PatentNumber
stringlengths 10
12
| Year
int64 1.98k
2.02k
| reactions
stringlengths 20
1.76k
| canonical_reactions
stringlengths 20
1.76k
|
|---|---|---|---|
US09448237B2 | 2,016 | C=CCOC(=O)[C@H](Cc1ccc(OP(=O)(Cc2ccccc2)Cc2ccccc2)c(N=[N+]=[N-])c1)NC(=O)OCC1c2ccccc2-c2ccccc21.CCOC(C)=O.CNc1ccccc1.O=S(=O)([O-])O.[K+]>C1COCC1>[N-]=[N+]=Nc1cc(C[C@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)ccc1OP(=O)(Cc1ccccc1)Cc1ccccc1 | C=CCOC(=O)[C@H](Cc1ccc(OP(=O)(Cc2ccccc2)Cc2ccccc2)c(N=[N+]=[N-])c1)NC(=O)OCC1c2ccccc2-c2ccccc21.CCOC(C)=O.CNc1ccccc1.O=S(=O)([O-])O.[K+]>C1COCC1>[N-]=[N+]=Nc1cc(C[C@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)ccc1OP(=O)(Cc1ccccc1)Cc1ccccc1 |
US09449726B2 | 2,016 | F[C-](F)[O+]=C(Cl)C(F)(F)F.O=P(O)(O)CP(=O)(O)O.O=[99Tc](=O)(=O)[O-].O=[PH]1OCO[PH](=O)O1.[Na+]>>O=P([O-])([O-])CP(=O)([O-])[O-].[99Tc+4].[OH3+].[OH3+] | F[C-](F)[O+]=C(Cl)C(F)(F)F.O=P(O)(O)CP(=O)(O)O.O=[99Tc](=O)(=O)[O-].O=[PH]1OCO[PH](=O)O1.[Na+]>>O=P([O-])([O-])CP(=O)([O-])[O-].[99Tc+4].[OH3+].[OH3+] |
US09449732B2 | 2,016 | C(=NC1CCCCC1)=NC1CCCCC1.CCCCCCOc1ccc(O)cc1.O.O=C(O)c1ccc(OCc2ccccc2)cc1>CN(C)C1C=CN=CC=1.C(Cl)Cl>CCCCCCOc1ccc(OC(=O)c2ccc(OCc3ccccc3)cc2)cc1 | C(=NC1CCCCC1)=NC1CCCCC1.CCCCCCOc1ccc(O)cc1.O.O=C(O)c1ccc(OCc2ccccc2)cc1>CN(C)C1C=CN=CC=1.C(Cl)Cl>CCCCCCOc1ccc(OC(=O)c2ccc(OCc3ccccc3)cc2)cc1 |
US09449732B2 | 2,016 | C1=CCC=CC1.CCCCCCOc1ccc(OC(=O)c2ccc(OCc3ccccc3)cc2)cc1>[Pd].C1COCC1>CCCCCCOc1ccc(OC(=O)c2ccc(O)cc2)cc1 | C1=CCC=CC1.CCCCCCOc1ccc(OC(=O)c2ccc(OCc3ccccc3)cc2)cc1>[Pd].C1COCC1>CCCCCCOc1ccc(OC(=O)c2ccc(O)cc2)cc1 |
US09450175B2 | 2,016 | CC(=O)[O-].CC(=O)[O-].[K+].[Na+]>COCCO>CC(=O)[O-].CC(=O)[O-].[K+].[Na+] | CC(=O)[O-].CC(=O)[O-].[K+].[Na+]>COCCO>CC(=O)[O-].CC(=O)[O-].[K+].[Na+] |
US09450175B2 | 2,016 | CC(=O)[O-].CC(=O)[O-].[K+].[Na+]>COCCO>CC(=O)[O-].CC(=O)[O-].[K+].[Na+] | CC(=O)[O-].CC(=O)[O-].[K+].[Na+]>COCCO>CC(=O)[O-].CC(=O)[O-].[K+].[Na+] |
US09450174B2 | 2,016 | Cc1ccc(S(=O)(=O)O)cc1.N[C@@H](CCC(=O)O)C(=O)O.O.OCC1CC2CCC1C2>ClCCCl>N[C@@H](CC(CC1CC2CCC1C2)C(=O)O)C(=O)O.N[C@@H](CC(Cc1ccccc1)C(=O)O)C(=O)O | Cc1ccc(S(=O)(=O)O)cc1.N[C@@H](CCC(=O)O)C(=O)O.O.OCC1CC2CCC1C2>ClCCCl>N[C@@H](CC(CC1CC2CCC1C2)C(=O)O)C(=O)O.N[C@@H](CC(Cc1ccccc1)C(=O)O)C(=O)O |
