This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Medical & Surgical Illness Complication Pregnancy, Subject name: Gynaecology & Obstetrics
A woman who has developed chickenpox 2 days ago is admitted in labor.What is the best method to prevent infection in the neonate? 
Select and explain. 
A. Administer varicella zoster immunoglobulin (VZIG) to the neonate soon after birth, B. Administer varicella zoster vaccine to the neonate, C. Perform a cesarean section immediately, D. Prevent breastfeeding
A: Administer varicella zoster immunoglobulin (VZIG) to the neonate soon after birth
Answer: A: Administer varicella zoster immunoglobulin (VZIG) to the neonate soon after birth 
Explanation: Ans. is a, i.e. Administer varicella zoster immunoglobulin (VZIG) to the neonate soon after birthSince the mother developed the infection two days before the delivery, there is no time for the mother to develop antibodies. Therefore, the neonate will be non-immune and is at risk of developing chickenpox. Neonatal infection is prevented by giving VZIG to the neonate soon after birth.