This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'COX pathway is inhibited by : \nSelect and explain. \nA. Aspirin, B. Indomethacin, C. Diclofenac, D. All of these', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Aspirin inhibits COX irreversibly by acetylating one\xa0of its serine residues; return of COX activity depends\xa0on synthesis of fresh enzyme. Other NSAIDS like indomethacin, diclofenac etc are competitive and reversible inhibitors of COX, return of activity depends\xa0on their dissociation from the enzyme which in\xa0turn\xa0is governed by the pharmacokinetic characteristics of\xa0the compound. Corticosteroids like betamethasone act by inhibiting\xa0phospholipase A2.', 'role': 'assistant'}]