Baezomib is -: (A) Proteosome inhibitor, (B) DNA methyl transferase inhibitor, (C) Tyrosine kinase inhibitor, (D) Histone deacylase inhibitor
Answer is A. Ans. is 'a' i.e., Proteosome inhibitor Proteosome inhibitors o Transcription factor NFKB is associated by an inhibitor IKB. o IKB is degraded by proteosomes. o Inhibition of proteosome prevents degradation of IKB which inhibits the overactivity of NFKB. o Proteosome inhibitor (Baezomib) is used in multiple myeloma.