This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Diabetes, Subject name: Pathology
Most characteristic feature of diabetic nephropathy: 
Select and explain. 
A. Kimmelstein Wilson change, B. Armani Ebstein change, C. Focal segmental glomerulosclerosis, D. Membrano proliferative glomerulonephritis
A: Kimmelstein Wilson change
Answer: A: Kimmelstein Wilson change 
Explanation: Features of diabetic nephropathy are: - Glomerular lesions like Capillary basement membrane thickening - Earliest & most common change in DM Diffuse mesangial sclerosis - presents as nephrotic syndrome in severe cases Nodular glomerulosclerosis aka Kimmelstiel-Wilson lesion - Pathognomonic of diabetes -Renal vascular lesions, principally aeriolosclerosis -Pyelonephritis, including necrotizing papillitis.