Toxicity of cycloserine is enhanced by-: (A) Toxicity of cycloserine is enhanced by-, (B) Amphotericine-B, (C) Simvastatin, (D) Alcohol
Answer is D. Ans. is 'd' i.e., Alcohol o Reactions to cycloserine most commonly involve the CNS Somnolence, headache, tremor, dysahria, veigo, confusion, nervousness, irritability, psychotic state, suicidal tendencies, paranoid reactions, ankle clonus, hyperreflexia, visual disturbances, seizures. o Large doses of cycloserine or the concomitant ingestion of alcohol increases the risk of seizures. o Cycloserine acts by inhibiting cell wall synthesis.