This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: ANS, Subject name: Pharmacology
Which of the following is most uroselective anticholinergic drug? 
Select and explain. 
A. Darifenacin, B. Tolbutamide, C. Duloxetine, D. Tamsulosin
A: Darifenacin
Answer: A: Darifenacin 
Explanation: Muscarinic anatagonists acting on bladder : SOFT BLADDER S - solifenacin O - Oxybutynin F - Flavoxate T - Tolterodine , Trospium chloride Bladder- Darifenacin Side effects - Urinary Retention Tolbutamide is sulfonylureas , used as a hypoglycemic agent,stimulates the secretion of insulin by the pancreas Duloxetine is used AS SNRI in depression,neuropathic pain ,fibromyalgia etc Tamsulosin is uroselective alpha blocker, used in BPH