Among the given conditions the least infectious type of TB is seen in which of the following associations?: (A) Cavitary pulmonary disease, (B) Laryngeal TB, (C) Sputum with 1,00,000 AFB/ml, (D) HIV patients with TB
Answer is D. The most infectious patients have cavitary pulmonary disease or, much less commonly, laryngeal TB and produce sputum containing as many as 105-107 AFB/mL. Persons with both HIV infection and TB are less likely to have cavitations, they may be less infectious than persons without HIV co-infection. Reference: Harrisons Principles of Internal Medicine, 18th Edition, Page 1342