This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Which of the following drugs is associated with the untoward side effect of renal tubular damage? 
Select and explain. 
A. Cisplatin, B. Streptozocin, C. Methysergide, D. Cyclophosphamide
A: Cisplatin
Answer: A: Cisplatin 
Explanation: Cisplatin is a highly emetic and nephrotoxic agent.
Streptozocin causes the destruction of β-cells of the pancreas and may result in hyperglycemia.
Methysergide can cause retroperitoneal fibrosis on long-term use.
Cyclophosphamide can result in hemorrhagic cystitis.