A small girl with neuropsychiatry symptoms has a habit of licking paint in walls .Symptoms due to inhibition of: (A) ALA dehydratase, (B) ALA synthase, (C) Heme oxygenase, (D) CPG oxidase
Answer is A. It is a case of lead poisoning. Specifically, lead decreases heme biosynthesis by inhibiting aminolevulinic acid dehydratase (ALAD) and ferrochelatase. patients presents with microcystic hypochromic anemia.