This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology metabolism, Subject name: Physiology
Hormone with distant site of action acts - 
Select and explain. 
A. Autocrine, B. Paracrine, C. Endocrine, D. Any of the above
C: Endocrine
Answer: C: Endocrine 
Explanation: Ans. is 'c' i.e., Endocrine o Hormones are chemical mediators that control cellular functions. They are secreted into the blood stream by ductless endocrine glands and thereby exert widespread actions.o Hormone may have : -i) Autocrine action: - Acts on the cell from which it is secreted.ii) Paracrine action: - Acts on neighboring cells, e.g., the effect of gastrin on D cells secreting somatostatin.iii) Endocrine action: - Acts on cells distant to the cell from which it is secreted. Most of the hormones act by this mechanism.