This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.V.S, Subject name: Medicine
In gram negative septicemia, early findings setting before shock of florid is - 
Select and explain. 
A. | Cardiac output, T Total peripheral resistance, B. |Cardiac output, i Total peripheral resistance, C. |Cardiac output, t Total peripheral resistance, D. |Cardiac output, i Total peripheral resistance
B: |Cardiac output, i Total peripheral resistance
Answer: B: |Cardiac output, i Total peripheral resistance 
Explanation: The pathophysiology of septic shock is not entirely understood, but it is known that a key role in the development of severe sepsis is played by an immune and coagulation response to an infection. Septic shock involves a widespread inflammatory response that produces a hypermetabolic effect in septic shock |Cardiac output, i Total peripheral resistance Ref Davidson 23rd edition pg 445