A patient with 37 weeks of gestation, came to hospital without antenatal check-up and presented with onset of labor. On examination, the mother is hep B positive, what management should be given to neonate?: (A) Hep b vaccine only, (B) Hep B vaccine+ IG, (C) First IG then HEP B vaccine after 1 month, (D) Only IG
Answer is B. Infants of HBsAg-positive mothers should receive Hepatitis B immune globulin (HBIG) immunoprophylaxis at bihand Hepatitis B vaccine at one week (HBV),Then one month and six months after bih. Administration of HBV vaccine along with HBIG does not diminish the immunologic response to the vaccine.