This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
In glycolysis, the first committed step is catalysed by- 
Select and explain. 
A. a) 2, 3 DGP, B. b) Glucokinase, C. c) Hexokinase, D. d) Phosphofructokinase
D: d) Phosphofructokinase
Answer: D: d) Phosphofructokinase 
Explanation: Phosphofructokinase catalyzes the commited step of glycolysis, meaning that once fructose l, 6 - bisphosphate is formed it must go for the glycolytic pathway only