This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
True about chaperone? 
Select and explain. 
A. Also known as HS proteins, B. Have ATPase activity, C. Always bind to specific areas on unfolded proteins, D. They always acts as foldases
A: Also known as HS proteins
Answer: A: Also known as HS proteins 
Explanation: Ans. is 'a' i.e., Also known as HS proteinsChaperones are proteins which help in folding or unfolding of proteins Molecular chaperones prevent aggregation and promote refolding after stress and hence promote cell survival. This so-called stress response is ubiquitous and conserved across all organisms. Hence Chaperones are otherwise known as heat shock proteins (HSP)Chaperones are synthesized in response to heat and other stress conditions like exposure to heavy metals, UV radiation, oxidative stress, nutrient deficiencies, dehydration, osmotic pressures and viral infections. Hence, they are otherwise called as stress proteins