This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
[{'content': 'ADAMS 13 mutation is responsible for: \nSelect and explain. \nA. TTP, B. HUS, C. DIC, D. ITP', 'role': 'user'}, {'content': 'Answer: A \nExplanation: The pathogenesis of inherited or idiopathic TTP is related to the deficiency or antibodies to the metalloprotease ADAMTS13 that cleaves the vWF. Ref: Harrison, Edition-18, Page - 965', 'role': 'assistant'}]