All of the following are good prognostic factors for childhood ALL except-: (A) Female sex, (B) Hyperdiploidy, (C) t(12:21) translocation, (D) Pre B cell ALL
Answer is A. Favorable prognostic marker for ALL includes Age between 2 and 10 years A low white cell cout Hyperdiploidy Trisomy of chromosomes 4,7,10 Presence of a t (12;21) seen in pre B cell ALL Reference : Robbins and Cotran Pathologic basis of disease.South Asia Edition volume 1.page no. 592