Low serum cobalamin and elevated serum folate levels are seen in?: (A) Acute myeloid leukemia, (B) Celiac sprue, (C) Bacterial overgrowth syndrome, (D) Chronic myeloid leukemia
Answer is C. Low serum cobalamin seen in Blood cancer but depletion of both Vit B12 and folic acid. So, leukemia Ruled out. Celiac Sprue - Involvement of Duodenum>Jejunum>Ileum Folic acid absorption- Jejunum Vit B12 absorption - T. Ileum So, Celiac spure ruled out Bacterial overgrowth syndrome Ileum involvement Vit B12 | Bacteria produce Folate products-Folic acid | IOC: Jejunal Aspirate culture Rx: Antibiotics