This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': 'Trans-placental spread is least associated with? \nSelect and explain. \nA. HSV, B. Rubella, C. HBV, D. HIV', 'role': 'user'}, {'content': 'Answer: A \nExplanation: HSV infection may be acquired in utero, during the birth process, or during the neonatal period.\nIntrauterine and postpartum infections occur infrequently. \nMost cases of neonatal herpes result from maternal infection and transmission, usually during passage through a contaminated infected birth canal of a mother with asymptomatic\xa0genital herpes.', 'role': 'assistant'}]