Which of the following statements about terbinafine is FALSE?: (A) Its activity is restricted to dermatophytes, (B) It is effective in onychomycosis, (C) It is not effective in cryptococcal meningitis, (D) It is kunlikely to produce anti-androgenic side effects
Answer is D. (Ref: KDT 6/e p765) Terbinafine is a CIDAL drug against dermatophytes. It can be administered orally or can be applied topically. It acts by inhibiting the enzyme squalene epoxidase resulting in accumulation of toxic squalene.