This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Renal angiomyolipoma is associated with: 
Select and explain. 
A. Tuberous sclerosis, B. Neurofibromatosis 1, C. Neurofibromatosis 2, D. All of the above
A: Tuberous sclerosis
Answer: A: Tuberous sclerosis 
Explanation: Angiomyolipomas are present in 25% to 50% of patients with tuberous sclerosis, a disease caused by loss-of-function mutations in the TSC1 or TSC2 tumor suppressor genes. This is a benign tumor consisting of vessels, smooth muscle, and fat. It is characterized by lesions of the cerebral coex that produce epilepsy and mental retardation, a variety of skin abnormalities, and unusual benign tumors at other sites, such as the hea. Ref: Robbins 8th edition Chapter 20.