Failure of the choroid fissure to close results in: (A) Congenital detached retina, (B) Congenital aniridia, (C) Congenital aphakia, (D) Coloboma iridis
Answer is D. Failure of the choroid (optic) fissure to close results in a cleft of the iris--called coloboma iridis (mostly in inferonasal position). This defect may extend into the ciliary body, choroid, optic nerve, or retina. Congenital aphakia--absence of the lens--may result from defective development of the lens placode.