This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General Microbiology Pa 1 (History, Microscopy, Stains and Structure and Physiology of Bacteria), Subject name: Microbiology
[{'content': 'F plasmid of high frequency recombination is \nSelect and explain. \nA. Extrachromosomal, B. Chromosomal, C. Mesosome, D. Ribosomes', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Hfr Conjugation: F factor being a plasmid, is always Extra-chromosomal It may integrate with bacterial chromosome and behave as episome. Such donor cells are able to transfer chromosomal DNA to recipient cells with high frequency in comparison to F+ cells, therefore, named as Hfr cells (high frequency of recombination). During conjugation of Hfr cell with an F- cell, only few chromosomal genes along with only a pa of the F factor get transferred. Hence, F- recipient cells do not become F+ cells.', 'role': 'assistant'}]