This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
Invasive test for shigella is - 
Select and explain. 
A. Dick's test, B. Sereny's test, C. Schick's test, D. Rabbit ileal loop
D: Rabbit ileal loop
Answer: D: Rabbit ileal loop 
Explanation: Ans. is 'd' i.e., Rabbit ileal loop . Enterotoxin (SHET-1 and-2) cause net fluid secretion in ligated ileal loop in vivo and alter electrolyte transpo by gut segments in vitro. . Sereny test is a noninvasive test used for shigella and ETEC --> instillation of a suspension of freshly isolated ETEC or shigella into the eyes of guinea pigs leads to mucopurolent conjuctivitis and severe keratitis.