This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nose and PNS, Subject name: ENT
An 18-year-old girl presented with multiple nasal polypi in both nostrils with nasal obstruction and sinusitis. CT scan shows dense shadows in the sinuses. Histopathology did not show fungal invasion of tissues. All of the following treatments can be given except: 
Select and explain. 
A. Amphotericin B, B. Intranasal corticosteroids, C. Surgical removal, D. Anti-histaminic
A: Amphotericin B
Answer: A: Amphotericin B 
Explanation: The clinical picture and CT findings in the above patient indicate a diagnosis of allergic fungal rhinosinusitis. It is a type I hypersensitivity presenting with nasal polypi. CT findings are hyperdense material in the sinus cavity. Histologically no tissue invasion by fungus is seen though fungus can be stained and cultured from the tissues. Since tissue invasion by fungus is absent, there is no need for amphotericin B, though all other modes of treatment would be required to treat nasal polypi and type I hypersensitivity reaction.