The distribution of keratins (K) in the basal layers is:: (A) K5/K14, (B) K1/K10, (C) K2/K11, (D) K6/K16
Answer is A. Basal layer has keratin types K5/K14 Keratin Heterodimer Sites K 5/14 Stratum basale - If defective- Epidermolysis Bullosa simplex K 1/10 Stratum Spinosum K 2/11 Stratum Granulosum K 3/12 Cornea - If defective - Corneal dystrophy K 4/13 Buccal mucosa K 6/16 Nails K 8/18 Liver - If defective - Liver cirrhosis