Which one of the following statements, concerning persistent hyperplastic primary vitreous (PHPV) is not true?: (A) It is generally unilateral, (B) Visual prognosis is usually good, (C) It may calcify, (D) It is most easily differentiated from retinoblastoma by the presence of exophthalmos or cataract.
Answer is B. B i.e. Visual prognosis is usually good Persistent Hyperplastic Primary Vitreous (PHPV) It is persistence of the primary viterous & hyaloid aerial system. Almost always unilateralQ (-90%) Presents as white pupillary reflex in the new born (congenital leukocoria)Q It is usually associated with - CataractQ - Glaucoma - Long & extended ciliary processes because of pull from contracted retrolental tissue. - MicrophthalmosQ - Intraocular haemorrhage - Tractional RD Investigations: USG & CT Scan D/D with Retinoblastoma on the basis of microphthalmia & elongated ciliary processes If diagnosed early, T/T is aspiration of lens, excision of retrolental membrane and vitrectomy Visual prognosis is poorQ.