Aspirin is used for secondary prevention of ischemic hea disease because it:-: (A) Inhibits TXA2 synthesis by platelets, (B) Inhibit prostacyclin synthesis, (C) Inhibits release of EDRF, (D) Inhibit synthesis of endothelins
Answer is A. Aggregatory substances: TXA2 ADP Inhibits aggregation: PGI2. Aspirin is Irreversible inhibitor of COX - thus preventing TXA2 formation & aggregation of PLATELETS.