Crohn's disease is associated with polymorphism in:: (A) NOD2/CARD 15 gene, (B) Philadelphia chromosome, (C) P53 gene, (D) APC/Beta catenin
Answer is A. Ans. (a) NOD 2/CARD 15 geneRef: Sabiston 20th edition, Page 1260* IBD-1 (CARD-15/NOD 2 gene) mutation at chromosome 16 q is linked with CD.* IBD-2 - Chr.12q-linked with UC