Most common oncogene involved in pancreatic adenoma: (A) P53, (B) K-RAS, (C) APC, (D) DCC
Answer is B. 85% of Carcinoma pancreas shows mutant K ras gene on codon 12. 60% show mutation of p53 gene in chromosome 17, over expression of EGFR. Reference : SRB's Manual of Surgery, 6th Edition, page no = 695.