This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
What is the most impoant role of bradykinin in acute inflammation- 
Select and explain. 
A. Increase in vascular permeability, B. Vasodilatation, C. Mediation of pain, D. Bronchoconstriction
A: Increase in vascular permeability
Answer: A: Increase in vascular permeability 
Explanation: Functions of Bradykinin: Increases vascular permeability Contraction of smooth muscles Dilation of the blood vessels Pain when injected into the skin Out of these actions of bradykinin, the increase in vessel permeability is a better answer as it is the hallmark of acute inflammation ref robbins9th ed page 52