Chronic thiazide therapy causes persistent hypercalcemia due to :: (A) Renal tubular acidosis, (B) Fanconi's syndrome, (C) Hyper vitaminosis D, (D) Hyper parathyroidism
Answer is D. Ans. is 'd' Hyperparathyroidism Chronic thiazide therapy causes hypercalcemia because it enhances the parathyroid mediated increase of Ca reabsorption.Note: Thiazide diuretics cause hypercalcemia where as high ceiling diuretics cause hypocalcemia.Other important side effects of Thiazide diureticsHyperuricemia *Hypokalemia* (More than high ceiling diuretics)Dilutional hyponatremia*Hyperglycemia* and Hyperlipidemia*Magnesium depletion*