US09450174B2 | 2,016 | CC1C[C@H](NC(=O)O)C(=O)OC1=O.CN(C)CCCN.O=C(O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)OC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)O>ClCCCl>CC(C[C@H](N)C(=O)O)C(=O)O.N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O | CC1C[C@H](NC(=O)O)C(=O)OC1=O.CN(C)CCCN.O=C(O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)OC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)O>ClCCCl>CC(C[C@H](N)C(=O)O)C(=O)O.N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O |
US09450174B2 | 2,016 | CC1C[C@H](NC(=O)O)C(=O)OC1=O.CN(C)CCCN.O=C(O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)OC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)O>ClCCCl>CC(C[C@H](N)C(=O)O)C(=O)O.N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O | CC1C[C@H](NC(=O)O)C(=O)OC1=O.CN(C)CCCN.O=C(O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)OC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)O>ClCCCl>CC(C[C@H](N)C(=O)O)C(=O)O.N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O |
US09450174B2 | 2,016 | CN(C)CCCN.O=C(O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)OC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)O.O=C(O)N[C@H]1CC(Cc2ccccc2)C(=O)OC1=O>ClCCCl>N[C@@H](CC(Cc1ccccc1)C(=O)O)C(=O)O.N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O | CN(C)CCCN.O=C(O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)OC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)O.O=C(O)N[C@H]1CC(Cc2ccccc2)C(=O)OC1=O>ClCCCl>N[C@@H](CC(Cc1ccccc1)C(=O)O)C(=O)O.N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O |
US09450174B2 | 2,016 | CN(C)CCCN.O=C(O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)OC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)O.O=C(O)N[C@H]1CC(Cc2ccccc2)C(=O)OC1=O>ClCCCl>N[C@@H](CC(Cc1ccccc1)C(=O)O)C(=O)O.N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O | CN(C)CCCN.O=C(O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)OC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)O.O=C(O)N[C@H]1CC(Cc2ccccc2)C(=O)OC1=O>ClCCCl>N[C@@H](CC(Cc1ccccc1)C(=O)O)C(=O)O.N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O |
