Massive transfusion in healthy adult male can cause hemorrhage due to: March 2011: (A) Increased tPA, (B) Dilutional thrombocytopenia, (C) Vitamin K deficiency, (D) Decreased fibrinogen
Answer is B. Ans. B: Dilutional thrombocytopenia Massive blood transfusion causes dilutional coagulopathies especially dilutional thrombocytopenia (stored blood has no platelets and concentration of other clotting factors is also very less)