The most impoant determinant of prognosis in Wilm's tumor:: (A) Stage of disease, (B) Loss of heterozygosity of chromosome 1p, (C) Histology, (D) Age less than one year at presentation
Answer is C. Most impoant prognostic factor in most of malignancies- Stage (TNM) Exception- Wilms tumor and soft tissue sarcoma In Wilms tumor, Most impoant Prognostic Factor- Histology > Stage In soft tissue sarcoma, most impoant prognostic factor - Tumor grade