The characteristic lesion of atherosclerosis is: (A) Fibrinoid necrosis of the media, (B) Giant cell reaction in the retina and internal elastic lamina, (C) Organised thrombus in the affected segment, (D) 'Fibro-fatty' lesion in the intima of the blood vessels
Answer is D. Atherosclerosis is a intima based lesion composed of a fibrous cap and an atheromatous core: the constituents of the plaque include smooth muscle cells, ECMs, inflammatory cells, lipids and necrotic debris Robbins 9th edition page no 343