A mother presents to the neonatology OPD with her baby because of yellow extremities. On examination, there is petechial rash over the body, hepatosplenomagaly, microcephaly. What is the causative organism?: (A) CMV, (B) Rubella, (C) HSV, (D) Varicella
Answer is A. Features of congenital CMV infection are: petechial rash, jaundice, hepatosplenomegaly, microcephaly, periventricular calcification, deafness, chorioretinitis,IUGR. congenital rubella syndrome: triad of cardiac defects, cataract and conductive hearing loss neonatal herpes presents as skin lesions with eye involvement, encephalitis, disseminated disease. fetal varicella syndrome: cicatrizing/ scarring skin lesions, chorioretenitis, hypoplastic limbs, LBW, CNS defects- due to cerebral atrophy. Reference: Ananthanarayan and Paniker&;s Textbook of Microbiology Tenth edition