Zileuton is a: (A) 5 lipooxygenase inhibitor, (B) TXA2 inhibitor, (C) Leukoteriene receptor antagonist, (D) Prostaglandin synthesis inhibitor
Answer is A. Zileuton is an orally active inhibitor of 5-lipoxygenase, and thus inhibits leukotrienes (LTB4, LTC4, LTD4, and LTE4) formation, used for the maintenance treatment of asthma. Ref: KD Tripathi 8th ed