Syndrome associated with anosmia is:: (A) Goldenhar syndrome, (B) Kallmann syndrome, (C) Prader Willi syndrome, (D) All of the above
Answer is B. The most well-known type of congenital anosmia is Kallmann syndrome, an X-linked disorder. Caused by mutation in the KAL gene, Kallmann syndrome is characterized by hypogonadotropic hypogonadism, which results when olfactory receptor neurons and neurons synthesizing gonadotropin-releasing hormone fail to migrate from the olfactory placode.