This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Karyotyping is done in which phase of cell cycle 
Select and explain. 
A. Anaphase, B. Metaphase, C. Telophase, D. S phase
B: Metaphase
Answer: B: Metaphase 
Explanation: Ans. is 'b' i.e., Metaphase o To produce a karyotype, one must obtain cells capable of growth and division as karyotyping is done by arresting mitosis in dividing cells in metaphase