Adequacy of D-penicillamine treatment in wilson is monitored by measuring the:: (A) 24 hour urinary copper, (B) Serum ceruloplasmin, (C) Disappearance of KF ring, (D) Serum copper level in the fasting state
Answer is A. D-Penicillamine treatment in wilson disease: Adequacy of treatment is monitored by measuring 24-hour urinary copper excretion while on treatment. The most impoant sign of efficacy is a maintained clinical and lab improvement. Serum ceruloplasmin decrease after initiation of treatment. Ref: Journal of Hepatology 2012 vol. 56 / 671-685.