Drug of choice for the treatment of Taenia solium and Taenia saginata infestation is-: (A) Metronidazole, (B) Albendazole, (C) Niclosamide, (D) Diloxanide foroate
Answer is C. Niclosamide is highly effective against Taenia solium & T.saginata. It acts by inhibiting oxidative phosphorylation in mitochondria & interfering with anaerobic generation of ATP by the tapeworm . Injured by niclosamide, the tapeworm are paly digested in the intestine. Reference: Harrison20th edition pg 1137