In a patient with wilson disease related compensated cirrhosis, without evidence of neurologic or psychiatric symptoms the best treatment option is:: (A) Trientine, (B) Zinc, (C) Tetrathiomolybdate, (D) d-penicillamine
Answer is B. For patients with hepatitis or cirrhosis, but without evidence of hepatic decompensation or neurologic/psychiatric symptoms, zinc is the treatment of choice. Zinc has proven efficacy in Wilson's disease and is nontoxic. Reference: Harrisons Principles of Internal Medicine, 18th Edition, Page 3189