Drug used for Buerger's disease ?: (A) Xanthinol nicotinate, (B) Propranolol, (C) GTN, (D) All the above
Answer is A. . Drug used in Buerger's disease is Xanthinol nicotinate. Complamina retard (xanthine nicotinate) tablet was used daily once earlier. Now , graded injection of xanthine nicotinate 3000 mg from day 1 to 9000 mg on day 5 is used to promote ulcer healing . It also helps to increase claudication distance as a temporary basis. Beta blockers such as propranolol & GTN have no ulcer healing propey in case of Thromboangitis obliterans (Buerger's disease). Ref :- SRB manual of Surgery 4th edition , Pg 184