The most common cause of Addison's disease is:: (A) Autoimmune adrenalitis, (B) Meningococcal septicemia, (C) Malignancy, (D) Tuberculosis
Answer is A. Primary Chronic Adrenocoical Insufficiency (Addison Disease) Uncommon disorder resulting from progressive destruction of the adrenal coex More than 90% of all cases are attributable to one of four causes: Autoimmune adrenalitis Accounts for 60% to 70% of cases; it is by far the most common cause of primary adrenal insufficiency in developed countries Infections Paicularly tuberculosis and those produced by fungi- histoplasmosis, AIDS Tuberculous adrenalitis, which once accounted for as much as 90% of cases of Addison disease, has become less common with the development of antituberculous agents Genetic conditions - Adrenogenital syndromes Metastatic cancers.