Kaagener syndrome is not associated with?: (A) Situs inversus, (B) Subluxation of lens, (C) Bronchiectasis, (D) Sinusitis
Answer is B. Kaagener syndrome /Immotile cilia syndrome is a AR genetic disorder that causes a defect in action of cilia . Triad includes Bronchiectasis , sinusitis and situs inversus. In males it leads to immotility of sperms causing infeility . There is also marked reduction in feility in female sufferers. There is also impaired ciliary function leading to reduced mucus clearance from lungs and susceptibility to chronic recurrent respiratory infections .