G6PD is enzyme of:: (A) Mitochondria, (B) Cell membrane, (C) Golgi organ, (D) Endoplasmic reticulum
Answer is B. Ans. (b) Cell membraneRef: Lippincotts Biochemistry 6th ed. P 151-152* G6PD enzyme is located at the cell membrane. RBC membrane is one such example, and is associated with severe pathology* Location: X chromosome at q28 locus. (G6PD enzyme is X-linked gene)* It protects the RBC from the deleterious effects of oxidizing agents by reducing themselves to NADPH.* In deficiency of G6PD enzyme - impaired ability of RBC to form NADPH - Hemolysis