This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Inhalational Anesthetic Agents, Subject name: Anaesthesia
[{'content': 'Volatile agent which causes most renal toxicity is \nSelect and explain. \nA. Ether, B. Isoflurane, C. Methoxyflurane, D. Sevoflurane', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Methoxyflurane is most metabolized and produces more than 80 micromol/litre of flouride in blood. The amount of fluoride ions produced: Methoxyflurane: 50uM Sevoflurane: 20-30 uM Enflurane: 20uM Isoflurane and desflurane: 5uM', 'role': 'assistant'}]