This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Stomach and Intestines, Subject name: Pediatrics
A male infant presented with distension of abdomen shortly after birth with passing of less meconium. Subsequently a full-thickness biopsy of the rectum was performed. The rectal biopsy is likely to show: 
Select and explain. 
A. Fibrosis of submucosa, B. Lack of ganglion cells, C. Thickened muscularis propria, D. Hyalinization of the muscular coat
B: Lack of ganglion cells
Answer: B: Lack of ganglion cells 
Explanation: b. Lack of ganglion cells(Ref: Nelson's 20/e p 1894-1897, Ghai 8/e p 285-286)"Whenever neonate presents with delayed passage of stool, Hirschsprung's disease should be suspected".