This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Burns, Subject name: Surgery
Which of the following statement(s) is/are true concerning topical antimicrobials in common use today? 
Select and explain. 
A. Of the common topical antimicrobials, only mafenide acetate is painful upon application, B. The use of 0.5% silver nitrate is associated with trans-eschar leeching of sodium and potassium from the wound, C. Silver sulfadiazine, mafenide acetate, and 0.5% silver nitrate all have a broad spectrum activity, however, only silver nitrate has anti-fungal activity, D. All of the above
D: All of the above
Answer: D: All of the above 
Explanation: THREE COMMON TOPICAL MEDICATIONS USED Silver sulfadiazine Mafenide acetate 0.5% Silver nitrate Painless on application Fair to poor eschar penetration No metabolic side effects Broad antibacterial spectrum Painful on application Excellent eschar penetration Carbonic anhydrase inhibitor Broad-spectrum antibacterial Painless on application Poor eschar penetration Broad-spectrum antibacterial and antifungal