This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
Delayed puberty is seen in 
Select and explain. 
A. Hypothyroidism, B. Turnur's syndrome, C. Malabsorbtion syndrome, D. Chronic disease
D: Chronic disease
Answer: D: Chronic disease 
Explanation: Delayed puberty may be related to chronic, reversible causes like systemic disease, malnutrition,eating disorders,hyperprolactinemia,and hypothyroidism.Irreversible defects include the destruction of the hypothalamic-pituitary axis by infection, surgery, tumour. All these are due to chronic disease.