Marchiafava-Bignami diseaseis characterized by?: (A) Callosal atrophy, (B) Cerebellar atrophy, (C) Brainstem atrophy, (D) Cerebral peduncular atrophy
Answer is A. Ans AIt is a rare CNS disorder associated with chronic alcoholism or malnutrition. On imaging there is corpus callosal atrophy and demyelination.Sandwich sign and ears of lynx sign maybe seen.