All of the following statements about methotrexate are true EXCEPT:: (A) It is cell cycle specific and kills cells in the S phase, (B) Its toxicity primarily affects bone marrow and epithelial structures, (C) Folic acid reverses its toxic effects, (D) It is the drug of choice for choriocarcinoma
Answer is C. Folinic acid (leucovorin) is used to reverse the adverse effect of methotrexate. Folic acid is ineffective. All other statements are true