"Anhedonia" seen in schizophrenia is linked to which of the following neurotransmitter abnormality?: (A) Serotonin, (B) Dopamine, (C) Glutamate, (D) GABA
Answer is B. Anhedonia refers to the reduced ability to experience pleasure.In animal models severe stress causes nucleus accumbens dopamine neurons to become insensitive to CRF (Coicotropin-Releasing Factor), resulting in reduced dopamine release and increased anhedonia.(Ref: Kaplan and Sadock&;s synopsis of psychiatry Pg 290)