Duchenne&;s Muscular Dystrophy is a disease of: (A) Neuromuscular junction, (B) Sarcolemmal proteins, (C) Muscle contractile proteins, (D) Disuse atrophy due to muscle weakness
Answer is C. Duchenne and Becker muscular dystrophy are caused by loss-of-function mutations in the dystrophin gene on the X chromosome. The encoded protein, dystrophin, is a key component of the dystrophin-glycoprotein complex.Dystrophin is thought to provide mechanical stability to the myofiber and its cell membrane during muscle contraction.Robbins 9e 1242