This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Medicine
Which of the following best describes sensitization to a drug? 
Select and explain. 
A. an allergic response, B. a purely behavioral effect, C. a shift to the right of a dose response curve, D. reverse tolerance
D: reverse tolerance
Answer: D: reverse tolerance 
Explanation: Sensitization is the reverse of tolerance. It refers to an increase in effect of the drug with repetition of the same dose. It does not occur during an acute binge. The dose response curve would be shifted to the left.