Serum Creatine PhosphoKinase-3 (CPK-3) is elevated in-: (A) Muscular dystrophy, (B) Myocardial infarction, (C) Alcoholic cirrhosis, (D) Brain tumours
Answer is A. Musculardystrophy CreatineKinase(CK)or CreatinePhosphokinase(CPK)catalysestheinterconversionof phosphocreatineto creatine. CPKexistsasthreeisoenzymes.Eachisoenzymeisa dimercomposedoftwosubunits- M(muscle)orB (Brain)orboth Isoenzyme SubUnit Tissueoforigin CPK1 BB Brain CPK2 MB Hea CPK3 MM SkeletalMuscle