Which one of the following anti-hypeensive drugs is contraindicated in pregnancy?: (A) Alpha methyldopa, (B) Hydralazine, (C) Nifedipine, (D) Frusemide
Answer is D. Diuretics in pregnancy- In a PIH patient, furosemide is C/I as an anti-hypeensive because in PIH the intravascular volume is low. Thats because the pathology is Vasospasm and hence there is intravascular 'Low vloume'. Giving a diuretic would fuher decrease the intravascular volume and hence reduce the placental perfusion. However, in a pregnant female with Hypeension of pregnancy complicated with CHF/Pulmonary edema, then diuretics can be used