Dose of drug require no or minor adjustment in renal failure, except -: (A) Doxycycline, (B) Vancomycin, (C) Chloramphenicol, (D) Clindamycin
Answer is B. Ans. is 'b' i.e., Vancomycin o Vancomycin causes renal toxicity which is dose related therefore significant dose reduction is needed in renal failure. o Rest of the drugs asked in the question are metabolised mainly in liver therefore no adjustment needed in renal failure.