This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Most common missing tooth in the permanent dentition is: 
Select and explain. 
A. Maxillary canine, B. Maxillary first molar, C. Mandibular second premolar, D. Mandibular first molar
C: Mandibular second premolar
Answer: C: Mandibular second premolar 
Explanation: None