Which of the following is a ribozyme?: (A) Peptidyl transferase, (B) Elongation factor 2, (C) Primase, (D) RNA polymerase
Answer is A. Interestingly, some RNA molecules have intrinsic catalytic activity. The activity of these RNA enzymes, or ribozymes, often involves the cleavage of a nucleic acid. Two ribozymes are the peptidyl transferase that catalyzes peptide bond formation on the ribosome, and ribozymes involved in the RNA splicing.Ref: Harpers Illustrated Biochemistry, 30th edition, page no: 363