Botulinum toxin acts by which mechanism: (A) Transmitter uptake inhibition, (B) Transmitter release inhibition, (C) Transmitter synthesis inhibition, (D) Transmitter breakdown inhibition
Answer is B. Clostridium botulinum produces type A toxin. It acts by blocking the release of acetylcholine at the synapses and neuromuscular junction. Thus blocks neuromuscular transmission. Reference: Textbook of Microbiology; Anathanarayan and paniker's; 10th edition; Page no: 269