This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
The most indicative test for prostate cancer is: 
Select and explain. 
A. A thorough digital rectal examination, B. Magnetic resonance imaging (MRI), C. Excretory urography, D. Prostate-specific antigen
D: Prostate-specific antigen
Answer: D: Prostate-specific antigen 
Explanation: An elevated prostate-specific antigen level indicates prostate cancer, but it can be falsely elevated if done after the prostate gland is manipulated.

Option A: A digital rectal examination should be done as part of the yearly screening, and then the antigen test is done if the digital exam suggests cancer.
Option B: MRI is used in staging the cancer.