What is role of insulin in lipid metabolism?: (A) Activate lipoprotein lipase, (B) Increase lipolysis, (C) Activate hormone sensitive lipase, (D) Activate acetyl CoA carboxylase
Answer is D. Lipogenesis is oured by providing more acetyl CoA by pyruvate dehydrogenase reaction. Insulin increases the activity of acetyl CoA carboxylase and provides glycerol for esterification of fatty acids to TAG.Ref: DM Vasudevan - Textbook of Biochemistry for Medical Students, 7th edition, page no: 321