Which of the following increases secretion of GH?: (A) Senescence, (B) Insulin-like growth factor-1 (IGF-1), (C) Somatostatin, (D) Hypoglycemia
Answer is D. Hypoglycemia is a potent stimulus for GH. GH decreases with aging and in response to the hypothalamic inhibitory hormone somatostatin. GH secretion would decrease in response to both exogenous GH administration and IGF-1 as a result of negative feedback inhibition