Which of the following is an example of proliferation signal inhibitor?: (A) Tacrolimus, (B) Sirolimus, (C) Cyclosporine, (D) None of the above
Answer is B. A new class of immunosuppressive agents called proliferation-signal inhibitors (PSIs) includes sirolimus (rapamycin) and its derivative everolimus. Ref: Katzung 11th edition Chapter 51.