This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pharmacology
Which of the following drugs should NOT be used in the setting of severe hypeension in elderly on empirical basis? 
Select and explain. 
A. Enalapril, B. Amlodipine, C. Chlohiazide, D. Prazosin
D: Prazosin
Answer: D: Prazosin 
Explanation: For the elderly, alpha blockers like prazosin can cause severe hypotension and 1st dose hypotension DOC for elderly with severe HTN - CCBs DOC for HTN with diabetes- ARBs or ACE inhibitors Ref:Tripati 8th edition