<commit_before><div>
	<h2 align="center">Cookies</h2>
	<p>This site uses cookies to secure the connection to Synapse. By using this website, you agree to our use of cookies. Find out more in our <a class="link" target="_blank" href="https://www.synapse.org/static/governance/SynapsePrivacyPolicy.pdf">Synapse Privacy Policy</a>.</p>
	<br/>
	<h2 align="center">Synapse Terms and Conditions of Use<br />
	  Summary of key Provisions</h2>
	<h4>Last updated: March 18, 2013</h4>
	<p>By using Synapse, you agree to the Terms and Conditions of Use listed below. Here is a summary of several key provisions of those Terms and Conditions. Be certain to read the full Terms and Conditions of Use in detail; in the event of any conflict or inconsistency between this summary and the full Terms and Conditions, the full Terms and Conditions will govern.</p>
	<p><span class="underline">When <strong>using Synapse</strong>, you must:</span></p>
	<ul class="list arrow-list">
	  <li><strong>Act ethically and responsibly</strong>.</li>
	  <li><strong>Protect and respect data participant&rsquo;s privacy and confidentiality </strong></li>
	  <li><strong>Abide by all applicable laws and regulations</strong>.</li>
	  <li><strong>Not hack Synapse</strong>.</li>
	  <li><strong>Share content only when you have authority</strong> to do so and sharing does not violate any applicable laws or contracts.</li>
	  <li>Take <strong>full responsibility</strong> for your use of data, software and other Synapse content.</li>
	</ul>
	<br/>
	<p><span class="underline">If using or contributing<strong> data</strong> on Synapse, you must:</span></p>
	<ul class="list arrow-list">
	  <li><strong>Register using accurate, current and complete information</strong>.<strong></strong></li>
	  <li><strong>Understand and respect the specific rules for redistributing dataset, software or other content</strong>.<strong></strong></li>
	  <li><strong>Respect intellectual property rights</strong> of others and <strong>acknowledge contributors</strong> in all presentations. </li>
	  <li><strong>Not discriminate,</strong> <strong>identify, or re-contact</strong> individuals or groups represented by the data.</li>
	  <li>Use and contribute only data that has been <strong>de-identified to HIPAA standards</strong>. For information about de-identification in accordance with the HIPAA Privacy Rule, please visit 
	  <a class="link" target="_blank" href="http://www.hhs.gov/ocr/privacy/hipaa/understanding/coveredentities/De-identification/guidance.html">http://www.hhs.gov/ocr/privacy/hipaa/understanding/coveredentities/De-identification/guidance.html</a>. </li>
	  <li><strong>Ensure that human participants have consented to share their data on Synapse, where required by applicable law</strong>.<strong></strong></li>
	  <li><strong>Keep personal information private and secure from any potential abuses</strong>.<strong></strong></li>
	</ul>
	<br/>
	<p><span class="underline">Sage Bionetworks wants you to know that:</span></p>
	<ul class="list arrow-list">
	  <li>Contribution to and use of data in the Synapse Commons are governed by <strong>these 
	  <a class="link" target="_blank" href="https://www.synapse.org/static/governance/SynapseCommonsDataUseProcedure.pdf">Terms and Conditions of Use</a>, 
	  the </strong><a class="link" target="_blank" href="https://www.synapse.org/static/governance/SynapseCommonsDataUseProcedure.pdf"><strong>Synapse Commons Data Use Procedure</strong></a>
	  <strong> and the </strong><a class="link" target="_blank" href="https://www.synapse.org/static/governance/SynapsePrivacyPolicy.pdf"><strong>Synapse Privacy Policy</strong></a><strong>.</strong></li>
	  <li>We will <strong>remove content</strong> if we deem it inappropriate.</li>
	  <li>These Terms and Conditions of Use apply to, but we otherwise do not monitor, data or content contributed to <strong>private workspaces</strong>.</li>
	  <li>We respect the <strong>intellectual property rights</strong> of others, and ask you to do the same.</li>
	  <li>You must be <strong>13 years old of age </strong>to use this site. </li>
	  <li>We take <strong>no responsibility or liability for any content</strong> that has been posted to Synapse.</li>
	  <li>You may <strong>cancel your Synapse account at any time</strong>.</li>
	</ul>
	<br/>


	<p align="center"><h3>Synapse Terms and Conditions of Use</h3></p>
	<p>Last updated: <strong>March 18, 2013</strong></p>
	<p><strong>&nbsp;</strong></p>
	<p>Welcome to Synapse, a service operated by Sage Bionetworks, an IRS 501(c)(3) public charity<strong> </strong>(&ldquo;<strong>Sage Bionetworks</strong>,&rdquo; &ldquo;<strong>we</strong>,&rdquo; or &ldquo;<strong>us</strong>&rdquo;). These Terms and Conditions of Use (&ldquo;<strong>Terms</strong>&rdquo;) are a binding legal agreement between you and Sage Bionetworks regarding your use of Synapse, Sage Bionetworks&rsquo; computational and storage software platform enabling collaborative, data-driven research on integrative genomic datasets, including any replacements thereof and successors thereto (&ldquo;<strong>Synapse</strong>&rdquo; or the &ldquo;<strong>Service</strong>&rdquo;). Synapse is comprised of a publicly-available portion designed to enable combined analysis of genomic data (the &ldquo;<strong>Synapse Commons</strong>&rdquo;), as well as workspaces on Synapse designated as private by a Synapse user (&ldquo;<strong>Private Workspaces</strong>&rdquo;). Unless otherwise indicated in these Terms, all references to Synapse and the Service include both the Synapse Commons and Private Workspaces.<br />
	  Please read these Terms carefully. By using Synapse, or downloading, uploading, installing, or using any genomic, molecular, phenotypic and/or other data from human or non-human sources (&ldquo;<strong>Data</strong>&rdquo;), any algorithms, tools, and other software code in source or object form (&ldquo;<strong>Software</strong>&rdquo;), or any other information and content (such content, including Software, is referred to in these Terms as &ldquo;<strong>Content</strong>&rdquo;) available on or through Synapse, you agree to be bound by this Agreement and use Synapse and all Data and Content in compliance with this Agreement. If you are using the Service on behalf of a company or other legal entity, you represent and warrant that you have the legal authority to bind such company or entity to this Agreement.<br />
	  In addition, when using certain features of Synapse, you also will be subject to the guidelines, terms, and agreements applicable to such features (&ldquo;<strong>Policies</strong>&rdquo;). For example, the <a class="link" target="_blank" href="https://www.synapse.org/static/governance/SynapsePrivacyPolicy.pdf">Synapse Privacy Policy</a> describes the personal information Sage Bionetworks collects in connection to Synapse, and how we use and disclose such information. All such Policies, including the Synapse Privacy Policy and the <a class="link" target="_blank" href="https://www.synapse.org/static/governance/SynapseCommonsDataUseProcedure.pdf">Synapse Commons Data Use Procedure</a> are incorporated by reference into these Terms. If these Terms are inconsistent with any Policy, the terms in the Policy will control to the extent of the inconsistency. <br />
