This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
All of the following are prognostic factors of carcinoma endometrium, EXCEPT: 
Select and explain. 
A. Pelvic node involvement, B. Deep myometrial involvement, C. Enlarged uterine cavity, D. Poor differentiation
C: Enlarged uterine cavity
Answer: C: Enlarged uterine cavity 
Explanation: Uterine size is not considered an independent prognostic factor. Prognostic Factors in Endometrial Cancer: Uterine Factors Extrauterine Factors Clinical and Genetic Factors Histologic subtype Lymph node metastasis Age Tumor grade Peritoneal fluid cytologic findings Hormone receptor status Lymphovascular space invasion Histologic cell type Ploidy Myometrial invasion MicrosatRellite instability Cervical extension Oncogenic influence Adnexal metastasis Ref: Suh G.K., Hennessy B.T., Markman M. (2011). Chapter 29. Tumors of the Uterine Corpus. In H.M. Kantarjian, R.A. Wolff, C.A. Koller (Eds), The MD Anderson Manual of Medical Oncology, 2e.