Risk of transplacental transmission of toxoplasma gondii is maximum when mother is infected:: (A) Prior to conception, (B) During first trimester, (C) During second trimester, (D) During third trimester
Answer is D. Risk of fetal infection in acute maternal toxoplasmosis increases with each trimester of pregnancy being 15%, 25% and 60% in 1st, 2nd and 3rd trimesters respectively But severity of fetal infection is much greater in early pregnancy.