The diphtheria toxin has an affinity for all the following tissues EXCEPT: (A) Myocardium, (B) Brain, (C) Adrenals, (D) Liver
Answer is D. The diphtheria toxin is the sole virulence factor of C. diphtheriae. Responsible for both local effects and systemic complications. It is encoded by a lysogenic beta-prophage. It inhibits mammalian protein synthesis (ribosomal function) ADP ribosylation of EF-2 It has a special affinity for myocardium, adrenals and nerve endings