This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
True about Hybridoma: 
Select and explain. 
A. Immoalise myeloma cell, B. Hybridoma cell produced by fusion of T-cell & myeloma, C. Cell is of human origin, D. All
A: Immoalise myeloma cell
Answer: A: Immoalise myeloma cell 
Explanation: A i.e. Immoalise myeloma cell - Hybridoma is an immoal (permanent) cellQ produced by cell fusion of B cells (previously immunized or injected with antigen) and myeloma cells of mouseQ (or suitable animal). It produces monospecific monoclonal antibodiesQ which can be humanized (used in humans) by attaching the complementarity - determined regions , (the site that binds antigens) onto appropriate sites in human immunoglobulin molecule. Attempts to produce human monoclonal antibodies are underway. - Monoclonal antibodies are produced by hybridoma technology (in vitro) or by one clone secreting specific type of antibody in multiple myeloma (in vivo). It is required in minute (only microliter) quantities and can be used for blood groupingQ.