Rupa Devi age 65 year old female with ovarian cancer is being treated with cisplatin based chemotherapy. All of the following are used to limit the toxicity of cisplatin except: (A) N-acetylcycteine, (B) Slow rate of infusion, (C) Chloride diuresis, (D) Amifostine
Answer is A. Ref-harrison 18/e p697 N-acetylcycteine used for Paracetamol poisoning whereas slow intravenous infusion and chloride diersis with amifostine can limit cisplatin induced nephrotoxicity