A major source of collagen in cirrhosis -: (A) Kupffer cells, (B) Ito cell (Hepatic stellate cell), (C) Hepatocyte, (D) Canalicular cell
Answer is B. Perisinusoidal stellate cells (Ito cells) play a role in the storage and metabolism of vitamin A and are transformed into collegen producing myofibroblasts when there is inflamation of the liver.
These cells are the major source of collagen in cirrhosis