ANCA negative vasculitis amongst the following is: (A) Wegner granulomatosis, (B) Churg strauss syndrome, (C) Polyaeritis nodosa, (D) Microscopic polyangiitis
Answer is C. ANCA p-ANCA | MPO ANCA Churg strauss syndrome Microscopic polyangiitis c-ANCA | PR3 ANCA Wegener granulomatosis Polyaeritis nodosa: ANCA negative medium vessel vasculitis Deposition of Immune complex: Fibrinoid necrosis (Type 3 HSR) 30% of patient have history of Hep B infection HBsAg + anti-HBs ab. (complex). | Deposition in many organ Sparing of small vessel (LUNGS)