Among the following which is a feature of testicular feminization syndrome .: (A) XX pattern, (B) Commonly reared as male, (C) Well formed female internal genitalia, (D) High testosterone levels
Answer is D. High testosterone levels In Testicular Feminization Syndrome Genotype -- 46XY Gonads -- Testis (intrabdominal) Phenotype -- Female Internal Genitalia -- Vagina is sho. uterus absent. They are reared as female. Testosterone levels may be Low / Normal / High. Lab investigation : Testosterone levels may be Normal/High/Low depending on the degree of androgen resistance and the contribution of estradiol to feedback inhibition of the hypothalamus pituitary axis. Harrison 17/e, p 2344 LH levels are high (due to insensitivity of Pituitary and hypothalamus to testosterone) but FSH levels are Normal.