Diffuse multiple bone involvement, cafe-au-lait pigmentation and endocrine disturbances are the features of:: (A) McCune Albright syndrome, (B) Jaffe's syndrome., (C) Mazabrauds syndrome, (D) All of the above
Answer is A. Polyostotic Fibrous dysplasia is of 2 types. In Jaffe type there is multiple bone involvement associated with cafe-au-lait spots. Extreme or diffuse multiple bone involvement, cafe-au-lait pigmentation, and endocrine disturbances are important features of McCune-Albright's syndrome. In polyostotic form, the curvature of femoral neck and proximal shaft of the femur increase markedly causing a shepherd's crook deformity.