This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Use of tiotropium is contra–indicated in: 
Select and explain. 
A. Bronchial asthma, B. Hypertension, C. Urinary retention, D. Peptic ulcer disease
C: Urinary retention
Answer: C: Urinary retention 
Explanation: SPIRIVA HANDIHALER (tiotropium bromide inhalation powder) is indicated for the long-term,
once-daily, maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD), 
including chronic bronchitis and emphysema. SPIRIVA HANDIHALER is indicated to reduce exacerbations in COPD patients