This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: recent papers  obst, Subject name: Gynaecology & Obstetrics
[{'content': 'Which of the following statements is true about toxoplasmosis? \nSelect and explain. \nA. Maximum transmission and damage in 1st trimester, B. Maximum transmission in 1st trimester and Maximum damage in 3rd trimester, C. Maximum damage in 1st trimester and maximum transmission in 3rd trimester, D. Maximum transmission and damage in 3rd trimester', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Toxoplasmosis causes maximal damage in 1st trimester but the risk of transmission increases and risk of damage decreases as pregnancy progress fuher. Clinical features of affected neonates: Low bih weight Hepatosplenomegaly Jaundice Anemia Neurological disease with intracranial calcifications Hydrocephaly or microcephaly Tetrad of toxoplasmosis-Chorioretinitis, intracranial calcifications, and hydrocephalus often accompanied by convulsions. Ref: Williams Obstetrics 25th edition Pgno: 1225', 'role': 'assistant'}]