This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Disorder of Pigmentation, Subject name: Skin
Enzyme deficient in occulocutaneous albinism type 1 is - 
Select and explain. 
A. Tyrosinase, B. Pink protein, C. Tyrosinase related protein 1, D. Membrane associated transport protein (MATP)
A: Tyrosinase
Answer: A: Tyrosinase 
Explanation: Ans. is 'a' i.e., Tyrosinase Characteristics of AlbinismDiseaseChromosomeGene locusProtein {Biogenesis of lysome-related Organelles complex (BLOC)]Distinguishing signsOculocutaneous albinism type 11 lq21TYRTyrosinase/TYRType lA-no pigment Type 1 B-some pigmentOculocutaneous albinism type 215q11 2-q12PPink protein/PSome pigmentation apparent: nevi and freckles possibleOculocutaneous albinism type 39p23TYPR1Tyrosinase-related protein 1/TYRP1Similar to OCAZ phenotype includes rufous (red) albinism phenotypeOculocutaneous albinism type 45pMATPMembrane-associated transporter protein/MATPSimilar to OCAZ phenotype most common in individuals with Asian biogeographic ancestry.Chediak-Higashisyndromelq43LYSTLysosome trafficking/LYSTGiant peroxidase-positive lysosomal granules in neutrophils