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ุจุณู… ุงู„ู„ู‡ ุงู„ุฑุญู…ู† ุงู„ุฑุญูŠู…ุŒ ุงู„ุญู…ุฏ ู„ู„ู‡ ุฑุจ ุงู„ุนุงู„ู…ูŠู†ุŒ
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ูˆุฃุตู„ูŠ ูˆุฃุณู„ู… ุนู„ู‰ ุญุจูŠุจู†ุง ูˆู‚ุฑุฉ ุฃุนูŠู†ู†ุง ุณูŠุฏู†ุง ู…ุญู…ุฏ
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ุตู„ู‰ ุงู„ู„ู‡ ุนู„ูŠู‡ ูˆุณู„ู… ูˆุนู„ู‰ ุขู„ู‡ ูˆุตุญุงุจู‡ ูˆุงู„ุชุงุจุนูŠู†
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ุงู„ุณู„ุงู… ุนู„ูŠูƒู… ูˆุฑุญู…ุฉ ุงู„ู„ู‡ ูˆุจุฑูƒุงุชู‡ ููŠ ู‡ุฐู‡ ุงู„ู…ุญุงุถุฑุฉ
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ุณู†ุณุชูƒู…ู„ Metabolism and elimination of drugs from
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the eye
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ูƒู…ุง ู†ุนุฑู ุฃู† ุงู„ุฃุฏูˆูŠุฉ ุชุชุนู„ู‚ ุจุงู„ุฏุฎูˆู„ุŒ ู‡ู… ุฅู…ุง
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ุงู„ู„ูŠุจูˆููŠู„ูŠูƒ ุฃูˆ ุงู„ู‡ูŠุฏุฑูˆููŠู„ูŠูƒุŒ ู…ุซู„ ุงู„ู„ูŠุจูˆููŠู„ูŠูƒ
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ูƒู„ูˆุฑุงู†ููŠู†ูŠูƒูˆู†
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ุจุณูŠุทุฉ ุจุตูˆุฑุฉ ูƒุจูŠุฑุฉ ุจุณูŠุทุฉ ุจุตูˆุฑุฉ ูƒุจูŠุฑุฉ ุจุณูŠุทุฉ ุจุตูˆุฑุฉ
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ูƒุจูŠุฑุฉ ุจุณูŠุทุฉ ุจุตูˆุฑุฉ ูƒุจูŠุฑุฉ ุจุณูŠุทุฉ ุจุตูˆุฑุฉ ูƒุจูŠุฑุฉ ุจุณูŠุทุฉ
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ุจุตูˆุฑุฉ ูƒุจูŠุฑุฉ ุจุณูŠุทุฉ ุจุตูˆุฑุฉ ูƒุจูŠุฑุฉ ุจุณูŠุทุฉ ุจุตูˆุฑุฉ ูƒุจูŠุฑุฉ
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ุจุณูŠุทุฉ ุจุตูˆุฑุฉ ูƒุจูŠุฑุฉ ุจุณูŠุทุฉ ุจุตูˆุฑุฉ ูƒุจูŠุฑุฉ ุจุณูŠุทุฉ ุจุตูˆุฑุฉ
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ูƒุจูŠุฑุฉ ุจุณูŠุทุฉ ุจุตูˆุฑุฉ ูƒุจูŠุฑุฉ ุจุณูŠุทุฉ ุจุตูˆุฑุฉ ูƒุจูŠุฑุฉ ุจุณูŠุทุฉ
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ุจุตูˆุฑุฉ ูƒุจูŠุฑุฉ ุจุณูŠุทุฉ ุจุตูˆุฑุฉ ูƒุจูŠุฑุฉ ุจุณูŠุทุฉ ุจุตูˆุฑุฉ ูƒุจูŠุฑุฉ
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ุจุณูŠุทุฉ ุจุตูˆุฑุฉ ูƒุจูŠุฑุฉ ุจุณูŠุทุฉ ุจุตูˆุฑุฉ ูƒุจูŠุฑุฉ ุจุณูŠุทุฉ
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ุจุณุฑุนุฉ ูˆุนุงู„ูŠุฉ ุฏุงุฎู„ ุงู„ู€ aqueous flow ู‡ูˆ the
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constant flow of aqueous from ciliary processes ู…ู†
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ุงู„ุฎู„ู where it is secreted through the posterior
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chamber, pupil and anterior chamber and out of the
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eye via Schlemmโ€™s canal prevents the accumulation
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of high concentrations of antibacterial
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ูƒู„ู†ุง ู†ุนุฑู ุฃู†ู‡ ููŠ ุงู„ู…ุชูˆุณุท every 45 minutes the whole
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aqueous chamber is turned over and replaced by new
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aqueous from the ciliary processes
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ู…ุง ูŠู…ู†ุน ุจู‚ุงุก ุชุฑูƒูŠุฒ ุงู„ู€ antibiotic inside the
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aqueous humor for a long time ุนุดุงู† ู…ุง ูŠุตูŠุฑ ู…ู…ู†ูˆุน
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ุฃู†ู‡ ูŠุจู‚ู‰ ุงู„ู€ antibiotic ู…ุฑูƒุฒู‹ุง ููŠ ุงู„ู€ aqueous ู„ู…ุฏุฉ
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ุทูˆูŠู„ุฉ ู‡ูˆ
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ุงู„ุฏูˆุฑ ู‡ูˆ ุงู„ุฏูˆุฑ ู‡ูˆ ูŠุฏุฎู„ ูˆ ูŠุฒูŠู„ ุงู„ู€ antibiotic ู„ูƒู†ู‡
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ู…ูุถู„ ูŠุญุงูุธ ุนู„ู‰ peak
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ุฃุจุฏู‹ุง ู…ุด ู‡ูŠูƒุŒ ุนุดุงู† ู†ุฑุงู‚ุจ ูŠุนู†ูŠ ูƒู„ .. ุจู„ ุงู„ู€ antibody
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ู…ุซู„ู‹ุง ู‡ู†ุง ูˆุตู„ ูƒุฏู‡ุŒ ู†ุฑุงู‚ุจ ูˆ ุจุฑุฏ ู†ู†ุฒู„ู‡ุŒ ู„ูˆ ู‡ุชุฑูƒุจ ุฃู†ุช ูˆ
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ุชุทู„ุน ูู‡ูŠ ู‚ุฏ ุชุทู„ุนู„ูˆ ู…ุญุทู†ุงุด ุจู†ุฒู„ุŒ ู„ูˆ ุชุฎุฑู‚ุŒ ุจู†ุฒู„ุŒ ู„ูˆ
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ุญุทูŠู†ุง ูƒู…ุงู† ู‚ุทุฑุฉุŒ ุจุชุทู„ุน ู‡ูŠูƒุŒ ูˆู‡ุง ูƒุฏู‡ุŒ ู…ุฌุฏุด ุงู„ูˆู‚ุช
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ูŠุญุงูุธ ุนู„ู‰ ุงู„ู€ peakุŒ ู„ุฃู†ู‡ ููŠู‡ ุนุงู…ู„ turn overุŒ ุฅุฎุฑุงุฌุŒ
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ุงู„ุฏูˆุงุก ุจูŠุงุฎุฏ ู…ุน ุงู„ู€ aqueous ุนู„ู‰ ุจุฑุฉุŒ ุนู„ู‰ ุงู„ุฏู…ุŒ ูˆุงุถุญุŸ
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ุฅูŠุด ุงู„ู…ูˆุถูˆุน turn overุŸ ู„ุฐู„ูƒ ุฅุญู†ุง ุจู†ุญุงูˆู„ ู†ุญุงูุธ ุนู„ู‰
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ุฃู†ู‘ ุงู„ุฏูˆุงุก ูŠูุถู„ ุนู„ู‰ ุงู„ู€ peakุŒ ุจุฏู†ุง ู†ูุถู„ ูƒู„ every
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one hour ุฃูˆ two hours
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ุนุดุงู† ุฃู†ุง ุงุญุงูุธ ุนู„ู‰ peak ู‡ูŠูƒ stationary ุจูŠู‚ุถู„ every
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hour ุญุท ู„ู‡ ุนุดุงู† ุฃุบู„ุจ ุงู„ู…ูˆุถูˆุน turnover of drugs
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ูƒูˆูŠุณุŸ ูŠุนู†ูŠ ุนุดุงู† ู‡ูŠูƒ ุญุฏู‘ุซ ูƒู„ู‡ ูŠุนู†ูŠ ุชุฎูŠู„ ุฃู… ุฅู„ู‰
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ุงู„ุทุจูŠุจ ุชู‚ูˆู„ ูˆุงู„ู„ู‡ ุฃุนุทูˆู†ูŠ ู‚ุทุฑุฉ ู…ุซู„ู‹ุง ูƒู„ู‡ุง ููŠ ุงู„ู€ ูƒู„
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ุตุจุงุญู‹ุง ูˆู…ุซู„ู‹ุง ูˆู…ุงุฏูŠุด ู†ุชูŠุฌุฉุŒ ู…ุงุฑูŠูˆ ู‚ู„ุช ู„ู‡ ุตุญ
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ู…ุง ุจูŠุฌูŠ ู„ู‡ ู†ุชูŠุฌุฉุŒ ุงู„ู…ูุฑูˆุถ ุฃู† ุชู‚ูˆู… ุจุนู…ู„ู‡ ู…ุฑุชูŠู†
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ููŠ ุงู„ูŠูˆู…ุŒ ู…ุฑุชูŠู† ููŠ ุงู„ูŠูˆู…ุŒ ู…ุฑุชูŠู† ููŠ ุงู„ูŠูˆู…ุŒ ู…ุฑุชูŠู† ููŠ
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ุงู„ูŠูˆู…ุŒ ู…ุฑุชูŠู† ููŠ ุงู„ูŠูˆู…ุŒ ู…ุฑุชูŠู† ููŠ ุงู„ูŠูˆู…ุŒ ู…ุฑุชูŠู† ููŠ
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ุงู„ูŠูˆู…ุŒ ู…ุฑุชูŠู† ููŠ ุงู„ูŠูˆู…ุŒ ู…ุฑุชูŠู† ููŠ ุงู„ูŠูˆู…ุŒ ู…ุฑุชูŠู† ููŠ
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ุงู„ูŠูˆู…ุŒ ู…ุฑุชูŠู† ููŠ ุงู„ูŠูˆู…ุŒ ู…ุฑุชูŠู† ููŠ ุงู„ูŠูˆู…ุŒ ู…ุฑุชูŠู† ููŠ
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ุงู„ูŠูˆู…ุŒ ู…ุฑุชูŠู† ููŠ ุงู„ูŠูˆู…ุŒ ู…ุฑุชูŠู† ููŠ ุงู„ูŠูˆู…ุŒ ู…ุฑุชูŠู† ููŠ
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ุงู„ูŠูˆู…ุŒ ู…ุฑุชูŠู† ููŠ ุงู„ูŠูˆู…ุŒ ู…ุฑุชูŠู† ููŠ ุงู„ูŠูˆู…ุŒ ู…ุฑุชูŠู† ููŠ
