This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
According to the myogenic hypothesis of renal autoregulation, the afferent arterioles contract in response to stretch induced by 
Select and explain. 
A. NO release, B. Noradrenaline release, C. Opening of Ca2+ channels, D. Adenosine release
C: Opening of Ca2+ channels
Answer: C: Opening of Ca2+ channels 
Explanation: According to the myogenic hypothesis of renal autoregulation, the afferent arterioles contract in response to stretch by the opening of Ca2+ channels, whereas, tubuloglomerular feedback is due to the opening of ligand-gated Ca2+ channels by adenosine.