All are true regarding pseudomembranous colitis, except: (A) It is caused by clostridium difficile, (B) The organism is a normal commensal of gut, (C) It is due to production of phospholipase A, (D) It is treated by vancomycin
Answer is C. Clostridium difficile causes acute colitis with bloody diarrhea and pseudomembranous colitis. A common cause of nosocomial diarrhea. The disease follows the use of broad-spectrum antibiotics to which it is resistant. Exotoxin A and B involved in the pathogenesis. It is not a normal commensal, it is an oppounistic organism. Reference: Textbook of Microbiology; Anathanarayan and paniker's; 10th edition; Page no: 270