Which of the following are/is not an activator of alternate complement system?: (A) Factor H, (B) IgA, (C) Bacteria, (D) Toxin
Answer is A. Ans. (a) Factor H(Ref: Robbins 9th/pg 162-164)The alternative pathway, can be triggered by microbial surface molecules (e.g., endotoxin, or LPS), complex polysaccharides, cobra venom, and other substances, in the absence of antibodyFactor I and H inhits complement activation