This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Primary Structural defect of an organ is termed: 
Select and explain. 
A. Malformation, B. Disruption, C. Deformation, D. Association
A: Malformation
Answer: A: Malformation 
Explanation: Primary structural defect of an organ is called as malformation. Primary malformations are caused by endogenous disturbances of the primordial tissues. Secondary malformations (disruptions) arise when organs develop abnormally from a normal primordium. Ref: Tanley L. Robbins, Ramzi S. Cotran, (2012) , Chapter 1, "Cell Injury", In the book, "Pocket Companion to Robbins and Cotran Pathologic Basis of Disease", 8th Edition, USA, Page 27 ; Robbin's Basic Pathology, 7th Edition, Pages 470-71