This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
Amyloidosis mostly affects 
Select and explain. 
A. Liver, B. Tounge, C. Colon, D. Hea
D: Hea
Answer: D: Hea 
Explanation: Hea. Amyloidosis of the hea may occur either as iso- lated organ involvement or as pa of a systemic distribution. When accompanied by systemic involvement, it is usually of the AL form. The isolated form (senile amyloidosis) usually is confined to older persons. The deposits may not be evident on gross examination, or they may cause minimal to moder- ate cardiac enlargement. The most characteristic gross find- ings are gray-pink, dewdrop-like subendocardial elevations, paicularly evident in the atrial chambers. On histologic examination, deposits typically are found throughout the myocardium, beginning between myocardial fibers and eventually causing their pressure atrophy Ref Robbins 9/e pg 157