For the following dyslipidemias, select the most characteristic finding.Type III hyperlipoproteinemia.: (A) palmar plane xanthomas, (B) triglycerides > 1000, (C) subcutaneous extensor tendon xanthomas, (D) low serum cholesterol
Answer is A. In the rare familial form, raised yellow plaques appear on palms and fingers, and reddish-yellow xanthomas occur on the elbows. This disorder is felt to be secondary to accumulation of abnormal chylomicron and very low-density lipoprotein (VLDL) remnants. It is probably due to inherited homozygous defects in Apo E-II structure.