This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Renal physiology, Subject name: Physiology
Ethanol increases urine output by 
Select and explain. 
A. Inhibiting Na+ reabsorption, B. Suppressing ADH secretion, C. Increasing glomerular filtration rate, D. Suppressing H+ secretion
B: Suppressing ADH secretion
Answer: B: Suppressing ADH secretion 
Explanation: Alcohol inhibits the pituitary secretion of anti-diuretic hormone (ADH), which acts on the kidney to reabsorb water. Alcohol acts on the hypothalamus/pituitary to reduce the circulating levels of ADH. When ADH levels drop, the kidneys do not reabsorb as much water; consequently, the kidneys produce more urine.Ref: Ganong&;s Review of Medical Physiology, 23rd edition, page no: 667