Treatment of pustular psoriasis is:-: (A) Thalidomide, (B) Hydroxyurea, (C) Retinoids, (D) Steroids
Answer is C. Most cases of GPP (Generalised Pustular Psoriasis) require systemic therapy. Retinoids--> TOC Response to high doses of acitretin (1 mg/kg/day) is rapid and lower doses of 0.5-0.75 mg/kg/day, sufficient to maintain control. Acitretin> Methotrexate Other drugs used are Cyclosporine ,Colchicine, Razoxane, Dapsone TNF-antagonists, and Basiliximab, an antibody directed at the IL-2 receptor, rapidly control acute GPP. Systemic steroids are C/I in psoriasis.