FNAC can diagnose all of the following thyroid lesions except: (A) Anaplastic carcinoma, (B) Papillary carcinoma, (C) Follicular carcinoma, (D) Medullary carcinoma
Answer is C. Ans. (c) Follicular carcinomaRef: Bailey & Love 24th/ 785y Schwartz 8th /1420* FNA biopsy is unable to distinguish benign follicular lesions from follicular carcinoma. Therefore, preoperative diagnosis of cancer is difficult unless distant metastases are present. Large follicular tumors (>4cm) in older men are more likely to be malignant. --Schwartz Surgery* FNAC is the investigation of choice for solitary thyroid nodules.* It cannot distinguish between a follicular Adenoma and a Follicular Carcinoma as this distinction is dependent not on cytology but on histological criteria such as capsular and vascular invasion. It therefore cannot be used to diagnose follicular carcinomas.