Which enzyme metabolizes succinylcholine?: (A) Acetyl cholinesterase, (B) Butyryl cholinesterase, (C) Tissue esterase, (D) Nonspecific esterase
Answer is B. Liver produces an enzyme called Butyrylcholinesterase and release in plasma called plasma cholinesterase or Pseudocholinesterase. Succinylcholine is metabolized by butyrylcholinesterase/plasmacholinesterase/pseudocholinesterase. drugs metabolized by pseudocholinesterase 1. succinylcholine 2. Mivacurium 3. ester local anaesthetics