This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Central Nervous system, Subject name: Pharmacology
Which of the following antiepileptic agent does not act Na+ channel modulation? 
Select and explain. 
A. Vigabatrin, B. Phenytoin, C. Valproate, D. Lamotrigne
A: Vigabatrin
Answer: A: Vigabatrin 
Explanation: it is an inhibitor of GABAtransaminase, the enzyme which degrades GABA. Anticonvulsant action may be due to increase in synaptic GABA concentration REF KD TRIPATHI 8TH ED.