Isolated deletion of which chromosome causes Myelodysplastic syndrome ?: (A) 2q, (B) 5q, (C) 8q, (D) 11q
Answer is B. Both primary and t- MDS are associated with recurrent chromosomal abnormalities including monosomies 5 and 7, deletions of 5q, 7q, and 20q and trisomy 8. Ref : Robbins and Cotran Pathologic basis of disease.South Asia Edition volume 1.page no. 614,615