This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
Angelman syndrome is due to - 
Select and explain. 
A. Digenic inheritence, B. Inversion, C. Uniparental disomy, D. Mitochondrial disorder
C: Uniparental disomy
Answer: C: Uniparental disomy 
Explanation: Robbins basic pathology 9th edition page no 244 Angelman syndrome, as might be expected, can result from uniparental disomy of parental chromosome 15.