This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Oral cavity & Oesophagus, Subject name: ENT
All statement about Plummer Winson syndrome are true except 
Select and explain. 
A. Commonly leads to carcinoma in lower third of oesophagus, B. Common with iron deficiency, C. Common in females, D. Premalignant
A: Commonly leads to carcinoma in lower third of oesophagus
Answer: A: Commonly leads to carcinoma in lower third of oesophagus 
Explanation: Plummer Winson syndrome Classical Features: Dyspahgia Iron Deficiency Anaemia Glossitis Angular Stomatitis Koilonychia Achlorhydria Atrophy of mucous membrane of a the alimentary canal. Predominantly affects females past 40 years Predisposes to development of carcinoma in - Tongue, Buccal mucosa, Pharynx, Esophagus and Stomach. (Ref: Textbook of diseases of ENT, PL Dhingra, 7th edition, pg no. 389)