Myaesthenia gravis is associated with:: (A) Decreased acetylcholine at nerve endings, (B) Decreased myosin, (C) Absent troponin C, (D) Decreased myoneural junction transmission
Answer is D. Answer is D (Decreased Myoneural junction transmission): The primary defect in Myaesthenia gravis is decreased transmission across the myoneural junction due to decrease in the number of Acetylcholine receptors. The fundamental defect is Myaesthenia gravis is a decrease in the number of Acetylcholine Receptors at the postsynaptic muscle membrane, which results in decreased efficiency of neuromuscular transmission' -- Harrison