This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Which of the following anti-histaminie has very less cholinergic side effects? 
Select and explain. 
A. Promethazine, B. Chlorpheniramine, C. Hydroxyzine, D. Loratidine
D: Loratidine
Answer: D: Loratidine 
Explanation: Loratidine is a second generation anti-histamine which has lesser sedation and cholinergic side effects.