Classical markers for Hodgkin&;s disease is: (A) CD 15 and CD 30, (B) CD 15 and CD 22, (C) CD 15 and CD 20, (D) CD 20 and CD 30
Answer is A. <p>Reed Sternberg cells in all types of Hodgkin&;s diseases, except in lymphocytic prdominance type,express immunoreactivity for CD 15 & CD 30. RS cells in lymphocytic predominance type are negative for both CD 15 & CD 30, but positive for CD 20.</p><p>Reference : Harsh mohan textbook of pathology 6th edition pg no370</p>