Effacement of foot process of nephron is seen in?: (A) Minimal change disease, (B) Focal segmental glomerulosclerosis, (C) Acute glomerulonephritis, (D) Membranous nephropathy
Answer is A. * Minimal change renal disease is the most common form of idiopathic nephrotic syndrome in children of age group 2 to 6 years. It accounts for around 85% of cases and are mostly steroid sensitive.* The finding in renal biopsy in light microscope is usually normal. Electron microscope shows effacement of epithelial foot process.* Other most commonly asked question in nephrotic syndrome is the indication for renal biopsy -# Age group less than 1 and more than 10 years# Steroid resistant nephrotic syndrome# Steroid dependent nephrotic syndrome# Nephritic onset nephrotic syndrome# Persistent hematuria and hypo complement levels more than 2 months# Before starting cyclosporine analog drugs.