All are the risk factors for endometrial carcinoma except :: (A) Multiparity, (B) Obesity, (C) Early menarche, (D) Unopposed estrogen therapy
Answer is A. Pathology behind endometrial cancer is unopposed estrogen exposure to endometrium Multiparity is a protective factor Unopposed oestrogen or high level of oestrogen Chronic anovulation, PCOD Familial predisposition Tamoxifen Obesity, hypeension, diabetes Feminizing ovarian tumour Low parity Late menopause Reference: Shaw's Textbook of Gynaecology 16th edition page no 508