This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Fibroids, Subject name: Gynaecology & Obstetrics
Red degeneration of fibroid occurs most commonly in: 
Select and explain. 
A. 3rd trimester, B. 2nd trimester, C. 1 st trimester, D. Postpaum
B: 2nd trimester
Answer: B: 2nd trimester 
Explanation: Red degeneration of fibroid : Most commonly in Second Trimester . Occurs when the fibroid overgrows its own blood supply. The middle of the fibroid becomes red and soft- a process known as Red degeneration - causing pain and possibly fever. Management of a fibroid with red degeneration in pregnancy is conservative. 'Never Operate' a fibroid in pregnancy since it can cause a lot of bleeding.