Trisomy 21 is associated with: September 2008: (A) ALL, (B) AML, (C) Both of the above, (D) None of the above
Answer is C. Ans. C: Both of the aboveChildren with trisomy 21 have a 10-20 fold increased risk of developing acute leukemia.Both AML and ALL can occur.AML, most commonly, is acute megakaryoblastic leukemia.