Drug useful in hepatic encephalopathy is:: (A) Magnesium sulphate, (B) Lactulose, (C) Bisacodyl, (D) Biphosphonates
Answer is B. Ans. (B) Lactulose(Ref: KDT 8th/e p725)Lactulose is a laxative that acts by conversion to short chain fatty acids in the colon.These fatty acids result in decrease in pH of intestinal juice.At low pH, ammonia becomes ionized (NH4+ ) and thus cannot be absorbed.