Which of the following is NOT affected in Rh isoimmunization?: (A) Anti C, (B) Anti E, (C) Anti-Lewis, (D) Anti D
Answer is C. Anti-Lewis and anti-I antibodies are not associated with fetal hemolytic disease. It differs from all other antigens in that they are not synthesized in RBC membrane, but absorbed into it. Ref: Obstetrics and Gynecology By Charles R. B. Beckmann, American College of Obstetricians and Gynecologists, 2010, Page 197.