Type of hereditary hemorrhagic telangiectasia commonly associated with ALK-1 mutation is:: (A) Type 1, (B) Type 2, (C) Type 3, (D) Type 4
Answer is B. B i.e. Type 2Ref: Genetic Home ReferenceExplanation:Hereditary Hemorrhagic Telangiectasia (HHT or Osler-Weber-Rendu Syndrome)Inherited disorder characterized by malformations of various blood vessels (vascular dysplasia), potentially resulting in bleeding (hemorrhage).There are totally 6 types till date.Chronic nose bleeding is usually the first sign*.Genetics.TypeMutationHHT 1ENG geneHHT 2ALK 1 geneHHT 3Unidentified gene in Ch 5 (putative)HHT 4Ch 7p14