Fructose intolerance is due to deficiency of: (A) Aldolase B, (B) F ructokinase, (C) Triokinase, (D) Aldolase A
Answer is A. Fructose intolerance is due to deficiency of aldolase-B.Incidence out of 1 is 20,000.It is an autosomal recessive inborn error of metabolism.Fructose-1-phosphate cannot be metabolized.Accumulation of fructose -1-phosphate will inhibit glycogen phosphorylase.Ref: DM Vasudevan, 7th edition, page no: 144