Which of the following glucose transpoer mediates insulin stimulated glucose uptake?: (A) SGLT-1, (B) GLUT-1, (C) GLUT-2, (D) GLUT 4
Answer is D. Insulin stimulated glucose uptake into fat and muscle cells is mediated by GLUT 4. Insulin stimulates translocation of a pool of GLUT 4 to the plasma membrane through targeted exocytosis and depress the rate of GLUT4 endocytosis.