This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Which of the following most significantly increases the risk of hepatocellular carcinoma 
Select and explain. 
A. Hepatitis B virus, B. Hepatitis A virus, C. Cytomegala virus, D. Epstein-Barr virus
A: Hepatitis B virus
Answer: A: Hepatitis B virus 
Explanation: Ans.a. Hepatitis B virus