Which of the following contrast is used for esophageal perforation?: (A) Barium swallow, (B) Gadolinium, (C) Lohexol, (D) Gastrograffin
Answer is C. Ref. Grainger and Allison's Diagnostic Radiology. Page. 13
 
Non ionic water soluble contrast should be used in most cases of esophageal perforation such as Iohexol .
Water soluble contrast should be used instead of barium contrast to prevent barium related inflammation of the mediastinum if there is perforation .