This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.N.S, Subject name: Medicine
Which of the following PDE- 5 inhibitor has no interaction with high fat meal intake 
Select and explain. 
A. Sidenafil, B. Vardenafil, C. Tadalafil, D. All of the above
C: Tadalafil
Answer: C: Tadalafil 
Explanation: High fat meal interferes with absorption of sildenafil and vardenafil but not tadalafil.