This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
True about Mafenide : 
Select and explain. 
A. Can penetrate eschars, B. Doesn't cause burning sensation when applied to raw surface, C. Can be used orally, D. May cause metabolic acidosis
D: May cause metabolic acidosis
Answer: D: May cause metabolic acidosis 
Explanation: Ans. D, May cause metabolic acidosisMafenide:Typical sulpHonamide.Used only totally-inhibits a variety of gram-positive and gram-negative bacteria.Biggest limitation - Produces burning sensation and severe pain when applied to raw surface.Mainly employed for bunt dressing to prevent infection, but not to heat already infected cases.