This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Tumors, Subject name: Orthopaedics
Solitary bone lesion that does not arise from metaphysis is 
Select and explain. 
A. Giant cell tumour, B. Simple bone cyst, C. Aneurysmal bone cyst, D. Fibrous dysplasia
A: Giant cell tumour
Answer: A: Giant cell tumour 
Explanation: Differential diagnosis of a solitary bone lesion Features Giant cell tumour Simple bone cyst Aneurysmal bone cyst Fibrous dysplasia Age 20-40 yrs < 20 yrs 10-40 yrs 20-30 yrs Common bones Lower femur, Upper tibia Lower radius Upper humerus Upper femur Tibia, Humerus Neck of the femur, Tibia Location Epiphysis Metaphysis Metaphysis Metaphysis X-ray Soap-bubble appearance, Eccentrically placed Maximum width less than width of the growth plate Distending lesion, 'ballooning' the bone Multi-loculated Ground-glass appearance Trabeculations++ Treatment preferred Excision Curettage and bone graft Curettage and bone graft Curettage and bone graft Reference: Maheshwari; Essential Ohopaedics; Page no: 237