Primary metabolic bone disorder in scurvy is ?: (A) Decreased mineralization, (B) Decreased osteoid matrix formation, (C) Increased bone resorption, (D) Decreased bone mass with normal mineralization and osteoid formation
Answer is B. Ans. is 'b' i.e., Decreased osteoid matrixo Collagen is a component of osteoid (protein matrix).o Collagen synthesis is deficient in scurvy; therefore, osteoid formation is defective.o On the other hand, in rickets osteoid formation is normal, but mineralization (Calcification) of osteoid is defective.