Levosulpiride acts as an antagonist of which central dopamine receptor: (A) D1, (B) D2, (C) D3, (D) D4
Answer is B. D2 receptor antagonists being explored as prokinetic agents include levosulpiride, the levo-enantiomer of sulpiride Levosulpiride is claimed to have mood elevating propeies. Levosulpiride is used in the treatment of psychoses, paicularly negative symptoms of schizophrenia, anxiety disorders, dysthymia, veigo, dyspepsia, irritable bowel syndrome and premature ejaculation. Ref: G&G 12e pg:1506