In all the following metabolic disorders, clinical features are seen due to accumulation of toxic compounds EXCEPT?: (A) Phenylketonuria, (B) Maple syrup urine disease, (C) Urea cycle defects, (D) Mitochondrial disorders
Answer is D. Clinical features are seen due to accumulation of toxic compounds in: Phenylketonuria, Maple syrup urine disease, Urea cycle defects, organic acidurias & porphyrias. Mitochondrial disorders involve defects of energy production or utilisation in various organs of body.