All the following is characteristic of uncompetitive inhibition except: (A) Inhibitor is not a substrate analogue, (B) Inhibitor binds to the active site, (C) Inhibitor binds to the ES complex, (D) Vmax and Km decreased
Answer is B. An uncompetitive inhibitor binds at a site distinct from the substrate active site and, unlike a competitive inhibitor, binds only to the ES complex. Ref: KD Tripathi 8th ed