Which of the following immunosuppressant drugs is nephrotoxic?: (A) Azathioprine, (B) Cyclophosphamide, (C) Mycophenolate mofetil, (D) Tacrolimus
Answer is D. Tacrolimus and cyclosporine toxicity include nephrotoxicity, neurotoxicity, hyperglycemia, hypertension, hyper­kalemia and GI complaints. Cyclosporine also cause hirsutism, which is not seen with tacrolimus use.