Which of the following drugs inhibits post translational modification of viral proteins?: (A) Indinavir, (B) Enfuviide, (C) Lamivudine, (D) Zalcitabine
Answer is A. (Ref: KDT 6/e p774) Protease results in the formation of final structural and functional proteins by post translational modification of HIV viral proteins. Drugs in this group are indinavir, saquinavir, lopinavir, ritonavir, amprenavir etc.