Multi-drug resistance tuberculosis implies resistance to at least -: (A) Any two antitubercular drugs, (B) Isoniazid and ethambutol, (C) Rifampicin and ethambutol, (D) Isoniazid and rifampicin
Answer is D. Multidrug-resistant TB is defined by resistance to atleast rifampicin & isoniazid, with or without other drug resistance . Extensively drug resistant TB is defined as resistance to atleast rifampicin & isoniazid in addition to any quinolone & atleast one injectable second -line agent. Reference: Harrison20th edition pg 1056