A 45 year old patient presents with history of fever, night sweats and weight loss. On X-ray, a mass in apical lobe of lung is seen. On histopathology, it was found to have caseous necrosis. What is the likely underlying process involved -: (A) Enzymatic degeneration, (B) Hypersensitivity reaction with modified macrophages, lymphocytes and giant cells, (C) Acute decrease in blood supply, (D) Decreased supply of growth factors
Answer is B. . Hypersensitivity reaction with modified macrophages, lymphocytes and giant cells