Which of the following drug can cause Delayed Bone Marrow Suppression leading to Sustained Neutropenia?: (A) Vincristine, (B) Carboplatin, (C) Melphalan, (D) Carmustine
Answer is D. NITROSOUREAS : MOA: Alkylating agent DRUGS: CARMUSTINE, LOMUSTINE, SEMUSTINE. USES: Can cross BBB thereby used in Brain tumors. S/E: Delayed Bone Marrow Suppression resulting in Sustained Neutropenia.