During direct immunofluorescence testing of renal biopsy specimen, lumpy bumby immune deposits are seen with conjugated antibodies against:: (A) IgG, IgM, and IgA, (B) GBM, (C) C3 and C4, (D) IgE
Answer is A. Direct immunofluorescence of renal biopsy specimen Direct immunofluorescence with Conjugated antibodies against IgG, IgM, and IgA to detect the presence of "lumpy-bumpy" immune deposits and Linear IgG or IgA antibodies bound to GBM antibodies against trapped complement proteins (C3 and C4). Ref: Harrison-18, P-2339.