This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Skin
Acrodermatitis enteropathica is associated with deficiency of? 
Select and explain. 
A. Zinc, B. Molybdenum, C. Vitamin B12, D. Free fatty acids
A: Zinc
Answer: A: Zinc 
Explanation: Ans is 'a' i.e. Zinc * Acrodermatitis enteropathica (AE) is an autosomal recessive inborn error of zinc metabolism that is associated with mutations in a gene encoding the zinc transporter protein, leading to decreased zinc uptake.* It is associated with periorificial and acral dermatitis, diarrhea, behavioral changes, and neurologic disturbances. In older children, zinc deficiency is characterized by failure to thrive, anorexia, alopecia, nail dystrophy, and repeated infections.* Skin involvement may present withi) Blistering & erosionsii) Dry skiniii) Glossitisiv) Pustules