This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolic disorders - 1, Subject name: Orthopaedics
Which bisphosphonate is approved for the treatment of osteoporosis and is given on yearly basis? 
Select and explain. 
A. Alendronate, B. Zoledronate, C. Risedronate, D. Ibandronate
B: Zoledronate
Answer: B: Zoledronate 
Explanation: Zoledronate- approved for the treatment of osteoporosis and is given on yearly basis Ibandronate- given on monthly basis