A female has hypopigmented lesion on centre of forehead. Drug responsible is ?: (A) Hydroquinone, (B) Ether metabolite of hydroquinone, (C) Para teiary butyl catechol, (D) Para teiary butylphenol
Answer is D. Hypo or amelanotic lesions simulating vitiligo can be caused by various chemicals at the site of contact. eg: parateiary butylphenol paraphenylenediamine-hairdye monobenzylether of hydroquinone derivative of hydroquinone present in skin lightening creams coicosteroids rubber-gloves,aprons,tape,slippers monobenzyl ether of hydroquinone-leather IADVL textbook of dermatology , pigmentary disorders 745