This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Surgery
Metabolic abnormality seen in large colorectal villous adenoma 
Select and explain. 
A. Hypokalemic metabolic acidosis, B. Hypokalemic metabolic acidosis, C. Chlorine sensitive metabolic acidosis, D. Chlorine resistant metabolic alkalosis
B: Hypokalemic metabolic acidosis
Answer: B: Hypokalemic metabolic acidosis 
Explanation: .Features of Adenoma * Can be asymptomatic. * Bleeding per anum is usually chronic but rarely can be acute. * Anaemia. * Prolapse--common in tubular type. * Diarrhoea common in villous type; mucus discharge. * Tenesmus, colicky abdominal pain. * Spurious diarrhoea. * Poor general health. * Electrolyte imbalance - hypokalaemia. * Per-rectal examination should be done to feel the adenoma/polyp. * Carcinomatous changes. ref:SRB&;s manual of surgery,ed 3,pg no 832