All of the following statements about Hepatitis B arc true, Except: (A) Veical Transmission is more common than horizontal transmission in non-endemic areas, (B) Age of onset determines prognosis, (C) Period of communicability lasts several months, (D) Virus can be detected in blood one month before jaundice
Answer is A. Answer is A (Veical Transmission is more common than horizontal transmission in non-endemic areas) Veical transmission is more common that horizontal transmission in endemic Areas (not in non-endemic areas) Age of onset determines prognosis 'The outcome of HBV infection is age dependent. The development of chronic hepatitis B is inversely related to age and occurs in approximately 95% of persons infected perinatally, in 80% of persons infected in early childhood and in 510% infected after 5 years of age' - Park 20th /188 Period of communicability lasts several months 'The period of communicability is usually several months. The virus is present in the blood during the incubation period (for a month before jaundice) and acute phase of disease' - Park 201h/187 Virus can be detected in blood one month before jaundice 'Circulating HBsAg precedes elevation of aminotransferases and clinical symptoms (jaundice) by 2-6 weeks and remains detectable during the entire icteric or symptomatic phase of acute 'Hepatitis B' and beyond' - Harrison 's 17th /1933 Veical transmission is more common in Endemic areas 'Perinatal transmission (veical) is uncommon in Noh America and Europe (Non-Endemic areas) hut occurs with great frequency and is the most common mode of HBV perpetuation in the Far East and developing countries (Endemic areas)' - Harrison 's 17th/1940,1947