Pyruvate Dehydrogenase complex has all enzyme components EXCEPT:: (A) Pyruvate Dehydrogenase, (B) Dihydrolipoyl Transacetylase, (C) Dihydrolipoyl Dehydrogenase, (D) Pyruvate Decarboxylase
Answer is D. PDH complex has 3 enzyme components: 1. E1: Pyruvate Dehydrogenase 2. E2: Dihydrolipoyl Transacetylase 3. E3: Dihydrolipoyl Dehydrogenase REGULATION OF PDH End Product Inhibition Covalent Modification Acetyl CoA (in fasting) NADH Active in dephosphorylated state Done by Insulin