A four year old boy was admitted with a history of abdominal pain and fever for two months maculopapular rash for ten days, and dry cough, dyspnea and wheezing for three days. One examination liver and spleen were enlarged 4 cm and 3 cm respectively below the costal margins. His hemoglobin was 10.0 g/dl, platele count 37 x 109/L and total leukocyte count 70 x 109 /L, which included 80% eosinophils Bone marrow examination revealed a cellular marrow comprising of 45% blasts and 34% Eosinophils and eosinophilic precursors. The blasts stained negative for myeloperoxidase and non-specific esterase and were positive for
 CD19, CD 10, CD22 and CD20. Which one of the following is the most likely diagnosis?: (A) Biphenotypic acute leukemia (lymphoid and eosinophil lineage), (B) Acute eosinophilic leukemia, (C) Acute lymphoblastic leukemia with hyper-eosinophilic syndrome, (D) Acute myeloid leukemia with cosinophilia
Answer is C. None