This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Anaesthesia
True about ester local anesthetics are all, EXCEPT: 
Select and explain. 
A. Unstable in solution, B. Hydrolyzed in plasma, C. Hydrolyzed by cholinesterase enzymes, D. None of the above
D: None of the above
Answer: D: None of the above 
Explanation: The ester and amide local anesthetics differ in their chemical stability, locus of biotransformation, and allergic potential. Amides are extremely stable, whereas esters are relatively unstable in solution. Aminoesters are hydrolyzed in plasma by cholinesterase enzymes, but the amides undergo enzymatic degradation in the liver Ref: Miller's anesthesia-7th ed, Chapter 30.