Which of the following is a calcineurin inhibitor?: (A) Cyclosporine, (B) Methotrexate, (C) Azathioprine, (D) Mycophenolate mofetil
Answer is A. Ans. (A) Cyclosporine(Ref: Goodman Gilman 12th/e p1008; Katzung 12th/e p986; KDT 8/e p937)Cyclosporine and tacrolimus act as immunosuppresants by their inhibitory action on calcineurin.