Endotoxin from gram negative organism is :: (A) Polysaccharide, (B) Glycoprotein, (C) Lipoprotein, (D) Lipo-polysaccharide
Answer is D. Ans. is 'd' i.e. Lipopolysaccharide Distinguishing feature of Exotoxin and endotoxiinsExotoxinsEndotoxins* Proteins** Lipopolysaccharide** Heat labile** Heat stable** Secreted by cells** forms part of cell wall** Action enzymic** No enzymic action** Active in minute dose ** Active only in large dose** Highly antigenic** Weakly antigenic** Action specifically neutralised by antibody* Neutralisation of antibody ineffective* Specific pharmacologic effect for each toxin ** Effect nonspecific** Can be toxoided* Cannot be toxoided