Peibaldism refers to: (A) Androgenic alopecia, (B) Erythema nodusum leprosum, (C) Associated with white forelock, (D) None of the above
Answer is C. Piebaldism is an uncommon congenital autosomal dominant, stable patterned leukoderma characterized by a frontal, median or paramedian depigmented patch with a white forelock. There are also macules with scattered hyperpigmented islets. Mutations in the KIT gene on chromosome 14 are the cause. A white forelock on a white triangular elongated or diamond- shaped macule on the forehead from bih is the classical feature in 80%-90%of cases. It is due to defect in migration of melanoblasts from neural crest to skin and hair follicles. melanocytes and melanin are absent at the site of lesions IADVL textbook of dermatology , pigmentary disorders , page 743