coordinates = [[42.3581, -71.0636], [42.82995815, -74.78991444], [
    43.17929819, -78.56603306], [43.40320216, -82.37774519], [43.49975489, 
    -86.20965845], [41.4338549, -108.74485069], [40.67471747, -112.29609954
    ], [39.8093434, -115.76190821], [38.84352776, -119.13665678], [37.7833,
    -122.4167]]
m = folium.Map(location=[41.9, -97.3], zoom_start=4)
my_PolyLine = folium.PolyLine(locations=coordinates, weight=5)
m.add_children(my_PolyLine)
Распечатайте линию/многолинию в новом слое поверх карты с помощью Folium