Auto antibody in Sjogrens syndrome is?: (A) Anti centromere antibody, (B) Anti Ro & anti La, (C) Anti ds DNA, (D) Anti RNP
Answer is B. Robbins basic pathology 9th edition page no 131,(green box=Pathogenesis) Most patients with primary sjogren syndrome have auto antibodies to the ribo-nucleoprotien (RNP) antigensSS-A(RO) and SS-B(la).