JAK/STAT signalling cascade is employed by:: (A) Growth hormone, (B) Thyroid hormone, (C) Insulin, (D) Glucocoicoids
Answer is A. Growth hormone receptor is a transmembrane receptor which is associated with JAK-STAT pathway signalling. Other hormone which has JAK-STAT signalling is prolactin Hormone which also acts transmembrane receptor which has intrinsic tyrosine kinase activity- Insulin, growth factors.