Antigen idiotype is related to -: (A) Fc fragment, (B) Hinge region, (C) C-terminal, (D) N-terminal
Answer is D. The antigen combining site of the immunoglobulin molecule is at its amino terminus. - it is composed of both L and H chains. - the first 110 amino acid from the N terminal is quite variable in amino acid sequence and this region is called the variable region. - the amino-terminal variable region of light and heavy chain paicipates in the antigen recognition. Reference : Anathanarayan & paniker's 9th edition, pg no: 94, 95 <\p>