Which of the following does not dependent on insulin GLUT4 for glucose uptake?: (A) Brain, (B) Skeletal muscles, (C) Cardiac muscle, (D) Adipose tissue
Answer is A. Tissue-like brain is still able to impo glucose from the serum through maintaining a basal level glucose receptors on the cell surface.The general picture is as follows :Glucose is hydrophilic and cannot cross cell membrane most cell have membrane proteins that can shuttle glucose from one side to otherRef: DM Vasudevan, 7th edition, page no: 318