All of the following are true about the stationary phase used in high-pressure liquid chromatography, EXCEPT: (A) Made up of fine paicles, (B) Provides high resistance, (C) Provides more surface area, (D) Provides low resolution
Answer is D. Stationary phase in HPLC is made up of fine silicone paicles - option a is correct As there are a lot of fine paicles, the surface area is increased and resistance to the mobile phase is increased. That is why we apply high-pressure - option b and c are correct As the surface area is high, the chance interaction between stationary and mobile phase is high - good separation is achieved, i.e. resolution is high, not low - option d is wrong