Which of the following sites is responsible for the amnestic defect in Wernicke's Korsakoff syndrome:: (A) Mamillary body, (B) Thalamus, (C) Periventricular Grey matter, (D) Hippocampus
Answer is B. Answer is B (Thalamus): The Amnestic effect in Wernicke's Korsakoff Syndrome is related to lesions in the dorso-medial nuclei of the thalamus. `Lesions in the dorsomedial nucleus of the thalamus seem to be the best correlate of the memory disturbance and confabulation' - Robbins