This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of carbohydrate, Subject name: Biochemistry
Biosynthesis of glucuronic acid requires the 
Select and explain. 
A. Oxidation of UDP glucose, B. Oxidation of glucose 6-phosphate, C. Oxidation of 6-phophoguconate, D. Oxidanation of glucose
A: Oxidation of UDP glucose
Answer: A: Oxidation of UDP glucose 
Explanation: Glucuronic acid is a sugar acid derived from glucose, with its sixth carbon atom oxidized to a carboxylic acid. In living beings, this primary oxidation occurs with UDP-a-D-glucose (UDPG), not with the free sugar.Ref: DM Vasudevan, 7th edition, page no: 120