This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Diarrhea (loose stools) is a side effect of: 
Select and explain. 
A. Omeprazole, B. Sucralfate, C. Metoclopramide, D. Misoprostol
D: Misoprostol
Answer: D: Misoprostol 
Explanation: Misoprostol is a prostaglandin analogue which inhibits acid secretion. The primary indication is the prevention and treatment of NSAID associated gastrointestinal injury and blood loss. Major problems in the use of misoprostol are diarrhea, abdominal cramps, uterine bleeding, abortion and the need for multiple doses.