Which of the following is the necessary pre-operative investigation which has to be done in a patient with Down's syndrome posted for surgery?: (A) CT Brain, (B) Echocardiography, (C) Ultrasound Abdomen, (D) X-Ray cervical spine
Answer is B. Down's syndrome is associated with cardiac manifestations such as Endocardial cushion defect, ASD, VSD and Tetrology of fallot. So echocardiography is the necessary pre-operative investigation to be done before surgery in a patient with Downs' syndrome. Ref: Harrison's Principles of Internal Medicine, 16th Edition, Page 1382