This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
Kinky hair disease is a disorder where an affected child has peculiar white stubby hair, does not grow, brain degeneration is seen and dies by age of two years. Mrs A is hesitant about having children because her two sisters had sons who had died form kinky hair disease. Her mother's brother also died of the same condition. Which of the following is the possible mode of inheritance in her family – 
Select and explain. 
A. X–linked recessive, B. X–linked dominant, C. Autosomal recessive, D. Autosomal dominant
A: X–linked recessive
Answer: A: X–linked recessive 
Explanation: The clues in this question are -


Only males are manifesting disease.
Females are acting as carriers → sisters sons had suffered from the disease.


Both these are features of X-linked recessive disorders.

About other options

In X-linked dominant disorder the females will also manifest the disease.
In autosomal dominant and autosomal recessive disorders, both males and females are affected.