Leading cause of ACTH independent Cushing syndrome is?: (A) Adrenocoical carcinoma, (B) Macro-nodular adrenal hyperplasia, (C) Micro-nodular adrenal hyperplasia, (D) Adrenocoical adenoma
Answer is D. ACTH independent Cushing Syndrome : constitutes 10% of total cases of Cushing syndrome. The causes of ACTH independent Cushing syndrome: Adrenocoical adenoma (MC) Adrenocoical carcinoma Macro-nodular adrenal hyperplasia (<1%) The most common cause( MCC) of ACTH dependant Cushing syndrome is Pituitary coicotroph adenoma.