16-year-old girl with sho height, amenorrhea with widely spaced nipple. Karyotyping is;: (A) 45 X0, (B) 46 XO, (C) 47 XXX, (D) 46XY
Answer is A. Given features suggests the diagnosis of Turner's syndrome. Turner's syndrome Most common sex chromosomal disorder in phenotypic females. Results from complete or paial loss of one X chromosome (45, XO) Features: Sho stature Coarctation of aoa Cubitus valgus Streak ovaries, infeility, amenorrhea Peripheral lymphedema at bih Low posterior hairline Webbing of neck Broad chest and widely spaced nipples