A girl with mild von willebrand disease has a previous history of heavy bleeding during tooth extraction. What is the prophylaxis to be given before tooth extraction?: (A) Desmopressin, (B) Blood transfusion, (C) Fresh frozen plasma, (D) Cryoprecipitate
Answer is A. In patients of von Willebrand disease, DDAVP can be given intra-nasally 2 hours before a procedure like dental extraction- mild to moderate risk of bleeding and can be repeated 12-24 hours. Aminocaproic acid or Tranexamic acid is an impoant therapy either alone or in an adjunctive capacity paicularly for the prevention or treatment of mucosal bleeding.