This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Which of the following tumor does have perineural spread? 
Select and explain. 
A. Wahin's tumor, B. Mucoepidermoid carcinoma, C. Mixed tumors, D. Adenoid cystic tumor
D: Adenoid cystic tumor
Answer: D: Adenoid cystic tumor 
Explanation: Perineural spread from head and neck tumors most commonly occurs with squamous cell carcinoma and adenoid cystic carcinoma. Perineural spread most commonly involves cranial nerve V (all three divisions may be involved) and may be retrograde (toward the brain) or anterograde (toward the orbit). Perineural tumor extension is also seen in lymphoma, melanoma, rhabdomyosarcoma, and malignant nerve sheath tumors. To know - CN VII is the second most common cranial nerve affected by perineural invasion. Ref: Ophthalmic Oncology edited by Bita Esmaeli, 2010, Page 359; Textbook of dermatologic surgery by Rusciani Robins, Luigi Rusciani, Perry Robins, Page 454.