### Human
stringlengths 17
391
| ### Assistant
stringlengths 10
790
| text
stringlengths 77
866
|
|---|---|---|
How long is the variation length for RS1555282775 SNP? | The variation length is 1 base pairs. | <s>[INST] How long is the variation length for RS1555282775 SNP? [/INST] The variation length is 1 base pairs. </s> |
What is the origin for RS1555282775 SNP? | The origin is germline. | <s>[INST] What is the origin for RS1555282775 SNP? [/INST] The origin is germline. </s> |
What is the type of genetic variation for RS1555282775 SNP? | The variation is a single nucleotide variant. | <s>[INST] What is the type of genetic variation for RS1555282775 SNP? [/INST] The variation is a single nucleotide variant. </s> |
What is the genetic molecular consequence for RS1555282775 SNP? | The resulting gene consequence is a nonsense. | <s>[INST] What is the genetic molecular consequence for RS1555282775 SNP? [/INST] The resulting gene consequence is a nonsense. </s> |
Which condition is asociated with RS1555294600 SNP? | Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1555294600 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1555294600 SNP. | <s>[INST] Which condition is asociated with RS1555294600 SNP? [/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1555294600 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1555294600 SNP. </s> |
In which chromosome is RS1555294600 SNP located? | It is located in the chromosome 13. | <s>[INST] In which chromosome is RS1555294600 SNP located? [/INST] It is located in the chromosome 13. </s> |
Which methods support the evidence found for the RS1555294600 SNP? | Associated methods are: clinical testing. | <s>[INST] Which methods support the evidence found for the RS1555294600 SNP? [/INST] Associated methods are: clinical testing. </s> |
What is the clinical significance of RS1555294600 SNP, is it benign or pathogenic? | It is Pathogenic. | <s>[INST] What is the clinical significance of RS1555294600 SNP, is it benign or pathogenic? [/INST] It is Pathogenic. </s> |
How long is the variation length for RS1555294600 SNP? | The variation length is 2 base pairs. | <s>[INST] How long is the variation length for RS1555294600 SNP? [/INST] The variation length is 2 base pairs. </s> |
What is the origin for RS1555294600 SNP? | The origin is germline. | <s>[INST] What is the origin for RS1555294600 SNP? [/INST] The origin is germline. </s> |
What is the type of genetic variation for RS1555294600 SNP? | The variation is a Insertion. | <s>[INST] What is the type of genetic variation for RS1555294600 SNP? [/INST] The variation is a Insertion. </s> |
What is the genetic molecular consequence for RS1555294600 SNP? | The resulting gene consequence is a frameshift variant. | <s>[INST] What is the genetic molecular consequence for RS1555294600 SNP? [/INST] The resulting gene consequence is a frameshift variant. </s> |
Which condition is asociated with DEL527719? | Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsDEL527719. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/DEL527719. | <s>[INST] Which condition is asociated with DEL527719? [/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsDEL527719. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/DEL527719. </s> |
In which chromosome is DEL527719 located? | It is located in the chromosome 13. | <s>[INST] In which chromosome is DEL527719 located? [/INST] It is located in the chromosome 13. </s> |
Which methods support the evidence found for the DEL527719? | Associated methods are: clinical testing. | <s>[INST] Which methods support the evidence found for the DEL527719? [/INST] Associated methods are: clinical testing. </s> |
What is the clinical significance of DEL527719, is it benign or pathogenic? | It is Pathogenic. | <s>[INST] What is the clinical significance of DEL527719, is it benign or pathogenic? [/INST] It is Pathogenic. </s> |
How long is the variation length for DEL527719? | The variation length is 176171 base pairs. | <s>[INST] How long is the variation length for DEL527719? [/INST] The variation length is 176171 base pairs. </s> |
What is the origin for DEL527719? | The origin is germline. | <s>[INST] What is the origin for DEL527719? [/INST] The origin is germline. </s> |
What is the type of genetic variation for DEL527719? | The variation is a Deletion. | <s>[INST] What is the type of genetic variation for DEL527719? [/INST] The variation is a Deletion. </s> |
Which condition is asociated with RS1566234123 SNP? | Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1566234123 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1566234123 SNP. | <s>[INST] Which condition is asociated with RS1566234123 SNP? [/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1566234123 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1566234123 SNP. </s> |
