Familial hypercholesterolemia is due to defect in: (A) Apo A, (B) Lipoprotein lipase, (C) Apo C, (D) Apo B 100
Answer is D. Name Defect Remarks Familial hypercholesterolemia (type IIa) Defective LDL receptors or mutation in the ligand region of apo B-100 Elevated LDL levels and hypercholesterolemia, resulting in atherosclerosis and coronary disease Reference: Harper; 30th edition; Page no: 275