Which one of the following is HLA-associated diabetes mellitus?: (A) Type I diabetes mellitus, (B) Type II diabetes mellitus, (C) Stress related diabetes mellitus, (D) Gestational diabetes mellitus
Answer is A. Type 1 diabetes mellitus is also called HLA associated diabetes. Type 1 diabetes shows genetic susceptibility. Most impoant locus is the HLA gene cluster on chromosome 6p21,which according to some estimates contributes as much as 50% of the genetic susceptibility to diabetes. (Ref:ROBBINS Text book of pathology)