This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nerve Physiology, Subject name: Physiology
[{'content': 'Repolarization is due to opening of which channels- \nSelect and explain. \nA. Na, B. HC03, C. K, D. Cl', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans. is \'c\' i.e., K Phases of Action Potentialo The action potential, which is recorded using an intracellular electrode, has following phases : -Resting stage : - This is the resting membrane potential before the action potential. At rest, membrane is said to be "polarized" because - 70 mV negative membrane potential (RMP) that is present. Strictly speaking, it is not a part of the action potential.Depolarization phase : - The potential shoots up to + 35 mV in less than a millisecond. It is due to opening of "voltage gated\'\' Na* channels which causes influx of sodium, so inside negative charge becomes positive. From - 70 mV to -55 mV (firing Ivel or threshold point) the voltage gated sodium channles open partially. This portion ofAP(- 70 mV to -55 mV) is called "prepotential"or "footof AP". Once the threshold level (-55 mV) is reached voltage gated Na+ channels open completely and the potential shoots up suddenly. It is called depolarization, since it represents loss of the original polarity of cell membrane.Repolarization phase : - The potential drops to near resting level, i.e., reversal to original polarity (repolarization). At the start of repolarization (end of depolarization), Voltage - gated Na+ channels close and Voltage - gated K+ channels open which cause efflux of K\' out of the ceil. So, inside positive charge onceagain becomes negative due to efflux of positive charge (K+).After depolarization: - The repolarization is very fast till 70% of repolarization has been acheived. After that it is slows down. This slower phase of repolarization is called \'after depolarizationAfter-hyperpolarization : - The intracellular negativity overshoots the normal RMP of - 70 mV to reach a more negative value of about - 75 mV and then slowly retruns to the normal RMP of - 70 mV.', 'role': 'assistant'}]