A 22 year old presents to his physician with hemoptysis and hematuria with basement membrane antibodies. Most likely diagnosis is:: (A) Wagner's Granulomatosis, (B) Goodpasture's syndrome, (C) PAN, (D) Churg-Strauss syndrome
Answer is B. Answer is B (Goodpasture's Syndrome) Goodpasture's Syndrome is an autoimmune disease characterized by formation of Anti-Glomerular Basement Membrane Antibodies (Anti-GBM Antibodies) that attack both, Pulmonary Capillaries (Hemoptysis) and the Glomerulus (Hematuria) The association of Hemoptysis and Hematuria along with anti-basement membrane antibodies suggests a diagnosis of Goodpasture's Syndrome