This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nervous system, Subject name: Pathology
True about prions are all except - 
Select and explain. 
A. Cannot be inherited, B. Can occur sporadically, C. Can be transmitted corneal transplant, D. Can be transmitted human growth hormone preparation
A: Cannot be inherited
Answer: A: Cannot be inherited 
Explanation: Familial forms of prion disease are inherited in an autosomal dominant pattern, which means one copy of the altered PRNP gene in each cell is sufficient to cause the disorder. In most cases, an affected person inherits the altered gene from one affected parent.