Pernicious anemia associated with ?: (A) Gastric pathology, (B) Renal pathology, (C) Esophageal pathology, (D) Oral pathology
Answer is A. Ans. is 'a' i.e., Gastric Pathology Anemias of Vitamin B12 Deficiency: Pernicious Anemia Pernicious anemia is a specific form of megaloblastic anemia caused by an autoimmune gastritis that impairs the production of intrinsic factor, which is required fir vitamin B12 uptake from the gut. Histologically, there is a chronic atrophic gastriti smarked by loss of parietal cells, prominent infiltrate of lymphocytes and plasma cells, and megaloblastic changes in mucosal cells.