Management of steroid resistant asthma is done by: March 2005: (A) Oral steroids, (B) Long acting Beta-2 agonist, (C) Leucotrine antagonist, (D) Theophylline
Answer is A. Ans. A: Oral steroids It is defined as failure to respond to a high dose of oral prednisolone (40 mg once daily over 2 weeks) More common is reduced responsiveness to coicosteroids where control of asthma requires oral coicosteroids (coicosteroid dependent asthma) Most of these patients requires a maintenance therapy with oral coicosteroids. Low dose of theophylline may be helpful in some patients. Few patients may benefit from infusion of beta-2 agonists.