Fluoroquinolones act on -: (A) DNA histone proteins, (B) DNA gyrase, (C) Camp, (D) mRNA polymerise
Answer is B. Ans. is 'b' i.e., DNA gyrase o Fluoroquinolones (including ciprofloxacin) inhibit DNA gyrase and topoisomerase IV. For gram negative bacteria, the primary target is DNA gyrase, while topoisomerase IV is inhibited in gram positive bacteria.