Esmolol is a sho acting b blocker because: (A) It has more plasma protein binding, (B) Its plasma hydrolysis by esterases is rapid, (C) It has high lipid solubility, (D) It has high oral bioavailability
Answer is B. * Esmolol - Shoest acting b blocker * Nadolol - Longest acting b blocker * Esmolol is metabolized by pseudocholinesterase hence it is sho acting. * Drugs metabolized by pseudocholinesterase SUCCINYLCHOLINE ESMOLOL REMIFENTANIL