Which of the following is not true about mycophenalate mofetil -: (A) Prodrug of mycophenolic acid, (B) Can be used with calcineurin inhibitor and glucocoicoid, (C) Cannot be used with Azathioprine, (D) Is nephrotoxic
Answer is D. Ans. is 'd' i.e., Is nephrotoxic o Nephrotoxicity is not an adverse effect of mycophenolate mofetil. o It is a prodrug of mycophenolic acid. o It is used as an 'add on' therapy to cyclosporine (calcineurin inhibitor) + glucocoicoids in renal transplantation. o It should not be used with azathioprine as both the drugs act by inhibiting purine synthesis.