This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Carcinoma Cervix, Subject name: Gynaecology & Obstetrics
A 40-year-old woman presents with abnormal cervical cytology on PAP smear suggestive of CIN (III). The next best step in management is: 
Select and explain. 
A. Hysterectomy, B. Colposcopy and LEEP, C. Colposcopy and cryotherapy, D. Conization
B: Colposcopy and LEEP
Answer: B: Colposcopy and LEEP 
Explanation: Ans. is b, i.e. Colposcopy and LEEP.The patient in the question has CIN (III) on pap smear. PAP smear is only a screening procedure and not diagnostic. Hence for confirming the diagnosis, we will have to do colposcopy followed by LEEP to treat it, if it is confirmed. This can be done in 2 steps or single step.