Which of the following is the most preferred approach for pituitary surgery at the present time?: (A) Transcranial, (B) Transcallosal, (C) Transethmoidal, (D) Transsphenoidal
Answer is D. Transsphenoidal approach through the nose is the most preferred approach for pituitary surgeries. Craniotomy is needed for resection of large tumors. Ref: Bailey and Love Sho Practice of Surgery, 25th Edition, Page 634.