This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Predictable and dose related drug induced hepatic injury is seen with all, EXCEPT: 
Select and explain. 
A. Carbon tetrachloride, B. Acetaminophen, C. INH, D. Oral contraceptive agent
C: INH
Answer: C: INH 
Explanation: There are two major types of chemical hepatotoxicity Direct toxicity-Predictable with sho latent period Idiosyncratic-Not predictable and it can happen at any time Examples of direct hepatotoxic effects Carbon tetrachloride Acetaminophen OCP INH causes idiosyncratic type reaction Hepatitis is infrequent and unpredictable Ref: Harrison, Edition-18, Page-2558