Earliest changes of neoplastic transformation as seen at a microscope level is called: (A) Hyperplasia, (B) Metaplasia, (C) Dysplasia, (D) Carcinoma insitu
Answer is C. dysplasia is the loss of uniformity of individual cells as well as their architectural orientation carcinoma in situ dysplasia changes are marked but , lesion remains confirmed to normal tissue; pre invasiveneoplasm basement membrane is intact anaplasia is complete lack of differentiation of cells both morphologically and functionally