Which of the following amino acid can be synthesised from a glycolytic intermediate in human body?: (A) Aspaate, (B) Glutamate, (C) Histidine, (D) Serine
Answer is D. Serine is a dietary non-essential amino acid since it can be synthesised from the glycolytic intermediate 3-phosphoglycerate. Oxidation of 3-phosphoglycerate by a dehydrogenase, conves it to 3-phosphohydroxypyruvate. Transamination and subsequent dephosphorylation then form serine.