Glanzmann thrombasthenia is due to: (A) Decreased GpIb, (B) Decreased GpIIb/IIa, (C) Anti-GpIIb/IIIa antibodies, (D) Inhibition or deficiency of ADAMTS 13
Answer is B. Glanzmann thrombasthenia is an autosomal recessive disorder. There is a failure of primary platelet aggregation with ADP or collagen due to inherited deficiency of two platelets membrane glycoproteins. It is caused due to deficiency of glycoprotein IIb- IIa.