Which of the following produces neuropsychiatric symptom?: (A) Cycloserine, (B) Cyclosporine, (C) Cephalosporine, (D) Ethambutol
Answer is A. Cycloserine is an antibiotic effective against Mycobacterium tuberculosis. The side effects are mainly central nervous system (CNS) manifestations, i.e. headache, irritability, depression, psychosis and convulsions. Co-administration of pyridoxine can reduce the incidence of some of the CNS side effects (e.g. convulsions).