Fanconi's anemia is a:: (A) Constitutional anemia, (B) Hemolytic anemia, (C) Iron deficiency anemia, (D) Auto-immune anemia
Answer is A. a. Constitutional anemia(Ref: Nelson's 20/e p 2390-2392, Ghai 8/e p 349-351)Constitutional pancytopenia is defined as decreased marrow production of the 3 major hematopoietic lineages on an inherited basis, resulting in anemia, neutropenia and thrombocytopenia. Important causes are:Fanconi anemiaAmegakaryocytic thrombocytopeniaShwachman-Diamond syndromeDown syndromeDyskeratosis congenitaNoonan syndrome