This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunology, Subject name: Microbiology
Which of the following does T cells independent Antigen acts through - 
Select and explain. 
A. T-cells, B. B-cells, C. macrophages, D. CD8+ T cells
B: B-cells
Answer: B: B-cells 
Explanation: T cell independent antigen stimulate antibody production by B cells without the apparent paicipation of T cells. Most microbial sugars , lipids and ceain nucleic acid are T cell independent antigens. Reference : Anathanarayan & paniker's 9th edition, pg no:90 <\p>