In acute liver injury-: (A) AST/ALT ratio < 1 occur in most of the hepatocellular conditions, (B) AST/ALT ratio > 2:1 suggestive of alcoholic liver disease, (C) Synthesis ofAST is inhibite by ethanol, (D) In alcoholic liver disease AST/ALT ratio < 1
Answer is A. AST/ALT ratio.. Most causes of liver cell injury are associated with a greater increase in ALT than AST; however, an AST to ALT ratio of 2:1 or greater is suggestive of alcoholic liver disease, paicularly in the setting of an elevated gamma-glutamyl transferase. Ref Davidson edition23rd pg 852