Perivascular lymphocytic and microglial nodules are seen in: (A) Multiple sclerosis, (B) HIV encephalitis, (C) Bacterial meningitis, (D) CMV encephalitis
Answer is B. HIV encephalitis Chronic inflammatory reaction characterized by widely distributed microglial nodules, often containing macrophage-derived multinucleated giant cells; foci of tissue necrosis . Reactive gliosis are sometimes seen together with these lesions. Microglial nodules found near small blood vessels, show abnormally prominent endothelial cells and perivascular foamy or pigment-laden macrophages.