If both parents have sickle cell anemia, then the likelihood of children (offsprings) having the disease is-: (A) 10%, (B) 25%, (C) 50%, (D) 100%
Answer is D. Sickle cell anemia Inherited as AR. If both parents are affected, means both parents are homozygous for trait as recessive allele is expressed in only homozygous state. Then 100 % offsprings will inherit the disease. If Both parents are carriers then only 25% will be affected