This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hematology, Subject name: Pharmacology
Drug used in heparin overdose is: 
Select and explain. 
A. Protamine sulfate, B. Phylloquinone, C. Ticlopidine, D. Clopidogrel
A: Protamine sulfate
Answer: A: Protamine sulfate 
Explanation: In heparin overdose an antagonist is needed to arrest it&;s anticoagulant effects. Protamine sulphate given IV (1mg for every 100 units of heparin) neutralizes heparin. From medical pharmacology padmaja 4th edition Page no 337