Which of the following statements about terbinafine is false: (A) Its activity is restricted to dermatophytes, (B) It is effective in onchomyosis, (C) It inhibits squalene epoxidase, (D) It is used topically only
Answer is D. (Ref: KDT 6/e p765) Terbinafine is a CIDAL drug against dermatophytes. It can be administered orally or can be applied topically. It acts by inhibiting the enzyme squalene epoxidase resulting in accumulation of toxic squalene.