Most common antibody in autoimmune hepatitis is: (A) u1RNP, (B) Anti-5m, (C) ANA, (D) Anti-LKM
Answer is C. Autoimmune hepatitis Indistinguishable from chronic viral hepatitis. Responds to immunosuppressive therapy Female predominance(70%) Absence of serogical evidence of viral infection Presence of other forms of autoimmune diseases like rheumatoid ahritis, thyroiditis, sjogren syndrome and ulcerative colitis. Most patients found to have circulating anti- nuclear antibodies, anti-smooth muscle antibiodies, liver/kidney microsomal antibody, anti-soluble liver/pancreas antigen. ROBBINS BASIC PATHOLOGY NINTH EDITION PAGE 620