Anti-alpha fodrin autoantibodies are seen in: (A) Polymyositis, (B) Crohn's disease, (C) Sjogren's syndrome, (D) Grave's disease
Answer is C. The presence of anti-alpha-fodrin autoantibodies has been repoed to be a highly specific and sensitive test for the diagnosis of Sjogren's syndrome (SjS). Anti-Ro/SSA, and anti-La/SSB autoantibodies are also seen in SjS. In polymyositis antisynthetase antibodies and anti Jo-1 antibodies are seen