In Promyelocytic Leukemia, all of the following are features, except:: (A) Retinoic acid is used in treatment, (B) 15/17 translocation maybe seen, (C) CD 15/34 both seen in same cell, (D) Associated with Disseminated Intravascular Coagulation (DIVC)
Answer is C. CD 15 and CD 34 are not associated with Promyelocytic leukemia (PML). CD 15 is present on most Reed-Sternberg cells, associated with hodgkins lymphoma. CD 34 are seen in alveolar soft tissue sarcoma, pre B-ALL, AML, AML-M7, meningiomas, neurofibromas, schwannomas, and papillary thyroid carcinoma. Ref: Harrison's Principles of Internal Medicine, 17th Edition, Page 678-682; Harrison 16th Edition, Page 7632-634; Bobbin's 7th Edition, Page 693; Davidson's Principles and Practice of Medicine, 20th Edition, Chapter 24, Page 1047.