This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Asthma, Subject name: Pharmacology
Zileuton acts by - 
Select and explain. 
A. COX-II inhibitor, B. LOX-inhibitor, C. Mast cell stabilizers, D. M3 receptor blocker
B: LOX-inhibitor
Answer: B: LOX-inhibitor 
Explanation: (B) (LOX - Inhibitor) (229 - KDT 7th) (942 - Goodman & Gillman 12th)ZILEUTON* Zileuton, an inhibitor of 5 - LOX - and selective cysLT- receptor antagonists (Zafirlukast, pranlukast and Montelukast)* Treatment of mild to moderate asthma.* Duration of action is short and it has hepatotoxic.* Leukotriene antagonists - Montelukast, Zafirlukast.* Anti IgE - antibody - Omalizumab - uses moderate to severe allergic asthma.* Nodocromii is mast cell stabilizer.* Loading dose of Aminophylline is 5-6 mg/Kg*** Long acting beta - 2 (b2) agonist is - Salmctrol*** Albuterol - selective b2 receptor agonist.* Lctrozole is an aromatase inhibitor.