Eosinophils are activated by -: (A) IL 1, (B) IL 5, (C) IL 4, (D) IL6
Answer is B. IL 5 activates eosinophils that are recruited to the area. Mediate type 1 hypersensitivity. Basic Pathology, Robbins. Page no.: 111 Interleukin-5 is produced by a number of cell types, and is responsible for the maturation and release of eosinophils in the bone marrow. In humans, interleukin-5 is a very selective cytokine as a result of the restricted expression of the interleukin-5 receptor on eosinophils and basophils Also activates eosinophil