Pentostatin acts by inhibiting:: (A) RNA dependent DNA polymerase, (B) Aldolase, (C) Adenosine deaminase, (D) Adenylyl cyclase
Answer is C. * Pentostatin and cilastatin are not statins i.e. these do not act by inhibiting HMG-CoA reductase. * Pentostatin acts by inhibiting adenosine deaminase. * It is used for the treatment of hairy cell leukemia. * Drug of choice for hairy cell leukemia is cladribine.