Burkitts lymphoma shows which translocation-: (A) t (8-14), (B) t (11-14), (C) t(14-18), (D) t (14-21)
Answer is A. Cytogenetic abnormalities in the tumor cells of Burkitt&;s lymphoma is t (8;14) ,and t (8;22) involving MYC gene on chromosome 8 witho overexpression of MYC protein having transforming activity. Reference textbook of Pathology 6th edition Author Harsha Mohan page number 378