Elevated triglycerides and decreased HDL are seen in?: (A) Smoker, (B) Alcoholics, (C) Athlete, (D) Diabetes
Answer is D. The most common pattern of dyslipidemia in diabetes mellitus is hyperiglyceridemia and reduced HDL levels. Increase free fatty acid flow to the liver - | production of apoB-containing triglyceride-rich VLDLs Hyperiglyceridemia -Excellent marker of the insulin-resistant condition. Thiazides cause dyslipidemia,hyperglycemia hence contraindicated in diabetic hypeensives. Antihypeensive drug of choice:-Angiotensin Conveing Enzyme (ACE) Inhibitors/Angiotensin II Receptor Blockers (ARBs). Metabolic syndrome X - Elevated levels of apoC-III carried on VLDLs Increase apoC-III can inhibit lipoprotein lipase- Hyperiglyceridemia Reduction in HDL cholesterol.