CO acts by inhibiting which component of respiratory chain: (A) Cytochrome B, (B) Cytochrome C oxidase, (C) NADH CoQ reductase, (D) Oxidative phosphorylation
Answer is B. Carbon monoxide is toxic for mitochondria in man, altering the mitochondrial respiratory chain at the cytochrome c oxidase level. This inhibition in cytochrome c oxidase may play a role in the development of the symptoms observed in acute CO poisoning, and in some diseases related to smoking