Which of the following drugs is useful for treatment of advanced prostate cancer?: (A) Ganirelix, (B) Cetrorelix, (C) Abarelix, (D) Goserelin
Answer is D. Drugs used in advanced prostate cancer are : *LHRH agonists ( medical castration ) - leuprolide, goserelin *Phosphorylated diethylstilbestrol *Androgen receptor blocking agents like flutamide, bicalutamide *Cyproterone acetate (also has progestogenic effect ) Ganirelix, cetrorelix and abarelix are GnRH antagonists Reference : page 1050 SRB's manual of surgery 5th edition