Which of the following anti-diabetic drugs are associated with weight gain?: (A) Acarbose, (B) Metformin, (C) Sitagliptin, (D) Pioglitazone
Answer is D. Pioglitezone Only one thiazolidinedione, pioglitazone is currently available in india C/I in liver and hea failure Selective agonist for PPAR ? ( peroxisome proliferator activated receptor ?) Lower serum triglyceride level ,raises HDL level Reverse insulin resistance