Which of the following stain is used to detect the capsule of Cryptococcus neoformans in a CSF sample?: (A) Grams stain, (B) Zeihl neelson stain, (C) India ink preparation, (D) Methanamine-Silver stain
Answer is C. Capsule of cryptococcus neoformans in a CSF sample is best seen by India ink preparation. Gomori methanamine stain, PAS stain and Alcian blue stain are also used in identifying this organism. Ref: Handbook for Zoonotic Diseases of Companion Animals By Glenda Dvora, 1st Edition, Pages 108-9