All of the following immunosuppressives cause profound myelosuppression except-: (A) Sirolimus, (B) Cyclosporine, (C) Azathioprine, (D) Mercaptopurine
Answer is B. Pharmacokinetics, mechanism of action, clinical efficacy in organ transplants, adverse effects, and dosage and administration of cyclosporine, a new immunosuppressant, are reviewed .Cyclosporine acts by blocking T-lymphocyte function without causing myelosuppression Ref Harrison 20th edition pg 578