First change observed in distal part, of a cut nerve is: (A) Axonal degeneration, (B) Sprouting, (C) Myelin degeneration, (D) Schwann cells proliferation
Answer is A. Ans. (a) Axonal degeneration(Ref: Ganong, 25th ed/p.89)Axonal degeneration is the earliest to occur followed by degeneration of myelin sheathMacrophages and Schwann cell clear the debris following degenerationThe neurolemma of the nerve fiber doesn't degenerate and remains as a hollow tube