This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.N.S, Subject name: Pharmacology
Treatment of Acute Barbiturate poisoning includes which of the following? 
Select and explain. 
A. Forced alkaline diuresis, B. Acidification of urine, C. Penicillamine administration, D. CaNa EDTA administration
A: Forced alkaline diuresis
Answer: A: Forced alkaline diuresis 
Explanation: Ans. is 'a' i.e., Forced Alkaline diuresis Acute barbiturate poisoning* It is mostly suicidal, sometimes accidental.* Manifestations are due to excessive CNS depression - patient is flabby and comatose with shallow and failing respiration, fall in BP and cardiovascular collapse, renal shut down, pulmonary complications and bullous eruption (barbiturate blisters).* Treatment:i) Gastric lavageii) Supportive measures (O2, assissed respiration, maintenance of BP).iii) Haemodialysisiv) Forced alkaline diuresis