What is the cell of origin of primary lymphoma of the GI tract associated with celiac disease?: (A) B-cell, (B) T-cell, (C) Histiocyte, (D) Dendritic cell
Answer is B. Lymphomas are progressive neoplastic condition of lymphoreticular system arising from stem cells. Lymphomas are the 3rd most common malignancy among children comprising 15% of paediatric cancers. Primary lymphoma of the GI tract associated with Celiac sprue--intestinal T cell lymphoma. Reference : page 253 SRB's manual of surgery 5th edition