This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Respiratory system, Subject name: Pharmacology
The following component of management protocol of status asthmaticus has now been shown to be useless 
Select and explain. 
A. Intravenous aminophylline, B. Intravenous hydrocoisone, C. Nebulized ipratropium bromide, D. Nebulized salbutamol
A: Intravenous aminophylline
Answer: A: Intravenous aminophylline 
Explanation: Status asthmaticus/Refractory asthma Any patient of asthma has the potential to develop acute severe asthma which may be life-threatening. Upper respiratory tract infection is the most common precipitant. Treatment of status asthmaticus:- (i) Hydrocoisone hemisuccinate 100 mg (or equivalent dose of another glucocoicoid) i.v. stat, followed by 100-200 mg 4-8 hourly infusion; may take upto 6 hours to act. (ii) Nebulized salbutamol (2.5-5 mg) + ipratro pium bromide (0.5 mg) intermittent inhalations driven by O2. (iii) High flow humidified oxygen inhalation. (iv) Salbutamol/terbutaline 0.4 mg i.m./s.c. may be added, since inhaled drug may not reach smaller bronchi due to severe narrowing/ plugging with secretions. (v) Intubation and mechanical ventilation, if needed. (vi) Treat chest infection with intensive anti biotic therapy. (vii) Correct dehydration and acidosis with saline + sod. bicarbonate/lactate infusion Ref:- kd tripathi; pg num :-233