US09450174B2 | 2,016 | CC(C[C@H](N)C(=O)O)C(=O)O.CCCCCCC(C[C@H](N)C(=O)O)C(=O)O>>CC(C[C@H](N)C(=O)O)C(=O)O.CCCCCCC(C[C@H](N)C(=O)O)C(=O)O | CC(C[C@H](N)C(=O)O)C(=O)O.CCCCCCC(C[C@H](N)C(=O)O)C(=O)O>>CC(C[C@H](N)C(=O)O)C(=O)O.CCCCCCC(C[C@H](N)C(=O)O)C(=O)O |
US09450174B2 | 2,016 | N[C@@H](CC(Cc1ccccc1)C(=O)O)C(=O)O.N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O>>N[C@@H](CC(Cc1ccccc1)C(=O)O)C(=O)O.N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O | N[C@@H](CC(Cc1ccccc1)C(=O)O)C(=O)O.N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O>>N[C@@H](CC(Cc1ccccc1)C(=O)O)C(=O)O.N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O |
US09450192B2 | 2,016 | CC(=O)n1c2ccccc2c2cc(Br)ccc21.c1ccc(N(c2ccccc2)c2ccc(Nc3cccc4ccccc34)cc2)cc1>[Cu]=O>c1ccc(N(c2ccccc2)c2ccc(N(c3ccc4[nH]c5ccccc5c4c3)c3cccc4ccccc34)cc2)cc1 | CC(=O)n1c2ccccc2c2cc(Br)ccc21.c1ccc(N(c2ccccc2)c2ccc(Nc3cccc4ccccc34)cc2)cc1>[Cu]=O>c1ccc(N(c2ccccc2)c2ccc(N(c3ccc4[nH]c5ccccc5c4c3)c3cccc4ccccc34)cc2)cc1 |
US09450192B2 | 2,016 | Brc1cccc(-c2ccc(-c3ccccc3)cc2)c1.O=P([O-])([O-])[O-].[K+].[K+].[K+].c1ccc2c(c1)N=c1c-2ccc2c1=Nc1ccccc1-2>C1(C)C=CC=CC=1.[Pd].[Pd].C(=CC(C=CC1C=CC=CC=1)=O)C1C=CC=CC=1.C(=CC(C=CC1C=CC=CC=1)=O)C1C=CC=CC=1.C(=CC(C=CC1C=CC=CC=1)=O)C1C=CC=CC=1.C(P(C(C)(C)C)C(C)(C)C)(C)(C)C>c1ccc(-c2ccc(-c3cccc(-n4c5ccccc5c5ccc6c7ccccc7[nH]c6c54)c3)cc2)cc1 | Brc1cccc(-c2ccc(-c3ccccc3)cc2)c1.O=P([O-])([O-])[O-].[K+].[K+].[K+].c1ccc2c(c1)N=c1c-2ccc2c1=Nc1ccccc1-2>C1(C)C=CC=CC=1.[Pd].[Pd].C(=CC(C=CC1C=CC=CC=1)=O)C1C=CC=CC=1.C(=CC(C=CC1C=CC=CC=1)=O)C1C=CC=CC=1.C(=CC(C=CC1C=CC=CC=1)=O)C1C=CC=CC=1.C(P(C(C)(C)C)C(C)(C)C)(C)(C)C>c1ccc(-c2ccc(-c3cccc(-n4c5ccccc5c5ccc6c7ccccc7[nH]c6c54)c3)cc2)cc1 |
US09450192B2 | 2,016 | CC(=O)n1c2ccccc2c2cc(Br)ccc21.Cc1ccc(Nc2ccc(C)cc2)cc1>[Cu]=O>Cc1ccc(N(c2ccc(C)cc2)c2ccc3[nH]c4ccccc4c3c2)cc1 | CC(=O)n1c2ccccc2c2cc(Br)ccc21.Cc1ccc(Nc2ccc(C)cc2)cc1>[Cu]=O>Cc1ccc(N(c2ccc(C)cc2)c2ccc3[nH]c4ccccc4c3c2)cc1 |
