Sirolimus is more likely to cause ____________ more than cyclosporine:: (A) Hypeension, (B) Osteoporosis, (C) Renal insufficiency, (D) Thrombocytopenia
Answer is D. * Sirolimus (rapamycin) results in suppression of bone marrow,mainly causing thrombocytopenia.other adverse effects are diarrhoea,liver damage and pneumonitis. * Cyclosporine and tacrolimus cause nephrotoxicity,hepatotoxicity,neurotoxicity as an adverse effect.