Most characteristic feature of diabetic nephropathy:: (A) Kimmelstein Wilson change, (B) Armani Ebstein change, (C) Focal segmental glomerulosclerosis, (D) Membrano proliferative glomerulonephritis
Answer is A. Features of diabetic nephropathy are: - Glomerular lesions like Capillary basement membrane thickening - Earliest & most common change in DM Diffuse mesangial sclerosis - presents as nephrotic syndrome in severe cases Nodular glomerulosclerosis aka Kimmelstiel-Wilson lesion - Pathognomonic of diabetes -Renal vascular lesions, principally aeriolosclerosis -Pyelonephritis, including necrotizing papillitis.