This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'In complication of falciparum malaria, which drug is not given - \nSelect and explain. \nA. Phenobarbitone, B. Dexmethosone, C. Quinine, D. Blood transfusion', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Cerebral malaria\n\nMany adjuvant therapies have been suggested based on the prevailing pathophysiology and hypothesis of the time.\nThese include heparin, low molecular weight dextran, urea, high dose corticosteroid, aspirn, prostacycline, pentoxifflline, desferioxamine, anti TNF antibody, cyclosporin and hyperimmune serum.\nUnfortunately, none have proved beneficial and several have proved harmful none of these adjuvants should be\xa0used, the cornerstone of management is good intensive care and correct antimalarial treatment.\n\nManagement of cerebral malaria\nAntimalarial treatment\n\nIn cerebral malaria rapidly acting parenteral drugs should be given. Quinine is the drug of choice.\n\nFluid balance\n\nFollowing admission patient should be rehydrated to a CVP of approximately 5 cm\n\nHypoglycemia\n\nSlow intravenous injection of 50% dextrose water\n\nLactic acidosis\n\nHypovolemia should be corrected first\n\nAcute renal failure\n\nFluid should be restricted to replace insensible losses only. Dialysis should be started early when there is evidence of multiple organ dysfunction.\n\nAcute pulmonary edema\n\nThey should be nursed upright and given oxygen and the right-sided filling pressure should be reduced\n\nBleeding\n\nLess than 5% of patients of cerebral malaria develop D.I.C. These patients should be given a fresh blood transfusion and vitamin K.\n\nBacterial superinfection / continued fever\n\nPatient with secondary pneumonia should be given empirical treatment with a third-generation cephalosporin.', 'role': 'assistant'}]