The expression of the following oncogene is associated with a high incidence of Medullary carcinoma of thyroid-: (A) P 53, (B) Her 2 neu, (C) RET protooncogene, (D) Rb gene
Answer is C. Harshmohan textbook of pathology 7th edition. RET gene is a proto oncogene normally code for receptor for growth factor ( RET receptor). Point mutation to this gene causes multiple endocrine neoplasi type 2A, type2B , medullary carcinoma of thyroid..