ICATIBANT IS A ?: (A) bradykinin B 1 antagonist, (B) bradykinin B 2 antagonist, (C) bradykinin B 3 antagonist, (D) histamine receptor H3 antagonist
Answer is B. Icatibant, New Bradykinin-Receptor Antagonist, in HAE Icatibant (Firazyr, Shire) synthetic selective decapeptide bradykinin B2 receptor competitive antagonist contains 5 non-natural amino acids to enhance resistance to peptidases Icatibant administered sc injection as single 30 mg peak concentration within 30 minutes, ref : kd tripathi 8th ed