A patient with clinical features of Glomerulonephritis is having granular staining on immune-fluorescence. All of the following causes have normal C3 except?: (A) IgA Nephropathy, (B) Henoch scholein purpura, (C) Fibrillary GN, (D) Cryoglobulinemia
Answer is D. * Granular pattern on immunofluorescence is seen in immune complex mediated Glomerulonephritis * Cryoglobulinemia leads to low C3 and C4 Immune complex GN Low C3 Normal C3 PSGN MPGN SLE IE Cryoglobulinemia IgA nephropathy HSP Fibrillary and immunotactoid Glomerulonephritis