All of the following are invasive carcinoma breast except: (A) Comedo carcinoma, (B) Colloid carcinoma, (C) Lobular carcinoma in situ, (D) Medullary carcinoma
Answer is A. The comedo subtype is distinctive and is characterized by cells with high-grade nuclei with extensive central necrosis.The name derives from the toothpaste-like necrotic tissue that extrudes from transected ducts on application of gentle pressure ref : Robbins Basic Pathology, 9E,page-710