This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti Histaminics, Subject name: Pharmacology
Which of the following is not a 2nd generation antihistamine? 
Select and explain. 
A. Cetrizine, B. Cyclizine, C. Loratidine, D. Fexofenadine
B: Cyclizine
Answer: B: Cyclizine 
Explanation: Ans. b. Cyclizine (Ref: Katzung 11/e p277)Cyclizine is a first generation antihistaminics.Cetrizine, Loratidine and Fexofenadine are second generation antihistaminics.AntihistaminicsFirst GenerationSecond Generation* Ethanolamines:* Piperadine:- FexofenadineQ* Miscellaneous:- LoratidineQ- CetrizineQ- Carbinoxamine- Diphenhydramine* Piperazine:- Dimenhydrinate- Hydroxyzine- Meclizine* Alkyiamines:- CyclizineQ- Bromopheniramine* Phenothiazines:- Promethazine* Miscellaneous:- Cyproheptadine- Chlorpheniramine