Most impoant investigation for diagnosis of Zollinger Ellison syndrome is: March 2013: (A) Ca2+ infusion test, (B) Secretin injection test, (C) ACTH stimulation test, (D) Steroid assay
Answer is B. Ans. B i.e. Secretin injection test Gastrinoma/ ZES MC site: Duodenum Non beta cell tumour, Neuro-endocrine tumour/ NET secreting: Gastrin Most impoant investigation: Secretin injection test DOC for ZES: Proton pump inhibitors Hepatic metastasis occurs (33%)