Steroid suphatase deficiency is seen in: (A) Ichthyosis vulgaris, (B) Lamellar Ichthyosis, (C) 'X' linked recessive icthyosis, (D) None of the above
Answer is C. X-linked ichthyosis (abbreted XLI) is a skin condition caused by the hereditary deficiency of the steroid sulfatase (STS) enzyme that affects 1 in 2000 to 1 in 6000 males. XLI manifests with dry, scaly skin and is due to deletions or mutations in the STS gene. Ref Harrison20th edition pg 1332