This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Excretory System (Kidney, Bladder) Acid-Base Balance, Subject name: Physiology
In the presence of ADH, greatest fraction of the filtered water is reabsorbed from: 
Select and explain. 
A. PCT, B. Loop of Henle, C. DCT, D. Collecting duct
A: PCT
Answer: A: PCT 
Explanation: 65%-70% of the filtered water is reabsorbed from the PCT. This is called obligatory water reabsorption and occurs irrespective of the osmolarity of ECF. In the complete absence of ADH action, 88% of the filtered water is reabsorbed from various segments of nephron. 10%-12% water is reabsorbed from collecting duct under the maximum action of ADH. This is called facultative water reabsorption. Water reabsorption from the collecting duct is determined by osmolarity of ECF.