This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Ophthalmology
Enucleation of the eyeball is contraindicated in - 
Select and explain. 
A. Endophthalmitis, B. Panophthalmitis, C. Intraocular tumours, D. Painful blind eye
B: Panophthalmitis
Answer: B: Panophthalmitis 
Explanation: Enucleation of eye ball is contraindicated in panophthalmitis, because if optic nerve sheath is touched, the infection may spread intracranially.