This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Acne and chemical peeling, Subject name: Dental
[{'content': 'Causative factor acne are following except: \nSelect and explain. \nA. Androgen, B. Oily food, C. Bacterial proliferation, D. Hypercornification of duct', 'role': 'user'}, {'content': 'Answer: B \nExplanation: Acne is a chronic inflammatory disease of the pilosebaceous units, skin structures consisting of a hair follicle and its associated sebaceous gland Major factors are involved in the pathogenesis: - Hormonal factors (| androgens, Insulin resistance, Insulin growth factor-1(IGF-1) - | IL-1a activity - | Lenoleic acid - Increased sebum production k/a Seborrhea, - Hypercornification of the pilosebaceous duct, - Abnormality of the microbial flora especially colonization of the duct with Cutibacterium acnes. - The activity of bacteria (C.acnes) within the comedones releases free fatty acids from sebum, causes inflammation within the cyst, and results in rupture of the cyst.', 'role': 'assistant'}]