In which of the following palpable purpura is not seen?: (A) HSP, (B) Scurvy, (C) Mixed cryoglobulinema, (D) ITP
Answer is D. ITP causes non palpable purpura. Palpable purpura is the hallmark lesion of leukocytoclastic vasculitis (small vessel vasculitis) Causes of palpable purpura: Vasculitis Cutaneous small vessel vasculitis PAN Emboli Acute meningococcemia Disseminated gonococcal infection Rocky mountain spotted fever Ecthyma gangrenosum Causes of non-palpable purpura: Clotting disturbances Vascular fragility Thrombi Emboli Possible immune complex