Most impoant mediator of chemotaxis is: (A) C3b, (B) C5a, (C) C5_7, (D) C2
Answer is B. ref Robbins 7/e p56 ,9/e p77 C5a is a strong chemoattractant and is involved in the recruitment of inflammatory cells such as neutrophils, eosinophils, monocytes, and T lymphocytes, in activation of phagocytic cells and release of granule-based enzymes and generation of oxidants, all of which may contribute to innate immune functions or tissue ...