The earliest morphological evidence of ovulation on endometrial biopsy is :: (A) Pseudostratification, (B) Basal vacuolation, (C) Decrease in glycogen content, (D) Predecidual reaction
Answer is B. Endometrial biopsy Consists of curretting small pieces of endometrium from the uterus with small endometrial biopsy curette, preferably 1-2 days prior to menstruation Material removed is fixed immediately in formalin saline Secretory changes (basal vacuolation) proves that cycle has been ovulatory Ref: Shaw's Textbook of Gynaecology, 15th edition, page no: 215