Which among the following used as a pre-anaesthetic medication causes the longest amnesia?: (A) Diazepam, (B) Lorazepam, (C) Midazolam, (D) Flunitrazepam
Answer is B. The longest amnesia is produced by lorazepam although half-life of lorazepam (15 hours) is shoer than diazepam (36 hours) and this is probably because of its strong receptor binding potential.