This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Cytochrome C in apoptosis acts by 
Select and explain. 
A. IL 10, B. Bcl-2, C. FADD, D. Apaf 1
D: Apaf 1
Answer: D: Apaf 1 
Explanation: After releasing of cytochrome in cytosol, they binas to Apart 1 protein which leads to formation of a complex apoptosome. This complex binds to caspase-9 which is a critical initiator caspase of the mitochondrial pathway of apoptosis.
Also Know
Most critical organ for apoptosis = Mitochondrion
Most characteristic feature of apoptosis = Chromatin condensation
Marker for apoptosis = Annexin V
Molecular marker for apoptosis = CD 95