This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
[{'content': 'Which of the following statements about changes in aicular cailage with aging is not TRUE? \nSelect and explain. \nA. Total proteoglycan content is decreased, B. Synthesis of proteoglycans is decreased, C. Total water content of cailage is decreased, D. Enzymatic degradation of proteoglycans is increased', 'role': 'user'}, {'content': 'Answer: D \nExplanation: In ageing there will be no increase in enzymatic degradation of proteoglycans. The enzymatic degradation is slow and constant throughout the life. Ref: Biology of Cailage Cells, Stockwell, R.A, 1976, 1st Edition, Page 245; Osteoahritis : A companion to Rheumatology, Elsevier, 1st Edition, 2007, Page 79.', 'role': 'assistant'}]