Most Severe degree of alkalosis occurs in obstruction of -: (A) Cardiac end, (B) Pylorus, (C) Ileocaecal region, (D) Colon
Answer is B. • Gastric alkalosis is most marked with vomiting due to pyloric stenosis or obstruction because the vomitus is acidic gastric juice only.
• Vomiting in other conditions may involve a mixture of acid gastric loss and alkaline duodenal contents and the acid-base situation that results is more variable.
• Loss of alkaline small intestinal contents can even result in an acidosis if gastric acid secretion is suppressed.