Description
This dataset contains signle site mutation of protein DLG4_RAT amino acid sequence and the correspond mutation effect score from a deep mutation scanning experiment.
Splits
traing: 1325
valid: 159
test: 176
Related paper
The dataset is from Deep generative models of genetic variation capture the effects of mutations.
Label
Label means fitness score of each mutant amino acid sequence based on a deep mutation scanning experiment. The effect of each mutation is expressed as the log frequency of observing each amino acid x at each position i in the selected versus the unselected population, relative to wild type. Ranging from negative infinity to positive infinity. If the effect larger than 0 represents high fitness, smaller than 0 represents low fitness.