This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: JIPMER 2017, Subject name: Ophthalmology
Pathology in keratomalacia: 
Select and explain. 
A. Accumulation of desquamated debris, B. Absence of mucus, C. Breakdown of collagen fibers in corneal stroma, D. Infection with corynebacterium xerosis
C: Breakdown of collagen fibers in corneal stroma
Answer: C: Breakdown of collagen fibers in corneal stroma 
Explanation: Breakdown of collagen fibres in corneal stroma occur in keratomalacia. VitA deficiency leads to keratomalacia in which cornea becomes dull and insensitive, hazy and yellow infiltrates form until finally the whole tissue undergoes necrosis and seems to melt away (keratomalacia) within a few hours. A characteristic feature is the absence of inflammatory reaction.