Which of the following conditions is most likely to lead to a dry tap during bone marrow aspiration-: (A) Acute lymphoblastic leukemia, (B) Multiple myeloma, (C) Megaloblastic anaemia, (D) Idiopathic myelofibrosis
Answer is D. bone marrow aspiration is generally unsuccessful and yields "dry tap" in idiopathic myelofibrosis. Reference textbook of Pathology 7th edition author Harsha Mohan page number 340 see laboratory findings