Ketogenesis takes place in:: (A) Hepatic mitochondria, (B) Hepatic cytoplasm, (C) Hepatic microsome, (D) Hepatic lysosome
Answer is A. Fatty acid oxidation takes place in mitochondria. Ketogenesis also takes place in mitochondria. HMG-CoA synthase is present in both cytosol and mitochondria. Cytosolic HMG-CoA synthase is involved in cholesterol synthesis. Mitochondrial HMG-CoA synthase is involved in ketogenesis.