Most sensitive investigation for preoperative localization of abnormal parathyroid glands is: (A) Neck ultrasound, (B) (99mTc) labelled Sestamibi isotope scan, (C) CT scan, (D) MRI
Answer is B. Neck ultrasound locates glands in approximately 75% of cases. (99mTc) labelled Sestamibi isotope scans identify approximately 80% of abnormal parathyroid glands.CT & MRI is not indicated prior to first-time neck exploration.