Which of the following disorder of mother leads to microcephaly in baby -: (A) SLE, (B) Hepatitis A, (C) Phenylketonuria, (D) All
Answer is C. Ans. is 'c' i.e., Phenylketonuria Microcephaly o Microcephaly is defined as a head circumference that measures more than three standard detion below the mean for age. Causes of microcephaly Primary (genetic) Secondry (Nongenetic) o Familial (autosomal recessive) o Radiation o Autosomal dominant o Alcohol o Down syndrome o Phenytoin o Edward syndrome o Infection ---> Rubella, CMV, Toxoplasma