Down Syndrome, All are seen except: (A) t (14 ; 21), (B) Trisomy 21, (C) t (11:14), (D) t (15:21)
Answer is C. Majority of translocations in Down syndrome are fusions at the centromere between chromosomes 13,14,15,21 and 22.These are known as Robeson I an translocation. t(11:14 ) is not seen in down syndrome. Reference : Nelson TB of pediatrics 19th edition pg 402.