Local anesthetics are typically injected or applied very close to their intended site of action. From which of the following routes absorption of local anaesthetic is maximum?: (A) Intercostal, (B) Epidural, (C) Brachial, (D) Caudal
Answer is A. The rate of systemic absorption is propoionate to the vascularity of the site of injection: intravenous > tracheal > intercostal > caudal > paracervical > epidural > brachial plexus > sciatic > subcutaneous. Ref: Morgan, Jr. G.E., Mikhail M.S., Murray M.J. (2006). Chapter 14. Local Anesthetics. In G.E. Morgan, Jr., M.S. Mikhail, M.J. Murray (Eds), Clinical Anesthesiology, 4e.