All are true regarding intestinal type of gastric carcinoma Except:: (A) Well defined gland formation, (B) Most common site is distal pa of stomach, (C) Lymphatic spread, (D) More common in elderly
Answer is C. Lauren's classification of stomach cancer Intestinal variety Diffuse variety Classical MC- elderly males (50-60 years) MC site- distal stomach Environmental risk factors Well defined gland formation Hematogenous spread APC gene mutation Epidemic Atypical MC- young females MC site- fundus/proximal stomach Familial risk factors Poor gland formation- signet ring variety Lymphatic spread Decreased E- cadherin Endemic