This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Bleeding from the GUT and diseases of esophagus, Subject name: Medicine
Diffuse oesophageal spasm treatment is? 
Select and explain. 
A. Pneumatic dilatation, B. Oxybutynin, C. Nitrates, D. Botulinum toxin and pneumatic dilation
C: Nitrates
Answer: C: Nitrates 
Explanation: Choice D is closely worded and is used primarily in the treatment of achalasia. Diffuse oesophageal spasm is managed by the following interventions: Nitrates and CCB Hydralazine Botulinum toxin Anxiolytics Long myotomy or esophagectomy for severe weight loss or unbearable in Diffuse oesophageal spasm Nutracker oesophagus Hypeensive LES Simultaneous non peristaltic contractions ( >20% of wet swallows ) Mean peristaltic amplitude of > 180 mm Hg for increased duration of contraction >7 seconds normal peristaltic sequence Elevated LES pressure > 26 mmHg normal LES relaxation Normal oesophageal peristalsis