Which of the following mechanism is associated with a covalent modification: (A) Reversible phosphorylation, (B) Acetylation, (C) ADP-ribosylation, (D) All the above
Answer is D. Acetylation, ADP-ribosylation, methylation, and phosphorylation are all examples of "reversible" covalent modifications.This is very impoant pa of enzymatic regulation (EX: Phosphorylation-Dephosphorylation reactions) Harper 30th edition pg: 92