Which of the following production is noted in Cushing's Syndrome a tumour associated ?: (A) Decrease production of coisol, (B) Increase production of coisol, (C) Excessive production of epinephrine, (D) Excessive production of vasopressin
Answer is B. Ans. is 'b' i.e., Increase production of coisol Cushing syndrome o Cushing syndrome is characterized by an excess production of coisol. o The most common cause of cushing syndrome is exogenous hypercoisolism, administration of exogenous glucocoicoids. o The cause of endogenous hypercoisolism (endogenous cushing syndrome) are : - i) ACTH producing pituitary m7icroadenoma -* o It is the most common cause of endogenous hypercoisolism and this form of cushing syndrome is referred to as cushing disease. ii) Hypersecretion of corisol by an adrenal adenoma, carcinoma or nodular hyperplasia. iii) The secretion of ectopic ACTH by a nonendocrine neoplasm, e.g., small cell carcinoma of lung.