Oxidative phosphorylation couples generation of ATP with which of the following?: (A) Proton translocation, (B) Substrate level phosphorylation, (C) Electron flow through cytochromes, (D) None of the above
Answer is A. Proton translocation across the mitochondrial membrane generates an electrochemical potential difference composed of a pH gradient and an electrical potential. This electrochemical potential difference is used to drive ATP synthase to form ATP.