Vitamin D is synthesized by?: (A) Keratinocytes, (B) Granular cells, (C) Melanocytes, (D) Prickle cells
Answer is A. The keratinocytes of the skin are unique in being not only the primary source of vitamin D for the body, but in possessing the enzymatic machinery to metabolize vitamin D to its active metabolite 1,25 dihydroxy vitamin D. Fuhermore, these cells also express the vitamin D receptor (VDR) that enables them to respond to the 1,25(OH)2D they produce.