Adverse effect of Tacrolimus include all of the following, EXCEPT:: (A) Neurotoxicity, (B) Nephrotoxicity, (C) Diabetes, (D) Hirsutism
Answer is D. Tacrolimus causes Neurotoxicity (tremors, seizures, hallucination and coma), Nephrotoxicity and precipitates diabetes and can cause alopecia and diarrhea, but does not cause hirsutism. Ref: Harrison's Principles of Internal Medicine, 17th Edition, Page 1987; Lippincott's Illustrated Reviews: Pharmacology, 4th Edition, Pages 413, 489, 498