Most common enzyme deficiency among these which leads to childhood hypertension:: (A) 21 hydroxylase deficiency, (B) 11-beta hydroxylase deficiency, (C) 3-beta hydroxysteroid dehydrogenase deficiency, (D) 17-alpha hydroxylase deficiency
Answer is B. Ans. B. 11-beta hydroxylase deficiencyChildhood hypertension and salt retention are seen in children with 11-beta hydroxylase deficiency and 17-alpha hydroxylase deficiency. The second most common cause of CAH (after 21 hydroxylase deficiency) is 11-beta hydroxylase deficiency.