Alpha fetoprotein levels are increased in all EXCEPT:: (A) Open neural tube defects, (B) Twin pregnancy, (C) Intrauterine death, (D) Down syndrome
Answer is D. AFP is measured in pregnant women through the analysis of maternal blood or amniotic fluid,
as a screening test for a subset of developmental abnormalities: it is principally increased in open neural tube defects and omphalocele and is decreased in Down syndrome.