This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pharmacology, Subject name: Pharmacology
If there is a Gs alpha subunit gain-of-function mutation, this results in: 
Select and explain. 
A. Decreased cAMP, B. Decreased 1P3, C. Increased GTPase activity, D. Increased cAMP
D: Increased cAMP
Answer: D: Increased cAMP 
Explanation: Gs activates Ca++ channel opening Gs-increases cAMP by stimulating adenyl cyclase Gi(inhibitory)- decreases cAMP by inhibiting adenyl cyclase Pg.no45 KD TRIPATHI SEVENTH EDITION