This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Medicine
[{'content': 'The poor prognostic factor associated with ALL in children is - \nSelect and explain. \nA. Total leucocyte count 4000-10000, B. Age more than 2 years, C. Testicular involvement, D. Female gender', 'role': 'user'}, {'content': 'Answer: C \nExplanation: High risk factors in ALL are age belw 1yr & more than 10 yr, male gender, wbc count more than 50,000/cubic millimeter .,massive hepatomegaly,lymphadenopathy,mediastinal mass,central nervous system leukemia ,mature B cell as phenotype,hypodiploidy.Reference :Op Ghai essentials of pediatrics 8th edition pg no 601.', 'role': 'assistant'}]