Chest wall rigidity can be caused by rapid infusion of which of the following opioid-: (A) Fentanyl, (B) Sufentanyl, (C) Remifentanil, (D) All of the above
Answer is D. Rapid administration of larger doses of opioids (paicularly fentanyl, sufantanyl, Remifentanil and alfentanyl) can induce chest wall rigidity severe enough to prevent adequate bag and mask ventilation. This is centrally mediated muscle contention is effectively treated with neuromuscular blockers.