This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Systemic Bacteriology (Gram Positive Bacilli, Gram Negative Bacilli), Subject name: Microbiology
True for Vi polysaccharide vaccine 
Select and explain. 
A. Local side effects are common, B. Severe systemic side effect, C. Contra indicated in HIV, D. Can be given with other vaccines like Hepatitis B & Yellow fever
D: Can be given with other vaccines like Hepatitis B & Yellow fever
Answer: D: Can be given with other vaccines like Hepatitis B & Yellow fever 
Explanation: Vi polysaccharide vaccine can be given with other vaccines like Hepatitis B & Yellow fever. Option 1, 2, 3, 4 -Typhim Vi is a subunit vaccine containing the cell surface Vi polysaccharide extracted from Salmonella enterica serovar Typhi, S. typhi Ty2 strain. -Typhim Vi vaccine is indicated for active immunization against typhoid fever for persons two years of age or older. -The antibody response may be inadequate in children under 2 years of age. - Dose for adults and children is a single injection of 0.5 mL given intramuscularly in the deltoid. - Reimmunization every two years under conditions of repeated or continued exposure to the S typhi organism is recommended at this time. - Typhim Vi vaccine has efficacy against typhoid fever caused by S.typhi infection only. =The adverse reactions are predominately minor and transient local reactions:- -Local reactions such as injection site pain, erythema and induration almost always resolve within 48 hours of vaccination. -Though the antibody response in immunodeficiency states are often suboptimal, it should be given in HIV patients. -TYPHIm Vi may be administered during the same vaccination session with other common vaccines (yellow fever, diphtheria, tetanus, poliomyelitis, rabies prepared on Vero cells, meningitis A+C, hepatitis A and hepatitis B.) -Other vaccines for prophylaxis against enteric fever are:- Mono/di/trivalent heat- killed phenol preserved parenteral vaccines. Live attenuated Typhoid vaccine.