This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
A young boy who has difficulty in getting up from sitting position was diagosed to have Duchene's muscular dystrophy. Which one is true regarding the mutation in the dystrophin gene in promoter region 
Select and explain. 
A. Initiation of transcription to the dystrophin gene would be affected, B. Capping of mRNA of dystrophin gene would be affected, C. Tailing of mRNA of dystrophin gene would be affected, D. Premature termination
A: Initiation of transcription to the dystrophin gene would be affected
Answer: A: Initiation of transcription to the dystrophin gene would be affected 
Explanation: The promoter region of DNA is responsible for initiation of the RNA transcription, hence any mutation in this region is going to effect the initiation process of mRNA synthesis.