The main cytokine, involved in erythema nodosum leprosum (ENL) reaction is-: (A) lnterleukin - 2, (B) Interferon - gamma, (C) Tumor necrosis factor - alpha, (D) Macrophage colony stimulating factor
Answer is C. The main cytokines responsible for type 2 leprosy reactions are interleukin 1 and tumour necrosis factor alpha. iadvl textbook of dermatology, page 2049