The most impoant buffer in interstitial fluid:: (A) Phosphate, (B) Bicarbonate, (C) Histidine, (D) Protein
Answer is B. The chemical buffer systems in the body - bicarbonate system, phosphate system, and the proteins. Bicarbonate buffer is quantitatively the most impoant buffer in ECF compament; it buffers non-carbonic acid. Hence, option B is correct. Intracellular proteins account for >70% of I/C buffering . Phosphate helps in intracellular buffering .