Which of the following tumor is associated with BRAF mutation?: (A) Adenocarcinoma Colon, (B) Medullary thyroid carcinoma, (C) Hodgkin's lymphoma, (D) Hepatocellular carcinoma
Answer is A. Tumors associated with BRAF mutation are: Melanoma Adenocarcinoma of colon Papillary thyroid carcinoma Hairy cell leukemia Langerhans cell histiocytosis - BRAF inhibitors Debrafenib ,vemurafenib have demonstrated efficacy in patients with lung cancer harboring BRAF mutations