In which chromosome is RS1566234123 SNP located? | It is located in the chromosome 13. | <s>[INST] In which chromosome is RS1566234123 SNP located? [/INST] It is located in the chromosome 13. </s> |
Which methods support the evidence found for the RS1566234123 SNP? | Associated methods are: clinical testing. | <s>[INST] Which methods support the evidence found for the RS1566234123 SNP? [/INST] Associated methods are: clinical testing. </s> |
What is the clinical significance of RS1566234123 SNP, is it benign or pathogenic? | It is Pathogenic. | <s>[INST] What is the clinical significance of RS1566234123 SNP, is it benign or pathogenic? [/INST] It is Pathogenic. </s> |
How long is the variation length for RS1566234123 SNP? | The variation length is 1 base pairs. | <s>[INST] How long is the variation length for RS1566234123 SNP? [/INST] The variation length is 1 base pairs. </s> |
What is the origin for RS1566234123 SNP? | The origin is germline. | <s>[INST] What is the origin for RS1566234123 SNP? [/INST] The origin is germline. </s> |
What is the type of genetic variation for RS1566234123 SNP? | The variation is a Duplication. | <s>[INST] What is the type of genetic variation for RS1566234123 SNP? [/INST] The variation is a Duplication. </s> |
What is the genetic molecular consequence for RS1566234123 SNP? | The resulting gene consequence is a frameshift variant. | <s>[INST] What is the genetic molecular consequence for RS1566234123 SNP? [/INST] The resulting gene consequence is a frameshift variant. </s> |
Which condition is asociated with RS1566199059 SNP? | Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1566199059 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1566199059 SNP. | <s>[INST] Which condition is asociated with RS1566199059 SNP? [/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1566199059 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1566199059 SNP. </s> |
In which chromosome is RS1566199059 SNP located? | It is located in the chromosome 13. | <s>[INST] In which chromosome is RS1566199059 SNP located? [/INST] It is located in the chromosome 13. </s> |
Which methods support the evidence found for the RS1566199059 SNP? | Associated methods are: clinical testing. | <s>[INST] Which methods support the evidence found for the RS1566199059 SNP? [/INST] Associated methods are: clinical testing. </s> |
What is the clinical significance of RS1566199059 SNP, is it benign or pathogenic? | It is Pathogenic. | <s>[INST] What is the clinical significance of RS1566199059 SNP, is it benign or pathogenic? [/INST] It is Pathogenic. </s> |
How long is the variation length for RS1566199059 SNP? | The variation length is 2 base pairs. | <s>[INST] How long is the variation length for RS1566199059 SNP? [/INST] The variation length is 2 base pairs. </s> |
What is the origin for RS1566199059 SNP? | The origin is germline. | <s>[INST] What is the origin for RS1566199059 SNP? [/INST] The origin is germline. </s> |
What is the type of genetic variation for RS1566199059 SNP? | The variation is a Deletion. | <s>[INST] What is the type of genetic variation for RS1566199059 SNP? [/INST] The variation is a Deletion. </s> |
What is the genetic molecular consequence for RS1566199059 SNP? | The resulting gene consequence is a frameshift variant. | <s>[INST] What is the genetic molecular consequence for RS1566199059 SNP? [/INST] The resulting gene consequence is a frameshift variant. </s> |
Which condition is asociated with RS1566186087 SNP? | Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1566186087 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1566186087 SNP. | <s>[INST] Which condition is asociated with RS1566186087 SNP? [/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1566186087 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1566186087 SNP. </s> |
In which chromosome is RS1566186087 SNP located? | It is located in the chromosome 13. | <s>[INST] In which chromosome is RS1566186087 SNP located? [/INST] It is located in the chromosome 13. </s> |
Which methods support the evidence found for the RS1566186087 SNP? | Associated methods are: clinical testing. | <s>[INST] Which methods support the evidence found for the RS1566186087 SNP? [/INST] Associated methods are: clinical testing. </s> |
What is the clinical significance of RS1566186087 SNP, is it benign or pathogenic? | It is Pathogenic. | <s>[INST] What is the clinical significance of RS1566186087 SNP, is it benign or pathogenic? [/INST] It is Pathogenic. </s> |
How long is the variation length for RS1566186087 SNP? | The variation length is 1 base pairs. | <s>[INST] How long is the variation length for RS1566186087 SNP? [/INST] The variation length is 1 base pairs. </s> |
