This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Muscle Relaxant, Subject name: Anaesthesia
Effects of d-tubocurarine are reversed by? 
Select and explain. 
A. Atropine, B. Neostigmine, C. Succinylcholine, D. Barbiturates
B: Neostigmine
Answer: B: Neostigmine 
Explanation: Ans. is 'b' i.e., Neostagmine * d-tubocurarine is a non-depolarizing blocker. For reversal of non-depolarizing blocker, anticholinesterases are used. They increase the concentration of Ach by inhibiting its degradation by cholinesterase.* Most commonly neostigmine is used. Other drugs are edrophonium, Pyridostigmine, Physiostigmine.* Atropine is given to prevent muscarinic side effects of neostigmine (it does not cause reversal).Remember* Neostigmine does not antagonise depolarising blockers (Therefore cannot be used for reversal). Infact neostigmine can potentiate the block as neostigmine and other anti- cholinesterase also inhibits pseudocholinesterase which metabolizes Sch.