In the treatment of congenital adrenal hyperplasia due to lack of 21 b-hydroxylase, the purpose of administration of a synthetic glucocoocoid is:: (A) Inhibition of aldosterone synthesis, (B) Prevention of hypoglycemia, (C) Recovery of normal immune function, (D) Suppression of ACTH secretion
Answer is D. In congenital adrenal hyperplasia, Due to decreased formation of steroids--> decreased feedback inhibition of ACTH. Thus more ACTH is formed which leads to adrenal hyperplasia-->exogenous steroids are given to suppress ACTH secretion.