Blood of 45 yrs old male shows -HVA. This patient is most likely to show -: (A) PCC, (B) Schizophrenia, (C) Depression, (D) Parkinson's ds
Answer is C. Some guides have given Schizophrenia as the answers. But they are wrong. Read below : -
Homovanillic acid (HVA) is the major metabolite of dopamine.
Schizophrenia is characterized by hyperactivity of dopaminergic system. However, HVA is not raised in Schizophrenia → Which questioned the dopamine hypothesis of schizophrenia.
Dopamine is decreased in parkinsonism →HVA level is decreased.
Though dopamine is decreased in depression, dopamine and HVA are raised in psychotic depression: -"Elevated levels of HVA have been reported in psychotic depression, suggesting increased dopamine activity in this subtype of depression"

Imidazole acetic acid