This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Which tooth in the permanent dentition is the most
susceptible to dental caries? 
Select and explain. 
A. Maxillary 1st premolar, B. Maxillary 2nd molar, C. Mandibular 1st molar, D. Mandibular 2nd molar
C: Mandibular 1st molar
Answer: C: Mandibular 1st molar 
Explanation: None