This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'In which of the following types of Carcinoma Breast, Comedo growth pattern in seen ? \nSelect and explain. \nA. Ductal carcinoma in situ, B. Medullary carcinoma, C. Lobular carcinoma in situ, D. Infiltrating lobular carcinoma', 'role': 'user'}, {'content': 'Answer: A \nExplanation: - Historically, ductal carcinoma in situ (intraductal carcinoma) has been divided\ninto five architectural subtypes : comedocarcinoma, solid, cribriform, papillary and micropapillary.\nComedocarcinoma is characterized by solid sheets of pleomorphic cells with high grade nuclei and central necrosis\nThe necrotic cell membranes commonly calcify and are detected on mammography as clusters of linear and branching microcalcifications.', 'role': 'assistant'}]