Glibenclamide reduces blood glucose in all of the following EXCEPT:: (A) Non diabetics, (B) Type 1 diabetics, (C) Type 2 diabetics, (D) Obese diabetics
Answer is B. (Ref: KDT 6/e p266) Sulfonylureas decrease blood glucose in diabetics as well as non-diabetics. It requires at least 30% of functional beta cells for their action. Insulin is the only treatment for type 1 doanetes.