This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Acquired multistep drug resistance can be seen in all except: 
Select and explain. 
A. Erythromycin, B. Streptomycin, C. Tetracycline, D. Chloramphenicol
B: Streptomycin
Answer: B: Streptomycin 
Explanation: Development of acquired resistance may be due to single-step mutation (as seen with streptomycin  and rifampicin) or multi-step mutation (erythromycin, tetracycline and chloramphenicol).