Montelukast mechanism of action is?: (A) Competitive inhibitor of leukotriene synthesis, (B) Inhibits alpha receptor, (C) Beta receptor agonist, (D) Non-competitive inhibitor of leukotriene synthesis
Answer is A. ANSWER: (A) Competitive inhibitor of leukotriene synthesisREF: Goodman and Gillman's 11TH edition p. 478"Zafirlukast and Montelukast are leukotriene receptor antagonists. Leukotriene-modifying drugs act either as competitive antagonist of leukotriene receptors or by inhibiting the synthesis of leukotriene"