This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
True about Pralidoxime ? 
Select and explain. 
A. It acts by regenerating acetylcholinesterase enzyme, B. It can be used for all chlorinated compounds, C. It is not used for war gases, D. Plasma cholinesterase levels signifies better reflection of enzyme activity than RBC levels
A: It acts by regenerating acetylcholinesterase enzyme
Answer: A: It acts by regenerating acetylcholinesterase enzyme 
Explanation: Ans. is 'a' i.e., It acts by regenerating acetylcholinesterase enzyme Pralidoxime (and other oximes) acts by reactivating cholinesterase enzyme. Oximes are used for poisoning with organophosphate insectide not for chlorinated insectisides (chlorinate hydrocarbons e.g. DDT, lindane, dieldrin). Some of the war gases are organophosphate compounds e.g. dialkylfuorophosphate, for which oximes can be used. RBC cholinesterase levels reflect enzyme activity better than plasma cholinesterase because: i) Plasma cholinesterase can give falsly high activity if there is RBC hemolysis (RBC cholinesterase comes into plasma) ii) In chornic organophosphate exposure, plasma cholinesterase may return to normal but RBC levels remains depressed.