Tumor marker of Dysgerminoma: (A) a-fetoprotein, (B) hCG, (C) CA-125, (D) Lactate dehydrogenase
Answer is D. Dysgerminoma is the most common malignant germ cell tumour, accounting for about 30% to 40% of all ovarian cancers of germ cell origin. Placental alkaline phosphatase (PLAP) and lactate dehydrogenase (LDH) are produced by up to 95% of dysgerminomas, and serial measurements of LDH may be useful for monitoring the disease. Reference: Berek and Novak's Gynecology; 14th edition; Chapter 37; Ovarian, Fallopian Tube, and Peritoneal Cancer