All of the following are centrally acting antihypeensive drugs except:-: (A) Alpha methyl dopa, (B) Clonidine, (C) Guanabenz, (D) Trimethoprim
Answer is D. Stimulation of a2 receptors in CNS leads to decrease in sympathetic outflow Therefore, a2 agonists can decrease the sympathetic activity and are useful for the treatment of hypeension. These include: Clonidine a-methyl dopa Guanafacine Guanabenz