This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Blood, Subject name: Medicine
Best treatment for massive pulmonary embolism: 
Select and explain. 
A. Intravenous tissue plasminogen activator, B. Heparin, C. Pulmonary thrombo-embolectomy, D. Low molecular weight heparin + warfarin
A: Intravenous tissue plasminogen activator
Answer: A: Intravenous tissue plasminogen activator 
Explanation: Ans. A. Intravenous tissue plasminogen activator* Massive pulmonary embolism is best managed by thrombolysis using tissue plasminogen activator.* In case thrombolysis is contraindicated then in these patient fogarty catheter removal of clot in pulmonary artery would be done.* In submassive pulmonary embolism heparin is used. Chronic pulmonary embolism leading to pulmonary- hypertension (known as chronic thromboembolic hypertension) is treated with a surgical Procedure known as a pulmonary thromboendarterectomy