t(15;19) translocation is associated with:: (A) Chronic myelogenous leukemia, (B) Chronic neutrophilic leukemia, (C) Chronic eosinophilic leukemia, (D) Essential thrombocytosis
Answer is B. CML is due to the balanced translocation between chromosomes 9 and 22 . Chronic neutrophilic leukemia is associated with a t(15;19) translocation. Chronic eosinophilic leukemia has deletion or balanced translocations of PDGFR gene. Ref: Harrison, Edition-18, Page-898