This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pharmacology
Which of the following drug is a SERM useful for treatment of osteoporosis? 
Select and explain. 
A. Raloxifene, B. Bisphosphonate, C. Strontium, D. Estradiol
A: Raloxifene
Answer: A: Raloxifene 
Explanation: Ans. (A) Raloxifene(Ref: Katzung, 11/e p759; Goodman and Gilman, 11/e p1557; KDT 8/e p339)Raloxifene is a selective estrogen receptor modulator with estrogen agonistic action on bone and antagonistic action on breast and endometrium. It is therefore the preferred drug for the treatment and prevention of post-menopausal osteoporosis. Major adverse effect of this agent is increased risk of thromboembolism.