Disseminated intravascular coagulation (DIC) is characterized by the following except: (A) Widespread bleeding\/thrombosis, (B) Prolongation of prothrombin time\/paial thromboplastin time, (C) High levels of fibrin degradation products, (D) High platelet count
Answer is D. DIC is characterised by bleeding & organ damage due to ischemia caused by the effect of widespread intravascular thrombosis. Platelet count is reduced due to platelet aggregation & adhesion as a result of endothelial injury. Prothrombin time & activated paial thromboplastin time are prolonged due to reduced fibrinogen. Fibrinogen is reduced due to consumption in microvascular coagulation. Fibrin degradation products are raised due to secondary fibrinolysis.Reference :Harsh mohan textbook of pathology sixth edition pg no 338.