This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Urinary Tract, Subject name: Pediatrics
The most common type of idiopathic nephrotic syndrome seen in children is: 
Select and explain. 
A. Focal segmental glomerulosclerosis, B. Minimal change disease, C. Membranous nephropathy, D. Membranoproliferative glomerulonephritis
B: Minimal change disease
Answer: B: Minimal change disease 
Explanation: Ans. B. Minimal change diseaseNephrotic syndrome is a common renal disorder in children characterized by massive proteinuria, hypoalbuminemia and periorbital puffiness. The majority of children with nephrotic syndrome have minimal change disease (minimal glomerular changes seen histologically). Focal segmental glomerulosclerosis, membranous glomerulonephritis, membranous nephropathy and diffuse mesangial proliferative glomerulonephritis are other subtypes of nephritic syndrome, each with distinct histological changes in the glomerular biopsy examination.