This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pathology
[{'content': 'Which is not major Criteria rheumatic fever? \nSelect and explain. \nA. Carditis, B. Subcutaneous nodules, C. Increased ASLO, D. Ahritis', 'role': 'user'}, {'content': 'Answer: C \nExplanation: The diagnosis of acute rheumatic fever is made based on serologic evidence of previous streptococcal infection in conjunction with two or more of the so-called Jones criteria: (1) carditis; (2) migratory polyahritis of large joints; (3) subcutaneous nodules; (4) erythema marginatum skin rashes; and (5) Sydenham chorea, a neurologic disorder characterized by involuntary purposeless, rapid movements (also called St. Vitus dance). Minor criteria such as fever, ahralgias, ECG changes, or elevated acute phase reactants also can help suppo the diagnosis. (Robbins Basic pathology,9th edition.pg no.392)', 'role': 'assistant'}]