Chromosome associated with familial polyposis colon ? -: (A) Chromosome 5, (B) Chromosome 6, (C) Chromosome 11, (D) Chromosome 13
Answer is A. Robbins and Cotran pathologic basis of disease South Asia edition APC is a member of the class of tumor suppressor that function by downregulating growth promoting signalling pathway . Germline loss of function mutation involving the APC which is present in chromosome 5 are associated with familial adenomatous poliposis..