This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Anatomy
What is the basis for the formation of Omphalocele? 
Select and explain. 
A. Excessive length of the intestine, B. Physiological hernia failing to go back, C. Herniation of liver, D. Herniation of umbilicus
B: Physiological hernia failing to go back
Answer: B: Physiological hernia failing to go back 
Explanation: Omphalocele is protrusion of abdominal contents through the umbilical ring. It is due to failure of physiological hernia to reduce into the abdominal cavity , which results in non-closure of the umbilical ring. An Omphalocele may contain stomach, liver and intestines. And these contents are enclosed in a sac. Omphalocele is usually associated with other congenital anolamies (Eg; trisomy 13, trisomy 18, or Beckwith- Widemann syndrome) and with increased levels of a-fetoprotein. Ref: Gray&;s Anatomy 41st edition Pgno: 1081