This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Thioamide drugs: 
Select and explain. 
A. Aggregate endocrine exophthalmos., B. Are safe in children., C. Produce irreversible hypothyroidism., D. Do not produce relapse.
B: Are safe in children.
Answer: B: Are safe in children. 
Explanation: Thioamide drugs block the synthesis of thyroid hormones and are safe in children. If hypothyroidism develops, stopping the drug can reverse it. Despite adequate treatment, relapse is seen in 40-60% of the cases. Worsening of ophthalmopathy has been reported with radioactive iodine but not with thioamides.