Thymic hypoplasia is seen in: (A) Digeorge syndrome, (B) Common variable immunodeficiency, (C) Ataxia telengiectasia, (D) All
Answer is D. Ans. d (all). (Ref. Robbin's Patho, 6th - 173, 235, 691)Thymic abnormalities are classically described with DiGeorge syndrome, but hypoplasia of thymus can also be seen in ataxia telengiectasia and common variable immunodeficiency.Third and fourth pouch syndrome or DiGeorge fs syndrome or CATCH syndrome# Cardiac anomalies,# Absent thymus,# T cell deficiency,# Coarse dysmorphic facial features and# Hypocalcemic tetany.