This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Respiratory system, Subject name: Anatomy
Most common cause of mediastinitis is : 
Select and explain. 
A. Tracheal rupture, B. Esophageal rupture, C. Drugs, D. Idiopathic
B: Esophageal rupture
Answer: B: Esophageal rupture 
Explanation: Most cases of acute mediastinitis either are due to esophageal perforation or occur after median sternotomy for cardiac surgery. Ref Harrison 19th edition pg 1719