Among the following 5HT3 antagonist is ?: (A) Cisapride, (B) Ondansetron, (C) Clozapine, (D) Buspirone
Answer is B. Ans. is 'b' i.e., Ondansetron o Stimulation of 5-HT3 receptor is responsible for vomiting induced by anticancer drugs. 5-HT3 receptor antagonists (ondansetron, granisetron and tropisetron) are DOCs for chemotherapy induced vomiting.