This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Karyotyping is useful in diagnosis of - 
Select and explain. 
A. Autosomal recessive disorders, B. X-linked recessive disorders, C. Chromosomal abnormalities, D. Biochemical abnormalities
C: Chromosomal abnormalities
Answer: C: Chromosomal abnormalities 
Explanation: Ans. is 'c' i.e., Chromosomal abnormalitieso Karyotyping is the study of chromosomes and is used in cytogenetics to study the chromosomal abnormalities. o After arresting the cells in metaphase the chromosomes are examined to see for:(i) Numbers --> to detect abnormalities in chromosome numbers such as aneuploidy (trisomy, tetrasomy), polyploidy.(ii) Structure ---> to detect structural chromosomal anomalies such as translocations, deletions, inversions.