Which of the following is not the effect of ranitidine as compared to cimetidine?: (A) Action on H2 receptors, (B) Given orally, (C) Used with proton pump blockers, (D) Anti-androgenic action
Answer is D. Ans. d (Anti-androgenic action). (Ref. Pharmacology by KD Tripathi 5th/- 590)RANITIDINE AS COMPARED TO CEMETIDINE# 5 times more potent# Has no anti-androgenic action# Less CNS penetration# No interaction with hepatic metabolism of other drugs.# Hepatic injury, hematological adverse effects not seen.