This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Pancreas, Subject name: Surgery
Most common genetic mutation in Ca pancreas 
Select and explain. 
A. KRAS, B. p-16, C. P53, D. COX - II
A: KRAS
Answer: A: KRAS 
Explanation: MC genetic mutation in Ca pancreas/ Cholangiocarcinoma - KRAS > p-16 MC genetic mutation in Ca- GB - P53 > K-RAS MC genetic mutation in Ca stomach - P53 > COX - II