This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Psychiatry
Drug effect mimicking ''Schizophrenia' includes 
Select and explain. 
A. Barbiturates, B. Cocaine, C. Phencyclidine, D. Levodopa
C: Phencyclidine
Answer: C: Phencyclidine 
Explanation: (C) Phencyclidine # PHENCYCLIDINE is an NMDA receptor antagonist also acts as a D2 receptor partial agonist. It induces symptoms that mimic schizophrenia. Amphetamines trigger the release of dopamine and excessive dopamine function is believed to be responsible for many symptoms of schizophrenia.> Cannabis use is also suspected to contribute to the hyperdopaminergic state that is characteristic of schizophrenia.> Drugs such as ketamine, Phencyclidine (PCP), and Lysergic acid diethylamide (LSD) have been used to mimic schizophrenia for research purposes.> Alcohol abuse via a kindling mechanism can occasionally cause the development of a chronic substance induced psychotic disorder, i.e. schizophrenia.