In sickle cell anemia: (A) Glutamate replaces valine, (B) Valine replaces glutamate, (C) Valine replaces aspaate, (D) Aspaate replaces valine
Answer is B. Sickle cell anemia is caused by mutation in the beta globin chain, that changes the amino acid glutamate to valine in the 6th position of beta globin chain of HbRef: Textbook of medical physiology by N Geetha, 3rd edition, page no. 94