Which of the following is True regarding intraocular retinoblastoma?: (A) 60% are familial and the rest about 40% occur sporadically., (B) Leukocoria or yellowish-white pupillary reflex is 2nd commonest presenting feature., (C) ICRB is presently being followed to decide the treatment modality, (D) All of the above
Answer is C. Retinoblastoma MC ocular tumor of childhood. 40% are hereditary, aka Germline retinoblastoma. B/L, multifocal, earlier presentation 60% are non hereditary or sporadic U/L, later presentation C/F: Leucocoria(Amaurotic cat's eye pupil)- MC presentation Strabismus(2nd MC) Neo vascular glaucoma(3rd MC) International classification of retinoblastoma (ICRB), which is presently being followed worldwide to decide the treatment modality.