This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
[{'content': 'All are true regarding interleukin-1 except ? \nSelect and explain. \nA. Primary source is monocyte-macrophage system, B. Endogenous pyrogens, C. Inhibit IL-2 production by T-cells, D. All are true', 'role': 'user'}, {'content': "Answer: C \nExplanation: Ans. is 'c' i.e., Inhibit IL-2 production by T-cells Interleukin -1 Also known as leucocyte activating factor (LAF) or B cell activating factor (BAF). Principally secreted by macrophages and monocytes; and epithelial cells. Other sources are B lymphocytes, fibroblasts and endothelial cells. Immunological effects- Activation of T cells for the production of IL - 2. B cell proliferation and antibody synthesis Neutrophil chemotaxis and increased PMN release from bone marrow. Increases body temperature (impoant endogenous pyrogen). Bone marrow cell proliferation Induction of acute phase protein.", 'role': 'assistant'}]