Which antithyroid medication is used in pregnancy?: (A) Methimazole, (B) Carbimazole, (C) Propylthiouracil, (D) All of the above
Answer is C. Ans. is 'c' i.e., Propylthiouracil o Both carbimazole and propylthiourcil can be used during pregnancy, but propyl-thiouracil is the drug of choice because its greater protein binding allows low doses of propylthioracil to be transferred across the placenta and therefore less chance of hypothyroidism.