sequence_alignment_aa_heavy
stringlengths 110
157
| cdr1_start_heavy
int64 133
563
| cdr1_end_heavy
int64 156
586
| cdr2_start_heavy
float64 208
638
| cdr2_end_heavy
float64 231
667
| cdr3_start_heavy
float64 346
782
| cdr3_end_heavy
float64 372
835
| sequence_alignment_aa_light
stringlengths 100
126
| cdr1_start_light
int64 133
822
| cdr1_end_light
int64 152
848
| cdr2_start_light
float64 204
900
⌀ | cdr2_end_light
float64 212
908
⌀ | cdr3_start_light
float64 321
1.02k
| cdr3_end_light
float64 350
1.05k
|
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
QVQLQESGPGLVKPSGTLSLTCTVSGHSISRSHWWSWVRQAPGKGLEWIGEIYHSGTTNYNPSLKSRVTISVDKSNNQFSLTLNSMTAADTALYYCARGREGNWNYILDSWGRGTLVTVSS | 168 | 194 | 246 | 266 | 381 | 422 | EVVLTQSPATLSLSPGERATLSCRASQSIGNYLAWYQQKPGQAPRLLIYDASNRATAVPARFSGGGSGTDFTLSISSLEPEDFAIYYCLHRSNWLTFGGGTKVEIK | 175 | 192 | 244 | 252 | 361 | 384 |
QVQLVESGGGVVQPGRSLTLSCAASGFTFSSYGLHWVRQAPGKGLEWVANIWYDGANKYYGDSVKGRFTISRDNSRNTLYLQMNSLTAEDTAVYYCARWIEYGSGKDAFDVWGQGTMVIVSS | 213 | 236 | 288 | 311 | 426 | 470 | DIQLTQSPSSLSASVGDRVTITCRASQYINNLLNWYQQKPGKAPKVLIYGASNLQSGVPSRFSGSGSGTDFTLTISGLQLEDFATYFCQQSYSTWTFGQGTKVEIK | 175 | 192 | 244 | 252 | 361 | 384 |
QVQLQESGPGLVKPSETLSLTCTVSGGSISSYYWSWIRQPPGKGLEWIGYIYYSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARDANSHGLGYWGQGTLVTVSS | 192 | 215 | 267 | 287 | 402 | 434 | DIQMTQSPSSLSASVGDRVTITCRASQGISNYLAWFQQKPGKAPKSLIYAASSLQSGVPSKFSGSGSGTDFTLTISSLQPEDFATYYCQQYNSYPWTFGQGTKVEIK | 172 | 189 | 241 | 249 | 358 | 384 |
QVTLRESGPALVKPTQTLTLTCTFSGFSLSTSGMCVSWIRQPPGKALEWLALIDWDDDKYYSTSLKTRLTISKDTSKNQVVLTMTNMDPVDTATYYCARQYYYDSSGYYYDWYFDLWGRGTLVTVSS | 152 | 181 | 233 | 253 | 368 | 424 | QSALTQPRSVSGSPGQSVTISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYDVSKRPSGVPDRFSGSKSGNTASLTISGLQAEDEADYYCCSYAGSYSVVFGGGTKLTVL | 175 | 201 | 253 | 261 | 370 | 399 |
QLQLQESGPGLVKPSETLSLTCTVSGGSISSSSYYWGWIRQPPGKGLEWIGSIYYSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARELLWELEEADWFDPWGQGTLVTVSS | 190 | 219 | 271 | 291 | 406 | 453 | DIQMTQSPSTLSASVGDRVTITCRASQSISSWLAWYQQKPGKAPKLLIYKASSLESGVPSRFSGSGSGTEFTLTISSLQPDDFATYYCQQYNSYWRTFGQGTKVEIK | 171 | 188 | 240 | 248 | 357 | 383 |
EVQLVESGGGVVQPGGSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSLISGDGGSTYYADSVKGRFTISRDNSKNSLYLQMNSLRTEDTALYYCAKDYYDSSGPDYWGQGTLVTVSS | 213 | 236 | 288 | 311 | 426 | 461 | DVVMTQSPLSLPVTLGQPASISCRSSQSLVYSDGNTYLNWFQQRPGQSPRRLIYKVSNRDSGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCMQGTHWPHTFGQGTKLEIK | 192 | 224 | 276 | 284 | 393 | 419 |
QVQLQESGPGLVKPSETLSLTCTVSGGSFRSYYWSWIRQPPGKGLEWIGYIYYSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCASTSAGYWGQGTLVTVSS | 207 | 230 | 282 | 302 | 417 | 437 | DIQMTQSPSSLSASVGDSVTITCRASQSIRNYLSWYHHKPGQAPKLLIYGASSLQSGVPSRFSGSGSGTDFTLTISSLQAEDFATYYCQQSDSLPWTFGQGTKVDIK | 179 | 196 | 248 | 256 | 365 | 391 |
DVQLLESGGGLVQPGGSLRLSCAASGFTFSNYALSWVRQAPGKGLEWVSSIIGSGGVTSYADSVRGRFTISRDNSKNTLYLQMDSLRTEDTAVYYCARDGGTPQYNLNYFYWGQGTLVTVSS | 212 | 235 | 287 | 310 | 425 | 469 | EIVLTQSPDTLSLSPGERATLSCRASQTITNNYLAWYRQKPGQAPRLLIYAASYRAAGIPDRFSGGGSGTDFTLTISRLEPEDFAMFYCHQYGTSPTFGQGTKVEIK | 175 | 195 | 247 | 255 | 364 | 387 |
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSKTDGGTTDYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTAVYYCTTDPLYYDFWSGPTLGDYWGQGTLVTVSS | 213 | 236 | 288 | 317 | 432 | 485 | EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWPPYTFGQGTKLEIK | 186 | 203 | 255 | 263 | 372 | 401 |
DVQLVESGGGLAQPGGSLRLSCAASGFTFSSYWMTWVRRAPGKGLEWVANINGNGKEYVESVKGRFTISRDNAKNSLFLQMNSLRVEDTAVYYCARDPYDHDSGSYGAFDVWGQGTPVTVSS | 212 | 235 | 287 | 304 | 419 | 469 | DVVMTQSPLSLPVTLGQPASISCRSSQSLVYKDGNTYLNWFQQRPGQSPRRLIYKVSNRDSGVPDRFSGSGSGTDFTLKISRVEAEDVGIYYCMQGTQWPYTFGQGTKLEIK | 200 | 232 | 284 | 292 | 401 | 427 |
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSKTDGGTTDYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTAVYYCTTAEGSFDYWGQGTLVTVSS | 213 | 236 | 288 | 317 | 432 | 458 | SYELTQPPSVSVSPGQTASITCSGDKLGDKYACWYQQKPGQSPVLVIYQDSKRPSGIPERFSGSNSGNTATLTISGTQAMDEADYYCQAWDSSGVFGGGTKLTVL | 294 | 311 | 363 | 371 | 480 | 503 |
