Treatment of choice for genital was in pregnancy is:: (A) Salicylic acid with lactic acid solution, (B) Imiquimod, (C) Podophyllotoxin, (D) Cryotherapy
Answer is D. During pregnancy, electrocoagulation, cryotherapy, or CO2 laser therapy should be administered at approximately 32 weeks to avoid, on one hand, post-treatment necrosis, which may last as long as 4-6 weeks, and to prevent, on the other hand, recurrence if treated too early. Podophyllin, podofilox, and imiquimod should not be used during pregnancy. Also know: Treatment of Condyloma Acuminata: Applied by health care provider Bichloracetic acid or trichloroacetic acid, 50-80% solution Podophyllin 10-25% in tincture of benzoin Cryosurgery, electrosurgery, simple surgical excision, laser vaporization Applied by patient Podofilox 0.5% solution or gel Imiquimod 5% cream (topically active immune enhancer that stimulates production of interferon and other cytokines) Ref: Bornstein J. (2013). Chapter 39. Benign Disorders of the Vulva & Vagina. In A.H. DeCherney, L. Nathan, N. Laufer, A.S. Roman (Eds), CURRENT Diagnosis & Treatment: Obstetrics & Gynecology, 11e.