Which of the following is the best test for diagnosis of paroxysmal nocturnal hemoglobinuria?: (A) Sucrose lysis test, (B) Ham test, (C) Flow cytometry, (D) Bone marrow aspiration
Answer is C. - Best investigation for diagnosing PNH - Flaer flow cytometry - Biphenotypic cells are seen - Other investigations used are: Ham's acidified serum test Sucrose lysis test