A 5 year old girl came with history of progressively increasing pallor since bih and hepatosplenomegaly. Which of the following is the most relevant test for achieving diagnosis -: (A) Hb electrophoresis, (B) Peripheral smear examination, (C) Osmotic fragility test, (D) Bone marrow examination
Answer is A. <p>Hb electrophoresis helps to confirm beta thalassemia (Hb F increased ,HbA2 increased ). </p><p>Reference :Harsh mohab textbook of pathology sixth edition pg no 322.</p>