Mode of action of depolarizing and non-depolarizing neuromuscular blocker?: (A) Depolarizing - no repolarization, non-depolarizing - competitive inhibition, (B) Both competitive inhibitors, (C) Non-depolarizing - no repolarization; depolarizing - no depolarizin, (D) Depolarizing - persistent depolarization no depolarizing - no repolarization
Answer is A. Depolarizing neuromuscular block-persistent depolarization / no repolarization Non depolarizing - competitive inhibition Succinylcholine is the only depolarising neuromuscular blocker rest all neuromuscular blocker in clinical use are nondepolarising neuromuscular blocker.