In which of the following sites do lymphocytes become immunocompetent?: (A) Germinal center of secondary lymphoid nodules, (B) White pulp of the spleen, (C) Thymic coex, (D) Red pulp of the spleen
Answer is C. T lymphocytes mature and become immunocompetent in the coex of the thymus, B lymphocytes mature and become immunocompetent in the bone marrow. After an antigenic challenge, lymphocytes proliferate and differentiate in various lymphoid tissues