This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General anatomy, Subject name: Anatomy
Amyloidosis is most commonly seen in 
Select and explain. 
A. Maturity onset DM, B. Type1DM, C. Type2DM, D. Equally seen with all forms of DM
C: Type2DM
Answer: C: Type2DM 
Explanation: Ref Robbins 8/e p253; 9/e p259 Amyloid replacement of islets is a characteristics finding in individual with long standing type 2 diabetes .it is believed that the islet amyloid protein is directly cytotoxic to isletsanalogous to the role played by amyloid plaques implicated in the pathogenesis of Alzheimer's disease