Which of the following is a feature of Vit B12 deficiency anemia?: (A) Hypersegmented neutrophils, (B) Macro-ovalocytes, (C) Megaloblastic anemia, (D) All of the above
Answer is D. Clinical manifestations of Vitamin B12 deficiency: Haematological: Macro-ovalocytes, Hypersegmentation of neutrophils. Neurological: Demyelination in peripheral nerves and spinal cord B12 deficiency leads to megaloblastic anemia due to folate trap The peripheral smear given below shows hypersegmented neutrophil and macro-ovalocytes