Treatment of multiple carboxylase deficiency ?: (A) Biotin, (B) Pyridoxine, (C) Thiamine, (D) Folic acid
Answer is A. Ans. is 'a' i.e., Biotin Pathogenesis of multiple carboxylase deficiency o Deficiency of either holocarboxylase synthase or biotinidase impaires biotin metabolism. o Biotin is a cofactor for various carboxylases in the body ? o Impaired metabolism of biotin results in multiple carboxylase deficiency. o So, for the treatment of multiple carboxylase deficiency, biotin should be given.