This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney disorders, Subject name: Pathology
All are true about nephronophthisis except: 
Select and explain. 
A. Interstitial fibrosis, B. Coical tubular hyperophy, C. Cysts in the medulla, D. 20% cases are non-familial
B: Coical tubular hyperophy
Answer: B: Coical tubular hyperophy 
Explanation: 2 types of cystic disease affecting the renal medulla are : 1. Medullary sponge kidney Relatively common Usually innocuous condition Associated with nephrolithiasis 2.Nephronophthisis- Medullary cystic disease complex Associated with renal dysfunction. Cause of chronic kidney disease that usually begins in childhood. Coical tubulointerstitial damage and not hyperophy occurs in nephronophthisis.