MOA of oral hypoglycemic agent: (A) Inhibit glucose uptake by skeletal muscle, (B) Enhance glucose uptake by skeletal muscle, (C) Stimulate glycogenolysis, (D) Stimulate gluconeogenesis
Answer is B. Ans. (b) Enhance glucose uptake by skeletal muscleRef.: KDT 6th ed. / 267OHA DrugsMechanism of actionMetformin and thiazolidinedi- ones* Inhibition of hepatic gluconeogenesis* Enhance glucose uptake in skeletal muscleSulfonylureas and ripaglindeStimulate insulin release from pancreasAcarboseDecrease absorption of glucose from intestine