This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Which one of the following is an adverse effect associated with combined oral contraceptives: 
Select and explain. 
A. Cerebral stroke, B. Aggravation of asthma, C. Peripheral neuropathy, D. Nephrotic syndrome
A: Cerebral stroke
Answer: A: Cerebral stroke 
Explanation: None