This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Dosage of drug is determined by following except ? 
Select and explain. 
A. Volume of distribution, B. Halflife, C. Lipid solubility, D. None
D: None
Answer: D: None 
Explanation: Ans. is 'None' o Loading dose is governed by volume of distribution and volume of distribution is affected by lipid solubility. o Maintenance dose is governed by clearance (excretion) of drug and half life. o For one option go ahead for option b ie half life because : "Clearance is the most impoant factor for maintenance dose".