This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Ophthalmology
Which of the following is not used in glaucoma in a hypertensive patient – 
Select and explain. 
A. Dipivefrine, B. β–blockers, C. Alpha agonist, D. Trabeculoplasty
C: Alpha agonist
Answer: C: Alpha agonist 
Explanation: Alpha agonists (Brimonidine and apraclonidine) are contraindicated in hypertensive crisis.
Dipivefrin is a prodrug which is converted into epinephrine inside the eyeball, so can safely be used in hypertension.