Which of following is the most common antecedent infection associated with Guillain-Barre syndrome-: (A) Mycoplasma, (B) Epstein-Barr virus, (C) Chlamydia infection, (D) Campylobacter jejuni
Answer is D. Ans. is 'd' i.e., Campylobacter jejunio Campylobacter ieiuni enteritis has emerged as the most common antecedent infection in patients with Guillain- Barre syndrome in recent years.# "In the last few years, Campylobacter jejuni enteritis has been identified as the most common antecedent infection in patients with Guillain-Barre syndrome, occurring in about 30% "o Antecedent infections common with G.B.S.o Antecedent infections are thought to trigger the immune response that leads to acute polyneuropathy,o Approximately 2/3rdpatients gives history of antecedent respiratory or gastrointestinal tract infection.o Campylobacter infection most commonly identified (implicated in 30% cases)Other common infections are :# Cytomegalovirus# Epstein Barr virus# Mycoplasma pneumonial# Influenza like illnessA samll percentage of patient develop GBS after triggering events such as :# Immunisation# Surgery# Trauma# Bone marrow transplantation