Which of the following enzymes is the most impoant enzyme for regulating lipogenesis:: (A) Hydratase, (B) Acetyl-CoA carboxylase, (C) Enoyl reductase, (D) Acetyl transacetylase
Answer is B. Acetyl-CoA carboxylase Rate limiting enzyme of fatty acid synthesis. Activated by citrate Inhibited by Palmitoyl CoA. Conves Acetyl CoA to Malonyl CoA, Also uses Biotin as coenzyme and ATP. As ATP is used, name of enzyme is also Malonyl CoA Synthetase.