This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hydramnios and Oligo Hydramnios, Subject name: Gynaecology & Obstetrics
[{'content': 'Which of the following congenital anomalies is seen with maternal use of cocaine: \nSelect and explain. \nA. Sacral agenesis, B. Hydrops, C. Cerebral infarction, D. Hypertrichosis', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Ans. C. Cerebral infarctionCocaine - use has been associated with MI, arrhythmias aortic rupture, strokes seizures, bowel ischemia, hyperthermia, and sudden deatha. Risk of vascular disruption within the embryo-fetus or placenta is highest after the first trimester and likely accounts for the increased incidence of stillbirthsb. A number of cocaine related congenital anomalies due to vascular based disruption, they include skull defect, cutis aplasia, porencephaly, ileal atresia, cardiac anomalies and visceral infarctsDrug of abuse during pregnancy -Cocaine - LBW, preterm delivery, increased placental abrupt us, increased fetal death, fetal tachycardia and hypertension, CNS irritability, cerebral infarctCaffeine - Increased miscarriage and still birthsMarijuana - Thymic hypoplasia', 'role': 'assistant'}]