Massive splenomegaly is least likely to occur in: (A) CML, (B) Primary thrombocytosis, (C) PCV, (D) Primary myelofibrosis
Answer is B. Thrombocytosis is defined as a platelet count greater than 400 x 109/L. ... The presence of chronic thrombocytosis, thrombohemorrhagic complications, microvascular symptoms, or splenomegaly ors the diagnosis of primary thrombocytosis. Spleenomegaly is least likely to occur. Ref ganong's review of medical physiology 25e