In patients with hyperophic cardiomyopathy maximum mutations are found in which gene:: (A) . b - myosin heavy chain, (B) Elastin, (C) . a - tropomyosin, (D) Troponin T
Answer is A. b - Myosin heavy chain Mutations in gene for b - Mysoin heavy chain are associated with 40% of the families with hyperophic cardiomyopathy. Troponin T mutations - 15% of the families a - tropomyosin mutations ~5% of the families