First change of improvement, noted after iron therapy is initiated: (A) Decreased irritability, (B) Reticulocytosis, (C) Increase in serum iron levels, (D) Replenishment of iron stores
Answer is A. 12-24 hr Replacement of intracellular iron enzymes; subjective improvement; decreased irritability; increased Appetite 36-48 hr Initial bone marrow response; erythroid hyperplasia 48-72 hr Reticulocytosis, peaking at 5-7 days 4-30 days Increase in hemoglobin level 1-3 mo Repletion of stores