This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': 'Conjugated hyperbilirubinemia \nSelect and explain. \nA. Dubin johnson syndrome, B. Criggler naj jar syndrome, C. Breast milk jandice, D. Gilbe syndrome', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Dubin johnson syndrome Breast milk jaundice - Decrease bilirubin uptake across hepathocyte membrane. Entero-hepatic recirculation. Leads to indirect hyperbilirubinemia. Crigler naj jar & Gilbe syndrome (deficiency of glucuronyl transferase) <Type I - Complete deficiency Type II - Paial deficiency Decrease conjugation leads to Indirect hyperbilirubinemia. Defect in hepatocyte secretion of conjugated bilirubin. Leads to direct hyperbilirubinemia", 'role': 'assistant'}]