Crizotinib is used in the treatment of :: (A) FLT-3 +ve Non small cell carcinoma of lung, (B) ALK +ve Non small cell carcinoma of lung, (C) FLT-3 +ve  Acute myeloid leukemia, (D) BRCA-2 +ve metastatic breast carcinoma
Answer is B. Crizotinib inhibits anaplastic lymphoma kinase (ALK), hence used in ALK mutation positive non small cell carcinoma of lungs.