This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Sedative-Hypnotics and Parkinsonism, Subject name: Pharmacology
[{'content': 'The selective MAO-B inhibitor out of the following is: \nSelect and explain. \nA. Selegiline, B. Clorgyline, C. Moclebemide, D. Tranylcypromine', 'role': 'user'}, {'content': 'Answer: A \nExplanation: -Selegiline and rasagiline Also called as Deprenyl Irreversible and selective MAO-B inhibitors Inhibits MAO-A at higher doses only It has neuroprotective and antiapoptotic effects Use: Oral dose is used in on- off phenomenon in Parkinsonism Transdermal patch is used for depression Incidence of cheese reaction is minimal Causes insomnia so used in morning and afternoon -Moclebemide is selective reversible MAO-A inhibitor for depression. Whereas clorgyline is irreversible MAO-A inhibitor -Tranylcypromine is a non-selective MAO inhibitor.', 'role': 'assistant'}]