Tolvaptan is used for:-: (A) SIADH, (B) Central DI, (C) Von Wilebrand disease, (D) Catecholamine resistant Shock
Answer is A. In SIADH, ADH increases so more activation of V2 receptor, so more water absorption. The patients suffer from dilutional hyponatremia. Option B: Managed by Desmopressin / Nasal spray Option C: Managed by Cryoprecipitate / VW Factor Option D: No definitive treatment, patient dies more often