This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: NEET Jan 2020, Subject name: Pathology
[{'content': 'A middle-aged male presented with history of fatigue and tiredness. On investigating, he had a hemoglobin of 8g/dL and MCV of 110 fl with the peripheral smear showing macrocytes and hypersegmented neutrophils. Which of the following is the most likely cause of the findings in this patient? \nSelect and explain. \nA. Ancylostoma duodenale infestation, B. Chronic alcoholism, C. Chronic renal failure, D. Colon cancer', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ancylostoma duodenale (hookworm) infestation and colon cancer can be associated with chronic blood loss leading to iron deficiency (microcytic hypochromic anemia). Chronic renal failure can lead to anemia of chronic inflammation which usually presents with normocytic normochromic anemia. Chronic alcoholism can be associated with folic acid deficiency which causes megaloblastic anemia (macrocytosis, elevated MCV, hypersegmented neutrophils).', 'role': 'assistant'}]