The gold standard for diagnosis of gastroesophageal reflux disease (GERD) is:: (A) Barium swallow, (B) Endoscopy, (C) 24-hours pH monitoring, (D) Esophageal manometry
Answer is C. Barium swallow- IOC for diagnosis of Hiatus hernia and Zenker's diveicula Endoscopy + Biopsy- IOC for diagnosis of Barret's esophagus 24 hours PH monitoring- Gold standard Investigation for GERD Esophageal manometry- IOC for diagnosis of motility disorders of esophagus like Achalasia cardia, Diffuse esophageal spasm and Nut cracker's esophagus.