What is the origin for RS1566186087 SNP? | The origin is germline. | <s>[INST] What is the origin for RS1566186087 SNP? [/INST] The origin is germline. </s> |
What is the type of genetic variation for RS1566186087 SNP? | The variation is a Insertion. | <s>[INST] What is the type of genetic variation for RS1566186087 SNP? [/INST] The variation is a Insertion. </s> |
What is the genetic molecular consequence for RS1566186087 SNP? | The resulting gene consequence is a frameshift variant. | <s>[INST] What is the genetic molecular consequence for RS1566186087 SNP? [/INST] The resulting gene consequence is a frameshift variant. </s> |
Which condition is asociated with RS1566233076 SNP? | Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1566233076 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1566233076 SNP. | <s>[INST] Which condition is asociated with RS1566233076 SNP? [/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1566233076 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1566233076 SNP. </s> |
In which chromosome is RS1566233076 SNP located? | It is located in the chromosome 13. | <s>[INST] In which chromosome is RS1566233076 SNP located? [/INST] It is located in the chromosome 13. </s> |
Which methods support the evidence found for the RS1566233076 SNP? | Associated methods are: clinical testing. | <s>[INST] Which methods support the evidence found for the RS1566233076 SNP? [/INST] Associated methods are: clinical testing. </s> |
What is the clinical significance of RS1566233076 SNP, is it benign or pathogenic? | It is Pathogenic. | <s>[INST] What is the clinical significance of RS1566233076 SNP, is it benign or pathogenic? [/INST] It is Pathogenic. </s> |
How long is the variation length for RS1566233076 SNP? | The variation length is 1 base pairs. | <s>[INST] How long is the variation length for RS1566233076 SNP? [/INST] The variation length is 1 base pairs. </s> |
What is the origin for RS1566233076 SNP? | The origin is germline. | <s>[INST] What is the origin for RS1566233076 SNP? [/INST] The origin is germline. </s> |
What is the type of genetic variation for RS1566233076 SNP? | The variation is a single nucleotide variant. | <s>[INST] What is the type of genetic variation for RS1566233076 SNP? [/INST] The variation is a single nucleotide variant. </s> |
What is the genetic molecular consequence for RS1566233076 SNP? | The resulting gene consequence is a nonsense. | <s>[INST] What is the genetic molecular consequence for RS1566233076 SNP? [/INST] The resulting gene consequence is a nonsense. </s> |
Which condition is asociated with DEL568222? | Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsDEL568222. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/DEL568222. | <s>[INST] Which condition is asociated with DEL568222? [/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsDEL568222. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/DEL568222. </s> |
In which chromosome is DEL568222 located? | It is located in the chromosome 13. | <s>[INST] In which chromosome is DEL568222 located? [/INST] It is located in the chromosome 13. </s> |
Which methods support the evidence found for the DEL568222? | Associated methods are: clinical testing. | <s>[INST] Which methods support the evidence found for the DEL568222? [/INST] Associated methods are: clinical testing. </s> |
What is the clinical significance of DEL568222, is it benign or pathogenic? | It is Pathogenic. | <s>[INST] What is the clinical significance of DEL568222, is it benign or pathogenic? [/INST] It is Pathogenic. </s> |
How long is the variation length for DEL568222? | The variation length is 176179 base pairs. | <s>[INST] How long is the variation length for DEL568222? [/INST] The variation length is 176179 base pairs. </s> |
What is the origin for DEL568222? | The origin is germline. | <s>[INST] What is the origin for DEL568222? [/INST] The origin is germline. </s> |
What is the type of genetic variation for DEL568222? | The variation is a Deletion. | <s>[INST] What is the type of genetic variation for DEL568222? [/INST] The variation is a Deletion. </s> |
Which condition is asociated with DEL568225? | Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsDEL568225. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/DEL568225. | <s>[INST] Which condition is asociated with DEL568225? [/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsDEL568225. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/DEL568225. </s> |
In which chromosome is DEL568225 located? | It is located in the chromosome 13. | <s>[INST] In which chromosome is DEL568225 located? [/INST] It is located in the chromosome 13. </s> |
