A 55-year-old male, with uncontrolled diabetes mellitus and hypeension, developed severe air-borne contact dermatitis. The most appropriate drug for his treatment would be:: (A) Systemic coicosteroids, (B) Thalidomide, (C) Azathioprine, (D) Cyclosporine
Answer is C. C i.e. Azathioprine In contact dermatitis, the allergic reaction is mediated by delayed hypersensitivity (cell mediated immunity). It is treated by: - Antihistamincis - Steroids (topical/systemic) - Agents depressing cell mediated immunity as cyclosporine, tacrolimus, azathioprine