Recent marker for Downs syndrome is: (A) HCG, (B) Alpha fetoprotein, (C) Inhibin, (D) Estriol
Answer is C. Inhibin A is a protein secreted by the ovary, and is designed to inhibit the production of the hormone FSH by the pituitary gland. The level of inhibin A is increased in the blood of mothers of fetuses with Down syndrome. Reference: GHAI Essential pediatrics, 8th edition