This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: JIPMER 2018, Subject name: Pharmacology
Axicabtagene ciloleucel is used in: 
Select and explain. 
A. Relapsed myeloma, B. T cell lymphoma, C. Diffuse large B cell lymphoma, D. Small cell lung Ca
C: Diffuse large B cell lymphoma
Answer: C: Diffuse large B cell lymphoma 
Explanation: CAR T-cell therapy:- A type of treatment in which a patients T cell are changed in laboratory so they will bind to cancer cells and kill them.Blood from a vein in Patient's arm flow through a tube to an apheresis machine, which removes the T cell and sends rest of blood back to the patient. CAR T cell are grown in the lab. The CAR T cell are able to bind to antigen on cancer cell and kill them. There are 2 FDA approved CAR T cell therapies:- Axicabtagene ciloleucel- Tisagenlecleucel Axicabtagene ciloleucel is use for diffuse large B cell lymphoma