Regarding alpha fetoprotein true statement is:: (A) Major source in fetal life is yolk sac, (B) Commonly increased in wilm's tumour, (C) Maximum level at 20th week, (D) Half-life 5-7 days
Answer is A. AFP Produced by yolk sac and fetal liver Highest level of AFP in feta lserum and amniotic fluid isreached around 13 weeks and thereafter it decreases. Maternal serum level reaches peak around 32 weeks and increased in hepatoma,NTD,Rh isoimmunisation,IUFD,Multiple pregnancy D.C.DUTTA'S TEXTBOOK OF OBSTETRICS,Pg no:106,7th edition