Which of the following is false about lower esophageal sphincter: (A) Relaxation is mediated by VIP and nitrous oxide, (B) Resting pressure is 10 to 25 mmHg, (C) Pinch cock action of diaphragm protects against reflex, (D) Abnormal relaxation will cause achalasia
Answer is D. Relaxation will cause GERD
Failure to relax will cause achalasia