Which of the following cytokine have endogenous pyrogenic activity?: (A) IL-8, (B) IL-6, (C) TGF-b, (D) IL-3
Answer is B. Cytokine functions IL-3 Multi-CSF(induce growth of all type of hematopoietic cells in soft agar) IL-6 Endogenous pyrogenic activity Promote B-cell differentiation IgG production IL-8 Neutrophil chemotactic factor TNF-beta Induce other cytokines IL-1 and TNF -alpha are also responsible for pyrogenic avtivity.