This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
Which component of Strep. Pyogenes has cross reactivity to Synovium of Human tissues? 
Select and explain. 
A. Capsular Hyaluronic Acid, B. Cell wall protein, C. Group A carbohydrate Antigen, D. Peptidoglycan
A: Capsular Hyaluronic Acid
Answer: A: Capsular Hyaluronic Acid 
Explanation: Capsular Hyaluronic acid from streptococcus pyogenes always cross-reacts with human synol fluid and not with cell wall protein, group A carbohydrate antigen and peptidoglycan. Ref: Textbook of Microbiology By Ananthanarayan, 7th Edition, Pages 205, 207; Lippincott's Illustrated Reviews: Pharmacology, 2nd Edition, Pages 80, 81