True about toxoplasmosis is all except -: (A) In adults toxoplasmosis is usually asymptomatic, (B) IgG Abs are diagnostic in congenital toxoplasmosis, (C) Definitive host is cat, (D) Encephalitis is rare in immunocompetent individuals
Answer is B. CONGENITAL TOXOPLASMOSIS:.Diagnosis: IgM detection in fetal blood, IgA can also be used (experimental but better sensitivity) and Toxoplasma Ag in amniotic fluid, PCR to detect Toxoplasma genes. TOXOPLASMA GONDII: Three morphological forms: Sporulated oocyst, crescentic tachyzoites, tissue cyst containing bradyzoites Infective form: All three morphological forms are infectious Definitive hosts are cat and other felines Intermediate hosts are man and other mammals (goat, sheep) clinical feature:-In adults toxoplasmosis is usually asymptomatic. Encephalitis is rare in immunocompetent individuals and common in immunocompromised patients