Drug of choice for drug induced parkinsonism?: (A) Levodopa, (B) Anticholinergic, (C) Selegiline, (D) Carbidopa
Answer is B. Ans is 'b' i.e., Anticholinergic "Central anticholinergics are the only drugs effective in drug induced parkinsonism." o They act by reducing unbalanced cholinergic activity in the striatum of parkinsonism patients. Generally, tremor is benifited more than rigidity; hypokinesia is affected the least (Levodopa resolves hypokinesia and rigidity first and later tremor). Trihexyphenidyl (benzhexol) is the most commonly used anticholinergic in parkinsonism.