This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Glycogen Metabolism and Glycogen Storage, Subject name: Biochemistry
Coris disease is due to defect in - 
Select and explain. 
A. Branching enzyme, B. Debranching enzyme, C. Myophosphorylase, D. Hepatic phosphorylase
B: Debranching enzyme
Answer: B: Debranching enzyme 
Explanation: Ans. is 'b' i.e., Debranching enzyme TypeEnzyme deficiencyOrgan (s) affectedIvon Gierke's diseaseGlucose 6-phosphataseLiver, kidneyIIPompe's diseasea (1 -4) Glucosidase (acid maltase)All organsIIICori's disease/Forbe's diseaseDebranching enzymeMuscle, liverIVAndersen's diseaseBranching enzymeLiver, myocardiumVMcArdle's diseasePhosphorylaseMuscleVIHers' diseasePhosphorylaseLiverVIITarui's diseasePhosphofructokinase.Muscle, RBCsVIII Phosphorylase kinaseLivero There is also on X-linked form of phosphorylase kinase deficiency. This is sole exception as all other glycogen storage diseases are inherited as autosomal recessive trait.