Acute disseminated encephalomyelitis (ADEM) is a white matter disease that is indistinguishable from multiple sclerosis by all except: (A) Monophasic, (B) Rapidly lethal, (C) Associated with brainstem and spinal cord disease, (D) Associated with MRI  lesions which may resolve
Answer is A. ADEM is a demyelinating disease of the brain ,brainstem and spinal cord that is indistinguishable from MS on MRI. However,it is monophasic,  that is  it occurs acutely on a single occasion and not in a recurrent fashion like MS.