A 40-years-old non-diabetic woman patient is bought to the emergency depament, by paramedics with hypoglycemia. The paramedics suspect a,& insulin overdose, you suspect Insulinoma. The lab result that would confirm your suspicion of Insulinoma is: (A) Insulin level > C-peptide level, (B) Insulin level < C peptide level, (C) Insulin level = C-peptide level, (D) Insulin antibody level = insulin level
Answer is C. InsulinomasWhipple's triadDiagnostic testsFasting hypoglycemia+Symptoms of hypoglycemia+Immediate recovery after IV glucose along with increased insulin & C peptide levels and absent insulin antibodiesSuppression of insulin secretion by fasting Measurement of proinsulin to insulin by RIA C peptide levels Glucagon test Tumour localization by CT, MRI &radio nuclear scan (Refer: Harrison's Principles of Internal Medicine, 18th edition, pg no: 3066-3067)