True about primary sclerosing cholangitis are all except: (A) Commonly affect 40-45 years of age, (B) Jaundice is seen, (C) More common in females, (D) Associated with UC
Answer is C. Clinical features of PSC More common in males, mean age at presentation is 40-45 years About 75 %of patients are asymptomatic at presentation with evidence of cholestatic liver disease such as jaundice, Pruritus and fatigue Symptoms of bacterial cholangitis are uncommon Condition is characterized by relapses & remissions with quiescent periods Median survival from the time of diagnosis ranges from 10 to 12 years Ref: Sabiston 20th edition Pgno :1508-1509