US09450195B2 | 2,016 | Brc1ccc(Br)nc1.O=C([O-])[O-].OB(O)c1ccc(F)cc1F.[K+].[K+].c1ccc(P(c2ccccc2)c2ccccc2)cc1>O.C(O[Pd]OC(=O)C)(=O)C.CO.C(#N)C>Fc1ccc(-c2ccc(Br)cn2)c(F)c1 | Brc1ccc(Br)nc1.O=C([O-])[O-].OB(O)c1ccc(F)cc1F.[K+].[K+].c1ccc(P(c2ccccc2)c2ccccc2)cc1>O.C(O[Pd]OC(=O)C)(=O)C.CO.C(#N)C>Fc1ccc(-c2ccc(Br)cn2)c(F)c1 |
US09450195B2 | 2,016 | CCCCO.Cc1cc(Cl)cc(C)c1B1OC(C)(C)C(C)(C)O1.Fc1ccc(-c2ccc(Br)cn2)c(F)c1.[Li+].[OH-]>O.C(O[Pd]OC(=O)C)(=O)C.C1(P(C2CCCCC2)C2C=C(C3C(C(C)C)=CC(C(C)C)=CC=3C(C)C)C=CC=2)CCCCC1>Cc1cc(Cl)cc(C)c1-c1ccc(-c2ccc(F)cc2F)nc1 | CCCCO.Cc1cc(Cl)cc(C)c1B1OC(C)(C)C(C)(C)O1.Fc1ccc(-c2ccc(Br)cn2)c(F)c1.[Li+].[OH-]>O.C(O[Pd]OC(=O)C)(=O)C.C1(P(C2CCCCC2)C2C=C(C3C(C(C)C)=CC(C(C)C)=CC=3C(C)C)C=CC=2)CCCCC1>Cc1cc(Cl)cc(C)c1-c1ccc(-c2ccc(F)cc2F)nc1 |
US09450195B2 | 2,016 | C1COCCO1.CC(=O)[O-].CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Cc1cc(Cl)cc(C)c1-c1ccc(-c2ccc(F)cc2F)nc1.[K+]>O.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].[Pd].C1(P(C2CCCCC2)C2CCCCC2)CCCCC1>Cc1cc(B2OC(C)(C)C(C)(C)O2)cc(C)c1-c1ccc(-c2ccc(F)cc2F)nc1 | C1COCCO1.CC(=O)[O-].CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Cc1cc(Cl)cc(C)c1-c1ccc(-c2ccc(F)cc2F)nc1.[K+]>O.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].[Pd].C1(P(C2CCCCC2)C2CCCCC2)CCCCC1>Cc1cc(B2OC(C)(C)C(C)(C)O2)cc(C)c1-c1ccc(-c2ccc(F)cc2F)nc1 |
US09450195B2 | 2,016 | CC(C)c1cccc(C(C)C)c1N.O.O=C1CCC(=O)N1Br>CN(C=O)C>CC(C)c1cc(Br)cc(C(C)C)c1N | CC(C)c1cccc(C(C)C)c1N.O.O=C1CCC(=O)N1Br>CN(C=O)C>CC(C)c1cc(Br)cc(C(C)C)c1N |
US09450195B2 | 2,016 | CC(C)c1cc(Br)cc(C(C)C)c1N.COc1cccc(C#N)c1.C[Al](C)C.ClCCl>C1(C)C=CC=CC=1.CO>COc1cccc(C(=N)Nc2c(C(C)C)cc(Br)cc2C(C)C)c1 | CC(C)c1cc(Br)cc(C(C)C)c1N.COc1cccc(C#N)c1.C[Al](C)C.ClCCl>C1(C)C=CC=CC=1.CO>COc1cccc(C(=N)Nc2c(C(C)C)cc(Br)cc2C(C)C)c1 |
US09450195B2 | 2,016 | CC(C)O.COc1cccc(C(=N)Nc2c(C(C)C)cc(Br)cc2C(C)C)c1.O=C([O-])O.O=CCCl.[Na+]>O>COc1cccc(-c2nccn2-c2c(C(C)C)cc(Br)cc2C(C)C)c1 | CC(C)O.COc1cccc(C(=N)Nc2c(C(C)C)cc(Br)cc2C(C)C)c1.O=C([O-])O.O=CCCl.[Na+]>O>COc1cccc(-c2nccn2-c2c(C(C)C)cc(Br)cc2C(C)C)c1 |
