During the treatment with rifampicin some patients will have mild elevation in the bilirubin with normal transaminases.This is due to:: (A) Hemolysis, (B) Transient cholestasis with bile duct injury, (C) Microsomal enzyme induction, (D) Hepatic adaptation
Answer is D. One form of hepatic adaptation includes drug induced hyperbilirubinemia , it is seen with rifampicin,flavaspidic acid,cyclosporine. Ref : Schiff's diseases of liver , Edition -11 , Page - 715.