Not true about clofazamine -: (A) Used in DLE, (B) Causes ichthyosis and hyperpigmentation, (C) Interferes DNA synthesis, (D) Used in lepra reaction
Answer is A. Ans. is 'a' i.e., Used in DLE Clofazimineo Clofazimine is a leprostatic drug.o It acts by interfering the template function of DNA.o Adverse effects of clofazimine Skin - Reddish-black discolouration of skin, dryness of skin and itching, Discolouration of hair and body secretions, acneform eruptions and phototoxicity, conjuctival pigmentation. GIT- Enteritis with loose stools, nausea, abdominal pain, anorexia and weight loss.Remember - Clofazimine has antiinflammatory property can be used in lepra reaction.