Leiden mutation is associated with?: (A) Factor IV, (B) Factor V, (C) Factor VIII, (D) Factor IX
Answer is B. Leiden mutation is associated with factor 5.This is also a autosomal dominant disorder in which mutation lies in the replacement of arginine by glycine at position 506.Most common cause of thrombophilia. Reference :Harsh Mohan textbook of pathology 7th edition.Pg no.102