This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Blood, Subject name: Pathology
Hypersplenism is characterized by all EXCEPT: 
Select and explain. 
A. Leukamoid reaction, B. Thrombocytopenia, C. Splenomegaly, D. Responds to splenectomy
A: Leukamoid reaction
Answer: A: Leukamoid reaction 
Explanation: (Leukamoid reaction): Ref: 704-R, 466-HM (476- Basic pathology 8th)HYPERSPLENISM - characterized by triad of1. Splenomegaly2. Anemia, leukopenia, thrombocytopenia or any combination of these, in association with hyperplasia of marrow precursors of the deficient cell type3. Correction of the blood cytopenia (s) by splenectomy* The term hypersplenism is usedfor conditions which causes excessive removal of erythrocytes, granulocytes or platelets from the circulation* Leukamoid reaction - defined as a reactive leukocytosis in the peripheral blood resembling that of leukaemia (413-HM)