This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: NEET 2019, Subject name: Pharmacology
Cilastatin is given in combination with Imipenem because:- 
Select and explain. 
A. Cilastatin prevents degradation of Imipenem in kidney, B. Cilastatin increase absorption of Imipenem, C. Inhibits the enzymes that digest Imipenem in stomach, D. Reduces side effects of Imipenem
A: Cilastatin prevents degradation of Imipenem in kidney
Answer: A: Cilastatin prevents degradation of Imipenem in kidney 
Explanation: Carbapenems are synthetic Beta lactam antibiotic. Imipenem is compounded with cilastatin to protect it from metabolism by renal dehydropeptidase. Cilastatin is a dehydropeptidase inhibitor. High level of imipenem may provoke seizure, however other carbapenem like:- Meropenem Eapenem Doripenem Are less likely to do