This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Female Genital Tract, Subject name: Pathology
Endometriotic lesion histology represents it's? 
Select and explain. 
A. High estrogen, B. High progesterone, C. High cholesterol, D. High levels of prolactin
A: High estrogen
Answer: A: High estrogen 
Explanation: Ans. (a) High estrogen(Ref: R 9th/p 721)Increased estrogen production by endometriotic stromal cells, due in large part to high levels of the key steroidogenic enzyme aromatase, which is absent in normal endometrial stroma. Mutations in specific genes (PTEN and ARID1A) in endometriotic cysts.