30 year old woman's PAP smear is given below. What is your next approach: (A) Continue routine screeing, (B) Advice loop electro excisional procedure, (C) Hysterectomy, (D) Cryotherapy
Answer is B. The pap smear shows:
→ Dysplastic squamous cells
→ High N:C ratio
→ Irregular nuclear membrane
→ Coarse chromatin
All these suggest high-grade squamous intraepithelial lesion (HSIL)