Most impoant receptor involved in chemotherapy induced vomiting is:: (A) Histamine H1 receptor, (B) Serotonin 5-HT3 receptor, (C) Dopamine D2 receptor, (D) Opioid m receptor
Answer is B. -5HT3 receptors are present in CTZ and are involved in chemotherapy induced vomiting. -Antagonist of this receptor like ondansetron is drug of choice for chemotherapy induced vomiting.