A child died soon after bih. On examination, there was hepatosplenomegaly and edema all over the body. Coombs test negative in the mother. Most probable diagnosis: (A) Beta thalassemia, (B) Alpha thalassemia, (C) Hereditary spherocytosis, (D) ABO incompatibility
Answer is B. Alpha thalassemia is a blood disorder that reduces the production of hemoglobin. Affected individuals also have a shoage of red blood cells (anemia), which can cause pale skin, weakness, fatigue, and more serious complications. Two types of alpha thalassemia can cause health problems. Reference: GHAI Essential pediatrics, 8th edition