A cardiologist wants to study the effect of an antihypertensive drug. He notes down the initial systolic blood pressure (mmHg) of 50 patients and then administers the drug on them. After a week's tretment, he measures the systolic blood pressure again. Which of the following is the most aproprate statistical test of significance to test the statistical significance of the change in blood pressure -: (A) Paired t-test, (B) Unpaired or independent t-test, (C) Analysis of variance, (D) Chi-square test
Answer is A. In the given question, a cardiologist wants to study the effect of an anti-hypertensive drug. So he will compare mean BP of 50 patients before and after administering the drug. Thus Paired t-test will be most appropriate test of significance