Which drug is not used now in Alzheimer's disease?: (A) Tacrine, (B) Galantamine, (C) Donepezil, (D) Rivastigmine
Answer is A. Ans. (A) Tacrine(Ref: KDT 8th/e p119, 518)Because of hepatotoxicity, and requirement of frequent dosing, tacrine is less often used than other agents.