This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
In postmenopausal women, RANK ligand expression is 
Select and explain. 
A. Decreased, B. Increased, C. Same as pre-menopause, D. First decrease to increase later
B: Increased
Answer: B: Increased 
Explanation: In post menopausal women, decreased oestrogen levels lead to increased RANK ligand expression and decreased osteoprotegerin (OPG), resulting in bone resorption.