This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Psychiatry
[{'content': 'A patient of schizophrenia on CPZ (chlorpromazine) develops auditory hallucination again. The next drug to be given is - \nSelect and explain. \nA. Haloperidol, B. Clozapine, C. Sulpiride, D. Tianeptin', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Auditory hallucinations (positive symptoms) are the first symptoms to respond. If auditory hallucinations do not respond or reappear while the patient is on treatment, resistant schizophrenia should be suspected.\n\n"Clozapine (but not newer atypicals) is more effective than classical agents for resistant schizophrenia"', 'role': 'assistant'}]