This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Blood Bank & Transfusion Therapy, Subject name: Medicine
Acute renal failure in a patient who received incompatible blood transfusion with hemolytic reaction is best managed by: 
Select and explain. 
A. 20% Mannitol, B. IV fluids with K+ supplementation, C. Alkalinizing the urine, D. Stopping blood transfusion
D: Stopping blood transfusion
Answer: D: Stopping blood transfusion 
Explanation: Microvascular thrombosis and deposition of haemoglobinin the distal renal tubule can result in acute renal failure. The extent of precipitation is inversely related to urine flow.I.V. fluids, vasopressors and diuretics should be given to maintain renal perfusion pressure, and to produce a diuresis. If acute renal failure develops, hemofiltration should be considered.