Good pasture&;s syndrome is characterised by-: (A) Necrotisting hemorrhagic interstitial pneumonitis, (B) Alveolitis, (C) Patchy consolidation, (D) Pulmonary edema
Answer is C. The lungs are heavy and have areas of red-brown consolidation due to diffuse alveolar hemorrhage. Microscopic examination shows focal necrosis of alveolar walls associated with intraalveolar hemorrhage, fibrous thickening of septa, and hyperophic type II pneumocytes. There is abundant hemosiderin due to earlier episodes of hemorrhage. The characteristic linear pattern of immunoglobulin deposition (usually IgG, sometimes IgA or IgM) that is the hallmark diagnostic finding in renal biopsy specimens also may be seen along the alveolar septa. Ref: ROBBINS BASIC PATHOLOGY 10th ed Pg no: 519