The Finnish type of congenital nephritic syndrome occurs due to gene mutations affecting the following protein:: (A) Podocin, (B) Alpha-actinin, (C) Nephrin, (D) CD2 activated protein
Answer is C. Congenital nephrotic syndrome of the Finnish type (CNF) is caused by mutations in NPHS1, encoding the slit-diaphragm and podocin-associated protein nephrin. Ref: Robbins Pathologic Basis of Disease, 7th Edition, Pages 983-4; Genetic Diseases of The Kidney By Richard P. Lifton, Stefan Somlo, Gerhard H. Giebisch, 2008, Page 115