Which of the following drugs used to treat type-II diabetes mellitus causes weight loss: (A) Metformin, (B) Glimepiride, (C) Repaglinide, (D) Gliclazide
Answer is A. Ans. is 'a' i.e., Metformin Effect of antidiabetic drugs on weight Increased : Sulfonylureas, insulin, pioglitazone Decreased : Metformin, GLP-1 antagonists, pramlinitide No effect: DPP-4 inhibitors