This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti-Cancer, Subject name: Pharmacology
Hand and foot syndrome is seen with: 
Select and explain. 
A. 5- fluorouracil, B. Bleomycin, C. Etoposide, D. Doxorubicin
A: 5- fluorouracil
Answer: A: 5- fluorouracil 
Explanation: Ans. A. 5- fluorouracilHand and land foot syndrome is peculiar feature of 5- fluorouracil. Bleomycin is known to cause pulmonary fibrosis, Etoposide cause alopecia and GIT disturbances. Doxorubicin is highly cardiotoxic drug.