First dose hypotension is caused by :: (A) Prazosin, (B) Clonidine, (C) Sodium nitroprusside, (D) Propranolol
Answer is A. Ans. is 'a' Prazosin Prazosin is a highly selective alpha1 blocker*It dilates arterioles more than veins*It is effective orally *It causes first dose hypotension *It is primarily used as an antihypertensiveIts initial dose should be low