Which of the following is most likely due to a pharmacogenetic condition?: (A) Hypoglycemia by insulin, (B) Tachycardia by albuterol, (C) Metoclopramide induced muscle dystonia, (D) Primaquine induced hemolytic anemia
Answer is D. * Primaquine is an oxidant drug. It can cause hemolytic anemia in subjects having deficiency of G6PD enzyme. * This condition is genetically determined. * Other three options i.e hypoglycemia due to insulin, tachycardia by Albuterol and metoclopramide induced dystonia are dose dependent adverse effects.