Epigenetics deals with genetic modification that do not alter the sequence of DNA. All of the following can detect epigenetic modifications except: (A) Chip on chip, (B) Bisulphite method, (C) HPLC, (D) Methylation specific PCR
Answer is C. Methods to detect epigenetic modifications Sequencing Chip on chip (Microarray) Using Methylation specific primers in PCR Bisulphite method: Bisulphite conves unmethylated cytosine to uracil. This can be detected by sequence analysis.