A newborn baby was born with phocomelia. It results due to which drug taken by mother during pregnancy?: (A) Tetracycline, (B) Thalidomide, (C) Warfarin, (D) Alcohol
Answer is B. Thalidomide disaster (1958-61) resulting in thousands of babies born with phocomelia (seal-like limbs) and other defects focused attention to this type of adverse effect. Tetracyclines cause discolored and deformed teeth, retarded bone growth in children Warfarin causes depressed nose; eye and hand defects, growth retardation in childrenAlcohol causes low IQ baby, growth retardation, fetal alcohol syndrome in children Ref; KD Tripathi pharmacology 7 th editon (page no; 89)