This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Mechanism of action of colchicine in acute gout is 
Select and explain. 
A. Prevention of granulocyte migration, B. Inhibition of leukotriene synthesis, C. Inhibition of uric acid formation, D. Inhibition of purine metabolism
A: Prevention of granulocyte migration
Answer: A: Prevention of granulocyte migration 
Explanation: Colchicine used in acute gout inhibits beta-tubulin protein and prevents granulocyte migration.