sequence_alignment_aa_heavy
stringlengths
110
157
cdr1_start_heavy
int64
133
563
cdr1_end_heavy
int64
156
586
cdr2_start_heavy
float64
208
638
cdr2_end_heavy
float64
231
667
cdr3_start_heavy
float64
346
782
cdr3_end_heavy
float64
372
835
sequence_alignment_aa_light
stringlengths
100
126
cdr1_start_light
int64
133
822
cdr1_end_light
int64
152
848
cdr2_start_light
float64
204
900
cdr2_end_light
float64
212
908
cdr3_start_light
float64
321
1.02k
cdr3_end_light
float64
350
1.05k
QVQLQESGPGLVKPSGTLSLTCTVSGHSISRSHWWSWVRQAPGKGLEWIGEIYHSGTTNYNPSLKSRVTISVDKSNNQFSLTLNSMTAADTALYYCARGREGNWNYILDSWGRGTLVTVSS
168
194
246
266
381
422
EVVLTQSPATLSLSPGERATLSCRASQSIGNYLAWYQQKPGQAPRLLIYDASNRATAVPARFSGGGSGTDFTLSISSLEPEDFAIYYCLHRSNWLTFGGGTKVEIK
175
192
244
252
361
384
QVQLVESGGGVVQPGRSLTLSCAASGFTFSSYGLHWVRQAPGKGLEWVANIWYDGANKYYGDSVKGRFTISRDNSRNTLYLQMNSLTAEDTAVYYCARWIEYGSGKDAFDVWGQGTMVIVSS
213
236
288
311
426
470
DIQLTQSPSSLSASVGDRVTITCRASQYINNLLNWYQQKPGKAPKVLIYGASNLQSGVPSRFSGSGSGTDFTLTISGLQLEDFATYFCQQSYSTWTFGQGTKVEIK
175
192
244
252
361
384
QVQLQESGPGLVKPSETLSLTCTVSGGSISSYYWSWIRQPPGKGLEWIGYIYYSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARDANSHGLGYWGQGTLVTVSS
192
215
267
287
402
434
DIQMTQSPSSLSASVGDRVTITCRASQGISNYLAWFQQKPGKAPKSLIYAASSLQSGVPSKFSGSGSGTDFTLTISSLQPEDFATYYCQQYNSYPWTFGQGTKVEIK
172
189
241
249
358
384
QVTLRESGPALVKPTQTLTLTCTFSGFSLSTSGMCVSWIRQPPGKALEWLALIDWDDDKYYSTSLKTRLTISKDTSKNQVVLTMTNMDPVDTATYYCARQYYYDSSGYYYDWYFDLWGRGTLVTVSS
152
181
233
253
368
424
QSALTQPRSVSGSPGQSVTISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYDVSKRPSGVPDRFSGSKSGNTASLTISGLQAEDEADYYCCSYAGSYSVVFGGGTKLTVL
175
201
253
261
370
399
QLQLQESGPGLVKPSETLSLTCTVSGGSISSSSYYWGWIRQPPGKGLEWIGSIYYSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARELLWELEEADWFDPWGQGTLVTVSS
190
219
271
291
406
453
DIQMTQSPSTLSASVGDRVTITCRASQSISSWLAWYQQKPGKAPKLLIYKASSLESGVPSRFSGSGSGTEFTLTISSLQPDDFATYYCQQYNSYWRTFGQGTKVEIK
171
188
240
248
357
383
EVQLVESGGGVVQPGGSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSLISGDGGSTYYADSVKGRFTISRDNSKNSLYLQMNSLRTEDTALYYCAKDYYDSSGPDYWGQGTLVTVSS
213
236
288
311
426
461
DVVMTQSPLSLPVTLGQPASISCRSSQSLVYSDGNTYLNWFQQRPGQSPRRLIYKVSNRDSGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCMQGTHWPHTFGQGTKLEIK
192
224
276
284
393
419
QVQLQESGPGLVKPSETLSLTCTVSGGSFRSYYWSWIRQPPGKGLEWIGYIYYSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCASTSAGYWGQGTLVTVSS
207
230
282
302
417
437
DIQMTQSPSSLSASVGDSVTITCRASQSIRNYLSWYHHKPGQAPKLLIYGASSLQSGVPSRFSGSGSGTDFTLTISSLQAEDFATYYCQQSDSLPWTFGQGTKVDIK
179
196
248
256
365
391
DVQLLESGGGLVQPGGSLRLSCAASGFTFSNYALSWVRQAPGKGLEWVSSIIGSGGVTSYADSVRGRFTISRDNSKNTLYLQMDSLRTEDTAVYYCARDGGTPQYNLNYFYWGQGTLVTVSS
212
235
287
310
425
469
EIVLTQSPDTLSLSPGERATLSCRASQTITNNYLAWYRQKPGQAPRLLIYAASYRAAGIPDRFSGGGSGTDFTLTISRLEPEDFAMFYCHQYGTSPTFGQGTKVEIK
175
195
247
255
364
387
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSKTDGGTTDYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTAVYYCTTDPLYYDFWSGPTLGDYWGQGTLVTVSS
213
236
288
317
432
485
EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWPPYTFGQGTKLEIK
186
203
255
263
372
401
DVQLVESGGGLAQPGGSLRLSCAASGFTFSSYWMTWVRRAPGKGLEWVANINGNGKEYVESVKGRFTISRDNAKNSLFLQMNSLRVEDTAVYYCARDPYDHDSGSYGAFDVWGQGTPVTVSS
212
235
287
304
419
469
DVVMTQSPLSLPVTLGQPASISCRSSQSLVYKDGNTYLNWFQQRPGQSPRRLIYKVSNRDSGVPDRFSGSGSGTDFTLKISRVEAEDVGIYYCMQGTQWPYTFGQGTKLEIK
200
232
284
292
401
427
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSKTDGGTTDYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTAVYYCTTAEGSFDYWGQGTLVTVSS
213
236
288
317
432
458
SYELTQPPSVSVSPGQTASITCSGDKLGDKYACWYQQKPGQSPVLVIYQDSKRPSGIPERFSGSNSGNTATLTISGTQAMDEADYYCQAWDSSGVFGGGTKLTVL
294
311
363
371
480
503
QVQLQESGPGLVKPSQTLSLTCTVSGGSISSGSYYWSWIRQPAGKGLEWIGRIHISGSTNYNPSLKSRVTMSVDTSRNQFSLKLSSVTAADTAVYYCAASTGGYSSSWAEYYFGYWGQGTLVTVSS
168
