A premature infant is born with a patent ductus aeriosus. Its closure can be stimulated by administration of: (A) Prostaglandin analogue, (B) Estrogen, (C) Anti-estrogen compounds, (D) Prostaglandin inhibitors
Answer is D. Before 2 weeks of gestation indomethacin 0.2mg/kg dose orally every 12-24 hr for 3 doses. Ref : Ghai essential pediatrics,eighth edition P.no: 419