This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
A female with 45X0 genotype has primary amenorrhoea. Most likely diagnosis is: 
Select and explain. 
A. Gonadal Dysgenesis, B. Androgen Insensitivity syndrome, C. Meyer Rokitansky Kuster Houser Syndrome., D. Congenital adrenal Hyperplasia
A: Gonadal Dysgenesis
Answer: A: Gonadal Dysgenesis 
Explanation: The genotype XO belongs to the Turner's syndrome which is characteristic of gonadal dysgenesis, sho stature and external and internal dysmorphic features. The gonadal dysgenesis leads to primary amenorrhea. Ref: Clinical Obstetrics and Gynaecology by Brian A. Magowan, Philip Owen, James Drife, Pages 52-53 Disorders of Sex Development By John M. Hutson, Garry L. Warne, Sonia Grover, Page 91.