Best method to diagnose typhoid in the first week is ?: (A) Blood cultrue, (B) Bone marrow cultrue, (C) Urine culture, (D) Stool culture
Answer is B. Blood, intestinal secretions (vomitus or duodenal aspirate), and stool culture results are positive for S typhi in approximately 85%-90% of patients with typhoid fever who present within the first week of onset. They decline to 20%-30% later in the disease course Ref Harrison20th edition pg 1079