In pemphigus circulating antibodies attack:: (A) Desmoglein 1&2., (B) Desmoglein1&3., (C) Desmoglein1&4., (D) Desmoglein2&4.
Answer is B. Pemphigus

Is a skin and mucous membrane disease with autoimmune etiology.
Characterized histologically by intradermal blisters circulating IgG (IgG1 and IgG4) antibody against keratinocyte cell surface (attack Desmoglein 1 and 3).