Hemorrhagic cystitis is caused by: (A) Cyclophosphamide, (B) 6 mercaptounrine, (C) 5 flurouracil, (D) Busulfan
Answer is A. Refer Katzung 11/e p500 It is a prodrug and is activated BBy hepatic biotransformation to aldophosphamade. One of the degradation products is acrolein that is responsible for hemorrhagic cystitis