A scientist Dr. Gobind was asked to paicipate in a research project on myocardial infarctions in a rabbit model. Which of the following occurs in ischemic cell injury?: (A) Efflux of K+ and Na+, (B) Influx of K+ and Ca++, (C) Influx of K+ and H 2O, (D) Influx of Na+ and Ca++
Answer is D. Ischemia leads to less ATP formation and therefore increased entry of sodium and calcium ions inside the cell.