Drug having narrow therapeutic range is:: (A) Lithium, (B) Seraline, (C) Roboxetine, (D) Dothiepin
Answer is A. Therapeutic range is bounded by the dose which produces a minimal therapeutic effect and the dose which produces maximal acceptable adverse effect Lithium is an unsafe drug with a narrow therapeutic range- 0.6 - 1.2 mmol/L. Ref: KD Tripathi Pharmacology 7th edition (page no;56 )