In SCID, what type of DNA repair is defective?: (A) Double strand break repair, (B) Nucleotide excision repair, (C) End Joining Repair, (D) Mismatch repair
Answer is C. Defects in Double-Strand Break Repairs: Defects in Single-Strand Break Repairs: Non-Homologous End Joining Repair (NHEJ) SCID (Severe Combined Immunodeficiency Disease) (RS-SCID) Radiation sensitive Severe Combined Immunodeficiency Disease Nucleotide excision Repair (NER) Xeroderma Pigmentosa Homologous Repair (HR) Bloom syndrome Werner syndrome Breast cancer Base Excision Repair (BER) MUTYH associated Polyposis Mismatch Repair (MMR) HNPCC (Hereditary Non-Polyposis Colorectal Cancer)