HIV mostly affects which cells?: (A) CD4 cells, (B) CD 8 cells, (C) T cells, (D) Plasma cells
Answer is A. harshmohan textbook of pathology 7th edition. *the pathogenesis of HIV infection is largely related to the depletion of CD4 + T cells resulting in preformed immunosuppression .Selective tropism for CD4+ molecule receptors, gp 120 envelope glycoprotein of HIV has selective tropism for the cells containing CD 4 molecules on their surface,most impoantly CD4+T cells