Enzyme involved in Variegate porphyria: (A) Ferrochelatase, (B) Protoporphyrinogen oxidase, (C) Uroporphyrinogen decarboxylase, (D) ALA dehydratase
Answer is B. Enzyme InvolvedType Major Signs and SymptomsResults of Laboratory TestsProtoporphyrinogen oxidaseVariegate porphyria (hepatic)Photosensitivity, abdominal pain,neuropsychiatric symptomsUrinary ALA, PBG, and coproporphyrinIII and fecal protoporphyrinIX increasedRef: Harper&;s Biochemistry; 30th edition; Chapter 31 Porphyrins & Bile Pigments