Following are required for normal growth: (A) Proto oncogene, (B) Tumor suppressor genes, (C) Oncogenes, (D) DNA repair genes
Answer is A. A,B,D are answers Ref Robbins 7/e p290; 9/e p280 A proto-oncogene is a normal gene that could become an oncogene due to mutations or increased expression. Proto-oncogenes code for proteins that help to regulate the cell growth and differentiation. Proto-oncogenes are often involved in signal transduction and execution of mitogenic signals, usually through their protein products. Examples of proto-oncogenes include RAS, WNT, MYC, ERK, and TRK.