Gleason score: all are true except: (A) Used for grading prostate cancer, (B) Scores range from 1-10, (C) Higher the score, poorer the prognosis, (D) Helps in planning management
Answer is B. The Gleason grading system is used to help evaluate the prognosis of men with prostate cancer using samples from a prostate biopsy. Together with other parameters, it is incorporated into a strategy of prostate cancer staging which predicts prognosis and helps guide therapy. A Gleason score is given to prostate cancer based upon its microscopic appearance. Cancers with a higher Gleason score are more aggressive and have a worse prognosis. Pathological scores range from 1 through 10, with higher the number, indicating greater risks and higher the moality. A total score is calculated based on how cells look under a microscope, with half the score based on the appearance of the most common cell morphology (scored 1--5), and the other half based off the appearance of the second most common cell morphology (scored 1--5). These two numbers are then combined to produce a total score for the cancer.