Maintainance dose of drug is dependent on ?: (A) Half life, (B) Volume of distribution, (C) Total body concentration, (D) Loading dose
Answer is A. Ans. is 'a' i.e., Half life Loading dose is governed by volume of distribution. Maintenance dose is governed by clearance or P/2. The drug with sho t1/2 with loading and maintenance dose concept - Lignocaine.