	  We may periodically make changes to these Terms and will identify the date of last update. We will post the updated Terms on Synapse and will also notify registered users when they log-onto Synapse of any material changes to these Terms, so please keep your registered email address current. Changes to the Terms will be effective upon being posted on Synapse, except as set forth below. Material changes to these Terms will be effective 30 days from posting of such change or receiving notification by email (&ldquo;<strong>Effective Date</strong>&rdquo;). We encourage you to review the most recent version of the Terms frequently and remain informed of any changes to these Terms. If you continue to use Synapse after we modify these Terms, you will be deemed to have consented to terms of the modified agreement for your use of Synapse as of the date of the modification. If you do not agree to any provision of these Terms, you must not use Synapse. </p>
	<p>&nbsp;</p>
	<ol class="akl">
	  <li><strong>Eligibility</strong></li>
	</ol>
	<p>You must be 13 years of age or older to use Synapse. Use of Synapse is void where prohibited. You represent and warrant that any information you submit to the Services or otherwise to Sage Bionetworks, during registration or otherwise, is true and accurate, that you are 13 years of age or older, and that you are fully able and competent to enter into and abide by these Terms. Each account on Synapse may be used by one human, and each human may create only a single account.</p>
	<ol>
	  <li><strong>Account Registration </strong></li>
	</ol>
	<p>You must register to use certain features of Synapse. When you register, you agree to (a)&nbsp;provide accurate, current and complete information about you as may be prompted by registration forms on Synapse (&ldquo;<strong>Registration Data</strong>&rdquo;); (b)&nbsp;maintain the security of any logins, passwords, or other credentials that you select or that are provided to you for use on Synapse; and (c) maintain and promptly update the Registration Data, and any other information you provide to us, and to keep all such information accurate, current, and complete. You will notify us immediately of any unauthorized use of your account or any other breach of security by emailing us at <EMAIL>. If messages sent to an email address provided by you are returned as undeliverable, we reserve the right to terminate your account immediately with or without notice to you and without any liability to you or any third party, subject to applicable law.</p>
	<ol>
	  <li><strong>Fees; No Refunds</strong><strong> </strong></li>
	</ol>
	<p><strong>&nbsp;</strong></p>
	<p>Access to the Service presently is provided to you free of charge. Sage Bionetworks reserves the right to implement fees or change the fees for Synapse, or portions thereof, at any time by providing you notice on Synapse or otherwise. </p>
	<ol>
	  <li><strong>Access to and Use of Data and other Content</strong></li>
	</ol>
	<p><strong>&nbsp;</strong></p>
	<ol>
	  <ol>
	    <li><strong>Overview</strong></li>
	  </ol>
	</ol>
	<p>Synapse gives registered users the ability to upload and make available to other users Data and Software. Any Data or Software that is posted or transmitted by any user of Synapse other than Sage Bionetworks is referred to in these Terms as &ldquo;<strong>User Materials</strong>.&rdquo;<br />
	  Data will be made available through the Synapse Commons using a three-tier data use system, as discussed in greater detail in the <a class="link" target="_blank" href="https://www.synapse.org/static/governance/SynapseCommonsDataUseProcedure.pdf">Synapse Commons Data Use Procedure</a> and the <a class="link" target="_blank" href="https://www.synapse.org/static/governance/SynapsePrivacyPolicy.pdf">Synapse Privacy Policy</a> (collectively, the &ldquo;<strong>Synapse Commons Data Terms of Use</strong>&rdquo;). This Section 4(a) contains a brief overview of the three-tier data use systems for the Synapse Commons, but you should review the Synapse Commons Data Terms of Use carefully. In the event of any conflict or inconsistency between this Section 4(a) and the Synapse Commons Data Terms of Use, the Synapse Commons Data Terms of Use govern to the extent of the conflict or inconsistency.<br />
	  While it is Sage Bionetworks&rsquo; policy to promote Data sharing with as few restrictions as possible (Open Data) on the Synapse Commons, the Synapse Commons accommodates Data sharing under restricted conditions when required by informed consent, legal contract and/or privacy requirements as disclosed by the Data contributor (Restricted or Controlled Data). This process is designed to allow Data sharing within the legal and ethical framework for responsible use of genomic Data.</p>
	<p>-<strong> </strong><strong>Open Data (&ldquo;Tier 1&rdquo;) </strong>includes data that may be shared with every Registered Synapse user in an unrestricted manner. Users have authority to access all Open Data following agreement to these Terms and Conditions of Use. <br />
	  -<strong> </strong><strong>Restricted Data (&ldquo;Tier 2&rdquo;)</strong> includes data that may be shared only following user agreement to comply with additional data-specific terms. These terms are imposed only when required to maintain protections, regulatory or legal conditions described as part of informed consent or legal contracts enacted during the process of Data generation and disclosed by the Data contributor. <br />
	  -<strong> </strong><strong>Controlled Data (&ldquo;Tier 3&rdquo;)</strong> includes data requiring additional protections for human subjects, like sensitive information or data from &ldquo;vulnerable populations&rdquo; as defined using <a class="link" target="_blank" href="http://www.hhs.gov/ohrp/policy/index.html">OHRP guidelines</a> and by the <a class="link" target="_blank" href="http://ec.europa.eu/justice/data-protection/index_en.htm">European Data Protection Directive</a> and its implementation in applicable local law. Sharing of controlled data is considered to confer more than minimal additional risk of re-identification and/or harm to human participants and contribution or use of these data requires independent review/monitoring. <br />
	  Individuals interested in submitting Data to the Synapse Commons must comply with the Synapse Commons Data Terms of Use, including their requirement to work with Sage Bionetworks to ensure that Data is shared using the appropriate terms of use and restrictions. <br />
	  Subject to applicable law, we take no responsibility and assume no liability for any User Materials posted, stored, or uploaded by you or any third party, or for any loss or damage to any User Materials. Although we have no obligation to screen, edit, or monitor any User Materials posted on or transmitted through Synapse (other than Data posted to the Synapse Commons, to the extent described in the <a class="link" target="_blank" href="https://www.synapse.org/static/governance/SynapseCommonsDataUseProcedure.pdf">Synapse Commons Data Use Procedure</a> and the <a class="link" target="_blank" href="https://www.synapse.org/static/governance/SynapsePrivacyPolicy.pdf">Synapse Privacy Policy</a>),<strong> </strong>we reserve the right, and have discretion, to remove and screen, any User Materials posted, stored, or transmitted on or through Synapse at any time and without notice. </p>
