The cardiovascular side effect of Dexmedetomidine is following: (A) Hypotension and Bradycardia, (B) Hypeension and Tachycardia, (C) Hypotension and Tachycardia, (D) Hypeension and Bradycardia
Answer is A. Dexmetetomidine is a highly selective alpha2 - adrenoceptor against thus can cause hypotension and Bradycardia. Dexmedetomidine * Highly selective alpha - 2 adrenoreceptor agonist * Used mainly as IV adjunct during induction and /or maintenance of general anesthetics * Minimal respiratory and cardiovascular depression * Good sedation , good analgesic, sympatholytic effects * Selectivity for alpha1: alpha 2 receptors is 1:1640