Villous pattern is lost in: (A) Hydatidiform mole, (B) Invasive mole, (C) Tubal mole, (D) Choriocarcinoma
Answer is D. Choriocarcinoma : On histopathology , it is composed of cells of early cytotrophoblast and synctiotrophoblast There are no villi Has ability to metastatic Most common mode of spread is hematogenous Ref: Dutta Obs 9e pg 187.