Main cytokine involved in erythema nodosum leprosum reaction is: (A) IL 2, (B) Interferon gamma, (C) Tumour necrosis factor alpha, (D) Macrophage colony stimulating factor
Answer is C. Erythema nodosum leprosum rection is type II lepra rection .In this modules over skin are seen This is a type III hypersensitivity reaction . Main cytokine involve is TNF -alpha DOC - gluco-coicoids