Isoniazide is metabolized by ?: (A) Acetylation, (B) Oxidation, (C) Reduction, (D) Hydrolysis
Answer is A. Ans. is 'a' i.e., Acetylation Isoniazid is extensively metabolized in liver most impoant pathway being N - acetylation by NAT The acetylated metabolite is excreted in urine. Drugs metabolized by acetylation Sulfonamides (including dapson) Procainamide PAS INH Hydralazine