Which of the following is involved in transpo of large molecules from cytoplasm to the cell nucleus?(2018): (A) Calthrin, (B) Caveolin, (C) Flotillin, (D) Impoins
Answer is A. Clathrin mediated endocytosis is responsible for the internalization of many receptors and the ligands bound to them--including, for example, nerve growth factor(NGF). Rafts and caveolae,are involved in cholesterol regulation and transcytosis. Ref:- Ganong, pg num:-46, 47