This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Renal physiology, Subject name: Physiology
[{'content': 'Ist urge of micturition comes at \nSelect and explain. \nA. 50ml, B. 150ml, C. 250ml, D. 350ml', 'role': 'user'}, {'content': 'Answer: B \nExplanation: When 100-150 millilitres (3.5-5 ounces) of urine accumulate, the first sensations of a need to void are felt. The feeling increases in intensity as more urine accumulates, and it becomes uncomfoable at a bladder volume of 350-400 millilitres. Impulses from the pelvic nerves mediate the sensations of bladder filling, painful distension, and the conscious need to urinate. Ref: guyton and hall textbook of medical physiology 12 edition page number:519,520,521', 'role': 'assistant'}]