In which of the following c-ANCA is seen?: (A) Wegener's granulomatosis, (B) Polyarteritis nodosa, (C) Churg-Strauss syndrome, (D) Bechet's syndrome
Answer is A. a. Wegener's granulomatosis(Ref: Nelson's 20/e p 1176-1180, Ghai 8/e p 628)C-ANCAP-ANCA (against Myeloperoxidase)Wegener's GranulomatosisQ (90-95%)* Microscopic PAN (microscopic polyangitis)* Churg-Strauss syndromeQ* Drugs (hydralazine, propythiouracil)* Crescentic GlomerulonephritisQ* Goodpasteur's syndromeQ* Ulcerative colitis* Primary sclerosing cholangitisQ