Which of the following is NOT a prodrug :: (A) Lisinopril, (B) Enalapril, (C) Levodopa, (D) Sulindac
Answer is A. Ans. is 'a' Lisinopril Examples of prodrugProdrugActive form* Levodopa*-Dopamine* Enalapril*-Enalaprilat* Sulindac*-Sulfide metabolite* Becampicillin*-Ampicillin* Sulfasalazine*-5-Aminosalicylic acid* Prednisone*-Prednisolone* Zidovudine-Zidovudine triphosphate* Cyclophosphamide*-AldophosphamideProdrugs offer following advantage over the active form :In being more stableHaving better bioavailabilityLess side effects and toxicity