Which of the following is not used in the treatment of pulmonary hypertension?: (A) Calcium channel blockers, (B) Alpha blockers, (C) Prostacyclins, (D) Endothelin receptor antagonists
Answer is B. Ans. (B) Alpha blockers(Ref: CMDT 2010/381)Management of Idiopathic Pulmonary Hypertension*If the patient responds to vasodilators, then calcium channel blockers (including amlodipine, diltiazem, and nifedipine) are the first-line therapy.Other drugs that can be used are:-Phosphodiesterase inhibitors (e.g. sildenafil)-Prostacyclin analogs (e.g. epoprostenol)-endothelin receptor blockers (e.g. bosentan)