Sickle cell anemia is the clinical manifestation of homozygous genes for an abnormal hemoglobin molecule. The event responsible for the mutation in the B chain is:: (A) Insertion, (B) Deletion, (C) Nondisjunction, (D) Point mutation
Answer is D. Ans. D. Point mutationThe mutation in HbS is an example ofPoint mutationPartially acceptable mis-sense mutationTransversionBase substitution.Nonconservative mutation