	<p>Moreover, we provide you with the opportunity to use Private Workspaces on Synapse, and to only designate Content and Data as accessible to certain other Synapse users. We take reasonable measures in an effort to ensure that access to such Content or Data, or to any Private Workspace, by unauthorized individuals or entities will not occur, but we cannot guarantee that any such unauthorized access will not occur and make no representations or warranties in this regard. </p>
	<p>&nbsp;</p>
	<p><strong>Licensing</strong></p>
	<p><strong>Software and Data</strong></p>
	<p>Subject to applicable law, if you post or transmit any Software or Data on or through Synapse, then you grant us and our subsidiaries and affiliates a nonexclusive, royalty-free, no-charge, perpetual, irrevocable, worldwide, fully sub-licensable right and license to use, reproduce, modify, adapt, publish, translate, create derivative works from, distribute, perform, and display such User Materials throughout the world in any media (provided, however, that the preceding right and license extends only to the extent reasonably necessary for us to host such Software or Data on Synapse and to make it available on Synapse and take other actions with respect to such Data as contemplated by these Terms and Conditions of Use and the Synapse Commons Data Terms of Use). </p>
	<p>If you post or transmit any Software or Data on or through the Synapse Commons, then, subject to applicable law, unless you otherwise properly indicate other license terms or other terms and conditions, you grant us, our subsidiaries and affiliates, and all other users of the Synapse Commons a nonexclusive, royalty-free, no-charge, perpetual, irrevocable, worldwide right and license to use, reproduce, modify, adapt, publish, translate, create derivative works from, distribute, perform, and display such User Materials throughout the world in any media. </p>
	<p>If you post or transmit any Software or Data to any Private Workspace, you may grant other users of such Private Workspace such rights and licenses as you deem appropriate. </p>
	<p><strong>Other User Materials</strong></p>
	<p>If you post or transmit any User Materials other than Software, Data, and Registration Data on or through Synapse Commons, then, unless you or we indicate otherwise, subject to applicable law, you (a) grant us and our subsidiaries and affiliates a nonexclusive, royalty-free, no-charge, perpetual, irrevocable, worldwide, fully sub-licensable right and license to use, reproduce, modify, adapt, publish, translate, create derivative works from, distribute, perform, and display such User Materials throughout the world in any media; (b) grant us, our subsidiaries and affiliates, and all other users of Synapse, a nonexclusive, royalty-free, no-charge, perpetual, irrevocable, worldwide, fully sub-licensable patent license to make, have made, use, offer to sell, export, and otherwise transfer such User Materials both on and off of Synapse; and (c) grant us and our affiliates, subsidiaries, and sub-licensees the right to use the name that you submit in connection with such User Materials, if we choose, in each case subject to applicable law. </p>
	<p><strong>Synapse Commons Data Content, Access and Use Procedures</strong></p>
	<p>These Terms and Conditions of Use, the <a class="link" target="_blank" href="https://www.synapse.org/static/governance/SynapseCommonsDataUseProcedure.pdf">Synapse Commons Data Use Procedure</a> and the <a class="link" target="_blank" href="https://www.synapse.org/static/governance/SynapsePrivacyPolicy.pdf">Synapse Privacy Policy</a> govern all use of, and all contributions of, all Data to the Synapse Commons. All use of, and all contributions of, Data on the Synapse Commons must comply with these terms. </p>
	<p>Without limiting the generality of the foregoing, (a) all contributors and users of Data must take all actions described in the Synapse Commons Data Terms of Use with respect to the Data they contribute or use; and (b) your access to and use of certain types of Data may be subject to additional terms and conditions that you will be required to agree to before receiving access to such Data.</p>
	<p>Data and Content contributed to Private Workspaces are not reviewed or monitored by Synapse, but all contributions of User Materials (including, without limitation, Data) thereto must comply with these Terms.</p>
	<p><strong>Representations and Warranties</strong></p>
	<p>If you post or transmit any User Materials on or through Synapse, then you represent and warrant that (i) you own and control all of the rights to the User materials that you post or transmit, or you otherwise have the right to post such User Materials to Synapse and to specify use of such User Materials by us and by other users of Synapse; (ii) all Data is de-identified in accordance with the Health Insurance Portability and Accountability Act of 1996 and its implementing regulations, as amended (&ldquo;<strong>HIPAA</strong>&rdquo;), (iii) you have obtained any and all consents, waivers, authorizations and/or institutional or independent review board (IRB) approvals necessary to provide the Data for use on the Synapse Commons and/or Private Workspaces, as applicable, (iv) when posting or transmitting genomic Data from EU individuals and/or if required by applicable privacy laws and regulations, you have verified that specific, informed and freely given consents was obtained prior to posting or transmitting genomic Data on or through Synapse; and (v) the&nbsp;use and posting of User Materials you supply does not violate the Synapse Commons Data Use Procedure or these Terms, will not violate any rights of or cause injury to any person or entity, and will not otherwise create any harm or liability of any type for us or for third parties.</p>
	<p>All Content accessible through Synapse is for informational purposes only. Materials are not a substitute for professional advice on any matter, medical or otherwise. Always seek the advice of a qualified health professional. Sage Bionetworks does not recommend or endorse any treatment, institution, professional, physician, product, procedure or other information that may be mentioned through Synapse.</p>
	<ol>
	  <li><a name="_Ref309598989" id="_Ref309598989"><strong>API Terms</strong></a>. We may offer users the ability to access Data via an application programming interface (&ldquo;<strong>API</strong>&rdquo;). Any use of the API, including use of the API through a third-party product that accesses Synapse, is bound by these Terms and Conditions of Use plus the following specific terms:<strong> </strong></li>
	</ol>
	<p><strong>&nbsp;</strong></p>
	<ol start="5" type="1">
	  <ol start="1" type="a">
	    <li>Abuse       or excessively frequent requests to Synapse via any API (as determined by us in our sole       discretion) may result in the temporary or permanent suspension of your       account&rsquo;s access to the API. </li>
	  </ol>
	</ol>
	<ol start="5" type="1">
	  <ol start="2" type="a">
	    <li>You       must not access or use the API through any technology or means other than       those provided in Synapse or through other explicitly authorized means we       may designate. You must not hide       or mask from us your identity as it accesses Data using the API.</li>
	  </ol>
	</ol>
	<p>&nbsp;</p>
	<ol start="5" type="1">
	  <ol start="3" type="a">
	    <li>We       reserve the right at any time to modify or discontinue, temporarily or       permanently, your access to the API (or any part thereof) with or without       notice.</li>
	  </ol>
