HIV infects most commonly:: (A) CD4+helper cells, (B) CD8+cells, (C) Macrophage, (D) Neutrophil
Answer is A. Ans. is 'a' i.e., CD4 Helper cells The receptor for the virus is the CD4 antigen on surface. The cells affected are:- CD4 T Cells (major target).- B lymphocytes.- Monocytes and macrophages.- Langerhans cells in dermis.- Glial cells and microglia in the CNS.- Follicular dendritic cells from tonsils can be infected by HIV without the involvement of CD4.