This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
The effect of progesterone on lipids 
Select and explain. 
A. Lowers LDL, increases HDL, B. Lowers LDL and HDL, C. Lowers HDL and increases LDL, D. Increases LDL and HDL
C: Lowers HDL and increases LDL
Answer: C: Lowers HDL and increases LDL 
Explanation: While part of the administered progestogen is metabolized to oestrogen, it is also partly metabolized to testosterone. If administered to a patient during pregnancy, some progestogens have virilizing effect upon a female fetus. Lipid metabolism decreases HDL but increases low-density lipoprotein. Thus, it is harmful to the heart.
It improves the immune response