In chronic renal failure, there is?: (A) Decrease anion gap, (B) Normal anion gap, (C) Increased anion gap, (D) Metabolic alkalosis
Answer is C. Chronic renal failure leads to increase anion gap Causes of the increased anion (>12 mEq/L): Milk-alkali syndrome Uremia Diabetic ketoacidosis Propylene glycol Isoniazid intoxication Lactic acidosis Ethanol ethylene glycol Rhabdomyolysis/renal failure Salicylates