Nitric oxide synthase:: (A) Is inhibited by Ca++, (B) Catalyze a de oxygenase reaction, (C) Accept electron from NADH., (D) Requires NADPH FAD, FMN, Heme iron.
Answer is D. Ans. D. Requires NADPH FAD, FMN, Heme ironNitric oxide synthase is a very complex cytosolic enzyme which requires five redox co-factors: NADPH, FAD, FMN, Heme and tetrahydrobiopterin (FH4 ). NOS activity depends on increased conc, of Ca2++ ions.