Tangier disease is characterized by: (A) Low HDL, (B) Defective LDL receptors, (C) No chylomicrons, (D) Overproduction of VLDL
Answer is A. DyslipoproteinemiasDefectRemarksFamilial alpha-lipoprotein deficiencyTangier diseaseFish-eye diseaseApo-A-I deficienciesAll have a low or near absence of HDLA tendency toward hyperiacylglycerolemia as a resultof the absence of apo C-ll, causing inactive LPL. Low LDLlevels. Atherosclerosis in the elderlyRef: Harper&;s biochemistry; 30th edition; Chapter 26; Cholesterol Synthesis, Transpo, & Excretion