Which of the following is the most common side effect of Cisapride?: (A) Arrythmias, (B) Constipation, (C) Diarrhoea, (D) Convulsion
Answer is C. Cisapride is a prokinetic drug and the most common side effect associated with its use are abdominal cramps, borborygmi and diarrhea. Cisapride is a non selective serotonin 5HT4 agonist and paial 5HT3 agonist, it acts by increasing acetylcholine release from myenteric neurons.