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											<li class="current"><a href="#">Tacrolimus</a></li>
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									<h2>Tacrolimus</h2>
									<p>[tak-row-lim-us]</p>
                                    <h4>BRAND NAMES: PROGRAF®, ADVAGRAF®</h4>
								</header>
                                <section>
                                    Tacrolimus is available in the following formulations:
                                    <ul>
                                        <li>• Tacrolimus oral suspension (prepared by transplant pharmacy)</li> 
                                        <li>• Tacrolimus EXTENDED release (ADVAgraf®), a once a day capsule</li>
                                        <li>• Tacrolimus IMMEDIATE release (PROgraf®), a twice daily capsule
                                    </ul>
                                </section>
                                <section>
                                    <h3>What is this medication for?</h3>
									<p>
										Tacrolimus is a medication used to lower your body’s immune system to prevent your transplanted organ from being rejected. It makes your white blood cells weaker so they cannot damage the new organ. 
									</p>
								</section>
                                    </div>
                                    <div class="6u 12u(mobile)">
                                <section style="float:right;">
                                    <ul>
                                        <li><b>Tacrolimus EXTENDED release (ADVAgraf®):</b><br><img class="image" src="../../images/medication-images/tacrolimus/advagraf.jpg" alt="" style="width:100%; margin:0.5em;"></li>
                                        <li><b>Tacrolimus IMMEDIATE release (PROgraf®):</b><br><img class="image" src="../../images/medication-images/tacrolimus/prograf.jpg" alt="" style="width:100%; margin:0.5em;"></li>
                                          
                                    </ul>
                                </section>
                                    </div>
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                                <div class="row">
								<section>
                                    <h3>How should I take this medication? </h3>
									<p><img class="image" src="../../images/take-with-food.png" alt="" width="20%" style="float:left;">
                                        
										Tacrolimus should be taken <b>with food</b> to decrease stomach upset, but may be taken on an empty stomach if preferred. Be consistent, if you take it with food, always take it with food; if you take it on an empty stomach, always take it on an empty stomach.<br><br>
                                        Do not take calcium supplements or antacids (Diovol®, Maalox®, etc.) within 2 hours of tacrolimus as antacids may decrease the absorption of the medication by the body. You may take tacrolimus at the same time with stomach acid reducing medications (e.g. ranitidine (Zantac®), pantoprazole (Tecta®) etc.).<br><br>
                                        When having tacrolimus blood levels drawn, do not take the morning dose of medication until after your blood sample is taken.
                                      <img src="../../images/no-grapefruit.png" alt="" style="width:15%; float:right;">  
									</p>
                                    
                                    <h4>Avoid grapefruit or grapefruit juice while on this medication due to a serious interaction.</h4>
								</section>
                                </div>
                                    <h3>What are some possible side effects of this medication? </h3>
                                
