HLA associated with rhaumatoid ahritis: (A) HLA-B27, (B) HLA-DR4, (C) HLA-CW6, (D) HLA-B8
Answer is B. HLA-DR4 (DR4) is an HLA-DR serotype that recognizes the DRB1*04 gene products. The DR4 serogroup is large and has a number of moderate frequency alleles spread over large regions of the worldDR4 is associated with extraaicularrheumatoid ahritis, hydralazine-induced female systemic lupus erythematosus, pemphigoid gestationis, pemphigus foliaceus, obstructive hyperophic cardiomyopathy, IgA nephropathy, 'shared syndrome'-systemic sclerosis/rheumatoid ahritis and polymyalgia rheumatica