Goodpasture's syndrome is characterised by :: (A) Necrotising haemorrhagic interstitial pneumonitis, (B) . Alveolitis, (C) Patchy consolidation, (D) Pulmonary oedema
Answer is A. Necrotising haemorrhagic interstitial pneumonitis Goodpasture's syndrome is an uncommon autoimmune disease. It shows presence of circulating autoantibiodies against non collagenous domain at a-3 chain of collagen IV. These antibodies initiate inflammatory distruction at basement membrane in glomeruli & lung alveoli, giving rise to RPGN & necrotising haemorrhagic interstitial pneumonitis.