197
249
269
384
437
DIVMTQSPDSLAVSLGERATINCKSSQNVLYSSNNKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSTPYTFGQGTKLEIK
169
204
256
264
373
399
QITLKESGPTLVKPTQTLTLTCTFSGFSLSTSGVGVGWIRQPPGKALEWLALIYWDDDKRYSPSLKSRLTITKDTSKNQVVLTMTNMDPVDTATYYCAHQSPYYGSVAFDYWGQGTLVTVSS
157
186
238
258
373
414
QSVLTQPPSVSAAPGQKVTISCSGSSSNIGNNYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSLSAYVFGTGTKVTVL
169
192
244
252
361
393
EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKFFAPVAYYYDSSEQGDYYGMDVWGQGTTVTVSS
212
235
287
310
425
496
AIRMTQSPSSFSASTGDRVTITCRASQGISSYLAWYQQKPGKAPKLLIYAASTLQSGVPSRFSGSGSGTDFTLTISCLQSEDFATYYCQQYYSYPLTFGGGTKVEIK
172
189
241
249
358
384
EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKDVWYYDSSGYNDYWGQGTLVTVSS
212
235
287
310
425
469
EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWPWGAFGPGTKVDIK
186
203
255
263
372
401
QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYYMHWVRQAPGQGLEWMGRINPNSGSTNYAQKFQGRVTMTSDTSTSTVYMELSSLRSEDTAVYYCARPALAYSINWSSLDWFDPWGQGTLVTVSS
191
214
266
289
404
460
DIQMTQSPATLSAFVGDRVTITCRASQSISSWLAWYQQKPGKAPKLLIQKASSLESGVPSRFSGSGSGTEFTLTISRLQPDDFATYYCQQYNTYSLTFGGGTKVEIK
172
189
241
249
358
384
EVQLVESGGGFVHPGESLRLSCVASGFTFRPFWMNWVRQVPGKGLEWVATIGEDESRTWYLDSVKGRFTISRDNTKNSLYLQMDNLKAEDSAIYYCTRDPDTSSKVDFWGQGTLVTVSS
212
235
287
310
425
460
DVVMTQSPLSLPVTLGQPASISCRSSLSLVYSDGNAYLSWFQQRPGQSPRRLIYEVSKRDSGVPDRFSGSGSGTDFTLRISRVEAEDVGYYYCMQGTYRPPTFGQGTRLEIK
169
201
253
261
370
396
DVKLLESGGSVVQPGGSLRLSCAASGFSFSSYAMSWVRQAPGRGLEWVSTITNSGTNTYFTDSVKGRFAISRDNSRETLYLQLNSLRAEDTAVYYCAKTWWGGTNENSVWFDPWGQGTLVTVSS
212
235
287
310
425
475
EIVLTQSPATLSLSPGERATLSCRASQSVSSFLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSSWPPITFGQGTRLEIK
186
203
255
263
372
401
EVQLVESGGGLVQPGGSLRLSCAASGFTFSGYSMNWVRQAPGKGLEWVSYISSGGSPIHYADSVKGRFTISRDNANNSLYLQMNSLRDEDTAVYYCARDYDSSGRAFDYWGQGTLVTVSS
212
235
287
310
425
463
QSVLTQPPSVSAAPGQKVTISCSGSRSNMGIHYVSWYQQLPGTAPQLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSLSGVVFGGGTKLTVL
169
192
244
252
361
393
EVQLVESGGGVVQPGGSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSLISGDGGSTYYADSVKGRFTISRDNSKNSLYLQMNSLRTEDTALYYCATGGSYGYYYGMDVWGQGTTVTVSS
213
236
288
311
426
467
EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSLWTFGQGTKVEIK
223
243
295
303
412
438
EVQLVQSGAEVKKPGESLKISCKGSGYIFTNYWIGWVRQMPGKGLEWMGIIYPGDSDTRYSPSFQGQVTMSADKSVSTAYLQWSSLKASDTAMYYCARHGGHCNGGSCSRLPPGSYAMDGWGQGTTVTVSS
192
215
267
290
405
476
DIVMTQSPLSLPVTPGEPASISCRSSQSLLHSNGYNYLDWYLQKPGQAPQLLIYLGSNRASGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCMQALQTPYAFGQGTKLEIK
174
206
258
266
375
401
EVQLVESGGGLVQPGRSLRLSCTASGFTFGDYAMSWVRQAPGKGLEWVGFIRSKAYGGTTEYAASVKGRFTISRDDSKSIAYLQMNSLKTEDTAVYYCTRDHPEWELRVSFDYWGQGTLVTVSS
213
236
288
317
432
476
DIQMTQSPSSLSASVGDRVTITCQASQDISNYLNWYQQKPGKAPKLLIYDASNLETGVPSRFSGSGSGTDFTFTISSLQPEDIATYYCQQYDNLPQTFGGGTKVEIK
176
193
245
253
362
388
EVQLVESGGGLVQPGGSLKLSCAASGFTFSGSAMHWVRQASGKGLEWVGRIRSKANSYATAYAASVKGRFTISRDDSKNTAYLQMNSLKTEDTAVYYCTRGLIYDSSGSPFDYWGQGTLVTVSS
213
236
288
317
432
476
QTVVTQEPSLTVSPGGTVTLTCASSTGAVTSGYYPNWFQQKPGQAPRALIYSTSNKHSWTPARFSGSLLGGKAALTLSGVQPEDEAEYYCLLYYGGAVVFGGGTKLTVL
167
193
245
253
362
388
QITLKESGPTLVKPTQTLTLTCTFSGFSLSTSGVGVGWIRQPPGKALEWLALIYWNDDKRYSPSLKSRLTITKDTSKNQVVLTMTNMDPVDTATYYCAHRPLLWFGEASGRWFDPWGQGTLVTVSS
157
186
238
258
373
426
DIQMTQSPSSVSASVGDRVTITCRASQGISSWLAWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQANSFPFTFGPGTKVDIK
172
189
241
249
358
384
QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYAINWVRQAPGQGLEWMGGIIPVFDTTNYAQKFQGRVTITADKSTTTAYMELSSLRSEDAAMYYCARAADRGTYYNYYGMDVWGQGTTVTVSS
181
204
256
279
394
444
EIVLTQSPGSLSLSPGERATLSCRASQSVSRNYLAWYQQKPGQAPRLLIYGASSRATGISDRFSGSGSGTDFTLTINRLEPEDFAVYHCQQYGGLPWTFGQGTKLEIK
183
203
255
263
372
398
