This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Medicine
Kimmelstiel-Wilson lesions are characteristically seen in- 
Select and explain. 
A. Systemic lupus erythematosus, B. Amyloidosis, C. Malignant hypeension, D. Diabetic nephropathy
D: Diabetic nephropathy
Answer: D: Diabetic nephropathy 
Explanation: Diabetic nephropathy - Within 1-2 yrs after onset of clinical diabetes , morphologic changes appear in the kidney. Thickening of GBM is a sensitive indicator for the presence of diabetes . mesangial sclerosis ( accumulation of extracellular matrix in mesangium) is seen . Some patients also develop eosinophilic ,PAS +nodules called kimmelsteil -Wilson nodules . prominent vascular changes are frequently seen with Hyaline and hypeensive aeriosclerosis . Ref:Harrison 20 th edition pg no 2144