This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Liver, Subject name: Surgery
Most common extra intestinal manifestation of amoebiasisis 
Select and explain. 
A. Amoebic liver abscess, B. Pleural effusion, C. Atelactasis, D. Cardiac tamponade
A: Amoebic liver abscess
Answer: A: Amoebic liver abscess 
Explanation: Ans. is 'a' i.e., Amoebic liver abscess * Amoebic Ever abscess is the most common extraintestinal manifestation of amebiasis. Disease begins when E. histolytica trophozoites penetrate through the colonic mucosa, travel through the portal circulation, and reach the liver.* Most individuals with amebic liver abscess do not have concurrent signs or symptoms of colitis, and most do not have E. histolytica trophozoites in their stools.* The classic presentations of amebic liver abscess are right-upper-quadrant pain, fever, and hepatic tenderness.* The most common laboratory findings are leukocytosis (without eosinophilia), an elevated alkaline phosphatase level, mild anemia, and an elevated erythrocyte sedimentation rate.