Which of the following statement are true regarding asthma?: (A) Occlusion of bronchi and bronchioles by mucus, (B) Curschmann spirals, (C) Charcot-Leyden crystals, (D) All of the above
Answer is D. Sputum or bronchoalveolar lavage specimen findings - Curschmann spirals (extrusion of mucus plugs from subepithelial mucous gland ducts or bronchioles). Numerous eosinophils and Charcot-Leyden crystals; the latter are composed of an eosinophil protein called galectin-10. Creola bodies The other characteristic histologic findings of asthma, collectively called "airway remodeling".