This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Pharmacotherapy in psychiatry, Subject name: Psychiatry
which of the following is a SNRI 
Select and explain. 
A. duloxetine, B. seraline, C. citalopram, D. ironiazid
A: duloxetine
Answer: A: duloxetine 
Explanation: SNRI * IMPOANCE Dual antidepressant like TCA but better than TCA has it has no dryness of mouth, hypotension, sedation * MECHANISM Inhibits the reuptake of both serotonin and dopamine * DRUGS VENLEFEXINE DESVENLEFEXINE DULOXETINE * USE Duloxetine===PAIN ASSOSIATED WITH DIABTIC NEUROPATHY and STRESS URINARY INCONTINENCE Milnacipran===Fibromyalgia * SIDE EFFECTS DIASTOLIC HYPEENSION DELAYED ORGASM WITHDRAWL SYNDROME ON DISCONTINUATION, hence should not be abruptly stopped. To try slow tapering Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 955