This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
The current practice guideline for the management of hereditary spherocytosis, EXCEPT: 
Select and explain. 
A. Avoid splenectomy in mild cases, B. Delay splenectomy upto 4 years, C. Antipneumococcal vaccination before splenectomy, D. Penicillin prophylaxis post splenectomy
D: Penicillin prophylaxis post splenectomy
Answer: D: Penicillin prophylaxis post splenectomy 
Explanation: Current guidelines for the management of hereditary spherocytosis: Avoid splenectomy in mild cases. Delay splenectomy upto 4 years of age Antipneumococcal vaccination before splenectomy Splenectomy may be combined with cholecystectomy if indicated Penicillin prophylaxis postsplenectomy is controversial. Ref: Harrison, E-18,P-876.