This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nervous system, Subject name: Physiology
Local anesthetics depress transmission first in 
Select and explain. 
A. Group A alpha-fibers, B. Group A bita-fibers, C. Group B fibers, D. Group C fibers
D: Group C fibers
Answer: D: Group C fibers 
Explanation: Local anesthetics depress transmission in the group C fibre before they affect group A touch fibres. Ref: Ganong&;s Review of medical physiology;25th edition; pg: 95.