This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti Diabetes, Subject name: Pharmacology
Rosiglitazone mechanism of action is - 
Select and explain. 
A. Acts as PPAR gamma agonist, B. Inhibitor of alpha glucosidase, C. Acts as amyl in analogue, D. Acts as dipeptidy! peptidase inhibitor
A: Acts as PPAR gamma agonist
Answer: A: Acts as PPAR gamma agonist 
Explanation: Ans. is "a' i.e., Acts as PPAR gamma agonist [Ref KDT 7*/ep. 276\Rosiglitazoneo It is oral antidiabetic drugo They are selective agonists for nuclear peroxisome proliferator activator receptor gamma (PPAR gamma) expressed in the fat and muscle cells.o It enhances transcription of several insulin responsive genes,o Reverse insulin resistance by enhancing GLUT 4 expression and translocation.