Which is the most active single chemotherapeutic agent in the treatment of leiomyosarcoma?: (A) Adriamycin, (B) Daunorubicin, (C) Methotrexate, (D) Cisplatin
Answer is A. Ans. (A) Adriamycin(Ref: KDT 8th/e p926)Doxorubicin (adriamycin) and daunorubicin are anthracycline derivatives.Daunorubicin is mainly used for hematological malignancies (acute leukemia) whereas doxorubicin is used for solid tumors and soft tissue sarcomas.