Best provocative test for diagnosis of Gastrinoma is:: (A) Ca++ infusion test, (B) Secretin injection test, (C) ACTH stimulation test, (D) Steroid assay
Answer is B. Answer is B (Secretin injection test) Gastrinomas (Zollinger Ellison Syndrome) are characterized by peptic ulceration due to hypersecretion of gastrin by a non-beta cell tumor. Secretin injection test is the most valuable provocative test in identifying patients with ZES.