Which of the following antiparkinsonian drugs directly activates dopaminergic D2 receptors in the striatum?: (A) Pramipexole, (B) Entacapone, (C) Benserazide, (D) Selegiline
Answer is A. (Ref: KDT 6/e p419, 420) Directly acting D2 receptor agonists can be Ergot derivatives e.g. bromocriptine and pergolid Non-ergot compounds e.g. pramipexole and ropinirole