This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
[{'content': 'Graft rejection is - \nSelect and explain. \nA. Cell mediated, B. Humoral, C. Both, D. None', 'role': 'user'}, {'content': 'Answer: C \nExplanation: harshmohan textbook of pathology 7th edition. *rejection of allograft involves both cell mediated and humoral immunity .cell mediated reaction is mainly responsible for graft rejection and are mediated by T cells.in addition to cell mediated reaction a role for humoral antibodies in ceain rejection reaction has been suggested. These included pre formed circulating antibodies due to pre sensitization of the recipient before transplantation.', 'role': 'assistant'}]