This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
The complications of Down syndrome include: 
Select and explain. 
A. VSD, B. ALL, C. Hypothyroidism, D. All of the above
D: All of the above
Answer: D: All of the above 
Explanation: Complications of Down syndrome are: 

Congenital cardiac defects (Most common is ventricular septal defect). 
Increased risk of leukemia particularly ALL (more commonly) and specifically the megakaryoblastic form of AML (M7-AML). 
Hypothyroidism. 
Reduced fertility in females (Males are totally infertile). 
Increased risk of respiratory tract infections.