All are true regarding tuberous sclerosis except: (A) Autosomal dominant sporadic transmission, (B) Vogt triad of epiloia, (C) Cafe au lait macules exclude the diagnosis, (D) Fibrous facial plaque
Answer is C. C i.e. Cafe au lait macules exclude the diagnosis. Tuberous sclerosis is autosomal dominant disorderQ presenting with classical Vogt's triad of epilepsy, low intelligence/mental retardation/ delayed mile stones and adenoma sebaceum (arjgiofibroma of face)Q and ashleaf (stippled or Confetti) hypomelanotic offwhite macules mostly on trunk & buttockQ. (Acronym-Epiloia)