This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Platelet & Coagulation disorders, Subject name: Medicine
Bleeding crisis in acute idiopathic thrombocytopenic Purpura is managed by all except: 
Select and explain. 
A. RhIG, B. Prednisolone, C. Intravenous immunoglobulin, D. Eltrombopag
D: Eltrombopag
Answer: D: Eltrombopag 
Explanation: Glucocoicoids and IVIg are the mainstays of medical therapy for acute ITP. IV Rh IG in acute ITP also increases platelet count. Thrombopoietin (TPO) receptor agonist eltrombopag interacts with transmembrane domain of human TPO receptor and induces megakaryocyte proliferation and differentiation from bone marrow progenitor cells. It is indicated for thrombocytopenia associated with chronic idiopathic thrombocytopenic purpura and not bleeding crisis.