The estimation of 3 methyl histidine in urine is used to study -: (A) Status of folate in the body, (B) Renal disease, (C) Skeletal muscle, (D) Protein absorption in the gut
Answer is C. 3-Methylhistidine (3-MH) is a post-translationally modified amino acid which is excreted in human urine. Urinary concentrations of 3-methylhistidine serve as a reliable index of skeletal muscle protein breakdown in humans who have been subject to muscle injury. Ref Davidson 23rd edition pg 981