Mitochondrial DNA (mt-DNA) is known for all except:: (A) Maternal inheritance, (B) Heteroplasmy, (C) Leber hereditary optic neuropathy is the prototype, (D) Nemaline myopathy results due to mutations in mt- DNA
Answer is D. Nemaline myopathy Autosomal recessive Heterogeneous condition and not a mitochondrial disease. Myopathy d/t 5 genes . All code for thin filament-associated proteins, suggesting disturbed assembly or interplay of these structures as a pivotal mechanism. Mutations of the nebulin (NEB) gene Severe neonatal and early childhood forms