Immunosuppressant drug inhibiting the action of IL-2 without inhibiting its transcription is:: (A) Prednisolone, (B) Cyclosporine, (C) Tacrolimus, (D) Sirolimus
Answer is D. Cyclosporine and tacrolimus are calcineurin inhibitors. These inhibit the formation (gene transcription) of interleukins. Sirolimus is mTOR inhibitor. It inhibits the action of interleukins after their formation.