The enzyme defect in galactosemia is: (A) Aldose reductase, (B) Galactose-1-phosphate uridyltransferase, (C) Galactokinase, (D) Aldolase B
Answer is B. Inability to metabolize galactose occurs in the galactosemias, which may be caused by inherited defects of galactokinase, uridyl transferase, or 4-epimerase Though deficiency of uridyl transferase is best known.Harper 30th edition pg: 205