The Haemophilus influenzae vaccine contains which of the following: (A) Lipopolysaccharide (LPS), (B) Live attenuated H. influenzae, (C) Polypeptide antigens containing D-glutamate, (D) Polyribitol phosphate antigens
Answer is D. Polysaccharide vaccine Haemophilus influenzae type b is a bacterium with a polysaccharide capsule; the main component of this capsule is polyribosyl ribitol phosphate (PRP). Anti-PRP antibodies have a protective effect against Hib infections. Thus, purified PRP was considered a good candidate for a vaccine Ref ananthnarayana microbiology textbook 8/e