Regarding transmission of HIV to infant from infected HIV mother, which statement is/are true:: (A) Sta zidovudine during labour, (B) 25% chance of veical transmission, (C) Avoid breastfeeding, (D) Vaccinate infant with OPV and MMR
Answer is A. Zidovudine is given IV Infusion staing at onset of labour or4 hours prior to CSsection,Loading dose is 2mg/kg/hr and maintainance dose is 1mg/kg/hr Transplacental transmission occurs :20% before 36 weeks,50% before delivery,30% during labour Breast feeding doubles risk of MTCT but alternative forms of infant nutrition are not safe. D.C.DUTTA'S TEXTBOOK OF OBSTETRICS,Pg no:283,9th edition