About cetirizine all are true except-: (A) It is a 2nd generation anti histaminic, (B) It is a metabolite of hydroxyzine, (C) Good CNS penetration, (D) Inhibits release of histamine
Answer is C. Ans. is 'c' i.e., Good CNS penetration Cetrizine* Cetrizine is a 2nd generation anti histaminic* It is a metabolite of hydroxyzine with marked affinity for the peripheral H1 receptors,* It penetrates CNS poorly and has mild sedating effect.* It inhibits release of histamine from mast cells and therefore has been used for urticarial and atopic dermatitis.* It is non - arrhythmogenic.