Inhibits mitosis by forming microtubules -: (A) Vinca alkaloids, (B) Docetaxel, (C) Etoposide, (D) Colchicine
Answer is B. Ans. is 'b' i.e., Docetaxel Taxanes (Paclitaxel and Docetaxel) enhances polymerization of tubulin (a mechanism opposite to that of vinca alkaloids) --> the microtubules are stabilized and their depolymerization is prevented. Vinca alkaloids (vincristine, vinblastine) prevent polymerization and assembly of microtubules.