Leucocyte alkaline phosphatase (LAP) is raised in all conditions except:: (A) Myelofibrosis, (B) Essential thrombocythemia, (C) Chronic myeloid leukaemia, (D) Polycythemia
Answer is C. Low LAP scores have been associated with CML, PNH, thrombocytopenic purpura, and hereditary hypophosphatasia. In CML regardless of the total white count, the score remains low.