This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Congenital CNS malformations, Subject name: Pediatrics
Neural tube defects have which one of the following inheritance patterns? 
Select and explain. 
A. Autosomal dominant, B. Autosomal recessive, C. X-linked recessive, D. Multifactorial
D: Multifactorial
Answer: D: Multifactorial 
Explanation: - Neural tube defects: Occurs d/t failure of proper closure of neural tube Show multifactorial inheritance. Examples: 1. Meningocele 2. Meningomyelocele 3. Anencephaly 4. Spina bifida occulta 5. Iniencephaly 6. Encephalocele - Extra Edge: Other conditions having multifactorial inheritance are Hypeension Diabetes mellitus Most of the congenital hea diseases etc