All of the following may be associated with Beta 2 agonist treatment, EXCEPT:: (A) Hyperkalemia, (B) Hyperglycemia, (C) Detrusor relaxation, (D) Relaxation of gut and bronchial muscles
Answer is A. Beta 2 agonists stimulate the uptake of potassium into the cells which results in hypokalemia and not hyperkalemia as mentioned above. Beta 2 agonists administered in the parenteral form or as nebulisation can be used in the management of hyperkalemia by promoting cellular intake. Ref: Harrison's Textbook of Internal Medicine 16th Edition, Pages 263; Goodman and Gilman's The Pharmacological Basis of Therapeutics, 11th Edition, Pages 143-44, 247; K D Tripathi Textbook of Pharmacology, 5th Edition, Pages 109-111