This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of carbohydrate, Subject name: Biochemistry
[{'content': 'Phosphorylation of phosphofructokinase and fructose-1,6-bisphosphate by fructose-2,6-bisphosphate regulation is seen in \nSelect and explain. \nA. Brain, B. Liver, C. Adrenal Coex, D. RBC', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Fructose-2,6-bisphosphate (F-2,6-BP) increases the activity of phosphofructokinaseF-2,6-BP is formed from fructose-6-phosphate by the action of an enzyme called PFK-2. (It is different from the PFK1)Fructose-2,6bisphosphate is hydrolysed to fructose-6phosphate by fructose-2,6-BisphosphataseThe activities of both the enzymes (PFK2 and fructose-2,6-bisphosphatase) are reciprocally regulated.When glucose supply is in plenty, PFK-2 is dephosphorylated and activated; so F2,6-BP concentration increases; this, in turn, activates PFK. Thus glycolysis is ored Ref: DM Vasudevan, 6th edition, page no: 98-99', 'role': 'assistant'}]