True about G-protein receptor complex: (A) It interacts transmembrane domain, (B) GTP to GDP, (C) Adenyl cyclase activation leads to increased cAMP, (D) GPCR has no phosphorylation propey
Answer is A. G protein-coupled receptors (GPCRs) which are also known as seven-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein-linked receptors (GPLR), constitute a large protein family of receptors, that sense molecules outside the cell and activate inside signal transduction pathways and, ultimately, cellular responses.Coupling with G proteins, they are called seven-transmembrane receptors because they pass through the cell membrane seven times.