Acetyl-CoA is transpoed out of the mitochondria in order to serve as a substrate for fatty acid or cholesterol synthesis. Which of the following enzymes used in this transpo process provides NADPH required for these reductive biosynthesis reactions?: (A) ATP-citrate lyase, (B) Citrate synthase, (C) Malate dehydrogenase, (D) Malic enzyme
Answer is D. Do not confuse malic enzyme with malate dehydrogenase. Malate dehydrogenase Malic enzyme Produces NADH Produces NADPH