A 60 year old man with progressive dementia of recent onset presents with intermittent irregular jerky movemets. EEG shows periodic sharp biphasic waves. The most likely diagnosis is:: (A) Alzheimer's disease, (B) Creutzfeldt Jakob disease, (C) Lewy body dementia, (D) Herpes Simplex Encephalitis
Answer is B. Answer. is B (Creutzfeldt Jakob disease) : The combination of progressive dementia, irregular jerky movements (myoclonus / choreoathetoid movements) in association with a characteristic EEG pattern (periodic sharp biphasic waves) suggests a diagnosis Creutzfeldt Jakob Disease.