This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'Absolute contraindication to Hormone replacement therapy \nSelect and explain. \nA. Osteoporosis, B. Otosclerosis, C. Colon cancer, D. Premature menopause', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Absolute conrtraindications to HRT\n\nSuspected pregnancy\nBreast cancer\nEndometrial cancer\nActive\xa0liver disease\nKnown thrombophilia\nOsteosclerosis.', 'role': 'assistant'}]