Ideally children with thalassemia should be transfused with:: (A) Packed RBC, (B) Platelet rich plasma, (C) Saline washed packed RBC, (D) Whole blood
Answer is C. - Saline washed RBCs are specially indicated in conditions requiring repeated transfusion when the chances of uicarial reactions due to plasma is high. - These have negligible plasma proteins and just 10% leucocytes. - It is preferred in the management of babies suffering from thalassemia and paroxysmal nocturnal hemoglobinuria.