Spironolactone is contraindicated with which of the following drugs:: (A) Enalapril., (B) Atenolol., (C) Verapamil., (D) Chlorthiazide.
Answer is A. Spironolactone is a K+ sparing diuretic. It should be used cautiously if the patient is receiving K+ salts or drugs increasing serum K+ levels.

ACE inhibitors can also cause hyperkalemia as an adverse effect. If these are combined with K+ sparing diuretics, cardiac arrhythmia due to high serum K+ levels may develop