Which one of the following inhalational anesthetics is most likely to cause fluoride ion nephrotoxicity: (A) Methoxyflurane, (B) Enflurane, (C) Halothane, (D) Isoflurane
Answer is A. Methoxyflurane causes dose-related nephrotoxicity because of the inorganic fluoride that resulted from the metabolism of this anaesthetic.Basics of Anaesthesia 7e pg 86