Aggrecan is:: (A) A receptor over platelets, (B) A molecule present in osteoid tissue, (C) Granules in leukocytes, (D) Impoant component of cailage
Answer is D. Aggrecan is a proteoglycan, also known as cailage-specific proteoglycan core protein (CSPCP) or chondroitin sulfate proteoglycan 1. It is encoded by the ACAN gene. Aggrecan is an integral pa of the extracellular matrix (ECM) in cailagenous tissue and it withstands compression in cailage.