Alkalinization of urine is done during administration of which of the folloiwng chemotherapeutic drugs?: (A) Ara-C, (B) Methotrexate, (C) Cisplatin, (D) Ifosafamide
Answer is B. Ans is 'b' i.e. Methotrexate o Urine alkalinization by NaHCO3 enhances the elimination of weak acids, e.g. Salicylates, Phenobarbitone, Chlorpropamide, formic acid and methotrexate.