This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Inflammatory Bowel Disease, Subject name: Medicine
DOC of acute exacerbation of ulcerative colitis? 
Select and explain. 
A. Sulfasalzine, B. Steroids, C. Infliximab, D. Cyclosporine
B: Steroids
Answer: B: Steroids 
Explanation: Initial management of ulcerative colitisis is with steroid enema, while many patients will require a sho course of intravenous coicosteroids like methyl-prednisolone. In patients with steroid-refractory colitis, the choice is between rescue medical therapy with cyclosporine or infliximab, or surgery.