Holt-Oram syndrome is characterized by?: (A) ASD, (B) VSD, (C) TGA, (D) TAPVC
Answer is A. Holt-Oram syndrome: - Autosomal dominant disorder - Characterized by - skeletal abnormalities of hands and arms like: Hypoplastic/ absent thumbs, radii Triphalangism Phocomelia - Cardiac anomalies ASD 1st degree hea block TRIPHALANGISM phacomelia