Which of the following statements about changes in aicular cailage with ageing is not true:: (A) Total proteoglycan content is decreased, (B) Synthesis of proteogycans is decreased, (C) Enzymatic degradation of proteoglycans is increased, (D) Total water content of cailage is decreased
Answer is C. Cailage propey Aging Osteoahritis Hydration Decreased Increased ( in late OA its also decreased) Proteolytic enzymes Normal Increased Proteoglycan content Decreased(due to decreased synthesis) Decreased (due to increased destruction)