Eosinophilia in necrosed tissue is due to: (A) Coagulation of proteins, (B) Denaturation of enzymes, (C) Denaturation of protein, (D) Mitochondrial damage
Answer is C. Ans. is 'c' i.e., Denaturation of protein Necrotic cells show increased eosinophilia in hematoxylin and eosin (H & E) stains. It is due to - Loss of cytoplasmic RNA (or ribonucleoprotein/RNP) which binds the blue dye, hematoxylin. Denatured cytoplasmic proteins which bind the red dye, eosin.