Digeorge syndrome is due to defect of?: (A) pouch 1, (B) pouch 2, (C) pouch 3 and 4, (D) pouch 5
Answer is C. Digeorge syndrome is due to defect of pouch 3 and 4. Pouch 3 compromised - No thymus - CMI decreases - Severe bacterial infections Pouch 3 & 4 compromised - absent or poorly developed parathyroid - low PTH - Hypocalcemia.