True about SCID in children is:: (A) It is due to adenosine deaminase deficiency, (B) Humoral immunity is predominantly affected, (C) Child should receive double dose of all vaccines, (D) Patients with SCID have normal thymus
Answer is A. SCID: It is due to adenosine deaminase deficiency SCID- combined antibody and cellular defect Live vaccines are contraindicated in SCID Patients with SCID have very small thymus; tonsils & adenoids are also absent or underdeveloped