You are in the eye OPD and wish to use a topical beta blocker in a patient. The chosen drug by you should have all the following propeies EXCEPT:: (A) Strong local anaesthetic activity, (B) High lipophilicity, (C) High ocular capture, (D) Low systemic activity
Answer is A. Drugs possessing local anaesthetic propey increases the risk of corneal ulcers. Timolol and betaxolol are the preferred b-blockers for the treatment of glaucoma because they lack local anaesthetic activity.