This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pathology
ANCA positive vasculitis is 
Select and explain. 
A. Churg-strauss syndrome, B. Polyaeritis nodosa, C. Wegener granulomatosis, D. 1 & 3
D: 1 & 3
Answer: D: 1 & 3 
Explanation: Wegener granulomatosis is likely to be initiated as a cell mediated hypersensitivity response directed aganist inhaled infectious or environmental antigens. PR3-ANCA are present in almost 95 c/o of cases Chrug - stauss syndrome is a small vessel necrotising vasculitis classically associated with asthma, allergic rhinitis, lung infiltrate, etc. This syndrome may stem from hyperresponsiveness to normally innocuous allergic stimuli. MPO-ANCA s are present in a minority of cases Robbins 9 th edition page no. 354