Maternal disomy of chromosome 15 is seen in: (A) Prader - Willi syndrome, (B) Klinefelter's syndrome, (C) Angelman syndrome, (D) Turner's syndrome
Answer is A. Uniparental disomy occurs when both chromosomes of a pair or areas from 2 chromosome in any individual have been inherited from a single parent. Maternal uniparental disomy is seen in Leader -Willi syndrome. Paternal uniparental disomy is seen in Angelman syndrome . Reference: Nelson TB of pediatrics pg 412 19th edition.