A defect in the enzyme hexosaminidase causes: (A) Gaucher disease, (B) Farber disease, (C) Tay-Sachs disease, (D) Krabbe disease
Answer is C. DiseaseEnzyme DeficiencyClinical SymptomsTay-Sachs disease Hexosaminidase AMental retardation, blindness, muscular weaknessRef: Harper&;s Biochemistry; 30th edition; Chapter 24 Metabolism of Acylglycerols & Sphingolipids