Which of the following muscle is blocked first by neuromuscular blocker:-: (A) Face, (B) Proximal limb, (C) Diaphragms and vocal cords, (D) Distal limb
Answer is C. Neuromuscular blockade usually sooner occur at well perfused centrally located muscles (diaphragm or vocal cords ) than at peripheral locations (hand or foot). Recovery occurs also in same sequence thus diaphragm and vocal cords , face, proximal limbs and distal limbs. Sequence of NM paralysis and recovery from paralysis is sameDiaphragm & vocal cords - Head & Neck - Upper Limb - Trunk - Lower Limb