In Pemphigus Vulgaris, autoantibodies are formed against which of the following cell adhesion molecule?: (A) Selectin, (B) Cadherin, (C) Integrin, (D) IGSF CAM
Answer is B. In Pemphigus Vulgaris (Intraepithelial), autoantibodies are formed against Desmosomes(Cadherin) whereas, in Bullous pemphigoid(Subepithelial), autoantibodies are formed against Hemidesmosomes.