US09450195B2 | 2,016 | CCOP(OCC)OCC.Cl.O=[N+]([O-])c1ccccc1-c1ccc(Br)cc1.[Na+].[OH-]>O>Brc1ccc2c(c1)[nH]c1ccccc12 | CCOP(OCC)OCC.Cl.O=[N+]([O-])c1ccccc1-c1ccc(Br)cc1.[Na+].[OH-]>O>Brc1ccc2c(c1)[nH]c1ccccc12 |
US09450195B2 | 2,016 | Brc1ccc2c(c1)[nH]c1ccccc12.Ic1ccccn1.NC1CCC(N)CC1.O=P([O-])([O-])[O-].[K+].[K+].[K+]>[Cu](I)I.O.O1CCOCC1>Brc1ccc2c3ccccc3n(-c3ccccn3)c2c1 | Brc1ccc2c(c1)[nH]c1ccccc12.Ic1ccccn1.NC1CCC(N)CC1.O=P([O-])([O-])[O-].[K+].[K+].[K+]>[Cu](I)I.O.O1CCOCC1>Brc1ccc2c3ccccc3n(-c3ccccn3)c2c1 |
US09450195B2 | 2,016 | Brc1ccc2c3ccccc3n(-c3ccccn3)c2c1.C1COCCO1.CNC1CCCCC1NC.[I-].[Na+]>O.[Cu]I>Ic1ccc2c3ccccc3n(-c3ccccn3)c2c1 | Brc1ccc2c3ccccc3n(-c3ccccn3)c2c1.C1COCCO1.CNC1CCCCC1NC.[I-].[Na+]>O.[Cu]I>Ic1ccc2c3ccccc3n(-c3ccccn3)c2c1 |
US09450195B2 | 2,016 | C1COCCO1.CC(=O)[O-].CC(C)c1cc(Br)cc(C(C)C)c1-n1ccnc1-c1cccc(Oc2ccc3c4ccccc4n(-c4ccccn4)c3c2)c1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.[K+]>[Li+].[Cl-].C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].[Pd].C1(P(C2CCCCC2)C2C=CC=CC=2C2C(C(C)C)=CC(C(C)C)=CC=2C(C)C)CCCCC1>CC(C)c1cc(B2OC(C)(C)C(C)(C)O2)cc(C(C)C)c1-n1ccnc1-c1cccc(Oc2ccc3c4ccccc4n(-c4ccccn4)c3c2)c1 | C1COCCO1.CC(=O)[O-].CC(C)c1cc(Br)cc(C(C)C)c1-n1ccnc1-c1cccc(Oc2ccc3c4ccccc4n(-c4ccccn4)c3c2)c1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.[K+]>[Li+].[Cl-].C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].[Pd].C1(P(C2CCCCC2)C2C=CC=CC=2C2C(C(C)C)=CC(C(C)C)=CC=2C(C)C)CCCCC1>CC(C)c1cc(B2OC(C)(C)C(C)(C)O2)cc(C(C)C)c1-n1ccnc1-c1cccc(Oc2ccc3c4ccccc4n(-c4ccccn4)c3c2)c1 |
US09450188B2 | 2,016 | Brc1ccc2[nH]c3ccccc3c2c1.Cc1ccccc1P(c1ccccc1C)c1ccccc1C.O=C([O-])[O-].OB(O)c1cccc2c1sc1ccccc12.[K+].[K+]>C([O-])(=O)C.[Pd+2].C([O-])(=O)C.C(O)C.C1(C)C=CC=CC=1>c1ccc2c(c1)[nH]c1ccc(-c3cccc4c3sc3ccccc34)cc12 | Brc1ccc2[nH]c3ccccc3c2c1.Cc1ccccc1P(c1ccccc1C)c1ccccc1C.O=C([O-])[O-].OB(O)c1cccc2c1sc1ccccc12.[K+].[K+]>C([O-])(=O)C.[Pd+2].C([O-])(=O)C.C(O)C.C1(C)C=CC=CC=1>c1ccc2c(c1)[nH]c1ccc(-c3cccc4c3sc3ccccc34)cc12 |
