Gene for folate carrier protein located on ?: (A) Chromosome 10, (B) Chromosome 5, (C) Chromosome 21, (D) Chromosome 9
Answer is C. Chromosome 21 [Ref: www.ihop netorgiunipub/ihopigi92248.htmll Transpo of folate compounds Folk acid transpo * Chromosome location ----> 21 q 223. * Gene name --> SLCI9AI solute carrier family 19 (folate transpoer), member * Gene product/function --> Transpoer for the iniake of folate. Transpo of folate occurs by novel mechanism called potocytosis which functionally couples three components namely the folate receptor, the folate transpoer and v-type h+ pump. * Alleles _> A 80G single nucleotide polymorphism