Rosenthal fibres are seen in -: (A) Pilocytic astrocytoma, (B) Glioblastoma, (C) Medulloblastoma, (D) Ependymoma
Answer is A. Rosenthal fibers are thick, elongated, "corkscrew" eosinophilic bundles that are found on H&E staining of the brain.
They are seen in the presence of long-standing gliosis, pilocytic astrocytoma, Alexander's disease (a rare leukodystrophy) and fucosidosis.