This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
[{'content': 'True about fresh frozen plasma -a) Used for treatment of antithrombin-3 deficiencyb) Used for treatment of Vit-K deficiencyc) Used for replacing factor VIII & IX, if deficiencyd) Best alternative for platelet \nSelect and explain. \nA. ac, B. a, C. ad, D. ab', 'role': 'user'}, {'content': "Answer: D \nExplanation: Fresh frozen plasma (FFP)\xa0\n\nFFP is defined as the fluid portion of human blood that has been centrifuged, separated, and frozen solid at -18°c within 6 hours.\nFFP contains stable coagulation factors and plasma proteins : -\n\ti. Fibrinogen\n\tii. Antithrombin\xa0\xa0\n\tiii.\xa0Albumin & Immunoglobulin \xa0 \xa0 \xa0\n\tiv. Protein C,S\xa0\n\tv.\xa0Factor II, V, VII, ix, X, XI\xa0\n\nUses\n\nThere are few specific indications for the the use of FFP.\nThese indications are generally limited to the treatment of deficiency of coagulation proteins for which specific factor concentrates are unavailable or undesirable.\n\nIndications for the use of FFP are : -\n\nDeficiencies of factor II, V, VII, IX, X and XI when specific component therapy is neither available nor appropriate.\nEmergency reversal of warfarin effect.\nIn vit K deficiency as replacement for Vit K dependent factors (II, VII, IX, X)\nAntithrombin III deficiency\nAfter massive blood transfusion.\nIn immunodeficiency as a source of immunoglobulin\nTTP\n\nNote\xa0: Options 'c' is partially correct, PPP can be used for deficiency of factor IX but not for factor VIII.", 'role': 'assistant'}]