This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Wigabatrin' a new antiepileptic agent acts by ? 
Select and explain. 
A. GABA- antagonis, B. GABA - agonism, C. NMDA antagonism, D. Carbonic anhydrase inhibition
B: GABA - agonism
Answer: B: GABA - agonism 
Explanation: Ans is 'b' i.e., GABA-agonism o Vigabatrin (y-vinyl GABA) is an inhibitor of GABA transaminase, the enzyme which degrades GABA. o Anticonvulsant action is due to increase synaptic GABA concentration.