This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Microbiology
Which is not true regarding superantigen? 
Select and explain. 
A. Bind T cells irrespective of antigen specificity of TCR, B. Bind directly to both MHC II and T cell receptor causing T cell activation, C. Bind to cleft (antigen binding groove) in the MHC II molecule, D. Binds directly to lateral aspect of T cell receptor
C: Bind to cleft (antigen binding groove) in the MHC II molecule
Answer: C: Bind to cleft (antigen binding groove) in the MHC II molecule 
Explanation: .