Concerning streptogramins, which one of the following statements is FALSE?: (A) They are active against methicillin-resistant staphylococci, (B) They may cause a syndrome of ahralgia and myalgia, (C) They induce formation of hepatic drug metabolizing enzymes, (D) They are used in the management of infections caused by vancomycin-resistant enterococci
Answer is C. (Ref: Katzung 10/e p753) Streptogramins like quinpristin and dalfopristin possess microsomal enzyme inhibitory propey (NOT inducing). These are effective against MRSA and VRE infections.