This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Concept of health and disease, Subject name: Social & Preventive Medicine
The drug recommended for chemoprophylaxis 1 day before induction into high altitude areas is 
Select and explain. 
A. Acetazolamide, B. Furosamide, C. Doxycycline, D. Paracetamol
A: Acetazolamide
Answer: A: Acetazolamide 
Explanation: Acetazolamide is the drug of choice for Acute Mountain Sickness prevention. It inhibits renal carbonic anhydrase, causing a prompt bicarbonate diuresis that leads to metabolic acidosis and hyperventilation.Acetazolamide (125-250 mg twice a day), administered for 1 day before ascent and continued for 2 or 3 days, is effective. Higher doses are not required.Ref: Harrison&;s principles of Internal Medicine; 19th edition; Chapter 476e Altitude Illness