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ุงู„ูŠูˆู…ุŒ ู…ุฑุชูŠู† ููŠ ุงู„ูŠูˆู…ุŒ ู…ุฑุชูŠู† ููŠ ุงู„ูŠูˆู…ุŒ ู…ุฑุชูŠู†
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Some absorption of antibacterials from aqueous by
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the anterior uvea. ุฅูŠุด uveaุŸ The anterior uvea is
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the anterior part of ciliary body. ู‡ุฐุง ุงู„ู€ anterior
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uveaุŒ ูˆููŠ ู…ู† ุงู„ู€ uvea ุงู„ู„ูŠ ู‡ูˆ ุงู„ู€ posterior part
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of ciliary body and anterior part of irisุŒ ูˆ ุงู„ู€
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posterior uvea ุงู„ู€ iris ู…ู† ูˆุงุญุฏ ู†ุตู‡ุŒ ูˆุจุฑุญุจ ู‚ูˆู„
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ุฃู†ู‡ ููŠู‡ absorption inevitable ุฑุงุญ ูŠุตูŠุฑ ู„ู„ drug by
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the uvea and lensุŒ ูƒูŠู ูŠุนู†ูŠุŸ ูŠุนู†ูŠ ุงู„ุขู† ุงู„ู€ blood
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ุจูŠุฎู„ูˆู‘ู† ููŠ ุงู„ู€ anterior chamber ูˆ ุงู„ู€ posterior
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chamberุŒ ูˆ ู…ู† ุงู„ุญุงุฌุงุช ุงู„ู„ูŠ ููŠ ุงู„ู€ anterior chamber ูˆ
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ุงู„ู€ posterior chamber ุงู„ู€ lensุŒ the lensุŒ the
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nucleusุŒ ciliary bodyุŒ ูˆุงู„ุนูŠุณู ุจูŠู‚ูˆู„ ุฅู†ู‡ ุญูŠุตูŠุฑ
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ุชุณุฑุจ ู„ู„ู…ุงุก ู„ู„ุฏูˆุงุก ููŠ ู‡ุฐู‡ ุงู„ู…ุฑุงูƒุจุงุช ุงู„ู„ูŠ ุฏุงุฎู„ู‡ุงุŒ ูŠุนู†ูŠ
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ูƒู…ุง ุฃู†ู‡ ู…ูˆู‚ุน ุงู„ุชุณุฑูŠุจ ู„ู„ุฏูˆุงุก ุจุงู„ู€ turn over ุจูŠุตูŠุฑ
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ุนุจุฑ ุดู„ู…ุณ ูƒุงู†ุงู„ุŒ ูˆ Tropical ู…ุดูˆุงุฑุŒ ุฃูŠุถู‹ุง ููŠู‡ ุดูŠุก ู…ุนูŠู†
69
00:06:34,640 --> 00:06:38,740
ู…ุง ู„ู… ูŠุชุณุฑุจ ุฃูƒุซุฑ ู…ู† ุงู„ุฏูˆุงุก ุจูŠุตูŠุฑ ุนุจุฑ ุงู„ู€ cellular
70
00:06:38,740 --> 00:06:43,980
body ูˆุนุจุฑ ุงู„ู€ iris ูˆุนุจุฑ ุงู„ู€ lensุŒ ูˆ ุจุฑูˆุญ ู„ู„ุฏู…ุนุŒ ุนุดุงู† ู‡ูŠ
71
00:06:43,980 --> 00:06:50,860
ุงู„ุฏูˆุงุก ู…ุง ูŠุจู‚ุงุด ุนู„ู‰ peakุŒ ู„ุฃู†ู‡ ููŠู‡ ุชุณุฑูŠุจุŒ ููŠู‡ leakุŒ ููŠู‡
72
00:06:50,860 --> 00:06:56,020
leakุŒ ุทูŠุจ concentrations achieved in the vitreous
73
00:06:56,020 --> 00:06:59,420
body following topical administration are
74
00:06:59,420 --> 00:07:05,640
generally subtherapeuticุŒ ู‡ุฐุง ุงู„ setting ุงู„ู€
75
00:07:05,640 --> 00:07:08,200
administration of antibacterial by local
76
00:07:08,200 --> 00:07:09,540
intravitreal injection
77
00:07:23,740 --> 00:07:28,960
ู‚ุฑู†ูŠุฉ ูˆู‡ู†ุง ุขูŠู„ูŠู†ุฒ
78
00:07:28,960 --> 00:07:40,220
ุขูŠู„ูŠู†ุฒ ุณูŠู„ุงุฑูŠ ุจูˆุฏูŠ ุฒูˆุฑูŠูˆู„ ูˆู‡ู†ุง ุงู„ ุจุชู„ุณ ูƒู„ ุงู„ู€
79
00:07:40,220 --> 00:07:44,980
chamberุŒ ู‡ุฐู‡ ุจุชู„ุณุŒ ุงู„ุขู† ุฃู†ุง ุฃุนุทูŠู‡ topical and
80
00:07:44,980 --> 00:07:45,440
antibiotic
81
00:07:56,160 --> 00:08:00,620
ููŠ ุงู„ู€ anterior chamberุŒ ูˆุจุนุฏูŠู† ููŠ ุงู„ู€ posterior chamberุŒ ูˆุจุนุฏูŠู†
82
00:08:00,620 --> 00:08:07,560
ู‡ู†ุง stopุŒ ุฅูŠุด stop ูŠุนู†ูŠุŸ ูŠุจูŠู† ู…ุด ู‡ูˆ ุงู„ู€ barrier ุงู„ู€
83
00:08:07,560 --> 00:08:12,060
lensุŒ ends on youุŒ ุงู„ู€ lens ends on youุŒ barrier ูŠุจู‚ู‰
84
00:08:12,060 --> 00:08:15,860
ุฃู†ุง ูƒูŠู ูŠุฏุฎู„ ุงู„ุฏูˆุงุก ุงู„ู„ูŠ ุฃู†ุง ูˆุถุนุชู‡ ู‡ู†ุง ููŠ ุงู„ุนูŠู†
85
00:08:15,860 --> 00:08:21,820
ูŠุฏุฎู„ ู‡ู†ุง ูˆ
86
00:08:21,820 --> 00:08:27,380
ู„ุง ูŠู…ูƒู† ู‡ูŠูƒุŒ ุงู„ุนู„ู… ุจูŠู‚ูˆู„ ู„ุง ูŠู…ูƒู† ู„ูˆ ุฃุนุทูŠูƒ ูƒู„ ุฏู‚ูŠู‚ุฉ
87
00:08:27,380 --> 00:08:33,620
ุฃู†ู‡ ูŠุณุชุทูŠุน ุฃู†ู‡ ูŠูˆุตู„ ู‡ู†ุง therapeutic level ูŠุนู†ูŠ
88
00:08:33,620 --> 00:08:46,480
ู…ู…ูƒู† ูŠุตู„ 2% 3% ู…ู† ุงู„ุฏูˆุงุก ุงู„ู„ูŠ ุฏุฎู„ุŒ ูŠุจู‚ู‰ ู‡ู†ุง ููŠู‡
89
00:08:46,480 --> 00:08:52,100
necessity ุถุฑูˆุฑุฉ ู„ูˆ ุฃู†ุง ุนู†ุฏูŠ ู‡ู†ุง infection ุฎุงุตุฉ ููŠ
90
00:08:52,100 --> 00:08:53,240
ุงู„ู€ endophthalmitis
91
00:08:55,440 --> 00:08:59,320
Endophthalmitis ุฎุทูŠุฑุฉ ูˆู„ุง ู…ุด ุฎุทูŠุฑุฉ ู‡ุฐู‡ุŸ ู‡ุฐู‡ ุฎุทูŠุฑุฉ
92
00:08:59,320 --> 00:09:06,640
ู…ุนู†ุงู‡ุง ุฃู†ู‡ ู„ูˆ ุฃู†ุง ุตุจุฑุช ูŠูˆู…ูŠู†ุŒ ูƒู„ ุงู„ุนูŠู† ู‡ุชุตูŠุฑ bag of
93
00:09:06,640 --> 00:09:12,400
pusุŒ ูƒู„ ุงู„ุนูŠู† ู‡ุชุตูŠุฑ ุฅูŠุดุŸ bag of pus ูˆ ู‡ุชุนู…ู„
94
00:09:12,400 --> 00:09:14,900
blindness ูˆ ู„ุง ูŠุดุชุบู„ .. ุญูŠุงุชู‡ ู…ุฌู†ูˆู†ุŒ blindness
95
00:09:14,900 --> 00:09:21,140
ุงู„ุนูŠู† ูƒู„ู‡ุง ุนุงูŠุฒุฉ in equation ุฃูˆ in isolation ุงู„ุนูŠู†
96
00:09:21,140 --> 00:09:25,290
ุนุงูŠุฒุฉ ุบุฑูุŒ ูŠุนู†ูŠ ุงู„ู†ุงุณ ุงู„ู„ูŠ ุจูŠูู‡ู…ูˆุง ุนู„ู‰ ุทูˆู„ ู…ู† ุฃูˆู„
97
00:09:25,290 --> 00:09:29,350
ู…ุง ุชูุฏูŠ ุนู„ุงู…ุงุช ุงู„ู€ endophthalmitis ูŠุนู†ูŠ blurring of
98
00:09:29,350 --> 00:09:36,130
visionุŒ pain ูˆ hazy cornea ูˆ ู‚ุฏุฑุด ุฃู†ุง ุฃุดูˆู ุงู„ู€ ..
99
00:09:36,130 --> 00:09:39,310
ุงู„ู„ูŠ ู‡ูˆ ุงู„ู€ retina ุนู„ู‰ ุทูˆู„ ุจู‚ูˆู„ ู‡ุฐู‡ ุจุฏุงูŠุฉ
100
00:09:39,310 --> 00:09:43,250
endophthalmitisุŒ ุชุณุฑูŠุน ุฅูŠุด ู†ุนู…ู„ุŸ ุนู„ู‰ ุทูˆู„ ุจูŠุฌูŠุจูˆู‡
101
00:09:43,250 --> 00:09:50,810
syringeุŒ syringeุŒ ุงู‡ุŒ ุจูŠุฌูŠุจูˆู‡ syringe ููŠู‡ุง
102
00:09:56,600 --> 00:10:02,880
ูˆ ุจูŠุฑูˆุญูˆุง ู‡ู†ุง ููŠ ุดูŠุก ุงุณู…ู‡ ู‡ู†ุง pars planaุŒ ููŠ ุญุฏ ูŠุณู…ู‰
103
00:10:02,880 --> 00:10:06,480
pars planaุŒ ุงู„ุฌุฒุก ุงู„ุฃู…ุงู…ูŠ ู…ู† ุงู„ู€ Cerebellum ูุดู„ู‘ุช
104
00:10:06,480 --> 00:10:09,160
ูŠุนู†ูŠ ุฃู†ุง ุฏูŠุชู†ุง ู…ุง ุชุตู„ุด ู‡ู†ุงุŒ ูŠุนู†ูŠ ุฏูŠุชู†ุง ู…ุซู„ู‹ุง ุชุจุฏุฃ ู‡ู†ุง
105
00:10:09,160 --> 00:10:15,260
ุฏูŠุชู†ุง ู…ุซู„ู‹ุง ุชุจุฏุฃ ู‡ู†ุงุŒ ุงู„ู…ู†ุทู‚ุฉ ู‡ุฐู‡ ุงุณู…ู‡ุง pars plana
106
00:10:15,260 --> 00:10:21,700
ู…ู† ุงู„ pars plana injectionุŒ Perfective Antibiotics
107
00:10:21,700 --> 00:10:27,410
ู…ุฑุฉ ูˆ 12 ุณุงุนุฉุŒ ู…ุฑุฉ ูˆ 12 ุณุงุนุฉุŒ ู…ุฑุฉ ู„ูˆ ุจุฏู†ุง .. ุฅุญู†ุง
108
00:10:27,410 --> 00:10:33,670
ู†ู‚ุฐ ุงู„ุนูŠู† ู…ู† ุงู„ู€ pusุŒ ู…ู† ุงู„ุนูŠู† ุฃู…ุง ุฃู†ู‘ู†ุง ู‡ู†ุนุทูŠู‡
109
00:10:33,670 --> 00:10:39,850
topical ุฃูˆ ุญุชู‰ ู‡ู†ุนุทูŠู‡ systemic intravenous ูŠุนู†ูŠุŒ
110
00:10:39,850 --> 00:10:43,750
intravenousุŒ ู„ุฃู† ููŠ barrier ุขุฎุฑ ุงุณู…ู‡ ุฅูŠุด ุงู„ู€ barrier
111
00:10:43,750 --> 00:10:48,630
ุงู„ุขุฎุฑุŸ retinal blood barrier
112
00:10:52,960 --> 00:10:56,400
ูุญุชู‰ ู„ูˆ ุฃู†ุง ุฃุนุทูŠุช my way ู…ุด ู‡ูƒูˆู† effective ุฒูŠ
113
00:10:56,400 --> 00:11:01,540
intravitreal injection of effective antibiotics
114
00:11:01,540 --> 00:11:07,020
