This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Moth eaten bone is ? 
Select and explain. 
A. Osteoid osteoma, B. Multiple myeloma, C. Eosinophilic granuloma, D. Chondromyxoid fibroma
B: Multiple myeloma
Answer: B: Multiple myeloma 
Explanation: Ans. is 'b' i.e., Multiple myeloma Patterns of bone destruction present in a lytic lesion ? Geographic : Sharp clearly defined margins. Less aggressive, benign. Eg: non ossifying fibroma, chondromyxoid fibroma, eosinophilic granuloma. Moth eaten appearance : Holes in destroyed bone. Rapid growth, malignant Eg: Myeloma, metastasis, lymphoma. Permeative : Ill defined, diffuse, somewhat subtle destructive process of bone. Eg: Lymphoma, leukemia, Ewing's sarcoma, osteomyelitis.