This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Medicine
Excessive production of aldosterone results in - 
Select and explain. 
A. Metabolic acidosis, B. Severe hypotension, C. Potassium retention, D. Depressed plasma renin
D: Depressed plasma renin
Answer: D: Depressed plasma renin 
Explanation: Because of increased aldosterone there will be negative feedback on renin which lead to decreased renin production Primary hyperaldosteronism is one of the cause for LOW RENIN hypeension (Reference Harrison 20 th edition page no 2729)