Chediak higashi syndrome, true is -: (A) Defect in phagocytosis, (B) Neutropenia, (C) Agammaglobulinemia, (D) IgA defficiency
Answer is A. Chediak-Higashi syndrome is autosomal recessive disorder. Polymorphonuclear leucocytes here possess larger lysosomes. These abnormal lysosomes do not fuse with phagosome. - this leucocytes posses diminished phagocytic activity. Reference : Baveja text book of microbiology, 4th edition, pg no:153 <\p>