This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
Which of the following is granted orphan drug status for the treatment of Dravet’s syndrome? 
Select and explain. 
A. Stiripentol, B. Icatibant, C. Pitolisant, D. Tafamidis
A: Stiripentol
Answer: A: Stiripentol 
Explanation: Stiripentol
Stiripentol increases GABA transmission. It is granted orphan drug status for the treatment of Dravet’s syndrome (Severe myoclonic epilepsy in infants).
Icatibant is a bradykinin B2 receptor antagonist. It is used for acute attacks of hereditary angioedema in adults with C1-esterase inhibitor deficiency.
Pitolisant (a/k/a Tiprolisant) is a inverse agonist of H3 receptor. It is under trial for schizophrenia and Parkinson’s disease.
Tafamidis stabilizes the correctly folded tetrameric form of TTR. It is used in familial amyloid polyneuropathy.