Which of the following hypnotic drugs facilitates the inhibitory actions of GABA but lacks anticonvulsant or muscle relaxing propeies and has minimal effect on sleep architecture?: (A) Buspirone, (B) Diazepam, (C) Phenobarbital, (D) Zaleplon
Answer is D. (Ref: KDT 6/e p398) * Zolpidem, zaleplon and zopiclone are agonists at BZD receptors. * These are hypnotic drugs that lack muscle relaxant and anticonvulsant actions. * These have negligible effect on REM sleep and do not affect sleep architecture.