Romana's sign is seen in?: (A) Toxoplasma, (B) Trypanosoma cruzi, (C) Loa loa, (D) Wuchereria
Answer is B. Ans. (b) Trypanosoma cruzi Romana sign, also known as chagoma, refers to periorbital swelling, palpebral oedema and conjunctivitis seen 1-2 weeks following infection with Trypanosoma cruzi (causative agent in Chagas disease). Romana sign is associated with ipsilateral regional lymphadenopathy. History and etymology It is named after Cecilio Felix Romana (1899 - 1997), Argentinian physician, who first described the phenomenon.