All of the following are recognized effects of combined oral contraceptives except: (A) Breakthrough bleeding, (B) Decreased risk of endometrial cancer, (C) Increased risk of ischemic stroke, (D) Increased risk of colon cancer
Answer is D. Adverse effects of OCP- breakthrough bleeding, coronary and cerebral thrombosis resulting in MI or stroke, increased incidence of genital carcinoma-like vaginal, cervical, breast cancers. It has a protective effect against endometrial carcinoma due to progesterone (Ref.Essentials of medical pharmacology TD Tripathi 7th edition page no.325,326)