Indomethacin causes:: (A) Closure of ductus in premature neonate, (B) Patent ductus arteriosus, (C) Closure of ductus in term & premature neonates, (D) Closure of ductus in older children also
Answer is A. a. Closure of ductus in premature neonate(Ref: Nelson's 20/e p 2197)Indomethacin, a Prostaglandin inhibitor is used in medical closure of Ductus arteriosus in preterm neonates with PDA.