This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Malabsorbtion Syndrome, Subject name: Medicine
All are diagnostic criteria for irritable bowel syndrome except: 
Select and explain. 
A. Pain improves with defection, B. Nocturnal episodes of colicky pain, C. Onset associated with change in frequency of stool, D. Onset associated with change in appearance / form of stool
B: Nocturnal episodes of colicky pain
Answer: B: Nocturnal episodes of colicky pain 
Explanation: The diagnostic criteria for irritable bowel syndrome is - Recurrent abdominal pain or discomfo for at least 3 days per month associated with > 2 or more of the following features - Pain improvement with defecation Onset with change in form / appearance of stool Onset with change in frequency of stool Nocturnal diarrhea or pain is not a feature of irritable bowel syndrome and is seen with Diabetic neuropathy. Bleeding is also not a feature. ROME CRITERIA FOR DIAGNOSIS OF IBS