This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Mendelian Disorders: Single-Gene Defects, Subject name: Pathology
Pataus syndrome due to - 
Select and explain. 
A. Trisomy 21, B. Trisomy 18, C. 18 P, D. Trisomy 13
D: Trisomy 13
Answer: D: Trisomy 13 
Explanation: Ans. is 'd' i.e., Trisomy 13 Trisomv 13 (Patau's syndrome)Head & FaceChestExtremitieso Scalp defects (cutis aplasia )o Congenital heart diseaseo Overlapping of finger &o Microphthalmia, comeal(VSD, PDA, ASD in 80%)toes (Clinodactyly, polydactyly)abnormalitieso Thin posterior ribs (missingo Hypoplastic & hyperconvexo Cleft lip & palate (60-80%)ribs)nailso Microcephaly o Sloping head o Hoioprosencephaly o Capiiary hemangioma o Deafness o Severe developmenal delays & prenatal, postnatal growth retardation & renal abnormalities is seen in trisomy 13.o Only 5% patients of trisomy 13 live more than 6 months.