Enzyme deficiency in Natowicz syndrome is: (A) Iduronate sulfatase, (B) Hyaluronidase, (C) b-Glucuronidase, (D) Galactosamine 6-sulfatase
Answer is B. Disease name Abbretion Enzyme Defective GaG(s) affected Symptoms Natowicz syndrome MPS IX Hyaluronidase Hyaluronic acid Joint pain, sho stature Reference: Harper; 30th edition; Page no:639; Table: 50-8