All are true about fibrolamellar HCC except:: (A) AFP is not raised, (B) Recurrence is common, (C) Raised neurotensin levels, (D) Well demarcated and encapsulated
Answer is D. Ans. (d) well demarcated and encapsulatedRef: Sabiston 19/e p 1458Features of Fibro lamellar HCC:* MC in Young adults (M = F)* No H/o Cirrhosis* Pathology: Well demarcated, Non encapsulated, Central Fibrotic scar* High resectable rate* Slow growth, Better prognosis* AFP is normal* Neurotensin and Vit- B12 Binding Globulin are elevated* Recurrence is common after resection (80% recur)* Lymph nodes ++ predict worst outcome