	</ol>
	<ol start="5" type="1">
	  <ol start="4" type="a">
	    <li>Without       limiting the generality of the foregoing in this Section 5 , subject to applicable law, you expressly       understand and agree that we will not be liable for any losses or direct,       indirect, incidental, special, consequential or exemplary damages,       including but not limited to damages for loss of profits, goodwill, use,       data or other intangible losses, even if we have been advised of the       possibility of such losses or damages (unless such losses were reasonably       foreseeable by us at the time you agreed to these terms), resulting from       your use of or inability to use the API, or any third-party code or       products that access data via the API. </li>
	  </ol>
	</ol>
	<p><strong>&nbsp;</strong></p>
	<ol>
	  <li><strong>Use Restrictions</strong></li>
	</ol>
	<p>In your use of Synapse, you agree not to:</p>
	<ol>
	  <ol>
	    <ol>
	      <li>Contribute any Data to Synapse that is not de-identified in accordance with the HIPAA Privacy Rule and any other applicable privacy laws and regulations (for information about de-identification in accordance with the HIPAA Privacy Rule, please visit <a class="link" target="_blank" href="http://www.hhs.gov/ocr/privacy/hipaa/understanding/coveredentities/De-identification/guidance.html">http://www.hhs.gov/ocr/privacy/hipaa/understanding/coveredentities/De-identification/guidance.html</a>); </li>
	      <li>Publish, present or otherwise disclose Data or results from analysis of Data obtained through Synapse without properly attributing the Data source using the language provided by the Data contributor of that Data set;</li>
	      <li>Redistribute Data in a manner that fails to comply with any provision of the <a class="link" target="_blank" href="https://www.synapse.org/static/governance/SynapseCommonsDataUseProcedure.pdf">Synapse Commons Data Use Procedure</a> without limiting the generality of the foregoing, &ldquo;Controlled&rdquo; (Tier 3) Data may not be redistributed, and &ldquo;Open&rdquo; (Tier 1) and &ldquo;restricted&rdquo; (Tier 2) Data may be redistributed, but solely to the extent the redistributing user assures that all subsequent recipients comply with these Terms and Conditions of Use, the Synapse Privacy Policy, as well as any additional Dataset-specific terms of use);</li>
	      <li>Make any attempt to engage in any use of Data or Content that could potentially harm, marginalize, or discriminate against individuals or populations, whether in insurance, employment, or other manners;</li>
	      <li>Identify, or make any attempt to identify, any individual humans to which any Data pertains;</li>
	      <li>Create a false identify, impersonate another person or entity in any way, or falsely imply that any third-party service is associated with Synapse;</li>
	      <li>Upload or otherwise transmit to or through Synapse any information, content, or materials that infringe, misappropriate, or violate any patent, trademark, trade secret, copyright, privacy and confidentiality rights, or other rights of any party, including by incorporating any such material in User Materials;</li>
	      <li>Upload or otherwise transmit to or through Synapse any User Materials that violate, or cause us or our affiliates to violate, any applicable law, regulation, or order of any governmental authority in any jurisdiction; </li>
	      <li>Upload or otherwise transmit to or through Synapse any unlawful, harmful, harassing, defamatory, threatening, vulgar, sexually explicit, hateful or otherwise objectionable User Materials of any kind, or any User Materials that can cause harm or delay to Synapse or computers or networks of any kind;</li>
	      <li>Upload or otherwise transmit any trade secrets or information for which you have any obligation of confidentiality or professional secrecy;</li>
	      <li>Upload or otherwise transmit any unsolicited or unauthorized advertising, promotional materials, junk mail, spam, or any other form of solicitation (commercial or otherwise);</li>
	      <li>Restrict, discourage or inhibit any person from using Synapse;</li>
	      <li>Undertake, cause, permit or authorize the modification, creation of derivative works, translation, reverse engineering, decompiling, disassembling or hacking of any aspect of Synapse or any part thereof, or attempt to do any of the foregoing, except and solely to the extent permitted by these Terms, the authorized features of Synapse, or by law, or otherwise attempt to use or access any portion of Synapse other than as intended by us;</li>
	      <li>Reproduce, distribute, publicly display, publicly perform, sell, trade, resell or exploit any portion of Synapse, use of Synapse, access to Synapse or Content obtained through Synapse, for any purpose other than expressly permitted by these Terms, including, by way of example and not limitation, by doing or engaging in any of the following without our express written consent:</li>
	      <ol>
	        <li>framing, embedding and/or passing off Data or Content obtained from Synapse in such a manner as to present it as originating from a source other than Synapse;</li>
	        <li>altering or bypassing any approved software or other mechanisms through which Synapse or any of its Data or Content is made available; and</li>
	        <li>using any trademarks, service marks, design marks, logos, photographs or other content belonging to us or obtained from Synapse.</li>
	      </ol>
	      <li>Gain unauthorized access to Synapse, to other users&rsquo; accounts, Private Workspaces, names or personally identifiable information, to any other Data or Content on Synapse, or to other computers or websites connected or linked to Synapse;</li>
	      <li>Post, transmit or otherwise make available any virus, worm, spyware or any other computer code, file or program that may or is intended to damage or hijack the operation of any hardware, software or telecommunications equipment, or any other aspect of Synapse or communications equipment and computers connected to Synapse;</li>
	      <li>Remove, disable, damage, circumvent or otherwise interfere with any security-related features of Synapse, features that prevent or restrict the use or copying of any part of Synapse or any Data or Content on Synapse, features that limit or prevent access to Private Workspaces, or features that enforce limitations on the use of Synapse or any Data or Content on Synapse;</li>
	      <li>Use any scraper, spider, robot or other automated means of any kind to access Synapse, except and solely to the extent permitted by these Terms and the features of Synapse, deep-link to any feature or any Data or Content on Synapse, bypass our robot exclusion headers or other measures we may use to prevent or restrict access to Synapse;</li>
	      <li>Use excessive bandwidth, whether through our API or otherwise, and as determined by us in our sole discretion, on the Service (if your bandwidth usage significantly exceeds the average bandwidth usage of other Synapse users, as determined by us in our sole discretion), we reserve the right to immediately disable your account or throttle your file hosting until you can reduce your bandwidth consumption);</li>
	    </ol>
	  </ol>
	</ol>
	<p>&nbsp;</p><commit_msg>SWC-3107: fix pdf links<commit_after><div>
	<h2 align="center">Cookies</h2>
