Which of these is a conservative mutator: (A) Glutamic acid-glutamine, (B) Histidine-glycine, (C) Alanine-leucine, (D) Arginine-aspartic acid
Answer is C. Conserved mutation means altered AA has same properties of original AA. e.g. glutamic acid to aspartic acid (both acidic) or alanine to leucine (both aliphatic).