Not a specific tumor marker is?: (A) CD 99, (B) HMB45, (C) b- globulin, (D) CEA
Answer is D. Ans is 'd' i.e., CEA o Carcinoembryonic antigen (CEA) is used as tumor marker for colorectal cancer (major use), lung cancer, breast cancer and ovarian cancer. It is alsoincreased in non-neoplastic conditions like alcoholic cirrhosis, hepatitis, IBD (CD, UC), smoking and pancreatitis.o CEA lacks sensitivity as well as specificity, hence cannot be used to confirm the diagnosis.About other optionso CD 99 - specific marker for Ewing's sarcomao HMB 45 - specific marker for malignant melanomao b- globulin - specific marker for multiple myeloma