Acute fatty liver of pregnancy is seen usually in?: (A) 3rd trimester, (B) 1st trimester, (C) Immediate postpaum, (D) Intrapaum
Answer is A. Acute fatty liver almost always manifests late in pregnancy with a mean gestational age of 37 weeks-- Mostly primigravida and also more in multifetal gestation Clinical features Persistent nausea and vomiting malaise, anorexia epigastric pain progressive jaundice Pre ecclampsia hypofibrinogenemia hypoalbuminemia hypocholesterolemia prolonged clotting times.