If there is a Gs alpha subunit gain-of function mutation, this results in: (A) Decreased cAMP, (B) Decreased IP, (C) Increassed GTPase activity, (D) Increased cAMP
Answer is D. The Gs alpha subunit (Gas, Gsa) is a subunit of the heterotrimeric G protein Gs that stimulates the cAMP-dependent pathway by activating adenylyl cyclase. Gsa is a GTPase that functions as a cellular signaling protein Ref-Harper 28/e p447