This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy, Subject name: Pharmacology
[{'content': 'Topical mitomycin-C is used in: (REPEAT) \nSelect and explain. \nA. Sturge-Weber syndrome, B. Laryngotracheal stenosis, C. Endoscopic angiofibroma, D. Skull base osteomyelitis', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Mitomycin-C is an antineoplastic antibiotic that acts as an alkylating agent by inhibiting DNA and protein synthesis. It can inhibit cell division, protein synthesis, and fibroblast proliferation. Topical application of mitomycin-C (0.4 mg/mL) was used as an adjuvant treatment in the endoscopic laser management of laryngeal and tracheal stenosis. REFERENCE: www.ncbi.nlm.nih.gov', 'role': 'assistant'}]