This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Diuretics and Antidiuretics, Subject name: Pharmacology
The site of action of the furosemide is: 
Select and explain. 
A. Thick ascending limb of loop of Henle, B. Descending limb of loop of Henle, C. Proximal convoluted tubule, D. Distal convoluted tubule
A: Thick ascending limb of loop of Henle
Answer: A: Thick ascending limb of loop of Henle 
Explanation: Ans. (A) Thick ascending limb of loop of Henle(Ref: Goodman and Gilman 12th/678)Furosemide is a loop diuretic and this group of drugs act on thick ascending limb of loop of Henle.