This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
All of the following are true regarding splenectomy in patients with hereditary spherocytosis, except ? 
Select and explain. 
A. Avoid in mild cases, B. Delay splenectomy until at least 4 years old age, C. Anti-pneumococcal vaccination must be given before splenectomy, D. Prolonged anti-pneumococcal antibiotic prophylaxis must be given after splenectomy
D: Prolonged anti-pneumococcal antibiotic prophylaxis must be given after splenectomy
Answer: D: Prolonged anti-pneumococcal antibiotic prophylaxis must be given after splenectomy 
Explanation: Ans. is 'd' i.e., Prolonged Anti-pneumococcal Antibiotic Prophylaxis must be given after splenectomy Splencectomv in patients with Hereditary spherocytosis Avoid splenectomy in mild cases. Delay splenectomy until at least 4 years of age after the risk of severe sepsis has peaked. Anti-pneumococcal vaccination befoe splenectomy is imperative while anti-pneumococcal prophylaxis post-splenectomy is controversial.