This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology and breast, Subject name: Surgery
The treatment of choice for Anaplastic carcinoma of thyroid infiltrating trachea and sternum will be 
Select and explain. 
A. Radical excision, B. Chemotherapy, C. Radiotherapy, D. Palliative treatment
D: Palliative treatment
Answer: D: Palliative treatment 
Explanation: Anaplastic carcinoma of thyroid with distant metastasis or invasion into locally unresectable structures, such as the trachea or vasculatureof the anterior mediastinum, leads to a more conservative surgical approach, such as tracheostomy (palliation) as prognosis is very poor Postoperative external beam irradiation or adjunctive chemotherapy adds little to the overall prognosis but can be considered. note : question is treatment of choice, treatment of choice here is palliative care. Source : Sabiston 20th edition pg: 910