This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.N.S, Subject name: Pharmacology
No treatment of withdrawal is req uired in - 
Select and explain. 
A. LSD, B. Opium, C. Alcohol, D. Amphetamine
A: LSD
Answer: A: LSD 
Explanation: Ans. is 'a' i.e., LSD o Clinically significant withdrawal syndrome (requires treatment)Alcohol, opioids, amphetamines, Barbiturates, BZDs, Nicotine.o No or minimal clinically significant withdrawal syndrome (requires no treatment) :-LSD (nil). Cannabis (minimal).