This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Classical markers for Hodgkin's disease - 
Select and explain. 
A. CD15 and CD30, B. CD15 and CD22, C. CD15 and CD20, D. CD20 and CD30
A: CD15 and CD30
Answer: A: CD15 and CD30 
Explanation: Classical markers for Hodgkin's disease are CD15 and CD30.
CD15 and CD30 are positive in all variants of Hodgkin's disease except lymphocyte predominance.
Lymphocyte predominance variant is positive for CD20.