This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Pathology
C-MYC translocation is seen in which of the following tumors? 
Select and explain. 
A. Burkitt lymphoma, B. Neuroblastoma, C. Malignant melanoma, D. Breast cancer
A: Burkitt lymphoma
Answer: A: Burkitt lymphoma 
Explanation: All forms of Burkitt lymphoma are highly associated with translocation of the MYC gene on chromosome 8 that lead to increased MYC protein levels.The translocation paner for MYC is usually the IgH locus but may also be the Ig . Ref :Robbins pathologic basis of disease ; south east asia edition ;pg:597