The MOST sensitive test to diagnose GERD is:: (A) 24 hour ambulatory pH monitoring, (B) Upper GI endoscopy, (C) Basal acid output measurement, (D) Bernstein test
Answer is A. Gastroesophageal Reflux Disease (GERD) Classic symptoms of gastroesophageal reflux are - water brash and substernal heaburn. Endoscopy is a sensitive test for diagnosis of esophagitis but will miss nonerosive reflux disease (NERD) MUST KNOW: The most sensitive test for diagnosis is 24-h ambulatory pH monitoring. Ref: Harrison, Edition-18, Page-2417.