C terminal end of androgen receptor is concerned with: (A) Ligand binding, (B) Increasing biological half life, (C) Increasing the affinity of receptor to DNA, (D) Increasing the level of transcription
Answer is A. Activation function 2 (AF-2), responsible for agonist-induced activity (activity in the presence of bound agonist)Ref: DM Vasudevan, 7th edition, page no: 669