This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Secondaries are common in a/e - 
Select and explain. 
A. Skull, B. Hand & feet bones, C. Proximal limb bones, D. Pelvic
B: Hand & feet bones
Answer: B: Hand & feet bones 
Explanation: Metastasis may occur in any bone but most commonly involve axial skeleton (e.g. vertebra, pelvis, ribs. skull, sternum) Proximal femur, and humerus in descending order.
Red marrow in these areas are rich in capillary network, slow blood flow and nutrient environment facilitates the implantation and growth of the tumour cells.
Metastasis in small bone of hand and feet are uncommon.
Metastatic tumors are the most common form of skeletal malignancy.