Agonist is having: (A) Affinity with intrinsic activity 0, (B) Affinity with intrinsic activity 1, (C) Affinity with intrinsic activity -1, (D) None
Answer is A. Ref-KDT 6/e p41 Agonist have intrinsic acriacti 1 because Intrinsic activity is a measure of the ability of a drug that is bound to the receptor to generate an activating stimulus and produce a change in cellular activity. Both agonists and antagonists can bind to a receptor. However, only agonist molecules can activate the receptor.