This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General anatomy, Subject name: Anatomy
[{'content': 'Drug has 40% absorption and hepatic extraction ratio of 0.6.what is bioavailabilit of the drug \nSelect and explain. \nA. 16%, B. 20%, C. 24%, D. 28%', 'role': 'user'}, {'content': 'Answer: A \nExplanation: (Ref Goodman and Gilman 12th/20) If we administer 100 molecules of the drug. Amount absorbed = 40 molecules (40% absorption) Amount removed by liver - 40 x 0.6 (Hepatic extraction ratio) = 24 molecules Drug available to produce action = 40-24 = 16 molecules So, Bioavailability = 16 percent', 'role': 'assistant'}]