This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Medicine
Cushing's disease presents with- 
Select and explain. 
A. IncreasedACTH and increased Coisol, B. Decreased ACTH and decreased Coisol, C. IncreasedACTH and decreased Coisol, D. Increased catecholamines
A: IncreasedACTH and increased Coisol
Answer: A: IncreasedACTH and increased Coisol 
Explanation: increased production of coisol by adrenals and bilateral adrenal hyperplasia due to hyper secretion of pituitary ACTH( Harrison 17 pg 2255)