Chromosomal instability syndrome is: (A) Fanconi syndrome, (B) Ataxia Telangectasia, (C) Bloom syndrome, (D) All of the above
Answer is D. Immunohistochemistry : Used in diagnosis of abnormal cells such as those found in tumors also used to understand the distribution and localization of biomarkers and differentially expressed protiens in different parts of a biological tissue.
Southern blotting : Used to detect DNA changes, e.g. whether genes have been deleted or rearranged. It is also used to detect RFLP. So it can detect gene expression.
Northern blotting : Used to detect RNA level. So used to analyze pattern and level of gene expression in different tissue.
Microarray : Can detect genomic changes as it measures many mRNA levels at once.