This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Psychiatry
All of the following are associated with better prognosis in schizophrenia, EXCEPT: 
Select and explain. 
A. Married, B. Late onset, C. Acute onset, D. Negative symptoms
D: Negative symptoms
Answer: D: Negative symptoms 
Explanation: Late , acute onset of symptoms and married status all are associated with good prognosis in schizophrenia.Factors associated with good prognosis in schizophrenia are married, acute onset , positive symptoms, late onset of disease, presence of good suppo systems, mood disorder symptoms, obvious precipitating factors, family history of mood disorders, good premorbid social, sexual and work histories.Ref: Kaplan and Sadock's Study Guide and Self-Examination Review in Psychiatry By Benjamin J. Sadock, page 135.