What will happens to structure of alpha-helix if L-alanine is replaced by d-alanine alternatively: (A) Change in optical activity, (B) Interruption of structure, (C) Increased stereoisomerism, (D) Increased stability
Answer is B. Ans. is 'b' i.e., Interruption of structureD-amino acid would interrupts an a-helix made of L-amino acid.D-amino acid substitution in a-helix causes a local change in structure and flexibility at the substituted site, which leads to destabilization