In tissue, Coccidioides immitis produces: (A) Spherules and endospores, (B) Encapsulated yeast cells, (C) Fine, delicate hyphae, (D) Coarse, septate hyphae
Answer is A. Coccidioides immitis is a dimorphic fungus. Yeast form is a spherule filled with endospores. Mycelial phase contains pseudohyphae, which fragments into ahrospores. Ref: Textbook of Microbiology, Ananthanarayan and Paniker; 9th edition