All are good prognostic factors for neuroblastoma except: (A) Trk-A expression absent, (B) Absence of 1 p loss, (C) Absence of 17 p gain, (D) Absence of 11 q loss
Answer is A. The expression of specific neurotrophin receptors like TrkA are good prognostic factors for Neuroblastoma whereas expression of TrkB like neurotrophin receptors worsens the disease. Refer robbins 9/e 260p