<commit_before><div class="help-sub-tab">
  Most of the contents of CIViC are curator generated and edited. Below are a few examples of areas where curators are needed, culminating in a list of bite sized curation tasks that should require less than 3 minutes of your time.
  <h4>1. Adding Evidence</h4>
  <p>Evidence records are the heart of the CIViC resource. Each corresponds to evidence for a single clinical assertion about a single variant in a single cancer type. Each evidence record is based on a single citable source (e.g. a peer-reviewed publication). The evidence record consists of a free-form executive summary describing the assertion and supporting evidence for it, and additional structured fields that describe the evidence (e.g. evidence type, relevant drug, etc.). To learn more about the elements of an evidence record refer to the <a ui-sref="help.evidence" title="Evidence help">Evidence help docs</a>. For suggestions on where to find sources for evidence records, refer to the Source Ideas tab of this section. To add a new evidence record, you must login and hit the "ADD" button at the top of any page throughout the site.</p>
  <h4>2. Adding or improving Variant, Variant Group, and Gene Summaries</h4>
  <p>Once evidence sufficient evidence accumulates for a variant, variant group or gene entity, a summary should be created. The summary should be an overview of the evidence records associated with the entity. The summary should focus on the most clinically actionable evidence and should summarize for each relevant gene what a clinician should be aware of for patients with a particular variant, or variants in a particular gene. Very brief background material may be included. Additional citations beyond those associated with the evidence records can be associated directly with the summary using the "Add Source" option.</p>
  <h4>3. Editing CIViC Content</h4>
  <p>CIViC content can be edited by clicking on the pencil icon as displayed for an example Variant here:</p>
  <h4 class="edit-icon-lg">
    <div class="editableField hover">
      <span class="entity-type">VARIANT </span>
      <span class="entity-name">V600E</span>
    </div>
  </h4>
  <p>Gene, Variant, Variant Group and Evidence entities can all be edited. These edits may be expansive major updates to incorporate new evidence, error corrections, improvements to readability and style, or minor grammar and typo fixes. All such edits are welcome.</p>
  <h4>4. Comment on CIViC Content</h4>
  <p>Throughout the website are "Talk" pages where users can comment on the current contents of CIViC (specific Evidence, Variants or Genes) or on Suggested Changes. Curators are encouraged to be verbose in their comments on existing content. Critism, clarification, qualification, and questions are all appropriate. Comments from the authors of work being summarized or other with particular expertise in the area are especially desirable. When adding new evidence or summaries, comments may be used to describe the thought process of the curator. Small quotes (as allowed by the <a href="https://en.wikipedia.org/wiki/Fair_use" title="wikipedia.org Fair Use" target="_blank">Fair Use Doctrine</a>) from source publications that support a submission may also be included (but please indicate these with quotes or use the block quote style).</p>
  <h4>5. Variant attributes</h4>
  <p>In addition to variant coordinates and the variant summary, there are several other structured values associated with variant records. These include:</p>
  <ul>
    <li>Aliases. Alternative names (synonyms) for the variant. For many variants, researchers from different groups may refer to variants by different names. Multiple and varying abbreviations or identifiers exist for most variants. A variant alias is generally any name the might help CIViC users determine the various ways used to indicate the same variant.</li>
    <li>HGVS expressions</li>
    <li>Coordinates</li>
  </ul>
  <h4>6. Literature Sources</h4>
  <ul>
    <li>Primary literature</li><commit_msg>add description of variant curation task<commit_after><div class="help-sub-tab">
  Most of the contents of CIViC are curator generated and edited. Below are a few examples of areas where curators are needed, culminating in a list of bite sized curation tasks that should require less than 3 minutes of your time.
