Gene instability associated with malignancy is seen in -: (A) Klippel fiel syndrome, (B) Ataxia telangiectasia, (C) Marfan'g syndrome, (D) EDS
Answer is B. Ans. is 'b' i.e., Ataxia telangiectasiaSyndromes of defective DNA repair have such a high level of chromosomal instability that they are known as chromosome-breakage syndromes or chromosomal instability syndromes.