EAC rosette formation is the propey of one of the following type of immune cells -: (A) T cells, (B) B cells, (C) Macrophages, (D) All of the above
Answer is A. Erythrocyte antibody complement rosetting (EAC-rosetting), occurs when antibody in the presence of complement is bound to the surface of a red blood cell. The complement binds to the tail region (Fc region) of the antibody. Finally T-cells with a complement receptor are added and the T-cells bind to the complement on the antibody completing the rosette Reff : www.mayoclinic.com