This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Sources of blood glucose, Subject name: Biochemistry
Major source of Acetyl CoA: 
Select and explain. 
A. Triglycerides, B. Fatty acids, C. Pyruvate, D. Alanine
C: Pyruvate
Answer: C: Pyruvate 
Explanation: As nothing is mentioned we have to assume question is asking about fed-state. In fed-state, major source of fuel is carbohydrates followed by fats and proteins. Acetyl CoA is derived from Carbohydrates, Fats & Proteins also. So in fed state major source will be Carbohydrates. Glucose forms pyruvate & then it forms Acetyl CoA. So best answer here is Pyruvate.