This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Medicine
A patient presented with pulmonary embolism the treatment to be given is 
Select and explain. 
A. Urokinase with fibrinolytics, B. i.v. Heparin with continuous infusion followed by coumarin for 4-5 months, C. Subcutaneous Heparin 5000 units, D. Warfarin with INR 1-1.5
B: i.v. Heparin with continuous infusion followed by coumarin for 4-5 months
Answer: B: i.v. Heparin with continuous infusion followed by coumarin for 4-5 months 
Explanation: (B) i.v. Heparin with continuous infusion followed by coumarin for 4-5 months # Thrombolysis:> Successful thrombolytic therapy rapidly reverses right heart failure and leads to a lower rate of death and recurrent PE.# Thrombolysis usually:> Dissolves much of the anatomically obstructing pulmonary arterial thrombus;> Prevents the continued release of serotonin and other neurohumoral factors that exacerbate pulmonary hypertension; and Dissolves much of the source of the thrombus in the pelvic or deep leg veins, thereby decreasing the likelihood of recurrent PE.> The preferred thrombolytic regimen is 100 mg of recombinant tissue plasminogen activator (tPA) administered as a continuous peripheral intravenous infusion over 2 h.> Patients appear to respond to thrombolysis for up to 14 days after the PE has occurred.> Contraindications to thrombolysis include intracranial disease, recent surgery, or trauma. There is a 1 to 2% risk of intracranial hemorrhage.> Careful screening of patients for contraindications to thrombolysis is the best way to minimize bleeding risk.