A patient presented with fever, cervical lymphadenopathy and night sweats four weeks after unprotected sexual contact. Next investigation: (A) p24, (B) ELISA, (C) CD4, (D) HIV PCR
Answer is A. Ref: PubMed* This is a possible suspicion of HIV infection.* p24 antigen is a viral protein that makes up most of the viral core.* Serum concentrations of p24 antigen are high in the first few weeks after infection; tests sensitive to p24 antigen are therefore useful for diagnosing very early infection when antibody levels are still low.