Which methods support the evidence found for the DEL568225? | Associated methods are: clinical testing. | <s>[INST] Which methods support the evidence found for the DEL568225? [/INST] Associated methods are: clinical testing. </s> |
What is the clinical significance of DEL568225, is it benign or pathogenic? | It is Pathogenic. | <s>[INST] What is the clinical significance of DEL568225, is it benign or pathogenic? [/INST] It is Pathogenic. </s> |
How long is the variation length for DEL568225? | The variation length is 132 base pairs. | <s>[INST] How long is the variation length for DEL568225? [/INST] The variation length is 132 base pairs. </s> |
What is the origin for DEL568225? | The origin is germline. | <s>[INST] What is the origin for DEL568225? [/INST] The origin is germline. </s> |
What is the type of genetic variation for DEL568225? | The variation is a Deletion. | <s>[INST] What is the type of genetic variation for DEL568225? [/INST] The variation is a Deletion. </s> |
Which condition is asociated with RS1131690842 SNP? | Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1131690842 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1131690842 SNP. | <s>[INST] Which condition is asociated with RS1131690842 SNP? [/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1131690842 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1131690842 SNP. </s> |
In which chromosome is RS1131690842 SNP located? | It is located in the chromosome 13. | <s>[INST] In which chromosome is RS1131690842 SNP located? [/INST] It is located in the chromosome 13. </s> |
Which methods support the evidence found for the RS1131690842 SNP? | Associated methods are: clinical testing. | <s>[INST] Which methods support the evidence found for the RS1131690842 SNP? [/INST] Associated methods are: clinical testing. </s> |
What is the clinical significance of RS1131690842 SNP, is it benign or pathogenic? | It is Pathogenic. | <s>[INST] What is the clinical significance of RS1131690842 SNP, is it benign or pathogenic? [/INST] It is Pathogenic. </s> |
How long is the variation length for RS1131690842 SNP? | The variation length is 1 base pairs. | <s>[INST] How long is the variation length for RS1131690842 SNP? [/INST] The variation length is 1 base pairs. </s> |
What is the origin for RS1131690842 SNP? | The origin is germline. | <s>[INST] What is the origin for RS1131690842 SNP? [/INST] The origin is germline. </s> |
What is the type of genetic variation for RS1131690842 SNP? | The variation is a Deletion. | <s>[INST] What is the type of genetic variation for RS1131690842 SNP? [/INST] The variation is a Deletion. </s> |
What is the genetic molecular consequence for RS1131690842 SNP? | The resulting gene consequence is a frameshift variant. | <s>[INST] What is the genetic molecular consequence for RS1131690842 SNP? [/INST] The resulting gene consequence is a frameshift variant. </s> |
Which condition is asociated with RS1566174147 SNP? | Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1566174147 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1566174147 SNP. | <s>[INST] Which condition is asociated with RS1566174147 SNP? [/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1566174147 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1566174147 SNP. </s> |
In which chromosome is RS1566174147 SNP located? | It is located in the chromosome 13. | <s>[INST] In which chromosome is RS1566174147 SNP located? [/INST] It is located in the chromosome 13. </s> |
Which methods support the evidence found for the RS1566174147 SNP? | Associated methods are: clinical testing. | <s>[INST] Which methods support the evidence found for the RS1566174147 SNP? [/INST] Associated methods are: clinical testing. </s> |
What is the clinical significance of RS1566174147 SNP, is it benign or pathogenic? | It is Pathogenic. | <s>[INST] What is the clinical significance of RS1566174147 SNP, is it benign or pathogenic? [/INST] It is Pathogenic. </s> |
How long is the variation length for RS1566174147 SNP? | The variation length is 1 base pairs. | <s>[INST] How long is the variation length for RS1566174147 SNP? [/INST] The variation length is 1 base pairs. </s> |
What is the origin for RS1566174147 SNP? | The origin is germline. | <s>[INST] What is the origin for RS1566174147 SNP? [/INST] The origin is germline. </s> |
What is the type of genetic variation for RS1566174147 SNP? | The variation is a Duplication. | <s>[INST] What is the type of genetic variation for RS1566174147 SNP? [/INST] The variation is a Duplication. </s> |
What is the genetic molecular consequence for RS1566174147 SNP? | The resulting gene consequence is a frameshift variant. | <s>[INST] What is the genetic molecular consequence for RS1566174147 SNP? [/INST] The resulting gene consequence is a frameshift variant. </s> |
