The cytogenetics of chromophilic renal cell carcinoma is characterized by:: (A) Mutant VHL gene, (B) Loss of 3p, (C) Trisomy 7/17, (D) Loss of 5q 3
Answer is C. Chromophilic renal cell cancer is the other name of papillary renal cell cancer because 80% of chromophilic renal cell cancers show a tubulopapillary architecture. Papillary cancer is associated with trisomy 7, 16, 17.