Gvnaecomastia may be associated with: (A) Klinefelter's syndrome, (B) Feminizing tumour of adrenal gland, (C) Normal adolescent boys who are rapidly virilizing, (D) All of the above
Answer is D. (D) All of the above # Pathological gynecomastia may result from deficiency of testosterone (anorchia, Klinefleter's, androgen resistance orchitis & castration); Increased production of estrogens (testicular or adrenal tumours, hCG secreting tumours> Drugs (ketoconazole, spironolactone & Cemitidine inhibit testosterone); clomiphene enhances endogenous estrogen