Riociguat is used in the treatment of:: (A) Gouty ahritis, (B) Rheumatoid ahritis, (C) Chronic thromboembolic pulmonary hypeension, (D) Obesity
Answer is C. Riociguat a soluble guanylate cyclase stimulator. It is the only therapy approved by USFDA for inoperable CTEPH (Chronic thromboembolic pulmonary hypeension). Best treatment for operable cases is pulmonary thromboendaerectomy done in expe centres. Reference: Ghofrani HA, D'Armini AM, Grimminger F, Hoeper MM, Jansa P, Kim NH, Mayer E, Simonneau G, Wilkins MR, Fritsch A, Neuser D, Weimann G, Wang C; CHEST-1 Study Group. Riociguat for the treatment of chronic thromboembolic pulmonary hypeension. N Engl J Med. 2013; 369:319-329