This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunology and Rheumatology, Subject name: Medicine
Patient present with severe headache with the following sign. Diagnosis? 
Select and explain. 
A. Giant cell arteritis, B. Wegner's granulomatosus, C. Microscopic polyangiitis, D. Takayasu arteritis
A: Giant cell arteritis
Answer: A: Giant cell arteritis 
Explanation: Ans. A. Giant Cell ArteritisImage Shows Enlarged Temporal Artery* Age >50yrs* New onset localized headache* Temporal: abnormalities- Decreased pulse- Tenderness and Nodules and thickening* Increased ESR >50* Positive temporal: biopsy (panarteritis, proliferation of the intima and fragmentation of internal elastic lamina)