This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Medical, surgical and gynaecological illness complicating pregnancy, Subject name: Gynaecology & Obstetrics
At what gestational age should be pregnancy with cholestasis of pregnancy be terminated. 
Select and explain. 
A. 39 weeks, B. 36 weeks, C. 38 weeks, D. 40 weeks
C: 38 weeks
Answer: C: 38 weeks 
Explanation: Antepaum fetal surviellance and delivery at 37-38 weeks is ideal as there is a risk of still bih, fetal distress, meconium stained liqour. Raised levels of serum levels of AST/ALT suggest delivery of the woman at TERM i.e.,. 37-38wks. Refer page no 280 of Text book og obstetrics,sheila balakrishnan,2 nd edition Refer : Textbook of Duttas, 9th edition, page 271. ** Acute fatty liver occurs in late pregnancy