	<p>This site uses cookies to secure the connection to Synapse. By using this website, you agree to our use of cookies. Find out more in our <a class="link" target="_blank" href="http://s3.amazonaws.com/static.synapse.org/governance/SynapsePrivacyPolicy.pdf">Synapse Privacy Policy</a>.</p>
	<br/>
	<h2 align="center">Synapse Terms and Conditions of Use<br />
	  Summary of key Provisions</h2>
	<h4>Last updated: March 18, 2013</h4>
	<p>By using Synapse, you agree to the Terms and Conditions of Use listed below. Here is a summary of several key provisions of those Terms and Conditions. Be certain to read the full Terms and Conditions of Use in detail; in the event of any conflict or inconsistency between this summary and the full Terms and Conditions, the full Terms and Conditions will govern.</p>
	<p><span class="underline">When <strong>using Synapse</strong>, you must:</span></p>
	<ul class="list arrow-list">
	  <li><strong>Act ethically and responsibly</strong>.</li>
	  <li><strong>Protect and respect data participant&rsquo;s privacy and confidentiality </strong></li>
	  <li><strong>Abide by all applicable laws and regulations</strong>.</li>
	  <li><strong>Not hack Synapse</strong>.</li>
	  <li><strong>Share content only when you have authority</strong> to do so and sharing does not violate any applicable laws or contracts.</li>
	  <li>Take <strong>full responsibility</strong> for your use of data, software and other Synapse content.</li>
	</ul>
	<br/>
	<p><span class="underline">If using or contributing<strong> data</strong> on Synapse, you must:</span></p>
	<ul class="list arrow-list">
	  <li><strong>Register using accurate, current and complete information</strong>.<strong></strong></li>
	  <li><strong>Understand and respect the specific rules for redistributing dataset, software or other content</strong>.<strong></strong></li>
	  <li><strong>Respect intellectual property rights</strong> of others and <strong>acknowledge contributors</strong> in all presentations. </li>
	  <li><strong>Not discriminate,</strong> <strong>identify, or re-contact</strong> individuals or groups represented by the data.</li>
	  <li>Use and contribute only data that has been <strong>de-identified to HIPAA standards</strong>. For information about de-identification in accordance with the HIPAA Privacy Rule, please visit 
	  <a class="link" target="_blank" href="http://www.hhs.gov/ocr/privacy/hipaa/understanding/coveredentities/De-identification/guidance.html">http://www.hhs.gov/ocr/privacy/hipaa/understanding/coveredentities/De-identification/guidance.html</a>. </li>
	  <li><strong>Ensure that human participants have consented to share their data on Synapse, where required by applicable law</strong>.<strong></strong></li>
	  <li><strong>Keep personal information private and secure from any potential abuses</strong>.<strong></strong></li>
	</ul>
	<br/>
	<p><span class="underline">Sage Bionetworks wants you to know that:</span></p>
	<ul class="list arrow-list">
	  <li>Contribution to and use of data in the Synapse Commons are governed by <strong>these 
	  <a class="link" target="_blank" href="http://s3.amazonaws.com/static.synapse.org/governance/SynapseCommonsDataUseProcedure.pdf">Terms and Conditions of Use</a>, 
	  the </strong><a class="link" target="_blank" href="http://s3.amazonaws.com/static.synapse.org/governance/SynapseCommonsDataUseProcedure.pdf"><strong>Synapse Commons Data Use Procedure</strong></a>
	  <strong> and the </strong><a class="link" target="_blank" href="http://s3.amazonaws.com/static.synapse.org/governance/SynapsePrivacyPolicy.pdf"><strong>Synapse Privacy Policy</strong></a><strong>.</strong></li>
	  <li>We will <strong>remove content</strong> if we deem it inappropriate.</li>
	  <li>These Terms and Conditions of Use apply to, but we otherwise do not monitor, data or content contributed to <strong>private workspaces</strong>.</li>
	  <li>We respect the <strong>intellectual property rights</strong> of others, and ask you to do the same.</li>
	  <li>You must be <strong>13 years old of age </strong>to use this site. </li>
	  <li>We take <strong>no responsibility or liability for any content</strong> that has been posted to Synapse.</li>
	  <li>You may <strong>cancel your Synapse account at any time</strong>.</li>
	</ul>
	<br/>


	<p align="center"><h3>Synapse Terms and Conditions of Use</h3></p>
	<p>Last updated: <strong>March 18, 2013</strong></p>
	<p><strong>&nbsp;</strong></p>
	<p>Welcome to Synapse, a service operated by Sage Bionetworks, an IRS 501(c)(3) public charity<strong> </strong>(&ldquo;<strong>Sage Bionetworks</strong>,&rdquo; &ldquo;<strong>we</strong>,&rdquo; or &ldquo;<strong>us</strong>&rdquo;). These Terms and Conditions of Use (&ldquo;<strong>Terms</strong>&rdquo;) are a binding legal agreement between you and Sage Bionetworks regarding your use of Synapse, Sage Bionetworks&rsquo; computational and storage software platform enabling collaborative, data-driven research on integrative genomic datasets, including any replacements thereof and successors thereto (&ldquo;<strong>Synapse</strong>&rdquo; or the &ldquo;<strong>Service</strong>&rdquo;). Synapse is comprised of a publicly-available portion designed to enable combined analysis of genomic data (the &ldquo;<strong>Synapse Commons</strong>&rdquo;), as well as workspaces on Synapse designated as private by a Synapse user (&ldquo;<strong>Private Workspaces</strong>&rdquo;). Unless otherwise indicated in these Terms, all references to Synapse and the Service include both the Synapse Commons and Private Workspaces.<br />
	  Please read these Terms carefully. By using Synapse, or downloading, uploading, installing, or using any genomic, molecular, phenotypic and/or other data from human or non-human sources (&ldquo;<strong>Data</strong>&rdquo;), any algorithms, tools, and other software code in source or object form (&ldquo;<strong>Software</strong>&rdquo;), or any other information and content (such content, including Software, is referred to in these Terms as &ldquo;<strong>Content</strong>&rdquo;) available on or through Synapse, you agree to be bound by this Agreement and use Synapse and all Data and Content in compliance with this Agreement. If you are using the Service on behalf of a company or other legal entity, you represent and warrant that you have the legal authority to bind such company or entity to this Agreement.<br />
	  In addition, when using certain features of Synapse, you also will be subject to the guidelines, terms, and agreements applicable to such features (&ldquo;<strong>Policies</strong>&rdquo;). For example, the <a class="link" target="_blank" href="http://s3.amazonaws.com/static.synapse.org/governance/SynapsePrivacyPolicy.pdf">Synapse Privacy Policy</a> describes the personal information Sage Bionetworks collects in connection to Synapse, and how we use and disclose such information. All such Policies, including the Synapse Privacy Policy and the <a class="link" target="_blank" href="http://s3.amazonaws.com/static.synapse.org/governance/SynapseCommonsDataUseProcedure.pdf">Synapse Commons Data Use Procedure</a> are incorporated by reference into these Terms. If these Terms are inconsistent with any Policy, the terms in the Policy will control to the extent of the inconsistency. <br />
