surf = cairo.ImageSurface(cairo.FORMAT_ARGB32, 8, 8)
ctx = cairo.Context(surf)
layout = PangoCairo.create_layout(ctx)
pctx = layout.get_context()
fo = cairo.FontOptions()
fo.set_antialias(cairo.ANTIALIAS_SUBPIXEL)
PangoCairo.context_set_font_options(pctx, fo)
Using PangoCairo with PyGObject API