This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Lipoproteins, Subject name: Biochemistry
[{'content': 'A patient with a history of recurring attacks of pancreatitis, eruptive xanthomas, and increased plasma triglyceride levels (2,000 mg/dL). Which of the following is the most likely deficiency: \nSelect and explain. \nA. Lipoprotein Lipase, B. LDL receptors, C. HMG-CoA reductase, D. ABCA1 receptor', 'role': 'user'}, {'content': "Answer: A \nExplanation: In this patient, Accumulation of TGs leads to Eruptive xanthomas | risk of acute pancreatitis Milky plasma suggests | Chylomicrons Due to the defect in lipoprotein lipase enzyme Characteristic of familial hyperchylomicronaemia. LDL receptor defect leads to accumulation of LDL, not TGs -(option b) is excluded. Complete deficiency of HMG-CoA reductase Lethal Incompatible with life -(option c) is excluded. ABCA1 defect leads to Tangier's disease - (option d) is excluded.", 'role': 'assistant'}]