This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Pharmacology
[{'content': 'TRUE ABOUT NON - COMPETITIVE INHIBITION IS ? \nSelect and explain. \nA. Km remains same ,Vmax decrease, B. Km increase , Vmax increase, C. Km decrease , Vmax increase, D. Km increase, Vmax increases', 'role': 'user'}, {'content': 'Answer: A \nExplanation: ref : KD TRIPATHI 8TH ED', 'role': 'assistant'}]