All are features in Treacher-collin syndrome except:: (A) Coloboma of inferior lid, (B) Mandibular hypoplasia, (C) Low intelligence, (D) Cleft palate
Answer is C. Intelligence is not affected in Treacher-Collin syndrome(like Turners syndrome) Treacher-Collins syndrome/Franceschetti syndrome Autosomal dominant Facial appearance: downward sloping palpebral fissures, colobomas and drooping of the lower eyelids, sunken cheekbones, deformed pinnae, atypical hair growth extending towards cheeks Facial clefts, malformed ears, deafness Hypoplastic mandible Ref: Nelson textbook of pediatrics 21st edition Pgno: 1917