Superantigens causes -: (A) Polyclonal activation of T-cells, (B) Stimulation of B cells, (C) Enhancement of phagocytosis, (D) Activation of complement
Answer is A. Superantigens are a class of antigens that cause non-specific activation of T-cells resulting in polyclonal T cell activation and massive cytokine release. Superantigens bind first to the MHC Class II and then coordinate to the variable alpha or beta chain of T-cell Receptors . Ref: Ananthanarayan & Panikers textbook of microbiology 9th edition pg:90