This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Adrenergic System, Subject name: Pharmacology
Alpha 2 agonist causes all except: 
Select and explain. 
A. Anxiolysis, B. Sedation, C. Analgesia, D. Hyperalgesia
D: Hyperalgesia
Answer: D: Hyperalgesia 
Explanation: Ans. D. Hyperalgesiaa. The alpha-2 adrenergic receptor is a G protein-coupled receptor (GPCR). Catecholamines like nor-epinephrine (noradrenaline) and epinephrine (adrenaline) signal through the alpha2-adrenergic receptor in the central and peripheral nervous systems.b. Alpha-2 agonists provide sedation, analgesia, muscle relaxation and anxiolysis.