BRCA 1 gene is located on chromosome: (A) 17p21, (B) 17q21, (C) 13p21, (D) 13q21
Answer is B. A BRCA mutation is a mutation in either of the BRCA1 and BRCA2 genes, which are tumour suppressor genes. ... Women with harmful mutations in either BRCA1 or BRCA2 have a risk of breast cancer that is about five times the normal risk, and a risk of ovarian cancer that is about ten to thiy times normal.