Uronic acid pathway is not involved in:: (A) Conjugation of bilirubin, (B) GAG synthesis, (C) Vitamin C synthesis, (D) Biotransformation
Answer is C. Ans. C. Vitamin C synthesis(Ref: Harper 31/e page 186)Glucuronic acid is involved in the conjugation of Bilirubin.Uronic acid and amino sugar are the repeating disaccharide unit in the glycosamino glycans.Glucuronidation is a Phase II Xenobiotic reactions (Biotransformation)Uronic acid pathway cannot synthesize vitamin C in humans and higher primates because of lack of L-Gulano lactone oxidase