This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
Which of the following is responsible for non-shivering thermogenesis in adults? 
Select and explain. 
A. Thyroid hormone, B. Brown fat between the shoulders, C. Noradrenaline, D. Muscle metabolism
B: Brown fat between the shoulders
Answer: B: Brown fat between the shoulders 
Explanation: Brown adipose tissue is involved in metabolism, paicularly at times when heat generation is necessary. Thus, the tissue is extremely active in some species, in animals exposed to cold (nonshivering thermogenesis), and in heat production in the newborn. Though not a prominent tissue in humans, it is present in normal individuals, where it could be responsible for "diet-induced thermogenesis." It is reduced or absent in obese persons. The tissue is characterized by a well-developed blood supply and a high content of mitochondria and cytochromes, but low activity of ATP synthase. Metabolic emphasis is placed on oxidation of both glucose and fatty acids. Ref: Botham K.M., Mayes P.A. (2011). Chapter 25. Lipid Transpo & Storage. In D.A. Bender, K.M. Botham, P.A. Weil, P.J. Kennelly, R.K. Murray, V.W. Rodwell (Eds), Harper's Illustrated Biochemistry, 29e.