Arrange the steps in apoptosis in sequence of occurrence: 1. Release of cyt c in cytoplasm2. Activation of APAF-13. Removal of BCL-2 4. Caspase activation: (A) 3-1-2-4, (B) 4-2-1-3, (C) 1-2-4-3, (D) 3-2-4-1
Answer is A. Intrinsic Pathway of Apoptosis:- Apoptosis causes fragmentation of DNA, which gives Step-Ladder pattern on DNA gel electrophoresis.