Relative to filgrastim (G-CSF), sargramostim (GM-CSF): (A) Has greater oral bioavailability, (B) Is more likely to cause thrombocytopenia, (C) Is more likely to elicit an allergic reaction, (D) Stimulates production of a wider variety of hematopoietic stem cells
Answer is D. Stimulates production of a wider variety of hematopoietic stem cells GM-CSF has wider biologic activity than G-CSF; it stimulates early myeloid stem cells in addition to cells destined become neutrophils.