This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Increased susceptibility to breast cancer is likely to be associated with a mutation in the following gene -a) P53 b) BRCA-1 c) Retinoblastoma (Rb)  d)  H-Ras 
Select and explain. 
A. ab, B. bc, C. ad, D. bd
A: ab
Answer: A: ab 
Explanation: None