Which anticancer drug causes hypercoagulable syndrome?: (A) 5-FU, (B) L-asparaginase, (C) Melphalan, (D) Carmustine
Answer is B. Hypersensitivity reaction manifested by fever, chills, nausea, and vomiting, uicaria, bronchospasm, respiratory failure and hypotension; i ed risk of both clotting and bleeding as a result of alterations in various clotting factors; pancreatitis, and neurological toxicity. Ref: KD Tripathi 8th ed.