Which of the following is false about alkaptonuria?: (A) Genitourinary system not involved, (B) Homogentisic acid oxidase deficiency, (C) Black urine, (D) Calcification in vertebral bodies
Answer is A. a. Genitourinary system not involved(Ref: Nelson's 20/e p 636-642, Ghai 8/e p 653-655)Genitourinary system is also involved in Alkaptonuria, as this enzyme is expressed only in liver and kidneys; darkening of urine on standing is an important feature of Alkaptonuria.