A bolus of drug K is given IV. The drug is noted to follow first order kinetics. Which of the following describe the elimination of drug K: (A) The rate of elimination of drug K is propoional to its concentration in the patient's plasma., (B) The rate of elimination of drug K is dependent on a nonlinear relationship to the plasma protein concentration., (C) The rate of elimination of drug K is constant., (D) The rate of elimination of drug K is propoional to the patient's renal function.
Answer is A. First-order kinetics means the rate of elimination of a drug is propoional to the plasma concentration. Ref:- KD Tripathi