Which of the following can participate in gluconeeogenesis: (A) Acetyl CoA, (B) Propionyl CoA, (C) Muscle glycogen, (D) All of the above
Answer is B. Propionyl CoA
↓
Succinyl CoA
↓
Succinate
↓
Fumarate
↓
Malate
↓
Oxaloacetate ⇒ GLUCONEOGENESIS
Note: Acetyl CoA which is released from even chain fatty acids can't participate in gluconeogenesis Muscles lack glucose-6-phosphatase and hence can't.