This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Which of the following is the most potent glucocoicoid: March 2010 
Select and explain. 
A. Hydrocoisone, B. Prednisolone, C. Betamethasone, D. Triamcinolone
C: Betamethasone
Answer: C: Betamethasone 
Explanation: Ans. C: Betamethasone Betamethasone and dexamethasone are very potent and highly selective glucocoicoids. Long acting, causes marked pituitary-adrenal suppression, but fluid retention and hypeension is not a problem. Hence they are preferred in situations in which fluid retention must be avoided like cerebral edema.