Which of the following is the most potent glucocoicoid: March 2010: (A) Hydrocoisone, (B) Prednisolone, (C) Betamethasone, (D) Triamcinolone
Answer is C. Ans. C: Betamethasone Betamethasone and dexamethasone are very potent and highly selective glucocoicoids. Long acting, causes marked pituitary-adrenal suppression, but fluid retention and hypeension is not a problem. Hence they are preferred in situations in which fluid retention must be avoided like cerebral edema.