Trinucleotide repeat seen in Fragile X syndrome is: (A) CGG, (B) CTG, (C) CAG, (D) GAA
Answer is A. Examples of Trinucleotide-Repeat DisordersDiseaseRepeatFragile X syndromeCGGFriedreich ataxiaGAAMyotonic dystrophyCTGSpinobulbar muscular atrophy(Kennedy disease)Huntington diseaseSpinocerebellar ataxiaCAGRef: Robbins and Cotran Pathologic Basis of Disease; 9th edition; Chapter 5; Genetic Disorders; Page no: 168