This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy, Subject name: Pharmacology
A patient on treatment for leukemia develoPS chest pain pulmonary infiltrates and pleural effusion. The likely cause is 
Select and explain. 
A. Daunorubicin, B. Hydroxyurea, C. Cytarabine, D. Tretinoin
D: Tretinoin
Answer: D: Tretinoin 
Explanation: Refer Katzung 10th,/899 Tretinoin causes chest pain, pleuritis, pulmonary infiltrates and pleural effusion. It is known human teratogen Daunorubicin and Doxorubicin cause cardiotoxicity manifested as arrhythmias and CHF