Which of the following is NOT associated with elevation of prostatic specific antigen?: (A) Acute prostatitis, (B) BPH, (C) Prostatic intraepithelial neoplasm, (D) Prostatic needle biopsy
Answer is C. Prostatic Intraepithelial Neoplasia ( PIN) is a precancerous condition; not detected by rectal examination, TRUS , or MRI; does not cause rise in PSA level . It is usually identified after TURP for BPH with final histology or by prostatic biopsy.Reference: page1048 SRB&;s manual of surgery 5th edition