Which is the earliest histopathological change in myocardial infarction?: (A) Stretching and waviness of fibers, (B) Neutrophilic infiltration, (C) Coagulative necrosis, (D) Fibrovascular response
Answer is A. Time frameLight microscopy0-6 hoursNo change, stretching and waviness of fibres6-12 hoursCoagulative necrosis begins with neutrophilic infiltration48-72 hoursCoagulative necrosis is complete3rd-7th dayInitiation of resorption of necrosed fibres and fibrovascular response3rd weekNecrosed muscles removed and in growth of fibrocollagenous tissue.