This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Systemic Lupus Erythematous, Subject name: Medicine
Onion skin spleen is seen in: 
Select and explain. 
A. ITP, B. Thalassemia, C. SLE, D. Scleroderma
C: SLE
Answer: C: SLE 
Explanation: Three histological lesions are most characteristic of SLE Onion skin lesion of splenic aery Libman sacks endocarditis Hematoxylin bodies Onion skin pattern is seen in: Splenic aery in SLE Ewing sarcoma Charcot marie tooth disease Primary sclerosing cholangitis Malignant HTN