Vitamin B1 is required for which reaction: (A) Transamination, (B) Oxidative decarboxylation, (C) Carboxylation, (D) All of the above
Answer is B. Ans. is 'b' i.e.,Oxidative decarboxylation Active form (coenzyme form) of thiamine is thiamine pyrophosphate (TPP), also called thiamine diphosphate (TDP).TPP acts as coenzyme forOxidative decarboxylation:- Pyruvate dehydrogenase, a-ketoglutarate dehydrogenase, brached-chain keto acid dehydrogenase.Transketolase in PPP.