metaclopromide:: (A) inhibit cholinergic smooth.muscle stimulation in the gastrointestinal tract, (B) decrease lower esophageal spinchter pressure, (C) stimulate D2 receptor, (D) enhance colonic activity
Answer is D. metaclopromide is aD2 receptor antagonist that increases cholinergic activity by inhibiting presynapyic D2 receptors in GIT . it increases LES tone that is also responsible for anti emetic action. it does not significantly increase colonic motility