This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Orphan Annie nuclei" is seen in? 
Select and explain. 
A. Papillary carcinoma of thyroid, B. Medullary carcinoma of thyroid, C. Anaplastic carcinoma of thyroid, D. Follicular carcinoma of thyroid
A: Papillary carcinoma of thyroid
Answer: A: Papillary carcinoma of thyroid 
Explanation: Papillary carcinoma of thyroid REF: Schwaz's Principles of Surgery 9' edition chapter 38 Histologically, papillary carcinomas may exhibit papillary projections, a mixed pattern of papillary and follicular structures, or a pure follicular pattern (follicular variant). The diagnosis is established by characteristic nuclear cellular features. Cells are cuboidal with pale, abundant cytoplasm, crowded nuclei that may demonstrate "grooving," and intranuclear cytoplasmic inclusions leading to the designation of Orphan Annie nuclei, which allow diagnosis by FNAB.