Cholesterol present in LDL :: (A) Represents primarily cholesterol that is being removed from peripheral cells., (B) Binds to a receptor and diffuses across the cell membrance., (C) On accumulation in the cell inhibits replenishment of LDL receptors., (D) When enters a cell, suppresses activity of acyl-CoA: cholesterol acvtranferase ACAT.
Answer is C. C i.e. On accumulation in the cell inhibits replenishment of LDL receptors.