This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nephritic & Nephrotic Syndrome, Subject name: Pediatrics
[{'content': 'IgA nephropathy is characterised by:- \nSelect and explain. \nA. Hematuria occur after skin infection, B. Severe Hypeension, C. Normal serum levels of C3, D. Serum IgA levels have a diagnostic value', 'role': 'user'}, {'content': 'Answer: C \nExplanation: IgA nephroapthy is also known as Berger nephropathy Gross Hematuria in IgA nephropathy occurs within 1-2 days of onset of an upper respiratory or GI infection (skin infection leads to poststreptococcal glomerulonephritis (PSGN)and not IgA nephropathy). Mild to moderate hypeension can be seen May be associated with loin pain Normal serum levels of C3 in IgA nephropathy help to distinguish this disorder from poststreptococcal glomerulonephritis (PSGN) where serum C3 levels are low. Serum IgA levels have no diagnostic value in IgA nephropathy because they are elevated in only 15% of pediatric patients. Note: Most Common GN overall - IgA nephropathy/Berger disease (M.C Clinical Feature -Recurrent gross hematuria)', 'role': 'assistant'}]