Meningococcal meningitis is seen with which of the following complement deficiency?: (A) C1q, (B) C2, (C) C4, (D) C5
Answer is D. o C5-C9 -complement deficiency (MAC) membrane attack complex o Late complement deficiency are prone for recurrents Neisserial infections (meningo & gonococci both) o C1 esterase inhibitor deficiency: leads to Hereditary Angioneurotic edema