Which one of the following anaesthetic agents causes a rise in the Intracranial pressure:: (A) Sevoflurane, (B) Thiopentone sodium, (C) Lignocaine, (D) Propofol
Answer is A. Intracranial pressure is increased at high inspired concentration of sevoflurane but this effect is minimal over the 0.5-1MAC range. Ref: Textbook of Anaesthesia By Aitkinhead, 4th Edition, Page 159; Clinical Anesthesiology By Morgan, 3rd Edition, Pages 138, 558