Guthrie test can be used for the diagnosis of:: (A) Tyrosinemia, (B) Galactosemia, (C) Alkaptonuria, (D) Phenylketonuria
Answer is D. The bacterial inhibition assay of Guthrie is used for Phenylketonuria. Tyrosinemia- | serum AFP & succinyl acetone in serum & urine Galactosemia- urine: positive Benedict test Alkaptonuria- Gas chromatography & mass spectrometry (GCMS)