This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Urology, Subject name: Surgery
Post Kidney transplantation complication caused by CMV is? 
Select and explain. 
A. Parotitis, B. Cholecystitis, C. Pyelonephritis, D. GI Necrosis and stricture
C: Pyelonephritis
Answer: C: Pyelonephritis 
Explanation: The answer here is simple as the pyelonephritis is the only option related to kidney. The impoant point to revise here is that CMV in transplant patients is the a complication of immunosuppression SIDE EFFECTS OF NON SPECIFIC IMMUNOSUPPRESSION 1) INFECTION : bacterial and fungal infections are most common , risk greatest in first 6 months , chemoprohylaxis and vaccinations for high risk patients , viral infections are from reactivation of latent virus or a primary infection . CMV is a major problem . 2) MALIGNANCY : children are at high risk for lymphoproliferative disorders , sq cell ca very common ref ( Bailey 27th ed , chapter 82 , pg 1541