In case of hepatic porphyria the safe anticonvulsant is: (A) Clonazepam, (B) Paraldehyde, (C) Phenytoin, (D) Carbamazepine
Answer is A. (A) Clonazepam > Seizures can be due to neurologic effects or to hyponatremia.> Treatment of seizures is difficult because virtually all antiseizure drugs (except bromides) may exacerbate> AIP (clonazepam may be safer than phenytoin or barbiturates).