This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
[{'content': 'A mother with 10 weeks pregnancy and who had previously delivered a baby with open neural tube defect which statement is true \nSelect and explain. \nA. Sodium valproate causes open neural tube defect, B. Risk of recurrence is 10%, C. Amniocentesis should be done, D. Give multivitamin', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. is a i.e Sodium valproate causes open neural tube defect Sodium valproate "used during pregnancy, has produced neural tube defects in the offspring; therefore should be avoided". KDT 5/e, p 375 Therefore option "a" is correct "The risk of recurrence of anencephaly is 5% after one affected child and 13% after two affected children deg\'\'', 'role': 'assistant'}]