Best method for HbA1c estimation is?: (A) Affinity chromatography, (B) Ion exchange chromatography, (C) Electrophoresis, (D) HPLC
Answer is D. Ans. (d) HPLCFour basic types of methods are used most commonly to measure HbA1c: immunoassay, ion-exchange high- performance liquid chromatography (HPLC), boronate affinity HPLC, and enzymatic assays. The gold standard is HPLC method