This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General anatomy, Subject name: Anatomy
All of the following cross plasma membrane except 
Select and explain. 
A. Epinephrine, B. Thyroxine, C. Androstenedione, D. Estrogen
A: Epinephrine
Answer: A: Epinephrine 
Explanation: Ref-KDT 6/e p48 Following drug cross plasma membrane Thyroxine Androstenedione Estrogen