Among patients with polymyositis, which one of the following auto-antibodies is associated with an increased risk of interstitial lung disease?: (A) Anti-CCP antibody, (B) Anti ds DNA antibody, (C) Anti cardiolipin antibody, (D) Anti-Jo-1 antibody
Answer is D. Myositis Specific Antibodies Anti Jo-1 and anti synthetase antibodies Polymyositis and dermatomyositis with Interstitial lung disease, ahritis, mechanic's hands Anti-Mi-2 Dermatomyositis with rash Anti MDAS Dermatomyositis with rapidly progressive lung disease Anti-10 Juvenile dermatomyositis Anti-Signal recognition paicle Severe acute necrotizing myopathy