Mechanism of action of aspirin is inhibition of:: (A) Thromboxane A2 synthesis, (B) Phosphodiesterase, (C) HMG-CoA reductase, (D) Pancreatic lipase
Answer is A. Aspirin inactivates cyclo-oxygenase by irreversible acetylation of the enzyme and thereby inhibit the synthesis of throboxane A2. From medical pharmacology padmaja 4th edition Page no 344