This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Lipid Oxidation and Synthesis, Subject name: Biochemistry
Sandhoffs disease is d/t absence of which enzyme? 
Select and explain. 
A. Beta-hexosaminidase, B. Beta-glucuronibase, C. Arylsulphatase, D. Alpha galactosidase
A: Beta-hexosaminidase
Answer: A: Beta-hexosaminidase 
Explanation: Ans. is 'a' i.e.. Beta-hexosaminidase DiseaseEnzyme deficiencyLipid accumulatedTay-sach diseaseHexosaminidase AGM2 gangliosideSandoff diseaseHexosaminidase BGM2 gangliosideNiemann-Pick diseaseSphingomyelinaseSphingomvelineFarber's diseaseCeramidaseAcyl-sphingosine (ceramide)Fabry's diseasea-galactosidaseGlobotrisylceramideKrabbe's diseaseb-galactosidase (Galactosylceramidase)GaiactosylceramideGaucher's diseaseb-glucosidase (glucocerebrosidase)GlucosylceramideMetachromatic leukodystrophyArylsulfatase A3-Sulfogalactosylceramide