Amoxycillin is better than ampicillin due to:: (A) Better biovailability if taken with food, (B) Lesser biovailability if taken with food, (C) Incidence of diarrhea is higher, (D) More active against Shigella and H. influenza
Answer is A. Amoxicillin It is a close congener of ampicillin (but not a prodrug); similar to it in all respects except: * Oral absorption is better; food does not interfere with absorption; higher and more sustained blood levels are produced. * Incidence of diarrhoea is lower. * It is less active against Shigella and H. influenzae. Many physicians now prefer it over ampicillin for bronchitis, urinary infections, SABE and gonorrhoea. ESSENTIALS OF MEDICAL PHARMACOLOGY K.D.TRIPATHI SIXTH EDITION PAGE NO:701