Which interleukin is associated with fever and inflammation?: (A) Interleukin 1, (B) Interleukin 12, (C) Interleukin 5, (D) Interleukin 2
Answer is A. IL-1 is the most important cytokine responsible for the systemic effects of inflammation.
IL-1, IL-6, TNF α and  type 1 interferons contribute to acute phase response.