In contact dermatitis which cells play major role-: (A) T-cells, (B) B-cells, (C) Langhan cells, (D) Macrophage
Answer is A. Contact dermatitis is a type IV hypersensitivity reaction. - this is a cell mediated response. The antigen activates specifically sensitised CD4 & CD8 T lymphocytes leading to the secretion of lymphokines and phagocyte accumulation. Reference : Anathanarayan & paniker's 9th edition, pg no: 162 <\p>