Spironolactone should not be given with: (A) Chlohiazide, (B) Beta blockers, (C) ACE inhibitors, (D) Amlodipine
Answer is C. Sprinolanctone is a potassium sparing diurectic It doesn't excrete potassium - increasing potassium levels in the blood ACE IN. also increases potassium levels in the blood Hence the combination is contraindicated Ref: KD Tripathi 8th ed