True about Gilbe syndrome is:: (A) Conjugated hyperbilirubinemia, (B) Starvation improves the condition, (C) Phenobarbitone improves the condition, (D) Life-threatening
Answer is C. Gilbe syndrome: Unconjugated hyperbilirubinemia Paial deficiency of UDPglucuronyl transferase enzyme Jaundice precipitated by fasting Phenobarbitone, being an enzyme inducer, improves the condition by increasing the activity of UDP glucuronyl transferase enzyme