This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Regarding trastuzumab, all of the following are true except : 
Select and explain. 
A. Shows better response in combination with paclitaxel, B. Used in non-metastatic breast cancer, C. Causes upregulation of HER2/neu, D. Do not cause bone marrow toxicity
C: Causes upregulation of HER2/neu
Answer: C: Causes upregulation of HER2/neu 
Explanation: None