Hypercoagulability and dermal vascular necrosis are early appearing adverse effects of:: (A) Clopidogrel, (B) Heparin, (C) Warfarin, (D) Vitamin K
Answer is C. Oral anticoagulants inhibit the activation of several clotting factors (II, VII, IX and X) as well as anti-clotting proteins (protein C and S). First to disappear is protein C that can result in hypercoagulation resulting in dermal vascular necrosis.