Which of the following is NOT an adverse effect of excessive mineralocoicoid action?: (A) Na+ and water retention, (B) Acidosis, (C) Aggravation of CHF associated myocardial fibrosis, (D) Rise in blood pressure
Answer is B. -Mineralocoicoids cause retention of sodium and water. It can result in increase in blood pressure as well as aggravation of symptoms of CHF. -Mineralocoicoids cause loss of K+ and H+ in the urine. This can result in hypokalemia and metabolic alkalosis in mineralocoicoid excess conditions like Cushing syndrome or Conn syndrome.