Majority of patients with HNPCC have mutations in ?: (A) MSH I, (B) MSH 2, (C) MSH3, (D) MSH4
Answer is B. Ans. is 'b' i.e., MSH 2 Hereditary Nonpolyposis colorectal cancer (HNPCC) is caused by inherited mutations in genes that encode proteins responsible for the detection, excision, and repair of errors that occur during DNA replication.