Sugamadex is used for ?: (A) Organophosphate poisoning, (B) Reversal of NM blockers, (C) Treatment of local anaesthetic poisoning, (D) Treatment of central anticholinergic syndrome
Answer is B. Ans. is 'b' i.e., Reversal of NM blockers Sugamadex is a novel reversing agent developed for terminating the action of nondepolarizing muscle relaxants rocuronium and vecuronium. It is a modified y-cyclodextrin with high affinity for recuronium and vecuronium. It encapsulates one molecule of NM blocker within its molecule forming an inactive chelate which is excreted in urine with VA of 2 hours. Its side effects are mild precordial pain, nausea, alteration of taste and rarely allergy.