This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Autonomic nervous system, Subject name: Pharmacology
A patient complains of muscle weakness it was reversed on administration of neostigmine, because 
Select and explain. 
A. It blocks the action of acetylcholine, B. It interfere with the action of monoamine oxidase, C. It interfere with the action of carbonic anhydrase, D. It interfere with action of acetylcholine esterases
D: It interfere with action of acetylcholine esterases
Answer: D: It interfere with action of acetylcholine esterases 
Explanation: Refer katzung 11e p 105 neostigmine acts by inhibiting the enzyme acetylcholinesteresis This enzyme is involved in the degradation of acetylcholine, consequential neostigmine increases the synaptic level of acetylcholine. Muscle weakness can be improved with the stimulation of Nm receptors at muscle endplate due to increase the acetylcholine