This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: dermatology and infectious disease, Subject name: Pathology
Harlequin ichthyosis is inherited as? 
Select and explain. 
A. Autosomal dominant, B. Autosomal Recessive, C. X Linked dominant, D. X Linked recessive
B: Autosomal Recessive
Answer: B: Autosomal Recessive 
Explanation: Harlequin ichthyosis Harlequin ichthyosis is a rare autosomal recessive disorder in which the neonate is born with a thick covering of armor-like scales, severe ectropion and eclabium, and underdeveloped nose and ears. despite these consistent phenotypic features, a variety of biochemical and structural characteristics have been described. The finding of increased epidermal triglyceride content suggested a lipid defect, but an alteration in keratinization have also been described. Ref: Dermatology at the Millennium(edited by D.Dyall-Smith and R.Marks)page no.583