Centrilobular zonal necrosis in liver is seen with which of the following drug?: (A) Carbon tetrachloride, (B) Rifampicin, (C) INH, (D) Yellow phosphorus poisoning
Answer is A. Carbon tetrachloride characteristically produce a centrilobular zonal necrosis, whereas yellow phosphorus poisoning typically results in peripoal injury. Ref: Harrisons Principles of Internal Medicine, 18th Edition, Page 2558.