All are true about nephronophthisis except:: (A) Interstitial fibrosis, (B) Coical tubular hyperophy, (C) Cysts in the medulla, (D) 20% cases are non-familial
Answer is B. 2 types of cystic disease affecting the renal medulla are : 1. Medullary sponge kidney Relatively common Usually innocuous condition Associated with nephrolithiasis 2.Nephronophthisis- Medullary cystic disease complex Associated with renal dysfunction. Cause of chronic kidney disease that usually begins in childhood. Coical tubulointerstitial damage and not hyperophy occurs in nephronophthisis.