Use of tamoxifen in carcinoma of breast patients does not lead to the following side effects.: (A) Thromboembolic events, (B) Endometrial Carcinoma, (C) Cataract, (D) Cancer in opposite breast
Answer is D. Ans. is 'd' i.e. Cancer in opposite breast Adverse effects of Tamoxifen: - Hot flushes, nausea vomiting (most common side effects)*Menstrual irregularities, vaginal bleeding, discharge, pruritus vulvae & dermatitisEndometrial cancerThromboembolismCataractsRetinal deposits & decreased visual acuityUses of Tamoxifen: -Estrogen receptor positive breast cancer: used in both pre and postmenopausal women.May slow the development of osteoporosis in postmenopausal women (due to its estrogenic effect)