Which of the following is the most common complication of immunosuppression: (A) Graft rejection, (B) Malignancy, (C) Thrombocytopenia, (D) Infection
Answer is D. Immunosuppressive therapy impairs the protective response to both malignancy and infection. Consequently, pre-existing malignancy is an absolute contraindication and, even after curative treatment, transplantation should not usually be considered for at least 3 years. Similarly, the presence of active infection is a contraindication to transplantation In immunosupressive states , infection is the most common complication due to weakened immune systems . Ref Bailey and love 27e Transplantations chapter p1541