This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Investigation of choice in case of a pt. with episodic hypertension, headache and thyroid nodule - 
Select and explain. 
A. Urinary HIAA, B. Urinary catecholomine and aspiration of nodule, C. Thyroid function test only, D. Urinary basic amino acid metabolite
B: Urinary catecholomine and aspiration of nodule
Answer: B: Urinary catecholomine and aspiration of nodule 
Explanation: This pt is having MEN type II syndrome which is characterized by
Pheochromocytoma and
Medullary carcinoma of thyroid (MCT)
Urinary catecholamines are increased in pheochromocytoma
Aspiration of nodule will show amyloid material (seen in MCT)