Which of the following is the most common tumour associated with Neurofibromatosis -1 (NF-I) in a child?: (A) Juveile Myelomonocytic Leukemia (JMML), (B) Acute Lymphoblastic Leukemia (ALL), (C) Acute Myeloid Leukemia (AML), (D) Chronic Myeloid Leukemia (CML)
Answer is A. Children with neurofibromatosis type 1 have higher risk of developing juvenile myelomonocytic leukemia. Ref: Essential pediatrics by O.P.Ghai 6th edn/page 545; Rook's textbook of dermatology, Volume 1 By Ahur Rook, Tony Burns (FRCP.)page 2-32.