Sildenafil acts by inhibiting?: (A) PDE 2, (B) PDE 5, (C) Adenyl cyclase, (D) Gaunyl cyclase
Answer is B. Sidenafil, verdenafil, tadalafil acts by inhibiting PDE5 they increase NO- increases blood supply to the penis making it erect But they can produce ceain cardiac events They are also used in Pul HTN Ref: KD tripathi 8th ed