In metabolism of xenobiotics, all of the following reaction occur in phase one except: (A) Oxidation, (B) Reduction, (C) Conjugation, (D) Hydrolysis
Answer is C. Metabolic reactions are classified as phase 1(non-synthetic) and phase 11 (synthetic) reactions . Phase 1 reaction include oxidation, reduction ,hydrolysis cyclization and decyclization etc Phase 11 reaction include glucorinidation, acetylation, motivation, sulfation and glycine conjugation Refer KDT 7/e p22-24