	  We may periodically make changes to these Terms and will identify the date of last update. We will post the updated Terms on Synapse and will also notify registered users when they log-onto Synapse of any material changes to these Terms, so please keep your registered email address current. Changes to the Terms will be effective upon being posted on Synapse, except as set forth below. Material changes to these Terms will be effective 30 days from posting of such change or receiving notification by email (&ldquo;<strong>Effective Date</strong>&rdquo;). We encourage you to review the most recent version of the Terms frequently and remain informed of any changes to these Terms. If you continue to use Synapse after we modify these Terms, you will be deemed to have consented to terms of the modified agreement for your use of Synapse as of the date of the modification. If you do not agree to any provision of these Terms, you must not use Synapse. </p>
	<p>&nbsp;</p>
	<ol class="akl">
	  <li><strong>Eligibility</strong></li>
	</ol>
	<p>You must be 13 years of age or older to use Synapse. Use of Synapse is void where prohibited. You represent and warrant that any information you submit to the Services or otherwise to Sage Bionetworks, during registration or otherwise, is true and accurate, that you are 13 years of age or older, and that you are fully able and competent to enter into and abide by these Terms. Each account on Synapse may be used by one human, and each human may create only a single account.</p>
	<ol>
	  <li><strong>Account Registration </strong></li>
	</ol>
	<p>You must register to use certain features of Synapse. When you register, you agree to (a)&nbsp;provide accurate, current and complete information about you as may be prompted by registration forms on Synapse (&ldquo;<strong>Registration Data</strong>&rdquo;); (b)&nbsp;maintain the security of any logins, passwords, or other credentials that you select or that are provided to you for use on Synapse; and (c) maintain and promptly update the Registration Data, and any other information you provide to us, and to keep all such information accurate, current, and complete. You will notify us immediately of any unauthorized use of your account or any other breach of security by emailing us at <EMAIL>. If messages sent to an email address provided by you are returned as undeliverable, we reserve the right to terminate your account immediately with or without notice to you and without any liability to you or any third party, subject to applicable law.</p>
	<ol>
	  <li><strong>Fees; No Refunds</strong><strong> </strong></li>
	</ol>
	<p><strong>&nbsp;</strong></p>
	<p>Access to the Service presently is provided to you free of charge. Sage Bionetworks reserves the right to implement fees or change the fees for Synapse, or portions thereof, at any time by providing you notice on Synapse or otherwise. </p>
	<ol>
	  <li><strong>Access to and Use of Data and other Content</strong></li>
	</ol>
	<p><strong>&nbsp;</strong></p>
	<ol>
	  <ol>
	    <li><strong>Overview</strong></li>
	  </ol>
	</ol>
	<p>Synapse gives registered users the ability to upload and make available to other users Data and Software. Any Data or Software that is posted or transmitted by any user of Synapse other than Sage Bionetworks is referred to in these Terms as &ldquo;<strong>User Materials</strong>.&rdquo;<br />
	  Data will be made available through the Synapse Commons using a three-tier data use system, as discussed in greater detail in the <a class="link" target="_blank" href="http://s3.amazonaws.com/static.synapse.org/governance/SynapseCommonsDataUseProcedure.pdf">Synapse Commons Data Use Procedure</a> and the <a class="link" target="_blank" href="http://s3.amazonaws.com/static.synapse.org/governance/SynapsePrivacyPolicy.pdf">Synapse Privacy Policy</a> (collectively, the &ldquo;<strong>Synapse Commons Data Terms of Use</strong>&rdquo;). This Section 4(a) contains a brief overview of the three-tier data use systems for the Synapse Commons, but you should review the Synapse Commons Data Terms of Use carefully. In the event of any conflict or inconsistency between this Section 4(a) and the Synapse Commons Data Terms of Use, the Synapse Commons Data Terms of Use govern to the extent of the conflict or inconsistency.<br />
	  While it is Sage Bionetworks&rsquo; policy to promote Data sharing with as few restrictions as possible (Open Data) on the Synapse Commons, the Synapse Commons accommodates Data sharing under restricted conditions when required by informed consent, legal contract and/or privacy requirements as disclosed by the Data contributor (Restricted or Controlled Data). This process is designed to allow Data sharing within the legal and ethical framework for responsible use of genomic Data.</p>
	<p>-<strong> </strong><strong>Open Data (&ldquo;Tier 1&rdquo;) </strong>includes data that may be shared with every Registered Synapse user in an unrestricted manner. Users have authority to access all Open Data following agreement to these Terms and Conditions of Use. <br />
	  -<strong> </strong><strong>Restricted Data (&ldquo;Tier 2&rdquo;)</strong> includes data that may be shared only following user agreement to comply with additional data-specific terms. These terms are imposed only when required to maintain protections, regulatory or legal conditions described as part of informed consent or legal contracts enacted during the process of Data generation and disclosed by the Data contributor. <br />
	  -<strong> </strong><strong>Controlled Data (&ldquo;Tier 3&rdquo;)</strong> includes data requiring additional protections for human subjects, like sensitive information or data from &ldquo;vulnerable populations&rdquo; as defined using <a class="link" target="_blank" href="http://www.hhs.gov/ohrp/policy/index.html">OHRP guidelines</a> and by the <a class="link" target="_blank" href="http://ec.europa.eu/justice/data-protection/index_en.htm">European Data Protection Directive</a> and its implementation in applicable local law. Sharing of controlled data is considered to confer more than minimal additional risk of re-identification and/or harm to human participants and contribution or use of these data requires independent review/monitoring. <br />
	  Individuals interested in submitting Data to the Synapse Commons must comply with the Synapse Commons Data Terms of Use, including their requirement to work with Sage Bionetworks to ensure that Data is shared using the appropriate terms of use and restrictions. <br />
	  Subject to applicable law, we take no responsibility and assume no liability for any User Materials posted, stored, or uploaded by you or any third party, or for any loss or damage to any User Materials. Although we have no obligation to screen, edit, or monitor any User Materials posted on or transmitted through Synapse (other than Data posted to the Synapse Commons, to the extent described in the <a class="link" target="_blank" href="http://s3.amazonaws.com/static.synapse.org/governance/SynapseCommonsDataUseProcedure.pdf">Synapse Commons Data Use Procedure</a> and the <a class="link" target="_blank" href="http://s3.amazonaws.com/static.synapse.org/governance/SynapsePrivacyPolicy.pdf">Synapse Privacy Policy</a>),<strong> </strong>we reserve the right, and have discretion, to remove and screen, any User Materials posted, stored, or transmitted on or through Synapse at any time and without notice. </p>
