Effect of Vmax and Km in competitive inhibition is as follows: (A) Km unchanged, (B) Vmax increased, Km unchanged, (C) Km increased, V max unchanged, (D) Km and Vmax increased
Answer is C. In competitive inhibition, Drug binds to enzyme only .So, Velocity remains unchanged and Conc- km increases. In non- competitive inhibition, drug binds to enzyme substrate complex deceasing velocity unaffecting km. Ref: K.D.Tripati.7th ed. Pg 39