True about Rheumatic hea disease and Rheumatic fever is/are -: (A) Caused by group 'A' streptococci, (B) Caused by group 'B' streptococci, (C) Carrier have high risk of developing RF, (D) Carrier have low risk of developing RF
Answer is A. Ref: R Alagappan - Manual of Practical Medicine 4th Edition.pg no: 146 Rheumatic Fever Acute, recurrent, inflammatory disease, mainly of children (aged 5-15 years), typically occurring 1-5 weeks after group A streptococcal infection. Pathophysiology 1. Cross reactivity of host antistreptococcal antibodies to cardiac antigens 2. Microbe initiated autoimmune reactivity.