Mrs Reeta Wardhan, a 50 year old female with rheumatoid ahritis is being considered for infliximab therapy. Which of the following test should be performed before beginning treatment: (A) Liver function test, (B) PPD skin test, (C) Pulmonary function test, (D) Visual examination
Answer is B. Ref-Katzung 11/e p633 Infliximab is a monoclonal antibody against TNF-0. It is commonly used to treat moderate to severe rheumatoid ahritis paicularly in patients .adverse effects, including reactivation of latent tuberculosis. All patients being considered for TNF-a inhibitor therapy should have a baseline PPD skin test to screen for latent tuberculosis..