This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Psoriasis, Subject name: Dental
Which of the following biologic agent approved for treatment of psoriasis or psoriatic ahritis is not anti-TNF-a? 
Select and explain. 
A. Etanercept, B. Alefacept, C. Infliximab, D. Adalimumab
B: Alefacept
Answer: B: Alefacept 
Explanation: BIOLOGICS APPROVED FOR PSORIASIS(Ps) OR PSORIATIC AHRITIS(PsA) Anti TNF- a Etanercept Adalimumab Infliximab Alefacept -Anti-CD-2 (fusion protein against LFA-3) Other TNF alpha inhibitors -ACE In Goli:A- AdalimumabC- CeolizumabE- EtanerceptIn- InfliximabGoli- Golimumab"