This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Heart, Circulation, and Blood, Subject name: Physiology
[{'content': 'An arteriole with a damaged endothelial cell layer will not: \nSelect and explain. \nA. Constrict when intravascular pressure is increased, B. Dilate when adenosine is applied to the vessel wall, C. Constrict in response to norepinephrine, D. Dilate in response to adenosine diphosphate (ADP) or acetylcholine', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans. D. Dilate in response to adenosine diphosphate (ADP) or acetylcholineBoth adenosine diphosphate (ADP) and acetylcholine cause the release of NO from endothelial cells. The other choices involve mechanisms that function without endothelial cells.', 'role': 'assistant'}]