Which of the following drugs does not cross blood placental barrier?: (A) Atropine, (B) Glycopyrrolate, (C) Physostigmime, (D) Hyoscine hydro bromide
Answer is B. Ans. (B) Glycopyrrolate(Ref: KDT 8th/e p124)Glycopyrrolate is a quarternary ammonium compounds and is thus water soluble and unable to penetrate BBB.