Ethambutol is avoided in children as it causes -: (A) Dental maldevelopment, (B) Visual disturbance, (C) Renal failure, (D) Growth retardation
Answer is B. Ans. is 'b' i.e., Visual disturbanceo The main adverse effect of Ethambutol is retrobulbar optic neuritis (unilateral or B/L).o This causes loss of visual activity, red-green colour blindness, central scotoma, peripheral vision loss.o The changes reverse, if the t/t is stopped promptly if not, the patient may go blind.o Children below 6 years of age are not given ethambutol because children are unable to report early visual deterioration.o Ethambutol also produces hyperuricemia.