This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pathology
Not a feature of rheumatic hea disease - 
Select and explain. 
A. Chorea, B. Ahritis, C. Janeways lesion, D. Carditis
C: Janeways lesion
Answer: C: Janeways lesion 
Explanation: Acute rheumatic fever occurs most often in children; the principal clinical manifestation is carditis. Neveheless, about 20% of first attacks occur in adults, with ahritis being the predominant feature. Symptoms in all age groups typically begin 2 to 3 weeks after streptococcal infection, and are heralded by fever and migratory polyahritis-- one large joint after another becomes painful and swollen for a period of days, followed by spontaneous resolution with no residual disability. (1) carditis; (2) migratory polyahritis of large joints; (3) subcutaneous nodules; (4) erythema marginatum skin rashes; and (5) Sydenham chorea, (Robbins basic pathology,9th edition,pg no.392)