This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Abdomen and pelvis, Subject name: Anatomy
Which is not true regarding Zona pellucida ? 
Select and explain. 
A. Surrounds morula, B. Acellular, C. Acetylcholine is the barrier, D. Surrounds the ovum
C: Acetylcholine is the barrier
Answer: C: Acetylcholine is the barrier 
Explanation: he zona pellucida (ZP) is a specialized extracellular matrix surrounding the developing oocyte (egg, ovum) within each follicle within the ovary. This thick matrix is thought to be formed by secretions from the oocyte and the follicle granulosa cells and in human oocytes consists of four types of zona pellucida glycoproteins ZP1, ZP2, ZP3and ZP4 which have different roles in feilization. The zona pellucid has many different roles including in oocyte development, protection during growth and transpo, feilization , spermatozoa binding, preventing polyspermy , blastocyst development, and preventing premature implantation . REF - pubmed.com