Drugs causing aplastic anaemia include:: (A) Chlorpromazine, (B) Allopurinol, (C) Diclofenac, (D) All of the above
Answer is D. Common drugs & toxins implicated in etiology of aplastic anemia: Drugs Chemicals A. Dose-dependent action - Cytotoxic drugs Benzene B. Idiosyncratic action Insecticides (Organophosphates, organochlorine) Antibacterials (Sulphonamides, Chloramphenicol) Pentachlorophenol (an antibacterial, fungicide & wood-preservative) Anti-inflammatory drugs (Phenylbutazone, Indomethacin, piroxicam, Diclofenac, Naproxen) Antirheumatics (Gold, penicillamine) Antiepileptics (Phenytoin, Carbamazepine) Antithyroids Tranquilizers (Chlorpromazine) Others-Furosemide, Allopurinol