Which of the following is true of cholera-(: (A) Recent epidemic was due to classical type, (B) Causes secretory diarrhoea, (C) Caused by endotoxin, (D) Vibriocidal antibodies correspond to susceptibility
Answer is B. Ans. is 'b' i.e., Causes secretory diarrhoea . Recent epidemic was due to non-01 V.cholerae (NAG vibrio) in 1992. This strain was designated serovar 0-139 (0-139 Bengal). . Enterotoxin (Cholera toxin) causes watery diarrhea by acting directly on secretory mechanism through cAMP. . Cholera is due to exotoxin (cholera toxin). Cholera vibrios also possess lipopolysaccharide (endotoxin), but it has no role in pathogenesis. . "Vibriocidal antibodies in serum have been associated with protection against colonization and disease"