text = """time,volume,complete,closeBid,closeAsk,openBid,openAsk,highBid,highAsk,lowBid,lowAsk,closeMid
2016-08-07 21:00:00+00:00,9,True,0.84734,0.84842,0.84706,0.84814,0.84734,0.84842,0.84706,0.84814,0.84788
2016-08-07 21:05:00+00:00,10,True,0.84735,0.84841,0.84752,0.84832,0.84752,0.84846,0.84712,0.8482,0.84788
2016-08-07 21:10:00+00:00,10,True,0.84742,0.84817,0.84739,0.84828,0.84757,0.84831,0.84735,0.84817,0.847795
2016-08-07 21:15:00+00:00,18,True,0.84732,0.84811,0.84737,0.84813,0.84737,0.84813,0.84721,0.8479,0.847715
2016-08-07 21:20:00+00:00,4,True,0.84755,0.84822,0.84739,0.84812,0.84755,0.84822,0.84739,0.84812,0.847885
2016-08-07 21:25:00+00:00,4,True,0.84769,0.84843,0.84758,0.84827,0.84769,0.84843,0.84758,0.84827,0.84806
2016-08-07 21:30:00+00:00,5,True,0.84764,0.84851,0.84768,0.84852,0.8478,0.84857,0.84764,0.84851,0.848075
2016-08-07 21:35:00+00:00,4,True,0.84755,0.84825,0.84762,0.84844,0.84765,0.84844,0.84755,0.84824,0.8479
2016-08-07 21:40:00+00:00,1,True,0.84759,0.84812,0.84759,0.84812,0.84759,0.84812,0.84759,0.84812,0.847855
2016-08-07 21:45:00+00:00,3,True,0.84727,0.84817,0.84743,0.8482,0.84743,0.84822,0.84727,0.84817,0.84772
"""
df = pd.read_csv(StringIO(text), parse_dates=[0])
Проблемы с производительностью с пандами и фильтрацией по столбцу даты и времени