Excess of which of following can result in cataract: (A) Sugar alcohol, (B) Glucose, (C) Sugar amines, (D) Galactose
Answer is A. Sugar Alcohols and cataract: = Reduction of monosaccharides forms sugar alcohols = sugar alcohols are hygroscopic in nature, absorb water, and will cause cell swelling = They especially get accumulated in the lens of the eye causing cataract. Examples: Glucose forms sorbitol in diabetes and leads to snowflake cataract In galactosemia, Excess Galactose is reduced to galactitol and give rise to oil drop cataract