This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Beta oxidation of fatty acids, Subject name: Biochemistry
[{'content': 'Ketogenesis takes place in: \nSelect and explain. \nA. Hepatic mitochondria, B. Hepatic cytoplasm, C. Hepatic microsome, D. Hepatic lysosome', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Fatty acid oxidation takes place in mitochondria. Ketogenesis also takes place in mitochondria. HMG-CoA synthase is present in both cytosol and mitochondria. Cytosolic HMG-CoA synthase is involved in cholesterol synthesis. Mitochondrial HMG-CoA synthase is involved in ketogenesis.', 'role': 'assistant'}]