Oxaloacetate + Acetyl CoA → Citrate + CoASH. This reaction is: (A) Reversible, (B) Irreversible, (C) Can be reversed by catalase, (D) Competitive
Answer is B. There are two irreversible steps : (i) Oxaloacetate to citrate, catalyzed by citrate synthase, and (ii) α - ketoglutarate to succinyl CoA, catalyzed by α - ketoglutarate dehydrogenase.