This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immune system, Subject name: Medicine
C-ANCA associated with 
Select and explain. 
A. Wegener's granulomatosis, B. Microscopic polyangitis, C. Churg straus syndrome, D. PAN
A: Wegener's granulomatosis
Answer: A: Wegener's granulomatosis 
Explanation: C-ANCAs, or PR3-ANCA, or Cytoplasmic antineutrophil cytoplasmic antibodies, are a type of autoantibody, an antibody produced by the body that acts against one of its own protein . PR3 is the most common antigen target of ANCA in patients with granulomatosis with polyangiitis. Ref - Researchgate.net