This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.N.S, Subject name: Pharmacology
Typical antidepressant drug is: 
Select and explain. 
A. Amitriptyline, B. Clozapine, C. Olanzapine, D. Trazodone
A: Amitriptyline
Answer: A: Amitriptyline 
Explanation: Ans. A. AmitriptylineTypical antidepressant act via inhibiting the reuptake of serotonin and nor epinephrine. Drugs which comes under typical antidepressant are Tricyclic antidepressant, selective serotonin reuptake inhibitor, selective norepinephrine inhibitor and MAO inhibitor. Amitriptyline and imipramine is TCA. Venlafaxine and duloxetine is SNRI. Fluoxetine and duloxetine are SSRI.