70-year-old female came with multiple erosion & flaccid bulla over skin. Slight rubbing of the skin results in exfoliation of the outermost layer, forming a blister within minutes. Erosions were present over oral mucosa. No target lesion seen. Diagnosis?: (A) Pemphigus vulgaris, (B) Bullous pemphigoid, (C) Dermatitis herpetiformis, (D) SJS
Answer is A. Ans. a. Pemphigus vulgarisMucosal involvement, nikolsky sign (exfoliation of skin on rubbing) positive, flaccid bulla with erosions - all are features of pemphigus vulgaris.Target lesions are seen in erythema multiformeMucosal involvement is absent in bullous pemphogoid.