This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: parasitic infection, Subject name: Medicine
Which of the following is not related to kala azar? 
Select and explain. 
A. Pancytopenia, B. Oral miltefosine, C. Hyperpigmentation, D. Tropical splenomegaly syndrome
D: Tropical splenomegaly syndrome
Answer: D: Tropical splenomegaly syndrome 
Explanation: - Tropical splenomegaly syndrome is now known as Hyperreactive malarial syndrome (HMS) is prevalent in native residents of regions where malaria is endemic.Patients with HMS have high levels of antibody for Plasmodium falciparum, Plasmodium vivax, or Plasmodium ovale. - Presentation of Kala Azar -fever, chills and spleen progressively becomes greatly enlarged, and bone marrow damage leads to pancytopenia. The liver is somewhat enlarged, and generalized lymphadenopathy may occur. Hyperpigmentation of skin can be seen, leading to the name Kala Azar. Oral miltefosine can be used for treatment.(Liposomal Amphotericin B is preferred)