Which one of the following is true of hyaline membrane disease of the newborn -: (A) Prematurity provides relative protection of the occurrence, (B) Maternal steroid exposure increase severity of the disease, (C) Phosphatidyl glycerol estimation is a reliable method of diagnosis, (D) Surfactant increases the surface tension of a lveoli
Answer is C. Ans. is 'c' i.e., Phosphatidyl glycerol estimation is a reliable method of diagnosis o In HMD surfactant is reduced and its measurement can be used for diagnosis e.g. in shake test. o Constituent of surfactant are - dipalmitoyl phosphatidylcholine (lecithin), phosphatidylglycerol, apoproteins (surfactant proteins ----> SPA, SPB, SPC, SPD) and cholesterol.