Mikulicz cell and Russell bodies are characteristic of:: (A) Rhinoscleroma, (B) Rhinosporidiosis, (C) Lupus vulgaris, (D) Lethal midline granuloma
Answer is A. (a) Rhinoscleroma(Ref. Scott Brown, 6th ed., 4/8/34)Definitive diagnostic test of rhinoscleroma is biopsyBiopsy in rhinoscleroma shows granulomas with plasma cells containing Russell bodies and large macrophages containing the phagocytosed bacteria are known as Mikulicz cells.