The salivary gland neoplasm which characterstically spreads perineurally along the cranial nerves is: (A) Pleomorphic adenoma, (B) Acinic cell carcinoma, (C) Mucoepidermoid carcinoma, (D) Adenoid cystic carcinoma
Answer is D. Perineural involvement is a well-recognized clinicopathologic entity found in head and neck (H&N) cancers, including mucosal epithelial carcinomas and salivary gland malignancies,esp,adenoid cystic carcinoma(31-96%).