Alkanization of urine is done for:: (A) Weak acid drugs, (B) Weak basics drugs, (C) Strong acidic drugs, (D) Strong basic drugs
Answer is A. Elimination of some drugs is by altering the pH Eg; alkalinization for weak acidic drugs, e.g. Barbiturates acidification of weak alkaline drugs or weak bases weak acids or weak bases- unionized forms- difficult to get eliminated strong acids and strong bases- ionized forms- could be eliminated easily Ref: KD Tripathi pharmacology 7th edition (page.no: 81)