Which one of the following statements is false regarding vincristine -: (A) It is an alkaloid, (B) Its use is associated with neurotoxicity, (C) It does not cause alopecia, (D) It is a useful drug for induction of remission in acute lymphoblastic leukaemia
Answer is C. Ans. is 'c' i.e., It does not cause alopecia o Vincristine belongs to the plant alkaloid group of anticancer. o Useful for inducing remission in childhood ALL (not useful in maintenance therapy) o It can also be used for pediatric solid tumors (Wilm's tumor, neuroblastoma, rhabdomyosarcoma) and lymphomas. o Prominent adverse effects? o Peripheral neuropathy Alopecia SIADH