A 15 year old child has developed dystonia and poor school grades. Slit examination is shown below. Which is the initial investigation recommended for the patient ?: (A) Serum ceruloplasmin, (B) Serum copper, (C) 24 hour urinary copper, (D) Liver biopsy
Answer is C. KF Ring can be seen in the image which is seen in Wilson disease Screening test:- 24 hours urinary copper Conformational:- Biopsy. Rx: Trientine- copper chelator Penicillamine- also chelator but less used due to nephrotic side effect. Zinc- is competitive inhibitor of copper in absorption of gut. Zinc acetateisDOCfor Wilson disease.