Loss of foot processes seen on electron microscopy of renal biopsy is a classical feature in which of the following?: (A) Membranous nephropathy, (B) Minimal change disease, (C) lgA nephropathy, (D) Rapidly progressive gloerulonephritis
Answer is B. IgA nephropathy - Mesangial IgA deposits RPGN - Findings depend on the type of RPGN and cause. Membranous nephropathy - Subepithelial deposits (Spike and dome appearance) Minimal change disease (MCD): Effacement of foot processes of podocytes and damage to podocytes seen on electron microscopy Most common cause of nephrotic syndrome in children is MCD and in adults, it is FSGS.