Bosentan is a/an:: (A) Serotonin uptake, (B) Endothelin receptor antagonist, (C) Leukotriene modifier, (D) Phosphodiestease inhibitor
Answer is B. Endothelin receptors are of 2 types 1.ET A - in smooth muscles 2.ET B - in vascular endothelial cells BOSETAN , macicentan: endothelin receptor antagonists used for the treatment of pulmonary hypeension Ref: KD Tripathi 8th ed