Poor prognostic factor for ALL is: (A) Female sex, (B) Leukocyte factor < 50,000, (C) Age greater than 1 year, (D) Hypodiploidy
Answer is D. Hypodiploid acute lymphoblastic leukemia is the chromosome mutation of leukemic cells with 45 chromosomes or less. It has been determined that the prognosis of hypodiploid is much less than standard acute lymphoblastic leukemia. The lower the chromosome count, the lower the survival rate.