The Nitrate which does not undergo first pass metabolism is -: (A) Isosorbide mononitrate, (B) Nitroglycerine, (C) Pentaerythritol tetranitrate, (D) Isosorbide dinitrate
Answer is A. Ans. is 'a' i.e., Isosorbide mononitrate o "All nitrates except isosorbide mononitrate undergo extensive but variable first pass metabolism in liver".