1722. A patient presents with macroglossia and atrophy of tongue papilla. His Hb Is 11.5 and MCV is 100. What should be the next step in Investigating this patient ?: (A) B12 estimation, (B) Brush biopsy of the lesion, (C) Fluconazole treatment, (D) Incision biopsy
Answer is A. <p>Deficiency of vit B12 & folate presents with anemia(macrocytic megaloblastic anemia), glossitis(smooth,beefy,red tongue).Hb level will be below normal range & MCV wil be elevated.So this is a case of vit B 12 deficiency & next choice of investigation is serum Vit B12 assay. </p><p>Harsh mohan textbook of pathology sixth edition pg no 306</p>