Which glycogen storage disease (GSD) does not affect muscles?: (A) Type I, (B) Type II, (C) Type III, (D) Type V
Answer is A. Type I GSD (Von Gierke disease) is a liver glycogenoses i.e. involves liver Type 2 (Pompe disease), type V (McArdles disease) and type VII ( Tarui disease) involves muscles (Muscle Glycogenoses) Type 3 GSD (Cori's disease) is predominantly a liver glycogenoses but skeletal muscle involvement may also be seen.