This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Parathyroid and adrenal glands, Subject name: Surgery
A young female with history of renal calculi complains of bone pain and abdominal cramps. On investigation, multiple fractures were discovered and serum calcium and PTH was raised. Which of the following will be the best investigation to arrive at a definitive diagnosis? 
Select and explain. 
A. CECT neck, B. Sestamibi scan, C. Radioiodine scan, D. Ultrasound neck
B: Sestamibi scan
Answer: B: Sestamibi scan 
Explanation: Hyperparathyroidism Patient with PHPT formerly presents with classic pentad of symptoms Kidney stones Psychic moans Painful bones Fatigue oveones Abdominal groans -Biochemical findings - increase Serum Ca++ ,Increase PTH -MC cause is single adenoma Best investigation to localize parathyroid Adenomas - Sestamibi scan