Lesion in Wernicke's encephalopathy occurs in -: (A) Mamillary body, (B) Cerebellum, (C) Motor cortex, (D) Substantia nigra
Answer is A. In thiamine deficiency, hemorrhages into the mamillary bodies cause Wernicke-korsakof syndrome.
Other regions of CNS involved in thiamine deficiency are periventricular regions of the thalamus, the floor of the fourth ventricle and the anterior region of the cerebellum.