Which of the following is an oral direct thrombin inhibitor?: (A) Dabigatran, (B) Rivaroxaban, (C) Warfarin, (D) Lepirudin
Answer is A. ORAL: Direct thrombin inhibitor- Dabigatran, Ximelagatran Direct factor Xa inhibitors Apixaban Rivaroxaban Edoxaban Betrixaban Warfarin inhibits Epoxide Reductase thus ?Activated Vit k - ? decreased gamma carboxyglutamate residue ?functionality of factor 2,7,9,10 Lepirudin: - Parenteral Direct Thrombin Inhibitor