This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Physiology
At what stage of erythropoiesis does Hemoglobin appear? 
Select and explain. 
A. Reticulocyte, B. Intermediate normobalst, C. Early normoblast, D. Erythroblast
B: Intermediate normobalst
Answer: B: Intermediate normobalst 
Explanation: a pronormoblast, also commonly called an proerythroblast or a rubriblast. This becomes a basophilic or early normoblast, also commonly called an erythroblast, then. a polychromatophilic or intermediate normoblast, then. an ohochromatic or late normoblast. At this stage the nucleus is expelled before the cell becomes. Ref: guyton and hall textbook of medical physiology 12 edition page number: 111,112,113