A 8 year old male had non blanching rashes over the shin and swelling of knee joint with haematuria and protein +. Microscopic analysis of his renal biopsy specimen is most likely to show ?: (A) Tubular necrosis, (B) Visceral podocyte fusion, (C) Mesangial deposits of TgA, (D) Basement membrane thickening
Answer is C. Ans. is 'c' i.e., Mesangial deposits of IgA o This child has --> i) Rash ii) Ahritis (swelling of knee joint) iii) Haematuria o All these suggest the diagnosis of Henoch Schonlein purpura o HSP is characterized by deposition of IgA in the mesangium.