Metabolic abnormality seen in large colorectal villous adenoma: (A) Hypokalemic metabolic acidosis, (B) Hypokalemic metabolic acidosis, (C) Chlorine sensitive metabolic acidosis, (D) Chlorine resistant metabolic alkalosis
Answer is B. .Features of Adenoma * Can be asymptomatic. * Bleeding per anum is usually chronic but rarely can be acute. * Anaemia. * Prolapse--common in tubular type. * Diarrhoea common in villous type; mucus discharge. * Tenesmus, colicky abdominal pain. * Spurious diarrhoea. * Poor general health. * Electrolyte imbalance - hypokalaemia. * Per-rectal examination should be done to feel the adenoma/polyp. * Carcinomatous changes. ref:SRB&;s manual of surgery,ed 3,pg no 832