This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pathology
Raynaud's phenomenon is seen in 
Select and explain. 
A. SLE, B. Rheumatic fever, C. Hypeension, D. Diabetes mellitus
A: SLE
Answer: A: SLE 
Explanation: Raynaud phenomenon results from exaggerated vasoconstrictionof aeries and aerioles in the extremities, paicularlythe fingers and toes, but also sometimes the nose,earlobes, or lips. The restricted blood flow induces paroxysmalpallor or cyanosis; involved digits characteristicallyshow "red-white-and-blue" color changes from most proximalto most distal, reflecting proximal vasodilation, centralvasoconstriction, and more distal cyanosis, respectively.Raynaud phenomenon can be a primary entity or may besecondary to other disorders.Secondary Raynaud phenomenon refers to vascular insufficiencydue to aerial disease caused by other entitiesincluding systemic lupus erythematosus, scleroderma, Buerger disease, or even atherosclerosis.(Robbins Basic Pathology,9th edition,pg no.355)