This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetics, Subject name: Pathology
In an Autosomal Dominant disorder, mother is affected but is heterozygous. Father is normal. What are the chance of disease in children? 
Select and explain. 
A. 50% affected, B. 25% affected, C. 75% affected, D. All affected
A: 50% affected
Answer: A: 50% affected 
Explanation: Ans. (a) 50% affected(Ref: Robbins 9th/pg 140; 8th/pg 140)In an Autosomal Dominant disorder, mother is affected but is heterozygous and father is normal.Therefore, the chances of disease in children is 50%