This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Other topics and Adverse effects, Subject name: Pharmacology
[{'content': 'If amphotericin B is administered, the patient should be premedicated with: \nSelect and explain. \nA. Diphenhydramine, B. Ibuprofen, C. Prednisone, D. Any of the above', 'role': 'user'}, {'content': 'Answer: D \nExplanation: (Ref: KDT 6/e p783) To prevent the acute reation due to amphotericin B, patient should be premedicated with Hi antihistaminics like diphenhydramine NSAIDs like ibuprofen Steroids like prednisone', 'role': 'assistant'}]