In diseases of growth hormone cell death occurs by-: (A) Aging, (B) Apoptosis, (C) Necrosis, (D) All of the above
Answer is B. Ans. is 'b' i.e., Apoptosis o GH and IGF-1 (somatomedin) inhibit cell death by apoptosiso Thus, GH deficiency will cause accelerated apoptosis."GH indirectly mediates growth and protein synthesis by triggering the liver and other tissues to produce a group of proteins called insulin-like growth factors (IGFs). These proteins enahnce cellular proliferation and inhibit apoptosis or programmed cell death " -- Science in medicine.