All are impoant laboratory features of hereditary spherocytosis, EXCEPT:: (A) Reduced MCHC, (B) Normocytic anemia, (C) Positive pink test, (D) Normal WBC count
Answer is A. Laboratory diagnosis of hereditary spherocytosis The anemia is usually normocytic. Increase in mean corpuscular hemoglobin concentration (MCHC)- (The only condition in which an increased MCHC is seen.) The diagnosis is on the basis of red cell morphology and osmotic fragility, a modified version called the pink test. Ref: Harrison, E-18, P-875.