This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': "The subtype of Hodgkin's disease, which is histogentically distinct from all the other subtypes, is - \nSelect and explain. \nA. Lymphocyte predominant, B. Nodular sclerosis, C. Mixed cellularity, D. Lymphocyte depleted", 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans is 'a' i.e., Lymphocyte predominance Hodgkins lymphoma can be divided into two groups. Classical hodgkin lymphoma o This group includes (i) Nodular sclerosis (iii) Lymphocyte-rich (ii) Mixed cellularity (iv) Lymphocyte-depletion o The Reed-sternberg cells have similar immunophenotype, i.e., express CD 15 and CD 30. 2. Lymphocytic predominance Hodgkin lymphoma o The Reedsternberg cells express CD 20 marker, characteristic B-cell immunotype.", 'role': 'assistant'}]