Premature ovarian insufficiency is defined as hypogonadotropic hypogonadism and amenorrhea arising before the age of: (A) 40 years, (B) 45 years, (C) 50 years, (D) 55 years
Answer is A. Premature ovarian failure (POF), traditionally defined as hypogonadotropic hypogonadism and amenorrhea arising before the age of 40.Reference: Clinical gynecologic endocrinology; 10th edition; Chapter 9; Normal and Abnormal Sexual Development; Page no: 463