Best stain for cryptococcal capsule -: (A) Gram stain, (B) India ink preparation, (C) Giemsa stain, (D) Methanamine-silver stain
Answer is B. Ans. is 'b' i.e., India Ink preparation * C. neoformans is best demonstrated in CSF by direct microscopy. The capsule is seen as a clear halo around the yeast cells in unstained wet preparations of CSF mixed with a drop of India ink or nigrosine. Methenamine silver stain would be the best choice for a tissue sample.