The genetic defect in Dubin-Johnson Syndrome is: (A) Mutation in gene for multiple drug resistance protein 2, (B) Mutation in gene UDP- glucuronyl transferase, (C) Mutation of chromosome 23, (D) Flash mutations
Answer is A. Dubin-Johnson syndrome is a rare, autosomal recessive, benign disorder that causes an isolated increase of conjugated bilirubin in the serum. Classically, the condition causes a black liver due to the deposition of a pigment similar to melanin. Refer robbins 9/e