The combination of alcohol and disulfiram results in nausea and hypotension as a result of accumulation of:: (A) Acetaldehyde, (B) Acetate, (C) Methanol, (D) NADH
Answer is A. Disulfiram is an aldehyde dehydrogenase inhibitor that can be used for de-addiction of chronic alcoholics. Due to inhibition of aldehyde dehydrogenase, there is accumulation of acetaldehyde that leads to several distressing symptoms (which strengthens the resolution of a person to quit alcohol).