This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
An Afroamerican boy of 6 years of age presented with abdominal pain, chronic hemolysis and abnormal RBC shape on peripheral smear. Most likely disorder responsible for this condition is - 
Select and explain. 
A. Trinucleotide repeat, B. Point mutation, C. Antibodies against RBC membrane, D. Genetic imprinting
B: Point mutation
Answer: B: Point mutation 
Explanation: . Point mutation