A 45 year old lady presented with features suggestive of mononeuritis multiplex. She gives a h/o regular attacks of bronchial asthma preceded by allergic rhinitis. She also has cutaneous purpura. Blood routine examination revealed eosinophilia. The diagnosis to be considered in this clinical scenario is?: (A) Microscopic polyangiitis, (B) Endogenous bronchial asthma, (C) Churg strauss syndrome, (D) Wegeners vasculitis
Answer is C. When small-vessel vasculitis is associated with peripheral eosinophilia, cutaneous purpura, mononeuritis, asthma, and allergic rhinitis, a diagnosis of Churg-Strauss syndrome is considered. Ref: Harrisons Principles of Internal Medicine, 18th Edition, Page 2344