The most common site of metastasis in neuroblastoma?: (A) Lung, (B) Liver, (C) Lymph nodes, (D) Veebrae
Answer is C. Metastatic spread, which is more common in children older than 1 yr of age at diagnosis, occurs local invasion or distant hematogenous or lymphatic routes. The most common sites of metastasis are the regional or distant lymph nodes, long bones and skull, bone marrow, liver, and skin. Lung and brain metastases are rare, occurring in >3% of cases. Reference: Nelson; Neuroblastoma; Page no: 2461