All of the following statement are true regarding asbestosis except:: (A) Amphiboles are more pathogenic, (B) It begins in a upper zone, (C) Can cause mesothelioma, (D) Pulmonary hypeension may be seen
Answer is B. Asbestosis exists in 2 diff forms: - 1. Amphibole - it is straight fiber - goes directly into lungs 2. Chrysotile - Serpentile Appearance - gets trap in upper airway Asbestosis is heavy paicle, therefore disease begins with the base of the lung. Mesothelioma is most specific Carcinoma associated with asbestosis M/C Ca associated - Bronchogenic Ca Initial manifestation - Pleural plaques then fibrosis