Sandhoff's disease is d/t absence of which enzyme?: (A) Beta-hexosaminidase, (B) Beta-glucuronibase, (C) Aryl sulphatase, (D) Alpha galactosidase
Answer is A. It is a lipid storage disease.Due to deficiency of hexaminidase.Leads to accumulation of globoside (Table;14.4)Ref: DM Vasudevan, 7th edition, page no: 193