The following is a pro-apoptic factor: (A) Bax, (B) Bcl-2, (C) Bcl-xL, (D) Mci-1
Answer is A. Ans. (a) Bax (Ref: Robbins 9th/pg 55; 8th/pg 28)Proapoptotic: Apafl, cytochrome c, Bak, Bax, Bim, AIF, P53, Caspases, CD95 (FAS), TNF R1 and Smac/DiabloAntiapoptotic: Bcl2,BclxL ,Bclx ,FLIP,McL-1,IAP