Which among the following tumor is associated with Polycythemia vera?: (A) Osteosarcoma, (B) Ovarian tumor, (C) Cerebellar haemangioblastoma, (D) Pitutary adenoma
Answer is C. Tumors associated with polycythemia vera are Hypernephroma, Hepatoma, Cerebellar hemangioblastoma, Uterine myoma, Adrenal tumors, Meningioma, Pheochromocytoma. The JAK2 gene located on the sho arm of chromosome 9 and loss of heterozygosity on chromosome 9p due to mitotic recombination is the most common cytogenetic abnormality in Polycythemia Vera. Ref: Harrison's Internal Medicine, 18th Edition, Pages 898-900