Dicumarol is a drug that impairs the utilization of vitamin K by the liver. Dicumarol therapy would decrease the plasma concentration of which of the following procoagulants: (A) Prothrombin, (B) Fibrinogen, (C) Factor VIII, (D) Factor V
Answer is A. Factor II is also called as Prothrombin, it is a vitamin K dependent clotting factor. Warfarin acts by inhibiting Vitamin K Epoxide Reductase Complex(VKORC) subunit 1 Ref: Ganong 25th ed/page 567