All are true about Sodium nitroprusside except: (A) It acts on endothelium to produce Nitric Oxide, (B) Drug of choice for Hypertensive emergency, (C) It is both arterial & veno-dillator, (D) It can cause hypothyroidism
Answer is B. Sodium nitroprusside is used as a second line treatment for Hypertensive emergency (DOC is Nicardipine).
It is a mixed vasodilator which acts on endothelium to release Nitric oxide (NO).
It is metabolized by liver to produce thiocyanate and may cause hypothyroidism.