Sister Mary Joseph nodule is most commonly seen with: March 2011: (A) Ovarian cancer, (B) Stomach cancer, (C) Colon cancer, (D) Pancreatic cancer
Answer is B. Ans. B: Stomach cancer Gastric tumour may spread the abdominal cavity to the umbilicus (Sister Joseph's nodule) Sister May Joseph's nodule: Periumbilical nodule/ hard mass Represents metastatin involvement of the paraumbilical nodes from intrapelvic or intraabdominal malignancies Seen with: - Stomach - Large bowel - Ovary - Pancreatic tumour Indicates poor prognosis