Which of the following immunosuppressants is not used for the treatment of cancers?: (A) Cyclophosphamide, (B) Cyclosporine, (C) Methotrexate, (D) 6-Mercaptopurine
Answer is B. (Ref: KDT 6/e p839, 840) All antimetabolites can be used as anticancer drugs except azathioprine. Cyclosporine acts by inhibiting the transcription of IL-2 gene. It has no anti-cancer propey.