Which of the following toxins will produce the condition shown below?: (A) Leukocidin, (B) TSST-1, (C) ETA and ETB, (D) Serum opacity factor
Answer is C. STAPHYLOCOCCAL SCALDED SKIN SYNDROME Induced by epidermolytic exotoxins (exfoliatin) A and B, which are released by S. aureus -detachment within the epidermal layer, by breaking down the desmosomes. Exotoxins cleave desmoglein-1, which holds the granulosum and spinosum layers together, similar to the pathophysiology of the autoimmune skin disease 'pemphigus vulgaris.'