This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pathology
All are good prognostic factors for neuroblastoma except 
Select and explain. 
A. Trk-A expression absent, B. Absence of 1 p loss, C. Absence of 17 p gain, D. Absence of 11 q loss
A: Trk-A expression absent
Answer: A: Trk-A expression absent 
Explanation: The expression of specific neurotrophin receptors like TrkA are good prognostic factors for Neuroblastoma whereas expression of TrkB like neurotrophin receptors worsens the disease. Refer robbins 9/e 260p