This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Sclera, Subject name: Ophthalmology
Blue sclera is seen in - 
Select and explain. 
A. Alkaptonuria, B. Osteogenesis imperfect, C. Down syndrome, D. Kawasaki syndrome
B: Osteogenesis imperfect
Answer: B: Osteogenesis imperfect 
Explanation: Ans. is 'b' i.e., Osteogenesis imperfect * Blue scleral discoloration is caused by thinning or transparency with resultant visualization of the underlying uvea.* Causes of blue sclera are: Osteogenesis imperfecta, Marfan syndrome, Ehler - Danlos syndrome, Pseudoxanthoma elasticum.