QVQLQESGPGLVKPSQTLSLTCTVSGGSISSGSYYWSWIRQPAGKGLEWIGRIHISGSTNYNPSLKSRVTMSVDTSRNQFSLKLSSVTAADTAVYYCAASTGGYSSSWAEYYFGYWGQGTLVTVSS | 168 | 197 | 249 | 269 | 384 | 437 | DIVMTQSPDSLAVSLGERATINCKSSQNVLYSSNNKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSTPYTFGQGTKLEIK | 169 | 204 | 256 | 264 | 373 | 399 |
QITLKESGPTLVKPTQTLTLTCTFSGFSLSTSGVGVGWIRQPPGKALEWLALIYWDDDKRYSPSLKSRLTITKDTSKNQVVLTMTNMDPVDTATYYCAHQSPYYGSVAFDYWGQGTLVTVSS | 157 | 186 | 238 | 258 | 373 | 414 | QSVLTQPPSVSAAPGQKVTISCSGSSSNIGNNYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSLSAYVFGTGTKVTVL | 169 | 192 | 244 | 252 | 361 | 393 |
EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKFFAPVAYYYDSSEQGDYYGMDVWGQGTTVTVSS | 212 | 235 | 287 | 310 | 425 | 496 | AIRMTQSPSSFSASTGDRVTITCRASQGISSYLAWYQQKPGKAPKLLIYAASTLQSGVPSRFSGSGSGTDFTLTISCLQSEDFATYYCQQYYSYPLTFGGGTKVEIK | 172 | 189 | 241 | 249 | 358 | 384 |
EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKDVWYYDSSGYNDYWGQGTLVTVSS | 212 | 235 | 287 | 310 | 425 | 469 | EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWPWGAFGPGTKVDIK | 186 | 203 | 255 | 263 | 372 | 401 |
QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYYMHWVRQAPGQGLEWMGRINPNSGSTNYAQKFQGRVTMTSDTSTSTVYMELSSLRSEDTAVYYCARPALAYSINWSSLDWFDPWGQGTLVTVSS | 191 | 214 | 266 | 289 | 404 | 460 | DIQMTQSPATLSAFVGDRVTITCRASQSISSWLAWYQQKPGKAPKLLIQKASSLESGVPSRFSGSGSGTEFTLTISRLQPDDFATYYCQQYNTYSLTFGGGTKVEIK | 172 | 189 | 241 | 249 | 358 | 384 |
EVQLVESGGGFVHPGESLRLSCVASGFTFRPFWMNWVRQVPGKGLEWVATIGEDESRTWYLDSVKGRFTISRDNTKNSLYLQMDNLKAEDSAIYYCTRDPDTSSKVDFWGQGTLVTVSS | 212 | 235 | 287 | 310 | 425 | 460 | DVVMTQSPLSLPVTLGQPASISCRSSLSLVYSDGNAYLSWFQQRPGQSPRRLIYEVSKRDSGVPDRFSGSGSGTDFTLRISRVEAEDVGYYYCMQGTYRPPTFGQGTRLEIK | 169 | 201 | 253 | 261 | 370 | 396 |
DVKLLESGGSVVQPGGSLRLSCAASGFSFSSYAMSWVRQAPGRGLEWVSTITNSGTNTYFTDSVKGRFAISRDNSRETLYLQLNSLRAEDTAVYYCAKTWWGGTNENSVWFDPWGQGTLVTVSS | 212 | 235 | 287 | 310 | 425 | 475 | EIVLTQSPATLSLSPGERATLSCRASQSVSSFLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSSWPPITFGQGTRLEIK | 186 | 203 | 255 | 263 | 372 | 401 |
EVQLVESGGGLVQPGGSLRLSCAASGFTFSGYSMNWVRQAPGKGLEWVSYISSGGSPIHYADSVKGRFTISRDNANNSLYLQMNSLRDEDTAVYYCARDYDSSGRAFDYWGQGTLVTVSS | 212 | 235 | 287 | 310 | 425 | 463 | QSVLTQPPSVSAAPGQKVTISCSGSRSNMGIHYVSWYQQLPGTAPQLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSLSGVVFGGGTKLTVL | 169 | 192 | 244 | 252 | 361 | 393 |
EVQLVESGGGVVQPGGSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSLISGDGGSTYYADSVKGRFTISRDNSKNSLYLQMNSLRTEDTALYYCATGGSYGYYYGMDVWGQGTTVTVSS | 213 | 236 | 288 | 311 | 426 | 467 | EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSLWTFGQGTKVEIK | 223 | 243 | 295 | 303 | 412 | 438 |
EVQLVQSGAEVKKPGESLKISCKGSGYIFTNYWIGWVRQMPGKGLEWMGIIYPGDSDTRYSPSFQGQVTMSADKSVSTAYLQWSSLKASDTAMYYCARHGGHCNGGSCSRLPPGSYAMDGWGQGTTVTVSS | 192 | 215 | 267 | 290 | 405 | 476 | DIVMTQSPLSLPVTPGEPASISCRSSQSLLHSNGYNYLDWYLQKPGQAPQLLIYLGSNRASGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCMQALQTPYAFGQGTKLEIK | 174 | 206 | 258 | 266 | 375 | 401 |
EVQLVESGGGLVQPGRSLRLSCTASGFTFGDYAMSWVRQAPGKGLEWVGFIRSKAYGGTTEYAASVKGRFTISRDDSKSIAYLQMNSLKTEDTAVYYCTRDHPEWELRVSFDYWGQGTLVTVSS | 213 | 236 | 288 | 317 | 432 | 476 | DIQMTQSPSSLSASVGDRVTITCQASQDISNYLNWYQQKPGKAPKLLIYDASNLETGVPSRFSGSGSGTDFTFTISSLQPEDIATYYCQQYDNLPQTFGGGTKVEIK | 176 | 193 | 245 | 253 | 362 | 388 |
EVQLVESGGGLVQPGGSLKLSCAASGFTFSGSAMHWVRQASGKGLEWVGRIRSKANSYATAYAASVKGRFTISRDDSKNTAYLQMNSLKTEDTAVYYCTRGLIYDSSGSPFDYWGQGTLVTVSS | 213 | 236 | 288 | 317 | 432 | 476 | QTVVTQEPSLTVSPGGTVTLTCASSTGAVTSGYYPNWFQQKPGQAPRALIYSTSNKHSWTPARFSGSLLGGKAALTLSGVQPEDEAEYYCLLYYGGAVVFGGGTKLTVL | 167 | 193 | 245 | 253 | 362 | 388 |
QITLKESGPTLVKPTQTLTLTCTFSGFSLSTSGVGVGWIRQPPGKALEWLALIYWNDDKRYSPSLKSRLTITKDTSKNQVVLTMTNMDPVDTATYYCAHRPLLWFGEASGRWFDPWGQGTLVTVSS | 157 | 186 | 238 | 258 | 373 | 426 | DIQMTQSPSSVSASVGDRVTITCRASQGISSWLAWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQANSFPFTFGPGTKVDIK | 172 | 189 | 241 | 249 | 358 | 384 |
QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYAINWVRQAPGQGLEWMGGIIPVFDTTNYAQKFQGRVTITADKSTTTAYMELSSLRSEDAAMYYCARAADRGTYYNYYGMDVWGQGTTVTVSS | 181 | 204 | 256 | 279 | 394 | 444 | EIVLTQSPGSLSLSPGERATLSCRASQSVSRNYLAWYQQKPGQAPRLLIYGASSRATGISDRFSGSGSGTDFTLTINRLEPEDFAVYHCQQYGGLPWTFGQGTKLEIK | 183 | 203 | 255 | 263 | 372 | 398 |
