This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunomodulator, Subject name: Pharmacology
Cyclosporine is active against 
Select and explain. 
A. CD4+ lymphocyte, B. CD8+ lymphocyte, C. CD 14+ lymphocyte, D. B lymphocyte
A: CD4+ lymphocyte
Answer: A: CD4+ lymphocyte 
Explanation: Ans. is 'a' i.e., CD4+ Lymphocyte Cyclosporine acts on cell mediated immunity It profoundly and selectively inhibitsT Lymphocyte proliferation (CD4+ Cells)IL-2 and other cytokine proliferationResponse of inducer T cells to IL-1It does not has any effect on suppressor cells.