This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti-Arrhythmic, Subject name: Pharmacology
Antiarrhythmic drug causing hypothyroidism is: (E. REPEAT 2007) 
Select and explain. 
A. Lidocaine, B. Propanolol, C. Amiodarone, D. Procainamide
C: Amiodarone
Answer: C: Amiodarone 
Explanation: Ref: Drug-Induced Diseases: Prevention, Detection and Management, James E. Tisdale, 2nd edition, Page 587Explanation:Amiodarone causes both Hypo and Hyperthyroidism.DRUGS CAUSING HYPOTHYROIDISMEthionamide.Amiodarone.Nitroprusside.Perchlorate.Povidone iodine (Betadine).Sulfonylureas.INF alpha.Lithium.Octreotide.Rifampin.Aldesleukin.Thalildomide.Leuprolide.DRUGS CAUSING HYPERTHYROIDISMAmiodarone.Cyclosporine.INF alpha.INF beta.lodinated compounds.Lenalidomide.Leuprolide.Lithium.