QVQLQESGPGLVKPSQTLSLTCTVSGGSISSGSYYWSWIRQPAGKGLEWIGRIYTSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARGGELSLIYYYYGMDVWGQGTTVTVSS | 168 | 197 | 249 | 269 | 384 | 434 | SSELTQDPAVSVALGQTVRITCQGDSLRSYYASWYQQKPGQAPVLVIYGKNNRPSGIPDRFSGSSSGNTASLTITGAQAEDEADYYCNSRDSSGNHLEVFGTGTKVTVL | 173 | 190 | 242 | 250 | 359 | 394 |
QVQLQESGPGLVKPSETLSLTCTVSGGSVSSSNYYWTWLRQSPGKGLEWIGYVYYTGTTNYNPSLETRVIISVDTSKNQFSLRLNSVTAADTAVYYCARDEGLSGPRDGGFDPWGQGTLVTVSS | 170 | 199 | 251 | 271 | 386 | 433 | EIVMTQTPLSSPVTLGQPASISCRSSQSLLHSDGNTYLSWLQQRPGQPPRLLIYKISNRFSGVPDRFSGSGAGTDFTLKISRVEAEDVGVYYCMQARQFPYTFGQGTKLEIK | 169 | 201 | 253 | 261 | 370 | 396 |
QVQLVESGGGLVKPGGSLRLSCAASGFTFSDYYMSWIRQAPGKGLEWVSYISSSGSTIYYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARDPQWLARFDYWGQGTLVTVSS | 213 | 236 | 288 | 311 | 426 | 461 | QSVLTQPPSASGTPGQRVTISCSGSSSNIGSNTVNWYQQLPGTAPKLLIYSNNQRPSGVPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDDSLNGRVVFGGGTKLTVL | 180 | 203 | 255 | 263 | 372 | 407 |
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSKTDGGTTDYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTAVYYCTTDPSKNCGGDCYSYYYYYYMDVWGKGTTVTVSS | 213 | 236 | 288 | 317 | 432 | 500 | DIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTPKTFGQGTKVEIK | 172 | 189 | 241 | 249 | 358 | 384 |
QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYGISWVRQAPGQGLEWMGWISAYNGNTNYAQKLQGRVTMTTDTSTSTAYMELRSLRSDDTAVYYCARTRLAAYYYYGMDVWGQGTTVTVSS | 187 | 210 | 262 | 285 | 400 | 444 | DIVMTQSPLSLPVTPGEPASISCRSSQSLLHSNGYNYLDWYLQKPGQSPQLLIYLGSNRASGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCMQALQTLWTFGQGTKVEIK | 174 | 206 | 258 | 266 | 375 | 401 |
QVQLQESGPGLVKPSGTLSLTCAVSGGSISSNNWWNWVRQPPGKGLEWIGEIYHTGRTNYNPSLKSRVTISVDKSKNQFSLRLSSVTAADTAVYYCARGGGPYFDYWGQGTLVTVSS | 172 | 198 | 250 | 270 | 385 | 414 | EIVLTQSPGTLSLSPGERATLSCRASQSVISDYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSIMYTFGQGTKLEIK | 175 | 195 | 247 | 255 | 364 | 393 |
EVQLAESGGGLVQPGGSLRLSCAASGFTFSNYWMNWVRQAPGKGLEWVANIKQDGNTIYYVDSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCAKGGLAPGDYWGQGTLVTVSS | 212 | 235 | 287 | 310 | 425 | 454 | QSVLTQPPSASGTPGQRVTISCSGSNSNIGNNPVNWYQHLPGTAPKLLIYTNNERPSGVPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDGSLSGYIFGTGTKVTVL | 180 | 203 | 255 | 263 | 372 | 404 |
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSRTDGGTTDYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTGVYYCTTHYYDRSGYYPGYFHHWGQGTLVTVSS | 213 | 236 | 288 | 317 | 432 | 482 | DIVMTQSPDSLAVSLGERATINCKSGHSVLYSSNSKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSPPLTFGGGTKVEIK | 169 | 204 | 256 | 264 | 373 | 399 |
QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYTISWVRQAPGQGLEWMGRIIPILGIANYAQKFQGRVTITADKSTSTAYMELSSLRSEDTAVYYCASDPQSHYDSSGYYHWGQGTLVTVSS | 184 | 207 | 259 | 282 | 397 | 441 | DIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTRITFGQGTRLEIK | 174 | 191 | 243 | 251 | 360 | 386 |
QITLKESGPTLVKPTQTLTLTCTFSGFSLSTSGVGVGWIRQPPGKALEWLALIYWNDDKRYSPSLKSRLTITKDTSKNQVVLTMTNMDPVDTATYYCAHFNYYDSSGYWTPGRGYFDYWGQGTLVTVSS | 153 | 182 | 234 | 254 | 369 | 431 | QSALTQPRSVSGSPGQSVTISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYDVSKRPSGVPDRFSGSKSGNTASLTISGLQAEDEADYYCCSYAGSYSVVFGGGTKLTVL | 175 | 201 | 253 | 261 | 370 | 399 |
EVRLAESGCSLVQPGGSLSLSCAASGFSLSGYWMHWVRRVPGKGLVWVARISSDGSSTEYADAVKGRFTISRDNAKNTLFLQMNSLRAEDTAVYHCTRGGSVDVIRGVFDSWGQGALVTVSS | 201 | 224 | 276 | 299 | 414 | 458 | DIVMTQSPDSMAVSLGERATINCKSSQSVLYSPNNKNDLTWYQHKPGQPPRLLIYWASTRASGVPDRFSGSGSGTDFTLTISNLQAEDGAIYYCQQHKSDPYTFGQGTKLEIK | 169 | 204 | 256 | 264 | 373 | 399 |
EVQLAEAGGGLVQPGGSRRLSCAASGFTFGSYWVSWVRQAPGKGLEWVANINQDGSQKHFVDSVKGRFTISRDSAKNSVYLQIDSLRAEDTALYYCAVDSSGSYGWDSWGQGTLVTVSS | 212 | 235 | 287 | 310 | 425 | 460 | DIQMTQSPSSLSASVGDRVTITCRASQSITRYLNWYQQKPGKAPKLLIYGTSSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSDSVPRTFGQGTKVEIK | 175 | 192 | 244 | 252 | 361 | 387 |
EVQLVESGGGLVQPGGSLRLSCAASGFTFSTYWMSWVRQAPGKGLEWVANIKQDESEKYYVDSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARSTYCTSTSCYHYYYYGMDVWGQGTTVTVSS | 212 | 235 | 287 | 310 | 425 | 487 | DIQMTQSPSTLSASVGDRVTITCRASQSISSWLAWYQQKPGKAPNLLIYKASSLESGVPSRFSGSGSGTEFTLTISSLQPDDFATYYCQQYNSYPWTFGQGTKVEIK | 172 | 189 | 241 | 249 | 358 | 384 |
