This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Rosenthal fibres are - \nSelect and explain. \nA. Intranuclear inclusions, B. Intracytoplasmic inclusions, C. Present extracellularly, D. Part of cell membrane', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Rosenthal fibers are beaded, elongated, or corkscrew-shaped intracytoplasmic inclusions measuring approximately 10-40 cm in diameter.\nThey are identified occasionally in astrocytes associated with intense fibrillary gliosis.\nThese have been described in reactive tissue (such as the highly gliotic tissue surrounding cysts and vascular malformations), in neoplasms (such as juvenile pilocytic astrocytomas), and Alexander disease.', 'role': 'assistant'}]