This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pediatrics
Most common brain lesion causing central precocious puberty is: 
Select and explain. 
A. Tuberculous meningitis, B. Tuberous sclerosis, C. Astrocytoma, D. Hypothalamic hamartoma
D: Hypothalamic hamartoma
Answer: D: Hypothalamic hamartoma 
Explanation: d. Hypothalamic hamartoma(Ref: Nelson's 20/e p 2658-2659)Hypothalamic hamartomas are the most common brain lesion causing central precocious puberty.