This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Medicine
"Menke's disease" is a disease of- 
Select and explain. 
A. Impaired zinc transpo, B. Impaired copper transpo, C. Impaired magnesium transpo, D. Impaired molybdenum transpo
B: Impaired copper transpo
Answer: B: Impaired copper transpo 
Explanation: Menkes kinky hair syndrome is an X-linked metabolic disturbance of copper metabolism characterized by mental retardation, hypocupremia, and decreased circulating ceruloplasmin. This syndrome is caused by mutations in the copper-transpoing ATP7A gene. Children with this disease often die within 5 years because of dissecting aneurysms or cardiac rupture . Ref - Harrisons 20e p2318