Which of the following causes 'no-reflow' phenomenon in acute myocardial infarction contributing to reperfusion injury?: (A) Myocyte hypercontracture:, (B) Leucocyte aggregation, (C) Free radicals, (D) Complement activation
Answer is B. Factors that contribute to reperfusion injury in myocardial infarction include the following: Mitochondrial dysfunction Myocyte hypercontracture Free radicals Platelet and complement activation Leukocyte aggregation - may occlude the microvasculature and contribute to the "no-reflow" phenomenon.