A child presents with Hepatosplenomegaly, Abdominal distension, Jaundice, Anemia and Adrenal calcification. Which of the following is the Diagnosis ?: (A) Adrenal hemorrhage, (B) Wolman's disease, (C) Pheochromocytoma, (D) Addison's disaease
Answer is B. Wolman disease is a congenital disease characterized by an impaired metabolism of the fats (lipids). It is the most severe type of lysosomal acid lipase deficiency. The lysomal acid lipase deficiency causes a buildup of lipids (fats) in body organs and calcium deposits in the adrenal glands. Reference: GHAI Essential pediatrics, 8th edition