All of the following are intermediates of TCA cycle, except :: (A) Malonate, (B) alpha -ketoglutarate, (C) Succinate, (D) Fumarate
Answer is A. Ans. a) Malonate is not an intermediate of TCA cycle Malonate Malate competitive inhibitor of succinate dehydrogenase intermediate in TCA cycle. TCA cycle intermediates are Citrate, Isocitrate, a-ketoglutarate, succinyl-CoA, Succinate, Fumarate, Malate, oxaloacetate. Acetyl-CoA is completely oxidised Oxaloacetate is regenerated.