This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: New Born Infants, Subject name: Pediatrics
A newborn presented with jaundice. Most diagnostic investigation of choice is: 
Select and explain. 
A. Total and Direct bilirubin, B. Conjugated bilirubin, C. Serum, bilirubin, D. Uroporphyrin levels
A: Total and Direct bilirubin
Answer: A: Total and Direct bilirubin 
Explanation: a. Total and Direct bilirubin(Ref: Nelson's 20/e p 871-879, Ghai 8/e p 172-176)Measurement of total & direct bilirubin will help to classify jaundice into its respective type and aid in diagnosis.