The antibody responsible for heparin induced thrombocytopenia is:: (A) Antiheparin / PF4 antibody, (B) Antiheparin / PF2 antibody, (C) Antiheparin / GP IIb/IIIa antibody, (D) Antiheparin GP Ib/IX antibody
Answer is A. HIT results from antibody formation to a complex of the platelet specific protein platelet factor 4 and heparin. Ref: Harrisons principles of internal medicine, Edition -18, Page - 967.