The opioid contraindicated in patients on MAO inhibitor is: (A) codeine, (B) Morphine, (C) Fentanyl, (D) Buprenorphine
Answer is C. Some opioid analgesics are associated with a risk of serotonin syndrome in combinations with MAOIs due to their serotonergic propeies. 1. Dextromethorphan, 2. methadone, 3. pethidine, 4. tramadol or 5. fentanyl should be avoided in patients on MAO inhibitor.