This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Antenatal Screening, Subject name: Gynaecology & Obstetrics
Patient with NTD, dose of folic acid in next pregnancy - 
Select and explain. 
A. 0.5 mg, B. 1 mg, C. 2 mg, D. 4 mg
D: 4 mg
Answer: D: 4 mg 
Explanation: Ans. is 'd' i.e., 4mg o The recurrence risk of neural tube defect is:# 3 - 5 % if a couple has previously had a child with either anencephaly or spina bifida.# 5% if either parent was bom with a NTD# 10% if a couple has two affected children.o Folic acid supplementation 4 mg daily 1 month before conception to about 12 weeks of pregnancy.