Which of the following is a Dihydropteroate synthase (DHPS) inhibitor?: (A) Pyrimethamine, (B) Trimethoprim, (C) Methotrexate, (D) Dapsone
Answer is D. Dapsone, PAS, Sulphonamide > inhibit DHPS enzyme Pyrimethamine, Methotrexate, Trimethoprim - acts by inhibiting DHFR (Dihydrofolate reductase) enzyme.