Bronchocentric granulomatosis commonly occurs due to?: (A) Hypersensitivity reaction to Aspergillus, (B) Immunological reaction to HIV, (C) Damage by c- ANCA, (D) Damage by p-ANCA
Answer is A. Bronchocentric Granulomatosis is characterized by peri-bronchial necrotising granulomatous inflammation. It occurs due to: Hypersensitivity reaction to Aspergillus in patients with asthma. In patients without asthma, rheumatoid ahritis and infections like TB are associated. Immunological reaction to HIV virus leads to lymphocytic interstitial pneumonitis.