Which of the following muscle relaxant undergo Hoffman's degradation?: (A) Atracurium, (B) Succinylcholine, (C) Gallamine, (D) Pancuronium
Answer is A. Atracurium is an intermediate acting nondepolarizing neuromuscular blocker which is inactivated in the plasma by spontaneous nonenzymatic degradation (Hoffman's elimination) in addition to that by cholinesterase.