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                                          <h3>Tremor, shakiness, headache, seizures</h3>
                                        <p>Presence of these side effects may be a sign of high tacrolimus levels. Report these symptoms to your doctor. These side effects will go away when your doctor adjusts the dose.</p>
                                          <img class="image" src="../../images/headaches.png" alt="" style="float:right; width:15%;">
                                        </div>
                                      <div class="panel">
                                          <img class="image" src="../../images/blood-pressure.png" alt="" style="float:left; margin:1em; width:20%;">
                                          <h3>High blood pressure</h3>
                                        <p>Check your blood pressure regularly. Avoid foods high in salt or sodium.</p>
                                          <img class="image" src="../../images/no-salt.png" alt="" style="float:right; width:15%;">
                                        </div>
                                      <div class="panel">
                                          <img class="image" src="../../images/blood-sugar.png" alt="" style="float:left; margin:1em; width:20%;">
                                          <h3>High blood sugar</h3>
                                        <p>If you are diabetic, make sure you monitor your sugars regularly. Report any numbness or tingling in your hands or feet, increased thirst, dry mouth, fruity odour on your breath, or increased urinary frequency to your doctor.</p>
                                        </div>
                                      <div class="panel">
                                          <img class="image" src="../../images/heartburn.png" alt="" style="float:left; margin:1em; width:15%;">
                                          <h3>Heartburn, nausea, vomiting</h3>
                                          <p>Check with your doctor if any of these are bothersome or persistent.</p>
                                          <img class="image" src="../../images/vomitting.png" alt="" style="float:right; width:15%;">
                                        </div>
                                        <div class="panel">
                                            <img class="image" src="../../images/confusion.png" alt="" style="float:left; width:15%;">
                                            <h3>Mood changes, depression, confusion, difficulty sleeping, abnormal dreams</h3>
                                            <p>Check with your doctor if any of these are bothersome or persistent.</p>
                                            <img class="image" src="../../images/depression.png" alt="" style="float:right; width:15%;">
                                        </div>
                                      <div class="panel">
                                          <img class="image" src="../../images/hair-loss.png" alt="" style="float:left; margin:1em; width:20%;">
                                          <h3>Thinning or loss of hair</h3>
                                          <p>Report these symptoms to your doctor.</p>
                                        </div>
                                        <div class="panel">
                                            <img class="image" src="../../images/injury.png" alt="" style="float:left; width:15%;">
                                            <h3>Your body's ability to handle illness or injury is weakened by tacrolimus</h3>
                                            <p>Check with your doctor if you have an infection, illness or injury or are experiencing fever, chills, sore throat or other symptoms of a cold or flu.</p>
                                            <img class="image" src="../../images/cough.png" alt="" style="float:right; width:15%;">
                                        </div>
                                      <div class="panel">
                                          <img class="image" src="../../images/decrease_kidney.png" alt="" style="float:left; margin:1em; width:20%;">
                                          <h3>Decrease in kidney function</h3>
                                          <p>High tacrolimus levels may decrease your kidney function. Notify your doctor if you notice any changes in your urine or the amount produced.</p>
                                        </div>
                                      <div class="panel">
                                          <h3>Cancer</h3>
                                          <p>Taking this medication may increase your risk of skin and other cancers. Please inform your transplant team if you are diagnosed with cancer. For additional information please see section on “Cancer Risk”.</p>
                                        </div>
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                                        <span id="disclaimer">The information on this website is intended to supplement the advice given to you by your transplant team. There may be side effects or instructions that are not listed on this website. If you feel you need more information, please contact your transplant physician or clinical pharmacist.</span>
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											<li class="current"><a href="#">Tacrolimus</a></li>
											<li><a href="/anti-rejection-medication/mycophenolate">Mycophenolate</a></li>
											<li><a href="/anti-rejection-medication/azathioprine">Azathioprine</a></li>
                                            <li><a href="/anti-rejection-medication/cyclosprine">Cyclosprine</a></li>
                                            <li><a href="/anti-rejection-medication/prednisone">Prednisone</a></li>
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								<header>
									<h2>Tacrolimus</h2>
									<p>[tak-row-lim-us]</p>
                                    <h4>BRAND NAMES: PROGRAF®, ADVAGRAF®</h4>
								</header>
                                <section>
                                    Tacrolimus is available in the following formulations:
                                    <ul>
                                        <li>• Tacrolimus oral suspension (prepared by transplant pharmacy)</li> 
                                        <li>• Tacrolimus EXTENDED release (ADVAgraf®), a once a day capsule</li>
                                        <li>• Tacrolimus IMMEDIATE release (PROgraf®), a twice daily capsule
                                    </ul>
                                </section>
                                <section>
                                    <h3>What is this medication for?</h3>
									<p>
										Tacrolimus is a medication used to lower your body’s immune system to prevent your transplanted organ from being rejected. It makes your white blood cells weaker so they cannot damage the new organ. 
									</p>
								</section>
                                    </div>
                                    <div class="6u 12u(mobile)">
                                <section style="float:right;">
                                    <ul>
                                        <li><b>Tacrolimus EXTENDED release (ADVAgraf®):</b><br><img class="image" src="../../images/medication-images/tacrolimus/advagraf.jpg" alt="" style="width:100%; margin:0.5em;"></li>
                                        <li><b>Tacrolimus IMMEDIATE release (PROgraf®):</b><br><img class="image" src="../../images/medication-images/tacrolimus/prograf.jpg" alt="" style="width:100%; margin:0.5em;"></li>
                                          
                                    </ul>
                                </section>
                                    </div>
                                </div>
                                <div class="row">
								<section>
                                    <h3>How should I take this medication? </h3>
									<p><img class="image" src="../../images/take-with-food.png" alt="" width="20%" style="float:left;">
                                        
