Bile acid synthesis is autoregulated by the enzyme:: (A) 7-Alpha hydroxylase, (B) 11-alpha hydroxylase, (C) Acetoacetyl-CoA thiolase, (D) Desmosterol reductase reductase
Answer is A. 11-alpha hydroxylase Conves 11-deoxycoisol to 11-alpha coisol (the 11-alpha isomer of hydrocoisone) Bile acid synthesis is autoregulated by 7-hydroxylase, the initial enzyme in cholesterol degradation Other enzymes are involved in cholesterol biosynthesis. Ref: Harrison, E-18, P-2462.