This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Neuromuscular disorders, Subject name: Orthopaedics
When do you operate for prolapsed disc? 
Select and explain. 
A. Busy executive needs quick surgery, B. Only with weakness no pain, C. Severe pain interfering with activity and not relieved by rest and treatment of 8 weeks, D. Patient of PID with difficulty in ambulation
C: Severe pain interfering with activity and not relieved by rest and treatment of 8 weeks
Answer: C: Severe pain interfering with activity and not relieved by rest and treatment of 8 weeks 
Explanation: Indications for Surgery Absolute indications Relative indications 1. Bladder and bowel involvement 2. Increasing neurological deficit 1. Failure of conservative treatment--Up to 6 weeks of trial is usually given 2. Recurrent sciatica: 1st attack 90% recover 2nd attack 90% recover; 50% recurrent consider surgery 3rd attack 90% recover but all recurrent propose surgery 3. Significant neurological deficit with SLR reduction 4. Disc rupture in stenotic canal 5. Recurrent neurological deficit