import xmlrpc.client
from django.db.models.signals import post_save
from app.models import MyModel

def ping_handler(sender, instance=None, **kwargs):
    if instance is None:
        return
rpc = xmlrpc.client.Server('http://ping.feedburner.google.com/')
rpc.weblogUpdates.ping(instance.title, instance.get_absolute_url())
post_save.connect(ping_handler, sender=MyModel)
Ping FeedBurner in Django App