This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Pathology
A child presented with frothy urine, massive proteinuria and edema. Urine examination revealed RBC nil, WBC nil, nocasts, no crystal. No prior episode of similar presentation. What is your diagnosis? 
Select and explain. 
A. Minimal change disease, B. IgA nephropathy, C. Membranous glomerulonephritis, D. MPGN
A: Minimal change disease
Answer: A: Minimal change disease 
Explanation: Ans. (a) Minimal change disease(Ref: R 9th/pg 917-918)The child in this question presents with first episode of massive proteinuria, frothy urine suggestive of lipiduria and edema. Urine microscopy finding is not significant. This is suggestive of nephrotic syndrome, for which, the most common cause in children is Minimal change disease.