Patient presents with inability to conve pyruvate to Acetyl CoA. Which of the following can be given in treatment:-: (A) Vitamin B3, (B) Thiamine B1, (C) Free fatty acids, (D) Biotin
Answer is B. PDH COMPLEX - three enzymes (1 ) pyruvate dehydrogenase (E1), (2) dihydrolipoyl transacetylase (E2) (3) dihydrolipoyl dehydrogenase (E3) FIVE COENZYME - VITAMIN B1 , B2 , B3 , B5 , COA, LIPOIC ACID Any oxidative decarboxylation reaction in body require vitamin B1 so here answer is the vitamin b1