Siltuximab is used in treatment of ?: (A) Castlemans disease, (B) Sezary syndrome, (C) Ankylosing spondylitis, (D) Non hodgkins lymphoma
Answer is A. Ans. is 'a' i.e., Castleman's diseaselRef: Multiple myeloma, an issue of hematology oncology clinics E boohKenneth C Anderson p. 9171Siltuximab (Anti IL-6):IL-6 is produced by the stromal cells of the bone marrow, and plays a crucial role in the proliferation and survival of multiple myeloma cells.