This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Medicine
[{'content': 'Poorest prognosis in AML is seen in which cyiogcnetic abnormality- \nSelect and explain. \nA. Monosomy 7, B. No cytogenetic abnormality, C. t(l5,i7), D. inv, 16', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Monosomy 7 or paial deletion of the long arm of chromosome 7 (7q-) is a frequent cytogenetic finding in the bone marrow of patients with myelodysplasia (MDS) and acute myelogenous leukemia (AML) Ref Davidson 23rd edition pg 789', 'role': 'assistant'}]