This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Respiratory system, Subject name: Pharmacology
All of the following drugs can precipitate acute attack of asthma except 
Select and explain. 
A. Phenyl butazone, B. Naproxen, C. Glucocoicoids, D. Aspirin
C: Glucocoicoids
Answer: C: Glucocoicoids 
Explanation: Refer KDT 6/e p217 COX inhibitors like aspirin, indomethacin, naproxen, and phenyl butazone etc inhibit the formulation of PGs from arachidonic acid This results in diversion of metabolism of arachidonic acid to produce LTs Large excess of LTs are therefore produced with the use of NSAIDS These drugs therefore Cam result in precipitation of acute attack of asthma