ุนุงูŠุฒุฉ ุงู„ู†ู‚ุทุฉ ุชูƒูˆู† clear ุนู†ูƒู…ุŸ ุฃู†ุง ู…ุด ุนุงูŠุฒ ุฃู†ุชู…
115
00:11:07,020 --> 00:11:10,680
ุชู†ุงูุณูˆุง intravitreal injection ุจุณ ู„ูˆ ููŠ ุฎูŠุงู„ูƒูˆุง
116
00:11:10,680 --> 00:11:14,620
ุฃู†ู‡ ููŠ ุญุงู„ุฉ ุฎุงุตุฉ post operative ุนู…ู„ ุนู…ู„ูŠุฉ ุฎุงุตุฉ
117
00:11:14,620 --> 00:11:19,140
cataractุŒ ุฃูƒุซุฑ ู…ู† ุนู…ู„ูŠุงุช cataract ุฃุญูŠุงู†ู‹ุง ุจูŠุตูŠุฑ ููŠู‡ุง
118
00:11:19,140 --> 00:11:25,320
ุจุฏุงูŠุฉ infectionุŒ ู…ุฑูŠุถ ุจุฏุฃ ูŠุดู‡ุฑ ุจุงู„ู€ .. ุจุงู„ู‚ู„ู… ูˆุจู„ุงูŠูƒ
119
00:11:25,320 --> 00:11:33,520
of vegan ูˆู‡ูŠุฒูŠูƒูˆู…ูŠุง ุนู„ู‰ ุงู„ุณุฑูŠุน ู„ูˆ ููŠ team of
120
00:11:33,520 --> 00:11:38,260
ophthalmologists and surgeries to do intravitreal
121
00:11:38,260 --> 00:11:44,400
injectionุŒ ุทูŠุจ
122
00:11:44,400 --> 00:11:50,120
ุงู„ุขู† ู‡ู†ุณู‰ ุงู„ู€ .. periocular injection
123
00:11:53,410 --> 00:11:59,730
ุงู„ู€ injection ูƒู…ุง ุชุฑูˆู† ุฃู†ู‡ ู„ูŠุณ ููŠ ุงู„ู€ intravitreal ููŠ ุฃู…ุงู…
124
00:11:59,730 --> 00:12:06,510
ุงู„ุนูŠู†ุŒ ูŠุนู†ูŠ ุบุงู„ุจู‹ุง ุณุงุจ ูƒูˆู†ุฌู†ูƒุชูŠูุงู„ ุชุญุช ุงู„ู…ู„ุชุญู…ุฉ ูŠุนู†ูŠ
125
00:12:06,510 --> 00:12:10,070
ุนุงู…ุฉ ุงู„ู‡ูŠุฏุฑูˆููŠู„ูŠูƒุงุชุฑุงูƒุณ ู…ููŠุฏุฉ ุฃูƒุซุฑ ุนู†ุฏู…ุง ูŠุชู…
126
00:12:10,070 --> 00:12:17,350
ุฅุนุทุงุฆู‡ุง ุณุงุจ ูƒูˆู†ุฌู†ูƒุชูŠูุงู„ ุฑูˆุชุŒ ูŠุนู†ูŠ ุงู„ู€ epithelium ูˆ
127
00:12:17,350 --> 00:12:19,810
ุงู„ู€ endotheliumุŒ ุงู„ู€ absorption
128
00:12:23,650 --> 00:12:30,750
ูุฃู†ุง ูƒูŠู ุฃุชุบู„ุจุŸ ุฃุนู…ู„ injection subconjunctivalุŒ ู‡ุงูŠ
129
00:12:30,750 --> 00:12:35,770
ุงู„ู…ู„ุชุญู…ุฉ ุงู„ู„ูŠ ููŠู‡ุง ุงู„ู€ blood vessels ุชุญุชู‡ุงุŒ ุฃุนุทูŠ
130
00:12:35,770 --> 00:12:40,270
ู…ุซู„ู‹ุง ุฏูŠ ุทู…ูŠุณูŠู†ุŒ absorption occurs from the residual
131
00:12:40,270 --> 00:12:43,270
water ุฃูˆ ุงู„ู€ drugs of the subconjunctiva ุงู„ุฏูŠ ุจุท
132
00:12:43,270 --> 00:12:46,810
which is not subject to precordial factors as in
133
00:12:46,810 --> 00:12:52,480
topical applicationุŒ ุทุจุนู‹ุง ุฃู†ุง ู„ู…ุง ุจุฏูŠ ุฃุนุทูŠ ุตุญูŠุญ ูƒู†ุง
134
00:12:52,480 --> 00:12:59,140
ู†ูƒุชุจ ุงู„ู€ injection ู‡ู†ุง ู‡ุงูŠ ุงู„ู…ู„ุชุญู…ุฉ ู‡ู†ุง ููŠ ุงู„ู…ุทุจุฎ
135
00:12:59,140 --> 00:13:05,140
ู‡ุฐู‡ ุจุชุนุทูŠ
136
00:13:05,140 --> 00:13:09,540
ุฌุฒุก ุงู„ุฃู…ุงู… ู…ู† ุงู„ู€ sclera ุจุฏูŠ ุฃู†ุง ุฃุถุน ู‡ู†ุง
137
00:13:09,540 --> 00:13:14,900
antibiotic ู…ุนูŠู† ุงู„ู„ูŠ ู‡ูˆ ุฎุงุตุฉ ุงู„ู€ hydrophilic ุทุจุนู‹ุง
138
00:13:14,900 --> 00:13:19,580
ู„ู…ุง ุฃุนุทูŠ ุงู„ู€ hydrophilic ู‡ุชุตูŠุฑ swing ู„ู„ drugsุŒ ู‡ุชูุตู„
139
00:13:21,500 --> 00:13:27,780
ุงู„ู€ water ุงู„ู„ูŠ ุฃู†ุง ุญุงุฌุชู‡ุŒ ุงู„ู€ water ุงู„ู„ูŠ ุฃู†ุง ุญุงุฌุชู‡ุŒ ุงู„ู€ water
140
00:13:27,780 --> 00:13:36,700
ุงู„ู„ูŠ ุฃู†ุง ุญุงุฌุชู‡ุŒ ุงู„ู€ water ุงู„ู„ูŠ ุฃู†ุง ุญุงุฌุชู‡ุŒ ุงู„ู€ water
141
00:13:36,700 --> 00:13:37,560
ุงู„ู„ูŠ ุฃู†ุง ุญุงุฌุชู‡ุŒ ุงู„ู€ water ุงู„ู„ูŠ ุฃู†ุง ุญุงุฌุชู‡ุŒ ุงู„ู€ water ุงู„ู„ูŠ ุฃู†ุง
142
00:13:37,560 --> 00:13:37,600
ุงู„ู€ water ุงู„ู„ูŠ ุฃู†ุง ุญุงุฌุชู‡ุŒ ุงู„ู€ water ุงู„ู„ูŠ ุฃู†ุง ุญุงุฌุชู‡ุŒ ุงู„ู€ water
143
00:13:37,600 --> 00:13:48,720
ุงู„ู„ูŠ ุฃู†ุง ุญุงุฌุชู‡ุŒ ุงู„ู€ water ุงู„ู„ูŠ ุฃู†ุง ุญุงุฌุชู‡ุŒ ุงู„ู€ water
144
00:13:49,980 --> 00:13:54,360
ู‡ูŠ ุชุชุณู„ู„ ุงู„ุจุทุงุฑูŠุฉ ุฃูˆ ุฃุฎุฑู‰ ู…ู† ู‡ู†ุง ูˆ ู…ู† ู‡ู†ุง ุฅู„ู‰ ุฏุงุฎู„
145
00:13:54,360 --> 00:13:58,360
ุงู„ู€ aqueous ุงู„ู„ูŠ ู‡ูˆู†ุŒ ูุงู„ุขู† ุชุจู‚ู‰ symbol of restriction
146
00:13:58,360 --> 00:14:05,240
ุทูŠุจ ู…ูŠู† ุฃุณุฑุนุŒ ุฅู† ุฃู†ุง ุฃุนุทูŠุช ุงู„ุฏูˆุงุก ุงู„ู…ุงุฆูŠ ู…ู† ู‡ู†ุง ูˆู„ุง
147
00:14:05,240 --> 00:14:11,780
ู…ู† ู‡ู†ุงุŸ ู„ุฃุŒ ุจุงู„ุญูˆุงุฌุฉ ุฃุณุฑุนุŒ ุจุงู„ุญูˆุงุฌุฉ ุฃุณุฑุนุŒ ูˆ ุฃู†ุง ุฃูƒูˆู†
148
00:14:11,780 --> 00:14:17,240
ุฃุญูŠุงู†ู‹ุง ู…ุถุทุฑ ุงุถุทุฑุงุฑู‹ุง ููŠ ุญูŠุงุฉ ุงู„ูƒูˆุฑุฉ ุงู„ุฃู„ุฒุฑ ุฃู† ุฃุนุทูŠ
149
00:14:18,010 --> 00:14:24,030
Topical lipophilic antibiotic drops and
150
00:14:24,030 --> 00:14:29,590
subconjunctival hydrophilic injectionุŒ ู‡ู†ุง
151
00:14:29,590 --> 00:14:33,730
hydrophilic ูˆู‡ู†ุง lipophilicุŒ to save the cornea
152
00:14:33,730 --> 00:14:34,870
from damage
153
00:14:57,630 --> 00:15:00,010
ุงู„ูƒูˆู†ุฌูƒุชูŠูุงู„ ุฅุจูŠุซูŠู„ูŠุงู… ู‡ูˆ ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู†
154
00:15:00,010 --> 00:15:01,030
ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ
155
00:15:01,030 --> 00:15:01,690
ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู†
156
00:15:01,690 --> 00:15:05,390
ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ
157
00:15:05,390 --> 00:15:11,610
ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู†
158
00:15:11,610 --> 00:15:12,230
ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ
159
00:15:12,230 --> 00:15:18,650
ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู† ุนุจุงุฑุฉ ุนู†
160
00:15:18,650 --> 00:15:26,550
ุนู†
161
00:15:28,860 --> 00:15:32,740
Advantages of peri-ocular injectionsุŒ ู…ุง ู‡ูŠ
162
00:15:32,740 --> 00:15:39,560
ุงู„ู…ุฒุงูŠุง ู„ู„ุญุงู‚ู† ุชุญุช ุงู„ู…ู„ุชุญู…ุฉุŸ One, a clinical
163
00:15:39,560 --> 00:15:42,900
approach of administration often provides therapy
164
00:15:42,900 --> 00:15:46,420
to claim effective drug levels in aqueous for
165
00:15:46,420 --> 00:15:50,420
eight to twelve hours after a single injection
166
00:15:50,420 --> 00:15:56,760
ูŠุนู†ูŠ ุงู„ุญูู‚ู† ุฏู‡ ุฑุงุญ ู‡ุชูุถู„ ู…ู† ุซู…ุงู†ูŠุฉ ุฅู„ู‰ ุงุซู†ุง ุนุดุฑ ุณุงุนุฉ
167
00:16:04,670 --> 00:16:13,730
ุนูƒุณ ุงู„ู€ drops ูŠู…ูƒู† ุจุฏูŠ ุณุงุนุฉ ูƒู„ ุณุงุนุฉ ู…ุซู„ู‹ุงุŒ ุทูŠุจ
168
00:16:13,730 --> 00:16:18,110
flow in studies of subconjunctival injections of
169
00:16:18,110 --> 00:16:23,610
third generation cephalosporin ู…ุถุงุฏ ุญูŠูˆูŠ ุฒูŠ keflex
170
00:16:23,610 --> 00:16:28,690
injection the common levels achieved were four
171
00:16:28,690 --> 00:16:32,110
fold higher than level in aqueous concentration
172
00:16:33,730 --> 00:16:37,990
ูˆู„ู…ุง ุฃู†ุง ุนู…ู„ุช ุงู„ุญู‚ู†ุฉ ุชุญุช ุงู„ู…ู„ุชุญู…ุฉ ูˆ ู‚ุตุฏุช ุจุนุฏ ูุชุฑุฉ
173
00:16:37,990 --> 00:16:45,230
ู„ุฌูŠุช ุงู„ุชุฑูƒูŠุฒ ุฏุงุฎู„ stroma ู…ุซู„ู‹ุง ุฃูƒุซุฑ
174
00:16:45,230 --> 00:16:49,590
ู…ู† ุงู„ู€ aqueousุŒ ุชุฑูƒูŠุฒ ุงู„ุฏูˆุงุกุŒ ุฃุฑุจุนุฉ ู…ุฑุงุชุŒ ุชู„ุช ู…ุฑุงุช
175
00:16:49,590 --> 00:16:56,830
ูŠุนู†ูŠ ูŠุนู†ูŠ four ููŠ ุงู„ู€ cornea to one ููŠ ุงู„ู€ aqueousุŒ ุทูŠุจ
176
00:16:56,830 --> 00:17:02,710
ุจุฑุถู‡ ุจุนุถ ุงู„ู€ injection ููŠ ุงู„ู…ู„ุชุญู…ุฉ ุฃูŠุถู‹ุง ุชุญุช ุงู„ู…ู„ุชุญู…ุฉ
177
00:17:03,870 --> 00:17:08,370
ูˆ ูˆุฌุฏูˆุง ุฃู†ู‘ ุชุฑูƒูŠุฒ ุงู„ุฏูˆุงุก ุงู„ู…ุถุงุฏ ู„ู„ุญูŠุงุฉ ูˆุงู„ู…ุงุก ููŠ
