Which of the following drug does not cause nephrotoxicity?: (A) Cisplatin, (B) Cyclophosphamide, (C) Cyclosporine, (D) Sirolimus
Answer is D. Sirolimus is a non-nephrotoxic -mTOR inhibitor with a long half-life of 62 hours. It was the first mTOR inhibitor to be developed in solid organ transplantation as it inhibits cell proliferation .