This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.N.S, Subject name: Pharmacology
Best drug for chronic gout in patient with renal impairment is: 
Select and explain. 
A. Naproxen, B. Probenecid, C. Allopurinol, D. Sulfinpyrazone
C: Allopurinol
Answer: C: Allopurinol 
Explanation: Ans. (C) Allopurinol(Ref: KDT 8th/e p217)*NSAIDs like naproxen have no role in chronic gout*Uricosuric drugs like probenecid and sulfinpyrazone are ineffective in the presence of renal insufficiency*Allopurinol is drug of choice for most cases of chronic gout.