Which of the following statements is true regarding peussis ?: (A) Neurological complication rate of DPT is I in 50000, (B) Vaccine efficacy is more than 95%, (C) Erythromycin prevents spread of disease between children, (D) The degree of polymorphonuclear Leukocytosis correlates with the severity of cough
Answer is C. Ans. is 'c' i.e., Erythromycin prevents spread of disease between children o Efficacy of Peusis Vaccine - repoed to be from 70-90% o Risk of acute encephalopathy - is 1 in 40, 000 cases following DTP vaccine. o Peusis toxin produces Lymphocytosis & not polymorphonuclear Leukoctyosis. Leukocytosis due to absolute lymphocytosis is characteristic in late catarrhal or paraoxysmal stage. o Prophylactic erythromycin prevents infecting bacteria to become established - prevents spread of disease - Park