Which amongst the following statements are true regarding Acute Fatty liver of Pregnancy?: (A) Occurs due to LCHAD deficiency (long-chain hydroxyl acyl coenzyme A dehydrogenase), (B) Macrovascular steatosis with peripoal sparing, (C) Increase in fibrinogen, ammonia and SGOT, (D) Most of the cases are asymptomatic
Answer is A. Acute Fatty liver of Pregnancy = Acute Metamorphosis = Acute yellow Atrophy Abnormal fatty acid oxidation LCHAD deficiency present in foetus.(long-chain hydroxyl acyl coenzyme A dehydrogenase) Microvascular steatosis with peripoal sparing Greasy soft yellow liver Complications--hypoglycaemia, hepatic encephalopathy, coagulopathy, renal failure, moality (10-75%), and increased risk of PIH. Treatment--fresh frozen plasma, cryoprecipitate, platelets, and blood.