This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Acetyl-CoA generated from the metabolism of fatty acid can be conveed into all of the following, except: 
Select and explain. 
A. Glucose, B. Fatty Acids, C. Cholesterol, D. Ketone bodies
A: Glucose
Answer: A: Glucose 
Explanation: In humans and animals Acetyl-CoA cannot be used to synthesise glucose. Pyruvate or oxaloacetate is needed as the staing material for glucose production gluconeogenesis. Humans and animals do not possess the enzymes needed to conve Acetyl-CoA to pyruvate. Ref: General, Organic and Biological Chemistry By H. Stephen Stoker, Page 943