This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: NEET Jan 2020, Subject name: Biochemistry
[{'content': 'Which of the following is the etiology of Werner syndrome? \nSelect and explain. \nA. Increased length of telomere, B. Sho telomere with damaged DNA and loss of helicase, C. Increased advanced glycation end products, D. Decreased lipid peroxidation', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Werner syndrome: It is a hereditary condition with premature aging due to mutation in the WRN gene There is Loss of function DNA helicase. This results in the shoening of the telomeres with damaged DNA. There is increased risk of cancer in the individuals with Werner syndrome.', 'role': 'assistant'}]