Intrinsic factor is required for absorption of -: (A) Folic acid, (B) Vitamin B12, (C) Vitamin B2, (D) Vitamin B6
Answer is B. Ans. is 'b' i.e., Vitamin B12 o Vitamin B12 (cyanocobalamine) is absorbed in the ileum, o Intrinsic factor (of castle) is necessary for its absorption. o IF is secreted by oxyntic cells of stomach. In the lumen of the small intestine, IF forms a complex with vitamin B12. o Vitamin B12-IF complex binds with a specific receptor on the surface of the epithelial cells of the ileum. o Vitamin B12 is transported into the enterocytes leaving behing IF at the brush border.