In which of the following types of breast carcinoma, would you consider biopsy of opposite breast: (A) Adenocarcinoma-poorly differentiated, (B) Medullary carcinoma, (C) Lobular carcinoma, (D) Comedo carcinoma
Answer is C. In lobular carcinoma because: High chance to predispose to invasive carcinoma. 35% of lobular carcinoma in situ may devolop invasive lobular carcinoma either in the same or contralateral breast, 65% may devolop invasive ductal carcinoma. It is multifocal, bilateral(50%). So biopsy from opposite breast should be taken. Reference: SRB's Manual of Surgery, 6th Edition, page no = 526.