This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
[{'content': 'Physostigmine was therapeuticallyused for the first time in treatment of glaucoma in 1877 by – \nSelect and explain. \nA. Laqueur, B. Posselt and Reiman, C. Ahlquist, D. Sir James Black', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Laqueur\nPosselt and Reiman isolated nicotine from the leaves of Nicotiana tabacum.\nAhlquist gave the hypothesis that adrenaline acts on different sets of receptors, later named as α and β.\nSir James Black synthesized the first β-blocker, dichloroisoproterenol, and subsequently, propranolol.', 'role': 'assistant'}]