Features of epidermolysis bullosa –: (A) ↓ Adhesion fibrils, (B) Present as miliary & scaring, (C) IgG deposits in epidermo-dermal junction, (D) None of the above
Answer is A. Epidermolysis bullosa is a group of inherited bullous disorder. Epidermolysis bullosa is due to defect in anchoring complex (keratin - containing intermediate filaments and collegen type VII) that attaches basement membrane to epidermal hemidesmosomes (by keratin containing intermediate filament) and to dermis (by collegen type VII).