The pathognomonic sign of neurofibromatosis is: (A) Cafe-au-lait macules, (B) Axillary frekling, (C) Shagreen patch, (D) None of the above
Answer is B. B i.e. Axillary freckling Neurofibromatosis is autosomal dominantQ disorder. Axillary freckling (crowe sign) is a pathognomic sign of von- Reckling hausen's type 1 neurofibromatosisQ. Cafe - au - lait macules alone are not absolutely diagnostic of NF1, regardless of their size and number.