This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
Apoptotic bodies are 
Select and explain. 
A. Clumped chromatin bodies, B. Pyknotic nucleus without organelles, C. Cell membrane bound with organelles, D. No nucleus with organelles
C: Cell membrane bound with organelles
Answer: C: Cell membrane bound with organelles 
Explanation: In H&E-stained tissue sections, the nuclei of apoptotic cells show various stages of chromatin condensation and aggregation and, ultimately, karyorrhexis; at the molecular level, this is reflected in fragmentation of DNA into nucleosome-sized pieces. The cells rapidly shrink, form cytoplasmic buds, and fragment into apoptotic bodies composed of membrane-bound vesicles of cytosol and organelles.( Robbins Basic Pathology, 9th edition, page 18 )