Hyperammonemia type I is due to deficiency of: (A) CPS-I, (B) CPS-II, (C) Arginase, (D) Arginosuccinase
Answer is A. Deficiency of any of the urea cycle enzymes result in hyperammonemia. Carbamoyl phosphate synthetase1 deficiency or hyperammonemia type 1 is comparatively rare and is characterized by severe hyperammonemia.Ref: DM Vasudevan - Textbook of Biochemistry, 7th edition, page no: 205