Which glycogen storage disease does not affect muscles?: (A) Type 1, (B) Type 2, (C) Type 3, (D) Type 4
Answer is A. a. Type 1(Ref: Nelson's 20/e p 715-725, Ghai 8/e p 655-657)Type 2 Pompe disease predominantly involves muscles, while type I GSD involves liver.Although type 2 and type 3 GSD are predominantly liver glycogenoses, skeletal muscle involvement may also be seen.