The protein that anchors both actin and titin at Z lines is?: (A) Myomesin, (B) Nebulin, (C) a-actinin, (D) Myosin
Answer is C. Ans. (c) a-actinin(Ref: Gautel et al. Journal of Experimental Biology (2016) 219, 135-145)a-Actinin anchors both titin and actin filaments at Z linesMyomesin and obscurin are the myosin cross linking protein that attaches myosin at M lineNebulin is an acting binding protein that regulates the length of thin filaments