Which of the following sources of cholesterol is most impoant for sustaining adrenal steroidogenesis when it occurs at a high rate for a long time?: (A) De novo synthesis of cholesterol from acetate, (B) Cholesterol in LDL paicles, (C) Cholesterol in the plasma membrane, (D) Cholesterol in lipid droplets within adrenal coical cells
Answer is B. Cholesterol esters in LDL are the most impoant source of cholesterol for sustaining adrenal steroidogenesis when it occurs at a high rate over a long me. This cholesterol can be used directly after release from LDL and not stored. De novo synthesis of cholesterol from acetate is a minor source of cholesterol in humans.