Most impoant receptors involved with schizophrenia are?: (A) GABAA, (B) GABA,,, (C) DZd, (D) 5-HT
Answer is C. Ans. C. DZdDopamine hypothesis is the most accepted hypothesis for schizophrenia. There is hyperactivity of dopaminergic system. This hypothesis is suppoed by :Amphetamine and cocaine which release dopamine in central synapses induce schizophrenia like symptoms; andAntipsychotic drugs control the schizophrenic symptoms by blocking dopamine (D2) receptors.