Therapeutic drug monitoring of plasma concentration of antihypeensive drugs is not practiced because: (A) Determination of plasma level of these drugs is quite tedious and long process, (B) It is easier to measure the effect of these drugs, (C) Antihypeensive effect do not increases linearly with the dose, (D) All Antihypeensive drugs are prodrugs
Answer is B. Ref-KDT 6/e p34 TDM is done for drugs (with narrow therapeutic index) whose response cannot be monitored by clinical examination. Antihypeensive effect can be easily measured, therefore TDM is not required