What is function of Intrinsic Factor?: (A) Increases cobalamin absorption, (B) Increases folate absorption, (C) Conves prothrombin to thrombin, (D) Conve s fibrinogen to fibrin
Answer is A. Vit B12 synonyms are cobalamine, extrinsic factor of castle, anti-pernicious anaemia factor parietal cells of the stomach secrete a special protein called intrinsic factor (IF). IF is required for the absorption of Vit B12 one molecule of IF can combine with 2 molecules of B12 this complex attaches to specific receptors on mucosal cells and get internalised ref DM Vasudevan 8thed page 477