Progressive transformation of germinal centres is a precursor lesion of:: (A) Hodgkins lymphoma ,nodular sclerosis, (B) Hodgkins lymphoma,mixed cellularity, (C) Anaplastic large cell lymphoma, (D) Peripheral T cell lymphoma
Answer is A. Progressive transformation of germinal centres is a beningn reaction pattern in lymphnodes.it is most often associated with reactive follicular hyperplasia. It is also associated with nodular sclerosis and lymphocyte predominant Hodgkins lymphoma.( ref Loachims lymphnode pathology /186)