Life threatening intravascular hemolysis occur with sepsis due to which organism?: (A) Clostridium perfringens, (B) Mycoplasma pneumonia, (C) Pseudomonas, (D) Klebsiella
Answer is A. Clostridium perfringens sepsis leads to life threatening intravascular hemolysis due to lecithinase activity. It occurs following open wounds, septic aboion, or due to a contaminated blood unit. Other infections causing hemolytic anemia: Malaria Shiga toxin-producing E. coli O157:H7