Deficiency of the ' Intrinsic factor of Castle ' causes-: (A) Megaloblastic anemia, (B) Pernicious anemia, (C) Cooley's anemia, (D) Aplastic anemia
Answer is B. Pernicious anemia is a chronic disease resulting from deficiency of Intrinsic factor leading to impaired absorption of Vitamin B12. Megaloblastic anemia is due to deficiency of Cobalamin/folate. Reference: Atlas and text of Hematology, 3rd edition, pg:102. Exam preparatory manual for UGs by Ramdas Nayak page no: 259