HMG-CoA can be directly conveed to all except?: (A) Acetoacetate, (B) Acetyl-CoA, (C) Mevalonate, (D) Aceto-acetyl CoA
Answer is D. Ans. is 'd' i.e., Aceto-acetyl CoA Acetoacetate & Acetyl - CoA are derived from HMG-CoA during ketogenesis by HMG-CoA lyase which breaks the HMG-CoA into acetoacetate and acetyl-CoA during ketogenesis.Mevalonate is formed directly from HMG-CoA in cholesterol synthesis.HMG-CoA is conveed to mevalonate by HMG-CoA reductase, the key regulatory enzyme of cholesterol synthesis.