Which of the interleukins is responsible for endogenous pyrexia in a young lady admitted on the medical ward?: (A) IL1, (B) IL6, (C) INF gamma, (D) IFN alpha
Answer is A. IL1 also konwn as endogenous pyrogen causes fever by inducing the production of prostaglandin E2 which acts on the hypothalamus and induce a fever like reaction. IL 1 is produced by macrophages.