This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Renal carcinoma, Subject name: Pathology
[{'content': 'Which of the following RCC do not have papillary architecture in histology ? \nSelect and explain. \nA. Xp11 translocation carcinoma, B. Bellini duct carcinoma, C. Succinate dehydrogenase-deficient RCC, D. Papillary carcinoma', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Succinate dehydrogenase deficient renal cell carcinoma (SDD-RCC) It is very rare type of RCC It is defined by WHO as a malignant epithelial tumor, composed of vacuolated eosinophilic to clear cells with loss of immunohistochemical expression of SDHB gene. Features : Characteristic flocculent cytoplasmic vacuoles with a pale eosinophilic, bubbly appearance and low grade nuclei Image : SDD-RCC showing cytoplasmic vacuoles which impas a bubbly appearance.', 'role': 'assistant'}]