This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: ENT
Reinke edema is associated with: 
Select and explain. 
A. Alcoholism, B. Smoking, C. Malnutrition, D. None of the above
B: Smoking
Answer: B: Smoking 
Explanation: Reinke Edema has the following features. Strong association with cigarette smoking and heavy voice use. Diffuse edematous changes of the vocal cords. Usually bilateral.