This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Most impoant amino acid for formation Neutrophilic extracellular trap is ? 
Select and explain. 
A. Leucine, B. Methionine, C. Citrulline, D. Valine
C: Citrulline
Answer: C: Citrulline 
Explanation: Answer- C. CitrullinePositively charged arginine is conveed to neutral amino acid citrulline by the enzyme peptidyl arginine deaminase (citrullination).Citrullination is an essential step of NET formation.NETs proiile for a high local concentration of antimicrobial componenk such as neutrophil elastase, cathepsin G and histones, that have a high affinity for DNA.