L.E. Cell phenomenon in peripheral blood is seen in:: (A) Rheumatic heart disease, (B) Infective endocarditis, (C) Ischemic heart disease, (D) Systemic Lupus Erythernatosus
Answer is D. The addition of blood serum from a person under suspicion to the buffy coat of normal blood is the basis for L.E .cell phenomenon. If the patient is L.E. -we, then typical "LE" Cell develop. The cell consists of rosette of neutrophils surrounding a pale nuclear mass, derived from a Lymphocyte.