This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
A 45 yrs old man presents with progressive cervical lymph nodes enlargement, since 3 months; most diagnostic investigation is: 
Select and explain. 
A. X-ray soft tissue, B. FNAC, C. Lymph node biopsy, D. None of the above
C: Lymph node biopsy
Answer: C: Lymph node biopsy 
Explanation: In cervical lymph node enlargement, if no mucosal lesion is detected, an excision biopsy of the largest node should be performed. Ref: Harrison's Internal Medicine, 15th Edition, Page 362 and 18th Edition, Page 467.