This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Pharmacology
Effective ulcer treatment that works by inhibitory action on gastric acid secretion is - 
Select and explain. 
A. Lactulose, B. Aluminium hydroxide, C. Sucralfate, D. Ranitidine
D: Ranitidine
Answer: D: Ranitidine 
Explanation: Ans. is 'd' i.e., Ranitidine o Among the given options, only ranitidine decreases acid secretion.Drugs for peptic ulcer1.Reduce gastric acid secretionH2 antihistaminic - Cimetidine, Ranitidine, Famotidine, Roxatidine.Proton pump inhibitors - Omeprazole, Lansoprazole, Pantoprazole, Rabeprazole, Esomeprazole.Anticholinergics - Pirenzepine, propantheline, oxyphenonium.Prostaglandin analogue - Misoprostol, enprostil, rioprostil.2. Neutralization of gastric acid (antacids)Systemic - Sodium bicarbonate, sodium citrate.Non systemic - Magnesium hydroxide, Mag. trisilicate, aluminium hydroxide, Magaldrate, calcium carbonate.3. UlcerprotectivesSucralfate, colloidal bismuth subcitrate, Prostaglandin analogue.4. Anti H. pylori durgsAmoxicillin, clarithromycin, metronidazole, Tinidazole, tetracycline.Note - PG analogue have both antisecretory (i HC1 secretion) as well as cytoprotective action.