This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nose and PNS, Subject name: ENT
Black necrotic mass seen in the nose of a elderly diabetic patient. Most probable diagnosis - 
Select and explain. 
A. Lupus vulgaris, B. Aspergillosis, C. Mucormycosis, D. Pseudomonas infection
C: Mucormycosis
Answer: C: Mucormycosis 
Explanation: Ans. is 'c' i.e., Mucormycosis o Mucormycosis is fungal infection of nose and paranasal sinuses which may prove rapidly fatal if untreated.o It is seen in uncontrolled diabetics or in those taking immunosuppressive drugs.o From the nose and sinuses, infection can spread to orbit, cribriform plate, meninges and brain.o The rapid destruction associated with the disease is due to affinity of fungus to invade the arteries and cause endothelial damage and thrombus.o It presents as black necrotic mass filling the nasal cavity and eroding the septum and hard palate.o Treatment is by amphotericin B and surgical debridement.