A patient has a frequent tendency of migraine attacks. Which of the following drug should be given as prophylaxis?: (A) Propranolol, (B) Pindolol, (C) Ergotamine, (D) All of the above
Answer is A. Prophylaxis of migraine is required if the attacks are frequent (>2-3 per month). The drugs useful for prophylaxis are: 

Propranolol is the most commonly used drug for prophylaxis of migraine attacks.
Timolol, atenolol, metoprolol and nadolol can also be used but the drugs with ISA (e.g. pindolol) are ineffective.