This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
DNA repair defect is associated 
Select and explain. 
A. Xeroderma pigmentosum, B. Icthyosis, C. Angelman syndrome, D. DiGeorge's syndrome
A: Xeroderma pigmentosum
Answer: A: Xeroderma pigmentosum 
Explanation: Robbins basic pathology 9th edition page no 197, The basis of this disorder is DNA repair such dna damage is prevented by nucleotide excision repair system, and an inherited loss of any one of these can give rise to xeroderma pigmentosum