Which of the following statements about oral anti-coagulants is FALSE: (A) They interfere with an early step in the synthesis of clotting factors, (B) Irrespective of the dose administered, their anticoagulant effect has a latency of onset of 1-3 days, (C) Their dose is adjusted by repeated measurement of prothrombin time, (D) They are contraindicated during pregnancy
Answer is A. Oral anticoagulants inhibit the activation of factor II, VII, IX and X. These do not affect the synthesis of these factors