Treatment of choice for chronic ulcerative colitis is: (A) 5 aminosalicylic acid, (B) Azathioprine, (C) Metronidazole, (D) Salicylates
Answer is A. In mild to moderate cases of ulcerative colitis, the combination of a once-daily oral and a topical 5-aminosalicylate preparation is effective. MOA of the drug is it modulate cytokine release from mucosa. Reference : Davidson, 23rd Edition, page no : 820.