All of the following are minor criteria for multiple myeloma except -: (A) Plasmacytosis 20%, (B) Multiple lytic lesion, (C) IgA < 100 mg/dl and IgG < 600 mg/dl, (D) Plasmacytoma on tissue biopsy
Answer is D. Final Diagnosis -- Nonsecretory multiple myeloma. Diagnostic requirements: The diagnosis of multiple myeloma requires a minimum of one major criterion and one minor criterion, or three minor criteria which must include bone marrow plasmacytosis of 10-30 percent and the presence of a monoclonal protein. Ref Davidson 23rd edition pg 789