Drug of choice to treat Toxoplasmosis in first-trimester of pregnancy is: (A) Spiramycin, (B) Pyrimethamine-Sulphonamide, (C) Atovaquone, (D) Ivermectin
Answer is A. Compound Drug class Route Mechanism of action Clinical use Comment Spiramycin Macrolide Oral Blocks proteinsynthesis Toxoplasmosis Used to treat pregnantwomen Ref : Paniker's textbook of Medical Parasitology Pgno : 241,242