Which one of the following preferentially activates plasminogen bound to fibrin and avoids the systemic lytic state -: (A) Streptokinase, (B) Aminocaproic acid, (C) Tranexamic acid, (D) Alteplase
Answer is D. Ans. is 'd' i.e., Alteplase o Alteplase, Reteplase and tenecteplase are recombinant t-PA. These are nonantigenic. They activate fibrin bound plasminogen only. o Streptokinase activates both free as well as fibrin bound plasminogen.