The following drug acts by blocking reverse transcriptase: (A) Zidovudine, (B) Acyclovir, (C) Amantadine, (D) Ribavirin
Answer is A. Zidovudine acts by inhibiting the conversion of RNA to DNA by blocking the enzyme reverse transcriptase. It is a prodrug which has to be conveed to triphosphate form to be active Baveja 5th ed Pg.: 519