Heberden's Arthropathy affects -: (A) Lumbar spine, (B) Symmetrically large joints, (C) Sacroiliac joints, (D) Distal interphalangeal joints
Answer is D. In osteoarthritis of hand :

i)   Distal interphalangeal joint :- Heberden's node.
ii)  Proximal interphalangeal joint :- Bouchard's node