This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Urinary tract, Subject name: Pathology
Antiglomerular basement antibody is seen in- 
Select and explain. 
A. Membranous glomerulonephritis, B. Goodpasture's syndrome, C. Alpo's syndrome, D. Henoch-Schonlein purpura
B: Goodpasture's syndrome
Answer: B: Goodpasture's syndrome 
Explanation: Goodpasture's syndrome is characterized by acute renal failure due to RPGN and pulmonary hemorrhages. The disease results from damage to the glomeruli by anti-GBM antibodies which cross-react with alveolar basement membrane and hence, produce renal as well as pulmonary lesions. The evidence in suppo is the characteristic linear deposits of anti-GBM antibodies consisting of IgG and complement along the GBM, detection of circulating anti-GBM antibodies and induction of glomerular lesions with an injection of anti-GBM antibodies experimentally in monkeys Ref: Textbook of pathology Harsh Mohan 6th edition page 667