This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Medicine
Increased alkaline phosphate are in seen in- 
Select and explain. 
A. Multiple myeloma, B. Primary hyperparathyroidism, C. Chronic renal Mure, D. Osteoporosis
B: Primary hyperparathyroidism
Answer: B: Primary hyperparathyroidism 
Explanation: alkaline phosphate, osteoclastin and type 1 procollagen peptides are markers in primary hyper parathyroid I am( Harrison 17 pg 2382)