Statins inhibit which of the following enzyme -: (A) HMG CoA reductase, (B) HMG CoA synthetase, (C) HMG CoA oxidase, (D) Acetyl CoA synthetase
Answer is A. Ans. is 'a' i.e., HMG CoA reductase * Statins (Lovastatin) competitively inhibit the conversion of HMG-CoA to mevalonate (rate limiting step in cholesterol synthesis) by inhibiting the enzyme HMG-CoA reductase.