A female developed pain and insect crawling like sensation on legs at night which is relieved by shaking her legs. Which of the following is drug of choice for this condition?: (A) Pramipexole, (B) Gabapentin, (C) Vit B12, (D) Iron tablets
Answer is A. Drug used forRestless legs syndrome(RLS) Thenon-ergot dopaminergic agonistsare the most effective drugs. Relatively low doses:Ropinirole (0.25-1.0 mg)orPramipexole (0.125-0.5 mg)taken 2-3 hours before bed time each day afford dramatic relief in many cases. Other drugs used are benzodiazepines, gabapentin or pregabalin, but these are mostly reserved for non-responsive cases.