This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Pharmacotherapy in psychiatry, Subject name: Anatomy
hyper ammonemia is a side effect of 
Select and explain. 
A. valproate, B. amitriptilline, C. amisulpride, D. olanzapine
A: valproate
Answer: A: valproate 
Explanation: LETHAL SIDE EFFECTS OF VALPROATE - Hyperammonemia - Pancreatitis - Hepatic failure - Neural tube defects - Thrombocytopenia MINOR SIDE EFFECTS OF VALPROATE - Hair loss - PCOD - WEIGHT GAIN - TREMORS Ref.kaplon and sadock, synopsis of psychiatry,11 th editioon, pg no.935