A7 year old presents with fever, weight loss. On examination he was pale and had significant lymphadenopathy. Bone marrow histology is as given below. What is the most probable diagnosis?: (A) ALL, (B) AML, (C) Aplastic anaemia, (D) juvenile myelomonocyticleukemia
Answer is A. Ans. (a) ALL(Ref: R 9/611)The picture is that of a lymphoblast. Lymphoblasts will be 3-4x larger than a mature RBC, High nuclear to cytoplasmic ratio, Round Nucleus with immature chromatin (not clumped), Prominent nucleoli, Cytoplasm is scant, light blue and lacks granules