Most common presentation of neuroblastoma is –: (A) Lytic lesion in skull with suture diasthesis, (B) Lung metastasis, (C) Renal invasion, (D) Secondaries in brain
Answer is A. Most frequent site of metastasis from neuroblastoma is bone : where metastasis occurs very early.
Lytic lesions in skull and sutural diastasis are manifestations of bony metastasis to skull, and hence the earliest feature, amongst the options in the questions.