A patient presented with oral mucosal lesions and flaccid blisters Over skin. It detects what and which pattern under microscopic examination?: (A) Fishnet pattern IgG in epidermis, (B) IgG at Dermo-epiderrnal juction, (C) IgA at Dermo-epidermal junction, (D) IgG in dermis
Answer is A. In pemphigus vulgaris skin involvement stas in the form of flaccid blisters. Cutaneous lesions are usually preceded by blisters and erosions of oral mucosa In Direct immunofluorescence intercellular IgG -fishnet pattern throughout the epidermis is seen in pemphigus vulgaris. page no.280,287 Reference IADVL's concise textbook of dermatology