Dose of benzanthine penicillin in early syphilis is _________: (A) 3-4 million units intravenously, (B) 2.4 million units intramuscularly as a single injection, (C) 2.4 million units intramuscularly daily, plus probenecid 500 mg orally for 14 days, (D) 2.4 million units intramuscularly weekly for three doses
Answer is B. 2.4 million units intramuscularly as a single injection is the dose of benzanthine penicillin early syphilis. Early syphilis: Benzanthine penicillin G, 2.4 million units intramuscularly weekly for three doses. More than 1-year duration: Benzanthine penicillin G, 2.4 million units intramuscularly weekly for three doses. Neurosyphilis: Aqueous crystalline penicillin G, 3-4 million units intravenously every 4 hours for 10-14 days or Aqueous procaine penicillin, 2.4 million units intramuscularly daily, plus probenecid 500 mg orally four times daily, both for 10-14 days. Ref: Willams Obstetrics 25th edition Pgno: 1238