This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pathology
[{'content': 'GNAS mutation is associated with malignancy of \nSelect and explain. \nA. Lactotrophs, B. Somatotrophs, C. Thyrotrophs, D. Coicotrophs', 'role': 'user'}, {'content': 'Answer: B \nExplanation: GNAS encodes for alpha subunit of stimulatory G-protein , Gsalpha . Oncogenic activation of GNAS constitutively activates Gsalpha leading to Growth hormone(GH) adenomas. Ref: Robbins and cotrans 9e Pg 1076', 'role': 'assistant'}]