Mechanism of action of metoclopramide:: (A) Increase the lower esophageal sphincter, (B) Decrease the acid secretion, (C) Increase gastric peristalsis, (D) Ulcer healing agent
Answer is A. Ans. A. Increase the lower esophageal sphincterMetoclopramide is prokinetic drug. It acts on D2 and 5Ht3 receptor. There is increase in acetylcholine level and there is increase in LES and gastric motility.