This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetics, Subject name: Pathology
[{'content': 'Increasing severity of mental retardation of male members over generations is a result of - \nSelect and explain. \nA. Mitochondrial DNA mutation, B. Frameshift mutation, C. Y linked disorder, D. Trinucleotide repeat mutation', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans. (d) Trinucleotide repeat mutation(Ref: Robbins 9th/pg 168-171; 8th/pg 168-171)Increasing severity of mental retardation of male members over generations is a result of "anticipation", seen in disorders caused by Trinucleotide repeat mutation. Eg Fragile X syndrome', 'role': 'assistant'}]