A child develops blisters on exposure to sunlight' Irregular dark spots on the skin are also found' He is very likely to have a defect in which of the following mechanisms?: (A) Nucleotide excision repair, (B) Mismatch repair, (C) Recombination repair, (D) Thymine dimers
Answer is A. The child in question is presenting with features of xeroderma pigmentosa, due to defect in nucleotide excision repair