Most common mutation in hereditary spherocytosis: (A) Spectrin, (B) Ankyrin, (C) Glycophorin A, (D) Band 3
Answer is B. Ans. (b) Ankyrin(Ref: Robbins 9th/pg 632; 8th/pg 642)Most common mutation:Hereditary spherocytosis is Ankyrin>Band-3>spectrinHereditary elliptocytosis is Spectrin