Which one of the following medications is most likely to be responsible for this appearance?: (A) Clarithromycin, (B) Dexamethasone, (C) Doxorubicin, (D) Efavirenz
Answer is C. Answer C. DoxorubicinSeveral chemotherapeutic drugs (including doxorubin and cyclophosphamide) cause dyspigmentation. Other groups of drugs that cause this problem include antimalarials, amiodarone, heavy metals (but not iron), tetracyclines, and antipsychotics.