This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology and breast, Subject name: Surgery
Treatment of Hormone dependent fungating carcinoma of breast with secondaries in the lung in a female patient aged 30 years is 
Select and explain. 
A. Simple mastectomy followed by oophorectomy, B. Radical mastectomy followed by oophorectomy, C. Adrenalectomy, D. Lumpectomy followed by castration
A: Simple mastectomy followed by oophorectomy
Answer: A: Simple mastectomy followed by oophorectomy 
Explanation: Hormonal therapy in Carcinoma Breast Ovarian suppression or ablation Bilateral oophorectomy. Medically by LHRH agonist (Goserelin, leuprolide) SERM: Tamoxifen and Raloxifen Aromatase Inhibitors Non-steroidal : Letrozole & Anastrazole Steroidal : Exmestane Anti-Estrogens Fulvestrant Progestins Megesterol & Medroxyprogesterone acetate Ref: schwaz's principle of surgery 10th edition Pgno : 552-553