QVQLQESGPGLVKPSQTLSLTCTVSGGSISSGSYYWSWIRQPAGKGLEWIGRIYTSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARGGELSLIYYYYGMDVWGQGTTVTVSS
168
197
249
269
384
434
SSELTQDPAVSVALGQTVRITCQGDSLRSYYASWYQQKPGQAPVLVIYGKNNRPSGIPDRFSGSSSGNTASLTITGAQAEDEADYYCNSRDSSGNHLEVFGTGTKVTVL
173
190
242
250
359
394
QVQLQESGPGLVKPSETLSLTCTVSGGSVSSSNYYWTWLRQSPGKGLEWIGYVYYTGTTNYNPSLETRVIISVDTSKNQFSLRLNSVTAADTAVYYCARDEGLSGPRDGGFDPWGQGTLVTVSS
170
199
251
271
386
433
EIVMTQTPLSSPVTLGQPASISCRSSQSLLHSDGNTYLSWLQQRPGQPPRLLIYKISNRFSGVPDRFSGSGAGTDFTLKISRVEAEDVGVYYCMQARQFPYTFGQGTKLEIK
169
201
253
261
370
396
QVQLVESGGGLVKPGGSLRLSCAASGFTFSDYYMSWIRQAPGKGLEWVSYISSSGSTIYYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARDPQWLARFDYWGQGTLVTVSS
213
236
288
311
426
461
QSVLTQPPSASGTPGQRVTISCSGSSSNIGSNTVNWYQQLPGTAPKLLIYSNNQRPSGVPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDDSLNGRVVFGGGTKLTVL
180
203
255
263
372
407
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSKTDGGTTDYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTAVYYCTTDPSKNCGGDCYSYYYYYYMDVWGKGTTVTVSS
213
236
288
317
432
500
DIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTPKTFGQGTKVEIK
172
189
241
249
358
384
QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYGISWVRQAPGQGLEWMGWISAYNGNTNYAQKLQGRVTMTTDTSTSTAYMELRSLRSDDTAVYYCARTRLAAYYYYGMDVWGQGTTVTVSS
187
210
262
285
400
444
DIVMTQSPLSLPVTPGEPASISCRSSQSLLHSNGYNYLDWYLQKPGQSPQLLIYLGSNRASGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCMQALQTLWTFGQGTKVEIK
174
206
258
266
375
401
QVQLQESGPGLVKPSGTLSLTCAVSGGSISSNNWWNWVRQPPGKGLEWIGEIYHTGRTNYNPSLKSRVTISVDKSKNQFSLRLSSVTAADTAVYYCARGGGPYFDYWGQGTLVTVSS
172
198
250
270
385
414
EIVLTQSPGTLSLSPGERATLSCRASQSVISDYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSIMYTFGQGTKLEIK
175
195
247
255
364
393
EVQLAESGGGLVQPGGSLRLSCAASGFTFSNYWMNWVRQAPGKGLEWVANIKQDGNTIYYVDSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCAKGGLAPGDYWGQGTLVTVSS
212
235
287
310
425
454
QSVLTQPPSASGTPGQRVTISCSGSNSNIGNNPVNWYQHLPGTAPKLLIYTNNERPSGVPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDGSLSGYIFGTGTKVTVL
180
203
255
263
372
404
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSRTDGGTTDYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTGVYYCTTHYYDRSGYYPGYFHHWGQGTLVTVSS
213
236
288
317
432
482
DIVMTQSPDSLAVSLGERATINCKSGHSVLYSSNSKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSPPLTFGGGTKVEIK
169
204
256
264
373
399
QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYTISWVRQAPGQGLEWMGRIIPILGIANYAQKFQGRVTITADKSTSTAYMELSSLRSEDTAVYYCASDPQSHYDSSGYYHWGQGTLVTVSS
184
207
259
282
397
441
DIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTRITFGQGTRLEIK
174
191
243
251
360
386
QITLKESGPTLVKPTQTLTLTCTFSGFSLSTSGVGVGWIRQPPGKALEWLALIYWNDDKRYSPSLKSRLTITKDTSKNQVVLTMTNMDPVDTATYYCAHFNYYDSSGYWTPGRGYFDYWGQGTLVTVSS
153
182
234
254
369
431
QSALTQPRSVSGSPGQSVTISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYDVSKRPSGVPDRFSGSKSGNTASLTISGLQAEDEADYYCCSYAGSYSVVFGGGTKLTVL
175
201
253
261
370
399
EVRLAESGCSLVQPGGSLSLSCAASGFSLSGYWMHWVRRVPGKGLVWVARISSDGSSTEYADAVKGRFTISRDNAKNTLFLQMNSLRAEDTAVYHCTRGGSVDVIRGVFDSWGQGALVTVSS
201
224
276
299
414
458
DIVMTQSPDSMAVSLGERATINCKSSQSVLYSPNNKNDLTWYQHKPGQPPRLLIYWASTRASGVPDRFSGSGSGTDFTLTISNLQAEDGAIYYCQQHKSDPYTFGQGTKLEIK
169
204
256
264
373
399
EVQLAEAGGGLVQPGGSRRLSCAASGFTFGSYWVSWVRQAPGKGLEWVANINQDGSQKHFVDSVKGRFTISRDSAKNSVYLQIDSLRAEDTALYYCAVDSSGSYGWDSWGQGTLVTVSS
212
235
287
310
425
460
DIQMTQSPSSLSASVGDRVTITCRASQSITRYLNWYQQKPGKAPKLLIYGTSSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSDSVPRTFGQGTKVEIK
175
192
244
252
361
387
EVQLVESGGGLVQPGGSLRLSCAASGFTFSTYWMSWVRQAPGKGLEWVANIKQDESEKYYVDSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARSTYCTSTSCYHYYYYGMDVWGQGTTVTVSS
212
235
287
310
425
487
DIQMTQSPSTLSASVGDRVTITCRASQSISSWLAWYQQKPGKAPNLLIYKASSLESGVPSRFSGSGSGTEFTLTISSLQPDDFATYYCQQYNSYPWTFGQGTKVEIK
172
189
241
249
358
