This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Rheumatoid Arthritis, Subject name: Medicine
Rheumatoid arthritis is seen with? 
Select and explain. 
A. HLADR3, B. HLA DR4, C. HLA DR 27, D. HLA B 27
B: HLA DR4
Answer: B: HLA DR4 
Explanation: Ans. (b) HLADR4Ref: Harrison 19th ed. / 372e-lHLA alleleDiseases with increased riskHLA-B27Ankylosing spondylitisPost-gonococcal arthritisAcute anterior uveitisHLA-B4721-hydroxylase deficiencyHLA-DR2Systemic lupus erythematosusHLA-DR3Autoimmune hepatitisPrimary Sjogren syndromeDiabetes mellitus type 1Systemic lupus erythematosusHLA-DR4Rheumatoid arthritisDiabetes mellitus type 1HLA-DR3 and - DR4 combinedDiabetes mellitus type 1HLA-DQ2 and HLA-DQBCeliac disease