Excess secretion of aldosterone causes all except:: (A) Increased ECF, (B) Very High Na+ in plasma, (C) Increased BP, (D) Natriuresis
Answer is B. Ans. (b) Very High Na+ in plasma(Ref: Ganong, 25th ed/p.370)Excess aldosterone causes Sodium and water retentionIn spite of action of aldosterone on the renal tubules, Sodium excretion is increased during aldosterone excess - "Aldosterone Escape phenomenon"This is because of the increase in atrial natriuretic peptide (ANP) secretion that excretes sodium in response to increase in ECF volumeSo, Very High Na+ in plasma is not seen in aldosterone excess