This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Schizophrenia Spectrum and Other Psychotic Disorders, Subject name: Psychiatry
[{'content': 'The least likely good prognostic factor in a patient with Schizophrenia is? \nSelect and explain. \nA. Premorbid personality issues, B. Acute onset, C. Female gender, D. History of mood disorder in the family', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Premorbid personality issues is a bad prognostic factor for schizophrenia. Schizophrenia Good Prognosis Bad Prognosis Acute onset (<2 weeks) Insidious onset Advanced age at onset (>35 year) Early onset <20 year) Catatonic subtype (Paranoid subtype has an intermediate prognosis) Simple, disorganized, hebephrenic Female Sex Male Sex Prominent Positive Symptom Prominent Negative symptom Presence of affective symptom Absence of affective symptoms Family H/O mood disorder Family h/o Schizophrenia Good premorbid functioning and personality traits Poor premorbid functioning and personality traits', 'role': 'assistant'}]