which of the following is a SARI: (A) miazapine, (B) milnacipran, (C) clozapine, (D) nefazadone
Answer is D. SARI * IMPOANCE antidepressant with good sleep, no sexual problems and no GI side effects. It was thought this would replace SSRI but dint do well because of notorious side effects * MECHANISM Serotonin antagonist and reuptake inhibitor * DRUGS Trazodone Nefazodone * USE low dose trazodone is used as a hypnotic * SIDE EFFECTS Trazodone----------- priapism Nefazodone ---------hepatotoxicity Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pf no. 955