Which among the following is a Transcription inhibitor?: (A) Chloramphenicol, (B) Streptomycin, (C) Puromycin, (D) Amanitin
Answer is D. The inhibitors of transcription and its action is very impoant in the entrance exams. Rifampicin: bind beta subunit of polymerase Actinomycin D: inhibit elongation of RNA strands by inhibiting RNA polymerase Streptoglydin Heparin Alpha-Amanitin blocks the translocation of RNA polymerase during transcription Ref: Harper, 27th Edition, Page 351