The therapeutic efficacy of antihypeensive drugs is blunted by NSAIDs because of :: (A) Cause sodium excretion, (B) Increase in the clearance of antihypeensive drugs, (C) Decrease in the absorption of antihypeensive drugs, (D) Decrease in the synthesis of vascular prostacyclin
Answer is D. NSAIDs inhibit Prostaglandin production including PGI2 which causes vasodilatation Ref: KD Tripathi 8th ed