Which of the following drugs is effective against HIV with Y181C mutation?: (A) Festinavir, (B) Lersivirine, (C) Elvitegravir, (D) Dolutegravir
Answer is B. Lersivirine
Festinavir is a NRTI shown to be effective in adefovir and tenofovir resistance
Lersivirine is a NNRTI effective against HIV with Y181C mutation
Elvitegravir is a integrase inhibitor used for initial / naïve treatment
Dolutegravir is a integrase inhibitor approved for raltegravir-resistant infections