This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Pediatrics
Which of the following is the major site of erythropoietin production during the fetal stage? 
Select and explain. 
A. Liver, B. Yolk sac, C. Bone, D. Spleen
A: Liver
Answer: A: Liver 
Explanation: Erythropoietin is produced in the fetal liver in the first and second trimester.After bih, the major site of production is in the kidney.(Refer: Nelson's Textbook of Pediatrics, SAE, 1st edition, pg no. 2305 - 2306)