Which of the following is not a channelopathy?-: (A) Cystic fibrosis, (B) Liddle's syndrome, (C) Tay-sachs disease, (D) Hypokalemic periodic paralysis
Answer is C. Channelopathies are diseases caused by the disturbed function of ion channel subunits or the proteins that regulate them. Tay-Sachs disease is a GM2 gangliosidosis caused by the deficiency of enzyme hexosaminidase, subunit.