This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Autacoids, Subject name: Pharmacology
Ketanserine is 
Select and explain. 
A. 5HT 1b antagonist, B. 5HT2 antagonist, C. 5HT 1a agonist, D. 5HT 1d antagonist
B: 5HT2 antagonist
Answer: B: 5HT2 antagonist 
Explanation: 5-HT2A antagonistsEdit Antagonists of the 5-HT2A receptor are sometimes used as atypical antipsychotics(contrast with typical antipsychotics, which are purely dopamine antagonists). They include: Cyproheptadine blocks 5-HT2A, H1 and is a mild anticholinergic. Methysergide is a 5-HT2A antagonist and nonselective 5-HT1 receptor blocker. It causes retroperitoneal fibrosis and mediastinal fibrosis. Quetiapine blocks 5-HT2A, 5-HT1A, dopamine receptors D1 and D2, histamine receptor H1, and A1 adrenoreceptors. 5-HT2A/2C antagonistsEdit Ketanserin Antihypeensive. Blocks 5-HT2A, 5-HT2C and Alpha 1 (A1) adrenoreceptors. Risperidone antipsychotic Trazodone antidepressant Clozapine antipsychotic. Blocks 5-HT2A, 5-HT2C and D4 receptors. Nefazodone acts primarily as a potent 5-HT2A antagonist. Refer kDT 6/e p167