Which one of the opioid has maximum plasma protein binding capacity:: (A) Morphine, (B) Sufentanil, (C) Fentanyl, (D) Pethidine
Answer is B. Protein binding capacity of opioids: Morphine: 30-40%., Pethidine: 70%, Fentanyl: 84%. Alfentanil: 92%., Sufentanil: 93%.