This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Respiratory, Subject name: Medicine
Characteric finding in restrictive lung disease is: 
Select and explain. 
A. Decreased FEV1, B. Increased TLC, C. Normal FEV1/VC, D. All
C: Normal FEV1/VC
Answer: C: Normal FEV1/VC 
Explanation: Ans. c (Normal FEV, /Vc). (Ref. Harrison, Principles of Medicine, 18th/1448)OBSTRUCTIVE PATTERNRESTRICTIVE PATTERN (Al 2005)EXTRAPARENCHYMAL PATTERN (INSPIRATORY DYSFUNCTION)Decreased expiratory flow rates (hallmark)Normal forced expiratory flow ratesExpiratory flow rates not affectedDecreased FEV1/VC (in fully established disease)-FEVl/FVC variableTLC normal or increased (Minor change)Decreased lung violume (TLC and VC)TLC not predictableIncreased residual volume (striking)Decreased residual volumeIncreased RVIncresed ratio of RV/TLC--Decreased VC-Decreased MIP