Which of following anti-gout drugs act by inhibiting the enzyme xanthine oxidase?: (A) Probenecid, (B) Rasburicase, (C) Allopurinol, (D) Sulfinpyrazone
Answer is C. DRUGS USED IN CHRONIC GOUT Group Mechanism Drugs Uric acid synthesis inhibitors Xanthine oxidase inhibitors Allopurinol, Febuxostat Uricosuric agents URAT-1 transpoer inhibitors Probenecid, Sulfinpyrazone, Benzbromarone, Lesinurad Recombinant uricase Cause oxidation of urate to allantoin Rasburicase, Pegloticase