All of the following statements about Lipoprotein Lipase are true, except:: (A) Found in adipose tissue, (B) Found in myocytes, (C) Deficiency leads to hyperiacylglycerolemia, (D) Does not require CII as cofactor
Answer is D. Apo CII is needed for the activation of lipoprotein lipase. Lipoprotein lipase activated by apo CII on circulating lipoprotein paicles, hydrolyzes the triacylglycerol contained in these paicles to yield fatty acid and glycerol. Ref: Biochemistry By Richard A. Harvey, Denise R. Ferrier, Pages 228-9