This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
Deficiency in globin synthesis - 
Select and explain. 
A. Thalassemia, B. Sickle cell disease, C. Hereditary spherocytosis, D. sideroblastic anemia
A: Thalassemia
Answer: A: Thalassemia 
Explanation: Ans. is 'a' i.e., Thalassemia Thalassemia Syndromeso The thalassemia syndromes are a heterogeneous group of disorders caused by inherited mutations that decrease the synthesis of either the a-globin or b-globin chains that compose adult hemoglobin, HbA (a2b2), leading to anemia, tissue hypoxia, and red cell hemolysis related to the imbalance in globin chain synthesis.DisorderDefectThalassemiaDeficient Globin SynthesisHereditary SpherocytosisInherited red cell membrane defectSickle Cell DiseaseStructurally abnormal hemoglobin (hemoglobinopathy)