Molecular classification of breast cancer is based on which of the following: (A) Gene expression profiling, (B) Expression of hormone receptors like ER, PR and HER-2 neu, (C) Histology, (D) Response to chemotherapy
Answer is A. Refer Robbins page no 1061 Invasive carcinoma can be divided based on molecular and morpholog characteristic into several clinically impoant subgroups. Breast carcinoma have a wide variety of morphological apperance.One third can be classified morphologically into special histologic types some of which are strongly assosciated with clinically relevant biologic characteristic