This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy, Subject name: Pharmacology
The antimicrobial agent which inhibits the ergosterol biosynthesis is 
Select and explain. 
A. Ketaconazole, B. Amphotercin B, C. 5-flucytosine, D. Grisefulvin
A: Ketaconazole
Answer: A: Ketaconazole 
Explanation: Refer KDT 6/e 761 Azoles act by inhibiting an enzyme, lanosterol -14-alpha -demethylase. This enzyme is involved in formation of ergosterol Amphotercin B acts6by binding to ergosterol and forming pores in fungal cell membrane