This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology and breast, Subject name: Anatomy
Young female presents with hypeension with VMA >14 mg/day, associated with -a) Medullary Ca Thyroidb) Von Hippel Lindau diseasec) Sturge weber syndromed) Grave's diseasee) Neurofibromatosis 
Select and explain. 
A. bcd, B. abc, C. acde, D. abce
D: abce
Answer: D: abce 
Explanation: Biochemical tests for pheochromocytoma Most sensitive screening test : Urinary catecholamines and VMA levels Best diagnostic test : Fractionated plasma metanephrines Pharmacological tests Positive response to phentolamine is reduction of BP of atleast 35/25 mmHg after 2 min. It is not a diagnostic and biochemical confirmation Glucagon infusion increases catecholamines release and causes paroxysm of hypeension She is suspected of having pheochromocytoma Syndromes associated with pheochromocytoma (MVVS) MEN-2A & MEN-2B VHL syndrome Von-Recklinghausen syndrome Struge-weber syndrome Ref: schwaz's principle of surgery 10th edition Pgno :1586