Which condition is asociated with RS1566197747 SNP? | Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1566197747 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1566197747 SNP. | <s>[INST] Which condition is asociated with RS1566197747 SNP? [/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1566197747 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1566197747 SNP. </s> |
In which chromosome is RS1566197747 SNP located? | It is located in the chromosome 13. | <s>[INST] In which chromosome is RS1566197747 SNP located? [/INST] It is located in the chromosome 13. </s> |
Which methods support the evidence found for the RS1566197747 SNP? | Associated methods are: clinical testing. | <s>[INST] Which methods support the evidence found for the RS1566197747 SNP? [/INST] Associated methods are: clinical testing. </s> |
What is the clinical significance of RS1566197747 SNP, is it benign or pathogenic? | It is Pathogenic. | <s>[INST] What is the clinical significance of RS1566197747 SNP, is it benign or pathogenic? [/INST] It is Pathogenic. </s> |
How long is the variation length for RS1566197747 SNP? | The variation length is 1 base pairs. | <s>[INST] How long is the variation length for RS1566197747 SNP? [/INST] The variation length is 1 base pairs. </s> |
What is the origin for RS1566197747 SNP? | The origin is germline. | <s>[INST] What is the origin for RS1566197747 SNP? [/INST] The origin is germline. </s> |
What is the type of genetic variation for RS1566197747 SNP? | The variation is a single nucleotide variant. | <s>[INST] What is the type of genetic variation for RS1566197747 SNP? [/INST] The variation is a single nucleotide variant. </s> |
What is the genetic molecular consequence for RS1566197747 SNP? | The resulting gene consequence is a nonsense. | <s>[INST] What is the genetic molecular consequence for RS1566197747 SNP? [/INST] The resulting gene consequence is a nonsense. </s> |
Which condition is asociated with RS1593544647 SNP? | Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1593544647 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1593544647 SNP. | <s>[INST] Which condition is asociated with RS1593544647 SNP? [/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1593544647 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1593544647 SNP. </s> |
In which chromosome is RS1593544647 SNP located? | It is located in the chromosome 13. | <s>[INST] In which chromosome is RS1593544647 SNP located? [/INST] It is located in the chromosome 13. </s> |
Which methods support the evidence found for the RS1593544647 SNP? | Associated methods are: clinical testing. | <s>[INST] Which methods support the evidence found for the RS1593544647 SNP? [/INST] Associated methods are: clinical testing. </s> |
What is the clinical significance of RS1593544647 SNP, is it benign or pathogenic? | It is Pathogenic. | <s>[INST] What is the clinical significance of RS1593544647 SNP, is it benign or pathogenic? [/INST] It is Pathogenic. </s> |
How long is the variation length for RS1593544647 SNP? | The variation length is 2 base pairs. | <s>[INST] How long is the variation length for RS1593544647 SNP? [/INST] The variation length is 2 base pairs. </s> |
What is the origin for RS1593544647 SNP? | The origin is germline. | <s>[INST] What is the origin for RS1593544647 SNP? [/INST] The origin is germline. </s> |
What is the type of genetic variation for RS1593544647 SNP? | The variation is a Deletion. | <s>[INST] What is the type of genetic variation for RS1593544647 SNP? [/INST] The variation is a Deletion. </s> |
What is the genetic molecular consequence for RS1593544647 SNP? | The resulting gene consequence is a splice acceptor variant. | <s>[INST] What is the genetic molecular consequence for RS1593544647 SNP? [/INST] The resulting gene consequence is a splice acceptor variant. </s> |
Which condition is asociated with RS1593412272 SNP? | Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1593412272 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1593412272 SNP. | <s>[INST] Which condition is asociated with RS1593412272 SNP? [/INST] Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1593412272 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1593412272 SNP. </s> |
In which chromosome is RS1593412272 SNP located? | It is located in the chromosome 13. | <s>[INST] In which chromosome is RS1593412272 SNP located? [/INST] It is located in the chromosome 13. </s> |
Which methods support the evidence found for the RS1593412272 SNP? | Associated methods are: clinical testing. | <s>[INST] Which methods support the evidence found for the RS1593412272 SNP? [/INST] Associated methods are: clinical testing. </s> |