This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General obstetrics, Subject name: Gynaecology & Obstetrics
A woman with H/o recurrent aboions presents with isolated Increase in APTT. Most likely cause is: 
Select and explain. 
A. Lupus anticoagulant, B. Factor VII, C. Von willebrand's disease, D. Hemophilia A
A: Lupus anticoagulant
Answer: A: Lupus anticoagulant 
Explanation: The combination of either anticardiolipin and lupus anticoagulant antibodies with or more of the charecteristic clinical features like thrombosis or recurrent pregnancy loss is termef as antiphosholipid syndrome. Refer page no 333 of Text book of obsteics,sheila balakrishnan,2 nd edition