Invasion of perineural space is a feature of: (A) Pleomorphic adenoma, (B) Wahin's tumor, (C) Mucoepidermoid carcinoma, (D) Adenoid cystic carcinoma
Answer is D. Adenoid cystic carcinoma Most common location -Parotid & submandibular glands are M/E - Small cells having dark, compact nuclei & scant cytoplasm. Pattern : Tubular, solid, or cribriform patterns reminiscent of cylindromas arising in adnexa of skin Slow growing, adenoid cystic carcinomas are unpredictable tumors with tendency to invade perineural spaces & are stubbornly recurrent.