This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Anaesthesia
[{'content': 'Nephrotoxic agent is – \nSelect and explain. \nA. Methoxy flurone, B. Isoflurone, C. Halothane, D. N2O', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Methoxyflurane is most nephrotoxic can cause high output (polyuric) renal failure.', 'role': 'assistant'}]