Lymphocyte phenotype test done for?: (A) Agammaglobinemia, (B) SCID, (C) Sepsis, (D) Acute leukemia
Answer is B. Ans. (b) SCID(Ref: HENRY'S Clinical Diagnosis and Management by Laboratory Methods; 22ned ed/ pg 944-945)Lymphocyte phenotyping for assessing immune deficiency includes CD3 (pan T cell), CD4 (T helper subset), CD8 (T cytotoxic/suppressor subset), CD 19 (pan B cell), CD 16/56 (pan NK cell) and other cell surface markers as required based on clinical data. This analysis is indicated in diagnosis and monitoring of immunodeficiencies and immunotherapy in children and adults