GnRh analogues are used in: (A) Ovulation induction, (B) Endometriosis, (C) Fibroid, (D) All of the above
Answer is D. GnRh includes both agonists and antagonists. Used for ovulation induction, fibroid and endometriosis . It induces a state of pseudo menopause were there is a deficiency of both estrogen and progesterone so that fuher growth of fibroid and endometriosis does not occur. To overcome the distressing s/e of menopause E+P are added which is called as "Add Back" regime. Other condition in which they are used is true precocious pubey in which there is activation of HPO axis .