Maximum extrapyramidal side-effect is seen with:: (A) Haloperidol, (B) Chlorpromazine, (C) Imipramine, (D) Clomipramine
Answer is A. Ans. A. HaloperidolTypical antipsychotic drugs are known to cause extrapyramidal side effects. They block D2 receptors. They are of two types: high potency and low potency. High potency drugs like haloperidol are known to cause maximum EPS. Low potency drugs like chlorpromazine have alpha blocking properties and show anticholinergic side effects.