Which among the following is indicative of bone resorption?: (A) Osteocalcin, (B) Urine hydroxyproline, (C) Bone specific alkaline phosphatase, (D) Type 1 procollagen
Answer is B. Markers of bone formation: Markers of bone resorption: Serum bone specific alkaline phosphatase --Serum osteocalcin Serum carboxy terminal extension peptide of pro-collagen-1 Serum type I collagen extension peptide Urine and serum cross-linked N telopeptides Urine and serum cross-linked C telopeptides Urine hydroxyproline Urine deoxypyridinoline Urine hydroxylysine glycosides Serum TRAP (Taarate resistant acid phosphatase) --Serum bone sialoprotein