Cytogenetics for synol cell sarcoma is: (A) t(X:18), (B) t(17,9), (C) t(9,22), (D) t(11,14)
Answer is A. Most synol sarcoma show a charecteristic(x:18) translocation that produces a fusion gene encoding a chimeric transcription factor. They usually devolop in deep soft tissues aroundcthe knee,occuring in age groups 20-40s Robbins basic pathology 9th edition page no 795,heading=synol sarcoma