This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
How does metalloproteins prevent the development of jaundice? 
Select and explain. 
A. Decreasing RBC lysis, B. Inhibiting heme oxygenase, C. Increasing Y and Z receptors, D. Increasing glucoronyl transferase activity
B: Inhibiting heme oxygenase
Answer: B: Inhibiting heme oxygenase 
Explanation: Metalloproteins like Tin (Sn) and zinc (Zn) porphyrins and mesoporphyrins are under investigation for clinical use. These compounds inhibit the activity of heme oxygenase and thus decrease the formation of bilirubin, therby preventing the development of jaundice. Ref: Essential of PediatricsBy O P Ghai, 6th Edition, Page 173; Oxidative Stress and Free Radical Damage in Neurology By Natan Gadoth, Page 70.