This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cellular Pathology, Subject name: Pathology
[{'content': 'Cytokine causing fever - \nSelect and explain. \nA. IL-6, B. IFN-y, C. IL-18, D. EL-4', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., IL-6 Pyrogeneso Pyrogenes are substances that cause fever,o Pyrogens may be exogenous or endogenousExogenous - Bacterial toxinsEndogenous - IL-1, TNF-a, IL-6, Interferons, Ciliory's neurotropic factoro These pyrogenes increase the level of PGE2 in the hypothalamus that elevates the thermoregulatory set point and causes fever.", 'role': 'assistant'}]