A patient was treated with amitriptyline for depression, developed urinary retention, constipation & blurring of vision. The most likely cause is -: (A) Symptoms of depression persisting, (B) Anticholinergic side effects, (C) Depression medicamentosa, (D) Any of above
Answer is B. Amitriptyline and other TCAs produce anticholinergic side effects which are manifested as dry mouth (↓ salivation) blurred vision, urinary retention, constipation, decreased sweating.