Methemoglobinemia can be treated by:: (A) Methylene blue, (B) Vitamin K, (C) Vitamin A, (D) All of the above
Answer is A. Hepatic metabolism of prilocaine generates O-toluidine, which oxidizes hemoglobin to methemoglobin. Methemoglobinemia, if severe, may be treated by the intravenous administration of methylene blue Ref: Miller's anesthesia-7th ed, Chapter 30.