Nef gene in HIV is for use-: (A) Enhancing the expression of genes, (B) Enhancing viral replication, (C) Decreasing viral replication, (D) Maturation
Answer is C. nef ( negative factor gene) down regulates viral replication. REF:ANANTHANARAYAN AND PANIKER'S TEXTBOOK OF MICROBIOLOGY 9TH EDITION PAGE NO-572