This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrine, Subject name: Pathology
[{'content': "A patient presents with Endocrinopathy, fibrous dysplasia of bone and hyperpigmentation. Diagnosis is? \nSelect and explain. \nA. McCune Albright syndrome, B. Addison's disease, C. Alagille syndrome, D. Lynch syndrome", 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. (a) McCune Albright syndrome(Ref: Robbins 9th/pg 1206-1207)McCune-Albright syndromeGeneticsIt is due to GNAS mutation - continuous activation of stimulatory G proteinPatho physiologyIncreased production of hormones by glands regulated by the G protein systemClinical featuresPrecocious puberty, Polyostotic fibrous dysplasia, unilateral Cafe au lait spots', 'role': 'assistant'}]