Following are the propeies of Biguanides, EXCEPT:: (A) Decrease hepatic gluconeogenesis, (B) Not contraindicated in renal dysfunction, (C) Can be used along with sulfonylureas, (D) Don't stimulate insulin Release
Answer is B. Biguanides are contraindicated in patients with renal failure, congestive hea failure, alcoholism and hepatic diseases. Ref: Richard Finkel, Michelle Alexia Clark, Pamela C. Champe, Luigi X. Cubeddu (2009), Pharmacology, 4th Edition, Lippincott Williams and Wilkins Publications, United States Page 292