This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: FMGE 2017, Subject name: Medicine
Which of the following is the best investigation for acute gout? 
Select and explain. 
A. Serum uric acid, B. Uric acid in synol fluid, C. Uric acid in urine, D. Anti CCP antibodies
B: Uric acid in synol fluid
Answer: B: Uric acid in synol fluid 
Explanation: in Acute gout there is increase in value of uric acid but when acute gout attack sta, uric acid is not elevated in blood, but elevated in synol fluid. Acute gout- uric acid in synol fluid. Chronic Gout - S. Uric acid. Acute gout condition has crystallization of uric acid in the joint space IOC - uric acid in synol fluid (Joint Aspiration) These crystals exhibiting -vet birefringence in polarized light.