A primigravida with 38 completed weeks of gestation has gone into labor. Oxytoxin was staed to augment labor. The second messenger system through which oxytoxin acts is ?: (A) cAMP, (B) Phospholipase, (C) cGMP, (D) Tyrosine kinase
Answer is B. The second messenger system through which oxytoxin acts in phospoholipase C mechanism. Hormones acting IP3- DAGor phospholipase C pathway: Acetylcholine (muscuranic) Angiotensin II ] ADH (V1 receptor ) a1 receptor adrenergic hormones Cholecystokinin Gastrin GnRH Oxytoxin TRH GHRH Substance P Ref: internet sources