This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
Histamine causes all except - 
Select and explain. 
A. Aeriolar dilatation, B. Increased permeability of venules, C. Constriction of large aeries, D. Platelet aggregation
D: Platelet aggregation
Answer: D: Platelet aggregation 
Explanation: Histamine causes aeriolar dilation rapidly increases vascular permeability by inducing venular endothelial contraction formation of inter-endothelial gaps endothelial activation ref robbins pathology 9thed page 45