Most Common extranodal site of Lymphoma in HIV is?: (A) CNS, (B) GIT, (C) Retroperitoneum, (D) Mediastinum
Answer is A. Ans. (a) CNS(Ref: Harrison 18th/pg Chapter 189)Lymphoma in HIV90% of lymphomas in HIV are B cell in phenotype; more than half contain EBV DNA.Immunoblastic lymphomas account for 60% of the cases of lymphoma in patients with AIDS.Primary CNS lymphoma accounts for 20% of the cases of lymphoma in patients with HIV infection.Most common extranodal site involved in Lymphoma in HIV is the CNS, which is involved in one-third of all patients with lymphoma.