In the apoptosis,Apaf-1 is activated by release of which of the following substances from the mitochondria: (A) Bcl-2, (B) Bax, (C) Bcl-XL, (D) Cytochrome c
Answer is D. Ref, Harrison 17/e p506,9/ep55 Apoptosis or programmed cell death can be induced by intrinsic or extrinsic pathway.as can be seen in the intrinsic pathway;cytc gets associatio with ApAF-1 which activates caspases and causes cell death