This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: viral infection, Subject name: Medicine
Most common extra-cutaneous manifestation of chicken pox in children is: 
Select and explain. 
A. CNS involvement, B. Varicella pneumonia, C. Congenital varicella, D. Reye syndrome
A: CNS involvement
Answer: A: CNS involvement 
Explanation: The most common extracutaneous site of involvement in chicken pox in children is the CNS. CSF contains lymphocytes and elevated levels of protein. CNS involvement is a benign complication of VZV infection in children and generally does not require hospitalization. Aseptic meningitis, encephalitis, transverse myelitis, and Guillain-Barre syndrome can also occur.