Gene silencing means a gene which would be expressed under normal circumstances is switched off by cell machinery. Which one of the following cellular components is not involved in gene silencing?: (A) Micro-RNA, (B) Double stranded RNA, (C) Ribosomal RNA, (D) Si RNA
Answer is C. Ans. (c) Ribosomal RNA(Ref: Robbins 9th/pg 172-173)Two of the leading methods of gene silencing are RNA interference (RNAi), Si RNA and antisense oligonucleotides (ASOs), ds RNAIt does not affect ribosomal RNA