Acquired multistep drug resistance can be seen in all except:: (A) Erythromycin, (B) Streptomycin, (C) Tetracycline, (D) Chloramphenicol
Answer is B. Development of acquired resistance may be due to single-step mutation (as seen with streptomycin  and rifampicin) or multi-step mutation (erythromycin, tetracycline and chloramphenicol).