Which of the following statement is true regarding opening snap?: (A) It is a high-pitched diastolic sound, (B) It is due to opening of stenosed aoic valve, (C) It indicates pulmonary aerial hypeension, (D) It precedes the aoic component of second hea sound
Answer is A. The high-pitched opening snap (OS) of MS occurs after a very sho interval after the second hea sound. The A2-OS interval is inversely propoional to the height of the left atrial-left ventricular diastolic pressure gradient. The intensity of both S1 and the OS of MS decreases with progressive calcification and rigidity of the anterior mitral leaflets.Ref: Harrison; 19th edition; Page no: 1447