Which of the following syndromes is best associated with congenital heart disease –: (A) Lesch–Nyhan syndrome, (B) Rasumussen syndrome, (C) Holt Oram syndrome, (D) LEOPARD syndrome
Answer is C. "The strongest familial tendency is known in ASD associated with bony abnormalities (Holt-oram syndrome)"
Genetics of Congenital heart disease