Which immunoglobulin combination is predominantly in pathogenesis of cryglobulinemic vasculitis: (A) IgA + IgG, (B) IgM + IgG, (C) IgA + IgE, (D) IgE + IgM
Answer is B. Answer- B. IgM + IgGcryoglobulinemic vasculitis occurs when an aberrant immune response to hepatitis C infection leads to the formation of immune complexes consisting of hepatitis C antigens,polyclonal hepatitis C-specific IgG, and monoclonal IgM rheumatoid factor.