This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Central Nervous system, Subject name: Pharmacology
[{'content': 'Which of the following is a specific inhibitor of the enzyme alcohol dehydrogenase and is useful in the treatment of methanol poisoning \nSelect and explain. \nA. Disulfiram, B. Ethylene glycol, C. Calcium leucovorin, D. Fomepizole', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Fomepizole (4-methylpyrazole):- It is a specific inhibitor of alcohol dehydrogenase and the drug of choice for methanol poisoning by retarding its metabolism. Dosage:- A loading dose of 15 mg/kg i.v. followed by 10 mg/kg every 12 hours till serum methanol falls below 20 mg/dl, has been found effective and safe. Ref:- kd tripathi; pg num:-395', 'role': 'assistant'}]