This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Glomerular Diseases, Subject name: Medicine
[{'content': 'First manifestation of Alport syndrome is : \nSelect and explain. \nA. Microscopic haematuria, B. Proteinuria, C. Oliguria, D. Sensorineural deafness', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' Microscopic hematuria (Ref Harrison, 17/e p 2469, 16/e, p 2331 (15/e, p 1595)).The first symptom of Alport's syndrome is not mentioned anywhere.But in Harrison it is written that patients with Alport's syndrome usually presents with microscopic hematuria, proteinuria (nephrotic range in 30%) and progressive renal insufficiency.So the first symptom of Alport's syndrome can be taken as microscopic hematuria.Common extra renal manifestations include:Sensorineural hearing loss* (60%).Bilateral anterior lenticonus SC (15-30%)Recurrent corneal erosions*.", 'role': 'assistant'}]