Cafe au lait macules are seen in: (A) Von Reklinghausen's neurofibromatosis, (B) Albright's syndrome and Bloom's syndrome, (C) All of the above, (D) None of the above
Answer is C. Bloom syndrome' is characterized by a high frequency of breaks and rearrangements in an affected person's chromosomes. The affected person characteristically develops a facial rash after exposure to sun. Other clinical features include a high pitched voice, distinct facial features such as Long, narrow face, micrognathism of mandible, and pigmentation changes of skin with cafe aulait spots.