Duration of action of flumazenil is:: (A) 5 minute, (B) 10 minute, (C) 20 minute, (D) 1-2 hours
Answer is D. Flumazenil is absorbed orally ;oral bioavailability is ~16% but its not used orally .On I.v .injection ,action of flumazenil stas in seconds &last for 1-2 hours ;elimination t1/2 is 1 hour due to rapid metabolism. REF: KD Tripathi 8th ed.