This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Epidemiology, Subject name: Social & Preventive Medicine
Temporal association of a disease is best established by 
Select and explain. 
A. Case-Control study, B. Cross-section study, C. Coho study, D. Descriptive study
C: Coho study
Answer: C: Coho study 
Explanation: Temporal relationship: Exposure must precede disease"A well-designed coho study is considered the most reliable means of showing an association between a suspected risk factor and subsequent disease"Park 23e pg:76