Posterior column sensations in lower limbs are lost in :: (A) Vitamin A deficiency, (B) Vitamin B12 deficiency, (C) Vitamin C deficiency, (D) Vitamin D deficiency
Answer is B. Deficiency of vitamin B12 leads to megaloblastic anemia which is indistinguishable from folic acid deficiency.
Deficiency also have manifestations related to loss of myelin-like subacute combined degeneration of spinal cord (symptoms of lesions of a posterior column like loss of vibration and proprioception, paraesthesias, depressed stretch reflexes and mental changes like poor memory and hallucinations etc.)