All are disorders due to peroxisomal abnormalities except?: (A) Pfeiffer syndrome, (B) Zellweger syndrome, (C) Hyperoxaluria type 1, (D) Acatalasemia
Answer is A. Peroxisome is an organelle involved in the metabolism of many molecules including fatty acids, purines and amino acids. It is bounded by a single membrane and contains more than 50 enzymes. Pfeiffer syndrome is due to mutations in the gene encoding fibroblast growth factor receptor 1 (FGR1). It is a craniosynostosis syndrome.