Which one of the following drugs exacerbate reflux esophagitis: (A) Cisapride, (B) Chlorpropamide, (C) Theophylline, (D) Metoclopramide
Answer is C. Drugs that can increase acid reflux and worsen GERD include: Anticholinergics Tricyclic antidepressants Calcium channel blockers Nitrates Opioids Progesterone Quinidine Benzodiazepines Theophylline ref - Harrisons internal medicine 20e pg2215,2219