Clara cells are seen in:: (A) Bronchoalveolar cell Ca, (B) Small cell Ca, (C) Squamous cell Ca, (D) Non small cell Ca
Answer is A. Ans: a (Bronchoalveolar cell Ca) Ref: Robbins, 7th ed, p. 761Clara cells are seen in bronchoalveolar carcinomaBronchoalveolar cell Ca1 -9% of lung tumoursAffect terminal bronchoalveolar regionsGrowth pattern is referred to as "Lepdic"Types:Non mucinous - Columnar, peg shaped or cuboidal cellsMucinous - Distinct columnar with cytoplasmic & intra-alveolar mucinAerogenous spread presentG/A: Single or multiple nodules coalescing to form pneumonia like consolidationM/E: Mucin secreting bronchoalveolar cellsClara cellsType II pneumocytes.