All of the following antihistaminic agents lack anticholinergic property, except:: (A) Promethazine, (B) Astemizole, (C) Levo-cetrizine, (D) Loratidine
Answer is A. All the drugs listed in the question are second generation anti-histaminic agents, except promethazine.
Anticholinergic action: Many H1 blockers in addition antagonize the muscarinic actions of Ach. The antimuscarinic action can be graded as: