This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Pharmacology
Safe diuretic in renal dysfunction is 
Select and explain. 
A. Mannitol, B. Bumetinide, C. Chlohalidone, D. Acetazolamide
B: Bumetinide
Answer: B: Bumetinide 
Explanation: Loop diuretics are safe in renal dysfunction, liver cirrhosis and CCFRef: KDT 7THed Pg 581