Methotrexate toxicity is prevented by giving?: (A) Folic acid, (B) Folinic add, (C) Citric acid, (D) Glucaric acid
Answer is B. Ans. is 'b' i.e., Folinic acid * Folinic acidFor preventing methotrexate toxicity* AllopurinolTo prevent hyperuricemia caused by rapid destruction of cells during cancer chemotherapy.* Lithium carbonateIt has stimulant effect on bone marrow, so used during myelosuppresive drug therapy.* OndensetronFor controlling cytotoxic drug induced vomiting.* MesnaFor prevention of cyclophosphamide/ formamide indused hemorrhagic cystitis