Neostigmine antagonizes non-depolarizing blockade by all of the following mechanisms EXCEPT: (A) Decreasing the breakdown of acetylcholine at the motor end plate, (B) Preventing the K+ efflux from the cell, (C) Increasing the release of acetylcholine at the motor end plate, (D) Depolarization at the motor end plate
Answer is B. Neostigmine, sold under the brand name Prostigmin among others, is a medication used to treat myasthenia gravis, Ogilvie syndrome, and urinary retention without the presence of a blockage. It is also used together with atropine to end the effects of neuromuscular blocking medication of the non-depolarizing type.