178
00:17:08,370 --> 00:17:16,010
ุงู„ู€ choroid ุฃูƒุซุฑ ู…ู† ุงู„ู€ retina ููŠ five-fourth of the
179
00:17:16,010 --> 00:17:22,110
choroid ูˆ five-fourth ุฎู…ุณ ู…ุฑุงุช to fifteen-fourth
180
00:17:22,110 --> 00:17:29,230
ุฎู…ุณุฉ ุฅู„ู‰ ุฎู…ุณุฉ ุนุดุฑ ูŠุนู†ูŠ than of the retina ูŠุนู†ูŠ ุซู„ุงุซ
18
216
00:21:40,670 --> 00:21:45,230
ุงู„ุชู‡ุงุจ ุงู„ู‚ุฑู†ูŠุฉ ูˆู…ู†ู‡ุง ุงู„ูƒูˆุฑู†ุฆุงู„ุซุฑ ู…ูŠู† ุฃุญุณู†ุŸ ุฃุนุทูŠู‡ ุฅุจุฑุฉ
217
00:21:45,230 --> 00:21:49,270
ุตุจุงุญ ูˆู…ุณุงุก ู„ู„ูƒูˆุฑู†ุฆุงู„ุซุฑ
218
00:21:49,270 --> 00:21:57,680
ูˆู„ุง ุฃุนุทูŠู‡ ูƒู„ ุณุงุนุฉ ู‚ุทุฑุฉ ุงุชุจุนุชู†ูŠุŸ ู„ุง ุทูŠุจ ุงู„ุนูƒุณ ุฃู†ุง ููŠ
219
00:21:57,680 --> 00:22:03,760
ุนู†ุฏูŠ ู‡ู†ุง ุญุงุฌุฉ ุงุณู…ู‡ุง acute radicyclitis ุชุนุฑููˆู†
220
00:22:03,760 --> 00:22:09,600
radicyclitisุŸ ุทุจ ุนู„ุงุฌ ุงู„ูƒูˆุฑุชูŠุฒูˆู†ุŸ StimulixุŸ ูˆ
221
00:22:09,600 --> 00:22:17,160
ุงู„ูƒู„ุงู… ู‡ุฐุงุŸ ูƒูˆูŠุณุŸ BradfordุŸ ู…ูŠู† ุฃูุถู„ ู‡ู†ุงุŸ ุฃุนุทูŠ
222
00:22:17,160 --> 00:22:23,340
frequent ... frequent ุงู„ู„ูŠ ู‡ูˆ topical
223
00:22:49,540 --> 00:22:54,760
ุงู„ุญุงู„ุงุช ุงู„ู„ูŠ ุฃู†ุง ุจุจุฏุฃ ุฃุฎุชุงุฑู‡ุง ุฃุญู‚ู†ู‡ุง ููŠ ุงู„ุนูŠู† ุชุญุช
224
00:22:54,760 --> 00:22:55,360
ุงู„ู…ุฑุชุงุญุฉ
225
00:22:59,240 --> 00:23:05,980
ุฃูˆ ุงู„ุทุฑูŠู‚ุฉ ุงู„ุงู†ุชู‚ุงุฆูŠุฉ ู„ู„ุฏุฑุงุณุฉ ุชุนุชู…ุฏ ุนู„ู‰ ุฃูˆู„ู‹ุงุŒ
226
00:23:05,980 --> 00:23:10,800
ู‚ุฏุฑุฉ ุงู„ุฏูˆุงุก ุนู„ู‰ ุงู„ุชุฏุฎู„ ููŠ ุงู„ู‚ุฑู†ูŠุฉุŒ ู„ูˆ ูƒุงู†ุช
227
00:23:10,800 --> 00:23:14,880
ุงู„ุฏูˆุงุก ุฅูŠุจูˆููŠู„ูŠูƒูŠุฉ ุฃูุถู„ ุฃุนุทูŠู‡ ู‚ุทุฑุฉุŒ ู„ูˆ ูƒุงู†ุช
228
00:23:14,880 --> 00:23:18,600
ู‡ูŠุฏุฑูˆููŠู„ูŠูƒูŠุฉ ุฃุนุทูŠู‡ ุฏุจูˆุณุชูŠู† ุงุซู†ุงู†ุŒ ู…ูˆู‚ุน ู…ูˆู‚ุน
229
00:23:18,600 --> 00:23:26,690
ุงู„ู…ูˆุงุฌู‡ุฉุŒ ูˆูŠู† ุงู„ู…ุฑุถุŒ ู‡ู„ ุงู„ู…ุฑุถ ุณุทุญูŠ ูˆู„ุง ุนู…ูŠู‚ุŸ ุจู‚ูˆู„
230
00:23:26,690 --> 00:23:30,970
ุฅูŠู‡ุŸ ุงู„ general leads and lead marginsุŒ ุงู„ lead
231
00:23:30,970 --> 00:23:32,990
infection ูˆ ุงู„ lead marginsุŒ ุนุงุฑููŠู† ุงู„ lead
232
00:23:32,990 --> 00:23:36,670
margins ู‡ู†ุงุŸ ุจูŠุตูŠุฑ ููŠู‡ุง seborrheic blepharitisุŒ
233
00:23:36,670 --> 00:23:41,570
ุงุณู…ู‡ุง blepharitis ู‡ู†ุงุŒ ุจูƒุชูŠุฑูŠุง blepharitisุŒ ุฃูุถู„
234
00:23:41,570 --> 00:23:46,850
ุฃู† ูŠุนุทูŠู‡ ุฅูŠุดุŸ ointmentุŒ ู„ุฃู† ointment ุจูŠุจู‚ู‰ ุนู„ู‰ ุงู„
235
00:23:46,850 --> 00:23:52,590
lead ูˆ lead margins ุทูŠุจุŒ ุจูŠุชุŒ ูˆุงู„ุฃุฒู…... ูƒู†ุช ุฌุฏู‘ู‹ุง
236
00:23:52,590 --> 00:24:00,050
ูƒุชุงุจุฉ ู„ูŠู†ุจุณ ุงู„ู‚ุฑู†ูŠุฉ ุงู„ interior chamber ุงู„ู„ูŠ ุฃูุถู„ ุฃู†
237
00:24:00,050 --> 00:24:07,210
ุฃุนุทูŠู‡ topical frequent installation ุฃู…ุง
238
00:24:07,210 --> 00:24:12,210
solutions ุฃูˆ ุงู„ู„ูŠ ู‡ูˆ suspensions ุงู„ู…ู‡ู… ู‚ุทุฑุฉ ู„ุฃู†
239
00:24:12,210 --> 00:24:16,930
ุงู„ู…ู†ุชุฌ ู‡ู…ุงู„ ุงู„ู‚ุฑู†ูŠุฉ ูˆุญุชู‰ ุงู„ AC ู‚ุทุฑุฉ ูƒู„ ุณุงุนุฉ ุฃูˆ ูƒู„
240
00:24:16,930 --> 00:24:17,350
ุณุงุนุชูŠู†
241
00:24:27,110 --> 00:24:32,090
ู…ุด ุดุงูŠู ุฃูˆู„ 24 ุณุงุนุฉ ููŠู‡ ู…ู† ุฏุงุฎู„ู‡ ู„ู„ุญุงุฌุฑ ู…ุด ุตุนุจุฉ ุงู„
242
00:24:32,090 --> 00:24:36,010
stuff in your stomach ู…ุด ุตุนุจ ุทูŠุจ drugs
243
00:24:36,010 --> 00:24:38,890
administered systemically systemically ูŠุนู†ูŠ
244
00:24:38,890 --> 00:24:43,590
ุจุงู„ูˆุฑูŠุฏ ู…ุซู„ู‹ุง ุฃูˆ ุจุงู„ุฃู‚ุฑุงุต penetrate the aqueous and
245
00:24:43,590 --> 00:24:50,050
vitreous humor with difficulty ู„ุฃู† ููŠ ุนู†ุฏูŠ two
246
00:24:50,050 --> 00:24:53,970
barriers blood aqueous barrier ูˆ blood retinal
247
00:24:53,970 --> 00:24:57,880
barrier ูˆ ู‡ุฐุง ูƒู„ู‡ ุงุชูƒู„ู…ู†ุง ููŠู‡ Penetration into the
248
00:24:57,880 --> 00:25:00,500
aqueous humor is restricted by blood aqueous
249
00:25:00,500 --> 00:25:03,360
barrier which exists between the endothelium
250
00:25:03,360 --> 00:25:05,200
overlying the capillaries of the iris and ciliary
251
00:25:05,200 --> 00:25:11,240
body which has a tight intracellular junctions
252
00:25:11,240 --> 00:25:17,780
ูˆ Penetration
253
00:25:17,780 --> 00:25:22,240
in the vitreous ูŠุดุจู‡ ู…ู† ุงู„ุฏูˆุงุฆู„ ุงู„ุดุจูƒูŠุฉ ู„ู„ุจุชุฑูŠุณ
254
00:25:42,420 --> 00:25:53,460
ุดุงู„ ู‡ู†ุง ุดุงู„ ุงู„ุนุฏุณุฉ ูˆุงู„ุฒู†ูˆุจ ูˆูˆุถุน ู‡ู†ุง ุฏูˆุงุก ูˆู‚ุนุฏุช ุฃู†
255
00:25:53,460 --> 00:25:57,880
ุงู„ุฏูˆุงุก ุจูŠุฎุด ู‡ู†ุง ุฑุงุญ ุฒูŠู†ุŸ
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ู„ู…ุง ุดุงู„ ุงู„ุนุฏุณุฉ ูˆุงู„ุฒู†ูˆุจ ูˆูˆุถุน ู‚ุทุฑุฉ ูˆู‚ุงุณ ุจุนุฏ ูุชุฑุฉ
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ู‚ุจู„ aspiration ูŠุนู†ูŠ ุณุญุจ
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ู‡ูˆ ุฅูŠุด ุฅุฐุง ุงู„... ุงู„ุจุฑู†ุงู…ุฌ ุงู„ุนู‚... ุฅุฐุง ุงู„ุนู‚
259
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ุงู„ุชุดุฑูŠุญูŠ ู…ู† ุฃู…ุงู… ุงู„ุฏูˆุงุก ุจุณ ุนุงุฏูŠ ูŠุนู†ูŠ ู„ู…ุง ุฃุดูŠู„ ุงู„
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lens ูˆ ุฃุดูŠู„ ุงู„ zonule ู‡ูŠุตูŠุฑ ุฅูŠุด ุฃููƒูƒ ุฃููƒูƒ
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ุงููƒูƒ ุฃููƒูƒ ุฃููƒูƒ ุฃููƒูƒ ุฃููƒูƒ ุฃููƒูƒ ุฃููƒูƒ ุฃููƒูƒ ุฃููƒูƒ ุฃููƒูƒ
262
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ุงููƒูƒ ุฃููƒูƒ ุฃููƒูƒ ุฃููƒูƒ ุฃููƒูƒ ุฃููƒูƒ ุฃููƒูƒ ุฃููƒูƒ ุฃููƒูƒ ุฃููƒูƒ
263
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ุงููƒูƒ ุฃููƒูƒ ุฃููƒูƒ ุฃููƒูƒ ุฃููƒูƒ ุฃููƒูƒ ุฃููƒูƒ ุฃููƒูƒ ุฃูnear or
264
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distant ุฃู†ุช ุจุชุดูˆู ู‚ุฑูŠุจ ูˆู„ุง ู…ุด ู‚ุฑูŠุจุŸ ู…ุงููŠุด IO ุฅูŠู‡ุŸ
265
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ู‡ูˆ shallow ุนุดุงู† ุงู„ุชุฌุฑุจุฉ shallow ู…ู‚ูˆู„ ู„ูŠ ุจุฑุถู‡ ู‡ุงูŠ
266
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ุงู„ุทุฑูŠู‚ุฉ ุชุฏุฎู„ ุงู„ู†ูˆุน ุงู„ matrius ุจุณ ู‡ุงูŠ ุงู„ุทุฑูŠู‚ุฉ
267
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ุงู„ุชุฌุฑูŠุจูŠุฉ ู…ุด ุนู…ู„ูŠุฉ ูŠุนู†ูŠ ูˆููŠ ุญุงู„ุฉ ุงู„ inflammation
268
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ููŠ
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ุงู„... ุงู„
270
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... ุงู„ blood vessels ุฃูˆ ุงู„ retina ูŠูƒูˆู† ููŠู‡ ู†ูˆุน ู…ู†
271
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ุงู„ vasculitis ููŠ ุงู„ vasculitis ุฃูˆ ุงู„ retinitis ุงู„
272
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blood vessel ุงู„ู„ูŠ ุจูŠูƒูˆู† ูƒุฏู‡ ุจูŠูƒูˆู† ุงู„ endothelium
273
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tightly
274
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lining the vessel ู„ูˆ ุตุงุฑ ุจุงุณูƒูˆู„ุงุชุณ ุจูŠุตูŠุฑ...
