This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Anatomy
In cholecytectomy of cirrhotic patient , fresh frozen plasma should be given 
Select and explain. 
A. Just before operation, B. At the time of operation, C. 6 hours before operation, D. 12 hours after operation
A: Just before operation
Answer: A: Just before operation 
Explanation: A cirrhotic patient with abnormal coagulation who needs cholecystectomy should be given FFP FRESH FROZEN PLASMA Transfusions with FFP are given to replenish clotting factors The effectiveness of the transfusion in maintaining hemostasis is dependent on the quantity of each factor delivered and its half life The half-life on the most stable clotting factor, FACTOR-VII, is 4 to 6 hours A reasonable transfusion scheme would be to give FFP on call to the operating room. This way the transfusion is complete prior to the incision, with circulating factors to cover the operative and immediate post-op period Ref: Sabiston 20th edition Pgno :1496