A 37 yr old man was reffered to NIMHANS Neurology opd with history of 2 episodes of GTCS, Headache, weakness on right side of body,behavior and personality changes. NCCT was given below what is the most probable diagnosis can be made?: (A) Meningioma, (B) Oligodendroglioma, (C) Glioblastoma, (D) Craniopharyngioma
Answer is B. Oligodendroglioma has chicken wire calcifications. Above given NCCT image shows ill-defined hypodense lesion in left frontal lobe with dense foci of calcification in the centre. * Both low- and high-grade oligodendroglial tumors express proangiogenic mitogens and may contain regions of increased vascular density with finely branching capillaries that have a 'chicken wire' appearance. Up to 90% of oligodendrogliomas contain visible calcification on CT, which can be central, peripheral or ribbon-like. Meningioma is dural based and appear hyperdense on NCCT. Craniopharyngioma is supra-stellar in location. GBM usually doesn't show calcification.