Digoxin toxicity is aggrevated by: (A) Hypokalemia, (B) Hyperkalemia, (C) Hypermagnesimaia, (D) Hypocalcemia
Answer is A. Hypokalemia is usually observed with chronic toxicity or in patients taking diuretics; it reduces the rate of Na+/K+ ATPase pump turnover and exacerbates pump inhibition due to digitalis. Hyperkalemia is the usual electrolyte abnormality precipitated by digoxin toxicity, primarily in the acute setting Refer kDT 6/e p499