Interferon gamma, which is known to enhance the cytotoxic effects of macrophages are secreted by which of the following components of the immune system?: (A) CD4 T cell, (B) CD8 cells, (C) RBC, (D) Neutrophils
Answer is A. CD4+ Thl T cells secrete interferon gamma, a cytokine that enhances the cytotoxic potential of activated macrophages. These activated macrophages show increased phagocytic and respiratory activity, along with enhanced antigen presenting capacity.