Ramesh 40 yrs make patient presenting with polyuria,pain abdomen,nausea,vomitings,altered sensorium was found to have bronchiogenic carcinoma.the electrolyte abnormality seen in him would be: (A) Hypokalemia, (B) Hyperkalemia, (C) Hypocalcaemia, (D) Hypercalcaemia
Answer is D. Presence of polyuria, abdominal pain and general Symptoms such as nausea, vomiting,and altered sensorium in a patuent with bronchiogenic carcinoma suggest a diagnosis of hypercalcaemia secondary to paraneoplastic syndrome from PTH related peptide production. Ref Harrison 19th edition pg 313