Fastest acting antithyroid drugs ?: (A) Iodides of Na/ K, (B) Propylthiuracil, (C) Methimazole, (D) Nitrates
Answer is A. Ans. is 'a' i.e., Iodides of Na Iodine and Iodides Iodine is the fastest acting thyroid inhibitor Most impoant action is inhibition of hormone release (thyroid constipation); but all facets of thyroid synthesis may be affected. Excess iodide inhibits its own transpo in thyroid cells and may alter the redox potential of cells, thus interfering iodination - reduced T4/T3 synthesis (Wolff-chaikoff effect).