Posterior polymorphous dystrophy -: (A) Causes corectopia, (B) Is inherited in an autosomal recessive fashion, (C) Causes blindness in over 90% of sufferers, (D) Can be trated with lamellar corneal grafts
Answer is A. It is a dominantly inherited dystrophy of endothelium and Descemet's membrane. It is characterised by lesions with variable appearance, such as vesicles, curvilinear lines or geographical opacities at the level of Descemet's membrane. The condition is very slowly progressive and thus usually asymptomatic. Corneal oedema sometimes may occur, requiring keratoplasty. Rarely it may be complicated by secondary glaucoma.Reference:Comprehensive ophthalmology,AK Khurana,4th edition,page no.119