Xeroderma pigmentosum is caused due to:: (A) DNA synthesis defect, (B) Ectodermal cell migration defect, (C) Abnormal nucleotide excision repair, (D) Melanocyte proliferation
Answer is C. Xeroderma pigmentosum (XP) is a rare autosomal recessive disease characterized by photosensitivity, pigmentary changes, premature skin ageing, neoplasia and abnormal Nucleotide excision repair. Ref: Rook's textbook of dermatology, 8th edition, Pg15.71.