Organophosphates bind to: (A) Anionic site of AChEs, (B) Esteratic site of AChEs, (C) Ach, (D) None
Answer is B. (Ref: KDT 6/e p99-100) The active region of Acetylcholinesterase (AChE) has two sites i.e. an anionic site and an esteratic site. Anticholinesterase poisoning like Organophosphate compounds binds to esteratic site of AChE.