Complement binding immunoglobulin the classical pathway is -: (A) IgG & IgM, (B) IgG & IgA, (C) IgG & IgD, (D) IgD & IgE
Answer is A. IgM is paicularly effective at complement activation by binding to C1. IgG activates the classical pathway of the complement system, a cascade of immune protein production Ref: Ananthanarayan & Parker's textbook of microbiology 9th edition pf:98