All except one are true regarding Barrett's esophagus-: (A) More incidence of sq. cell ca, (B) Metaplasia, (C) Columnar epithelium, (D) Involves lower oesophagus
Answer is A. There is an increased incidence of adenocarcinoma in Barret's esophagus. Barrett's esophagus is a premalignant condition with an increased incidence of adenocarcinoma of esophagus. The risk of adenocarcinoma increases with increasing length of columnar-lined epithelium Also, remember Barrett's esophagus is the single most impoant risk factor for adenocarcinoma of esophagus. The adenocarcinoma develops at the squamo-columnar junction (-85%) or within 2 cm of the junction. Ref : Bailey & Love 25/e p1022