Lactic acidosis is a side effect of:: (A) Phenformin, (B) Metformin, (C) Chlorpropramide, (D) Glibenclamide
Answer is A. Ans. is 'a' i.e. Phenformin Both, phenformin and metformin cause lactic acidosis but phenformin more than metforminOther important adverse effects of oral hypoglycemicsHypersensitivityRashesPhotosensitivityAgranulocytosisChloe static jaundice (Only by chlorpropamide)Disulfiram like effect - ChlorpropamideNot safe in pregnancy (Sulfonylureas), secreted in milk.