This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetic and genetic disorders, Subject name: Pediatrics
[{'content': 'Down Syndrome, All are seen except \nSelect and explain. \nA. t (14 ; 21), B. Trisomy 21, C. t (11:14), D. t (15:21)', 'role': 'user'}, {'content': 'Answer: C \nExplanation: Majority of translocations in Down syndrome are fusions at the centromere between chromosomes 13,14,15,21 and 22.These are known as Robeson I an translocation. t(11:14 ) is not seen in down syndrome. Reference : Nelson TB of pediatrics 19th edition pg 402.', 'role': 'assistant'}]