Tadalafil acts on Phosphodiesterase 5 and causes accumulation of-: (A) cAMP, (B) cGMP, (C) PAF, (D) IL10
Answer is B. Ans. is 'b'i.e., cGMP o Inhibition of PDE-5 prevents degradation of cGMP which results in accumulation of cGMP and marked potentiation of NO action - Relaxation of smooth muscle in corpus cavemosum and blood vessels supplying it - Erection of penis,o Drugs are : -SiledenafilTodafilVardenafil