This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Enzymes, Subject name: Biochemistry
[{'content': "Regan isoenzyme is increased in \nSelect and explain. \nA. Seminoma, B. Paget's disease, C. Osteoporosis, D. Cholestasis", 'role': 'user'}, {'content': 'Answer: A \nExplanation: The Regan isoenzyme is a placental-type alkaline phosphatase that is expressed in a number of human tumors, paicularly in gonadal and urologic cancers. Evidence now points to seminoma as a consistent producer of Regan isoenzyme although much more work will be required to establish its clinical utility. Ref:', 'role': 'assistant'}]