Vascular dermal necrosis is seen with: (A) Warfarin, (B) Hirudin, (C) Dabigatran, (D) Rivaroxiban
Answer is A. Vascular dermal necrosis occurs due to warfarin Cutaneous necrosis with reduced activity of protein C sometimes occurs during the first weeks of therapy. Rarely, the same process causes frank infarction of the breast, fatty tissues, intestine, and extremitiesKatzung 12e pg: 610