Cytokines-: (A) Includes interleukins, (B) Produce only in sepsis, (C) Are polypeptide (complex protein), (D) Highly specific action
Answer is A. Robbins basic pathology 9th edition page no 48 Molecularly characterized cytokines are called interleukins. The four-a-helix bundle family: member cytokines have three-dimensional structures with four bundles of a-helices. This family, in turn, is divided into three sub-families: the IL-2 subfamily the interferon (IFN) subfamily the IL-10 subfamily. The first of these three, the IL-2 subfamily, is the largest. It contains several non-immunological cytokines including erythropoietin (EPO) and thrombopoietin(TPO). Fuhermore, four-a-helix bundle cytokines can be grouped into long-chain and sho-chain cytokines