Torcetrapib induces its hypolipidemic action by-: (A) Inhibiting cholesterol ester triglyceride transport protein, (B) Activating lipoprotein lipase, (C) Inhibiting lipolysis, (D) Inhibiting cholesterol absorption
Answer is A. Ails, is 'a' i.e., Inhibiting cholesterol ester triglyceride transport protein Hypolipidemic drugsHMG-CoA reductase iuhibitors (statins) - Lovastatin, Simvastatin, Pravastatin, Atorvastatin, Rosuvastatin.Bile acid sequestrants (Resins) - cholestyramine, colestipol.Activate lipoprotein lipase (fibric acid derivatives) - clofibrate, gemfibrozil, bezafibrate, fenofibrate.Inhibit lipolysis and triglyceride synthesis - Nicotinic acid.5.Other - Probucol, Gugulipid, Ezetimibe, Avasimibe, Torcetrapib.o Ezetimibe inhibits intestinal cholesterole absorption.o Avasimibe inhibits enzyme acyl Coenzyme A : cholesterol acyl transferase-1 (ACAT-1) which causes esterification of cholesterol.o Torcetrapib inhibits cholesterol ester triglyceride transport protein - | HDL cholesterol.