This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of carbohydrate, Subject name: Biochemistry
[{'content': "Sandhoff's disease is d/t absence of which enzyme? \nSelect and explain. \nA. Beta-hexosaminidase, B. Beta-glucuronibase, C. Aryl sulphatase, D. Alpha galactosidase", 'role': 'user'}, {'content': 'Answer: A \nExplanation: It is a lipid storage disease.Due to deficiency of hexaminidase.Leads to accumulation of globoside (Table;14.4)Ref: DM Vasudevan, 7th edition, page no: 193', 'role': 'assistant'}]