This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Medicine
Diuretic used in essential hypeension is - 
Select and explain. 
A. Hydrochlohiazide, B. Amiloride, C. Furosemide, D. Acetazolamide
A: Hydrochlohiazide
Answer: A: Hydrochlohiazide 
Explanation: Low dose thiazide diuretics may be used alone or in combination with other anti hypeensive agents . mechanism of action:they inhibit the Na/cl pump in distal convoluted tubule and increase sodium excretion. Drugs used are :Hydrochlohiazide,chlohalidone(long acting and more potent than hydrochlohiazide but potassium loss is greater. ) They provide additive bp lowering effects with ace inhibitors ,arb's, beta blockers. Addition of diuretic to calcium channel blocker is less effective . Ref:Harrison 20 th edition pg no 1901