Following an appendectomy, a 28-year-old man is placed on ceftizoxime sodium (Cefizox). This antibiotic is unlikely to be effective against which of the following?: (A) Pseudomonas, (B) Staphylococcus aureus, (C) Neisseria gonorrhoeae, (D) Bacteroides fragilis
Answer is A. Cefizox is not effective against many strains of Pseudomonas. If the drug is used in pseudomonas infection a higher dosage may be indicated, and the antibiotic should be changed if a quick response does not occur. Complications include cross reactions in patients who are allergic to penicillin. It does not seem to have nephrotoxic side effects.