In chronic Hepatitis B infection, which one of the following markers is indicative of active viral replication and the corresponding risk of disease transmission?: (A) Hbe antigen, (B) HBs antigen, (C) Anti - Hbe, (D) Anti - HBs
Answer is A. HBeAg indicates active intrahepatic viral replication, reflecting high infectivity REF:<\p> ANATHANARAYANAN MICROBIOLOGY NINTH EDITION PAGE.547