A major lipid of mitochondrial membrane is: (A) Lecithin, (B) Inositol, (C) Plasmalogen, (D) Cardiolipin
Answer is D. Inner mitochondrial membrane: The inner mitochondrial membrane is very rich in proteins and the ratio of lipid to proteins is only 0.27:1 by weight. It contains high propoion of the phospholipid cardiolipin. In contrast to outer membrane, the inner membrane is viually impermeable to polar and ionic substances. These substances enter the mitochondrion only through the mediation of specific transpo proteins.Ref: MN Chatterjea Textbook of Medical Biochemistry, 8th edition, page no: 6