This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
All are true about succinate dehydrogenase deficient gastrointestinal stromal tumor (SDH-deficient GIST) except 
Select and explain. 
A. More common in children and young adult, B. Negative for DOG-1, C. Most common location is stomach, D. Associated with Carney-Stratakis syndrome
B: Negative for DOG-1
Answer: B: Negative for DOG-1 
Explanation: Answer- B. Negative for DOG-1Succinate dehydrogenase (SDH) deficient - Gastrointestinal Stromal Tumors (GIST)-Pathological features-SDH deficient - GISTs do not have c-KIT mutation --> absence of c-KIT mutation.They strongly express KIT and DOG1/Ano-1, but do not have KIT mutation.Clinical features-They maY be associated with :-Carney stratakis syndrome - Paraganglioma with familial GISTCarney triadThese tumors have tendency to appear in children and young adultsThey occur exclusively in stomach.