Renal papillary necrosis is seen in: (A) Sickle cell disease, (B) Gouty nephropathy, (C) Chronic glomerulonephritis, (D) Tumor necrosis syndrome
Answer is A. Necrotizing papillitis (or papillary necrosis): It is one special pattern of acute pyelonephritis and is much more frequent in diabetics Hyaline aeriolosclerosis narrows blood vessels -> reduces the blood supply to the renal medulla -> ischemia ->causes necrosis of the tips of papillae (papillary necrosis). Causes of necrotizing papillitis: Diabetes mellitus Sickle cell anemia Analgesic nephropathy Obstructive uropathy. Ref: RAM DAS NAYAK EXAM PREPARATORY MANUAL FOR UNDERGRADUATES 2nd ed. pg no: 615