This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
JAK-STAT kinase receptors is associated with ? 
Select and explain. 
A. T cAMP, B. IP3 - DAG, C. Ion channels, D. Nuclear transcription
D: Nuclear transcription
Answer: D: Nuclear transcription 
Explanation: Ans. is'd'i.e., Nuclear transcriptionJAK-STAT-Kinase binding receptors:These receptors differ in not having intracellular enzymatic action on receptor itself. Agonist binding induces interaction of these receptors with free intracellular tyrosine kinase - Janus kinase (JAK).jAK phosphorylates activators of transcription (STAT), which then regulate the nucleus transcription resulting in a biological response.Examples -+ Growth hormone, Prolactin,