25/M presented with jaundice, clay coloured stool and pruritus. Bilirubin was 7gm%, Direct Bilirubin 5gm%, ALP 500 IU/L. Biopsy from biliary tract revealed the following. What is your diagnosis?: (A) PSC, (B) SBC, (C) PBC, (D) Bile duct stones
Answer is A. Ans. (a) PSC* Clinical feature of jaundice, clay coloured stool and pruritus is suggestive of obstructive jaundice. Biopsy showing fibrotic obliteration of bile ducts ("onionskin" fibrosis) seen in primary biliary cirrhosis.