This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Trisomy 21 is associated with: September 2008 \nSelect and explain. \nA. ALL, B. AML, C. Both of the above, D. None of the above', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans. C: Both of the aboveChildren with trisomy 21 have a 10-20 fold increased risk of developing acute leukemia.Both AML and ALL can occur.AML, most commonly, is acute megakaryoblastic leukemia.', 'role': 'assistant'}]