All of the following are true about Irinotecan except: (A) It is a Topo-isomerase II inhibitor, (B) It is excreted though liver, (C) It is used for colorectal cancer, (D) It can cause diarrhoea because of cholinergic property
Answer is A. Irinotecan & Topotecan are Topoisomerase-I inhibitors.
Etoposide & Teniposide are Topoisomerase-II inhibitors.