Which of the following drugs is most likely to cause loss of equilibrium and auditory damage?: (A) Amikacin, (B) Ethambutol, (C) Isoniazid, (D) Rifabutin
Answer is C. (Ref: KDT 6/e p731, 732) Clindamycin is excreted by biliary route and therefore can be used safely in renal dysfunction. Other drugs excreted in bile are: - Ampicillin - Nafcillin - Chloramphenicol - Novobiocin - Rifampicin - Doxycycline