This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Glycolysis, Subject name: Biochemistry
[{'content': "ATP's formed in anaerobic glycolysis of glucose are: \nSelect and explain. \nA. 2, B. 8, C. 10, D. 15", 'role': 'user'}, {'content': "Answer: A \nExplanation: ATP's formed in anaerobic glycolysis are 2: NADH is used by Lactate Dehydrogenase under anaerobic conditions (Step 11). So 5 ATPs which are derived from NADH in Aerobic condition, are not obtained in Anaerobic conditions. So energetics is : 2 Substrate Level Phosphorylations - + 4 ATPs Hexokinase and PFK-1 uses ATPs - - 2 ATPs Total 4-2 - 2 ATPs So, only 2 ATPs are obtained in case of Anaerobic Glycolysis ADDITIONAL EDGE: ATP's formed in aerobic glycolysis are 7. Energetics of Aerobic Glycolysis: 2 NADH + 5 ATPs (from ETC) 2 Substrate level Phosphorylations - + 4 ATPs Hexokinase and PFK-1 uses ATPs - - 2 ATPs Total - 9-2 = 7 ATPs So, 7 ATPs are obtained in case of Aerobic Glycolysis.", 'role': 'assistant'}]