Superantigen include all, except:: (A) TSST, (B) Exfoliative toxin, (C) Pyrogenic exotoxin, (D) Cholera toxin
Answer is D. Superantigens are certain proteinmolecules that activate very large number of T cells irrespective of antigenic specifities
They bind directly to lateral aspect of TCR β chain and activate upto 20% of the circulating T cells compared to conventional (0.001%) causing multisystem dysfunction.
Examples :
Toxic shock syndrome toxin
Exfoliative toxin
Staphylococcal anterotoxin
Pyrogenic exotoxin