Complement responsible for activation of bacterial lysis is:: (A) C3a, (B) C3b, (C) C5-9, (D) C5a
Answer is C. Membrane attack complex is responsible for cell lysis It consist of C-5,6,7,8,9 complement proteins. This MAC get deposited on the cell membrane, and drills holes into it Thus, Cell become premeable to water and ions, leading to osmotic death (lysis)