This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Integrated QBank, Subject name: Anatomy
[{'content': 'A 70-year-old male presented to the OPD with progressive jaundice for 6 weeks, fever, pruritis along with abdominal pain and significant weight loss. Lab findings reveal, Total S. bilirubin - 22 mg/dL Minimally elevated SGOT/SGPT Increased alkaline phosphatase CT abdomen was done along with ERCP. What is the most common site of this pathology: - \nSelect and explain. \nA. Intrahepatic bile duct, B. Distal CBD, C. Proximal CBD, D. Hilum', 'role': 'user'}, {'content': 'Answer: D \nExplanation: This is a case of Cholangiocarcinoma. CT scan shows dilated intrahepatic biliary ducts. Cholangiocarcinoma is a malignant tumor arising from cholangiocytes in the biliary tree. It tends to have a poor prognosis and high morbidity. Most common presentation - Painless jaundice > Pruritis > Abdominal pain, weight loss and fever. Most common site - Hilum > Distal CBD > Intrahepatic bile ducts.', 'role': 'assistant'}]