All of the following are required for hydroxylation of proline in collagen synthesis except -: (A) O2, (B) Vitamin C, (C) Dioxygenases, (D) Pyridoxal phosphate
Answer is D. Hydroxylation of proline and lysine during collagen synthesis requires vitamin C (ascorbic acid), molecular oxygen (O2), α-ketoglutarate and enzymes dioxygenases (prolyl hydroxylase, lysyl hydroxylase).