This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Replication and transcription are similar processes in machanistic terms bacause both 
Select and explain. 
A. Use RNA primers for initiation, B. Use deoxyribonucleotides as precursors, C. Are semi conserved events, D. Involve phosphodiester bond formation with elongation occurring in the 5' - 3' direction
D: Involve phosphodiester bond formation with elongation occurring in the 5' - 3' direction
Answer: D: Involve phosphodiester bond formation with elongation occurring in the 5' - 3' direction 
Explanation: In both replication & transcription processes, the elongation occurs by the formation of phosphodiester bond in 5' → 3' direction.