Sirolimus is more likely than cyclosporine to cause :: (A) Hypertension, (B) Osteoporosis, (C) Renal insufficiency, (D) Thrombocytopenia
Answer is D. Cyclosporine and tacrolimus cause nephrotoxicity as an adverse effect.
Sirolimus (rapamycin) results in bone marrow suppression and thus may cause anemia, thrombocytopenia and leu­kopenia.