Which of the following hormones is mainly responsible for skeletal maturation?: (A) Testosterone, (B) Estrogen, (C) Growth hormone, (D) Insulin
Answer is A. Testosterone is a major factor responsible for the greater muscle mass and skeletal maturation. It has a myotrophic as well as androgenic (masculinization) action. Growth hormone increases skeletal and visceral growth. Insulin and thyroid hormones provide an additional stimulus for chondrocyte activity and growth of skeleton.