A patient Rajnish having depressive disorder has taken 25 times the normal dose of amitriptyline. Which of the following is not likely to be observed in this patient?: (A) Coma and shock, (B) Hot dry skin, (C) Hypotension, (D) Pinpoint pupil
Answer is D. (Ref: KDT 6/e p444) Amitriptyline is a TCA like imipramine. It causes mydriasis due to anticholinergic activity. Other adverse effects are also similiar to imipramine.