In thromboasthenia there is a defect in –: (A) Platelet aggregation, (B) Platelet adhesion, (C) Decreased ADP release, (D) Desordered platelet secretion
Answer is A. Platelet adhesion

Platelet adhesion referes to the binding of platelets to subendothelial matrix.
Platelet membrane glycoprotein Ib-IX is essential for platelet adhesion to subendothelial matrix.


Platelet aggregation

Platelet aggregation referres to adherence of platelets to one another.
Platelet membrane glycoprotein ddb-IIIa helps in aggregation.

Congenital dysfunction of platelet
1. Bernard-soulier syndrome

Defect in platelet adhesion due to inherited deficiency of glycoprotein Ib-IX.

2. Glanzmann's thrombasthenia

Defect in platelet aggregation due to inherited deficiency of glycoprotein Ilb-IIIa.