In pregnancy with increased MSAFP which of the following should be done?: (A) Repeat measurement of MSAFP at later date, (B) USG, (C) Amniocentesis, (D) Termination of pregnancy
Answer is B. Maternal Serum Alpha Fetoprotein (MSAFP) estimation at 16 weeks was used as a screening method for open neural tube defects but today,has been almost completely replaced by ultrasonography. Refer page no 486 of Text book of obstetrics,sheila balakrishnan,2 nd edition.