This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Most common translocation in acute promyelocytic leukemia (APML) is 
Select and explain. 
A. t (8:14), B. t (9:22), C. t (15:17), D. t (8:21)
C: t (15:17)
Answer: C: t (15:17) 
Explanation: Answer- C, t (15:17)Acute promyelocytic leukemia (M3 by the FAB classification) is associated with a t(15;17) (q22;q11) translocation.Disseminated intravascular coagulation can occur in this disorder due to the release of procoagulant substances from the leukemic cells, especially during treatment.The t(4;11)(q21;q23) translocation is associated with acute lymphocytic leukemia (ALL) and undifferentiated leukemia.The t(6;9)(p23;q34) translocation is found in subtypes of AML with basophilia (M1, M2, M4).Burkitt's leukemia, which is related to Burkitt's lymphoma, is associated with t(8;14) (q 24;q32).The t(8;21) (q22;q22) translocation (choice D) is seen in M2 leukemia, also known as acute myeloid leukemia (AML) with maturation