Which of the following statements concerning immunoglobulins is wrong:: (A) IgM does not cross placenta, (B) IgE increased in parasitic infection, (C) IgM increased in primary response, (D) Fetal infection can be diagnosed by detection of IgG
Answer is D. Only IgG can cross placenta, other classes cannot cross placenta. Hence fetal infection cannot be diagnosed by IgG, IgM is the predominant antibody present in primary immune response. Levels of IgE are markedly raised in parasitic infections.