Extended activity of ii-lactamases inactivate ?: (A) Cephalosporins-III generation, (B) Macrolides, (C) Quinolone, (D) Aminoglycosides
Answer is A. Ans. is 'a' i.e., Cephalosporins-III generation ESBL are lactamases that mediate resistance (by hydrolyzing) to extended spectrum (third generation) cephalosporins, penicillins and monobactams (e.g. aztreonam).