Patient diagnosed as squamous cell intraepithelial lesion which of the following has the highest risk for progression to carcinoma;: (A) Low grade squamous intraepithelial neoplasia, (B) High grade squamous intraepithelial neoplasia, (C) Squamous intraepithelial associated with HPV 16, (D) Squamous intraepithelial neoplasia associated with HIV
Answer is B. High grade squamous intraepithelial lesion have a propensity to progress and become invasive, therefore need investigations and treatment Ref: Shaw Gynecology 17 e pg 410.