This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Drug used for prophylaxis of rheumatic hea disease: March 2011 
Select and explain. 
A. Sulfadiazine, B. Phenoxy-methyl penicillin, C. Benzathine penicillin, D. All of the above
D: All of the above
Answer: D: All of the above 
Explanation: Ans. D: All of the above Patients with acute rheumatic fever are susceptible to fuher attacks of the rheumatic fever if another streptococcal infection occurs, and a long term prophylaxis with penicillin should be given as benzathine penicillin 1.2 million U I/ M monthly or oral phenoxymethylpenicillin 250 mg 12 hourly Sulfadiazine or erythromycin may be used if patient is allergic to penicillin