This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'The epithelioid cell is a modified- \nSelect and explain. \nA. Macrophage, B. Lymphocyte, C. Mast cell, D. Eosinophil', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Granulomatous inflammation\xa0is a form of chronic inflammation\xa0characterized by collections of activated\xa0macrophages. often with T lymphocytes, and sometimes associated\xa0with central necrosis.\nThese granulomas are type IV hypersensitivity reaction\xa0that involves CD4-helper T-ceIIs.\nHelper T-cells are activated\xa0by IL-2 and produce IFN-γ (interferon gamma) the major cytokine of\xa0granulomatous inflammation.\n\n□ IFN-γ induces the formation\xa0of granuloma by conversion of activated\xa0macrophages into epithelioid\xa0cells and the formation\xa0of giant cells by fusion of epithelial cells,', 'role': 'assistant'}]