Hallervorden-Spatz disease: (A) Is an iron storage disorder in brain, (B) Most commonly occurs in adults, (C) Relentlessly non progressive disease, (D) Inherited as Autosomal dominant
Answer is A. It's a rare disorder characterized by progressive extrapyramidal dysfunction and dementiaA form of familial (inherited recessively-linked to chromosome 20) brain degeneration characterized by iron deposition in the brainA mutation in the pantothenate kinase gene has been describedMRI shows "eye-of-the-tiger sign"The disease is relentlessly progressive and the affected individuals typically die in 2nd or 3rd decade(ref:Harrison 18th /e p2251)