This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Most specific immunohistochemical marker for melanoma cells is 
Select and explain. 
A. S-100, B. Melan-A, C. HMB-45, D. Chromogranin
C: HMB-45
Answer: C: HMB-45 
Explanation: HMB-45 is the most specific for melanoma cells.
S-100 is the most sensitive marker.