Which of the following is the most likely inheritance pattern in the pedigree given below?: (A) Autosomal dominant, (B) Mitochondrial, (C) Autosomal recessive, (D) X-linked dominant
Answer is D. d. X-linked dominant(Ref: Nelson's 20/e p 593, Ghai 8/e p 641)It is an X-linked dominant pattern of inheritance, all the female offsprings of a diseased male (XY) receive abnormal X chromosome & express the disease, whereas none of the male offsprings of diseased father have the disease.