This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Glycolysis, Subject name: Biochemistry
Pyruvate kinase is inhibited by - 
Select and explain. 
A. Insulin, B. Fructose -1,6 bisphosphate, C. ATP, D. All of the above
C: ATP
Answer: C: ATP 
Explanation: Ans. is 'c' i.e., ATPPyruvate Kinaseo This enzyme catalyzes conversion of PEP to pyruvate.o Pyruvate kinase is an inducible enzyme that increases in concentration with high insulin level and decreases with glucagon.o It is activated by fructose-1,6 bisphosphate and inactivated by ATP and alanine.