Which of the following drugs is contraindicated in a patient with raised intracranial pressure?: (A) Thiopentone, (B) Propofol, (C) Midazolam, (D) Ketamine
Answer is D. Cerebral blood flow, metabolism, oxygen consumption and ICT all are increased by ketamine - ketamine is contraindicated in raised ICT.(Refer: stoelting's pharmacology and physiology in anaesthetic practice, 5th edition, pg no.186-193)