Diagnosis of beta Thalassemia is established by: (A) NESTROFT Test, (B) Hb A1c estimation, (C) Hb electrophoresis, (D) Target cells in peripheral smear
Answer is C. Diagnostic test for thalassemia is Hb electrophoresis. NESTROFT Test - Naked Eye Single Tube Red Cell Osmotic Fragility Test - used for screening for Thalassemia HbA1c - Used to assess long term glycemic control in diabetics (blood sugar control over past 3 months) Target cells - A feature of thalassemia, but not diagnostic Reference : Ghai essential of pediatrics, eighth edition, p.no:342