This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
Gonads to testes differentiation – 
Select and explain. 
A. SRY gene, B. WN T–4 gene, C. DAX1 gene, D. None
A: SRY gene
Answer: A: SRY gene 
Explanation: 46 XX chromosome with genetic factor such as DAX1 and signaling molecule WNT-4 are necessary for development of ovary.
Y chromosome contains SRY gene which differentiates gonads to testes.