QLQLQESGPGLVKPSETLSLTCTVSGGSISSSSYYWGWIRQPPGKGLEWIGSIYYSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARLPSPYDSSGYPDAFDIWGQGTMVTVSS | 204 | 233 | 285 | 305 | 420 | 473 | EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWPLTFGGGTKVEIK | 186 | 203 | 255 | 263 | 372 | 398 |
EVQLVESGGGVVQPGGSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSLISGDGGSTYYADSVKGRFTISRDNSKNSLYLQMNSLRTEDTALYYCAKDDYWGQGTLVTVSS | 213 | 236 | 288 | 311 | 426 | 440 | EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWPPVTFGPGTKVDIK | 186 | 203 | 255 | 263 | 372 | 401 |
QVQLVQSGSELKKPGASVKVSCKASGYTFTSYAMNWVRQAPGQGLEWMGWINTNTGNPTYAQGFTGRFVFSLDTSVSTAYLQISSLKAEDTAVYYCARADMIDYGVSLNWFDPWGQGTLVTVSS | 182 | 205 | 257 | 280 | 395 | 445 | SYVLTQPPSVSVAPGKTARITCGGNNIGSKSVHWYQQKPGQAPVLVIYYDSDRPSGIPERFSGSNSGNTATLTISRVEAGDEADYYCQVWDSSSDHYVVFGGGTKLTVL | 173 | 190 | 242 | 250 | 359 | 394 |
QVQLQESGPGLVKPSETLSLTCTVSGGSISSYYWSWIRQPPGKGLEWIGYIYYSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARFMPQNFYYYYGMDVWGQGTTVTVSS | 168 | 191 | 243 | 263 | 378 | 425 | QTVVTQEPSLTVSPGGTVTLTCASSTGAVTSGYYPNWFQQKPGQAPRALIYSTSNKHSWTPARFSGSLLGGKAALTLSGVQPEDEAEYYCLLYYGGVWVFGGGTKLTVL | 167 | 193 | 245 | 253 | 362 | 388 |
QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYYMHWVRQAPGQGLEWMGIINPSGGSTSYAQKFQGRVTMTRDTSTSTVYMELSSLRSEDTAVYYCASPGGFGELLYPRGYYGMDVWGQGTTVTVSS | 191 | 214 | 266 | 289 | 404 | 463 | DIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTPYTFGQGTKLEIK | 175 | 192 | 244 | 252 | 361 | 387 |
QLQLQESGPGLVKPSETLSLTCTVSGGSISSSSYYWGWIRQPPGKGLEWIGSIYYSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCASWYYDILTGYYNWGQGTLVTVSS | 175 | 204 | 256 | 276 | 391 | 429 | QSALTQPASVSGSPGQSITISCTGTSSDVGSYNLVSWYQQHPGKAPKLMIYEGSKRPSGVSNRFSGSKSGNTASLTISGLQAEDEADYYCCSYAGSSVVFGGGTKLTVL | 171 | 197 | 249 | 257 | 366 | 392 |
QVQLVESGGGLVKPGGSLRLSCAASGFTFSDYYMSWIRQAPGKGLEWVSYISSSGSTIYYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARSYYDMHYYYYGMDVWGQGTTVTVSS | 213 | 236 | 288 | 311 | 426 | 473 | DIQMTQSPSTLSASVGDRVTITCRASQSISSWLAWYQQKPGKAPKLLIYKASSLESGVPSRFSGSGSGTEFTLTISSLQPDDFATYYCQQYNSYPYTFGQGTKLEIK | 172 | 189 | 241 | 249 | 358 | 384 |
EVQLVESGGGLVQPGRSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSGISWNSGSIGYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTALYYCAKRLGLCSSTSCYSFQGDAFDIWGQGTMVTVSS | 218 | 241 | 293 | 316 | 431 | 496 | QSVLTQPPSASGTPGQRVTISCSGSSSNIGSNTVNWYQQLPGTAPKLLIYSNNQRPSGVPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDDSLNGWVFGGGTKLTVL | 180 | 203 | 255 | 263 | 372 | 404 |
QITLKESGPTLVKPTQTLTLTCTFSGFSLSTSGVGVGWIRQPPGKALEWLALIYWDDDKRYSPSLKSRLTITKDTSKNQVVLTMTNMDPVDTATYYCAHAPMVRGVMGAFDIWGQGTMVTVSS | 158 | 187 | 239 | 259 | 374 | 418 | QSVLTQPPSASGTPGQRVTISCSGSSSNIGSNTVNWYQQLPGTAPKLLIYSNNQRPSGVPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDDSLNGPVFGGGTKLTVL | 198 | 221 | 273 | 281 | 390 | 422 |
EVQLVESGGGLVQPGRSLRLSCTASGFTFGDYAMSWVRQAPGKGLEWVGFIRSKAYGGTTEYAASVKGRFTISRDDSKSIAYLQMNSLKTEDTAVYYCTREGGATGDAFDIWGQGTMVTVSS | 213 | 236 | 288 | 317 | 432 | 470 | QSVLTQPPSVSGAPGQRVTISCTGSSSNIGAGYDVHWYQQLPGTAPKLLIYGNSNRPSGVPDRFSGSKSGTSASLAITGLQAEDEADYYCQSYDSSLSGHVVFGGGTKLTVL | 184 | 210 | 262 | 270 | 379 | 414 |
EVHLVESGGGLVQPGGSLRLSCAASGFIFSSYGMHWVRQAPGKGLVWVSRINSDGSITNYADSVKGRFTISRDNAKNTLSLQMNSLRAEDTAVYFCTRSNKGHCSGVGCYLGPEYWGQGTLVTVSS | 242 | 265 | 317 | 340 | 455 | 511 | QSVLTQPPSASGTPGRRVTISCSGSSSNVGSNTVNWYQHLPGMAPKLLIYSNNQRPSGVPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDDSLNGWVFGGGTKLTVL | 180 | 203 | 255 | 263 | 372 | 404 |
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGHIKSKTDGGTTDYAAPVKGRFTISRDGSKNTLYLQMNSLKTEDTAIYYCTTDTSWGPYYFDYWGQGTLVTVSS | 213 | 236 | 288 | 317 | 432 | 470 | QSALTQPASVSGSPGQSITFSCTGTSSDVGSYNPVSWYQQHPGKAPKLMIYEDSKRPSGVSNRFSGSKSGNTASLTISGLQAEDEADYYCCSYAGTSTWVFGGGTKLTVL | 171 | 197 | 249 | 257 | 366 | 395 |
QLQLQESGSGLVKPSQTLSLTCAVSGGSISSGGYSWSWIRQPPGKGLEWIGYIYHSGSTYYNPSLKSRVTISVDRSKNQFSLKLSSVTAADTAVYYCARVVSLVKAFDIWGQGTMVTVSS | 168 | 197 | 249 | 269 | 384 | 419 | QSALTQPASVSGSPGQSITISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYEVSNRPSGVSNRFSGSKSGNTASLTISGLQAEDEADYYCSSYTSSSTDVFGTGTKVTVL | 174 | 200 | 252 | 260 | 369 | 398 |
EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKGTYCSGGSCYSPKRTVEKDYYYYGMDVWGQGTTVTVSS | 212 | 235 | 287 | 310 | 425 | 511 | DIVMTQSPLSLPVTPGEPASISCRSSQSLLHSNGYNYLDWYLQKPGQSPQLLIYLGSNRASGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCMQALQTPWTFGQGTKVEIK | 175 | 207 | 259 | 267 | 376 | 402 |
EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKNIPLPGIAVAGSFDYWGQGTLVTVSS | 212 | 235 | 287 | 310 | 425 | 475 | EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWPPLTFGGGTKVEIK | 186 | 203 | 255 | 263 | 372 | 401 |
EVQLVESGGGLVQPGGSLRLSCVASGFSTSNYWMGWVRQAPGKGLEWVANIKQDGSEKYYGDSVKGRFTISRDNAKNSLYLQINSLRAEDTAVYYCARAHSGGIGARLYWGQGTLVTVSS | 212 | 235 | 287 | 310 | 425 | 463 | EIVMTQSPATLSVSPGERATLSCRASQSVSSNLAWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTEFTLTISSLQSEDFAVYYCHQYDNWPWTSGQGTKVEIK | 175 | 192 | 244 | 252 | 361 | 387 |
EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAATLVPAATQSPDYWGQGTLVTVSS | 212 | 235 | 287 | 310 | 425 | 466 | AIRMTQSPSSFSASTGDRVTITCRASQGISSYLAWYQQKPGKAPKLLIYAASTLQSGVPSRFSGSGSGTDFTLTISCLQSEDFATYYCQQYYSYPPTFGQGTKLEIK | 172 | 189 | 241 | 249 | 358 | 384 |
QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYAMHWVRQAPGKGLEWVAVISYDGSNKYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARVGSSGWYNGDYYYYGMDVWGQGTTVTVSS | 200 | 223 | 275 | 298 | 413 | 472 | DIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTPLTFGGGTKVEIK | 180 | 197 | 249 | 257 | 366 | 392 |
EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKDRFLHAGIAAAVDYWGQGTLVTVSS | 206 | 229 | 281 | 304 | 419 | 466 | DIQMTQSPSSLSASVGDRVTITCQASQDISNYLNWYQQKPGKAPKLLIYDASNLETGVPSRFSGSGSGTDFTFTISSLQPEDIATYYCQQYDNSLTFGGGTKVEIK | 176 | 193 | 245 | 253 | 362 | 385 |
QVQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAPGQGLEWMGWINPNSGGTNYAQKFQGRVTMTRDTSISTAYMELSRLRSDDTAVYYCARGLLAAAGNYYYYGMDVWGQGTTVTVSS | 195 | 218 | 270 | 293 | 408 | 461 | SYVLTQPPSVSVAPGQTARITCGGNNIGSKSVHWYQQKPGQAPVLVVYDDSDRPSGIPERFSGSNSGNTATLTISRVEAGDEADYYCQVWDSSSDLGGVFGGGTKLTVL | 258 | 275 | 327 | 335 | 444 | 479 |
QVQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAPGQGLEWMGWINPNSGGTNYAQKFQGWVTMTRDTSISTAYMELSRLRSDDTAVYYCARARNHLKYSSSSSHYYYYGMDVWGQGTTVTVSS | 197 | 220 | 272 | 295 | 410 | 478 | QTVVTQEPSFSVSPGGTVTLTCGLSSGSVSTSYYPSWYQQTPGQAPRTLIYSTNTRSSGVPDRFSGSILGNKAALTITGAQADDESDYYCVLYMGSGIWVFGGGTKLTVL | 178 | 204 | 256 | 264 | 373 | 402 |
EVQLVESGGGLVQPGRSLRLSCTASGFTFGDYAMSWVRQAPGKGLEWVGFIRSKAYGGTTEYAASVKGRFTISRDDSKSIAYLQMNSLKTEDTAVYYCTRGPYGDSTYYYYGMDVWGQGTTVTVSS | 213 | 236 | 288 | 317 | 432 | 482 | QPVLTQPPSASASLGASVTLTCTLSSGYSNYKVDWYQQRPGKGPRFVMRVGTGGIVGSKGDGIPDRFSVLGSGLNRYLTIKNIQEEDESDYHCGADHGSGSNFVFVFGGGTKLTVL | 170 | 190 | 242 | 265 | 374 | 412 |
QVQLQESGPGLVKPSQTLSLTCTVSGGSISSGSYYWSWIRQPAGKGLEWIGRIYTSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARAPRARSSRVDYFDYWGQGTLVTVSS | 179 | 208 | 260 | 280 | 395 | 442 | VIWMTQSPSLLSASTGDRVTISCRMSQGISSYLAWYQQKPGKAPELLIYAASTLQSGVPSRFSGSGSGTDFTLTISCLQSEDFATYYCQQYYSFPYTFGQGTKLEIK | 172 | 189 | 241 | 249 | 358 | 384 |
QVQLVQSGAEVKKPGASVKVSCKASNYPFTTYGISWVRQAPGQGLEWMGWINAYNGNTNFAQKLQDRVTMTTDTSTSTAYMELRSLRSDDTAVYYCARDGSGTWNDYWGQGTLVAVSS | 192 | 215 | 267 | 290 | 405 | 437 | QLVLTQSPSASASLGASVKLTCILSSGHSSYAIAWHQQQPEKGPRYLMKVNRDGSHSKGDGIPDRFSGSSSGAERYLTISSLQSEDEADYYCQTWGTGIQVFGGGTKLTVL | 158 | 178 | 230 | 250 | 359 | 385 |
QVQLQESGPGLVKPSETLSLTCTVSGGSISSYYWSWIRQPPGKGLEWIGYIYYSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARAGPAYCSGGSCYSEPYHYYYYGMDVWGQGTTVTVSS | 170 | 193 | 245 | 265 | 380 | 460 | SYELTQPPSVSVSPGQTASITCSGDKLGDKYACWYQQKPGQSPVLVIYQDSKRPSGIPERFSGSNSGNTATLTISGTQAMDEADYYCQAWDSSTAVVFGGGTKLTVL | 219 | 236 | 288 | 296 | 405 | 434 |
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSKTDGGTTDYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTAVYYCTTVTRGYRSNWFDPWGQGTLVTVSS | 213 | 236 | 288 | 317 | 432 | 473 | SYVLTQPPSVSVAPGQTARITCGGNNIGSKSVHWYQQKPGQAPVLVVYDDSDRPSGIPERFSGSNSGNTATLTISRVEAGDEADYYCQVWDSSSDHPVFGGGTKLTVL | 267 | 284 | 336 | 344 | 453 | 485 |
EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYSMNWVRQAPGKGLEWVSSISSSSSYIYYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARLLYDEWEGYWGQGTLVTVSS | 212 | 235 | 287 | 310 | 425 | 457 | QLVLTQSPSASASLGASVKLTCTLSSGHSSYAIAWHQQQPEKGPRYLMKLNSDGSHSKGDGIPDRFSGSSSGAERYLTISSLQSEDEADYYCQTWGTGIVFGGGTKLTVL | 158 | 178 | 230 | 250 | 359 | 382 |
QVQLQESGPGLVKPSQTLSLTCTVSGGSISSGGYYWSWIRQHPGKGLEWIGYIYYSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARGDYGDPPGYYGMDVWGQGTTVTVSS | 192 | 221 | 273 | 293 | 408 | 455 | AIRMTQSPSSFSASTGDRVTITCRASQGISSYLAWYQQKPGKAPKLLIYAASTLQSGVPSRFSGSGSGTDFTLTISCLQSEDFATYYCQQYYSYPWTFGQGTKVEIK | 172 | 189 | 241 | 249 | 358 | 384 |
EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKVWGRLLWFGSPFDYWGQGTLVTVSS | 212 | 235 | 287 | 310 | 425 | 472 | EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSPWTFGQGTKVEIK | 183 | 203 | 255 | 263 | 372 | 398 |
EVQLMESGGGVVQPGGSLRLSCAASGFTFSWFWMSWVRQAPGKGLEWVASIKPDGSEKYYVESVKGRLIISRDNANNEMYLQMNSLRAEDTAVYYCATEDKSAFESWGQGTLVTVSS | 212 | 235 | 287 | 310 | 425 | 454 | QSVLMQPPSVSAAPGQTVTISCSGSSSSIGNNFVSWYQLLPGAAPKLLIYENNKRPSGVPDRFSASKSGTSATLGITGLQTGDEADYYCGSWDRKVLGTGTKVTVL | 169 | 192 | 244 | 252 | 361 | 381 |
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSKTDGGTTDYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTAVYYCTTDTLIAAAGARHLLYGMDYWGQGTLVTVSS | 213 | 236 | 288 | 317 | 432 | 491 | DIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTPLTFGGGTKVEIK | 176 | 193 | 245 | 253 | 362 | 388 |
EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKDAAGTLWDTAMEGLGYYYYYYMDVWGKGTTVTVSS | 212 | 235 | 287 | 310 | 425 | 502 | EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGISDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSRGTFGQGTKVEIK | 191 | 211 | 263 | 271 | 380 | 406 |
EVQLVDSGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGHIKSKTDGGTTDYAAPVKGRFTISRDDSKNTLFLQMNSLKTEDTAVYYCTTGDNWNYFYWGRGTLVTVSS | 213 | 236 | 288 | 317 | 432 | 461 | SYELTQPPSVSVSPGQTASITCSGDNLGNKYASWYQQKPGQSPVLVIYQDNKRPSGIPERFSGSNSGNTATLTISGTQAMDEADYYCQAWDSSTARFGGGTKLTVL | 170 | 187 | 239 | 247 | 356 | 382 |
EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYSMNWVRQAPGKGLEWVSSISSSSSYIYYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARALYGDSVNYYYYGMDVWGQGTTVTVSS | 212 | 235 | 287 | 310 | 425 | 478 | QSVLTQPPSVSAAPGQKVTISCSGSSSNIGNNYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSLSAGVFGGGTKLTVL | 169 | 192 | 244 | 252 | 361 | 393 |
QVQLQESGPGLVKPSETLSLTCTVSGGSITSDYWTWIRQPPGKGLEWIGYIYYSGNINYNPSLRSRVTISVDMSKNQFSLKLSSVTAADTAVYYCARYQYGAGPFDIWGQGTMVTVSS | 170 | 193 | 245 | 265 | 380 | 415 | DIQMTQSPPTLSASVGDRATITCRASQSISNRLAWYQQKPGKAPKLLIYKASTLESGVPSRFSGSGSGTEFTLTITSLQPDDFATYYCQQYDNYFRTFGQGTKVEIK | 172 | 189 | 241 | 249 | 358 | 384 |
EVQLVESGGGLVQPGESLRLSCAASGFTFSDYSMAWVRQAPGKGLEWVANINQDGTKKNHLGSVTGRFAISRDNAKNSLYLQMNSLRAEDTAVYYCARDLGGRYDFWSHWGQGTLVAVSS | 212 | 235 | 287 | 310 | 425 | 463 | DIQMTQSPSSVSASIGDRVTITCRASHDIDGWLAWYQQKPGKAPKLLVYAASRLQSGVPSRFSGSGSGTDFALTISRLQPEDFATYYCHQANSFPLTFGGGTKVEIK | 172 | 189 | 241 | 249 | 358 | 384 |
QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYAMHWVRQAPGKGLEWVAVISYDVGDKHYTDSVKGRFTISRDNSKNTLYLQMNSLRAEDTGVYYCARDTSAPFDSWGQGTLVTVSS | 200 | 223 | 275 | 298 | 413 | 442 | DIQMTQSPSSLSASVGDRVTITCRASQGINSYLAWFQQKPGKAPKSLIYAASTLQSGVPSKFSGSGSGTDFTLTISSLQPEDFATYYCQQYKSYPRTFGQGTKVEIK | 172 | 189 | 241 | 249 | 358 | 384 |
QVQLQESGPGLVKPSETLSLTCTVSGGSISSYYWSWIRQPPGKGLEWIGYIYYSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARVCSSTSCYPKKDGWFDPWGQGTLVTVSS | 170 | 193 | 245 | 265 | 380 | 436 | EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSPSTFGQGTKLEIK | 183 | 203 | 255 | 263 | 372 | 398 |
QLQLQESGPGLVKSSETLSLTCTVSGGSISSSSYYWGWIRQPPGKGLEWIGSIYYSGSSYHNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYFCASLTTVTTFGYWGQGTLVTVSS | 174 | 203 | 255 | 275 | 390 | 422 | QSVLTQPPSVSAAPGQKVTISCSGSSSNIGNNYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSVSAWVFGGGTKLTVL | 169 | 192 | 244 | 252 | 361 | 393 |
EVQLVESGGGLVQPGRSLRLSCAASGFTFGNYAMYWVRQIPGKGLEWVSGISWNSDTIGYADSVKGRFTISRDNAKNSLYLQMNSLRVEDTAMYYCAKVGGLGSYYYTPIESWGQGTLVTVSS | 228 | 251 | 303 | 326 | 441 | 488 | DIQLTQSPSFLSASVGDRVTITCRASQGISSYLAWYQQKPGKAPKLLIYAASTLQSGVPSRFSGSGSGTEFTLTISSLQPEDFATYYCQQLNSYPRTFGQGTKVEIK | 172 | 189 | 241 | 249 | 358 | 384 |
