Features of multiple myeloma are: (A) B cell monoclonal proliferation, (B) B cell in bone marrow, (C) B cell in peripheral blood, (D) Plasma cell secretes immunoglobulin
Answer is A. Multiple myeloma is a malignant proliferation of plasma cells. Normal plasma cells are derived from B cells & prodece immunoglobulins which contain heavy & light chains. Normal immunoglobulins are polyclonal,which means that a variety of heavy chains are produced . In myelona,plasma cells produce immunoglobulin of a single hwavy & light chain , a monoclonal protein commonly referred to as a paraprotein.Reference :Davidson's principles &practice of medicine 22nd edition pg no 1046.