Vitamin required for the activity of transaminases is:: (A) Folic acid, (B) Nicotinic acid, (C) Thiamine, (D) Pyridoxine
Answer is D. Pyridoxal phosphate (PLP), coenzyme form of vitamin B6 is the prosthetic group of all aminotransferases. During transamination, PLP serves as a "carrier" of amino groups. An enzyme-bound Schiff base is formed between the keto group of enzyme-bound PLP and the a-amino group of an a-amino acid.