Diagnostic criteria of pure red cell aplasia (PRCA) includes all of the following, except:: (A) Severe anemia, (B) Reticulocyte count < 1%, (C) Normocellular marrow, (D) Thrombocytopenia
Answer is D. Pure red cell aplasia: Selective depletion of erythroid precursors in bone marrow with consequent severe normocytic normochromic anemia & reticulocytopenia. Diagnostic criteria for pure red cell aplasia are: Giant normoblasts in bone marrow Severe anemia Reticulocyte count < 1% Normocellular marrow with mature erythroblasts <0.5%.