All of the following statements about nesiritide except: (A) It is a BNP analogue, (B) It can be used decompensated CHF, (C) It can be administered orally, (D) It causes loss of Na+ in the urine
Answer is C. (Ref CMBT 2014/396; KDT 6/e p507) Nesiritide is a recombinant BNP. It produces vasodilation and natriuresis. It has to be administered by iv. route. because being a peptide, it is metabolized by peptidases in GT It is used for acutely decompensated hea failure.