This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hemolytic anemia, Subject name: Pathology
Howel-Jolly bodies may be seen after - 
Select and explain. 
A. Hepatectomy, B. Splenectomy, C. Pancreatectomy, D. Cholecystectomy
B: Splenectomy
Answer: B: Splenectomy 
Explanation: Ans. is 'b' i.e., Splenectomy Chronic Manifestations of splenectomy include :Marked variation in size and shape of erythrocytes - anisocytosis / poikilocytesHowell - Jolly bodies : nuclear remnantsHeinz bodies : denatured haemoglobingBasophillic stipplingOccasional nucleated erythrocyte in peripheral bloodHowell-Jolly bodies are smooth round remnants of nuclear chromatin seen in erythrocytes in conditions like :o Megaloblastic anemia o After Splenectomy o Hemolytic anemia