This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
[{'content': 'Reverse transcriptase is a RNA dependent DNA polymerase. Which of these use it? \nSelect and explain. \nA. Hepatitis A virus, B. Hepatitis B virus, C. Hepatitis E virus, D. Hepatitis C virus', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Ans. (b) Hepatitis B virus Set ot te,, DNA polymerase of HBV has both DNA-dependent DNA polymerase and RNA-dependent reverse transcriptase activities. Not Instead of DNA replication directly from a DNA template, hepadnaviruses rely on reverse transcription (effected by the DNA polymerase) of minus-strand DNA from a "pregenomic" RNA intermediate. Then plus-strand DNA is transcribed from the minus strand DNA template by the DNA-dependent DNA polymerase and conveed in the hepatocyte nucleus to a covalently closed circular DNA, which serves as a template for messenger RNA and pregenomic RNA.', 'role': 'assistant'}]