HLA is present on –: (A) Short arm of chromosomes 6, (B) Short term of chromosomes 3, (C) Long arm of chromosomes 3, (D) Long arm of chromosomes 6
Answer is A. o HLA complex (MHC) gene is located on the short arm of chromosome 6.
o The histocompatibility antigens (human leukocyte antigens - HLA) are cell surface antigens that induce
an immune response leading to the rejection of allografts.
o The principal physiologic function of the cell surface histocompatibility molecules is to bind peptide
fragments of foreign proteins for presentation to antigen-specific T cells.
o The histocompa