Which of the following is NOT a myeloproliferative disease:: (A) Polycythemia rubra vera, (B) Acute myeloid leukemia, (C) Chronic myeloid leukemia, (D) Essential thrombocytosis
Answer is B. Answer is B (Acute myeloid leukemia) The myeloproliferative disorders are characterized pathophysiologically by clonal expression of a multipotent hematopoitic progenitor cell with the overproduction of one or more of the formed elements of Blood. These disorders may transform into acute leukemia naturally or as a consequence of mutagenic treatment. Myeloproliferative disorders classically include: - Polycythemia veraQ - Idiopathic myelofibrosisQ - Essential thrombocytosisQ - Chronic myeloid leukemiaQ