The non depolarizing neuromuscular blocker has a normal activity with all the following except:: (A) Myotonia, (B) Muscular dystrophy, (C) Upper motor neuron lesions, (D) Myasthenia gravis
Answer is D. In myasthenia gravis circulating antibodies produce a functional reduction in the number of postsynaptic acetylcholine receptors. The myasthenia patients are usually resistant to Succinylcholine. Sensitively to non depolarizing NMB is increased to a variable extent. In Myasthenia patient nondepolarizing neuromuscular is given is less dose.