A reactant generated by neutrophils that plays an impoant role in bacterial killing is: (A) NADPH oxidase, (B) Hexose monophosphate shunt, (C) G proteins, (D) Superoxide anion
Answer is D. Superoxide anion is generated when oxygen is reduced by cytoplasmic NADPH. The reduction is carried out by the enzyme NADPH oxidase, which is not a reactant but a catalyst activated in cells responding to bacteria.