This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Structure and function of protein, Subject name: Biochemistry
[{'content': 'In Gaucher&;s disease, there is a deficiency of \nSelect and explain. \nA. Glucocerebrosides, B. glucokinase, C. Sphingomyelinase, D. G-6PD', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Due to deficiency of glucocerebrosidase, causes glucosylceramide accumulation in macrophages called Gaucher&;s cells.DiseaseEnzyme DeficiencyClinical SymptomsGaucher diseaseb-GlucosidaseEnlarged liver and spleen, erosion of long bones,mental retardation in infantsRef: Harper&;s biochemistry; 30th edition; Chapter 24 Metabolism of Acylglycerols & Sphingolipids', 'role': 'assistant'}]