Which antiepileptic drug leads to gingival hyperplasia:: (A) Phenytoin, (B) Carbamazepine, (C) Valproate, (D) Lamotrigine
Answer is A. Ans. A. PhenytoinPhenytoin causes gingival hyperplasia, hirsutism, megaloblastic anemia, osteomalacia. Carbamazepine causes agranulocytosis, valproate is hepatotoxic and also causes spina bifida. Lamotrigine is known to cause Steven Johnson syndrome.