275
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ุจุงุณูƒูˆู„ุงุชุณ ุจูŠุตูŠุฑ... ุจุงุณูƒูˆู„ุงุชุณ ุจูŠุตูŠุฑ... ุจุงุณูƒูˆู„ุงุชุณ ุจูŠุตูŠุฑ
276
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... ุจุงุณูƒูˆู„ุงุชุณ ุจูŠุตูŠุฑ... ุจุงุณูƒูˆู„ุงุชุณ ุจูŠุตูŠุฑ... ุจุงุณูƒูˆู„ุงุชุณ
277
00:27:43,130 --> 00:27:43,470
ุจูŠุตูŠุฑ... ุจุงุณูƒูˆู„ุงุชุณ ุจูŠุตูŠุฑ... ุจุงุณูƒูˆู„ุงุชุณ ุจูŠุตูŠุฑ...
278
00:27:43,470 --> 00:27:45,890
ุจุงุณูƒูˆู„ุงุชุณ ุจูŠุตูŠุฑ... ุจุงุณูƒูˆู„ุงุชุณ ุจูŠุตูŠุฑ... ุจุงุณูƒูˆู„ุงุชุณ ุจูŠุตูŠุฑ
279
00:27:45,890 --> 00:27:47,410
... ุจุงุณูƒูˆู„ุงุชุณ ุจูŠุตูŠุฑ... ุจุงุณูƒูˆู„ุงุชุณ ุจูŠุตูŠุฑ... ุจุงุณูƒูˆู„ุงุชุณ
280
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ุจูŠุตูŠุฑ... ุจุงุณูƒูˆู„ุงุชุณ ุจูŠุตูŠุฑ... ุจุงุณูƒูˆู„ุงุชุณ ุจูŠุตูŠุฑ...
281
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ุจุงุณูƒูˆู„ุงุชุณ ุจูŠุตูŠุฑ... ุจุงุณูƒูˆู„ุงุชุณ ุจูŠุตูŠุฑ... ุจุงุณูƒูˆู„ุงุชุณ ุจูŠุตูŠุฑ
282
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... ุจุงุณูƒูˆู„ุงุชุณ ุจูŠุตูŠุฑ
283
00:28:02,310 --> 00:28:06,030
... ุจุงุณูƒูˆู„ุงุชุณ ุจูŠุตูŠุฑ...
284
00:28:12,660 --> 00:28:19,640
ุงู„ู€ chapter 10 factors affecting the choice of
285
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diagnostic drugs factors ุงู„ุนูˆุงู…ู„ ุงู„ุชูŠ ุชุคุซุฑ ุนู„ู‰
286
00:28:28,140 --> 00:28:36,120
ุงุฎุชูŠุงุฑ ุงู„ุฏูˆุงุก ุงู„ุชุดุฎูŠุตูŠ ููŠ ุงู„ุนูŠู† ููŠ ุงู„ุนูŠู† ููŠ ุฃุฏูˆูŠุฉ
287
00:28:36,120 --> 00:28:41,420
ุชุดุฎูŠุตูŠุฉุŒ ูˆู‡ู†ุดูˆู ุฌูŠุด ุงู„ุฃุฏูˆุงุช ุงู„ุชุดุฎูŠุตูŠุฉ ูˆูƒูŠู ุฃู†ุง
288
00:28:41,420 --> 00:28:47,180
ุฃุฎุชุงุฑู‡ุง ููŠ ุงู„ุนูŠู† ุฃูˆ ุฏู‡ ุฏูˆุงุก ุชุดุฎูŠุตูŠ Cyclopidics
289
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ุชุดุฎูŠุต ู„ูŠู‡ุŸ ุฎุงุตุฉ
290
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ู„ู„ู€ Latent Hyperloop
291
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Esotropia. Children Esotropia. ูŠุจู‚ู‰
292
00:29:06,480 --> 00:29:09,220
PsychopoliticsุŒ this group has suffered some
293
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attritionุŒ ุชุขูƒู„. And from an original list of
294
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seven ูƒุงู†ูˆุง ู‚ุจู„ ุนุดุฑูŠู† ุณู†ุฉุŒ seven psychopolitics.
295
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Only four now remain. ุงู„ุขู† ููŠ ุฏู„ูˆู‚ุช ุฃุฑุจุนุฉ. ุฅูŠุด ุงู„
296
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... ุงู„ psychopolitics ุงู„ู„ูŠ ุฃู†ุชู… ุนุงุฑููŠู†ู‡ุงุŸ
297
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Psychopolitics
298
00:29:43,160 --> 00:30:00,520
ู…ุฏุฑูŠุงุชูƒ ู…ุฏุฑูŠุงุชูƒ ูƒุงู†ุช ู…ุฌู…ูˆุนุฉ ุทูˆูŠู„ุฉ
299
00:30:00,520 --> 00:30:01,880
ู…ู† ู…ุฌู…ูˆุนุงุช ู…ุฏุฑูŠุงุชูƒ
300
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ูุงุถู„ ุฃู† ุฃู†ุง ุนู†ุฏูŠ ู…ุฏุฑุณูŠู†
301
00:30:21,060 --> 00:30:28,500
ูŠุนู†ูŠ ูˆูุงุถู„ ุฃู† ุฃู†ุง ุนู†ุฏูŠ ูู„ุงุฆู„ ุงูุฑูŠู† more potent
302
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genetics are used prior to surgery ุทุจุนู‹ุง ุฃู†ุง
303
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ู…ุง ุจุฃุนุชุจุฑู‡ุงุด ุฃู† ุงู„ุงุทุฑุงุจูŠู† ู‡ูˆ ู…ุฏุฑู‘ูŠุงุชูƒ ู„ูˆุญุฏู‡ ู„ุฃู†ู‡ ุฅู†
304
00:30:38,630 --> 00:30:44,770
ุญุงุทุจู†ุง ุนู…ู„ ุณูŠุจูŠุฑ ุฃูŠุงุดุชุฑุง ูุงู†ู…ุง ุงู„ู…ุฏุฑูŠุงุชูŠูƒ ุงู„ู„ูŠ ู‡ูˆ
305
00:30:44,770 --> 00:30:52,330
ุดุบุงู„ ุงู„ู„ูŠ ู‡ูˆ ุงู„ู…ุฏู‘ุงุฑุน ู…ุนุงู‡ ูˆุงู„ูู„ุงู„ูู„ูŠ ุงู„ู„ูŠ ู…ุดุชู…ุด
306
00:30:52,330 --> 00:30:56,790
ุนู„ู‰ ุงู„ุณูŠู†ุงุจูˆุฏูŠ ุฅู„ุง ุจู†ุณุจุฉ ู‚ู„ูŠู„ุฉ ุฏู‡ ู‡ูˆ ุงู„ุชุดุฎูŠุต
307
00:30:56,790 --> 00:31:01,190
ุงู„ุซุงู„ุซ myotics ุงู„ู…ุถูŠู‚ุงุช
308
00:31:05,680 --> 00:31:11,360
ุงู„ุฎุทูˆุงุช ุงู„ุฃูƒุจุฑ ุญุฏุซุช ู…ู† ู‡ุฐุง ุงู„ุงู†ุชุฎุงุจ ุจู‚ูˆู„ ุฃูƒุซุฑ ู„ุณุฉ
309
00:31:11,360 --> 00:31:17,300
ู…ู†ู‡ู… ูู‚ุฏุช ู„ูˆู† ูŠุนู†ูŠ ููŠ ุฃุนุถุงุฆู‡ุง ู‡ูŠ ู‡ุฐู‡ ู…ูŠูˆุชูŠูƒุณ ู„ุฏูŠู‡ุง
310
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ุงุณุชุนู…ุงู„
311
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ูŠูˆู…ูŠุง ูŠูƒูˆู† ุซูŠุฑุงุจูŠูˆุชูŠูƒูŠ ูˆุฏูŠุงุฌู†ูˆุณุชูŠูƒูŠ ุชุดุฎูŠุตูŠ ูˆุนู„ุงุฌูŠ
312
00:31:26,940 --> 00:31:33,780
ุทุจุนู‹ุง ุจุงู„ู†ุณุจุฉ ู„ู„ุนู„ุงุฌ ูŠูƒูˆู† ู‡ู†ุง open angle glaucoma
313
00:31:35,790 --> 00:31:44,270
ูˆุงู„ุชุดุฎูŠุต ุฅูŠู‡ุŸ ูˆุงู„ุชุดุฎูŠุต ุฅูŠู‡ุŸ ุดูˆู ุงู„ pupil size ูˆุดูˆู
314
00:31:44,270 --> 00:31:48,450
ุงู„ู„ูŠ ู‡ูˆ ุงู„ muscle ... the muscle ุงู„ู„ูŠ ู‡ูŠ ุงู„ spectro
315
00:31:48,450 --> 00:31:53,030
-pili ุงู„ู‚ูˆุฉ ุจุชุงุนูƒ ุทุจ local anesthetics
316
00:32:08,770 --> 00:32:13,850
ุฃู…ุง ู…ู† ุฃู† ุงู„ู€ Optometrist ุจุงุณุชุฎุฏุงู… ู‚ูู„ ุชูˆุฑูˆู…ูŠุชุฑ
317
00:32:13,850 --> 00:32:18,810
ุจู‚ูŠุงุณ ุจุฑุทู„ุนูŠู† ุงู„ range of local anesthetics has
318
00:32:18,810 --> 00:32:23,130
remained fairly steady ู„ูƒู† ู„ู… ูŠุฒู„ ุงุณุชุนู…ุงู„ู‡ุง ุนู†ุฏ
319
00:32:23,130 --> 00:32:26,250
Optometrist ู…ูˆุฌูˆุฏุฉ ุซุงุจุชุฉ cocaine
320
00:32:29,990 --> 00:32:33,830
ุณุงูŠุฏ ุฅูŠููƒุชุณ ูƒุซูŠุฑุฉ ุจุทู„ูˆุง ูŠุณุชุนู…ู„ูˆู‡ is now really used
321
00:32:33,830 --> 00:32:38,790
medically because better agents are available ูŠุนู†ูŠ
322
00:32:38,790 --> 00:32:42,450
ุฒูŠ ุงู„ bio carbine ู…ุซู„ู‹ุง ุงู„ bio carbine ู‡ูˆ ุงู„
323
00:32:42,450 --> 00:32:48,790
dominant ู‚ุงู„ ู‡ูˆ ุงู„... ุขุณู ุงู„ bio carbine ุงู„ู„ูŠ ู‡ูˆ
324
00:32:48,790 --> 00:32:52,730
ุงู„ myotic ู„ูƒู† ุงู„ local aesthetics ู„ูˆูƒุงู„ูŠู† ู„ูŠู‡
325
00:32:52,730 --> 00:32:58,400
ุฏูˆูƒุงูŠูŠู†ุŸ ู„ูŠู‡ ุฏูˆูƒุงูŠูŠู† is dominant ุงู„ูƒูˆูƒุงูŠูŠู† ูƒุงู† ุจูŠุนู…ู„
326
00:32:58,400 --> 00:33:04,040
ุงู„ู„ูŠ ู‡ูˆ ุดูŠุก ู…ู† ุงู„ุชุณูƒูŠู† ูˆุดูŠุกุŒ ุงู„ุขู† obsolete. ุฅูŠู‡
327
00:33:04,040 --> 00:33:09,980
ูˆุตู„ุฉ ู„ู„ุฅูู„ุงุชุณุŸ ุงู„ุขู† ุงู„ู„ูŠุฏูˆ ูƒุงูŠูŠู†. ุทุจุนู‹ุง ุนู†ุฏ ุงู„ุฃุทุจุงุก
328
00:33:09,980 --> 00:33:15,720
ุงู„ุนูŠูˆู† ู…ุงููŠุด ุทุจูŠุนูŠ ู…ุณุชุบู†ู‰ ุนู† ุงู„ู„ูŠ ู‡ูˆ ุงู„ local
329
00:33:15,720 --> 00:33:18,420
anesthetic ุฃูˆ ุงู„ topical anesthetic.
