This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Epidemiology, Subject name: Social & Preventive Medicine
[{'content': 'The most difficult criterion to establish Causal association in etiology of a disease is- \nSelect and explain. \nA. Temporality, B. Strength of association, C. Specificity of association, D. Biological plausibility', 'role': 'user'}, {'content': "Answer: C \nExplanation: Specificity of association means that the disease is caused by a paicular risk factor. It is difficult criterion to establish, as it is difficult to rule out the same outcomes by other exposures. Other Hill's criteria of causal association/ Surgeon general's criteria include: Temporality Consistency Strength Biological plausibility Coherence Dose response relationship Cessation of exposure.", 'role': 'assistant'}]