This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
Regarding intrahepatic cholestasis of pregnancy all are true except 
Select and explain. 
A. More common in multifetal gestation, B. Disappears after delivery, C. Mutation of ABCB4 gene is implicated to cause, D. Usually onset is in Early trimester
D: Usually onset is in Early trimester
Answer: D: Usually onset is in Early trimester 
Explanation: Onset of intrahepatic cholestasis of pregnancy is usually late in pregnancy.