Congenital heart disease is most likely in the newborn of mothers suffering from all except:: (A) Systemic lupus erythematosus, (B) Rheumatoid arthritis, (C) Diabetes in pregnancy,, (D) Congenital heart disease of the mother
Answer is B. Lets analyse each option separately
“Fetal congenital cardiac disease is increased by 3–10% if either of the parents have congenital heart lessons.”
Dutta 7/e, p 276. (so option d is correct)
“Neonatal lupus syndrome is due to crossing of maternal lupus antibodies (anti-Ro or anti-La) to the fetus causing hemolytic anemia, leukopenia and thrombocytopenia. Isolated congenital heart block is present in about one-third of cases. An apparently healthy woman delivering a baby with congenital heart block should be observed for the development of SLE.”
Dutta 7/e, p 293 (i.e. option a is correct)
Matenal diabetes we all know leads to fetal heart disease (Dutta 7/e, p 284), so our answer by exclusion is rheumatoid arthritis.