Potassium channel openers with anti anginal drug is:: (A) Nicorandil, (B) Dipyridamole, (C) Trimetazidine, (D) Oxyphedrine
Answer is A. (Nicorandil): Ref: 499-KDT (534-KDT 6th)POTASSIUM-CHANNEL-OPENERS* Minoxidil, diazoxide used in hypertension, hyperensive emergencies* Nicorandil, pinacidil, cromakalinNICORANDIL: - This novel antianginal drug activates ATP sensitive K+ channels - hyperpolarizing vascular smooth muscle the vasodilator action is partly antagonized by K+ channel blocker glibenclamide* Dipyridamol, Trimetazidine, oxyphedrine are antianginal drugs