Itching during cholestasis of pregnancy is due retained :: (A) Bilirubin, (B) Bile acids, (C) Alkaline phosphatase, (D) Bile salts
Answer is D. Intrahepatic cholestasis and pruritus gravidarum Results from retained bile salts. Linked to high circulating levels of estrogen, which inhibit intraductal transpo of bile acids. Rx - Ursodeoxycholic acid