A young male patient presented with prolonged bleeding time. You take a detailed history and ask the patient for intake of NSAIDs as these can prolong the bleeding time. The patient refuses the intake of any form of NSAIDs. No other drug history was obtained. All of the following drugs can prolong bleeding time except: (A) Cephalosporins, (B) Multivitamins containing Vitamin K, (C) Methylxanthines, (D) Anti-depressants
Answer is B. Ans. (B) Multivitamins containing Vitamin K(Ref: Goodman and Gilman 12/e p1806)Vitamin K is involved in activation of clotting factors II, VII, IX and X. It thus, decreases the risk of bleeding.