384
QLQLQESGPGLVKPSETLSLTCTVSGGSISSSSYYWGWIRQPPGKGLEWIGSIYYSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARLPSPYDSSGYPDAFDIWGQGTMVTVSS
204
233
285
305
420
473
EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWPLTFGGGTKVEIK
186
203
255
263
372
398
EVQLVESGGGVVQPGGSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSLISGDGGSTYYADSVKGRFTISRDNSKNSLYLQMNSLRTEDTALYYCAKDDYWGQGTLVTVSS
213
236
288
311
426
440
EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWPPVTFGPGTKVDIK
186
203
255
263
372
401
QVQLVQSGSELKKPGASVKVSCKASGYTFTSYAMNWVRQAPGQGLEWMGWINTNTGNPTYAQGFTGRFVFSLDTSVSTAYLQISSLKAEDTAVYYCARADMIDYGVSLNWFDPWGQGTLVTVSS
182
205
257
280
395
445
SYVLTQPPSVSVAPGKTARITCGGNNIGSKSVHWYQQKPGQAPVLVIYYDSDRPSGIPERFSGSNSGNTATLTISRVEAGDEADYYCQVWDSSSDHYVVFGGGTKLTVL
173
190
242
250
359
394
QVQLQESGPGLVKPSETLSLTCTVSGGSISSYYWSWIRQPPGKGLEWIGYIYYSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARFMPQNFYYYYGMDVWGQGTTVTVSS
168
191
243
263
378
425
QTVVTQEPSLTVSPGGTVTLTCASSTGAVTSGYYPNWFQQKPGQAPRALIYSTSNKHSWTPARFSGSLLGGKAALTLSGVQPEDEAEYYCLLYYGGVWVFGGGTKLTVL
167
193
245
253
362
388
QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYYMHWVRQAPGQGLEWMGIINPSGGSTSYAQKFQGRVTMTRDTSTSTVYMELSSLRSEDTAVYYCASPGGFGELLYPRGYYGMDVWGQGTTVTVSS
191
214
266
289
404
463
DIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTPYTFGQGTKLEIK
175
192
244
252
361
387
QLQLQESGPGLVKPSETLSLTCTVSGGSISSSSYYWGWIRQPPGKGLEWIGSIYYSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCASWYYDILTGYYNWGQGTLVTVSS
175
204
256
276
391
429
QSALTQPASVSGSPGQSITISCTGTSSDVGSYNLVSWYQQHPGKAPKLMIYEGSKRPSGVSNRFSGSKSGNTASLTISGLQAEDEADYYCCSYAGSSVVFGGGTKLTVL
171
197
249
257
366
392
QVQLVESGGGLVKPGGSLRLSCAASGFTFSDYYMSWIRQAPGKGLEWVSYISSSGSTIYYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARSYYDMHYYYYGMDVWGQGTTVTVSS
213
236
288
311
426
473
DIQMTQSPSTLSASVGDRVTITCRASQSISSWLAWYQQKPGKAPKLLIYKASSLESGVPSRFSGSGSGTEFTLTISSLQPDDFATYYCQQYNSYPYTFGQGTKLEIK
172
189
241
249
358
384
EVQLVESGGGLVQPGRSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSGISWNSGSIGYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTALYYCAKRLGLCSSTSCYSFQGDAFDIWGQGTMVTVSS
218
241
293
316
431
496
QSVLTQPPSASGTPGQRVTISCSGSSSNIGSNTVNWYQQLPGTAPKLLIYSNNQRPSGVPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDDSLNGWVFGGGTKLTVL
180
203
255
263
372
404
QITLKESGPTLVKPTQTLTLTCTFSGFSLSTSGVGVGWIRQPPGKALEWLALIYWDDDKRYSPSLKSRLTITKDTSKNQVVLTMTNMDPVDTATYYCAHAPMVRGVMGAFDIWGQGTMVTVSS
158
187
239
259
374
418
QSVLTQPPSASGTPGQRVTISCSGSSSNIGSNTVNWYQQLPGTAPKLLIYSNNQRPSGVPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDDSLNGPVFGGGTKLTVL
198
221
273
281
390
422
EVQLVESGGGLVQPGRSLRLSCTASGFTFGDYAMSWVRQAPGKGLEWVGFIRSKAYGGTTEYAASVKGRFTISRDDSKSIAYLQMNSLKTEDTAVYYCTREGGATGDAFDIWGQGTMVTVSS
213
236
288
317
432
470
QSVLTQPPSVSGAPGQRVTISCTGSSSNIGAGYDVHWYQQLPGTAPKLLIYGNSNRPSGVPDRFSGSKSGTSASLAITGLQAEDEADYYCQSYDSSLSGHVVFGGGTKLTVL
184
210
262
270
379
414
EVHLVESGGGLVQPGGSLRLSCAASGFIFSSYGMHWVRQAPGKGLVWVSRINSDGSITNYADSVKGRFTISRDNAKNTLSLQMNSLRAEDTAVYFCTRSNKGHCSGVGCYLGPEYWGQGTLVTVSS
242
265
317
340
455
511
QSVLTQPPSASGTPGRRVTISCSGSSSNVGSNTVNWYQHLPGMAPKLLIYSNNQRPSGVPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDDSLNGWVFGGGTKLTVL
180
203
255
263
372
404
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGHIKSKTDGGTTDYAAPVKGRFTISRDGSKNTLYLQMNSLKTEDTAIYYCTTDTSWGPYYFDYWGQGTLVTVSS
213
236
288
317
432
470
QSALTQPASVSGSPGQSITFSCTGTSSDVGSYNPVSWYQQHPGKAPKLMIYEDSKRPSGVSNRFSGSKSGNTASLTISGLQAEDEADYYCCSYAGTSTWVFGGGTKLTVL
171
197
249
257
366
395
QLQLQESGSGLVKPSQTLSLTCAVSGGSISSGGYSWSWIRQPPGKGLEWIGYIYHSGSTYYNPSLKSRVTISVDRSKNQFSLKLSSVTAADTAVYYCARVVSLVKAFDIWGQGTMVTVSS
168
197
249
269
384
419
QSALTQPASVSGSPGQSITISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYEVSNRPSGVSNRFSGSKSGNTASLTISGLQAEDEADYYCSSYTSSSTDVFGTGTKVTVL
174
200
252
260
369
398
EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKGTYCSGGSCYSPKRTVEKDYYYYGMDVWGQGTTVTVSS
212
235
287
310
425
511
DIVMTQSPLSLPVTPGEPASISCRSSQSLLHSNGYNYLDWYLQKPGQSPQLLIYLGSNRASGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCMQALQTPWTFGQGTKVEIK
175
207
259
267
376
402
EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKNIPLPGIAVAGSFDYWGQGTLVTVSS
212
235
287
310
425
475
EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWPPLTFGGGTKVEIK
186
203
255
263
372
401
EVQLVESGGGLVQPGGSLRLSCVASGFSTSNYWMGWVRQAPGKGLEWVANIKQDGSEKYYGDSVKGRFTISRDNAKNSLYLQINSLRAEDTAVYYCARAHSGGIGARLYWGQGTLVTVSS
212
235
287
310
425
463
EIVMTQSPATLSVSPGERATLSCRASQSVSSNLAWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTEFTLTISSLQSEDFAVYYCHQYDNWPWTSGQGTKVEIK
175
192
244
252
361
387
EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAATLVPAATQSPDYWGQGTLVTVSS
212
235
287
310
425
466
AIRMTQSPSSFSASTGDRVTITCRASQGISSYLAWYQQKPGKAPKLLIYAASTLQSGVPSRFSGSGSGTDFTLTISCLQSEDFATYYCQQYYSYPPTFGQGTKLEIK
172
189
241
249
358
384
QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYAMHWVRQAPGKGLEWVAVISYDGSNKYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARVGSSGWYNGDYYYYGMDVWGQGTTVTVSS
200
223
275
298
413
472
DIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTPLTFGGGTKVEIK
180
197
249
257
366
392
EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKDRFLHAGIAAAVDYWGQGTLVTVSS
206
229
281
304
419
466
DIQMTQSPSSLSASVGDRVTITCQASQDISNYLNWYQQKPGKAPKLLIYDASNLETGVPSRFSGSGSGTDFTFTISSLQPEDIATYYCQQYDNSLTFGGGTKVEIK
176
193
245
253
362
385
QVQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAPGQGLEWMGWINPNSGGTNYAQKFQGRVTMTRDTSISTAYMELSRLRSDDTAVYYCARGLLAAAGNYYYYGMDVWGQGTTVTVSS
195
218
270
293
408
461
SYVLTQPPSVSVAPGQTARITCGGNNIGSKSVHWYQQKPGQAPVLVVYDDSDRPSGIPERFSGSNSGNTATLTISRVEAGDEADYYCQVWDSSSDLGGVFGGGTKLTVL
258
275
327
335
444
479
QVQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAPGQGLEWMGWINPNSGGTNYAQKFQGWVTMTRDTSISTAYMELSRLRSDDTAVYYCARARNHLKYSSSSSHYYYYGMDVWGQGTTVTVSS
197
220
272
295
410
478
QTVVTQEPSFSVSPGGTVTLTCGLSSGSVSTSYYPSWYQQTPGQAPRTLIYSTNTRSSGVPDRFSGSILGNKAALTITGAQADDESDYYCVLYMGSGIWVFGGGTKLTVL
178
204
256
264
373
402
EVQLVESGGGLVQPGRSLRLSCTASGFTFGDYAMSWVRQAPGKGLEWVGFIRSKAYGGTTEYAASVKGRFTISRDDSKSIAYLQMNSLKTEDTAVYYCTRGPYGDSTYYYYGMDVWGQGTTVTVSS
213
236
288
317
432
482
QPVLTQPPSASASLGASVTLTCTLSSGYSNYKVDWYQQRPGKGPRFVMRVGTGGIVGSKGDGIPDRFSVLGSGLNRYLTIKNIQEEDESDYHCGADHGSGSNFVFVFGGGTKLTVL
170
190
242
265
374
412
QVQLQESGPGLVKPSQTLSLTCTVSGGSISSGSYYWSWIRQPAGKGLEWIGRIYTSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARAPRARSSRVDYFDYWGQGTLVTVSS
179
208
260
280
395
442
VIWMTQSPSLLSASTGDRVTISCRMSQGISSYLAWYQQKPGKAPELLIYAASTLQSGVPSRFSGSGSGTDFTLTISCLQSEDFATYYCQQYYSFPYTFGQGTKLEIK
172
189
241
249
358
384
QVQLVQSGAEVKKPGASVKVSCKASNYPFTTYGISWVRQAPGQGLEWMGWINAYNGNTNFAQKLQDRVTMTTDTSTSTAYMELRSLRSDDTAVYYCARDGSGTWNDYWGQGTLVAVSS
192
215
267
290
405
437
QLVLTQSPSASASLGASVKLTCILSSGHSSYAIAWHQQQPEKGPRYLMKVNRDGSHSKGDGIPDRFSGSSSGAERYLTISSLQSEDEADYYCQTWGTGIQVFGGGTKLTVL
158
178
230
250
359
385
QVQLQESGPGLVKPSETLSLTCTVSGGSISSYYWSWIRQPPGKGLEWIGYIYYSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARAGPAYCSGGSCYSEPYHYYYYGMDVWGQGTTVTVSS
170
193
245
265
380
460
SYELTQPPSVSVSPGQTASITCSGDKLGDKYACWYQQKPGQSPVLVIYQDSKRPSGIPERFSGSNSGNTATLTISGTQAMDEADYYCQAWDSSTAVVFGGGTKLTVL
219
236
288
296
405
434
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSKTDGGTTDYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTAVYYCTTVTRGYRSNWFDPWGQGTLVTVSS
213
236
288
317
432
473
SYVLTQPPSVSVAPGQTARITCGGNNIGSKSVHWYQQKPGQAPVLVVYDDSDRPSGIPERFSGSNSGNTATLTISRVEAGDEADYYCQVWDSSSDHPVFGGGTKLTVL
267
284
336
344
453
485
EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYSMNWVRQAPGKGLEWVSSISSSSSYIYYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARLLYDEWEGYWGQGTLVTVSS
212
235
287
310
425
457
