Drug of choice for pregnant female suspected of having a baby with congenital adrenal hyperplasia is: (A) Dexamethasone, (B) Betamethasone, (C) Hydrocoisone, (D) Predinsolone
Answer is A. Dexamethasone is very potent and highly selective glucocoicoid to be staed before 10 weeks of gestation to suppress fetal androgen production effectively It has a long duration of action and cause marked pituitary-adrenal suppression. DOC for CAH is hydrocoisone but DOC for pregnant women having baby with CAH - dexamethasone REF.Essential of medical pharmacology K D TRIPATHI 6 Edition, Page No - 283