This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Adrenal Gland, Subject name: Pathology
[{'content': 'A tentatively female newborn has ambiguous genitalia. What appears to be a vagina is associated with a significantly enlarged clitoris resembling a penis. Other findings include hyponatremia, hyperkalemia, and hypotension. Deficiency of which of the following is suggested by these findings? \nSelect and explain. \nA. 11-Hydroxylase, B. 17-Hydroxylase, C. 21-Hydroxylase, D. Amylin', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Deficiency of enzyme 21-hydroxylase (mc) 11 hydroxylase 17 hydroxylase | Coisol | Mineralocoicoids (Salt losing hypotension) | Sex hormones(Virilization) Similar to 21 hydroxylase except | Deoxycoicosterone (Hypeension) | Coisol | Mineralocoicoid | Sex hormone', 'role': 'assistant'}]