This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
A five-year-old boy presents with precocious puberty and blood pressure of 130/80 mmHg Estimation of which of the following will help in diagnosis – 
Select and explain. 
A. ↑17 hydroxy-progesterone, B. ↑ Cortisol, C. ↑Aldosterone, D. ↑ 11 deoxycortisol
D: ↑ 11 deoxycortisol
Answer: D: ↑ 11 deoxycortisol 
Explanation: At the age of 5-6 years, BP in excess of 115/75 mm Hg is considered as hypertension (This boy has BP 130/80).
So, the boy in this question has : -


Precocious puberty
Hypertension


Precocious puberty in male, with salt retention and hypertension, occurs due to deficiency of 11-β Hydroxylase which catalyzes the conversion of 11 deoxycortisol to cortisol.