The site of action of vasopressin antagonist in kidney: (A) Medullary Collecting duct, (B) Coical collecting duct, (C) Proximal convoluted tubule, (D) Distal convoluted tubule
Answer is A. V2 receptors are located on medullary collecting ducts. drugs acting on V2 receptor antagonists are vaptans like convivaptan and tolvaptan Ref: Goodman Gillman 12th ed pg 707