Gene responsible for Anterior segment morphogenesis: (A) PAX 6, (B) PIT X 2, (C) TSG, (D) GLC 1
Answer is A. GENETICS IN CORNEA * PAX 6 gene a/w- Ectodermal Ectodactyly dysplasia & eye morphogenesis *PITX2 gene- Axenfeld Riger Syndrome Corneal Dystrophy & Anomalies *Lattice & Granular Corneal Dystrophy- TGF B1, 5q31, AD *Macular - AR, 16q22 *Fuch's endothelial dystrophy: AD, COL8A2 *Megalocornea: XLR, mostly males are involved Extra edge: - Faulty migration of NCC causes anterior segment dysgenesis.