All agents have been used in drug regimens for the treatment of breast carcinoma. Which one has specific activity in a subset of female breast cancers?: (A) Anastrozole, (B) Doxorubicin, (C) Fluoxymesterone, (D) Trastuzumab
Answer is D. Trastuzumab Each of the drugs listed has been used in drug regimens for breast cancer, but only trastuzumab has specificity in its actions. The drug is a monoclonal antibody to a surface protein in breast cancer cells that over express the HER2 protein. Consequently, trastuzumab has value in a specific subset of breast cancers.