In minimal change disease, which of the following is seen?: (A) Immunodeposits in glomerulus, (B) Immunodeposits in mesangium, (C) Immunodeposits in blood vessels, (D) No immunodeposits
Answer is D. d. No immunodeposits(Ref: Nelson's 20/e p 2521-2528, Ghai 8/e p 477-482)In minimal change disease:Light microscopy: Glomeruli appear normal: No Ig/complement deposits, GBM: normalImmunofluorescence microscopy: No electron-dense depositsElectron microscopy: Diffuse effacement of foot processes of podocytes ("podocytopathy").