This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Lipoproteins, Subject name: Biochemistry
HDL is synthesized and secreted from : 
Select and explain. 
A. Liver, B. Peripheral tissue, C. Adipose tissue, D. Muscle
A: Liver
Answer: A: Liver 
Explanation: HDL- HDL is synthesized and secreted from both liver and intestine HDL HDL transpo cholesterol from peripheral tissue to the liver this is called reverse cholesterol transpo. HDL concentrations are inversely related to the incidence of atherosclerosis HDL have APO A, C, and E HDL have LCAT (Lecithin cholesterol acyltransferase ) which conve cholesterol into cholesterol ester and then it is taken up by HDL LCAT is activated by APOA1 HDL is smallest in size, max density, max phospholipid (lecithin) , minimum triglyceride