This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Centrilobular zonal necrosis in liver is seen with which of the following drug? 
Select and explain. 
A. Carbon tetrachloride, B. Rifampicin, C. INH, D. Yellow phosphorus poisoning
A: Carbon tetrachloride
Answer: A: Carbon tetrachloride 
Explanation: Carbon tetrachloride characteristically produce a centrilobular zonal necrosis, whereas yellow phosphorus poisoning typically results in peripoal injury. Ref: Harrisons Principles of Internal Medicine, 18th Edition, Page 2558.