This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
[{'content': 'Nifedipine and beta-blocker are given together - \nSelect and explain. \nA. To decrease pedal edema due to nifedipine, B. To overcome increased sympathetic activity of nifedipine, C. Anti CHF action of propranolol, D. Antiarrhythmic effect of nifedipine', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., To overcome increased sympathetic activity of Nifedipine b-Blocker is given along with Nifedipine because a) Reflex tachycardia (Increased sympathetic activity) caused due to Nifedipine, is prevented by b-blocker. b) b-blockers cause dilatation of coronary aeries by unopposed a-mediated vasoconstriction. Nifedipine causes coronary vasodilatation and opposes the spasm caused by b-blockers. The tendency of b-blocker to cause ventricular dilatation is counteracted by Nifedipine.", 'role': 'assistant'}]