This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endometrial Carcinoma and Hysterectomy, Subject name: Gynaecology & Obstetrics
Effect of tamoxifen:- 
Select and explain. 
A. Increased risk of endometrial carcinoma, B. Decreased risk of ovarian CA, C. Causes cardiotoxicity, D. Increased risk of osteoporosis
A: Increased risk of endometrial carcinoma
Answer: A: Increased risk of endometrial carcinoma 
Explanation: Effects of tamoxifen Tamoxifen is an S.E.R.M (selective estrogen receptor modulator) Increase risk of endometrial cancer Decrease risk of osteoporosis Useful in breast cancer Menopausal symptoms like hot flushes