The main cytokine, involved in erythema nodosum leprosum (ENL) reaction is –: (A) Interleulcin – 2, (B) Interferon – gamma, (C) Tumor necrosis factor – alpha, (D) Macrophage colony stimulating factor
Answer is C. Most important cytokine for Type II lepra reaction (ENL) is tumor necrosis factor (TNF- α).