This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Which of the following hepatitis viruses have significant perinatal transmission? 
Select and explain. 
A. Hepatitis A virus, B. Hepatitis B virus, C. Hepatitis C virus, D. Hepatitis E virus
B: Hepatitis B virus
Answer: B: Hepatitis B virus 
Explanation: The hepatitis virus with significant perinatal transmission is Hepatitis - B virus. Hepatitis - C virus may also be transmitted if there are high levels of viremia. Hepatitis B is a DNA virus, it is acquired perinatally from a carrier mother, or later in life from exposure to contaminated blood through shared needles, needle sticks, skin piercing, tattoos or sexual transmission. Infants are infected with hepatitis B at the time of bih. Intrauterine transmission of this virus occur rarely. Ref: Harrisons Internal Medicine, 18th Edition, Chapter 304 ; CURRENT Diagnosis and Treatment: Pediatrics, 20th Edition, Chapter 1