Apixaban is a new drug that acts by:: (A) Inhibiting TNF alpha, (B) Inhibiting coagulation factor Xa, (C) Inhibiting platelet aggregation, (D) Activating plasminogen
Answer is B. Ans. (B) Inhibiting coagulation factor Xa:(Ref: Harrison 18/e p1000, KDT 8/e p671)Rivaroxaban and Apixaban are newer oral anticoagulants that act by inhibiting factor Xa.Newer oral anticoagulants that are currently being asked in the exams are:Dabigatran (Direct thrombin inhibitor)RivaroxabanApixaban