This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Anatomy
Bile ductopenia seen in 
Select and explain. 
A. GVHD, B. Alcoholic hepatitis, C. Autoimmune hepatitis, D. Cirrhosis
A: GVHD
Answer: A: GVHD 
Explanation: Ductopenia Ductopenia refers to a reduction in the number of ducts in an organ. It is the histological hallmark of vanishing bile duct syndrome (typically <0.5 bile ducts per poal triad). The most common cause of ductopenia is primary biliary cholangitis. Other causes failing liver transplant Hodgkin's lymphoma graft-versus-host disease (GVHD) sarcoid cytomegalovirus infection, HIV medication toxicity. Ref: Harrison's 19th edition Pgno :2027-2028