Which of the following is true regarding non-specific interstitial pneumonia?: (A) Honeycombing on CT scan, (B) More common in male smokers, (C) Fibroblastic foci are characteristic, (D) Most often associated with connective tissue disease
Answer is D. Non-specific interstial pneumonia (NSIP) Etiology most often a/w connective tissue disorder can be idiopathic C/F More likely in elderly female (non-smoker) Dyspnea, cough M/E Cellular pattern or Fibrosing pattern No fibroblastic foci No honey combing No granulomas or hyaline membranes B/L reticular opacities on HRCT present Cases with cellular pattern have a better prognosis.