True about tetanus is: (A) Gram negative spore forming organism, (B) Produces tetanolysin and tetanospasmin, (C) Trismus and neck stiffness are early signs, (D) Generalized tonic-clonic seizure occurs on hyperstimulation
Answer is B. C.tetani produces two distinct toxins- a hemolysin(tetanolysin) and a powerful neurotoxin9tetanospasmin). These are antigenically and pharmacologically distinct and their production is mutually independent. Ref: Textbook of microbiology; Ananthanarayan and paniker's; 10th Edition; Pg:265