Female patient with bilateral hilar lymphadenopathy and joint pain. ACE levels are elevated. The diagnosis in this patient is: (A) Silicosis, (B) Hodgkin lymphoma, (C) Sarcoidosis, (D) Non Hodgkins lymphoma
Answer is C. Sarcoidosis is a multisystem granulomatous disorder of unknown aetiology characterised by presence of non caseating granulomas. LOFGREN SYNDROME - an acute illness characterised by erythema nodosam, peripheral ahropathy, uveitis, bilateral hilar lymphadenopathy,lethargy and fever often seen in young women. Bilateral hilar lymphadenopathy may be sometimes discovered incidentally on chest x-ray . Ref Davidson edition23rd pg 608