This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
All of the following are true of ß thalassemia major, except 
Select and explain. 
A. Increased osmotic fragility, B. Target cells on peripheral smear, C. Microcytic hypochromic anemia, D. Splenomegaly
A: Increased osmotic fragility
Answer: A: Increased osmotic fragility 
Explanation: in thalassemia major there will be marked splenomegaly,hypochromic microcytic anemia and target cells in peripheral smear.osmotic fragility decreases