This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy: General Principles, Subject name: Pharmacology
[{'content': 'Which of the following antitubercular drugs can be safely used in severe renal failure? \nSelect and explain. \nA. Streptomycin, B. Ethambutol, C. Capreomycin, D. Rifampicin', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Ans. (D) Rifampicin(Ref: KDT 8th/e p818)Streptomycin and capreomycin are nephrotoxic whereas ethambutol accumulates in renal failure and thus should be avoided in presence of severe renal failure.', 'role': 'assistant'}]