from subprocess import Popen, PIPE
scpt = """
    on run {x, y}
        return x + y
    end run"""
args = ['2', '2']
p = Popen(['osascript', '-'] + args, stdin=PIPE, stdout=PIPE, stderr=PIPE)
stdout, stderr = p.communicate(scpt)
print((p.returncode, stdout, stderr))
Как встроить AppleScript в скрипт Python?