Histological appearance of scleroderma include all except: (A) Extensive fibrosis of upper 1/3 of the dermis, (B) Decreased adnexal structure., (C) Homogenization of collagen, (D) Increased dermis thickness
Answer is A. Ans: A Extensive fibrosis of upper 1/3 of the dermis Mucin deposition is a feature of metabolic diseases like pretibial myxedema, scleroderma and lichen myxedematosis. Microscopy appearance of scleroderma- Thinning of epidermis, extensive fibrosis of lower 2/3 of dermis, replacement of subcutaneous fat, homogenization of collagen and decreased adnexal structure.