Antihistamines used in motion sickness is: (A) Cetrizine, (B) Meclizine, (C) Diphenhydramine, (D) Fexofenadine
Answer is C. Diphenhydramine and promethazine have maximum anti cholinergic activity and maximum ability to cross the blood brain barrier and are thus most effective in motion sickness . Refer katzung 11/e p278