All of the following are true about Metoclopramide except: (A) It is an antiemetic which blocks 5HT3 receptors, (B) It has prokinetic action by 5HT4 agonism, (C) It has D2 blocking action resulting in extrapyramidal side effects, (D) It can be used for L - Dopa induced vomiting
Answer is D. Metoclopramide crosses blood brain barrier & because of D2 blocking action can reduce the efficacy of L-Dopa. Therefore can not be used in L-Dopa induced vomiting.