Atrial Natriuretic Peptide receptors belong to which of the following type of receptors:: (A) G-protein coupled receptors, (B) Ligand-gated guanylyl cyclase receptor, (C) Tyrosine kinase receptors, (D) JAK-STAT receptors
Answer is B. Natriuretic peptides Natriuretic peptide receptors are Transmembrane ligand-gated guanylyl cyclase receptors. ANP and BNP are selective agonist for A-type natriuretic receptor (NPR-A). CNP is selective agonist for B-type natriuretic receptor (NPR-B). The NPR-C has an extracellular domain similar to those of NPR-A and NPR-B but does not contain the guanylyl cyclase domain.