This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: JIPMER 2017, Subject name: Pathology
[{'content': 'Which of the following is the best candidate for allogenic bone marrow transplant? \nSelect and explain. \nA. 6 year old with thalassemia minor, B. Autoimmune disease, C. Multiple myeloma, D. Hereditary immunodeficiency', 'role': 'user'}, {'content': 'Answer: D \nExplanation: Bone marrow transplantation usually involves two types: Allogenic: mainly for Acute leukemic patient Autologous: mainly for Multiple myeloma and Non Hodgkin Lymphoma Graft failure/rejection is a significant complication following hematopoietic cell transplantation (HCT). It may be due to rejection caused by recipient T-cells, NK-cells or antibodies. Bone marrow transplantaion is successful in patient with SCID as they are deficient with immunogenic cell and immunodeficiency, which makes them best candidate for allogenic bone marrow transplant.', 'role': 'assistant'}]