Which of the following is the most common clinical manifestation of Rosai Dorfman disease?: (A) Tender, red plaques and nodules together with areas of erythema, (B) Painless cervical lymphadenopathy, (C) Noncicatricial alopecia, (D) Recurrent staphylococcal skin infections.
Answer is B. Rosai Dorfman disease: Massive cervical lymphadenopathy, usually bilateral and painless, is the most common manifestation. It is generally a benign disorder in spite of its propensity to form large masses and to disseminate to both nodal and extranodal sites.