Which of these drugs DO NOT decrease angiotensin II activity:: (A) Enalapril, (B) Valsartan, (C) Nesiritide, (D) Omapatrilat
Answer is C. ACE inhibitors and ATi antagonists decrease angiotensin II activity.
Omapatrilat is a vasopeptidase inhibitor that acts by inhibiting two enzymes, ACE and NEP. As it inhibits ACE, it may also decrease angiotensin II activity.
Nesiritide is a recombinant BNP and has no effect on angiotensin II activity.