The following statements regarding finasteride are true EXCEPT:: (A) It is used in the treatment of benign prostatic hyperplasia, (B) Impotence is well documented alter its use, (C) It blocks the conversion of dihydrolestosteron to testosterone, (D) It is a 5 a reductase inhibitor
Answer is C. Finasteride is a competitive inhibitor of enzyme 5 alpha-reductase which conves testosterone into DHT. DHT is a more powerful androgen than testosterone It is used for the treatment of BPH and androgenic alopecia Adverse effect-cause impotence.(Ref.Essentials of medical pharmacology TD Tripathi 7th edition page no.302)