Which of the following is an Integrase inhibitor used to treat HIV?: (A) Maraviroc, (B) Ritonavir, (C) Raltegravir, (D) Enfluviritide
Answer is C. Integrase InhibitorsHIV integrase aids the inseion of viral DNA into host cell DNA. This occurs after the viral reverse transcriptase (RNA/DNA-dependent DNA polymerase) produces double-stranded viral DNA. This step is key to the cell becoming a permanent carrier. Two integrase inhibitors, raltegravir and elvitegravir, are approved for use.Ref: Sherris microbiology; 6th edition; Page no: 158