What is the best prognostic indicator of multiple myeloma at the time of diagnosis ?: (A) Number of myeloma cells in the marrow, (B) Beta 2 microglobulin, (C) Alkaline phosphatase level, (D) Hypercalcemia
Answer is B. Ans. is 'b' i.e., Beta-2 Microglobulins o Serum /32 microglobulin is the single most powerful predictor of survival and can substitute for staging.P2 Microglobulin level :< .004g/L Median survival of 43 months.> .004 g/L Median survival of only 12 months.