This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Pathology
The type of mutation that leads to replacement of Valine for glutamate in Sickle Cell Disease is 
Select and explain. 
A. Point mutation, B. Silent mutation, C. Nonsense mutation, D. None
A: Point mutation
Answer: A: Point mutation 
Explanation: .