Most specific marker for neural tube defects is: (A) Alpha-fetoprotein, (B) Unconjugated estriol, (C) Acetylcholinesterase, (D) Pseudocholinesterase
Answer is C. Both alpha-fetoprotein and acetylcholinesterase in amniotic fluid are markers for neural tube defects. But acetylcholinesterase is the most specific marker. Ref : Dutta book of obstetrics 8th Ed