Vitamin K leads to?: (A) g-carboxylation of aspaic acid residues to clotting factor 2,7,9 and 10, (B) b-carboxylation of glutamic acid residues to clotting factor 2,7,9 and 10, (C) alpha - carboxylation of asparatic acid residues to clotting factor 2,7,9 and 10, (D) g-carboxylation of glutamic acid residues to clotting factor 2,7,9 and 10
Answer is D. Vitamin K leads to g-carboxylation of glutamic acid residues to clotting factor 2,7,9 and 10 Vitamin K is essential for adding carboxyl group to glutamic acid residues on 5 impoant clotting factors 1. Prothrombin (II) 2. Factor VII 3. Factor IX 4. Factor X 5. Protein C