330
00:33:23,520 --> 00:33:31,180
ู„ุฃู†ู‡ ู…ู‡ู… ุฌุฏู‘ู‹ุง ููŠ ุฃูŠ... ูŠุนู†ูŠ ุงู„ treatment...
331
00:33:31,180 --> 00:33:35,880
superficial treatment ู„ูƒูˆุงุจูŠุฑุง ูƒู„ูŠุฑุทูŠุฉุŒ ู…ุซู„ู‹ุง ุฅุฒุงู„ุฉ
332
00:33:35,880 --> 00:33:43,160
ุฌุณู… ุบุฑูŠุจุŒ ู‚ูŠุงุณุŒ ุงู„ู„ูŠ ู‡ูˆ ุถุบุท ุงู„ุนูŠู†ุŒ ุฃูƒูˆุงุจูŠุฑุŒ ุฃู‡ุŒ ููŠ
333
00:33:43,160 --> 00:33:45,740
ุฃุด... ุฃูƒุซุฑ ู…ู† ุฅูŠู‡ ุงู„ู„ูŠ ู‡ูˆ ุงุณุชุนู…ุงู„ ู„ูŠู‡ุŸ ุงู„ู„ูŠ ู‡ูˆ
334
00:33:45,740 --> 00:33:51,640
local ุฃูˆ topical anesthetic ููŠ ูƒู…ุงู† drugs ุงู„ู„ูŠ
335
00:33:51,640 --> 00:33:58,100
ุจุชุณุชุฎุฏู… ููŠ ุงู„optometry ุชุดุฎูŠุตูŠุฉ stains ุงู„ุฃุตุจุงุบ ุฃูŠุถู‹ุง
336
00:33:58,100 --> 00:34:05,340
this is one area that at one time appeared to have
337
00:34:05,340 --> 00:34:10,520
growth ูŠุนู†ูŠ ู‚ุจู„ ู…ุซู„ู‹ุง ุนุดุฑูŠู† ุณู†ุฉ ูƒุงู†ุช ู…ู†ุชุนุดุฉ ููŠ
338
00:34:10,520 --> 00:34:11,580
ุฃุตุจุงุบ ุฒูŠุงุฏุฉ
339
00:34:14,930 --> 00:34:19,990
two stains are used routinely ุจุณ ุงุซู†ูŠู† and the use
340
00:34:19,990 --> 00:34:25,210
of one product cease ุฏู‡ ุฏู‡ ู‡ูˆ ุงู„ king of stains
341
00:34:25,210 --> 00:34:29,850
fluorescein ู„ูƒู†
342
00:34:29,850 --> 00:34:35,950
ุฃุดูŠู„ ุจู„ูˆุฑ ูˆุจุนุถ ุงู„ drugs ุงู„ุขู† ุฃุตุจุญุช ูŠุนู†ูŠ ู‚ู„ูŠู„ุฉ
343
00:34:35,950 --> 00:34:43,390
ุฃุตุจุญุช ู‚ู„ูŠู„ุฉ ูู‡ูŠ five groups of diagnostic
344
00:34:49,230 --> 00:34:56,250
ู…ุงุฐุง ูŠุนู†ูŠ ู…ุฒุงูŠุง ุฏุฑุงุฌุงุช ุฏูŠุงุฌู…ูˆุณุชูŠูƒูŠุฉ ุฏุฑุงุฌุงุช
345
00:34:56,250 --> 00:34:56,970
ุฏูŠุงุฌู…ูˆุณุชูŠูƒูŠุฉ ุฏุฑุงุฌุงุช ุฏูŠุงุฌู…ูˆุณุชูŠูƒูŠุฉ ุฏุฑุงุฌุงุช
346
00:34:56,970 --> 00:34:58,710
ุฏูŠุงุฌู…ูˆุณุชูŠูƒูŠุฉ ุฏุฑุงุฌุงุช ุฏูŠุงุฌู…ูˆุณุชูŠูƒูŠุฉ ุฏุฑุงุฌุงุช
347
00:34:58,710 --> 00:35:01,550
ุฏูŠุงุฌู…ูˆุณุชูŠูƒูŠุฉ ุฏุฑุงุฌุงุช ุฏูŠุงุฌู…ูˆุณุชูŠูƒูŠุฉ ุฏุฑุงุฌุงุช
348
00:35:01,550 --> 00:35:02,070
ุฏูŠุงุฌู…ูˆุณุชูŠูƒูŠุฉ ุฏุฑุงุฌุงุช ุฏูŠุงุฌู…ูˆุณุชูŠูƒูŠุฉ ุฏุฑุงุฌุงุช
349
00:35:02,070 --> 00:35:02,090
ุฏูŠุงุฌู…ูˆุณุชูŠูƒูŠุฉ ุฏุฑุงุฌุงุช ุฏูŠุงุฌู…ูˆุณุชูŠูƒูŠุฉ ุฏุฑุงุฌุงุช
350
00:35:02,090 --> 00:35:06,110
ุฏูŠุงุฌู…ูˆุณุชูŠูƒูŠุฉ ุฏุฑุงุฌุงุช ุฏูŠุงุฌ
351
00:35:10,670 --> 00:35:15,790
ูŠุนู†ูŠ ู‡ุฐู‡ ุงู„ุซู„ุงุซ ู…ุฒุงูŠุง ุบุงุจุชุŒ ููŠุนู†ูŠ ุฅูŠุด ูุงุฆุฏุฉ
352
00:35:15,790 --> 00:35:23,530
ุงู„ุฏูˆุงุกุŸ ุฃูˆู„ ู…ูŠุฒุฉ easier under pressure ุณู‡ู„ ู„ู„ู…ุฑูŠุถุŒ
353
00:35:23,530 --> 00:35:27,930
ู…ุง ูŠุนู…ู„ูŠุด irritationุŒ ู…ุง ูŠุนู…ู„ูŠุด burningุŒ ู…ุง ูŠุนู…ู„ูŠุด
354
00:35:27,930 --> 00:35:28,950
stinging
355
00:35:34,970 --> 00:35:40,510
ูŠูƒูˆู† ุณู‡ู„ ู…ุง ูŠู„ูˆุซ ุซูŠุงุจู‡ ู…ุง ูŠู„ูˆุซ ุฌู„ุฏู‡ ูŠุนู†ูŠ easier to
356
00:35:40,510 --> 00:35:43,690
another patient this certainly applies when the
357
00:35:43,690 --> 00:35:46,350
procedure involves a local anesthetic ุฎุงุตุฉ ููŠ
358
00:35:46,350 --> 00:35:49,570
ุงู„ูู†ุฌุฑ ู…ูˆุถุนูŠ ุฃูˆ for other agents if the use of
359
00:35:49,570 --> 00:35:52,270
diagnostic drug will allow the examination to be
360
00:35:52,270 --> 00:35:56,670
carried out quicker and more efficiently then this
361
00:35:56,670 --> 00:36:00,290
will be to the patients advantage ูŠุนู†ูŠ ุฃู†ุง ุจุฏูŠ
362
00:36:00,290 --> 00:36:10,900
ุณุฑูŠุน ูˆุณู‡ู„ ุฃุญุท ุงู„ drug ุฃุนู…ู„ ุงู„ู‚ูŠุงุณ ูˆุฃู…ุดูŠ ุงู„
363
00:36:10,900 --> 00:36:14,980
patient ู…ุด ุนุงูŠุฒ ูŠุทูŠุจ ุงู„ุฃุณู†ุงู† ูŠุทูŠุจ ุงู„ุฃุณู†ุงู† ูŠุนู…ู„
364
00:36:14,980 --> 00:36:20,920
ุงู„ู„ูŠ ู‡ูˆ ููŠ ุงู„ุฌุงู…ุนุฉ injection ุชู†ุชุธุฑ ู†ุตู ุณุงุนุฉ ู„ุบุงูŠุฉ
365
00:36:20,920 --> 00:36:26,280
ู…ุง ูŠุนู…ู„ูƒ ุฎุฏู„ ููŠ ู†ุตู ูˆุฌู‡ูƒ ู…ู† ุฃุนู„ู‰ ู…ู† ุฃุณูู„ ูˆุฃู†ุช
366
00:36:26,280 --> 00:36:30,300
ุทุจุนู‹ุง ุฎุงูŠู ุฎูˆู ู„ุฃู†ู‡ู… ูŠู‚ูˆู„ูƒ ุชุนุงู„ ูŠุนู†ูŠ ู…ุนู†ุงู‡ ุฅูŠุด
367
00:36:30,300 --> 00:36:35,830
ู…ุง ุจุฏู‡ ูŠุฎู„ุน ูˆูŠุนู…ู„ูˆูƒู„ุงู… ุฒูŠ ู‡ุฐุงุŒ ู„ุง ุฅุญู†ุง ุจุฏู†ุง ุงู„...
