This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Anatomy
Which of the following increases the susceptability to corornary aery disease? 
Select and explain. 
A. Type V hyperlipoprotenemia, B. Von willibrand disease, C. Nephrotic syndrome, D. Systemic lupus erythematosus
C: Nephrotic syndrome
Answer: C: Nephrotic syndrome 
Explanation: Nephrotic syndrome is a clinical complex characterized by protenuria,hypoalbunemia,edema and hyperlipedemia. A hypercoaguble state frequently accompanied by severe nephrotic syndrome due to urinary loss of AT-III reduced serum levels of protein C and S hyper fibrogenemia and enhanced platelet aggregation. Due to increased coagulation state,predisposing to CAD is present in patients with nephrotic syndrome (ref Harrisons 17th/272)