A patient who was given primaquine develops dark coloured urine one day after administration of the drug. The likely diagnosis is -: (A) Glucose-6-phosphate dehydrogenase deficiency, (B) Glucose-6-phosphate deficiency, (C) Galactose-6-phosphate dehydrogenase deficiency, (D) Galactose-6-phosphataase deficiency
Answer is A. Ans. is 'a' i.e., Glucose-6-phosphate dehydrogenase deficiency o Development of dark coloured urine within one day of administration of primaquine suggests the possibility of intravascular hemolysis and hemoglobinuria. Primaquine can cause hemolysis in patients with G6PD deficiency.