The main enzyme responsible for activation of xenobiotics is -: (A) Cytochrome P-450, (B) Glutathione S-transferase, (C) NADPH cytochrome P-450-reductase, (D) Glucuronyl transferase
Answer is A. Most important reaction in biotransformation of xenobiotics is oxidation reaction. The most important enzyme for oxidation reactions is cytochrome P450.