This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Lukemia, Subject name: Pathology
[{'content': 'AML - bad prognostic factor is? \nSelect and explain. \nA. Preceding MDS, B. Inv 16, C. Auer rods, D. Type M4', 'role': 'user'}, {'content': "Answer: A \nExplanation: Ans. is 'a' i.e., Preceding MDS Prognostic factors in AMLo Age < 40 yearso Age < 2 years or > 55 yearso M2, M3, M4 forms of AMLo MO, M6, M7 forms of AMLo Blast cell with Auer rodso Complex karyotypeso TLC<25 x 109/LoTLC> 100 x 109/Lo t(15; 17), t (8;21), invl6o Deletions 5q, 7q (Monosomy 5 or 7)o Leukemia without preceeding MDSo AML with preceding MDS or anticancer drug exposure", 'role': 'assistant'}]