This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Which of the following cephalosporins does not need dose modifications even in presence of decreased GFR- 
Select and explain. 
A. Cefipine, B. Cefoperazone, C. Cefotaxim, D. Cefuroxine
B: Cefoperazone
Answer: B: Cefoperazone 
Explanation: Ans. is 'b' i.e., Cefoperazone o Cefoperazone is primarily exreted in bile in contrast to other cephalosporins that are usually excreted by the kidney --> safe in renal failure. o Cephalosporins that can be used in presence of renal failure :- i) Cefoperozone, ii) Ceftriaxone, iii) Cefoperamide