This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.N.S, Subject name: Pharmacology
Vigabatrin acts through - 
Select and explain. 
A. decreasing GABA uptake at synaptic cleft, B. Increasing GABA uptake at synaptic cleft, C. GABA transaminase inhibitor, D. GABA transacetylase inhibitor
C: GABA transaminase inhibitor
Answer: C: GABA transaminase inhibitor 
Explanation: Ans. is 'c' i.e., GABA transaminase inhibitor Vigabatrin (g vinyl GABA)* It is a newer anti - convulsant which is an inhibitor of enzyme GABA transaminase; it thus increases GABA concentration at synapse.* It is mainly used in patients with refractory epilepsy visual field defects and behavioural changes restricts its use.