All of the following are modes to decrease pain on injection caused by propofol cxcept: (A) Mix lignocaine with propofol, (B) Give fentanyl prior to propofo, (C) Use vein on the dorsum of hand, (D) Cooling of the drug
Answer is C. Propofol is formulated as a lipid emulsion which causes pain during injection that can be decreased by using a large vein, avoiding veins in the dorsum of the hand, prior injection of lidocaine or by mixing lidocaine with propofol prior to injection (2 mL of 1% lidocaine in 18 mL propofol). prior injection of opioid Thicker vein decreases pain on injection caused by propofol.