In cystic fibrosis mutation occurs at?: (A) One gene, (B) Two gene, (C) Three gene, (D) Four gene
Answer is A. Ans. (a) One gene(Ref: Robbins 9th/pg 466-470)Cystic Fibrosisis an Autosomal recessive disease, caused by mutation in Cystic Fibrosis Transmembrane conductance Regulator (CFTR) gene on chr7q31.2, which leads to abnormal function of ion transport channel.