US09450188B2 | 2,016 | Brc1ccc2[nH]c3ccccc3c2c1.Cc1ccccc1P(c1ccccc1C)c1ccccc1C.O=C([O-])[O-].OB(O)c1cccc2c1oc1ccccc12.[K+].[K+]>C([O-])(=O)C.[Pd+2].C([O-])(=O)C.C(O)C.C1(C)C=CC=CC=1>c1ccc2c(c1)[nH]c1ccc(-c3cccc4c3oc3ccccc34)cc12 | Brc1ccc2[nH]c3ccccc3c2c1.Cc1ccccc1P(c1ccccc1C)c1ccccc1C.O=C([O-])[O-].OB(O)c1cccc2c1oc1ccccc12.[K+].[K+]>C([O-])(=O)C.[Pd+2].C([O-])(=O)C.C(O)C.C1(C)C=CC=CC=1>c1ccc2c(c1)[nH]c1ccc(-c3cccc4c3oc3ccccc34)cc12 |
US09450188B2 | 2,016 | CC(C)(C)P(C(C)(C)C)C(C)(C)C.CC(C)(C)[O-].Ic1ccc2c(-c3ccccc3)c3ccccc3c(-c3ccccc3)c2c1.[Na+].c1ccc2c(c1)[nH]c1ccc(-c3cccc4c3sc3ccccc34)cc12>C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].CCCCCC.C1(C)C=CC=CC=1>c1ccc(-c2c3ccccc3c(-c3ccccc3)c3cc(-n4c5ccccc5c5cc(-c6cccc7c6sc6ccccc67)ccc54)ccc23)cc1 | CC(C)(C)P(C(C)(C)C)C(C)(C)C.CC(C)(C)[O-].Ic1ccc2c(-c3ccccc3)c3ccccc3c(-c3ccccc3)c2c1.[Na+].c1ccc2c(c1)[nH]c1ccc(-c3cccc4c3sc3ccccc34)cc12>C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].CCCCCC.C1(C)C=CC=CC=1>c1ccc(-c2c3ccccc3c(-c3ccccc3)c3cc(-n4c5ccccc5c5cc(-c6cccc7c6sc6ccccc67)ccc54)ccc23)cc1 |
US09450188B2 | 2,016 | Brc1ccc(-c2c3ccccc3c(-c3ccccc3)c3ccccc23)cc1.CC(C)(C)P(C(C)(C)C)C(C)(C)C.CC(C)(C)[O-].[Na+].c1ccc2c(c1)oc1c(-c3ccc4[nH]c5ccc(-c6cccc7c6oc6ccccc67)cc5c4c3)cccc12>C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].C1(C)C=CC=CC=1.CCCCCC>c1ccc(-c2c3ccccc3c(-c3ccc(-n4c5ccc(-c6cccc7c6oc6ccccc67)cc5c5cc(-c6cccc7c6oc6ccccc67)ccc54)cc3)c3ccccc23)cc1 | Brc1ccc(-c2c3ccccc3c(-c3ccccc3)c3ccccc23)cc1.CC(C)(C)P(C(C)(C)C)C(C)(C)C.CC(C)(C)[O-].[Na+].c1ccc2c(c1)oc1c(-c3ccc4[nH]c5ccc(-c6cccc7c6oc6ccccc67)cc5c4c3)cccc12>C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].C1(C)C=CC=CC=1.CCCCCC>c1ccc(-c2c3ccccc3c(-c3ccc(-n4c5ccc(-c6cccc7c6oc6ccccc67)cc5c5cc(-c6cccc7c6oc6ccccc67)ccc54)cc3)c3ccccc23)cc1 |
US09450188B2 | 2,016 | Brc1cccc(-c2c3ccccc3c(-c3ccccc3)c3ccccc23)c1.CC(C)(C)P(C(C)(C)C)C(C)(C)C.CC(C)(C)[O-].[Na+].c1ccc2c(c1)[nH]c1ccc(-c3cccc4c3sc3ccccc34)cc12>C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].CCCCCC.C1(C)C=CC=CC=1>c1ccc(-c2c3ccccc3c(-c3cccc(-n4c5ccccc5c5cc(-c6cccc7c6sc6ccccc67)ccc54)c3)c3ccccc23)cc1 | Brc1cccc(-c2c3ccccc3c(-c3ccccc3)c3ccccc23)c1.CC(C)(C)P(C(C)(C)C)C(C)(C)C.CC(C)(C)[O-].