A relatively newer agent 'latanoprost' is now being used. Which of the following statements is true regarding this agent?: (A) It is PGF2a derivative used in glaucoma, (B) It is selective a1 blocker used in benign hyperophy of prostate, (C) It is a 5a reductase inhibitor used to reduce the size of enlarged prostate gland, (D) It is a PGE2 analogue used intravaginally for cervical priming
Answer is A. -Latanoprost is PGF2 alpha derivative. -It is drug of choice for primary open angle glaucoma. -Heterochromia iridis and hyperichosis are major ocular adverse effects of latanoprost.