This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Which of the following statement about Bradykinin is true? 
Select and explain. 
A. Causes pain, B. Causes bronchodilation, C. Causes vasoconstriction, D. Decreases vascular permeability
A: Causes pain
Answer: A: Causes pain 
Explanation: Bradykinin increases vascular permeability, causes contraction of smooth muscles (bronchoconstriction), dilatation of blood vessels and pain. Ref: Urinary Tract By Karl-Erik Andersson, Page 413; Peptidergic G Protein-coupled Receptors: From Basic Research to Clinical Applications By Pierangelo Geppetti, Page 100; The New Angiotherapy By Tai-Ping D. Fan, Elise C. Kohn, Page 94; Robbin's Illustrated Pathology, 7th Edition, Pages 65, 74, 75