Radiotherapy is most useful in which of the following: March 2010: (A) Choriocarcinoma, (B) Osteosarcoma, (C) Seminomas, (D) Renal cell carcinoma
Answer is C. Ans. C: Seminomas Radiotherapy may be effective alone, or may require the addition of cytotoxic chemotherapy as in the more advanced stages of a Wilm's tumour and Hodgkin's disease. Radiosensitive tumor includes: Malignant lymphomas Seminomas Medulloblastoma Neuroblastoma Wilm's tumour Early cervical carcinoma Vaginal carcinoma Most head and neck tumours Radioresistant tumours are those that do not respond to radiotherapy. This group includes: Osteosarcoma Fibrosarcoma Liposarcoma Myosarcoma Malignant melanoma Large bowel adenocarcinomas Gliomas