Hand and foot syndrome is an adverse effect of:: (A) 5-Fluorouracil, (B) Bleomycin, (C) Etoposide, (D) Actinomycin D
Answer is A. Capecitabine and 5-FU can cause hand and foot syndrome. Diarrhea is the most common adverse effect of 5-FU. 5-FU can also cause bone marrow suppression. Drugs commonly implicated are: Capecitabine 5-Fluorouracil Cytarabine Pemetrexed Doxorubicin