30 year old Suresh has found to have bilateral lymphadenitis with non caseating granulomas. Your diagnosis is?: (A) TB, (B) Lymphoma, (C) Sarcoidosis, (D) Any of the above
Answer is C. Sarcoidosis is a multisystem inflammatory disease of unknown etiology that predominantly affects the lungs and intrathoracic lymph nodes. Sarcoidosis is manifested by the presence of noncaseating granulomas (NCGs) in affected organ tissues. T cells play a central role in the development of sarcoidosis.