[Na+].c1ccc2c(c1)[nH]c1ccc(-c3cccc4c3sc3ccccc34)cc12>C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].CCCCCC.C1(C)C=CC=CC=1>c1ccc(-c2c3ccccc3c(-c3cccc(-n4c5ccccc5c5cc(-c6cccc7c6sc6ccccc67)ccc54)c3)c3ccccc23)cc1 |
US09450188B2 | 2,016 | Brc1cccc(-c2c3ccccc3c(-c3ccccc3)c3ccccc23)c1.CC(C)(C)P(C(C)(C)C)C(C)(C)C.CC(C)(C)[O-].[Na+].c1ccc2c(c1)[nH]c1ccc(-c3cccc4c3oc3ccccc34)cc12>C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].CCCCCC.C1(C)C=CC=CC=1>c1ccc(-c2c3ccccc3c(-c3cccc(-n4c5ccccc5c5cc(-c6cccc7c6oc6ccccc67)ccc54)c3)c3ccccc23)cc1 | Brc1cccc(-c2c3ccccc3c(-c3ccccc3)c3ccccc23)c1.CC(C)(C)P(C(C)(C)C)C(C)(C)C.CC(C)(C)[O-].[Na+].c1ccc2c(c1)[nH]c1ccc(-c3cccc4c3oc3ccccc34)cc12>C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].CCCCCC.C1(C)C=CC=CC=1>c1ccc(-c2c3ccccc3c(-c3cccc(-n4c5ccccc5c5cc(-c6cccc7c6oc6ccccc67)ccc54)c3)c3ccccc23)cc1 |
US09450188B2 | 2,016 | Brc1ccc2[nH]c3ccccc3c2c1.Cc1ccccc1P(c1ccccc1C)c1ccccc1C.O=C([O-])[O-].OB(O)c1cccc2c1sc1c(-c3ccccc3)cccc12.[Na+].[Na+]>C([O-])(=O)C.[Pd+2].C([O-])(=O)C.C(O)C.C1(C)C=CC=CC=1>c1ccc(-c2cccc3c2sc2c(-c4ccc5[nH]c6ccccc6c5c4)cccc23)cc1 | Brc1ccc2[nH]c3ccccc3c2c1.Cc1ccccc1P(c1ccccc1C)c1ccccc1C.O=C([O-])[O-].OB(O)c1cccc2c1sc1c(-c3ccccc3)cccc12.[Na+].[Na+]>C([O-])(=O)C.[Pd+2].C([O-])(=O)C.C(O)C.C1(C)C=CC=CC=1>c1ccc(-c2cccc3c2sc2c(-c4ccc5[nH]c6ccccc6c5c4)cccc23)cc1 |
US09450188B2 | 2,016 | Brc1ccc(-c2c3ccccc3c(-c3ccccc3)c3ccccc23)cc1.CC(C)(C)P(C(C)(C)C)C(C)(C)C.CC(C)(C)[O-].[Na+].c1ccc(-c2cccc3c2sc2c(-c4ccc5[nH]c6ccccc6c5c4)cccc23)cc1>C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].CCCCCC.C1(C)C=CC=CC=1>c1ccc(-c2c3ccccc3c(-c3ccc(-n4c5ccccc5c5cc(-c6cccc7c6sc6c(-c8ccccc8)cccc67)ccc54)cc3)c3ccccc23)cc1 | Brc1ccc(-c2c3ccccc3c(-c3ccccc3)c3ccccc23)cc1.CC(C)(C)P(C(C)(C)C)C(C)(C)C.CC(C)(C)[O-].[Na+].c1ccc(-c2cccc3c2sc2c(-c4ccc5[nH]c6ccccc6c5c4)cccc23)cc1>C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].CCCCCC.C1(C)C=CC=CC=1>c1ccc(-c2c3ccccc3c(-c3ccc(-n4c5ccccc5c5cc(-c6cccc7c6sc6c(-c8ccccc8)cccc67)ccc54)cc3)c3ccccc23)cc1 |
