Which of the following is used for the prevention of Pneumocystis jiroveci infection in HIV positive patients?: (A) Azithromycin, (B) Acyclovir, (C) Levofloxacin, (D) Sulfamethoxazole + trimethoprim
Answer is D. Prophylaxis with trimethoprim-sulfamethoxazole (TMP-SMZ) prevents- infection with P.Jiroveci, Toxoplasma gondii. Intolerance of TMP-SMZ is common Alternative agents provide less adequate protection against Pneumocystis species.