All of the following extraintestinal manifestations of ulcerative colitis respond to colectomy except: (A) Primary sclerosing cholangitis, (B) Pyoderma gangrenosum, (C) Episcleritis, (D) Peripheral ahralgia
Answer is A. .Treatment of Primary sclerosing cholangitis includes * Stenting. * T-tube drainage. * Large dose steroids * Immunosuppression therapy - methotrexate, azathioprine, tacrolimus, cyclosporine. * Ursodeoxycholic acid is beneficial. * Liver transplantation. ref:SRB &;s manual of surgery,ed 3,pg no- 590