This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
Which among the following is an absolute contraindication of Hormone replacement therapy ? 
Select and explain. 
A. Endometriosis, B. Osteoahritis, C. Hea disease, D. Breast carcinoma
D: Breast carcinoma
Answer: D: Breast carcinoma 
Explanation: Absolute contraindications of hormone replacement therapy (H): Undiagnosed vaginal bleeding Estrogen dependent cancer in the body Severe liver disease Pregnancy Venous thrombosis Well-differentiated and early endometrial cancer (once treatment for the malignancy is complete, is no longer an absolute contraindication.)