Most specific indicator of liver injury?: (A) ALT, (B) AST, (C) SAP, (D) 5' nucleotidase
Answer is A. Most specific indicator of liver injury is: ALT: SGPT (product present in cytosol that come in blood due to injury) AST: SGOT, present in cardiac tissue/liver so it's not specific SAP: (Cholestasis marker) Do not indicate hepatocyte necrosis 5' nucleotidase: Cholestasis marker