Steroid resistance nephrotic syndrome is defined as failure to achieve remission after:-: (A) 4 weeks of daily Coicosteroid therapy, (B) 6 weeks of daily Coicosteroid therapy, (C) 8 weeks of daily Coicosteroid therapy, (D) 12 weeks of daily Coicosteroid therapy
Answer is C. NELSON : Steroid Resistance. Steroid resistance is defined as the failure to achieve remission after 8 wk of coicosteroid therapy. GHAI 9E : Steroid resistance is diagnosed, if there is lack of remission despite treatment with prednisolone, at a dose of 2 mg/kg/day(60mg/m2/day)for 4weeks followed by 1.5mg/kg (40 mg/m2) on alternate days for another4 weeks Nephrotic syndrome (NPHS2-related), also known as steroid-resistant nephrotic syndrome