In liver, which of the following is responsible for metabolism of alcohol?: (A) Alcohol dehydrogenase (ADH), (B) Aldehyde dehydrogenase (ALDH), (C) Microsomal ethanol-oxidizing system(MEOS), (D) All of the above
Answer is D. Alcohol is conveed to acetaldehyde by alcohol dehydrogenase . Acetaldehyde is conveed to acetate by aldehyde dehydrogenase . acetate is conveed to carbon dioxide & water . In addition to alcohol dehydrogenase small amount of alcohol are oxidized by hepatic microsomal enzymes as well . Ref KD Tripathi 8th ed.