Conversion of Pyruvate to Acetyl CoA does not require: (A) Thiamine, (B) TPP, (C) Pyridoxine, (D) FAD
Answer is C. Pyruvate is conveed to acetyl CoA by oxidative decarboxylation catalysed by a multienzyme complex, known as pyruvate dehydrogenase complex (PDH) The enzyme PDH requires five cofactors (coenzymes), namely--TPP(thiamine pyrophosphate), lipoamide, FAD, coenzyme A and NAD+ ref Satyanarayana biochemistry 4th ed page 252