Peripheral vasospasm is adverse effect of which drug?: (A) Ropinirole, (B) Levodopa, (C) Bromocriptine, (D) Pramipexole
Answer is C. Bromocriptine and pergolide are ergot derivatives and dopamine agonists These are known to cause vasoconstriction and thus gangrene S/E of Pergolide : Valvular hea disease Pramipexole and ropinirole are also dopamine agonists but these are non-ergot derivatives. These do not cause gangrene and are longer acting. S/E of Ropinirole : Nausea, dizziness, hallucinations,postural hypotension.