This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Pharmacotherapy in psychiatry, Subject name: Psychiatry
Side effect of SSRI 
Select and explain. 
A. Nausea, B. Diarrhoea, C. Weight gain, D. Rash
C: Weight gain
Answer: C: Weight gain 
Explanation: SIDE EFFECTS Paradoxical SUICIDE, this is a type of suicide where an antidepressant used to treat depression and decrease suicide increase the chance of suicidal attempt ( IT'S A PARADOX). The explanation that is given is SSRI initially activates the patient and decreases fatigue, thus patients with low mood and suicidal ideas will have more energy to act on the ideas. GIT- loose stools and ulcer thus it should not be given in an empty stomach SD- delays ejaculation. This mechanism is used for its prescription in patients with premature ejaculation ANXIETY WEIGHT GAIN INSOMNIA Ref.Kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 1013