This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Smooth Muscle: Contraction and Excitation, Subject name: Physiology
Which among the following is a feature of denervation of smooth muscle? 
Select and explain. 
A. Atrophy of the muscle., B. Decrease in no of receptors for neurotransmitters, C. Increased sensitivity to chemical mediators, D. Decreased neurotransmitter release At NMJ
C: Increased sensitivity to chemical mediators
Answer: C: Increased sensitivity to chemical mediators 
Explanation: ANSWER: (C) Increased sensitivity to chemical mediatorsREF: Ganong physiology 22nd edition page 111"When the motor Nerve supply to a smooth muscle is cut, the muscle does not atrophy (this is in contrast to skeletal muscle which atrophies on denervation), It becomes hyper responsive to the chemical mediators that normally activate it"