Which Vitamin is required for carboxylation of clotting factors?: (A) Vitamin A, (B) Vitamin D, (C) Vitamin E, (D) Vitamin K
Answer is D. Ans. D. Vitamin K(Ref: Harper 31/e page 529-533)Vitamin K is required for the post-translational carboxylation of glutamic acid (Gamma Carboxylation), which is necessary for calcium binding to g carboxylated proteins.