Howell jolly bodies are seen in?: (A) Iron deficiency anemia, (B) Hemolytic anemia, (C) Polycythemia vera, (D) Multiple myeloma
Answer is B. Ans. is 'b' i.e. Hemolytic anemia Howell-Jolly bodies (HJ bodies)* These are round solid staining, dark-blue to purple inclusions. They are nuclear remanants predominatly composed of DNA.* The presence of Howel-Jolly bodies is associated with hemolytic anemia, megaloblastic anemia, hereditary spherocytosis, myelodysplastic syndrome, post splenectomy and after physiological atrophy of spleen.* Although HJ bodies are seen in all these conditions, they are most common after splenectomy.