to the skinL peripheral nervous system 3 upper respiratory tract, eyes, and testis.> M. leprae remains one of the few bacterial species that still has not been cultivated on artificial medium or tissue culture.The multiplication of M. leprae in mouse footpads.> AFB are generally absent or few in number in tuberculoid leprosy.> WHO recommends that pauci bacillary adults be treated with 100 mg of dapsone daily and 600 mg of rifampin monthly (supervised) for 6 months.> Multibacillary adults should be treated with 100 mg of dapsone plus 50 mg of clofazimine daily (unsupervised) and with 600 mg of rifampin plus 300 mg of clofazimine monthly (supervised).> WHO recommended that lepromatous patients be treated for 2 years or until smears became negative (generally in -5 years); subsequently the acceptable course was reduced to 1 year.', 'role': 'assistant'}]