Which of the following is not a feature of chronic leukemia?: (A) Often diagnosed incidentally, (B) Splenomegaly is common, (C) Leucocytosis with circulating blasts and cytopenias are common, (D) Lymphadenopathy is common
Answer is C. Presentation of leukaemia : Acute vs. Chronic Acute leukaemias Sho history of feeling unwell May present with neutropenic fever or bleeding Organ infiltration may occur: skin, gums, testes, meninges Peripheral blood usually shows leucocytosis with circulating blasts and cytopenias Chronic leukaemias Often diagnosed incidentally Usually long history of non-specific symptoms Splenomegaly is common Lymphadenopathy is common in chronic lymphocytic leukaemia Peripheral blood usually shows leucocytosis with circulating mature lymphocytes or myeloid cells; blasts are rare Ref: Leukaemia update. Pa 1: diagnosis and management ; BMJ 2013;346:f1660.