This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General physiology, Subject name: Physiology
What propey of the postsynaptic neuron would optimize the effectiveness of two closely spaced axodendritic synapses? 
Select and explain. 
A. A high membrane resistance, B. A high dendritic cytoplasmic resistance, C. A small cross-sectional area, D. A small space constant
A: A high membrane resistance
Answer: A: A high membrane resistance 
Explanation: Space constant increases with increasing membrane resistance or decreasing cytoplasmic resistance.Cytoplasmic resistance decreases as the cross-sectional area increases.Ref: Guyton; 13th edition; Chapter 46 Organization of the Nervous System, Basic Functions of Synapses, and Neurotransmitters