The drug which acts by inhibiting oxidative phosphorylation in helminths?: (A) Niclosamide, (B) Piperazine, (C) Praziquantel, (D) Mebendazole
Answer is A. Niclosamide is a chlorinated salicylamide for most cestode infections acts by, inhibiting oxidative phosphorylation. But post drug purging is required for niclosamide, unlike praziquantel and albendazole.Ref: Sharma and Sharma 2nd e/pg 805.