This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
[{'content': "A malignant tumor of childhood, that metastasizes to bones most often, is: \nSelect and explain. \nA. Wilm's tumor, B. Neuroblastoma, C. Adrenal gland tumors, D. Granulose cell tumor of ovary", 'role': 'user'}, {'content': 'Answer: B \nExplanation: Neuroblastoma is the most common solid neoplasm outside the CNS. It arises from neural crest tissue of the sympathetic ganglia or adrenal medulla. It most commonly metastasize to bone, bone marrow, lymph nodes, liver and subcutaneous tissue. It has a predilection for metastasis to the skull, paicularly the sphenoid bone and retrobulbar tissue. Ref: Essential Pediatrics By O P Ghai, 6th Edition, Page 573; CURRENT Diagnosis and Treatment: Pediatrics, 20th Edition, Chapter 29.', 'role': 'assistant'}]