In lymphoplasmacytoid lymphoma which of the following monoclonal immunoglobulin is seen?: (A) IgA, (B) IgD, (C) IgG, (D) IgM
Answer is D. Lymphoplasmacytoid lymphoma /Waldenstrom's Macroglobulinemia. The majority of patients in this disease have monoclonal IgM serum para-protein. In contrast to myeloma, the disease was associated with lymphadenopathy and hepatosplenomegaly,but the major clinical manifestation was the hyperviscosity syndrome.