A pregnant woman developed idiopathic cholestatic jaundice. The following condition is not associated:: (A) Intense itching, (B) SGOT, SGPT less than 60 IU, (C) Serum bilirubin > 5mg/dl, (D) Markedly |ed levels of alkaline phosphatase
Answer is C. Intrahepatic Cholestasis of Pregnancy Onset - Third trimester Present with pruritis, icterus or both Lab findings : Sr. bilirubin level <5 mg/dL With minimal or no elevation in transaminases. Alkaline phosophatase levels are elevated. Histopathology: Mild cholestasis with bile plugs in the hepatocytes of the centrilobular regions. Treatment Ursodeoxycholic acid & Cholestyramine acid are used for pruritis