Which of the following is the characteristic histological feature of HIV associated collapsing glomerulopathy?: (A) Crescent formation, (B) Mesangial deposition, (C) Subepithelial deposition with endothelial cell proliferation, (D) Hyperophy and proliferation of visceral epithelial cells
Answer is D. HIV associated Nephropathy- leads to development of FSGS ( focal segmental glomerulosclerosis ) Most commonly associated with HIV is collapsing glomerulopathy. These patients have rapid kidney deterioration . Histologically, it is associated with hyperophy & proliferation of visceral epithelial cells.