Most common enzyme deficiency leading to childhood hypertension is –: (A) 17–Alpha hydroxylase, (B) 21–Beta hydroxylase, (C) 11–Beta hydroxylase, (D) 3–Beta hydroxy steroid dehydrogenase
Answer is C. Salt retention and hypertension is seen in 17-α hydroxylase deficiency and 11-β hydroxylase deficiency.
11-β hydroxylase deficiency is more common.
17-α hydroxylase deficiency is an uncommon form of congenital adrenal hyperplasia.