This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General Pharmacology, Subject name: Pharmacology
Zero order kinetics occur in following drug with high dose: 
Select and explain. 
A. Phenytoin, B. Digoxin, C. Amiloride, D. Lithium
A: Phenytoin
Answer: A: Phenytoin 
Explanation: Ans. A. PhenytoinZero order kinetics is due to saturation of metabolizing enzymes i.e. enzymes reach their Vmax Eg (Zero WATT power)ZeroW-Warfarin,A-Alcohol,T-Theophylline,T-Tolbutamide,Power-Phenytoin,Other - Salicylates, omeprazole