True about CF-: (A) Incidence is 1:2000, (B) Positive Sweat test, (C) Mutation in CFTR gene, (D) May presents as meconium ileus
Answer is B. A positive sweat chloride test indicates that it is likely that the infant or person tested has cystic fibrosis (CF). Positive sweat chloride tests are typically repeated for verification. The results may also be confirmed by CF gene mutation panel testing. Ref Harrison20th edition pg 288