Auto immunity in EBV infection is the result of: (A) Molecular mimicry, (B) PolyclonalB cell activation, (C) Expressing sequestered antigen, (D) Antigenic cross reactivity
Answer is B. Ref Robbins 8/e p212; 9/e p216 Infection with Epstein-Barr virus (EBV), the cause of infectious mononucleosis, has been associated with subsequent development of systemic lupus erythematosus and other chronic autoimmune illnesses It is due to PolyclonalB B cell proliferation and activation