On repeated use, which of the following inhalational anaesthetic agent can cause hepatitis:: (A) Isoflurane, (B) Halothane, (C) Sevoflurane, (D) Ether
Answer is B. Halothane causes auto immune hepatitis Halothane produces byproduct during metabolism which causes autoimmune hepatitis Auto immune hepatitis d/t repeated use of halothane, preexisting liver dysfunction More seen in female patients, obese patients & middle age patients