A patient of parkinsonism is managed with L-dopa. If Vit. B-complex is administered concurrently-: (A) The action of L-dopa in brain will be potentiated, (B) Decarboxylation of L-dopa in brain will be decreased, (C) Side effects will be ameliorated, (D) Decreased efficacy will result
Answer is D. Ans. is 'd' i.e., Decreased efficacy will result "Pyridoxine abolishes the therapeutic effect of levodopa by enhancing peripheral decarboxylation of levodopa".