368
00:36:35,830 --> 00:36:41,290
ุงู„... ุงู„ optometrist ูŠูƒูˆู† ุฅูŠุดุŸ ูŠุนู†ูŠ ุณู‡ู„ุŒ ู…ุงููŠุด ููŠู‡
369
00:36:41,290 --> 00:36:45,750
ูŠุนู†ูŠ ุนู‚ุงุจ ูŠุนู†ูŠุŒ ูŠุจู‚ู‰ ุณู‡ู„ ู„ู„ู…ุฑูŠุถุŒ ุชุนู†ูŠ easier for
370
00:36:45,750 --> 00:36:51,210
practitioners ุงู„ู…ู…ุงุฑุณุŒ ุงู„ optometristุŒ ูุฃู†ุง ุจู‚ุฏุฑุด
371
00:36:51,210 --> 00:36:56,870
ุจู‚ู‰ ุฅุญู†ุง ุจู†ุญุท ู†ู‚ุทุฉ ุงู„... ุงู„... ุงู„... ุงู„ ุงู„ูˆูƒูŠูŠู† ู„ุฃู†ู‡
372
00:36:56,870 --> 00:37:01,130
ุนู„ู‰ ุทูˆู„ ุจูŠุชุฌุงูˆุจ ู…ุง ูŠูˆุด ุงู„ู…ุฑูŠุถ ูŠุชู‚ู„ู‚ ู…ุซู„ู‹ุง ู„ู…ุง ุญุท ู†ู‚ุทุฉ
373
00:37:01,130 --> 00:37:06,250
ุงู„ููŠุฑูˆุณูŠู† ุชุตุจุบ ุงู„ู…ูƒุงู† ุนู„ู‰ ุทูˆู„ ู…ุง ูŠูˆุด ุญุท ู„ุง ุญุท ูƒู…ุงู†
374
00:37:06,250 --> 00:37:09,990
ูˆุงุญุฏุฉ ุฃูˆ ูƒู…ุงู† ูˆุงุญุฏุฉ ุงู„ุงู†ุชุฌุงุฑ ู…ู† ู…ุฌู„ุณ ู…ุฌู„ุณ ู…ุฌู„ุณ
375
00:37:09,990 --> 00:37:11,390
ู…ุฌู„ุณ ู…ุฌู„ุณ ู…ุฌู„ุณ ู…ุฌู„ุณ ู…ุฌู„ุณ ู…ุฌู„ุณ ู…ุฌู„ุณ ู…ุฌู„ุณ ู…ุฌู„ุณ ู…ุฌู„ุณ
376
00:37:11,390 --> 00:37:11,550
ู…ุฌู„ุณ ู…ุฌู„ุณ ู…ุฌู„ุณ ู…ุฌู„ุณ ู…ุฌู„ุณ ู…ุฌู„ุณ ู…ุฌู„ุณ ู…ุฌู„ุณ ู…ุฌู„ุณ ู…ุฌู„ุณ
377
00:37:11,550 --> 00:37:24,770
ู…ุฌู„ุณ ู…ุฌู„ุณ ู…ุฌู„ุณ ู…ุฌู„ุณ ู…ุฌ
378
00:37:25,030 --> 00:37:28,950
ูู„ูˆุฑูŠุณูŠู†ุŸ ุทูŠุจ ุจุชุงุฑูŠูƒุฒุงู…ูŠู† ุฃุดูˆู ุฅู† ูˆุฅู…ุง ุงู„ results
379
00:37:28,950 --> 00:37:34,870
ูƒูˆูŠุณุฉ ู…ูŠูƒูˆู†ุด ู…ุฑุดูˆุด ูˆู„ุง ู…ุฎุงูุฑ again in the case of
380
00:37:34,870 --> 00:37:37,990
midletics and cyclopidics the results obtained
381
00:37:37,990 --> 00:37:42,490
will often be more valuable ูŠุนู†ูŠ ุฅูŠุด more valuable
382
00:37:42,490 --> 00:37:50,270
ู‚ูŠู…ุฉ ูŠุนู†ูŠ ุชูƒูˆู† accurate ู…ูŠูƒูˆู†ุด
383
00:37:50,270 --> 00:37:51,370
drug facet
384
00:37:54,710 --> 00:37:58,830
ููŠ ุงู„ุฑุทูˆุจุฉ ุงู„ุญุฑุงุฑุฉ ุงู„ู…ุบูŠุฑุฉ ุงู„ุชุฑูƒูŠุฒูŠ ุจุชุงุนู‡ู… ุงู„ู„ูŠ
385
00:37:58,830 --> 00:38:04,770
ูŠู‚ูˆู„ ููŠู‡ุŸ ูŠุจู‚ู‰ ู‡ุฐู‡ ุซู„ุงุซ ู…ุฒุงูŠุง easy to patient easy
386
00:38:04,770 --> 00:38:07,710
to practitioner or better examination
387
00:38:24,470 --> 00:38:30,030
ุฅูŠุด ู…ุณุงูˆุฆ ุฃูˆ ุงู„ุนูŠูˆุจุŸ ุจูŠู‚ูˆู„ ุฃูˆู„ู‹ุง ุฃู† ุงู„ู€ I is an
388
00:38:30,030 --> 00:38:35,130
artificial state this must be allowed for when
389
00:38:35,130 --> 00:38:39,610
carrying out certain tasks ูŠุนู†ูŠ ุฃู†ุง ุงู„ู„ูŠ ุญุทูŠุชู‡
390
00:38:39,610 --> 00:38:46,290
ู…ุฏุฑู‘ูŠุงุณูŠุณ ุงู„ุขู† ุฃู†ุง ู‡ูŠุฑู… ููŠ ุงู„ุชุดุฑูŠุญ ุงู„ู„ูŠ ุนู†ุฏูŠ ุงู„ุจู‚ุจ
391
00:38:46,290 --> 00:38:53,490
ุงู„ู„ูŠ ูƒุงู† Diameter ุจุชุงุนู‡ four ุฃูˆ five ุงู„ู€ Millimeter
392
00:38:53,490 --> 00:39:04,390
ุตุงุฑ 10 ุฃูˆ 9 ุบูŠุฑุช ู…ู† ู…ุง ุบูŠุฑุช ุงู„ุนุถู„ุฉ ุงู„ู„ูŠ ูƒุงู†ุช ุณูˆุฑุชุง
393
00:39:04,390 --> 00:39:08,870
ุจูŠูˆุจูŠู„ูŠ ุดุบุงู„ุฉ ุงู„ุขู† ุตุงุฑุช ูุชู„ุฉ ู…ุงููŠู‡ ู‚ุทุฑุฉ ูˆู‡ูŠ ู…ุด
394
00:39:08,870 --> 00:39:16,110
ุดุบุงู„ุฉ ูŠุจู‚ู‰ ุฃู†ุง ุฃู‡ุฏุงู ุชุบูŠูŠุฑ ุทุจ ุงู„ุขู† ุฃู†ุง ู„ูˆ ุญุทูŠุช
395
00:39:16,110 --> 00:39:17,450
ู…ุซู„ู‹ุง ู„ุทูู„ุฉ
396
00:39:27,220 --> 00:39:32,680
ูˆุฃู†ุง ู…ุง ุจู†ุทู„ุน ููŠ ุงู„ุดู…ุณ ุจุณ ู…ุนู†ุงู‡ ุฃู† ุฃู†ุง ู…ุง ุจุนู…ู„ุด ุจุณ
397
00:39
431
00:42:16,490 --> 00:42:20,210
drug? if it is available might exacerbate that
432
00:42:20,210 --> 00:42:20,550
problem.
433
00:42:27,850 --> 00:42:34,090
ุงู„ุฏุฑุงุฌุงุช ู…ู…ูƒู† ุฃู† ุชู†ุชู‡ูŠ ู…ู†ู‡ุงุŒ ู„ูŠุณ ุฃู† ุชู‚ุทุน ุงู„ู‚ุทุฑุฉ
434
00:42:34,090 --> 00:42:40,430
ูˆุชุนู…ู„ ุชุฃุซูŠุฑ ุฏุงุฆู…ุŒ ุทุจุนุง ู‡ูŠ ุงู„ู‚ุทุฑุฉ ู…ู…ุง ูŠุดูŠ reversible
435
00:42:40,430 --> 00:42:47,530
ุฃูˆ ุงู„ู€ local adverse effects ุนู„ู‰
436
00:42:47,530 --> 00:42:54,830
ุงู„ุนูŠู† ุจุณุŒ ุจูŠู†ู…ุง ุงู„ุชุงู†ูŠุฉ systemic ุนู„ู‰ ุงู„ุฌุณู… ุทุจ local
437
00:42:54,830 --> 00:42:59,270
adverse if it's this can be as mild as stinging
438
00:42:59,270 --> 00:43:08,250
ูŠุนู†ูŠ ุฎููŠูุฉ ุฒูŠ ุงู„ุชู„ุฎูŠุฒ ุนุงุฑููŠู† ุงู„ูˆุฑุฒ ุงู‡ ุงูˆ as severe
439
00:43:08,250 --> 00:43:12,310
as angioedema angioedema
440
00:43:32,400 --> 00:43:38,100
ู‡ุฐุง ุงู„ุฑูˆุช ุฑูˆุช ุงูŠุฑูŠุณ ููŠ ุงู„ุณูŠุงุฑุฉ ุงู„ุจูˆุฏูŠุŒ ูŠุจู‚ู‰
441
00:43:38,100 --> 00:43:40,540
ุงู„ู…ุณุงูุฉ ู…ู† ู‡ู†ุง ู„ ู‡ู†ุง ุญุงู„ุฉ ุงู„ ุงูŠุฑูŠุณ ููŠ ุงู„ุญุงู„ุฉ
442
00:43:40,540 --> 00:43:40,860
ุงู„ุนุงุฏูŠุฉ
443
00:43:57,950 --> 00:44:02,910
ูŠุนู†ูŠ ุฃู† ุงู„ู€ iris ุงู„ู„ูŠ ูƒุงู† ูˆุงุตู„ ู‡ู†ุง ูŠุชุฌู…ุน ู…ู† ุงู„ู€
444
00:44:02,910 --> 00:44:07,710
over grounding ุนู„ู‰ ุงู„ angle of ACุŒ angle of
445
00:44:07,710 --> 00:44:14,150
anterior chamberุŒ ู‡ูŠุณูƒุฑ ุงู„ุฒุงูˆูŠุฉุŒ ูู„ูˆ ุงู„ุฒุงูˆูŠุฉ ู†ุงุฑุชุŒ
446
00:44:14,150 --> 00:44:17,590
ุณูŠุจูŠุฑ
447
00:44:17,590 --> 00:44:17,950
ุงู„ closure
448
00:44:26,690 --> 00:44:35,550
ุนู„ู‰ 50 ุฅู„ู‰ 70 ู…ูŠู„ูŠ ู…ุชุฑ ุฒูŠ ุงู‚ู„ ุณูŠุจูŠุฑ
449
00:44:35,550 --> 00:44:40,190
ุฏู…ุฌ ููŠ ุงู„ุนูŠู† ุณูŠุจูŠุฑ ุฏู…ุฌ ุงูˆูƒุชูƒู†ูŠุฉ ู‡ู„ ุงู„ุฏู…ุฌ ู‡ุฐุง
450
00:44:40,190 --> 00:44:45,510
reversible ุงูˆ irreversible ู‡ุฐุง
451
00:44:45,510 --> 00:44:49,630
ุงู„ุฏู…ุฌ irreversible ูŠุจู‚ู‰ ุงุญู†ุง ู…ู„ู‚ู†ุง ู…ู† ุงู„ side
452
00:44:49,630 --> 00:44:52,350
effects ุงู„ุจุณูŠุทุฉ ุญุฑุฌุงู†
453
00:45:01,280 --> 00:45:10,900
ูˆู„ุง ุญุงุฌุฉุŒ ู„ูƒู† ุงู„ุฎุจุฑ ู‡ู†ุง ููŠ ุจุนุถ ุงู„ู‚ุทุฑุงุช ุชุนู…ู„ ุชู„ูˆู†
454
00:45:10,900 --> 00:45:15,960
ุฏุงุฆู… ููŠ ุงู„ู€IrisุŒ ุงู„ู€Iris ุญุชู‰ ุงู„ู„ูŠ ู†ุตู ูุงุชุญ ุฃูˆ ูุงุชุญ
455
00:45:15,960 --> 00:45:17,920
ุดูˆูŠุฉุŒ ู…ู…ูƒู† ูŠุตูŠุฑ black
456
00:45:26,820 --> 00:45:32,220
ุฒู„ุชุงู† .. ุฒู„ุชุงู† ู‡ุฑู‚ .. ุงู†ุช ุฌุงู‡ุฒ ู„ุฒู„ุชุงู† ู‡ุฑู…ูˆู†ูŠุฉ ุฎุทุฑ
