This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Techniques in molecular biology, Subject name: Biochemistry
For karyotyping, the dividing cells are arrested by the addition of colchicines in the following mitotic phase: 
Select and explain. 
A. Telophase, B. Metaphase, C. Anaphase, D. Prophase
B: Metaphase
Answer: B: Metaphase 
Explanation: Colchicine is used during karyotyping to arrest the cell in metaphase In metaphase , all chromosomes lie at the equator