Which of the following is a ourable prognostic factor in a case of neuroblastoma?: (A) Diploidy, (B) N-myc amplification, (C) Chromosome / p depletion, (D) Trk A expression
Answer is D. High level expression of Trk A gene is associated with a ourable outcome in neuroblastoma. Favorable prognostic factors in neuroblastoma are: Age less than 1 year, Stage I and II, hyperdiploid or near diploid tumors. Ref: Robbins Pathologic Basis of Disease, 6th Edition, Page 485, 487