Activity of factor VIII procoagulant is deficient in:: (A) Haemophilia, (B) Von Willibrand's disease, (C) ITP, (D) Sickle cell anemia
Answer is A. A i.e. HemophiliaHemophilia A is a disorder of coagulation occurs due to deficiency or reduced activity of factor VIII.FeaturesHemophilia A (Classical hemophilia)Hemophilia B (Christmas disease)DefectDeficiency of coagulant subunit of factor VIII i.e. VIIICfactor VIII=VIIIC + VWFDeficiency of factor IXQPathway ofcoagulation affectedInstrinsic pathwayIntrinsic pathway