QLVLTQSPSASASLGASVKLTCTLSSGHSSYAIAWHQQQPEKGPRYLMKLNSDGSHSKGDGIPDRFSGSSSGAERYLTISSLQSEDEADYYCQTWGTGIVFGGGTKLTVL
158
178
230
250
359
382
QVQLQESGPGLVKPSQTLSLTCTVSGGSISSGGYYWSWIRQHPGKGLEWIGYIYYSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARGDYGDPPGYYGMDVWGQGTTVTVSS
192
221
273
293
408
455
AIRMTQSPSSFSASTGDRVTITCRASQGISSYLAWYQQKPGKAPKLLIYAASTLQSGVPSRFSGSGSGTDFTLTISCLQSEDFATYYCQQYYSYPWTFGQGTKVEIK
172
189
241
249
358
384
EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKVWGRLLWFGSPFDYWGQGTLVTVSS
212
235
287
310
425
472
EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSPWTFGQGTKVEIK
183
203
255
263
372
398
EVQLMESGGGVVQPGGSLRLSCAASGFTFSWFWMSWVRQAPGKGLEWVASIKPDGSEKYYVESVKGRLIISRDNANNEMYLQMNSLRAEDTAVYYCATEDKSAFESWGQGTLVTVSS
212
235
287
310
425
454
QSVLMQPPSVSAAPGQTVTISCSGSSSSIGNNFVSWYQLLPGAAPKLLIYENNKRPSGVPDRFSASKSGTSATLGITGLQTGDEADYYCGSWDRKVLGTGTKVTVL
169
192
244
252
361
381
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSKTDGGTTDYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTAVYYCTTDTLIAAAGARHLLYGMDYWGQGTLVTVSS
213
236
288
317
432
491
DIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTPLTFGGGTKVEIK
176
193
245
253
362
388
EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKDAAGTLWDTAMEGLGYYYYYYMDVWGKGTTVTVSS
212
235
287
310
425
502
EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGISDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSRGTFGQGTKVEIK
191
211
263
271
380
406
EVQLVDSGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGHIKSKTDGGTTDYAAPVKGRFTISRDDSKNTLFLQMNSLKTEDTAVYYCTTGDNWNYFYWGRGTLVTVSS
213
236
288
317
432
461
SYELTQPPSVSVSPGQTASITCSGDNLGNKYASWYQQKPGQSPVLVIYQDNKRPSGIPERFSGSNSGNTATLTISGTQAMDEADYYCQAWDSSTARFGGGTKLTVL
170
187
239
247
356
382
EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYSMNWVRQAPGKGLEWVSSISSSSSYIYYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARALYGDSVNYYYYGMDVWGQGTTVTVSS
212
235
287
310
425
478
QSVLTQPPSVSAAPGQKVTISCSGSSSNIGNNYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSLSAGVFGGGTKLTVL
169
192
244
252
361
393
QVQLQESGPGLVKPSETLSLTCTVSGGSITSDYWTWIRQPPGKGLEWIGYIYYSGNINYNPSLRSRVTISVDMSKNQFSLKLSSVTAADTAVYYCARYQYGAGPFDIWGQGTMVTVSS
170
193
245
265
380
415
DIQMTQSPPTLSASVGDRATITCRASQSISNRLAWYQQKPGKAPKLLIYKASTLESGVPSRFSGSGSGTEFTLTITSLQPDDFATYYCQQYDNYFRTFGQGTKVEIK
172
189
241
249
358
384
EVQLVESGGGLVQPGESLRLSCAASGFTFSDYSMAWVRQAPGKGLEWVANINQDGTKKNHLGSVTGRFAISRDNAKNSLYLQMNSLRAEDTAVYYCARDLGGRYDFWSHWGQGTLVAVSS
212
235
287
310
425
463
DIQMTQSPSSVSASIGDRVTITCRASHDIDGWLAWYQQKPGKAPKLLVYAASRLQSGVPSRFSGSGSGTDFALTISRLQPEDFATYYCHQANSFPLTFGGGTKVEIK
172
189
241
249
358
384
QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYAMHWVRQAPGKGLEWVAVISYDVGDKHYTDSVKGRFTISRDNSKNTLYLQMNSLRAEDTGVYYCARDTSAPFDSWGQGTLVTVSS
200
223
275
298
413
442
DIQMTQSPSSLSASVGDRVTITCRASQGINSYLAWFQQKPGKAPKSLIYAASTLQSGVPSKFSGSGSGTDFTLTISSLQPEDFATYYCQQYKSYPRTFGQGTKVEIK
172
189
241
249
358
384
QVQLQESGPGLVKPSETLSLTCTVSGGSISSYYWSWIRQPPGKGLEWIGYIYYSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARVCSSTSCYPKKDGWFDPWGQGTLVTVSS
170
193
245
265
380
436
EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSPSTFGQGTKLEIK
183
203
255
263
372
398
QLQLQESGPGLVKSSETLSLTCTVSGGSISSSSYYWGWIRQPPGKGLEWIGSIYYSGSSYHNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYFCASLTTVTTFGYWGQGTLVTVSS
174
203
255
275
390
422
QSVLTQPPSVSAAPGQKVTISCSGSSSNIGNNYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSVSAWVFGGGTKLTVL
169
192
244
252
361
393
EVQLVESGGGLVQPGRSLRLSCAASGFTFGNYAMYWVRQIPGKGLEWVSGISWNSDTIGYADSVKGRFTISRDNAKNSLYLQMNSLRVEDTAMYYCAKVGGLGSYYYTPIESWGQGTLVTVSS
228
251
303
326
441
488
DIQLTQSPSFLSASVGDRVTITCRASQGISSYLAWYQQKPGKAPKLLIYAASTLQSGVPSRFSGSGSGTEFTLTISSLQPEDFATYYCQQLNSYPRTFGQGTKVEIK
172
189
241
249
358
384
EVQLMESGGHLVQPGGSLKLSCAASGFTFSDYSMDWVRQAPGKGLEWVARMRDKAYTYTTQYAASVKGRFTISRDDSKSLVYLQMNSLKTEDTAVYYCSRDSYGNPDYWGQGTLVTVSS
213
236
288
317
432
461
DIQMTQSPSSLSASVGDRVTITCRASQDIRNDLGWYQQKPGKAPKRLIYATSTLQSGVPSRFSGSGSGTEFTLTITSLQPEDFATYYCLQYNTYPGTFGQGTKVEIK
181
198
250
258
367
393
QVQLQQSGPGLVKPSQTLSVTCAISGDSVSSNTATWNWIRQSPSRGLEWLGRTYFRSKWFYDYALSVKSRITINADTSRSQFSLQLNSVTPEDTAVYYCARERRFTFFGVVTRTNWYFDLWGRGTLVTVSS
188
217
269
295
410
472
SSELTQDPAVSVALGQTVRITCQGDSLRNYYASWYQQKPGQAPLLVIYGENYRPSGIPDRFSGSSSGNTASLTITGAQAEDEADYYCNSRDSSGNVVVFGGGTKLTVL
173
190
242
250
359
391
EVQLVESGGGLVQPGRSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSGISWNSGSIGYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTALYYCAKDESSGWYVFDYWGQGTLVTVSS
217
240
292
315
430
468
QSALTQPRSVSGSPGQSVTISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYDVSKRPSGVPDRFSGSKSGNTASLTISGLQAEDEADYYCCSYAGSYTWVFGGGTKLTVL
175
201
253
261
370
399
EVQLVESGGGLIKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRFMSKTDGGTTDYAAPVKGRFTVSRDDSKNTLYLQMNSLKTEDTAVYYCTAGTGRTDHDYWGQGTLVTVSS
213
236
288
317
432
464
DIVMTQSPDSLAVSLGERATINCKSSQSVLYSSNNKNFLAWYQQKAGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYMTPLTFGGGTKVEIK
169
204
256
264
373
399
QVQLQESGPGLVKPSETLSLTCTVSGYSISSGYYWGWIRQPPGKGLEWIGSIYHSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARDLNSGLIDYWGQGTLVTVSS
173
199
251
271
386
418
QSVLTQPPSASGTPGQRVTISCSGSSSNIGSNYVYWYQQLPGTAPKLLIYRNNQRPSGVPDRFSGSKSGTSASLAISGLRSEDEADYYCAAWDDSLSVLFGGGTKLTVL
180
203
255
263
372
401
EVQLVESGGGLIQPGGSLRLSCAASGFTVSSNYMSWVRQAPGKGLEWVSVIYSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARLRRDGYNSWDWFDPWGQGTLVTVSS
242
265
317
337
452
499
DIQMTQSPSTLSASVGDRVTITCRASQSISSWLAWYQQKPGKAPKLLIYKASSLESGVPSRFSGSGSGTEFTLTISSLQPDDFATYYCQHRHTFGQGTKLEIK
172
189
241
249
358
372
EVQLVESGGGLVQPGGSLRLSCAASGFTVSSNYMSWVRQAPGKGLEWVSVIYSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARANRGAGFSTVPMRDKGFFAFDIWGQGTMVTVSS
212
235
287
307
422
493
EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWPPGITFGQGTRLEIK
175
192
244
252
361
393
QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYDINWVRQATGQGLEWMGWMNPNSGNTGYAQKFQGRVTMTRNTSISTAYMELSSLRSEDTAVYYCARFTPKEPDYFDYWGQGTLVTVSS
191
214
266
289
404
442
DIQMTQSPSSLSASVGDRVTITCRASQGIRNDLGWYQQKPGKAPKRLIYAASSLQSGVPSRFSGSGSGTEFTLTISSLQPEDFATYYCLQHNSYPWTFGQGTKVEIK
165
182
234
242
351
377
QVQLVQSGSELKEPGASVKVSCRASGYSFTSYAVNWVRLAPGQGLEWMGWINTDTKNPTYARDFTGRFVFSLDTSVDTAYLQISSLRAEDTAVYYCARHSAALGLPDYWGQGTLVTVSS
182
205
257
280
395
430
DIQMTQSPSSLSASVGDRVTITCRASQPFSNYLAWYQQKPGKVPQLLIYSASTLQSGVPSRFSGSGSWTTFTLTINNLQPEDAATYYCQKHNSAPLTFGQGTKVEIE
172
189
241
249
358
384
EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSKTDGGTTDYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTAVYYCTTDRVVVVAATGYYYYGMDVWGQGTTVTVSS
213
236
288
317
432
491
SYELTQPPSVSVSPGQTASITCSGDKLGDKYACWYQQKPGQSPVLVIYQDSKRPSGIPERFSGSNSGNTATLTISGTQAMDEADYYCQAWDSSTVFGGGTKLTVL
170
187
239
247
356
379
EVQLVQSGAEAKKPGESLRISCKTSGYSFSSYWIGWVRQMPGKGLEWMGNFYPGDSDTRYSPSFQGQVTISADWSITTAYLQWSSLKASDTAIYYCARGLYYSFLTGHYNGNVAFDIWGQGTMVTVSS
192
215
267
290
405
467
DIVMTQSPDSLAVSLGERATINCRSSQSVLYSSNSKNYLAWYQQKPGQPPKLLIYWASTRESGVPERFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSNPYTFGQGTKVEIK
169
204
256
264
373
399
DVQLVESGGGLVKPGGSLRLSCVASGFTFSRQSMHWVRQAPGKGLEWVSSITSRSDFIYYRDSVKGRFTISRDNARNSLFLQMTSLRAEDTAVYYCARDETTLGGDWGRGTLVTVSS
212
235
287
310
425
454
QSVLTQPPSASGTPGQRVTISCSGSSSNIGSRTVNWYQQLPGTAPRLFIYNNNQRPSGVPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDVSLSGWVFGGGTKLTVL
180
203
255
263
372
404
QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYYMHWVRQAPGQGLEWMGIINPSGGSTSYAQKFQGRVTMTRDTSTSTVYMELSSLRSEDTAVYYCARGATMVRGRIDPWGQGTLVTVSS
191
214
266
289
404
442
QSALTQPPSASGSPGQSVTISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYEVSKRPSGVPDRFSGSKSGNTASLTVSGLQAEDEADYYCSSYAGSNNLVFGGGTKLTVL
174
200
252
260
369
398
