This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
[{'content': 'C- peptide is secreted by ? \nSelect and explain. \nA. A cells, B. B cells, C. D cells, D. F cells', 'role': 'user'}, {'content': "Answer: B \nExplanation: Ans. is 'b' i.e., B cellsInsulin is a polypeptide hormone which is synthesized as a larger preprohormone (preproinsulin).Asthepreprohormone enters the endoplasmic reticulum, 23 amino-acid signal peptide is removed and it is conveed to prohormone (proinsulin).Proinsulin is made up A and B chain connected by a connecting peptide (C-peptide or C-chain).C-peptide is detached in the granules before secretion. Normally, 90-97% of the product released from B cells is insulin along with equimolar amounts of C-peptide.Insulin is a two chain polypeptide having 51 aminoacids : The A chain has 21 while B-chain has 30-aminoacids.Half life of insulin is about 5 minutes.", 'role': 'assistant'}]