The HLA impoant in IDDM is -: (A) HLA-A3, (B) HLA-B27, (C) HLA-DR3/DR4, (D) HLA-W 1
Answer is C. Ans. is 'c' i.e., HLA DR3/DR4 95% of IDDM (Type I Diabetes Mellitus) patients express either HLA DR 3or HLA DR4 or the heterozygous DR/ DR4 configuration. No HLA association is seen with Type II Diabetes mellitus or NIDDM.