import pygame, time, datetime, ctypes
from pygame.locals import *
from ctypes import windll
pygame.init()
set_window_pos = windll.user32.SetWindowPos
monitorsize = ctypes.windll.user32
resolution_X = monitorsize.GetSystemMetrics(0)
resolution_Y = monitorsize.GetSystemMetrics(1)
screen = pygame.display.set_mode((255, 242), pygame.NOFRAME)
set_window_pos(pygame.display.get_wm_info()['window'], -1, resolution_X - 
    255, 50, 0, 0, 1)
Fullscreen Python TKinter or wxPython window, but 'stay at the bottom' of all windows?