A 3-year-old child came to OPD with bruising and generalized petechiae. No hepatosplenomegaly or lymphadenopathyis noted. He have ahistory of viral illness 2 weeks back. On investigation a normal hemoglobin, hematocrit, and white blood cell (WBC) count and differential. The platelet count is 19,000/iL. All of the following are associated with above illness except?: (A) Ebstein-Barr virus, (B) HIV, (C) Helicobacter pylori, (D) Cytomegalo virus
Answer is D. The diagnosis is ITP. It is the most common form of thrombocytopenic purpura in children. Associated with Ebstein-Barr virus, HIV, Helicobacter pylori Clinical features:- Generalized petechiae and purpura, bleeding from the gums and mucous membranes, Splenomegaly, lymphadenopathy, bone pain, and pallor. Lab findings Platelets count <20,000/mm3 Coagulation normal Platelet size normal/increased Bone marrow- Increased Megakaryocytsis Treatment:- Platelet transfusion IV Ig IV anti D therapy Splenectomy Rituximab