True regarding transport across a cell membrane is: (A) Cl- with glucose symport, (B) Na+ with glucose antiport, (C) Na+ with glucose symport, (D) K+ with glucose symport
Answer is C. Ans. (c) Na+ with glucose symportSodium Glucose Cotransporter (SGLT) is an example for a secondary active transport processLocations - SGLT 1-intestine, SGLT 2-Proximal convoluted tubule of kidneyInhibitors of SGLT-2 are synthetic analogs of phlorizin namely canagliflozin, dapagliflozin, and empagliflozinThese drugs are used in treatment of diabetes mellitus