A patient presented with a platelet count of 700 x 109/L with abnormalities in size, shape and granularity of platelets. WBC count of 8 x109 L, hemoglobin of 12 g/dl and the absence of the Philadelphia chromosome. The most likely diagnosis would be?: (A) Polycythemia vera, (B) Essential thrombocythemia, (C) Chronic myeloid leukemia, (D) Leukemoid reaction
Answer is B. A patient presents with thrombocytosis with abnormalities in size, shape and granularity of platelets, with normal WBC count & hemoglobin and the absence of the Philadelphia chromosome. The most likely diagnosis in this case would be Essential Thrombocythemia