This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
[{'content': "Genetic analysis shows N-myc gene in a child. She may have the following malignancy: \nSelect and explain. \nA. Neuroblastoma, B. Retinoblastoma, C. William's tumor, D. Nephroblastoma", 'role': 'user'}, {'content': "Answer: A \nExplanation: Neuroblastoma is associated with N-myc amplification. It is associated with a poor prognosis regardless of patient age. Regression of neuroblastoma generally occurs only in tumors with a near triploid number of chromosomes that also lack N-myc amplification and loss of chromosome arm 1p. Ref: Hackam D.J., Grikscheit T.C., Wang K.S., Newman K.D., Ford H.R. (2010). Chapter 39. Pediatric Surgery. In F.C. Brunicardi, D.K. Andersen, T.R. Billiar, D.L. Dunn, J.G. Hunter, J.B. Matthews, R.E. Pollock (Eds), Schwaz's Principles of Surgery, 9e.", 'role': 'assistant'}]