The main mechanism of hyperpyrexia induced by atropine is?: (A) Vasodilation, (B) inhibition of sweating, (C) Through central actions, (D) Increase in basal metabolic rate
Answer is B. Ref:KD Tripathi pharmacology 7th edition (page.no: 115) Rise in body temperature by Atropine occurs at higher doses. It is due to both inhibition of sweating as well as stimulation of temperature regulating centre in the hypothalamus.