Which is not transmitted familial:: (A) Factor V Leiden mutation, (B) Thalassemia, (C) Hemophilia, (D) Sickle cell anemia
Answer is A. Ans. a. Factor V Leiden mutationAutosomal recessive diseases*. Often due to defects in structural genes.*. Many generations, both males and females are affected.Sickle cell anemia, ThalassemiasX-linked recessive disorders*. Sons of heterozygous mothers have a 50% chance of being affected.*. No male-to-male transmission.*. Skips generations.Hemophilia