Which of the following enzymes is involved in the degradation of the basement membrane?: (A) Metalloproteinases, (B) Oxidases, (C) Elastases, (D) Hydroxylases
Answer is A. Matrix metalloproteinases are a family a proteolytic enzymes that degrade components of the extracellular matrix and basement membrane. Ref: Robbin's Basic Pathology 7th Edition, Page 110, 111, 312, 103; Clinical Gynecologic Endocrinology and Infeility By Marc A. Fritz, Leon Speroff, 2010, Page 596.