True about Dezocine -: (A) Slower acting than morphine, (B) Less potent than morphine, (C) Acts GABA, (D) Doesn't increase histamine release
Answer is D. Ans. is 'd' i.e., Doesn't increase histamine release Dezocine Dezocine is an opioid agonist-antagonist. o Its analgesic potency, onset and duration of action in the relief of postoperative pain are comparable to morphine. o It has no effect on histamine and catecholamines secretion. o Like other agonist-antagonist it exhibits ceiling effect for respiratory depression. It has a high affinity for receptors and moderate affinity for 8 receptors.