CAPLACIZUMAB is used for treatment of?: (A) Acquired Thrombotic Thrombocytopenic Purpura (aTTP), (B) Plaque Psoriasis, (C) Breast cancer, (D) Bladder cancer
Answer is A. CAPLACIZUMAB: a. It is a Von - Willebrand factor (vWF) directed antibody fragment b. Target the A1 - domain of vWF, and inhibits the interaction between vWF and platelets, thereby reducing both vWF - mediated platelet adhesion and platelet consumption. c. Used for treatment of acquired Thrombotic Thrombocytopenic Purpura (aTTP)