Which of the following estimates blood creatinine level most accurately: (A) Jaffe method, (B) Kinetic jaffe method, (C) Technicon method, (D) Enzyme assay
Answer is D. D i.e. Enzyme assay Gas chromatography - isotope dilution mass spectrometry (GC- IDMS) is considered the method of choice for establishing the true concentration of creatinine in serum because of its excellent specificity > HPLC > Enzyme assay > Alkaline picrate methodsQ.