Histamine blocker in stomach act through: (A) Decreasing cAMP in stomach, (B) Increasing cAMP in stomach, (C) Increasing IP3 in stomach, (D) Decreasing IP3 in stomach
Answer is D. Histamine H2 blockersinhibit the action of histamine ongastric H2 receptors thereby decreasing gastric acidity. They were considered a breakthrough in the treatment of peptic ulcer disease when first introduced. Refer kDT 6/e 153