457
00:45:32,220 --> 00:45:36,120
ู„ู„ู€ Antiglucoma .. Antiglucoma ุฏุฑุฌุฉ ููŠ ู…ู†ู‡ุง ุฎุทุฑ
458
00:45:36,120 --> 00:45:46,580
ุงุณู…ู‡ุง ุงู„ูŠูˆู…ูŠุฌุงู† ุงู„ูŠูˆู…ูŠุฌุงู† ุงู„ูŠูˆู…ูŠุฌุงู† ุงูˆ ุฒู„ุชุงู† ู…ู…ูƒู†
459
00:45:46,580 --> 00:45:51,940
ุชุณู…ู‰ ุชู„ูˆูŠู† ุฏุงุฆู… ููŠ ุงู„ุนูŠุงุฑุงุช ุชู„ูˆูŠู† ุฏุงุฆู… ููŠ ุงู„ุนูŠุงุฑุงุช
460
00:46:06,670 --> 00:46:11,270
ุงู„ู€ side effects ุจุชูƒูˆู† systemic at this ุงู„ู„ูŠ ู‡ูˆ
461
00:46:11,270 --> 00:46:15,710
systemic ููŠ ุงู„ุจู„ุฏ ูŠุนู†ูŠ many diagnostic drugs are
462
00:46:15,710 --> 00:46:20,550
potent ู‚ูˆูŠุฉ ูŠุนู†ูŠ modifiers of autonomic nervous
463
00:46:20,550 --> 00:46:24,150
system and are capable of causing effects of
464
00:46:24,150 --> 00:46:26,970
automatically innervated structures ูŠุนู†ูŠ ุนุดุงู†
465
00:46:26,970 --> 00:46:31,950
ุฃุฑูŠู‡ู… ู…ุซู„ุง ู„ูˆ ุฃู†ุง ุฃุนุทูŠุช ุฅู†ูุงู† ุฃุชุฑูˆุจูŠุง ุนู†ุฏู‡
466
00:46:31,950 --> 00:46:36,790
ุฃุฒูˆุชุฑูˆุจูŠุง ุฃุนุทูŠุชู‡ ุฃุชุฑูˆุจูŠุงุทุจุนุง ุงู„ atropine ู‡ูŠุฏุฎู„ ู…ู†
467
00:46:36,790 --> 00:46:40,750
ุงู„ุนูŠู† ู†ุงุฒู„ ูˆ ู„ุงูƒุชู… ุนู„ู‰ ุงู„ duct ูˆ ูŠู†ุฒู„ ุนู„ู‰ ุงู„ nose
468
00:46:40,750 --> 00:46:44,190
ู†ุงุฒู„ ู…ู† ู‚ุณู… ุงู„ brain rich of blood vessels ูˆ ุฑูˆุญ
469
00:46:44,190 --> 00:46:51,530
ุนู„ู‰ ุงู„ุฏู… ุจุณุฃู„ูˆู†ูŠ ุงู†ุง ููŠ ุงู„ุชุฎุฑุฌ ุงู„ุฏูƒุชูˆุฑุฉุŒ ุจู‚ูˆู„ู‡ุง
470
00:46:51,530 --> 00:46:53,790
ุงู„ุฏูƒุชูˆุฑ ูƒุงู† atropine
471
00:47:03,970 --> 00:47:11,390
ููŠ ุนูŠู†ูŠ ุฃูˆ ุจุตูˆุช ูŠุนู†ูŠ ุงุฎุทุทุง ุงุฎุฐูˆุง ุงู„ุจู„ุฏ ุจุงู„ุชู…
472
00:47:11,390 --> 00:47:16,490
ู…ู‚ุฑู…ูˆู† ุดุบู„ู†ุง
473
00:47:16,490 --> 00:47:20,450
ุงุญู†ุง ุงู„ autonomous nervous system ูˆุนู…ู„ ู„ูŠู‡
474
00:47:20,450 --> 00:47:24,750
toxicity drug toxicity ูˆู„ู…ู‘ุง ุงู„ infants ูˆุฒู†ู‡ ู‚ู„ูŠู„
475
00:47:24,750 --> 00:47:26,450
ู…ู…ูƒู† ูŠูƒูˆู† overdose ู…ู‚ุฑู…ูˆู†
476
00:47:30,040 --> 00:47:34,660
ุชุดูˆููˆุง ุงู„ุนู„ุจ ุงู„ุฏูˆุงู… ุงู„ู…ูƒุชูˆุจ ุนู„ูŠู‡ุง ูŠุญูุธ ุนูŠุฏุง ุนู† ุนูŠู†
477
00:47:34,660 --> 00:47:40,960
ุงู„ุฃูˆู„ุงุฏ ุฃูˆ ุงู„ุฃุทูุงู„ ุตุญูŠุญ ู…ู…ูƒู† ูƒูˆุฑุณ ูˆุงุญุฏ ูŠุฎุชู… ูˆู…ู…ูƒู†
478
00:47:40,960 --> 00:47:45,140
ู„ูˆ ุงู„ drug ุงุณุชุฎุฏู… ุญุชู‰ ููŠ ุงู„ุนูŠู† ุงู„ุฃุทูุงู„ ู…ู…ูƒู† ูŠุนู…ู„ู‡ู…
479
00:47:45,140 --> 00:47:51,680
systemic adverse effects ุทูŠุจ ุฃุฎุฑ ุดุฆ ุฎู„ุต ู…ู†ู‡
480
00:48:01,950 --> 00:48:12,890
ุงู„ุดูŠุก ูŠุฌุจ ุฃู† ูŠูƒูˆู† ู…ุชูˆูุฑุŒ ูŠุฌุจ
481
00:48:12,890 --> 00:48:16,950
ุฃู† ูŠูƒูˆู† ู…ุชูˆูุฑุŒ ูŠุฌุจ ุฃู† ูŠูƒูˆู† ู…ุชูˆูุฑุŒ ูŠุฌุจ ุฃู† ูŠูƒูˆู†
482
00:48:16,950 --> 00:48:24,840
ู…ุชูˆูุฑุŒ ูŠุฌุจ ุฃู† ูŠูƒูˆู† ู…ุชูˆูุฑุŒ ูŠุฌุจ ุฃู† ูŠูƒูˆู† ู…ุชูˆูุฑ 3- its
483
00:48:24,840 --> 00:48:31,800
action should be fast in answer 4
484
00:48:31,800 --> 00:48:35,960
-
485
00:48:35,960 --> 00:48:38,420
its action should be short in duration
486
00:48:50,610 --> 00:48:56,330
ุงู„ุฏุฑุงุฌุฉ ูŠุฌุจ ุฃู† ู„ุง ุชูƒูˆู† ู„ุฏูŠู‡ุง ุงููƒุงุฑ ูุงุฑู…ุงุฑูˆูƒูˆู„ูŠุฌูŠุฉ
487
00:48:56,330 --> 00:49:00,130
ุบูŠุฑ ุงุฏุฑุงุณูŠุฉุŒ
488
00:49:00,130 --> 00:49:06,030
ู„ุง ุชูƒูˆู† ู„ุฏูŠู‡ุง ุงููƒุงุฑ ูุงุฑู…ุงุฑูˆูƒูˆู„ูŠุฌูŠุฉ ุบูŠุฑ ุงุฏุฑุงุณูŠุฉุŒ ู„ุง
489
00:49:06,030 --> 00:49:09,430
ุชูƒูˆู†
490
00:49:09,430 --> 00:49:12,950
ู„ุฏูŠู‡ุง ุงููƒุงุฑ ูุงุฑู…ุงุฑูˆูƒูˆู„ูŠุฌูŠุฉ ุบูŠุฑ ุงุฏุฑุงุณูŠุฉ
491
00:49:18,000 --> 00:49:24,000
Present ูŠุนู†ูŠ ู…ูุฑุญ ูˆ easy to use till it should be
492
00:49:24,000 --> 00:49:28,560
capable of being produced in stable and sterile
493
00:49:28,560 --> 00:49:33,120
ophthalmic form that is appropriate to the use for
494
00:49:33,120 --> 00:49:37,680
which is intended ูŠุนู†ูŠ ุงู†ุง ุญุถุฑุชู‡ ู…ุซู„ุง
495
00:49:37,680 --> 00:49:41,560
psychologically ู„ู…ุฏุฉ ุณู†ุฉ ู…ุด ุฎูŠุงู„ ุณุงู‰ ูŠุชุญู„ู„ ูˆ ูŠุฎุฑุจ
496
00:49:41,560 --> 00:49:43,960
ุญุถุฑุช ุงู„
497
00:49:53,930 --> 00:49:58,970
ู…ุซู„ุง ุงุญุท ู…ุฑู‡ู… ููŠ ุงู„ุนูŠู† ูุงูƒุฏุงุด ุงูŠู‡ ุนู…ู„ ุฑูŠุชู†ูˆุณูƒูˆุจูŠ ูˆ
498
00:49:58,970 --> 00:50:04,730
ู‡ูŠูˆุตู„ ู…ุดูƒู„ุฉุŒ ู„ุฃ ู…ุฏูŠุด ุงู†ุง ุงูŠู‡ุŒ ู„ูŠู‡ ูˆูŠู‡ ูƒู„ ุงู„ุนู…ู„
499
00:50:04,730 --> 00:50:05,250
ุงู„ุชุงู„ูŠุŸ
500
00:50:10,900 --> 00:50:14,460
and the advantages and disadvantages of a proposed
501
00:50:14,460 --> 00:50:18,300
drug must be weighed in the light of a particular
502
00:50:18,300 --> 00:50:21,720
patient immediately prior to the examination ูŠุจู‚ู‰
503
00:50:21,720 --> 00:50:24,940
ู…ู† ุนูŠุงู† ู„ุนูŠุงู† ุจูŠุฎุชู„ู ููŠ ุนูŠุงู† ุจูŠู…ุดูŠ ู…ุนุงู‡ ู„ู„ู‡ู„ุงุฌุฉ
504
00:50:24,940 --> 00:50:28,400
ูˆุนูŠุงู† ู…ุงุจู…ุดูŠ ู…ุนุงู‡ ุนูŠุงู† ุจุณุฑุนุฉ ุจูŠุฑูˆุญ ู…ู†ู‡ ูˆุนูŠุงู† ุจูŠุทูˆู„
505
00:50:28,400 --> 00:50:32,280
ู…ุนุงู‡ ุนูŠุงู† ุจูŠุฃูˆู„ ุนูŠู†ู‡ ูˆุนูŠุงู† ู…ุงุจูŠุฃูˆู„ ุนูŠู†ู‡ ูˆูƒุฏู‡ ู„ูƒู†
506
00:50:32,280 --> 00:50:38,800
ุงู†ุง ููŠ ุงู„ุขุฎุฑ ุจุญูƒู… ุนู„ู‰ ุฅูŠุด ุฅู…ูƒุงู†ูŠุฉ ุงู„ุฏูˆุงุก ุงู„ู…ู†ุงุณุจ
507
00:50:38,800 --> 00:50:39,320
ู„ู„ูุญุต
508
00:50:42,660 --> 00:50:46,060
ุจุงู„ู†ุณุจุฉ ู„ู…ุง ุญุทูˆุง ูŠุง ู…ุงู„ุณุชุงู†ูŠ ุจุฏูŠ Cycloblasia ูŠุง
509
00:50:46,060 --> 00:50:50,080
ู…ุงู„ูŠ effective Cycloblasia ุจู‚ุนุฏ ู†ู‚ุฏุฑ ุนู„ู‰ ูู„ุงู† ุญุงุฌุฉ
510
00:50:50,080 --> 00:50:54,160
ูŠุนู†ูŠ ููŠ ุนู†ุฏู‡ ุญุฑูุฉ ูู„ุงู† ู…ุง ุนู†ุฏู‡ ุญุฑูุฉ ูˆูƒู„ุงู… ุฒูŠ ู‡ุฐุง
511
00:50:54,160 --> 00:50:58,640
ุงู„ู…ู‡ู… ุงู†ู‡ ุนู…ู„ effective and easy examination ุดูƒุฑุง
512
00:50:58,640 --> 00:51:00,180
ู„ูƒู… ูˆุงู„ุณู„ุงู… ุนู„ูŠูƒู… ูˆุฑุญู…ุฉ ุงู„ู„ู‡ ูˆุจุฑูƒุงุชู‡