Hypercoagulation in Nephrotic syndrome is caused by:: (A) Loss of Antithrombin III, (B) Decreased Fibrinogen, (C) Decreased Metabolism of Vitamin K, (D) Increase in protein C
Answer is A. Answer is A (Loss of Antithrombin III) Loss of Antithrombin III contributes to the hypercoagulable state in Nephrotic syndrome `A hypercoagulable state frequently accompanies severe nephrotic syndrome due to urinary losses of antithrmbin reduced serum levels of protein C and S, hyperfibrinogenemia and enhanced platelet aggregation'