This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
During gluconeogensis reducing equivalents from mitochondria to cytosol are transpoed by 
Select and explain. 
A. Malate, B. Aspaate, C. Glutamate, D. Oxaloacetate
A: Malate
Answer: A: Malate 
Explanation: A i.e. MalateMallate shuttle is a system by which reducing equivalents (NADH) produced in glycolysisQ are transferred from cytosol to mitochondria to yield energy.NADH produced in the glycolysisQ, is extramitochondrial where as the electron transpo chain, where NADH has to be oxidized to NAD+ is in the mitochondria (Oxidation of 1 NADH yields 3 ATP/2.5 ATP). NADH is impermeable to mitochondrial membrane, so to enable transfer of NADH inside mitochondria Shuttle system is utilized.