Wernicke's encephalopathy occurs due to deficiency of: (A) Vitamin B1, (B) Vitamin B2, (C) Vitamin B6, (D) Vitamin B12
Answer is A. (A) Vitamin B1 # Dry Beriberi involves both the peripheral and the central nervous systems.> Peripheral nerve involvement is typically asymmetric motor & sensory neuropathy with pain, paresthesias& loss of reflexes.> The legs are affected more than the arms. Central nervous system involvement results in Wernicke-Korsakoff syndrome.> Wernicke's encephalopathy consists of nystagmus progressing to ophthalmoplegia, truncal ataxia & confusion> Koraskoff's syndrome includes amnesia, confabulation, and impaired learning.