Which one of the following is best associated with Lumefantrine ?: (A) Antimycobacterial, (B) Antifungal, (C) Antimalarial, (D) Antiamoebic
Answer is C. Lumefantrine is a fluorene arylaminoalcohol derivative, it has marked blood schizonticidal activity against a wide range of plasmodia. So it is used as an antimalarial drug. It exes its antimalarial effect by interacting with heme, a degradation product of hemoglobin metabolism. Ref: Malaria Control in Complex Emergencies: An Inter-agency Field Handbook By World Health Organization, Page 77; Harrison's Principles of Internal Medicine, 18th Edition, Chapter 26