Provisional sho antiretroviral regime given in the peripaum period reduces the risk of veical transmission by: (A) 35%, (B) 50%, (C) 65%, (D) 75%
Answer is B. Most transmission of HN occurs during pregnancy and bih, breastfeeding may account for 5-15% of infants becoming infected after delivery Studies have demonstrated that truncated regimens of zidovudine alone or with Lamivudine given to mother during last few weeks of pregnancy or even during labour & delivery & to the infant for a week or less reduced transmission to infant by 50% compared to placebo. rEF : katzung 12 th ed.