In metabolism of xenobiotics, all of the following reactions occur in phase one except:: (A) Oxidation, (B) Reduction, (C) Conjugation, (D) Hydrolysis
Answer is C. Metabolic reactions may be classified into phase I (non-synthetic) and phase II (synthetic) reactions. Phase I reactions include oxidation, reduction, hydrolysis, cyclization and decylization etc. whereas phase II reactions include glucuronidation, acetylation,methylation, sulfation and glycine conjugation etc.