Fibroblast Growth Factor mediates effect through which of the following receptor?: (A) Tyrosine kinase, (B) cAMP, (C) cGMP, (D) Ca2+
Answer is A. Fibroblast Growth Factor (FGF) contain more than 20 members. FGFs transduce signals through four tyrosine kinase receptors (FGFRs 1-4). FGF-1 binds to all receptors. FGFs contribute to wound healing responses, hematopoiesis, angiogenesis, development, and other processes through several functions. Ref: Robbins 8th edition Chapter 3.