This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Pharmacotherapy in psychiatry, Subject name: Anatomy
mood stabilizer used in the management of depression 
Select and explain. 
A. lamotrigine, B. valproate, C. carbamezepine, D. lithium
A: lamotrigine
Answer: A: lamotrigine 
Explanation: Lamotrigine is a mood stabilizer which works best in BIPOLAR DEPRESSION Lithium is a mood stabilizer which works best in BIPOLAR MANIA valproate is a mood stabilizer which works best in RAPID CYCLING Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, 935