A five year old boy presents with precocious puberty and a blood pressure of 130/80 mmHg. Estimation of which of the following will help in diagnosis -: (A) | 17 hydroxy-progesterone, (B) | Cortisol, (C) | Aldosterone, (D) Renin
Answer is A. Ans- A. Ref- Nelson Textbook Of Pediatrics Vol. 1 20th ed Biochemical diagnostic studies show elevated levels of serum 17-OHP, the substrate for the defective 21-hydroxylase enzyme activity.