Deficiency of purine nucleoside phosphorylase causes: (A) Complement deficiency, (B) Cellular immunodeficeincy, (C) Humoral immunodeficeincy, (D) Combined immunodeficeincy
Answer is B. A combined T cell and B cell immunodeficiency that is a rare autosomal recessive metabolic disorder that has material basis in mutation in the PNP gene and characterized mainly by decreased T-cell function. Ref-Sathyanarayana 4/e