Pentostatin acts by inhibiting: (A) RNA dependent DNA polymerase, (B) Aldolase, (C) Aldenosine deaminase, (D) Adenylyl cyclase
Answer is C. Ref-Katzung 10/920 Pentostatin and cilastatin are not statins i.e. these do not act by inhibiting HMG-CoA reductase. Pentostatin acts by inhibiting adenosine deaminase. It is used for the treatment of hairy cell leukemia. Drug of choice for hairy cell leukemia is cladribine.