This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
RDS in Neonate is due to deficiency of? 
Select and explain. 
A. Sphingomyelin, B. Ceramide, C. Dipalmitoyl, D. All of above
C: Dipalmitoyl
Answer: C: Dipalmitoyl 
Explanation: Ans. is 'c' i.e., dipalmitoyl HMD (Respiratory distress syndrome) Primary seen in : PRETERM Baby of diabetic mother Multiple bih LSCS delivery Bih asphyxia Incidence in preterm inversely related to gestational age and bih weight. Primary cause - Surfactant deficiency leads to atelectatic lung. Major constituent of surfactant - la Dipalmitoyl phosphatidylcholine (lecithin) Phosphatidylglycerol A protein Cholesterol Synthesized and stored in type II alveolar cell. X-ray fine granuloreticular pattern with air bronchogram