This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Urinary tract, Subject name: Pathology
Foot process effacement is seen on EM in - 
Select and explain. 
A. Minimal change disease, B. Focal segmental Glomerulosclerosis, C. IgA nephropathy, D. Mesangial proliferative GN
B: Focal segmental Glomerulosclerosis
Answer: B: Focal segmental Glomerulosclerosis 
Explanation: Disease Pathogenesis Light Microscopy Fluorescence microscopy Electron microscopy Minimal-change disease podocyte injury Normal Negative Effacement of foot processes; no deposits Focal segmental glomerulosclerosis Unknown: reaction to the loss of renal mass. Focal and segmental sclerosis and hyalinosis Usually negative; IgM and C3 may be present in areas of scarring Effacement of foot processes; epithelial denudation Ref: ROBBINS BASIC PATHOLOGY 10th ed Pg no: 556