Hyperplastic aeriolitis with necrotizing aeriolitisis seen in?: (A) Wegner's granulomatosis, (B) Benign hypeension, (C) Buerger's disease, (D) Malignant hypeension
Answer is D. Hyperplastic aeriolosclerosis is more typical of severe hypeension. Vessels exhibit "onion skin" ."concentric, laminated thickening of aeriolar walls and luminal narrowing . The lamination consists of smooth muscle cells and thickened , re duplicated basement membrane . In malignant hypeension these changes are accompnied by fibrinoid deposits and vessels wall necrosis . Prominent in kidney Robbins 9th edition page no. 334