In late stages of systemic sclerosis may have all the given features, EXCEPT:: (A) Pulmonary aery hypeension, (B) Interstitial lung diserase, (C) Primary biliary cirrhosis, (D) Primary sclerosing cholangitis
Answer is D. Late stages of limited systemic sclerosis patients may develop Pulmonary aerial hypeension (PAH), Interstitial lung disease, Hypothyroidism, Primary biliary cirrhosis Raynaud's phenomenon and other typical features of systemic sclerosis occur in the absence of detectable skin thickening in some patients. This syndrome is been termed SSc sine scleroderma. Ref: Harrison, E-18, P- 2757.