In TCA cycle, CO2 is released from: (A) Thioinase, (B) Isocitrate dehydrogenase, (C) Citrate dehydrogenase, (D) Alpha ketoglutrate
Answer is D. During the citric acid cycle, two carbon dioxide molecules are removed in the following reactions: A. Step 3, isocitrate (oxalosuccinate) to alpha-ketoglutarate catalyzed by isocitrate dehydrogenase B. Step 4, alpha-ketoglutarate to succinyl CoA.it is from substrate co2is raised..not from enzymes. They are just catalyzing the reaction.Ref: MN Chatterjea Textbook of Medical Biochemistry, 8th Edition, Page no: 219