This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
All of the following are true regarding Guillain-Barre syndrome except: March 2008 
Select and explain. 
A. Peripheral nervous system is affected, B. Histologically there is inflammation of peripheral nerv, C. Descending paralysis, D. Elevated CSF proteins
C: Descending paralysis
Answer: C: Descending paralysis 
Explanation: Ans. C: Descending paralysis Guillain-Barre syndrome, a disease of the peripheral nervous system, is characterized by weakness beginning in the distal limbs but rapidly advancing to affect proximal muscle function ("ascending paralysis"), and histologically by inflammation and demyelination of spinal nerve roots and peripheral nerves (radiculoneuropathy). There is elevation of the CSF protein due to inflammation and altered permeability of the microcirculation within the spinal roots as they traverse the subarachnoid space. Inflammatory cells are contained within the roots, however, and there is little to no CSF pleocytosis.