This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
[{'content': 'A substance which binds to the enzyme other than catalytic site is - \nSelect and explain. \nA. Competitive inhibitor, B. None of the above, C. Reversible inhibitor, D. Non-competitive inhibitor', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Non-competitive inhibitor\no In this type of inhibition no competition occurs between substrate and inhibitor.\no Inhibitor is structurally different from substrate and binds to enzyme at a site other than the substrate binding (catalytic) site.\nOccupancy of this site by the inhibitor alters the shape of the enzyme such that its catalytic activity is reduced or lost.\no The substrate is still able to bind the enzyme, but the enzyme cannot catalyze the reaction when inhibitor is bound.\no Thus, the non-competitive inhibitor does not block the active site of enzyme, but behaves as though it were removing active enzyme from the solution.\no Evidently, unlike competitive inhibition, increasing the substrate concentration does not reverse the inhibition,', 'role': 'assistant'}]