Murphy's sign is seen in: (A) Acute cholecystitis, (B) Cholangiocarcinoma, (C) Cholangitis, (D) Periampullary cancer
Answer is A. In the acute cholecystitis, the patient may have right upper quadrant tenderness that is exacerbated during inspiration by the examiner's right subcostal palpation (Murphy's sign). A positive Murphy's sign suggests acute inflammation and may be associated with a leukocytosis and moderately elevated liver function tests.Ref: Bailey and love 27e pg: 1199