The secretion of which of the following hormones increases with chlorpromazine therapy?: (A) Prolactin, (B) Gonadotropin, (C) Coicotropin, (D) Antidiuretic hormone
Answer is A. (Ref: KDT 6/e p431) Dopamine acts like prolactin releasing inhibitory hormone. D2 blockers decrease the action of dopamine and can result in hyperprolactinemia. Some drugs blocking D2 receptors are: Antipsychotics like chlorpromazine Metoclopramide