Immunoglobulin variation does not depend on -: (A) Light chain, (B) Heavy chain, (C) Amino acid sequence, (D) Constant region
Answer is A. Ans. is 'a' i.e., Light chain The isotype variation or class of antibody is due to variation in the amino acid sequence in the constant region of the heavy chain.Because there are five potential variation in the aminoacid sequence in the constant region there are five classes of antibody i.e. IgG, IgM, IgA, IgD, IgE.