This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
The most important prognostic factor in breast carcinoma is 
Select and explain. 
A. Histological grade of the tumour, B. Stage of the tumour at the time of diagnosis, C. Status of estrogen and progesterone receptors, D. Over expression of p53 tumor suppressor gene.
B: Stage of the tumour at the time of diagnosis
Answer: B: Stage of the tumour at the time of diagnosis 
Explanation: None