Which of the enzyme of glycolysis is used in gluconeogenesis?: (A) Glucokinase, (B) PFK, (C) Pyruvate kinase, (D) Phosphohexose isomerase
Answer is D. Step 2 of Glycolysis Glucose-6-phosphate is isomerised to fructose-6phosphate by phosphohexose isomerase. This is readily reversible. Since reversal of this reaction occurs in gluconeogenesisRef: DM Vasudevan, 7th edition, page no: 109