Cataract in diabetic patients is because of the accumulation of sorbitol in the lens. The enzyme responsible for this is –: (A) Hexokinase, (B) NADPH+ dependant aldolase reductase, (C) Glucokinase, (D) Phosphofructo isomerase
Answer is B. NADPH+ dependent aldolase reductase reduces excessive glucose to sorbitol and intracellular accumulation of sorbitol causes osmotic changes resulting in cataract development.