This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Renal carcinoma, Subject name: Pathology
Which of the following genes is associated with Xp11 translocation carcinoma variant of renal cell carcinoma? 
Select and explain. 
A. VHL, B. TFE3, C. MET, D. TSC1
B: TFE3
Answer: B: TFE3 
Explanation: Xp11 translocation Carcinoma: It is a rare genetically distinct subtype of renal cell carcinoma. More common in children. TFE3 gene located at Xp11.2 locus is involved The neoplastic cells consist of clear cytoplasm with a papillary architecture. VHL is associated with clear cell RCC. MET is associated with hereditary papillary RCC. TSC1 is associated with renal angiomyolipoma.