On colonoscopy which of the following is highly malignant -: (A) Single pedunculated polyp, (B) Multiple flat polyp about hundreds, (C) Multiple pedunculated polyp, (D) Solitary flat polyp
Answer is B. • Also referred to as Bannayan-Zonana syndrome, Ruvalcaba-Riley smith syndrome, and Bannayan-Riley-Ruvalcaba syndrome.
• Characterized by hamartomatous polyposis and OLD HM-2.
OLD HM-2 :
• Ocular abnormalities, Lipomas, Developmental abnormalities.
• Hashimoto’s thyroiditis, Hyperpigmentation of penis.
• Macrocephaly, Mental retardation.
• No increased risk of colorectal carcinoma, other gastrointestinal or extraintestinal malignancy.