The following factors shift the oxygen dissociation curve to the right, except: (A) Hypoxia, (B) Acidosis, (C) Increase in 2, 3-DPG, (D) Alkalosis
Answer is D. Oxygen saturation curve Physiology A curve that describes the relationship between Hb O2 saturation and tension; defined by a sigmoid curve which reflects the interaction of the 4 Hb molecules involved in O2 uptake, transpo and release; a &;right shift&; of the curve indicates | Hb affinity for O2, as occurs in | pH-ie,acidosis, | temperature, | PCO2, while a &;left shift&; indicates | O2 affinity with | pH, | temperature, | 2,3 DPG and | PCO2Right shifts Acidosis, hypehermia, alveolar hypoventilation, anemia Left shifts Alkalosis, hypothermia, hyperventilation,carboxyhemoglobinemia, hypophosphatemia, | fetal Hb.Ganong&;s Review of Medical Physiology; 24th edition; page no:642