Early epiphyseal closure is seen with _________: (A) LH, (B) FSH, (C) Estrogen, (D) Progesterone
Answer is C. The growth velocity decreases and may even be zero after epiphyseal fusion, that is, after growth plate closure in late pubey. Precocious pubey (PP) is a known cause of sho stature after earlier pubey due to premature closure of growth plates in long bones Precocious pubey may be due to increased estrogen . Ref : Nelson paediatrics Chapter : Growth and deve