This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of lipid, Subject name: Biochemistry
Lack of beta-oxidation of fatty acid leads to? 
Select and explain. 
A. Oxidation of branched chain fatty acids, B. Phytanic acid accumulation, C. Dicarboxylic acid accumulation, D. Formation of propionic acid
C: Dicarboxylic acid accumulation
Answer: C: Dicarboxylic acid accumulation 
Explanation: Lack of beta-oxidation of fatty acids leads to the accumulation of dicarboxylic acids. Dicarboxylic aciduria is caused by a lack of mitochondrial medium-chain acylCoA dehydrogenase. It is characterized by 1. Excretion of C -C o-dicarboxylic acids in the urine. 2.Nonketotic hypoglycemia Reference: Harper's Illustrated Biochemistry 31st edition Pg 215