This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hematology and CVS, Subject name: Pharmacology
[{'content': 'Drugs that have been found to be useful in compensated hea failure include all of the following except: \nSelect and explain. \nA. Na+ K+ ATPase inhibitors, B. Aldosterone antagonists, C. BNP analogue, D. Beta receptor antagonists', 'role': 'user'}, {'content': 'Answer: C \nExplanation: BNP analogue (Nesiritide) are used in acute cardiac failure not used in chronic therapy. Compensated hea failure (Chronic CHF): Management: Digitalis (Na+ - K+ ATPase inhibitor) - Inhibit Na+/K+ ATPase--> positive inotropic action. It does not acts as chronotropic agent so no increase in workload on hea and useful in chronic conditions. Aldosterone antagonist: Decreases morbidity/moality. Used to prevent cardiac remodelling along with ACE inhibitors and ARBs. b blockers: These drugs can precipitate acute decompensation of cardiac function but are used in chronic CHF as these decrease moality by reversing LVH.', 'role': 'assistant'}]