This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of lipid, Subject name: Biochemistry
Desired ratio of total cholesterol/HDL should be 
Select and explain. 
A. <7.5, B. <10, C. <3.5, D. <4.5
C: <3.5
Answer: C: <3.5 
Explanation: HDL-cholesterol level HDL level above 60 mg/dl protects against hea disease. Hence HDL is "good" cholesterol. A level below 40 mg/dl increases the risk of CAD. For every 1 mg/dl drop in HDL, the risk of hea disease rises 3%. If the ratio of total cholesterol / HDL is more than 3.5, it is dangerous. Similarly, LDL: HDL ratio more than 2.5 is also detrimental.Ref: DM Vasudevan - Textbook of Biochemistry, 8th edition, page no: 295