Is 70 year old man was administered penicillin intravenous within five minutes, he developed generalized uicaria, swelling of lips, hypotension and bronchospasm. the first choice is to administer: (A) Chlorpheneramine inj, (B) Epinephrine inj, (C) High dose hydrocoisone tablet, (D) Nebulized salbutamol
Answer is B. Epinephrine (adrenaline) is a drug of choice for anaphylactic shock. it is given by subcutaneous or intramuscular route in a concentration of 1:1000. intravenous route is rarely used but at match but that much lower concentration(1:10,000) Refer kDT 6/e p128