This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'Specific test for gout is: \nSelect and explain. \nA. Raised serum uric acid level, B. Raised uric acid in synol fluid of joint, C. Raised urea level, D. Raised urease enzyme level', 'role': 'user'}, {'content': 'Answer: B \nExplanation: B i.e. Raised uric acid in synol fluid of joint - Gout is a metabolic disorder of purine catabolismQ, and characterized by high level of uric acid in the blood . Uric acid is end product of purine catabolismQ - Pyrimidine nucleotide unlike purine rings can be opened & degraded to highly water soluble structure like, p- alanine, /3? amino isobutyrate, NH3 & CO2. Excess meabolism of pyrimidine therefore does not give rise to clinical manifestationQ Human catabolizes purine (Adenine & Guamine) to uric acid, which is relatively insoluble acid.', 'role': 'assistant'}]