A 1 cm x 1 cm squamous cell carcinoma of anal canal is best treated initially by: (A) Abdominoperineal resection, (B) Localized resection followed by irradiation, (C) Proximal colostomy followed by interstitial irradiation, (D) Chemo-radiotherapy
Answer is D. Anal cancer: #Treatment is by chemoradiotherapy in the first instance # Associated with HPV # More prevalent in patients with HIV infection # May affect the anal verge or anal canal # Lymphatic spread is to the inguinal lymph nodes # Uncommon tumour, which is usually a squamous cell carcinoma # Major ablative surgery is required if the above fails Ref: Bailey & Love&;s Sho Practice of Surgery,E25,Page-1269