Baclofen is used in:-: (A) Parkinsonism, (B) Epilepsy, (C) Spasticity, (D) Stroke
Answer is C. GABAB (It is a G protein coupled receptor unlike GABAA, which is an ionotropic receptor) agonists like baclofen increase K+ conductance and can inhibit monosynaptic as well as polysynaptic reflexes. Baclofen is used to relieve spasticity in multiple sclerosis and spinal injuries. It is not useful in cerebral palsy.