This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Psychiatry
Neurotransmitter which is found in increased qualities in mania is: 
Select and explain. 
A. Noradrenaline, B. Serotonin, C. Acetyl choline, D. GABA
A: Noradrenaline
Answer: A: Noradrenaline 
Explanation: According to norepinephrine hypothesis of affective illness, the bipolar disorder is related with the availability of norepinephrine at synaptic sites. Norepinephrine is less available in synapses in depressive patients but it is abundant in maniac patients. Hypothyroidism is very common in patients with bipolar disorder. Ref: Loosen P.T., Shelton R.C. (2008). Chapter 18. Mood Disorders. In M.H. Ebe, P.T. Loosen, B. Nurcombe, J.F. Leckman (Eds), CURRENT Diagnosis & Treatment: Psychiatry, 2e.