About first order kinetics true statement is: (A) Clearance remains constant, (B) Fixed amount of the drug is eliminated, (C) Half life increase with dose, (D) Decreased clearance with increasing dose
Answer is A. I 1st order reaction half life remains constant and clearence remains constant In zero order reaction half life decrease with decrease in concentration Ref:Guyton and Hall textbook of medical physiology 12th edition,page number:489,490