This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Regarding oncogenesis, all are true except: 
Select and explain. 
A. Proto-oncogenes are activated by chromosomal translocation, B. Malignant transformations involves accumulation of mutations in proto-oncogenes and tumor suppressor genes, C. Point mutation of somatic cells, D. Increase in telomerase activity causes anti-tumor effects
D: Increase in telomerase activity causes anti-tumor effects
Answer: D: Increase in telomerase activity causes anti-tumor effects 
Explanation: Activation of proto-oncogene results in cancer causing oncogenes by following mechanisms: