Which of the vitamin deficiency lead to lactic acidosis?: (A) Riboflavin, (B) Thiamin, (C) Niacin, (D) Panthotheic acid
Answer is B. thiamine deficiency in alcoholism may cause impairment of conversion of pyruvate to acetyl-CoA the result is increased plasma concentration of pyruvate and lactate, leading to lactic acidosis ref DM Vasudevan 8th ed page 467