This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: New Born Infants, Subject name: Pediatrics
A new bom presented with Jaundice. Most diagnostic investigation of choice is 
Select and explain. 
A. Total and Direct bilirubin, B. Conjugated bilirubin, C. Serum. Bilirubin, D. Uroporphyrin levels
A: Total and Direct bilirubin
Answer: A: Total and Direct bilirubin 
Explanation: (Total and Direct bilirubin) (171 - Ghair 6th)* Unconjugated Hyperbilirubinemia1. Clinical Jaundice appearing in the first 24 hours2. Increase in level of total bilirubin by more than 0.5 mg/dL /hour or 5mg/dL /24 hours3. Total bilirubin >15mg/dL (hyper bilirubinemia)4. Direct bilirubin >2.0mg /dL* Conjugated hyperbilirubinemia - is rare in newborn, conjugated hyper bilirubinemia is defined as a direct reacting fraction of >2mg/dL or >15% of the total bilirubin