Least likely to be Pre-leukemic condition is ?: (A) Paroxysmal nocturnal hemoglobinuria, (B) Paroxysmal cold hemoglobinuria, (C) Aplastic anemia, (D) Myelodysplastc syndrome
Answer is B. Ans. is 'b' i.e., Paroxysmal cold hemoglobinuria Conditions predisposing to acute leukemia o Myelodysplastic syndrome o Chronic myeloproliferative disorders o Ionizing radiation & ceain toxic chemicals o Bloom syndrome o Fanconi anemia o Paroxysmal nocturnal hemoglobinuria o Li-Fraumani syndrome o Diamond - Blackfan anemia o Ataxia telangiectasia Down syndrome Klinefelter's syndrome o Neurofibromatosis o Aplastic anemia (rarely) Schwachman syndrome Turner syndrome