Mutation that completely disrupts the function of the gene used in which of the following techniques?: (A) Knock out, (B) Non sense mutation, (C) Restriction fragment length polymorphism, (D) Targetted gene disruption
Answer is A. A gene knockout (abbretion: KO) is a genetic technique in which one of an organism&;s genes is made inoperative ("knocked out" of the organism). Also known as knockout organisms or simply knockouts, they are used in learning about a gene that has been sequenced, but which has an unknown or incompletely known function.