This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'Most common cause of splenic rupture is - \nSelect and explain. \nA. Malaria, B. ITP, C. Thalassemia, D. Cirrhosis', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Most common cause of splenic rupture is Trauma.\nIn the absence of trauma Spontaneous rupture of spleen occurs due to some minor physical insult to a spleen that has been rendered fragile by an underlying condition. The most common predisposing conditions are IMN, malaria, typhoid fever and lymphoid neoplasms.', 'role': 'assistant'}]