Intracellular accumulation of which of the following forms Russell bodies ?: (A) Immunoglobulins, (B) Cholesterol, (C) Phospholipids, (D) Lipoproteins
Answer is A. Intracellular accumulation of immunoglobulins that can occur in plasma cells or RER forms large rounded , eosinophilic Russell bodies. Multiple aggregates of Russell bodies forms Mott cells. Dutcher bodies- single and usually large pale staining nuclear inclusions that are common in IgA myeloma.