Mechanism of action of Pemetrexed is:-: (A) RNA synthesis inhibitor, (B) Dihydrofolate reductase inhibitor, (C) Dopamine agonist, (D) Topoisomerase inhibitor
Answer is B. Dihydrofolate reductase Inhibitors Methotrexate Pralatrexate Pemetrexed PEMETREXED - used in mesothelioma D: Topoisomerase introduces negative coil's and aids in replication IRINOTECAN - topoisomerase Inhibitor