Which component of Strep. Pyogenes has cross reactivity to Synovium of Human tissues?: (A) Capsular Hyaluronic Acid, (B) Cell wall protein, (C) Group A carbohydrate Antigen, (D) Peptidoglycan
Answer is A. Capsular Hyaluronic acid from streptococcus pyogenes always cross-reacts with human synol fluid and not with cell wall protein, group A carbohydrate antigen and peptidoglycan. Ref: Textbook of Microbiology By Ananthanarayan, 7th Edition, Pages 205, 207; Lippincott's Illustrated Reviews: Pharmacology, 2nd Edition, Pages 80, 81