The presence of a noncompetitive inhibitor can be implicated in which of the outcome?: (A) Leads to both an increase in the Vmax of a reaction and an increase in the Km, (B) Leads to a decrease in the observed Vmax, (C) Leads to a decrease in Km and Vmax, (D) Leads to an increase in Km without affecting Vmax
Answer is B. In the presence of a noncompetitive inhibitor, Vmax is decreased, whereas Km is unchanged. The steady-state concentration of ES is decreased.