The peripheral blood smear of a patient shows features of thalasemia, also presented with anaemia. Family history is also +ve. The investigation done to establish the diagnosis is :: (A) ESR estimation, (B) Blood spherocyte estimation, (C) Bone marrow aspiration, (D) Hb-electrophoresis
Answer is D. Ans. is 'd' i.e. Hb- electrophoresisElectrophoretic techniques are used for routine hemoglobin analysis. It helps in quantification and identification of various hemoglobins.As we all are aware that thalassemia is a quantitative defect in Hb characterized by lack of certain types of hemoglobin and compensatory increase in other hemoglobin, therefore electrophoresis proves to be a reliable method for screening in thalassemia.