This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy: General Principles, Subject name: Pharmacology
All of the following anticancer drugs act on G2 phase except: 
Select and explain. 
A. Paclitaxel, B. Etoposide, C. Irinotecan, D. Bleomycin
A: Paclitaxel
Answer: A: Paclitaxel 
Explanation: Ans. (A) Paclitaxel(Ref: Katzung 13th/e p921)Paclitaxel is a taxane that act on mitotic spindle. Drugs acting on mitotic spindle act on M phase of cell cycle.Phase of cell cycleDrugs actingG1EtoposideSAntimetabolitesG2BleomycinEtoposideIrinoctecanTopotecanMVinca alkaloidsTaxanes