Most common site for the initiation of otosclerosis is: (A) Food plate of stapes, (B) Margins of stapes, (C) Fissula ante fenestrum, (D) Fissula post fenestrum
Answer is C. In stapedial otosclerosis which is the most common variety, the lesion stas just in front of the oval window in an area called "fissula ante fenestram". Ref: Diseases of EAR, NOSE, THROAT by PL Dhingra; 7th Edition; page no.95