Which of the anti-microbials is the drug of choice for prophylaxis of meningococcal meningitis?: (A) Ciprofloxacin, (B) Rifampicin, (C) Penicillin, (D) Gentamycin
Answer is B. Rifampin is effective against many gram positive and gram-negative microorganisms. It is the drug of choice for prophylaxis of meningococcal meningitis. Rifampin is used prophylactically in close contacts of patients affected by epiglottitis or meningitis caused by Haemophilus influenza. The drug also used prophylactically against leprosy and in combination with other drugs to treat Legionella.