The following drug acts as Rho- kinase(ROCK enzyme) inhibitor: (A) Trimetazidine, (B) Fasudil, (C) Pinacidil, (D) Ranolazine
Answer is B. Fasudil is the Rho kinase inhibitor. Rock enzyme produce vasoconstriction and increase oxygen demand which is blocked by fasudil decreasing the myocardial oxygen demand