Reed Sternberg cells are:: (A) B cells, (B) T cells, (C) Natural killer cells, (D) All of above
Answer is A. Reed-Sternberg (RS) cells are the malignant cells in Hodgkin Lymphoma which is a malignancy of germinal center mature B lymphocytes. These are large cells with abundant cytoplasm with bilobed and/or multiple nuclei These comprise less than 1% of the cellular infiltrate in the lymphoma tissue.