This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Condition which presents as -nephritic syndrome with features of loss of foot processes on electron microscopy and poor response to coicosteroid therapy is:March 2012 
Select and explain. 
A. Postinfectious glomerulonephritis, B. Membranoproliferative glomerulonephritis type I, C. Minimal change disease, D. Focal segmental glomerulonephritis
D: Focal segmental glomerulonephritis
Answer: D: Focal segmental glomerulonephritis 
Explanation: Ans: D i.e. Focal segmental glomerulonephritisGlomerular pathology and presentationPostinfectious glomerulonephritis presents with nephritic syndrome and shows on subepithelial humps on electron microscopyMemranoproliferative glomerulonephritis type I present with nephritic/ nephrotic syndrome and shows su bend othelial deposits on electron microscopyMinimal change disease presents as nephrotic syndrome and shows loss of foot processes and no deposits on electron microscopyFocal segmental glomerulosclerosis presents as nephrotic syndrome; non nephrotic proteinuria and shows loss of foot processes and epithelial denudation on electron microscopy. It differs from minimal change disease in the fact that there is poor response to coicosteroid therapy.