This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.V.S, Subject name: Medicine
[{'content': 'Risk factors for coronary aery disease \nSelect and explain. \nA. High HDL, B. Low HDL, C. Increased homocysteine levels, D. Decreased fibrinogen levels', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ref Harrison 19 th ed pg 1579 The major risk factors for atherosclerosis (high levels of plasma low-density lipoprotein , low plasma high-density lipoprotein , cigarette smoking, hypeension, and diabetes mellitus disturb the normal functions of the vascular endothelium.', 'role': 'assistant'}]