Ciprofloxacin should not be used with theophylline because-: (A) it decreases efficiency of theophylline, (B) it increases toxicity of theophylline, (C) it decreases efficiency of ciprofloxacin, (D) it decreases absorption of theophylline
Answer is B. Ans. is 'b' i.e., It increases the toxicity of theophylline Impoant interactions of FOs o Plasma concentration of theophylline, caffine and warfarin are increased by ciprofloxacin, norfloxacin and pefloxacin. o NSAIDSs enhance CNS toxicity of FQS. o Antacids, sucralfate and iron salts reduce absorption of FQs.