	<p>Moreover, we provide you with the opportunity to use Private Workspaces on Synapse, and to only designate Content and Data as accessible to certain other Synapse users. We take reasonable measures in an effort to ensure that access to such Content or Data, or to any Private Workspace, by unauthorized individuals or entities will not occur, but we cannot guarantee that any such unauthorized access will not occur and make no representations or warranties in this regard. </p>
	<p>&nbsp;</p>
	<p><strong>Licensing</strong></p>
	<p><strong>Software and Data</strong></p>
	<p>Subject to applicable law, if you post or transmit any Software or Data on or through Synapse, then you grant us and our subsidiaries and affiliates a nonexclusive, royalty-free, no-charge, perpetual, irrevocable, worldwide, fully sub-licensable right and license to use, reproduce, modify, adapt, publish, translate, create derivative works from, distribute, perform, and display such User Materials throughout the world in any media (provided, however, that the preceding right and license extends only to the extent reasonably necessary for us to host such Software or Data on Synapse and to make it available on Synapse and take other actions with respect to such Data as contemplated by these Terms and Conditions of Use and the Synapse Commons Data Terms of Use). </p>
	<p>If you post or transmit any Software or Data on or through the Synapse Commons, then, subject to applicable law, unless you otherwise properly indicate other license terms or other terms and conditions, you grant us, our subsidiaries and affiliates, and all other users of the Synapse Commons a nonexclusive, royalty-free, no-charge, perpetual, irrevocable, worldwide right and license to use, reproduce, modify, adapt, publish, translate, create derivative works from, distribute, perform, and display such User Materials throughout the world in any media. </p>
	<p>If you post or transmit any Software or Data to any Private Workspace, you may grant other users of such Private Workspace such rights and licenses as you deem appropriate. </p>
	<p><strong>Other User Materials</strong></p>
	<p>If you post or transmit any User Materials other than Software, Data, and Registration Data on or through Synapse Commons, then, unless you or we indicate otherwise, subject to applicable law, you (a) grant us and our subsidiaries and affiliates a nonexclusive, royalty-free, no-charge, perpetual, irrevocable, worldwide, fully sub-licensable right and license to use, reproduce, modify, adapt, publish, translate, create derivative works from, distribute, perform, and display such User Materials throughout the world in any media; (b) grant us, our subsidiaries and affiliates, and all other users of Synapse, a nonexclusive, royalty-free, no-charge, perpetual, irrevocable, worldwide, fully sub-licensable patent license to make, have made, use, offer to sell, export, and otherwise transfer such User Materials both on and off of Synapse; and (c) grant us and our affiliates, subsidiaries, and sub-licensees the right to use the name that you submit in connection with such User Materials, if we choose, in each case subject to applicable law. </p>
	<p><strong>Synapse Commons Data Content, Access and Use Procedures</strong></p>
	<p>These Terms and Conditions of Use, the <a class="link" target="_blank" href="http://s3.amazonaws.com/static.synapse.org/governance/SynapseCommonsDataUseProcedure.pdf">Synapse Commons Data Use Procedure</a> and the <a class="link" target="_blank" href="http://s3.amazonaws.com/static.synapse.org/governance/SynapsePrivacyPolicy.pdf">Synapse Privacy Policy</a> govern all use of, and all contributions of, all Data to the Synapse Commons. All use of, and all contributions of, Data on the Synapse Commons must comply with these terms. </p>
	<p>Without limiting the generality of the foregoing, (a) all contributors and users of Data must take all actions described in the Synapse Commons Data Terms of Use with respect to the Data they contribute or use; and (b) your access to and use of certain types of Data may be subject to additional terms and conditions that you will be required to agree to before receiving access to such Data.</p>
	<p>Data and Content contributed to Private Workspaces are not reviewed or monitored by Synapse, but all contributions of User Materials (including, without limitation, Data) thereto must comply with these Terms.</p>
	<p><strong>Representations and Warranties</strong></p>
	<p>If you post or transmit any User Materials on or through Synapse, then you represent and warrant that (i) you own and control all of the rights to the User materials that you post or transmit, or you otherwise have the right to post such User Materials to Synapse and to specify use of such User Materials by us and by other users of Synapse; (ii) all Data is de-identified in accordance with the Health Insurance Portability and Accountability Act of 1996 and its implementing regulations, as amended (&ldquo;<strong>HIPAA</strong>&rdquo;), (iii) you have obtained any and all consents, waivers, authorizations and/or institutional or independent review board (IRB) approvals necessary to provide the Data for use on the Synapse Commons and/or Private Workspaces, as applicable, (iv) when posting or transmitting genomic Data from EU individuals and/or if required by applicable privacy laws and regulations, you have verified that specific, informed and freely given consents was obtained prior to posting or transmitting genomic Data on or through Synapse; and (v) the&nbsp;use and posting of User Materials you supply does not violate the Synapse Commons Data Use Procedure or these Terms, will not violate any rights of or cause injury to any person or entity, and will not otherwise create any harm or liability of any type for us or for third parties.</p>
	<p>All Content accessible through Synapse is for informational purposes only. Materials are not a substitute for professional advice on any matter, medical or otherwise. Always seek the advice of a qualified health professional. Sage Bionetworks does not recommend or endorse any treatment, institution, professional, physician, product, procedure or other information that may be mentioned through Synapse.</p>
	<ol>
	  <li><a name="_Ref309598989" id="_Ref309598989"><strong>API Terms</strong></a>. We may offer users the ability to access Data via an application programming interface (&ldquo;<strong>API</strong>&rdquo;). Any use of the API, including use of the API through a third-party product that accesses Synapse, is bound by these Terms and Conditions of Use plus the following specific terms:<strong> </strong></li>
	</ol>
	<p><strong>&nbsp;</strong></p>
	<ol start="5" type="1">
	  <ol start="1" type="a">
	    <li>Abuse       or excessively frequent requests to Synapse via any API (as determined by us in our sole       discretion) may result in the temporary or permanent suspension of your       account&rsquo;s access to the API. </li>
	  </ol>
	</ol>
	<ol start="5" type="1">
	  <ol start="2" type="a">
	    <li>You       must not access or use the API through any technology or means other than       those provided in Synapse or through other explicitly authorized means we       may designate. You must not hide       or mask from us your identity as it accesses Data using the API.</li>
	  </ol>
	</ol>
	<p>&nbsp;</p>
	<ol start="5" type="1">
	  <ol start="3" type="a">
	    <li>We       reserve the right at any time to modify or discontinue, temporarily or       permanently, your access to the API (or any part thereof) with or without       notice.</li>
