True about respiratory distress syndrome is all except:: (A) Damage to type I/II pneumocyte, (B) Histological feature is diffuse alveolar damage, (C) Formation of hyaline membrane in this condition, (D) Excellent response to oxygen therapy
Answer is D. In adult respiratory distress syndrome, there is damage to type-I / II pneumocytes as well as formation of hyaline membrane due to endothelial cell damage which increases vessel permeability - formation of membrane with fibrinogen-Hyaline appearance. Histological feature is diffuse alveolar damage. In such condition, oxygen given to patient cannot diffuse along the epithelial wall, so there is poor response to oxygen therapy.