Most common gene responsible for hereditary hemochromatosis is?: (A) HJV gene, (B) HAMP gene, (C) TfR2 gene, (D) HFE gene
Answer is D. harshmohan textbook of pathology 7th edition. *idiopathic haemochromatosis associated with over expression of HFE gene located on chromosome no 6 close to HLA gene locus and normally regulate intestinal absorption of iron.