Inheritance of Gardner syndrome is: (A) Autosomal recessive, (B) Autosomal dominant, (C) X linked, (D) None of the above
Answer is B. Gard*ner syn*drome Multiple polyposes predisposing to carcinoma of the colon; also multiple tumors, osteomas of the skull, epidermoid cysts, and fibromas; autosomal dominant inheritance, caused by mutation in the adenomatous polyposis coli gene (APC) on chromosome 5q. This disorder is allelic to familial adenomatous polyposisRef: Harrison &;so manual of Medicine 19th edition Page no: 325