Which is the best treatment in a case of PNH presenting with black colour urine?: (A) Eculizumab, (B) Rituximab, (C) Infliximab, (D) Prednisolone
Answer is D. Ans. D. PrednisoloneTreatment:Best Initial treatment to control Hemolysis = PrednisoloneBest treatment = BMTBest treatment to prevent chronic hemolysis or clot formation = Eculizumab:Eculizumab is a monoclonal antibody that specifically binds to the complement protein C5, thus inhibiting terminal complement mediated intravascular hemolysis in PNH patients.