EVQLMESGGHLVQPGGSLKLSCAASGFTFSDYSMDWVRQAPGKGLEWVARMRDKAYTYTTQYAASVKGRFTISRDDSKSLVYLQMNSLKTEDTAVYYCSRDSYGNPDYWGQGTLVTVSS | 213 | 236 | 288 | 317 | 432 | 461 | DIQMTQSPSSLSASVGDRVTITCRASQDIRNDLGWYQQKPGKAPKRLIYATSTLQSGVPSRFSGSGSGTEFTLTITSLQPEDFATYYCLQYNTYPGTFGQGTKVEIK | 181 | 198 | 250 | 258 | 367 | 393 |
QVQLQQSGPGLVKPSQTLSVTCAISGDSVSSNTATWNWIRQSPSRGLEWLGRTYFRSKWFYDYALSVKSRITINADTSRSQFSLQLNSVTPEDTAVYYCARERRFTFFGVVTRTNWYFDLWGRGTLVTVSS | 188 | 217 | 269 | 295 | 410 | 472 | SSELTQDPAVSVALGQTVRITCQGDSLRNYYASWYQQKPGQAPLLVIYGENYRPSGIPDRFSGSSSGNTASLTITGAQAEDEADYYCNSRDSSGNVVVFGGGTKLTVL | 173 | 190 | 242 | 250 | 359 | 391 |
EVQLVESGGGLVQPGRSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSGISWNSGSIGYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTALYYCAKDESSGWYVFDYWGQGTLVTVSS | 217 | 240 | 292 | 315 | 430 | 468 | QSALTQPRSVSGSPGQSVTISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYDVSKRPSGVPDRFSGSKSGNTASLTISGLQAEDEADYYCCSYAGSYTWVFGGGTKLTVL | 175 | 201 | 253 | 261 | 370 | 399 |
EVQLVESGGGLIKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRFMSKTDGGTTDYAAPVKGRFTVSRDDSKNTLYLQMNSLKTEDTAVYYCTAGTGRTDHDYWGQGTLVTVSS | 213 | 236 | 288 | 317 | 432 | 464 | DIVMTQSPDSLAVSLGERATINCKSSQSVLYSSNNKNFLAWYQQKAGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYMTPLTFGGGTKVEIK | 169 | 204 | 256 | 264 | 373 | 399 |
QVQLQESGPGLVKPSETLSLTCTVSGYSISSGYYWGWIRQPPGKGLEWIGSIYHSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARDLNSGLIDYWGQGTLVTVSS | 173 | 199 | 251 | 271 | 386 | 418 | QSVLTQPPSASGTPGQRVTISCSGSSSNIGSNYVYWYQQLPGTAPKLLIYRNNQRPSGVPDRFSGSKSGTSASLAISGLRSEDEADYYCAAWDDSLSVLFGGGTKLTVL | 180 | 203 | 255 | 263 | 372 | 401 |
EVQLVESGGGLIQPGGSLRLSCAASGFTVSSNYMSWVRQAPGKGLEWVSVIYSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARLRRDGYNSWDWFDPWGQGTLVTVSS | 242 | 265 | 317 | 337 | 452 | 499 | DIQMTQSPSTLSASVGDRVTITCRASQSISSWLAWYQQKPGKAPKLLIYKASSLESGVPSRFSGSGSGTEFTLTISSLQPDDFATYYCQHRHTFGQGTKLEIK | 172 | 189 | 241 | 249 | 358 | 372 |
EVQLVESGGGLVQPGGSLRLSCAASGFTVSSNYMSWVRQAPGKGLEWVSVIYSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARANRGAGFSTVPMRDKGFFAFDIWGQGTMVTVSS | 212 | 235 | 287 | 307 | 422 | 493 | EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWPPGITFGQGTRLEIK | 175 | 192 | 244 | 252 | 361 | 393 |
QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYDINWVRQATGQGLEWMGWMNPNSGNTGYAQKFQGRVTMTRNTSISTAYMELSSLRSEDTAVYYCARFTPKEPDYFDYWGQGTLVTVSS | 191 | 214 | 266 | 289 | 404 | 442 | DIQMTQSPSSLSASVGDRVTITCRASQGIRNDLGWYQQKPGKAPKRLIYAASSLQSGVPSRFSGSGSGTEFTLTISSLQPEDFATYYCLQHNSYPWTFGQGTKVEIK | 165 | 182 | 234 | 242 | 351 | 377 |
QVQLVQSGSELKEPGASVKVSCRASGYSFTSYAVNWVRLAPGQGLEWMGWINTDTKNPTYARDFTGRFVFSLDTSVDTAYLQISSLRAEDTAVYYCARHSAALGLPDYWGQGTLVTVSS | 182 | 205 | 257 | 280 | 395 | 430 | DIQMTQSPSSLSASVGDRVTITCRASQPFSNYLAWYQQKPGKVPQLLIYSASTLQSGVPSRFSGSGSWTTFTLTINNLQPEDAATYYCQKHNSAPLTFGQGTKVEIE | 172 | 189 | 241 | 249 | 358 | 384 |
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSKTDGGTTDYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTAVYYCTTDRVVVVAATGYYYYGMDVWGQGTTVTVSS | 213 | 236 | 288 | 317 | 432 | 491 | SYELTQPPSVSVSPGQTASITCSGDKLGDKYACWYQQKPGQSPVLVIYQDSKRPSGIPERFSGSNSGNTATLTISGTQAMDEADYYCQAWDSSTVFGGGTKLTVL | 170 | 187 | 239 | 247 | 356 | 379 |
EVQLVQSGAEAKKPGESLRISCKTSGYSFSSYWIGWVRQMPGKGLEWMGNFYPGDSDTRYSPSFQGQVTISADWSITTAYLQWSSLKASDTAIYYCARGLYYSFLTGHYNGNVAFDIWGQGTMVTVSS | 192 | 215 | 267 | 290 | 405 | 467 | DIVMTQSPDSLAVSLGERATINCRSSQSVLYSSNSKNYLAWYQQKPGQPPKLLIYWASTRESGVPERFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSNPYTFGQGTKVEIK | 169 | 204 | 256 | 264 | 373 | 399 |
DVQLVESGGGLVKPGGSLRLSCVASGFTFSRQSMHWVRQAPGKGLEWVSSITSRSDFIYYRDSVKGRFTISRDNARNSLFLQMTSLRAEDTAVYYCARDETTLGGDWGRGTLVTVSS | 212 | 235 | 287 | 310 | 425 | 454 | QSVLTQPPSASGTPGQRVTISCSGSSSNIGSRTVNWYQQLPGTAPRLFIYNNNQRPSGVPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDVSLSGWVFGGGTKLTVL | 180 | 203 | 255 | 263 | 372 | 404 |
QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYYMHWVRQAPGQGLEWMGIINPSGGSTSYAQKFQGRVTMTRDTSTSTVYMELSSLRSEDTAVYYCARGATMVRGRIDPWGQGTLVTVSS | 191 | 214 | 266 | 289 | 404 | 442 | QSALTQPPSASGSPGQSVTISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYEVSKRPSGVPDRFSGSKSGNTASLTVSGLQAEDEADYYCSSYAGSNNLVFGGGTKLTVL | 174 | 200 | 252 | 260 | 369 | 398 |
