Which of the following is neither metabolized by liver nor by kidney: (A) Atracurium, (B) Pancuronium, (C) Vecuronium, (D) Rocuronium
Answer is A. Atracurium * two separate processes for metabolism - Ester Hydrolysis (2/3)-catalyzed by nonspecific esterases - Hofmann Elimination (1/3)-spontaneous nonenzymatic chemical breakdown occurs at physiological pH and temperature