This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Inborn Errors of Metabolism, Subject name: Pediatrics
Menke's disease is due to defect in the metabolism of: 
Select and explain. 
A. Zinc, B. Copper, C. Selenium, D. Iron
B: Copper
Answer: B: Copper 
Explanation: b. Copper(Ref: Nelson 20/e p 344)In Menke's disease, the defective protein is a copper-binding ATPase (ATP7A), responsible for distribution & metabolism of copper in tissues.