The drug prednisolone is known to be a powerful anti- inflammatory agent. This is true due to the action of the drug on which of the following enzymes?: (A) Cyclo oxygenase, (B) Lipoxygenase, (C) Phospholipase A, (D) Phosphodiesterase
Answer is C. -Steroids inhibit phospholipase A2 enzyme by causing induction of proteins called Annexins. -Phospholipase A2 is involved in formation of PG (Prostaglandin) and LT(leukotriene)