All of following cause intravascular hemolysis, except-: (A) Mismatched blood transfusion, (B) Paroxysmal cold hemoglobinuria, (C) Thermal bums, (D) Hereditary spherocytosis
Answer is D. Ans. is 'd' i.e., Hereditary spherocytosis Hemoglobinopathies including thalassemia cause extravascularhemolysis and not intravascular hemolysis.||Causes of intravascular hemolysiso Blood transfusiony ABO mismatched transfusiony Infected bloodo Thermal bumso Snake biteso Sepsisy Bacterial/parasitic infections y Clostridial sepsisy Malariay Bartonellosisy Mycoplasma pneumoniao Mechanical heart valveso Paroxysmal hemoglobinuriay PNHy PCHCauses of extravascular hemolysiso Blood and viral infectionsy Malariay Mycoplasma pneumoniaey Infectious mononucleosiso Drua-inducedhemolvsisy G6PD/GSH deficiencyy Autoimmune drug reactionsy Strong oxidant drugs/chemicaio Autoimmune hemolvsisy Warm-reacting (IgG) AIHAy Cold-reacting (IgM) AIHAo Hemoslobinopathiesy Thalassemiao Membrane structural defecty Hereditary sperocytosisy Hereditary spherocytosisy Acanthocytosiso Environmental disordersy Malignancy/DICy TTP/HUSy Eclampsia or Preechlampsia