Tmreatment of hormone dependent fungating carcinoma of breasyt with secondaries in lung is: (A) Simple mastectomy and oophoroctomy, (B) Radical mastectomy and oophoroctomy, (C) Adrenalectomy, (D) Lumpectomy followed by castration
Answer is A. Hormonal therapy in Carcinoma in breast Ovarian suppression or ablation Bilateral oophorectomy. Medically by LHRH agonist (Goserelin, leuprolide) SERM: Tamoxifen and Raloxifen Aromatase Inhibitors Non-steroidal : Letrozole & Anastrazole Steroidal : Exmestane Anti-Estrogens Fulvestrant Progestins Megesterol & Medroxyprogesterone acetate Ref: schwaz's principle of surgery 10th edition Pgno : 552-553