The class of antibodies that plays an important role in type I hypersensitivity reactions is _____.: (A) IgA, (B) IgD, (C) IgE, (D) IgG
Answer is C. Although IgE is the least prevalent immunoglobulin in the body, it is the major antibody mediator of type I hypersensitivity reactions. These reactions are caused primarily by prior sensitization and the accumulation of IgE to a specific allergen.