A shift to the right in the biological activity dose- response curve for a hormone with no accompanying change in the maximal response indicates:: (A) Decreased responsiveness and decreased sensitivity, (B) Increased responsiveness, (C) Decreased sensitivity, (D) Increased sensitivity and decreased responsiveness
Answer is C. Ans. C. Decreased sensitivityRight or left shifts in dose-response curves indicate changes in sensitivity. Changes in maximal biological response indicate changes in responsiveness. Because there is no change in maximal response, the correct answer must relate to a change in sensitivity only. A right shift indicates decreased sensitivity.