This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
Staphalococcus Oxacillin resistance is best detected by? 
Select and explain. 
A. Cefotixin MIC, B. Cefotixin disc diffusion, C. Oxacillin disc diffusion, D. Oxacillin agar
B: Cefotixin disc diffusion
Answer: B: Cefotixin disc diffusion 
Explanation: Ans. is 'b' i.e., Cefotixin disc diffusionOxacillin (also methicillin) resistance is detected by finding the presence of mec A gene."Cefoxitin disc diffusion has been repoed to more occurately predict mec A gene presence than oxacillin disc diffusion."The use of cefoxitin MIC test has not been recommended by the CLSI-AST (Clinical and Laboratory Standards Institute), but its presence is equivalent to cefoxitin disc diffusion.