Necrotizing aerioritis with fibrionoid necrosisis -: (A) Immediate hypersensitivity, (B) Cell mediated immunity, (C) Antigen-antibody complex mediated, (D) Cytotoxic cell mediated
Answer is C. Ans. is 'c' i.e., Antigen-antibody complex mediatedo The principal morphological manifestation of immune (antigen-antibody) complex injury is necrotizing vasculitis with necrosis of vessel wall and intense neutrophilic infiltration.o The necrotic tissue and deposits of immune complexes, complement and plasma proteins produce a smudgy eosinophilic deposition that obscures the underlying cellular detail, an appearance termed fibrinoid necrosis.