Nanovalent vaccine offers protection against which type of HPV viruses?: (A) 6, 8, 10, 11,31,33, 45, 52, 58, (B) 6, 11, 16, 18,31,33, 45, 52, 58, (C) 6, 11, 16, 18, 31, 35, 45, 52, 58, (D) 6, 11, 16, 18,31,32, 33, 34
Answer is B. ANS. BHPV vaccine:* Cervarix: Bivalent--16 and 18* Gardasil: Quadrivalent: 6, 11, 16 and 18* Nanovalent vaccine: 6, 11, 16, 18, 31, 33, 45, 52, 58* 3 doses: 0, 2, and 6 months* 0.5 mL given IM.Images in Pap smearThree types of cells in Pap smear:1. Superficial: Red cells--estrogen dependent2. Intermediate: Greenish-blue--progesterone dependent3. Parabasal: Blue--does not respond to estrogen/progesteroneImportant points in Pap smear:1. In menopause, there is excess parabasal cells.2. Basal cells never occur in Pap smear, if present it indicates erosion.