Roopa Devi, a 65-year-old female with ovarian cancer is being treated with cisplatin-based chemotherapy. All of the following are used to limit the toxicity of cisplatin except:: (A) N-acetylcysteine, (B) Slow rate of infusion, (C) Chloride diuresis, (D) Amifostine
Answer is A. N-acetylcysteine is used for paracetamol poisoning. Slow intravenous infusion and chloride diuresis along with amifostine can limit cisplatin induced nephrotoxicity.