Cause of vasodilation in spider nevi: (A) Testosterone, (B) Estrogen, (C) FSH, (D) Hepatotoxin
Answer is B. B i.e. EstrogenIn chronic liver disease (especially cirrhosis) and pregnancy, impaired estrogen metabolism and consequent hyper estroenemiaQ leads to spider angiomata/nevi (superficial, toous aerioles, that unlike simple telangiectases, typically fill from the center outwards and occur invariably on upper half of body) and palmar erythema (mottled redness of thenar & hypothenar eminences).