This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General Pharmacology, Subject name: Pharmacology
In metabolism, all of the following reactions occur in phase one except? 
Select and explain. 
A. Oxidation, B. Reduction, C. Conjugation, D. Deamination
C: Conjugation
Answer: C: Conjugation 
Explanation: Ans. C. ConjugationPhase-1 (Non-synthetic): (oxidation/reduction/hydroiysis/ cyclization/ Decyclization)a. Convert lipophilic compounds to more polar compounds, by introducing or unmasking a functional group such as OH,-NH2 .b. OXIDATION is the most common pathway in Phase-1 reactionc. Microsomal drug oxidations require CYP450, P450 reductase, NADPHQ & oxygend. REMEMBER oxidation includes dealkylation, deamination and hydroxylation