This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'The enzyme deficient in Galactosemia is: \nSelect and explain. \nA. Hexoseaminidase B, B. Hexosaminidase A, C. Galactose 1 phosphate uridyltransferase, D. Glucocerebrosidase', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ref. Textbook of Biochemistry for Medical Students. Page. 183\nGalactosemia is an autosomal recessive trait that results from a defective gene encoding either galactokinase or galactose 1-P uridyltransferase. \n\nThere are\u2028over 100 heritable mutations that can cause galactosemia, and the incidence is approximately 1 in 60,000 births.\nGalactose will be present in elevated amounts in the blood and urine and can result in decreased glucose synthesis and hypoglycemia.\nGalactosemia symptoms often begin around day 3 in a newborn and include the hallmark cataracts.\nJaundice and hyperbilirubinemia do not resolve if the infant is treated with phototherapy\nSevere bacterial infections ( E.coli sepsis) are common\u2028in untreated galactosemic infants. Failure to thrive, lethargy, hypotonia, and mental retardation are other common and apparent features', 'role': 'assistant'}]