Which of the following is not a minor diagnostic criteria for multiple myeloma?: (A) Lytic bone lesions, (B) Plasmacytosis greater than 20%, (C) Plasmacytoma on biopsy, (D) Monoclonal globulin spike on serum electrophoresis of > 2.5 g/dl for IgG, >1.5 g/dl for IgA
Answer is C. Ans. (c) Plasmacytoma on biopsy(Ref: Wintrobes 12th/pg2377)Durie and Salmon criteria for diagnosis of Multiple myeloma.A minimum of 1 major and 1 minor criterion needed, although (1) + (a) is not sufficient, or 3 minor criteria that must include (a) and (b).However, International myeloma working group 2011 has revised the criteria as mentioned in pretexts.