Which drug is excreted unchanged in urine ?: (A) Verapamil, (B) Furosemide, (C) Propranolol, (D) Thiopentone
Answer is B. Ans. is 'b' i.e., Furosemide Furosemide pharmacokinetics Furosemide is rapidly absorbed orally but bioavailability is about 60%. Lipid solubility is low and it is highly bound to plasma proteins. It is pay conjugated by glucuronic acid and is mainly excreted unchanged by glomerular filtration and tubular secretion.