In peripheral tissues which of the following contains substance P: (A) Plasma cell, (B) Mast cell, (C) Nerve terminal, (D) Vascular endothelium
Answer is C. Substance P (SP) is an undecapeptide (a peptide composed of a chain of 11 amino acid residues) member of the tachykinin neuropeptide family. It is a neuropeptide, acting as a neurotransmitter and as a neuromodulator. Ref guyton and hall textbook of medical physiology 12/e pg 83