Metformin is NOT effective in lowering of blood sugar level in which of the following patients?: (A) Non diabetics, (B) Obese diabetics, (C) Type 2 diabetics, (D) Diabetics not responding to sulfonylureas
Answer is A. (Ref:KDT 6/e p269) Metformin is the drug of choice for the treatment of obese diabetic patients, as it causes weight loss. It does not cause release of insulin, therefore less chances of hypoglycemia.