This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Neuromuscular Blocker, Subject name: Anaesthesia
All of the following nondepolarising neuromuscular blocker causes histamine release except- 
Select and explain. 
A. Atracurium, B. Mivacurium, C. d-tubocurare, D. Vecuronium
D: Vecuronium
Answer: D: Vecuronium 
Explanation: All benzylisoquinoline nondepolarising neuromuscular blocker causes histamine release. Aminosteroid group does not release histamine. NDNB divided in three group according to duration of action - Long- acting, intermediate - acting and sho- acting. Aminosteroid Long acting Pancuronium pipecuronium Benzylisoquinoline D-tubocurane, Doxacurium Intermediate acting Aminosteroid Vecuronium Rocuronium Benzylisoquinoline Atracurium Cisatracurium Sho acting Aminosteroid Rapacuronium Benzylisoquinoline Mivavcurium * Benzylisoquinoline group causes histamine release so IV injection of these drugs can cause hypotension,tachycardia, Bronchospasm, Flushing.