Which of the following drugs is useful in chronic gout but is NOT a uricosuric agent?: (A) Probenecid, (B) Lesinurad, (C) Sulfinpyrazone, (D) Allopurinol
Answer is D. Drugs used in gout are: For acute gout NSAIDs like diclofenac, indomethacin Steroids Colchicine For chronic gout Decrease formation of uric acid: Allopurinol Febuxostat Increase excretion of uric acid (uricosuric agents): Sulfinpyrazone Probenecid Benzbromarone Lesinurad Increase metabolism of uric acid: Rasburicase Pegloticase