Essential fructosuria is due to the deficiency of which enzyme?: (A) Aldolase A, (B) Aldolase B, (C) Fructokinase, (D) Glucokinase
Answer is C. Ans. (c) FructokinaseRef: Harper, pg. 169"Deficiencies in the enzymes of fructose and galactose metabolism lead to essential fructosuria and galactosemias""Lack of hepatic fructokinase causes essential fructosuria, and absence of hepatic aldolase B, which cleaves fructose 1-phosphate,leads to hereditary fructose intolerance"Metabolism of fructose. Aldolase A is found in all tissues, whereas aldolase B is the predominant form in liver. (not found in liver)