A 14 year old boy with difficulty in walking and behavioural disturbance, recovered from prolonged jaundice recently, has bluish pigmentation over lunula. The next investigation to be done:: (A) Nail fold cappillaroscopy, (B) Slit lamp examination, (C) Biopsy of the pigmented area, (D) Ankle-brachial pressure index
Answer is B. Neurological involvement + Jaundice + Azure Nails (Bluish discoloration of nails) = Wilson's disease Dx: Slit lamp examination and 24 hrs urinary copper Rx: for Neurological feature - Tetrathiomolybdate