Which of the following is a radioprotector?: (A) Colony stimulating factor, (B) Amifostine, (C) Cisplatin, (D) Methotrexate
Answer is B. AMIFOSTINE: It is an organic thiophosphate which on activation by alkaline phosphatase acts as a cytoprotective against cancer chemotherapy and radiotherapy.It is paicularly used for prophylaxis of cisplatin induced neuro/nephrotoxicity and radiotherapy related xerostomia. ESSENTIALS OF MEDICAL PHARMACOLOGY K.D.TRIPATHI SEVENTH EDITION PAGE NO:876