This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Neurodegenerative Disorder, Subject name: Pathology
Nucleus involved in Alzheimer's disease is: 
Select and explain. 
A. Nucleus Basalis of Meyne, B. Superior salivary nucleus, C. Ventromedial nucleus of thalamus, D. All of the above
A: Nucleus Basalis of Meyne
Answer: A: Nucleus Basalis of Meyne 
Explanation: The brain of Alzheimer's disease patients shows severe neuronal loss in the nucleus basalis of Meyne. This pa is the major source of cholinergic input to cerebral cortex.