Lymphohistiocytic variant of Reed Sternberg cell is seen in which of the following?: (A) Lymphocyte rich HL, (B) Lymphocyte predominant HL, (C) Nodular sclerosis HL, (D) Mixed cellularity HL
Answer is B. L-H type of Reid Steinberg (RS cell) - Non classical variant of HL (CD15-ve, CD30-ve) Lymphocyte predominant HL - best prognosis Nodular sclerosis HL - lacunar R-S cell (common subtype all around the world) Lymphocyte predominance type expresses B cell markers and is not associated with EBV