Pendred&;s Syndrome is due to defect in:: (A) Chromosome 7p, (B) Chromosome 7q, (C) Chromosome 8p, (D) Chromosome 8q
Answer is B. Pendred&;s Syndrome: Consists of congenital sensorineural hearing loss+ goitre Due to defects in sulfate transpo protein (Chromosome 7q) to the thyroid gland and cochlea. Rafetoff Syndrome End organ resistance to T4 Ref: Schwaz 10th edition Pgno: 1534