Streptococcal Toxic shock syndrome is due to the following virulence factor :: (A) M protein, (B) Pyrogenic exotoxin, (C) Streptolysin O., (D) Carbohydrate cell wall.
Answer is B. Ans. is 'b' i.e. Pyrogenic exotoxin Streptococcal toxic shock syndrome is caused due to the release of pyrogenic exotoxins or erythrogenic exotoxins. * These exotoxins are produced only by few strains of beta hemolytic group A streptococci. *Usually these toxins cause scarlet fever but sometimes these strains produce exotoxins that are superantigens.These superantigens (exotoxins) directly super stimulate T cells to pour out inflammatory cytokines. This causes streptococcal toxic shock syndromeMore questions on erythrogenic or pyrogenic exotoxinsDick testIt is a test used to identify children susceptible to scarlet fever.Intradermal injection of erythrogenic toxin into susceptible individual produces an erythematous reaction.Schultz Charlton reactionIt is a diagnostic test for scarlet fever.Blanching of the rash produced during scarlet fever on local injection of convalescent serum is called Schultz Charlton reaction.Also know: