The primary action of leptin is:: (A) To increase food intake, (B) To decrease food intake, (C) To increase gastric contraction, (D) To increase intestinal motility
Answer is B. LEPTIN It is a 167 aa peptide secreted from adipocytes, blood leptin level reflects total body fat. Its primary action: To decrease food intake. It in CNS decreases NPY and alpha MSH. Leptin deficiency may lead to obesity. Ref: Sleisenger and Fordtran's, Edition-9, Page-8.