Best site for taking biopsy for viral esophagitis is: (A) Edge of ulcer, (B) Base of ulcer, (C) Adjacent induratrd area around ulcer, (D) Surrounding normal mucosa
Answer is B. Refer Robbins page no 768 Herpes virus typically cause punched out ulcers the nuclear inclusions of herpes virus arr found in a narrow rim of degenerating epithelial cells at the margin of ulcer For biopsy should be taken from edge of ulcer in HSV and base of ulcer in CMV