Low doses of aspirin used in myocardial infarction act by -: (A) Inhibiting thromboxane synthetase, (B) Inhibit cyclooxygenase, (C) Releasing EDRF, (D) High protein binding activity
Answer is B. Ans. is 'b' i.e., Inhibit cyclooxygenase Aspirin (in low doses) ---> inhibits synthesis of TXA2 by inhibiting the enzyme cycloxygenase So that immediate precursor (prostaglandins) of TXA2 are not synthesized. o Ticlopidine, clopidogrel -4 they block ADP mediated cAMP inactivation.