In follicular carcinoma chromosomal translocation is?: (A) PAX8 -PPARrl, (B) RET - PTC, (C) ALK -NMP1, (D) JAK - TEL
Answer is A. Ans. is 'a' i.e., PAX8- PPARrl Various genes involved in thyroid carcinomas arePapillaryo Tyrosine kinase receptors RET or NTRK1o RAS mutationo BRAF oncogeneFollicularo RAS oncogene (NRAS, HRAS and KRAS)o PAX8- PPARrl translocationMedullaryo RETprotooncogne.