Unorable interaction of drug and substrate in human beings are all except:: (A) Omeprazole reduces stomach acid, (B) Methotrexate inhibiting folate, (C) Barbiturates decreases B 12 absorption, (D) Retinoic acid inhibits vitamin E
Answer is A. Ans. a. Omeprazole reduces stomach acid Omeprazole reduces stomach acid secretion: This interaction is beneficial for patients suffering from GERD without having any associated complications. Rest three interactions has a bad impact on the normal healthy individuals. Methotrexate inhibiting folate Barbiturates decreases 13,2 absorption Retinoic acid inhibits vitamin E