This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Bacteriology, Subject name: Microbiology
Skin lesion in meningococcal meningitidis is due to 
Select and explain. 
A. Exotoxin, B. Endotoxin, C. Allergic reaction, D. Direct vascular Damage
B: Endotoxin
Answer: B: Endotoxin 
Explanation: The endotoxin lipopolysaccharide of Meningococci is released by autolysis.- vascular endothelium is paicularly sensitive to the endotoxin. All major inflammatory cascade systems, as well as cytokines and nitric oxide, are triggered and unregulated. Reference: Textbook of Microbiology; Anathanarayan and panicker's; 10th edition; Page no: 232