Vitamin required for bone formation as well as coagulation cascade is:: (A) A, (B) D, (C) E, (D) K
Answer is D. Vitamin K is the cofactor for g-carboxylation of glutamate residues of protein to produce g-carboxy glutamate (gla). This process is known as Vitamin K epoxide cycle. Clotting factors contain 4 to 6 g-carboxyglutamate residues:- Eg- II VII IX X Protein C Protein S Protein Z Osteocalcin Transthyretin (Prealbumin)