Hypokalemic Hypeension is a feature of?: (A) Bater syndrome, (B) Gitelman syndrome, (C) Grave's disease, (D) Liddle syndrome
Answer is D. Liddle syndrome: Is a defect in aldosterone receptor ENaC which exhibits a reduced degradation and results in channel being in open configuration for a longer duration. This enhances mineralocoicoid action and leads to enhanced urinary loss of potassium. Choice A and B have normal to low BP since both have salt wasting. Grave's will cause hypeension due to intrinsic sympathomimetic action of thyroid hormones. However there is no electrolyte imbalance.