This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Diseases of orbit, Lids and lacrimal apparatus, Subject name: Ophthalmology
A recurrent Chalazion should be subjected to histopathologic evaluation to exclude the possibility of- 
Select and explain. 
A. Squamous cell carcinoma, B. Sebaceous cell carcinoma, C. Malignant melanoma, D. Basal cell carcinoma
B: Sebaceous cell carcinoma
Answer: B: Sebaceous cell carcinoma 
Explanation: *A recurrent Chalazion in old age should arouse suspicion of malignant change into meibomian gland adenocarcinoma (Sebaceous cell carcinoma). Ref: Kanski 5th/e p.13