Mechanism of action of pralidoxime is:: (A) Stimulation of ACh receptors, (B) Inhibition of breakdown of ACh, (C) Blockade of ACh receptors, (D) Reactivation of AChE enzyme
Answer is D. Ans. (D) Reactivation of AChE enzyme(Ref: Katzung 10/e p116; KDT 8th/e p123)Pralidoxime and diacetylmonoxime are cholinesterase regenerator compounds used for organophosphate poisoning.