If Two screening tests are used in Series, then there will be: (A) Increased sensitivity and decreased specificity, (B) Increased specificity and decreased sensitivity, (C) Increased sensitivity and increased specificity, (D) Decreased sensitivity and decreased specificity
Answer is B. Screening tests in series: A population is subjected to one screening test followed by a second screening test ; 2nd screening test is applied only in those in which the 1st screening test is positive. - In this, Combined values of Sensitivity decreases Specificity increases PPV increases NPV decreases