This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hemoglobinopathies: Sickle cell anemia, Subject name: Pathology
Coomb's negative condition with spherocytes on peripheral smear amongst the following is: 
Select and explain. 
A. G6PD Deficiency, B. Paroxysmal nocturnal hemoglobinuria, C. Hemolytic disease of newborn, D. AIHA
A: G6PD Deficiency
Answer: A: G6PD Deficiency 
Explanation: - G6PD deficiency is Coomb's -ve condition as it is inherited condition & is not related to antibodies. - Remaining all conditions given in other options are Coomb's positive conditions.