A 2-year-old male has developmental delay kinke hair and weak muscle tone. What is the diagnosis?: (A) Wilson's disease, (B) Menkes disease, (C) Zinc deficiency, (D) Cerebral palsy
Answer is B. ANS. BMenkes disease, also known as Menkes syndrome, is an X-linked recessive disorder that affects copper levels in the body, leading to copper deficiency (ATB 7A gene on chromosome 13).Signs and symptoms of this disorder include:1. Weak muscle tone (hypotonia)2. Sagging facial features3. Seizures4. Intellectual disability and developmental delay5. Brittle hair6. Metaphyseal widening.Menkes diseaseImage of zinc deficiency (acrodermatitis enteropathica)