What does the term "bioavailability" mean?: (A) Plasma protein binding degree of substance, (B) Permeability through the brain-blood barrier, (C) Fraction of an uncharged drug reaching the systemic circulation following any route administration, (D) Amount of a substance in urine relative to the initial doze
Answer is C. Bioavailability is defined as the fraction of unchanged drug reaching the systemic circulation following administration by any routeBasic and clinical pharmacology Katzung 13th edition pg 47