A patient of thrombosis if veins has been receiving coumarin therapy for three years. Recently she developed bleeding tendency .how will you reverse the effect of coumarin therapy: (A) Protamine injection, (B) Vitamin K injection, (C) Infusion of fibrinogen, (D) Whole blood transfusion
Answer is B. Refer KDT 6/e p602 Vitamin k is used to reverse bleeding tendancy in warfarin overdose whereas fresh frozen plasma is treatment of choice for bleeding due to warfarin