This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hematology, Subject name: Pharmacology
Which of the following plasminogen activator (fibrinolytic) can be given as bolus dose in patients with acute myocardial infarction: 
Select and explain. 
A. Urokinase, B. Alteplase, C. Reteplase, D. None
C: Reteplase
Answer: C: Reteplase 
Explanation: Essentials of medical pharmacology, seventh edition, page no =627 Answer is option3, reteplase It is a modified form of -PA that is longer acting, but somewhat less specific for fibrin bound plasminogen. The longer duration of action enables bolus dose administration, 10mg over 10 minutes repeated after 30minutes.