Which of the following malignancy is predominantly associated with osteoblastic metastasis?: (A) Renal cell carcinoma, (B) Breast carcinoma, (C) Prostate carcinoma, (D) Thyroid carcinoma
Answer is C. Osteoblastic metastasis are seen in prostate carcinoma. Also know: Other malignancies associated with osteoblastic metastasis are breast carcinoma, Hodgkin's lymphoma, carcinoids and medulloblastomas. Purely osteolytic metastasis commonly arise from carcinoma of lung, kidney, thyroid and lymphoma. Ref: Differential Diagnosis in Conventional Radiology By Francis A. Burgener, 3rd edn, page 110