Prostaglandin causing fever is:: (A) PGF2, (B) PGE2, (C) PGE1, (D) PGT2
Answer is B. Pyrogenes Substances that cause fever. May be exogenous (Bacterial toxins) and endogenous (IL-1, TNF a, IL-6, Interferons). In the hypothalamus, the prostaglandins, especially PGE2, stimulate the production of neurotransmitters that reset the temperature set point at a higher level.