Nelson syndrome is seen in:: (A) Adrenalectomy, (B) Hypopitutarism, (C) Deficiency of beta cells, (D) Deficiency of growth hormone
Answer is A. a. Adrenalectomy(Ref: Nelson's 20/e p 2714-2723, Ghai 8/e p 526-527)Adrenalectomy, in a case of pituitary adenoma, may lead to increased ACTH secretion by an unresected pituitary adenoma, evidenced mainly by marked hyperpigmentation; this condition is termed Nelson syndrome.