This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General anatomy, Subject name: Anatomy
Which of the following is not true regarding IgE antibodies 
Select and explain. 
A. It mediated release of histamine and other chemicals mediator, B. It is the primary antibody involved in allergic reaction, C. It is involved in anti parasitic immune response, D. May cross the placenta and fix complement
D: May cross the placenta and fix complement
Answer: D: May cross the placenta and fix complement 
Explanation: May cross the placenta and fix the compliment _IgG not IgE IgE's main function is immunity to parasites such as helminths like Schistosoma mansoni, Trichinella spiralis, and Fasciola hepatica. IgEis utilized during immune defense against ceain protozoan parasites such as Plasmodium falciparum