Which of the following is not true regarding apoptosis?: (A) Step ladder pattern on agarose gel electrophoresis, (B) Apoptosis is energy independent process., (C) Annexin V is a marker of apoptosis, (D) Caspases are endonucleases
Answer is D. Caspases are cysteinyl aspartate proteinases. They are cysteine proteases that cleave their substrates following an aspartate residue. They will activate endonucleases leading to chromatin clumping.