Isoprostanes are formed from archidonic acid by -: (A) Cycloxygenase, (B) Lipoxygenase, (C) Epoxide hydrolase, (D) Non-enzymatic free radical peroxidation
Answer is D. isoprostanes are prostaglandin stereoisomers Cycloxygenase pathway Thrombaxne and prostaglandin are formed Lipoxyenase pathway leukotienes are formed these are formed by Non-enzymatic free radical peroxidation of AA these have potent vasoconstrictor activity and modulate WBC and platelet adhesion ref robbins 9th ed page 84