A commonest side effect of Dapsone is :: (A) Hemolytic anemia, (B) Thrombocytopenia, (C) Cyanosis, (D) Bone marrow depression
Answer is A. Hemolysis develops in almost every individual treated with 200-300 mg dapsone per day. Doses of less than 100 mg in healthy persons and less than 50 mg per day in persons with G-6PD deficiency do not cause hemolysis. Methemoglobinemia is also very common.