All of the following are true about medulloblastoma except:: (A) Occur predominantly in children, (B) Most common site is Vermis, (C) Carmustine and vincristine are used for recurrences and in children <3 years to avoid radiation therapy, (D) Radiotherapy is the main treatment modality
Answer is D. Medulloblastoma Most common malignant brain tumor of childhood- M/C site - Cerebellum (vermis) In adults most common site is Lateral Cerebellar hemisphere Most radiosensitive brain tumor Has CSF spread - given Craniospinal irradiation. Treatment - Despite of extreme radiosensitivity, it should be surgically excised. - Surgical excision should be followed by radiotherapy andchemotherapy. - Carmustine (BCNU) and vincristine are primarily used for recurrences, in poor- risk patients, and in children <3 years to avoid radiation therapy.