All are markers of Wilms' tumor except:: (A) Desmin, (B) Vimentin, (C) TTF 1, (D) Cytokeratin
Answer is C. Wilms tumor Marker of Triphasic tumor. 3 components d/t abnormal mesenchymal differentiation : Blastemal Epithelial Stromal Various markers: Desmin - Muscle cell tumor Vimentin - Mesenchymal cell tumor marker Cytokeratin - Epithelial cell tumor marker TTF-1 (thyroid transcription factor): Lung cancer Thyroid cancer. Adenocarcinoma Small cell Ca of lung.