										Tacrolimus should be taken <b>with food</b> to decrease stomach upset, but may be taken on an empty stomach if preferred. Be consistent, if you take it with food, always take it with food; if you take it on an empty stomach, always take it on an empty stomach.<br><br>
                                        Do not take calcium supplements or antacids (Diovol®, Maalox®, etc.) within 2 hours of tacrolimus as antacids may decrease the absorption of the medication by the body. You may take tacrolimus at the same time with stomach acid reducing medications (e.g. ranitidine (Zantac®), pantoprazole (Tecta®) etc.).<br><br>
                                        When having tacrolimus blood levels drawn, do not take the morning dose of medication until after your blood sample is taken.
                                      <img src="../../images/no-grapefruit.png" alt="" style="width:15%; float:right;">  
									</p>
                                    
                                    <h4>Avoid grapefruit or grapefruit juice while on this medication due to a serious interaction.</h4>
								</section>
                                </div>
                                    <h3>What are some possible side effects of this medication? </h3>
                                
                                <section class="slider">     
                                    <div id="printOption" class="printOption">
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                                      <div class="panel">
                                          <img class="image" src="../../images/shakiness.png" alt="" style="float:left; margin:1em; width:20%;">
                                          <h3>Tremor, shakiness, headache, seizures</h3>
                                        <p>Presence of these side effects may be a sign of high tacrolimus levels. Report these symptoms to your doctor. These side effects will go away when your doctor adjusts the dose.</p>
                                          <img class="image" src="../../images/headaches.png" alt="" style="float:right; width:15%;">
                                        </div>
                                      <div class="panel">
                                          <img class="image" src="../../images/blood-pressure.png" alt="" style="float:left; margin:1em; width:20%;">
                                          <h3>High blood pressure</h3>
                                        <p>Check your blood pressure regularly. Avoid foods high in salt or sodium.</p>
                                          <img class="image" src="../../images/no-salt.png" alt="" style="float:right; width:15%;">
                                        </div>
                                      <div class="panel">
                                          <img class="image" src="../../images/blood-sugar.png" alt="" style="float:left; margin:1em; width:20%;">
                                          <h3>High blood sugar</h3>
                                        <p>If you are diabetic, make sure you monitor your sugars regularly. Report any numbness or tingling in your hands or feet, increased thirst, dry mouth, fruity odour on your breath, or increased urinary frequency to your doctor.</p>
                                        </div>
                                      <div class="panel">
                                          <img class="image" src="../../images/heartburn.png" alt="" style="float:left; margin:1em; width:15%;">
                                          <h3>Heartburn, nausea, vomiting</h3>
                                          <p>Check with your doctor if any of these are bothersome or persistent.</p>
                                          <img class="image" src="../../images/vomitting.png" alt="" style="float:right; width:15%;">
                                        </div>
                                        <div class="panel">
                                            <img class="image" src="../../images/confusion.png" alt="" style="float:left; width:15%;">
                                            <h3>Mood changes, depression, confusion, difficulty sleeping, abnormal dreams</h3>
                                            <p>Check with your doctor if any of these are bothersome or persistent.</p>
                                            <img class="image" src="../../images/depression.png" alt="" style="float:right; width:15%;">
                                        </div>
                                      <div class="panel">
                                          <img class="image" src="../../images/hair-loss.png" alt="" style="float:left; margin:1em; width:20%;">
                                          <h3>Thinning or loss of hair</h3>
                                          <p>Report these symptoms to your doctor.</p>
                                        </div>
                                        <div class="panel">
                                            <img class="image" src="../../images/injury.png" alt="" style="float:left; width:15%;">
                                            <h3>Your body's ability to handle illness or injury is weakened by tacrolimus</h3>
                                            <p>Check with your doctor if you have an infection, illness or injury or are experiencing fever, chills, sore throat or other symptoms of a cold or flu.</p>
                                            <img class="image" src="../../images/cough.png" alt="" style="float:right; width:15%;">
                                        </div>
                                      <div class="panel">
                                          <img class="image" src="../../images/decrease_kidney.png" alt="" style="float:left; margin:1em; width:20%;">
                                          <h3>Decrease in kidney function</h3>
                                          <p>High tacrolimus levels may decrease your kidney function. Notify your doctor if you notice any changes in your urine or the amount produced.</p>
                                        </div>
                                      <div class="panel">
                                          <h3>Cancer</h3>
                                          <p>Taking this medication may increase your risk of skin and other cancers. Please inform your transplant team if you are diagnosed with cancer. For additional information please see section on “Cancer Risk”.</p>
                                        </div>
                                    </div>
                                        </div>
								</section>
                                
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										</ul><br>
                                        <span id="disclaimer">The information on this website is intended to supplement the advice given to you by your transplant team. There may be side effects or instructions that are not listed on this website. If you feel you need more information, please contact your transplant physician or clinical pharmacist.</span>
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