	  </ol>
	</ol>
	<ol start="5" type="1">
	  <ol start="4" type="a">
	    <li>Without       limiting the generality of the foregoing in this Section 5 , subject to applicable law, you expressly       understand and agree that we will not be liable for any losses or direct,       indirect, incidental, special, consequential or exemplary damages,       including but not limited to damages for loss of profits, goodwill, use,       data or other intangible losses, even if we have been advised of the       possibility of such losses or damages (unless such losses were reasonably       foreseeable by us at the time you agreed to these terms), resulting from       your use of or inability to use the API, or any third-party code or       products that access data via the API. </li>
	  </ol>
	</ol>
	<p><strong>&nbsp;</strong></p>
	<ol>
	  <li><strong>Use Restrictions</strong></li>
	</ol>
	<p>In your use of Synapse, you agree not to:</p>
	<ol>
	  <ol>
	    <ol>
	      <li>Contribute any Data to Synapse that is not de-identified in accordance with the HIPAA Privacy Rule and any other applicable privacy laws and regulations (for information about de-identification in accordance with the HIPAA Privacy Rule, please visit <a class="link" target="_blank" href="http://www.hhs.gov/ocr/privacy/hipaa/understanding/coveredentities/De-identification/guidance.html">http://www.hhs.gov/ocr/privacy/hipaa/understanding/coveredentities/De-identification/guidance.html</a>); </li>
	      <li>Publish, present or otherwise disclose Data or results from analysis of Data obtained through Synapse without properly attributing the Data source using the language provided by the Data contributor of that Data set;</li>
	      <li>Redistribute Data in a manner that fails to comply with any provision of the <a class="link" target="_blank" href="http://s3.amazonaws.com/static.synapse.org/governance/SynapseCommonsDataUseProcedure.pdf">Synapse Commons Data Use Procedure</a> without limiting the generality of the foregoing, &ldquo;Controlled&rdquo; (Tier 3) Data may not be redistributed, and &ldquo;Open&rdquo; (Tier 1) and &ldquo;restricted&rdquo; (Tier 2) Data may be redistributed, but solely to the extent the redistributing user assures that all subsequent recipients comply with these Terms and Conditions of Use, the Synapse Privacy Policy, as well as any additional Dataset-specific terms of use);</li>
	      <li>Make any attempt to engage in any use of Data or Content that could potentially harm, marginalize, or discriminate against individuals or populations, whether in insurance, employment, or other manners;</li>
	      <li>Identify, or make any attempt to identify, any individual humans to which any Data pertains;</li>
	      <li>Create a false identify, impersonate another person or entity in any way, or falsely imply that any third-party service is associated with Synapse;</li>
	      <li>Upload or otherwise transmit to or through Synapse any information, content, or materials that infringe, misappropriate, or violate any patent, trademark, trade secret, copyright, privacy and confidentiality rights, or other rights of any party, including by incorporating any such material in User Materials;</li>
	      <li>Upload or otherwise transmit to or through Synapse any User Materials that violate, or cause us or our affiliates to violate, any applicable law, regulation, or order of any governmental authority in any jurisdiction; </li>
	      <li>Upload or otherwise transmit to or through Synapse any unlawful, harmful, harassing, defamatory, threatening, vulgar, sexually explicit, hateful or otherwise objectionable User Materials of any kind, or any User Materials that can cause harm or delay to Synapse or computers or networks of any kind;</li>
	      <li>Upload or otherwise transmit any trade secrets or information for which you have any obligation of confidentiality or professional secrecy;</li>
	      <li>Upload or otherwise transmit any unsolicited or unauthorized advertising, promotional materials, junk mail, spam, or any other form of solicitation (commercial or otherwise);</li>
	      <li>Restrict, discourage or inhibit any person from using Synapse;</li>
	      <li>Undertake, cause, permit or authorize the modification, creation of derivative works, translation, reverse engineering, decompiling, disassembling or hacking of any aspect of Synapse or any part thereof, or attempt to do any of the foregoing, except and solely to the extent permitted by these Terms, the authorized features of Synapse, or by law, or otherwise attempt to use or access any portion of Synapse other than as intended by us;</li>
	      <li>Reproduce, distribute, publicly display, publicly perform, sell, trade, resell or exploit any portion of Synapse, use of Synapse, access to Synapse or Content obtained through Synapse, for any purpose other than expressly permitted by these Terms, including, by way of example and not limitation, by doing or engaging in any of the following without our express written consent:</li>
	      <ol>
	        <li>framing, embedding and/or passing off Data or Content obtained from Synapse in such a manner as to present it as originating from a source other than Synapse;</li>
	        <li>altering or bypassing any approved software or other mechanisms through which Synapse or any of its Data or Content is made available; and</li>
	        <li>using any trademarks, service marks, design marks, logos, photographs or other content belonging to us or obtained from Synapse.</li>
	      </ol>
	      <li>Gain unauthorized access to Synapse, to other users&rsquo; accounts, Private Workspaces, names or personally identifiable information, to any other Data or Content on Synapse, or to other computers or websites connected or linked to Synapse;</li>
	      <li>Post, transmit or otherwise make available any virus, worm, spyware or any other computer code, file or program that may or is intended to damage or hijack the operation of any hardware, software or telecommunications equipment, or any other aspect of Synapse or communications equipment and computers connected to Synapse;</li>
	      <li>Remove, disable, damage, circumvent or otherwise interfere with any security-related features of Synapse, features that prevent or restrict the use or copying of any part of Synapse or any Data or Content on Synapse, features that limit or prevent access to Private Workspaces, or features that enforce limitations on the use of Synapse or any Data or Content on Synapse;</li>
	      <li>Use any scraper, spider, robot or other automated means of any kind to access Synapse, except and solely to the extent permitted by these Terms and the features of Synapse, deep-link to any feature or any Data or Content on Synapse, bypass our robot exclusion headers or other measures we may use to prevent or restrict access to Synapse;</li>
	      <li>Use excessive bandwidth, whether through our API or otherwise, and as determined by us in our sole discretion, on the Service (if your bandwidth usage significantly exceeds the average bandwidth usage of other Synapse users, as determined by us in our sole discretion), we reserve the right to immediately disable your account or throttle your file hosting until you can reduce your bandwidth consumption);</li>
	    </ol>
	  </ol>
	</ol>
	<p>&nbsp;</p>
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