Orphan Annie eye nuclei appearance is characteristic of:: (A) Papillary carcinoma thyroid, (B) Carcinoma pituitary, (C) Paraganglioma, (D) Meningioma
Answer is A. - Nuclei of papillary carcinoma cells contain finely dispersed chromatin, which impas an optically clear or empty appearance of nuclei, giving rise to designation ground-glass or Orphan Annie eye nuclei.