This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
[{'content': 'Paul Bunnell test is for \nSelect and explain. \nA. Malta fever, B. Typhus fever, C. Enteric fever, D. Infectious mononucleosis', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Laboratory diagnosis of IMN\n1. Heterophile antibodies test\n\n\xa0The standard diagnostic procedure in children and young adults is heterophile antibodies test - Paul – Bunnell Test\n\xa0A titre of 40 fold or greater is diagnostic of acute EBV infection in a patient who has symptoms compatible with infectious mononucleosis,\n\xa0The test usually remains positive for 3 months.\n\xa0The test is usually negative in children < 5 years, in elderly or in patients with symptoms not typical of infectious mononucleosis.\n\xa0Monospot test for heterophile antibodies is more sensitive than the classical heterophile test.\n\n2. EBV specific antibody test\n\n\xa0Used in patients who lack heterophile antibodies (children < 5 years) and for patients with atypical presentation.\n\nanti-viral capsid antigen (anti-VCA)→most common anti-EBV nuclear antigen (anti-EBNA) anti - early antigen (anti - EA)', 'role': 'assistant'}]