Function of hepatic kupffer cells is: (A) Formation of sinusoids, (B) Vitamin A storage, (C) Increase blood perfusion, (D) Phagocytosis
Answer is D. Kupffer cells Kupffer cells, derived from the macrophage - monocyte system Are irregular stellate - shaped cells that also line the sinusoids, insinuating between endothelial cells Phagocytic, play a major role in the trapping of foreign substances and initiating an inflammatory response MHC-II antigens are expressed on kupffer cells but do not confer efficient antigen presentation compared with macrophages elsewhere in the body Ref: Sabiston 20th edition Pgno :1430