Super antigen acts through?: (A) IL-3, (B) IL-6, (C) IFN-Gamma, (D) IL_1 & TNF
Answer is D. Superantigens are ceain protein molecules such as staphylococcal enterotoxin, that stimulate large numbers of T cells irrespective of antigenic specificity. This leads to an excessive and dysregulated immune response with release of cytokines such as interleukin-1,2 and tumor necrosis factor and interferon gamma. Reference : Anathanarayan & paniker's 9th edition, pg no:90,203 <\p>