Intrauterine Infections most commonly associated with Neural tube defects is: (A) CMV and Toxoplasma, (B) Toxoplasma and Rubella, (C) Rubella and herpes, (D) CMV and herpes
Answer is B. Toxoplasmosis and rubella are most commonly associated with Neural tube defects Toxoplasmosis in fetus occurs mostly if the infection is in the later pa of the pregnancy and is associated with Neurologic abnormalities, hydrocephalous, cerebral calcification, chorioretinal scars with or with out severe visual impairment. Rubella is one of the most complete teratogens, and sequelae of fetal infection are worst during organogenesis