Spongiosis involves-: (A) Stratum basal, (B) Stratum corneum, (C) Stratum granulosum, (D) Stratum spinosum
Answer is D. Spongiosis is seen in intracellular ( in between keratinocytes ) edema. This results in loss of cohesion between epidermal cells which remain on contact with each other only at desmosomes and so acquire a stellate appearance giving the epidermis a sponge like appearance. Ref: Harrison20th edition pg 1208