This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunology, Subject name: Microbiology
Genetic deficiency of complement factor causes: 
Select and explain. 
A. Hereditary angioneurotic edema, B. SLE- an autoimmune disease, C. Pyogenic bacterial infections, D. All of the above
D: All of the above
Answer: D: All of the above 
Explanation: Ans: d (All of the above) Ref: Ananthanaraya 7th ed, p. 115Deficiency of complement components are associated with a variety of syndromesDeficiencySyndromeCl inhibitorHereditary angoneurotic edema (main mediator of edema is C2 kinin released)C1C2C4SLE & collagen vascular disordersC3 & C3b inactivatorRecurrent pyogenic infectionsC5-8Gram - ve bacteremiaC9No particular diseaseRemember: Treatment of hereditary angioneurotic oedema is infusion of FFP