Mechanism of action of buspirone is?: (A) 5 HT1A paial agonism., (B) 5 HT1B antagonism., (C) 5 HT1B paial agonism., (D) 5 HT2C antagonism.
Answer is A. Ans. A. HT1A paial agonism5 HT1A:Presynaptic autoreceptor.Modulates serotonin release.Paial 5 HT1A agonists:Buspirone, isapirone, gepirone.Useful as anti-anxiety drug.