This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
Karyopyknotic index is a method for ? 
Select and explain. 
A. Ovarian carcinoma, B. Hormonal evaluation, C. Dysplasia measurement, D. Measurement of cells in active replication
B: Hormonal evaluation
Answer: B: Hormonal evaluation 
Explanation: It is the percentage of tooth royal cells having karyopyknotic nucleus exfoliate a from the vagina... Which gives an idea about the hormonal status of the patient. Karyopyknosisis the irreversible condensation of the chromatin in the nucleus of a cell undergoing apoptosis or necrosis.