This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Sickle Cell Disease, G6PD deficiency and other Hemolytic Anemia, Subject name: Medicine
In sickle cell crisis bone pain is due to: 
Select and explain. 
A. Bone infarction, B. Osteroporosis, C. Osteomalacia, D. Periosteal reaction
A: Bone infarction
Answer: A: Bone infarction 
Explanation: In sickle cell crisis bone pain is due to bone infarction. RBC are sticky, so branching blood vessels gets occluded leading to infarction. "Fish mouth veebra" seen in sickle cell anemia.