Ductus arteriosus closes in response to:: (A) Decrease in peripheral oxygen saturation, (B) Indomethacin therapy, (C) Prostaglandin E1, (D) Increase in pulmonary vascular resistance
Answer is B. b. Indomethacin therapy(Ref: Nelson's 20/e p 2197, Ghai 8/e p 417)Indomethacin, a Prostaglandin inhibitor is used in medical closure of Ductus arteriosus.