This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Which of the following inhibits transcription ? 
Select and explain. 
A. Cyclosporine, B. Rapamycin, C. 5-Flurouracil, D. Cyclophosphamide
A: Cyclosporine
Answer: A: Cyclosporine 
Explanation: Ans. is 'a' i.e., Cyclosporine Cyclosporine inhibits transcription by binding to a protein called cyclophilin. This complex then inactivates calcineurin. (Calcineurin is a protein which is responsible for the transcription of cytokine gene)