my_worksheet.password = 'something_difficult_to_guess'
editable = easyxf('protection: cell_locked false;')
read_only = easyxf('')
my_worksheet.write(0, 0, "Can't touch this!", read_only)
my_worksheet.write(2, 2, 'Erase me :)', editable)
Python xlwt - making a column readonly (cell protect)