This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Which of the following antibodies is positive in Primary Biliary cholangitis (PBC) 
Select and explain. 
A. Anti - nuclear antibody, B. Anti - mitochondrial antibody, C. Anti - smooth muscle antibodies, D. CANCA and PANCA
B: Anti - mitochondrial antibody
Answer: B: Anti - mitochondrial antibody 
Explanation: Anti mitochondrial antibodies are a signature autoantibody of PBC and are detected in sera of  95% patients.