Alpha 1 anti -trypsin in stool is indicative of:: (A) Protein losing enteropathy, (B) Chronic pancreatitis, (C) Acute pancreatitis, (D) Whipple disease
Answer is A. Alpha-1-antitrypsin (a-1-AT)- glycoprotein, which is produced by the liver, intestinal macrophages, monocytes and mucous membrane cells of the gut. Belongs acute phase proteins Lack of a-l-AT-enhanced proteolysis. . Measurement of a-1-AT in stool reflects the permeability of the gut during inflammatory processes.