The pathognomonic feature of classic alpo syndrome is:: (A) Lenticonus and hematuria, (B) Hematuria and sensorineural hearing loss, (C) Sensorineural hearing loss and lenticonus, (D) Hematuria and hyperextensibility of joints
Answer is A. The diagnosis of classic alpo syndrome is based on X-linked inheritance of hematuria, sensorineural hearing loss, and lenticonus. The lenticonus together with hematuria is pathognomonic of classic Alpo syndrome. Reference: Harrisons Principles of Internal Medicine, 18th Edition, Pages 3213-14