This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Adverse Drug Effect, Subject name: Pharmacology
[{'content': 'Irreversible ototoxicity is caused by - \nSelect and explain. \nA. Cisplatin, B. Cyclophosfamide, C. Bleomycin, D. Chlorambucil', 'role': 'user'}, {'content': 'Answer: A \nExplanation: Ans. is \'a\' i.e., Cisplatin "Cisplatin induced hearing loss is usually bilateral and irreversible"Drugs causing ototoxicityA) Vestibular (primarily)o Aminoglycosides o Mustineo Quinidineo Quinineo Chloroquineo Vancomycino Furosemide o Ethacrynic acido Salicylates (high dose)B) Auditory (primarily)o NSAIDso Ethacrynic acido Vancomycino Aminoglycosideso Cisplatin', 'role': 'assistant'}]