Which of the following drugs is associated with the untoward side effect of renal tubular damage?: (A) Cisplatin, (B) Streptozocin, (C) Methysergide, (D) Cyclophosphamide
Answer is A. Cisplatin is a highly emetic and nephrotoxic agent.
Streptozocin causes the destruction of β-cells of the pancreas and may result in hyperglycemia.
Methysergide can cause retroperitoneal fibrosis on long-term use.
Cyclophosphamide can result in hemorrhagic cystitis.