This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Which of the following are intracellular events occurring in fibroblast during synthesis of collagen- \nSelect and explain. \nA. Hydrolysis of procollagen to collagen, B. Glycosylation of proline, C. Formation of triple helix, D. Formation of covalent cross link b/w fibrils', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Formation of triple helix (of pre-a-chains) takes place intracellularly in RER.\nFormation of a cross-link between fibrils (i.e. self-assembly of tropocollagen monomers into mature collagen fiber) occurs extracellularly after secretion from fibroblasts.\nGlycosylation also occurs intracellularly, but its glycosylation of hydroxylysine (not of proline).', 'role': 'assistant'}]