False about RANK - Ligand is :: (A) It is secreted from osteoblasts, (B) Acts on RANK receptor present on osteoclasts, (C) Denosumab is the monoclonal antibody that inhibits RANK - ligand, (D) RANK-L inhibits osteoclasts and inhibits osteoporosis
Answer is D. RANK - L acts on RANK - receptors presents on osteoclasts and activates them and stimulates bone resorption. Denosumab inhibits RANK - Ligand and prevent bone resorption.