All are true about digoxin except:: (A) Causes bradycardia due to increased vagal tone, (B) Acts by inhibiting Na+K+ ATPase in myocardial fibres, (C) It is 95% plasma protein bound, (D) Primarily excreted unchanged by glomerular filtration
Answer is C. Ans. (C) It is 95% plasma protein bound(Ref: KDT 8th/e p559)Plasma protein binding of digitoxin is high (95%) whereas it is low (70-80%) for digoxin.