Which drug is used for topical application in respiratory papillomatosis?: (A) Acyclovir, (B) Ranitidine, (C) Cidofovir, (D) Ribavirin
Answer is C. Cidofovir Gold standard treatment for respiratory papillomatosis is Laser MLS/ Powered MLS (using microdebrider). Cidofovir is a recent drug which is used intralesionally or topically. Its active metabolite, cidofovir diphosphate, inhibits viral replication by selectively inhibiting viral DNA polymerase.