The best investigation for the diagnosis of amyloidosis is: (A) Colonoscopy, (B) Rectal biopsy, (C) Upper GI endoscopy, (D) CT scan
Answer is B. Diagnosis Microscopic examination - biopsies from kidney, gingiva, rectum Congo red staining on abdominal fat aspirates Serum & urine protein electrophoresis Bone marrow aspiration - to r/o plasmacytosis Scintigraphy with radiolabelled serum amyloid P (SAP) component