Best test for diagnosis of Carcinoid tumor:: (A) 24 hour urinary 5H.I.A.A, (B) 24 hour catecholamines, (C) 24 hour vaniylmandelic acid levels, (D) 24 hour metanephrine levels
Answer is A. Ans. (a) 24 hour urinary 5H.I.A.ARef: Harrison 19th ed. 1564-65* 5-HLAA is the major urinary metabolite of serotonin, a ubiquitous bioactive amine. Serotonin, and consequently 5-HLAA, are produced in excess by most carcinoid tumors, especially those producing the carcinoid syndrome of flushing, hepatomegaly, diarrhea, bronchospasm, and heart disease.