This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti Microbial, Subject name: Pharmacology
Ethambutol is avoided in children as it causes - 
Select and explain. 
A. Dental maldevelopment, B. Visual disturbance, C. Renal failure, D. Growth retardation
B: Visual disturbance
Answer: B: Visual disturbance 
Explanation: Ans. is 'b' i.e., Visual disturbanceo The main adverse effect of Ethambutol is retrobulbar optic neuritis (unilateral or B/L).o This causes loss of visual activity, red-green colour blindness, central scotoma, peripheral vision loss.o The changes reverse, if the t/t is stopped promptly if not, the patient may go blind.o Children below 6 years of age are not given ethambutol because children are unable to report early visual deterioration.o Ethambutol also produces hyperuricemia.