This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: JIPMER 2018, Subject name: Pediatrics
A newborn girl presents with severe Purpura Fulminans. Family has history of 1 year old male died of severe purpura fulminans. Other 2 siblings are normal. What is the diagnosis? 
Select and explain. 
A. Hemophilia A, B. Protein C deficiency, C. ITP, D. vWD
B: Protein C deficiency
Answer: B: Protein C deficiency 
Explanation: Purpura fulminans: Coagulation of the microvasculature, which leads to purpuric lesions and skin necrosis. =3 types: NEONATAL: Hereditary deficiency of protein C, protein S and antithrombin III IDIOPATHIC: Post infectious autoimmune disorder ACUTE INFECTIOUS: most common type- manifests as a skin finding in the most severe septic patients as well as in necrotizing fascitis SINCE the neonate has severe purpura fulminans and family history- answer is protein C deficiency.