Diagnostic test for CSF rhinorrhea is ?: (A) Beta - 2 microglobulin, (B) Beta - 2 transferrin, (C) Thyroglobulin, (D) Transthyretin
Answer is B. Ans. is 'b' i.e., Beta-2 transferrin Beta-2 transferrin is a CSF-specific variant of transferrin and is used as an endogenous marker of CSF leakage. Beta-2 transferrin is formed by loss of sialic acid due to the presence of neuraminidase in the central nervous system. Beta-2 transferrin has also been called CSF-specific transferrin and tau protein.