This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
The inheritance pattern of familial retinoblastoma 
Select and explain. 
A. Autosomal recessive, B. Autosomal dominant, C. X linked recessive, D. X linked dominant
D: X linked dominant
Answer: D: X linked dominant 
Explanation: In hereditary retinoblastoma, mutations in the RB1 gene appear to be inherited in an autosomal dominant pattern. Autosomal dominant inheritance means that one copy of the altered gene in each cell is sufficient to increase the risk of cancer. Refer robbins 1339