This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
The pathognomonic feature of classic alpo syndrome is: 
Select and explain. 
A. Lenticonus and hematuria, B. Hematuria and sensorineural hearing loss, C. Sensorineural hearing loss and lenticonus, D. Hematuria and hyperextensibility of joints
A: Lenticonus and hematuria
Answer: A: Lenticonus and hematuria 
Explanation: The diagnosis of classic alpo syndrome is based on X-linked inheritance of hematuria, sensorineural hearing loss, and lenticonus. The lenticonus together with hematuria is pathognomonic of classic Alpo syndrome. Reference: Harrisons Principles of Internal Medicine, 18th Edition, Pages 3213-14