The antimicrobial agent which inhibits the ergosterol biosynthesis is: (A) Ketaconazole, (B) Amphotercin B, (C) 5-flucytosine, (D) Grisefulvin
Answer is A. Refer KDT 6/e 761 Azoles act by inhibiting an enzyme, lanosterol -14-alpha -demethylase. This enzyme is involved in formation of ergosterol Amphotercin B acts6by binding to ergosterol and forming pores in fungal cell membrane