FFP not used in ?: (A) TTP, (B) Factor XII deficiency, (C) Vitamin K deficiency, (D) Antithrombin III deficiency
Answer is B. Ans. is 'b' i.e., Factor XII deficiencyFresh frozen plasma (FFP)FFP is defined as the fluid poion of human blood that has been centrifuged, separated, and frozen solid at -18degc within 6 hours.FFP contains stable coagulation factors and plasma proteins :(i) Fibrinogen (iii) Albumin & Immunoglobulin(v) Factor II, V, VII, IX, X, XI(ii) Antithrombin(iv) Protein C, S.Indications for the use of FFP are : ?Deficiencies of factor II, V, VII, IX, X and XI when specific component therapy is neither available nor appropriate.Emergency reversal of warfarin effect.In vit K deficiency as replacement for Vit K dependent factors (II, VII, IX, X)Antithrombin III deficiencyAfter massive blood transfusion.In immunodeficiency as a source of immunoglobulinTTP