True statement regarding development of drug resistance in MRSA is ?: (A) Results due to penicillinase enzyme production, (B) Occurs due to change in penicillin binding proteins, (C) Chromosome mediated, (D) Treated with amoxicillin + clavulanic acid
Answer is B. Methicillin resistance occurs due to altered PBPS, thus no penicillin, (Infact no beta-lactam antibiotic) is useful against methicillin-resistant Staphylococcus aureus (MRSA) infections.