Which one of the following is NOT true about chemical mediators:: (A) Leukotrienes are formed by lipo-oxygenase pathway, (B) Histamine is a preformed chemical mediator, (C) Prostaglandin causes vasoconstriction at the site of inflammation, (D) Thromboxane A2 is associated with platelet aggregation
Answer is C. Leukotrienes are formed by Lipo-oxygenase , Whereas, prostaglandins are formed by cyclo-oxygenase. PGs causes vasodilation.