This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetic Approach to Pediatric Medicine, Subject name: Pediatrics
Mousy urine in a child is due to defect in conversion of phenlylalanine to - 
Select and explain. 
A. Tyrosine, B. Homogentisic acid, C. Phenyl acetate, D. Phenyl pyruvate
A: Tyrosine
Answer: A: Tyrosine 
Explanation: Ans. is A. Tyrosine Defect in conversion of phenlylalanine to has been asked hence it's tyrosine . If mousy odour is due to is asked then answer will be phenyl acetate . Phenylketonuria o Autosomal recessive o Deficiency of phenylalanine hydroxylase. o Defect in conversion of phenylalanine to tyrosine. o This leads to increase level of phenylalanine, o This increase phenlylalanine converted into phenylpyruvate and phenyl acetate, o This phenyl acetate gives mousy or musty odour in urine/body.