This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.V.S, Subject name: Pharmacology
ACE inhibitors are contraindicated in: 
Select and explain. 
A. Diabetes mellitus, B. Hypertension in old age groups, C. Scleroderma, D. Bilateral renal artery stenosis
D: Bilateral renal artery stenosis
Answer: D: Bilateral renal artery stenosis 
Explanation: Ans. d (Bilateral renal artery stenosis). (Ref. Pharmacology by KD Tripathi - 5th/- 453)SIDE EFFECTS OF CAPTOPRIL# Cough- - most common - dry hacking - seen in 5-15% of patients - due to accumulation of bradykinin & substance P. # Angioedema * Proteinuria (Nephrotic syndrome) # Teratogenic - Acute renal failure - Growth retardation ----(Mnemonic: CAPTOPRIL)- Hypocalvaria - Hypoplastic bones Most teratogenic -Enalapril # HypOtension # Potassium (Hyperkalemia) # Rash, allergy & Granulocytopenia. # Insufficiency {Renal) (in bilateral renal artery stenosis) # Loss of taste sensation (Dysguasia). - Highest with captopril among these inhibitors.-