All are true about Zollinger-Ellison syndrome except:: (A) Recurrent ulceration after acid reducing surgery, (B) Raised gastrin levels in all cases, (C) Decreased BAO/MAO, (D) Diarrhea
Answer is C. Ans. (c) Decreased BAO/MAOBlood levels of ZES:* 100% all patients will have Se. gastrin >100pg/ml* BAO >15meq/hr in most patients* BAO will be 60% of MAO (BAO - Basal Acid output, MAO - Maximal Acid Output)* Levels of Se. Gastrin >1000pg/ml is diagnostic* If there is only borderline elevation provocative tests with secretin, Calcium etc are done* With Secretin stimulation gastrin increases >200pg/ml in 15 minutes is diagnostic