QVQLQESGPGLVKPSETLSLTCSVSGYSITSGHYWGWIRQSPEKGLEWIGSIYKSGTTYYNPTLNSRVTMSVDTSKNQFSLNLSSVSASDTAVYYCARGRQWLMYYFDYWGQGALVTVSS
174
200
252
272
387
425
EIVLTQSPGTLSLSPGESATLSCRASQSVSTTYLAWYQQRPGQAPRLLIYGGSGRATDIPDRFTGSGSGTDFTLTISRLEPEDFGVYYCQQYGSSVTFGGGTKVEIK
191
211
263
271
380
403
QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYAISWVRQAPGQGLEWMGGIIPIFGTANYAQKFQGRVTITADESTSTAYMELSSLRSEDTAVYYCARDQGFELWLLYYWGQGTLVTVSS
191
214
266
289
404
442
DIVMTQSPDSLAVSLGERATINCKSSQSVLYSSNNKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSTPRTFGQGTKLEIK
169
204
256
264
373
399
EVQLLESGGGLVQPGGSLRLSCAASGFTFRNYAMSWVRQAPGKGLEWVSAVRGSGNDPYYADSVKGRFTISRDNSRNTLYLQMNSLRAEDTAVYYCAKILTTVTTFEYFQDWGQGTLVTASS
212
235
287
310
425
469
DIQMTQSPSSVSASVGDRVTITCRATEDINNWLAWYQQEPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISGLQPEDFATYYCQQAKSFPLTFGGGTKVEIK
172
189
241
249
358
384
EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYSMNWVRQAPGKGLEWVSSISSSSSYIYYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARGAYMVRGVSHHYYYYMDVWGKGTTVTVSS
212
235
287
310
425
484
EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSPWTFGQGTKVEIK
183
203
255
263
372
398
EVQLVESGGGLVPPGGSLTLSCAASGFTLSNYWLYWVRQSPGKGLEWVAYFKGDGSSTKFADSVKGRFTFSRGNARNILYLQMNNLRAEDTAMYYCARDGPAIMVDFDFWGRGTLVTVSS
203
226
278
301
416
454
DIVMTQAPLSLPVTPGEPASISCRSSQSLLHSSGYNFLDWYLQKPGQSPQLLIYLGSSRASGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCMQALQAPITFGQGTRLEIK
174
206
258
266
375
401
QVQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAPGQGLEWMGRINPNSGGTNYAQKFQGRVTMTRDTSISTAYMELSRLRSDDTAVYYCAVGRIYDSSGYYALAGYFDYWGQGTLVTVSS
197
220
272
295
410
469
EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSPLTFGGGTKVEIK
183
203
255
263
372
398
QITLKESGPTLVKPTQTLTLTCTFSGFSLSTSGVGVGWIRQPPGKALEWLALIYWNDDKRYSPSLKSRLTITKDTSKNQVVLTMTNMDPVDTATYYCAHSAGEILDFDYWGQGTLVTVSS
157
186
238
258
373
408
QSALTQPPSASGSPGQSVTISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYEVSKRPSGVPDRFSGSKSGNTASLTVSGLQAEDEADYYCSSYAGSNLRVFGGGTKLTVL
174
200
252
260
369
398
QVQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAPGQGLEWMGWINPNSGGTNYAQKFQGRVTMTRDTSISTAYMELSRLRSDDTAVYYCARAPRFGFWSGYSYGMDVWGQGTTVTVSS
197
220
272
295
410
463
QSALTQPASVSGSPGQSITISCTGTSSDVGGYNYVSWYQQHPGKAPKLMIYEVSNRPSGVSNRFSGSKSGNTASLTISGLQAEDEADYYCSSYTSSSTYVFGTGTKVTVL
174
200
252
260
369
398
QVQLQESGPGLVKPSQTLSLTCSVSGGSIRSGGYHWNWIRQCPGKGLEWIGYIDDRGNTEYDASLRSRGVISVDRSLKQFSLRLTSVTAADTAVYYCARDKDETGIGSFDQWGRGTLVTVSS
193
222
274
294
409
450
DIVMTQSPDSLAVSLGERATISCKSSQSILNRSNNKNYLAWYQQKPGQPPKLLVYWASTRESGVPDRFSGSGSGTDFTLSISSLQAEDVAVYYCQHYFSRPFTFGQGTKLEIK
169
204
256
264
373
399

Paired SARS-COV-2 heavy/light chain sequences from the Observed Antibody Space database

Human paired heavy/light chain amino acid sequences from the Observed Antibody Space (OAS) database obtained from SARS-COV-2 studies.

https://opig.stats.ox.ac.uk/webapps/oas/

Please include the following citation in your work:

 Olsen, TH, Boyles, F, Deane, CM. Observed Antibody Space: A diverse database of cleaned, annotated, and translated unpaired and paired antibody sequences. Protein Science. 2022; 31: 141–146. https://doi.org/10.1002/pro.4205

Data Preparation

This data was obtained on August 3, 2023 by searching the OAS Paired Sequence database with the following criteria:

  • Species = "human"
  • Disease = "SARS-COV-2"

This returned 704,652 filtered sequences from 3 studies split across 63 .csv.gz data unit files. These were extracted and filtered for records where both the complete_vdj_heavy and complete_vdj_light values were "T". Finally, the sequence_alignment_aa_heavy and sequence_alignment_aa_light fields were extracted into dataset and a 90/10 train/test applied. The resulting data was saved in pyarrow format.

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