This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Anaesthesia
The definite contraindication of Thiopentone 
Select and explain. 
A. Diabetic patient, B. ECT, C. Sarcoidosis, D. Acute intermittant porphyria
D: Acute intermittant porphyria
Answer: D: Acute intermittant porphyria 
Explanation: (D) Acute intermittant porphyria # Barbiturates are Contraindicated in -- H/O Barbiturate hypersensitivity H/O Acute intermittent porphyria (cause LMN paralysis or CVS collapse);Anticipated airway obstruction> Care: Fixed cardiac output states; Shock states; Hepatic/Renal dysfunction; Asthmatic/Myxoedema; Adrenocortical failure; Myotonia dystrophia; Extremes of age.