The drug which is used for long term maintenance in opioid addiction:: (A) Naloxone, (B) Nalorphine, (C) Butarphamol, (D) Methadione
Answer is D. D i.e. Methadone Naloxone is used in opioid overdoseQ and ultrarapid detoxification of opioid dependent (addicts)Q. Due to sho duration of action (t1/2 = 1-2 hour), frequent dosing is required, which makes it unsuitable for maintenance treatmentQ. Naltrexone & Nalmefene are used in rapid detoxification and maintenance of ultrarapid detoxification in opioid addicts (dependent). And methadone is used in sho term detoxification, long term detoxification & long term maintenance in opioid dependant (addicts)Q.