All are true about familial male limited precocious pubey, EXCEPT:: (A) It is also called Testotoxicosis, (B) Autosomal dominant condition, (C) Testosterone and LH levels are elevated, (D) Flutamide can be used for treatment
Answer is C. Familial male limited precocious pubey is also called testotoxicosis. FACTS : It is an autosomal dominant disorder It presents as premature androgenization of boys Testosterone is elevated, LH is suppressed in the condition Treatment options : 1. Ketoconazole - Inhibits testosterone synthesis. 2. Flutamide - Used as an androgen receptor antagonist. 3. Anastrazole - Is a useful aromatase inhibitor. Ref: Harrison, Edition - 18, Page - 3015