This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
Cachectin is produced by- 
Select and explain. 
A. Neutrophils, B. Eosinophils, C. Macrophages, D. Basophils
C: Macrophages
Answer: C: Macrophages 
Explanation: Cachectin (Tumour necrosis factor - α) is produced by -

Macrophages
Monocytes
N.K. Cells

Biological effects of TNF-α

Tumor cytotoxicity
Induction of acute phase proteins
Lipolysis
Endotoxic shock
Fever
Antiviral and antiparasitic effect
Cachexia
Phagocytic cell activation