Which of the following sites is responsible for the amnestic defect in Wernicke&;s Korsakoff syndrome:: (A) Mamillary body, (B) Thalamus, (C) Periventricular Grey matter, (D) Hippocampus
Answer is B. The Amnestic effect in Wernicke&;s Korsakoff Syndrome is related to lesions in the dorso-medial nuclei of the thalamus. REF: Harrison book of internal medicine 21ST EDITION