This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cell Wall Synthesis Inhibitors, Subject name: Pharmacology
All of the following statements regarding development of resistance against penicillins is true EXCEPT? 
Select and explain. 
A. Bacteria may develop inactivating enzymes called penicillinases., B. Bacteria may develop altered penicillin binding proteins, C. Bacteria may develop alternate metabolic pathway, D. Bacteria may become less permeable to penicillins
C: Bacteria may develop alternate metabolic pathway
Answer: C: Bacteria may develop alternate metabolic pathway 
Explanation: Major methods of development of resistance to penicillins are: Development of beta lactamases like penicillinases e.g. many staphylococci Development of altered PBPs e.g. in MRSA Decreased permeability to penicillins e.g. in low level resistance to gonococci