Therapeutic index is a measure of?: (A) Efficacy, (B) Adverse effects, (C) Safety, (D) Potency
Answer is C. ANSWER: (C) Safety REF: KDT 7th ed p, 54/55Therapeutic index = Median lethal dose/Median effective doseOne estimate of a drug's margin of safety is the ratio LD50/ED50, the therapeutic index, which is a statement of how selective the drug is in producing its desired versus its adverse effects.