This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Incretin like function is seen in ? \nSelect and explain. \nA. Exenatide, B. Miglital, C. Poiglitazone, D. Repaglinide', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Exenatide Exenatide is a synthetic glucagon-like peptide - 1 (GLP-1) analogue. GLP-1 is an impoant incretin that is released from gut in response to oral glucose. But GLP-1 can not be used clinically as it is degraded rapidly by enzyme dipeptidly peptidase - (DPP-4). Exenatide is resistant to DPP-4. It acts similar to GLP-1 - Enhancement of postprandial insulin release, suppression of glucagon release and appetite as well as slowing of gastric emptying. It is given by subcutaneous route & used in type 2 DM Nausea is most impoant side effect.", 'role': 'assistant'}]