This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Respiratory System, Subject name: Physiology
Over-inflation of lung is prevented by? 
Select and explain. 
A. Chemo-receptor, B. Hering-Breuer reflex, C. Surfactant, D. Clara cells
B: Hering-Breuer reflex
Answer: B: Hering-Breuer reflex 
Explanation: Ans. B Hering Breur ReflexRef: Gattong, 25th ed. pg. 662* Hering- Breuer reflex is reflex triggered to prevent over inflation of lung.* Smooth muscles of lung have pulmonary stretch receptors which respond to excessive stretching of lung during large inspirations.* The reflex limits the tidal volume while increasing the respiratory frequency* Hering Breur inflation reflex is increase in duration of expiration produced by steady lung inflation.* Hering breur deflation reflex is a decrease in duration of expiration produced by steady lung deflation.* Surfactant prevents collapse of the lung.