Analgesic effect of paracetamol is mediated by action on which of the following receptor?: (A) NK 1, (B) BK 1, (C) Px23, (D) TRPV 1
Answer is D. PCM uses - Fever Pain Not for inflammation Peroxide:- Presence of peroxide at inflammation site inactivate PCM. COX3 inhibitor :- Presence of COX3 in brain, therefore fever and pain can be treated with PCM. Vanilloid receptor:-Metabolites of PCM binds with vanilloid receptor to produce analgesia. Transient Receptor Potential vanilloid 1:TRPV 1