Pre conceptional intake of which of the following will decrease the incidence of neural tube defects?: (A) Folate, (B) Vitamin E, (C) Vitamin C, (D) All of the above
Answer is A. Prophylactic folic acid supplementation in  2nd and 3rd  trimester along with Vit. K in the last month of pregnancy is recommended, particularly in women receiving antiepileptic drugs to minimise neural tube defects and bleeding disorder respectively in the neonate.
Reference: Essentials of Medical Pharmacology Eighth Edition KD  TRIPATHI  page no 449