Sickle Cell anaemia all are true except: (A) The shift from HbF to HbS occurs due to point mutation., (B) Microvascular occlusion is a severe complication of SCA, (C) Deoxygenation of RBC can lead to extensive membrane damage, (D) Adults but not children; with  sickle  cell  disease  are  functionally  asplenic,  making them  susceptible  to  infections  caused  by  encapsulated  bacteria,  such  as  pneumococci.
Answer is D. None