This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Refractory schizophrenia - What is the treatment of choice - 
Select and explain. 
A. Haloperidol, B. Flupenthixol, C. Trifluoperazine, D. Clozapine
D: Clozapine
Answer: D: Clozapine 
Explanation: Ans. is 'd' i.e., Clozapine o Clozapine (but not the newer atypicals) is more effective than classical agents for resistant schizophrenia.