There is mutation of gene coding for the ryanodine receptors in malignant hypehermia. Which of the following statements best explains the increased heat production in malignant hypehermia?: (A) Increased muscle metabolism by excess of calcium ions, (B) Thermic effect of blood, (C) Increased sympathetic discharge, (D) Mitochondria thermogenesis
Answer is A. A i.e. Increased muscle metabolism by excess of Ca2+ ions