The Electron Microscopy is viually diagnostic in renal biopsy study of:: (A) Goodpasture's syndrome, (B) Churg-Strauss syndrome, (C) Alpo syndrome, (D) Wegner's granulomatosis
Answer is C. For Alpo syndrome, the most diagnostic morphologic lesion is seen only by electron microscopy as an irregularly thickened GBM, with splitting of the lamina densa into interlacing lamellae that surround electron-lucent areas.