Select the best initial treatment for a patient with Behcet syndrome and ocular involvement: (A) Topical glucocoicoids to the oral ulcers and conjunctiva, (B) Thalidomide, (C) Systemic glucocoicoids and azathioprine, (D) Intralesional interferon A
Answer is C. Diagnostic Criteria of Behcet's Syndrome Recurrent oral ulceration Plus 2 of the following: Recurrent genital ulceration Ocular lesions Skin lesions Positive Pathergy test Rx: Condition Treatment Lesion in uveal/ oral cavity Topical Steroids CNS/ocular Systemic steroids Serious cases Thalidomide Recent study Apremilast(Phosphodiesterase-4 inhibitor) Mucocutaneous manifestations ,Ahritis Colchicine