Lesion is Alzheimer's disease are commonest at: (A) Aniygdala, (B) Nucleus of Meynes, (C) Pineal gland, (D) Prefrontal sulcus
Answer is B. Nucleus basalis of Meyne for Alzheimer's disease and Parkinson's disease dementia. The nucleus basalis of Meyne (NBM) is a large source of cholinergic innervation to widespread coical areas. There have been two repos of DBS of the NBM for either AD or PD. Ref Harrison20th edition pg 2456