This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Epilepsy, Subject name: Pharmacology
Perampanel is 
Select and explain. 
A. NMDA antagonist, B. AMPA antagonist, C. GABA mimetic, D. Calcium channel inhibition
B: AMPA antagonist
Answer: B: AMPA antagonist 
Explanation: Perampanel is recently approved selective non-competitive antagonist of AMPA receptorwhich is used as add on therapy for paial seizure. Adverse effect of this drug is somnolence, weight gain Felbamate is NMDA inhibitor Barbiturates are GABA mimetic Ethosuximide , valproate inhibit the calcium channels.