Mechanism of action of aminoglycosides is -: (A) Inhibition of protein synthesis, (B) Image to cell membrane, (C) Coagulation of proteins, (D) Inhibition of cell wall synthesis
Answer is A. Ans. is 'a' i.e., Inhibition of protein synthesis BactericidalBacteriostaticProtein synthesis inhibitorsAminoglycosides, StreptograminsTetracycline, chloramphenicol Macrolides, Lincosamides Linazolide Continued...Cell wall synthesis inhibitorsPenicillin, cephalosporins, Vancomycin, Bacitracin, Cycloserine, Fosfomycin Drugs acting on cell membranePolypeptide - Polymixin B, colistin, tyrothricin AntitubercularINH, Rifampicin, Pyrazinamide streptomycinEthambutolDrugs affecting intermediary metabolismCombination of two drugs may be bactericidal, e.g. cotrimoxazoleSulfonamide, Trimethoprim, ethambutolDrugs affecting DNAQuinolones, metronidazoleNitrofurantoin, Novobiocin