True about acetazolamide: (A) Increase sodium reabsorption and potassium secretion, (B) Carbonic anhydrase inhibitor, (C) Acts at ascending limb of loop of Henle, (D) Increase aqueous outflow mainly
Answer is B. Ref: Katzung's, 11th ed. pg. 416* Acetazolamide is a carbonic anhydrase inhibitor which acts on the proximal tubule of nephron.* In kidney, it inhibits H+ secretion and HCO3 reabsorption, which inturn reduces sodium reabsorption.* In eye, it reduces the aqueous formation by limiting generation of bicarbonate ion in ciliary epithelium.