QVQLQESGPGLVKPSETLSLTCSVSGYSITSGHYWGWIRQSPEKGLEWIGSIYKSGTTYYNPTLNSRVTMSVDTSKNQFSLNLSSVSASDTAVYYCARGRQWLMYYFDYWGQGALVTVSS | 174 | 200 | 252 | 272 | 387 | 425 | EIVLTQSPGTLSLSPGESATLSCRASQSVSTTYLAWYQQRPGQAPRLLIYGGSGRATDIPDRFTGSGSGTDFTLTISRLEPEDFGVYYCQQYGSSVTFGGGTKVEIK | 191 | 211 | 263 | 271 | 380 | 403 |
QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYAISWVRQAPGQGLEWMGGIIPIFGTANYAQKFQGRVTITADESTSTAYMELSSLRSEDTAVYYCARDQGFELWLLYYWGQGTLVTVSS | 191 | 214 | 266 | 289 | 404 | 442 | DIVMTQSPDSLAVSLGERATINCKSSQSVLYSSNNKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSTPRTFGQGTKLEIK | 169 | 204 | 256 | 264 | 373 | 399 |
EVQLLESGGGLVQPGGSLRLSCAASGFTFRNYAMSWVRQAPGKGLEWVSAVRGSGNDPYYADSVKGRFTISRDNSRNTLYLQMNSLRAEDTAVYYCAKILTTVTTFEYFQDWGQGTLVTASS | 212 | 235 | 287 | 310 | 425 | 469 | DIQMTQSPSSVSASVGDRVTITCRATEDINNWLAWYQQEPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISGLQPEDFATYYCQQAKSFPLTFGGGTKVEIK | 172 | 189 | 241 | 249 | 358 | 384 |
EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYSMNWVRQAPGKGLEWVSSISSSSSYIYYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARGAYMVRGVSHHYYYYMDVWGKGTTVTVSS | 212 | 235 | 287 | 310 | 425 | 484 | EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSPWTFGQGTKVEIK | 183 | 203 | 255 | 263 | 372 | 398 |
EVQLVESGGGLVPPGGSLTLSCAASGFTLSNYWLYWVRQSPGKGLEWVAYFKGDGSSTKFADSVKGRFTFSRGNARNILYLQMNNLRAEDTAMYYCARDGPAIMVDFDFWGRGTLVTVSS | 203 | 226 | 278 | 301 | 416 | 454 | DIVMTQAPLSLPVTPGEPASISCRSSQSLLHSSGYNFLDWYLQKPGQSPQLLIYLGSSRASGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCMQALQAPITFGQGTRLEIK | 174 | 206 | 258 | 266 | 375 | 401 |
QVQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAPGQGLEWMGRINPNSGGTNYAQKFQGRVTMTRDTSISTAYMELSRLRSDDTAVYYCAVGRIYDSSGYYALAGYFDYWGQGTLVTVSS | 197 | 220 | 272 | 295 | 410 | 469 | EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSPLTFGGGTKVEIK | 183 | 203 | 255 | 263 | 372 | 398 |
QITLKESGPTLVKPTQTLTLTCTFSGFSLSTSGVGVGWIRQPPGKALEWLALIYWNDDKRYSPSLKSRLTITKDTSKNQVVLTMTNMDPVDTATYYCAHSAGEILDFDYWGQGTLVTVSS | 157 | 186 | 238 | 258 | 373 | 408 | QSALTQPPSASGSPGQSVTISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYEVSKRPSGVPDRFSGSKSGNTASLTVSGLQAEDEADYYCSSYAGSNLRVFGGGTKLTVL | 174 | 200 | 252 | 260 | 369 | 398 |
QVQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAPGQGLEWMGWINPNSGGTNYAQKFQGRVTMTRDTSISTAYMELSRLRSDDTAVYYCARAPRFGFWSGYSYGMDVWGQGTTVTVSS | 197 | 220 | 272 | 295 | 410 | 463 | QSALTQPASVSGSPGQSITISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYEVSNRPSGVSNRFSGSKSGNTASLTISGLQAEDEADYYCSSYTSSSTYVFGTGTKVTVL | 174 | 200 | 252 | 260 | 369 | 398 |
QVQLQESGPGLVKPSQTLSLTCSVSGGSIRSGGYHWNWIRQCPGKGLEWIGYIDDRGNTEYDASLRSRGVISVDRSLKQFSLRLTSVTAADTAVYYCARDKDETGIGSFDQWGRGTLVTVSS | 193 | 222 | 274 | 294 | 409 | 450 | DIVMTQSPDSLAVSLGERATISCKSSQSILNRSNNKNYLAWYQQKPGQPPKLLVYWASTRESGVPDRFSGSGSGTDFTLSISSLQAEDVAVYYCQHYFSRPFTFGQGTKLEIK | 169 | 204 | 256 | 264 | 373 | 399 |
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Paired SARS-COV-2 heavy/light chain sequences from the Observed Antibody Space database
Human paired heavy/light chain amino acid sequences from the Observed Antibody Space (OAS) database obtained from SARS-COV-2 studies.
https://opig.stats.ox.ac.uk/webapps/oas/
Please include the following citation in your work:
Olsen, TH, Boyles, F, Deane, CM. Observed Antibody Space: A diverse database of cleaned, annotated, and translated unpaired and paired antibody sequences. Protein Science. 2022; 31: 141–146. https://doi.org/10.1002/pro.4205
Data Preparation
This data was obtained on August 3, 2023 by searching the OAS Paired Sequence database with the following criteria:
- Species = "human"
- Disease = "SARS-COV-2"
This returned 704,652 filtered sequences from 3 studies split across 63 .csv.gz data unit files. These were extracted and filtered for records where both the complete_vdj_heavy
and complete_vdj_light
values were "T". Finally, the sequence_alignment_aa_heavy
and sequence_alignment_aa_light
fields were extracted into dataset and a 90/10 train/test applied. The resulting data was saved in pyarrow format.
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