This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: DNB 2018, Subject name: Pharmacology
Analgesic effect of paracetamol is mediated by action on which of the following receptor? 
Select and explain. 
A. NK 1, B. BK 1, C. Px23, D. TRPV 1
D: TRPV 1
Answer: D: TRPV 1 
Explanation: PCM uses - Fever Pain Not for inflammation Peroxide:- Presence of peroxide at inflammation site inactivate PCM. COX3 inhibitor :- Presence of COX3 in brain, therefore fever and pain can be treated with PCM. Vanilloid receptor:-Metabolites of PCM binds with vanilloid receptor to produce analgesia. Transient Receptor Potential vanilloid 1:TRPV 1