Prefilaggrin is found in which layer of epidermis?: (A) Stratum corneum, (B) Stratum granulosum, (C) Stratum spinosum, (D) Stratum basale
Answer is B. Prefilaggrin(precursor molecule) is found in the keratohyaline granules present in the stratum granulosum. Filaggrin is most abundantly present in Stratum corneum. Filaggrin - helps in filament aggregation