Raised unconjugated hyperbilirubinemia is seen in:: (A) Gilbe's Syndrome, (B) Dubin Johnson syndrome, (C) Drug induced cholestasis, (D) Hepatocellular necrosis
Answer is A. Gilbe's syndrome- mild unconjugated hyperbilirubinemia, normal values for standard hepatic biochemical tests and normal hepatic histology other than a modest increase of lipofuscin pigment in some patients. Serum bilirubin concentrations are most often < 3 mg/dL. Extra edge : Crigler-Najjar syndrome I is often lethal, although Crigler-Najjar syndrome II is compatible with life and often presents with extreme jaundice and neurologic defects secondary to kernicterus. Both DubinJohnson syndrome and Rotor syndrome cause conjugated hyperbilirubinemia