Drug contraindicated in hyperiglyceridemia: (A) Fibrates, (B) Simvastatin, (C) Niacin, (D) Cholestyramine
Answer is D. Bile acid binding resins like cholestyramine causes increase in triglycerides and are thus contraindicated in patients with hyperiglyceridemia due to risk of development of pancreatitis. Statins - decrease LDL and increase HDL Niacin - decrease LDL and triglyceride, maximum increase in HDL Fibrates - decrease triglyceride, decrease LDL.