Upper segment : lower segment ratio in Growth hormone deficiency:: (A) Increases, (B) Decreases, (C) Remains unchanged, (D) Cannot comment
Answer is C. - Growth hormone deficiency is a cause of propoionate sho stature - so upper segment : lower segment ratio remains normal or unchanged. CLINICAL FEATURES OF GH DEFICIENCY: Delayed bone age, dentition, pubey, milestones Hypoglycemia Frontal bossing High pitched voice Sho stature DIAGNOSIS: 1. GH stimulation test : Done using insulin/ arginine/ clonidine/ glucagon Peak GH level <10 ng/ml - GH deficiency 2. Bone age < Chronological age Treatment:Recombinant GH injections subcutaneously