Major source of collagen in cirrhosis -: (A) Kupfer cells, (B) Ito cell (Hepatic stellate cell), (C) Hepatocyte, (D) Canalicular cell
Answer is B. Ans. is 'b' i.e., Ito cell (Hepatic stellate cell)o Perisinusoidal stellate cells (Ito cells) play a role in the storage and metabolism of vitamin A and are transformed into collegen producing myofibroblasts when there is inflamation of the liver. These cells are the major source of collegen in cirrhosis.