Which of the following agents is recommended as first line drug for treatment of gastrointestinal stromal tumors (GIST)?: (A) Sorafenib, (B) Geftinib, (C) Imatinib, (D) Erlotinib
Answer is C. Imatinib is drug of choice for GIST. Imatinib resistant cases can be treated with sunitinib. Tumors resistant to both imatinib and sunitinib are treated with regorafenib.