Which statement is false regarding familial adenomatous polyposis :: (A) Males are usually carriers, (B) Autosomal dominant inheritance, (C) If not treated progress to malignancy in 100% of cases, (D) Males and females are affected equally.
Answer is A. Ans. is 'a' i.e. males are usually carriers Familiar polyposis coli is an autosomal dominant* condition affecting males and females equally.It is characterized by presence of thousands of adenomatous polyps throughout the large bowel.Carcinomatous change* supervenes in these polyps in 100% of cases by the age of 30-35yrs.Therefore prophylactic colectomy is done. *