This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Pharmacology
All the following is characteristic of uncompetitive inhibition except 
Select and explain. 
A. Inhibitor is not a substrate analogue, B. Inhibitor binds to the active site, C. Inhibitor binds to the ES complex, D. Vmax and Km decreased
B: Inhibitor binds to the active site
Answer: B: Inhibitor binds to the active site 
Explanation: An uncompetitive inhibitor binds at a site distinct from the substrate active site and, unlike a competitive inhibitor, binds only to the ES complex. Ref: KD Tripathi 8th ed