This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pharmacology, Subject name: Pharmacology
After I.V. drug administration, elimination of a drug depends on 
Select and explain. 
A. Lipid solubility, B. Volume of distribution, C. Clearance, D. All of the above
D: All of the above
Answer: D: All of the above 
Explanation: if a drug is highly lipid soluble it is unionized-easily eliminated if vd is more, elimination is difficult if clearance is good, elimination is easy Pg.no 30 KD TRIPATHI SEVENTH EDITION