True about competitive inhibition with first order kinetics: (A) Km increased, Vmax same, (B) Vmax increased, Km same, (C) Km same, Vmax decrease, (D) Km same, Vmax increase
Answer is A. Ans. (a) Km increased, Vmax sameType of InhibitionKmVmaxCompetitive inhibitionINCREASEDSAMENon-competitive inhibitionSameDECREASEDCompetitive Inhibtion: Substrate and inhibitor, both compete for same site on enzyme.Non-competitive Inhibition: Substrate and inhibitor both bind at different sites in the enzyme.