This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Psychiatry
Most impoant receptors involved with schizophrenia are? 
Select and explain. 
A. GABAA, B. GABA,,, C. DZd, D. 5-HT
C: DZd
Answer: C: DZd 
Explanation: Ans. C. DZdDopamine hypothesis is the most accepted hypothesis for schizophrenia. There is hyperactivity of dopaminergic system. This hypothesis is suppoed by :Amphetamine and cocaine which release dopamine in central synapses induce schizophrenia like symptoms; andAntipsychotic drugs control the schizophrenic symptoms by blocking dopamine (D2) receptors.