  <h4>1. Adding Evidence</h4>
  <p>Evidence records are the heart of the CIViC resource. Each corresponds to evidence for a single clinical assertion about a single variant in a single cancer type. Each evidence record is based on a single citable source (e.g. a peer-reviewed publication). The evidence record consists of a free-form executive summary describing the assertion and supporting evidence for it, and additional structured fields that describe the evidence (e.g. evidence type, relevant drug, etc.). To learn more about the elements of an evidence record refer to the <a ui-sref="help.evidence" title="Evidence help">Evidence help docs</a>. For suggestions on where to find sources for evidence records, refer to the Source Ideas tab of this section. To add a new evidence record, you must login and hit the "ADD" button at the top of any page throughout the site.</p>
  <h4>2. Adding or improving Variant, Variant Group, and Gene Summaries</h4>
  <p>Once evidence sufficient evidence accumulates for a variant, variant group or gene entity, a summary should be created. The summary should be an overview of the evidence records associated with the entity. The summary should focus on the most clinically actionable evidence and should summarize for each relevant gene what a clinician should be aware of for patients with a particular variant, or variants in a particular gene. Very brief background material may be included. Additional citations beyond those associated with the evidence records can be associated directly with the summary using the "Add Source" option.</p>
  <h4>3. Editing CIViC Content</h4>
  <p>CIViC content can be edited by clicking on the pencil icon as displayed for an example Variant here:</p>
  <h4 class="edit-icon-lg">
    <div class="editableField hover">
      <span class="entity-type">VARIANT </span>
      <span class="entity-name">V600E</span>
    </div>
  </h4>
  <p>Gene, Variant, Variant Group and Evidence entities can all be edited. These edits may be expansive major updates to incorporate new evidence, error corrections, improvements to readability and style, or minor grammar and typo fixes. All such edits are welcome.</p>
  <h4>4. Comment on CIViC Content</h4>
  <p>Throughout the website are "Talk" pages where users can comment on the current contents of CIViC (specific Evidence, Variants or Genes) or on Suggested Changes. Curators are encouraged to be verbose in their comments on existing content. Critism, clarification, qualification, and questions are all appropriate. Comments from the authors of work being summarized or other with particular expertise in the area are especially desirable. When adding new evidence or summaries, comments may be used to describe the thought process of the curator. Small quotes (as allowed by the <a href="https://en.wikipedia.org/wiki/Fair_use" title="wikipedia.org Fair Use" target="_blank">Fair Use Doctrine</a>) from source publications that support a submission may also be included (but please indicate these with quotes or use the block quote style).</p>
  <h4>5. Variant attributes</h4>
  <p>In addition to the variant summary (discussed above), there are several other structured values associated with variant records. These include:</p>
  <ul>
    <li><strong>Aliases</strong>. Alternative names (synonyms) for the variant. For many variants, researchers from different groups may refer to variants by different names. Multiple and varying abbreviations or identifiers exist for most variants. A variant alias is generally any name the might help CIViC users determine the various ways used to indicate the same variant.</li>
    <li><strong>HGVS expressions</strong>. CIViC supports and promotes variant identification using the <a href="http://varnomen.hgvs.org/" title="hgvs.org guidelines" target="_blank">Sequence Variant Nomenclature</a> guidelines of the Human Genome Variation Society (HGVS), otherwise known as 'HGVS strings'. Curators may add one or more valid HGVS values for each variant. These may be entered in protein (p.), cDNA (c.), or genomic (g.) format. A particular CIViC variant (e.g. BRAF V600E) may have multiple valid genomic alterations that could create it, each with a distinct genomic HGVS. Similarly, multiple cDNA HGVS strings may correspond to multiple transcript sequences, possibly from various transcript annotation databases (e.g. Ensembl, RefSeq, LRG, etc.).</li>
    <li><strong>Coordinates</strong>. For each variant, the goal of CIViC initially is to determine unambiguous genomic coordinates for an example instance of the variant. For example, if the paper refers to the variant as "V600E", the curator determines for a particular build of the human genome, the corresponding chromosome, start position, end position, reference base and variant base. Refer to the <a ui-sref="help.variants" target="_blank">Variants documentation</a> on the left for more details.</li>
  </ul>
  <h4>6. Literature Sources</h4>
  <ul>
    <li>Primary literature</li>
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