This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
The karyotype of a patient with androgen Insensitivity Syndrome is - 
Select and explain. 
A. 46 XX, B. 46XY, C. 47 XXY, D. 47 XXY
B: 46XY
Answer: B: 46XY 
Explanation: Ans. is 'b' i.e., 46 XY Individual with 'androgen insensitivity syndrome' are XY individuals (male karyotype) with a female phenotype. Mutation in the androgen receptor causes resistance to androgen action and the androgen insensitivity syndrome results.