Inhalational anesthetic with highest respiratory irritation is: (A) Sevoflurane, (B) Halothane, (C) Nitrous Oxide, (D) Desflurane
Answer is D. * Desflurane, a fluorinated inhalational anesthetic agent - is highly irritant on the tracheobronchial tree - making it unsuitable for use as the primary anesthetic for induction of anesthesia. * Among the fluorinated inhalational anaesthetics, Desflurane and Isoflurane are respiratory irritants; Sevoflurane is devoid of tracheobronchial irritation.Ref:- Goodman & Gilman Pharmacological Basis of Therapeutics 13th Ed; Pg num:- 395