This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pharmacology
The following drug has significant drug interaction with the digoxin except 
Select and explain. 
A. Cholestyramine, B. Thiazide diuretics, C. Quinidine, D. Amlodipine
D: Amlodipine
Answer: D: Amlodipine 
Explanation: Cholistyramine inhibits intestinal absorption of digoxin Thiazides result in hypokalemia and thus me precipitate digitalis toxicity by pharmacodynamic interaction Quinidine and verapamil reduces the excretion of digoxin and Thus may precipitate the toxicity(pharmakokinetic interaction) Refer kDT 6/e p499