Which of the following is a quantitative defect in globin synthesis-: (A) Thalassemia, (B) Sickle cell hemoglobinopathy, (C) G6PD deficiency, (D) Diamond-Black fan syndrome
Answer is A. Ans. is 'a' i.e., Thalassemiao Thalassemia is defined as a Quantitative defect in synthesis of structurally normal elobin chains.Sickle Cell Disease represents a qualitative defect in synthesis of globin chains (Structurally abnormal globin chains).# G6PD Deficiency and Diamond-Blackfan Syndrome (Pure Red Cell Aplasia) are not associated with quanitative or qualitative defects in globin chain synthesis