US09450188B2 | 2,016 | Brc1ccc(-c2ccc3c(-c4ccccc4)c4ccccc4c(-c4ccccc4)c3c2)cc1.CC(C)(C)P(C(C)(C)C)C(C)(C)C.CC(C)(C)[O-].[Na+].c1ccc2c(c1)[nH]c1ccc(-c3cccc4c3sc3ccccc34)cc12>C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].CCCCCC.C1(C)C=CC=CC=1>c1ccc(-c2c3ccccc3c(-c3ccccc3)c3cc(-c4ccc(-n5c6ccccc6c6cc(-c7cccc8c7sc7ccccc78)ccc65)cc4)ccc23)cc1 | Brc1ccc(-c2ccc3c(-c4ccccc4)c4ccccc4c(-c4ccccc4)c3c2)cc1.CC(C)(C)P(C(C)(C)C)C(C)(C)C.CC(C)(C)[O-].[Na+].c1ccc2c(c1)[nH]c1ccc(-c3cccc4c3sc3ccccc34)cc12>C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].CCCCCC.C1(C)C=CC=CC=1>c1ccc(-c2c3ccccc3c(-c3ccccc3)c3cc(-c4ccc(-n5c6ccccc6c6cc(-c7cccc8c7sc7ccccc78)ccc65)cc4)ccc23)cc1 |
US09450188B2 | 2,016 | Brc1cccc(-c2ccc3c(-c4ccccc4)c4ccccc4c(-c4ccccc4)c3c2)c1.CC(C)(C)P(C(C)(C)C)C(C)(C)C.CC(C)(C)[O-].[Na+].c1ccc2c(c1)[nH]c1ccc(-c3cccc4c3sc3ccccc34)cc12>C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].CCCCCC.C1(C)C=CC=CC=1>c1ccc(-c2c3ccccc3c(-c3ccccc3)c3cc(-c4cccc(-n5c6ccccc6c6cc(-c7cccc8c7sc7ccccc78)ccc65)c4)ccc23)cc1 | Brc1cccc(-c2ccc3c(-c4ccccc4)c4ccccc4c(-c4ccccc4)c3c2)c1.CC(C)(C)P(C(C)(C)C)C(C)(C)C.CC(C)(C)[O-].[Na+].c1ccc2c(c1)[nH]c1ccc(-c3cccc4c3sc3ccccc34)cc12>C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].CCCCCC.C1(C)C=CC=CC=1>c1ccc(-c2c3ccccc3c(-c3ccccc3)c3cc(-c4cccc(-n5c6ccccc6c6cc(-c7cccc8c7sc7ccccc78)ccc65)c4)ccc23)cc1 |
US09450188B2 | 2,016 | Brc1cccc(-c2ccc3c(-c4ccccc4)c4ccccc4c(-c4ccccc4)c3c2)c1.CC(C)(C)P(C(C)(C)C)C(C)(C)C.CC(C)(C)[O-].[Na+].c1ccc2c(c1)[nH]c1ccc(-c3cccc4c3oc3ccccc34)cc12>C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].CCCCCC.C1(C)C=CC=CC=1>c1ccc(-c2c3ccccc3c(-c3ccccc3)c3cc(-c4cccc(-n5c6ccccc6c6cc(-c7cccc8c7oc7ccccc78)ccc65)c4)ccc23)cc1 | Brc1cccc(-c2ccc3c(-c4ccccc4)c4ccccc4c(-c4ccccc4)c3c2)c1.CC(C)(C)P(C(C)(C)C)C(C)(C)C.CC(C)(C)[O-].[Na+].c1ccc2c(c1)[nH]c1ccc(-c3cccc4c3oc3ccccc34)cc12>C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].CCCCCC.C1(C)C=CC=CC=1>c1ccc(-c2c3ccccc3c(-c3ccccc3)c3cc(-c4cccc(-n5c6ccccc6c6cc(-c7cccc8c7oc7ccccc78)ccc65)c4)ccc23)cc1 |