This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Pharmacokinetics, Subject name: Pharmacology
Which of the following metabolic reactions is not catalysed by microsomal enzymes? 
Select and explain. 
A. Glucuronidation, B. Acetylation, C. Oxidation, D. Reduction
B: Acetylation
Answer: B: Acetylation 
Explanation: PHASE 1 * Oxidation * Reduction All are catalysed by microsomal enzymes PHASE 2 * Glucuronidation * Acetylation * Methylation All are catalyzed by non microsomal enzymes except glucuronidation which is catalysed by microsomal enzymes.