In congenital adrenal hyperplasia, deficient enzyme is - most womon: (A) 11(3 hydroxylase deficiency, (B) 21 a hydroxylase deficiency, (C) 3a hydroxylase deficiency, (D) 17a hydroxylase deficiency
Answer is B. Ans. is 'b' i.e., 21-a Hydroxylase Congenital adrenal hyperplasia (CAH) Group of AR disorder MC adrenal disorder in childhood Most common 21-hydroxylase deficiency In 21a-hyroxylese deficiency There is deficiency of mineralocoicoids & glucocoicoid. This leads to hypoglycemia, hyponatremia