This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Drugs, Subject name: Medicine
Drug effective pharmacologic interventions for management of smoking cessation 
Select and explain. 
A. Bupropion, B. Varenicline, C. Clonidine, D. All of the above
D: All of the above
Answer: D: All of the above 
Explanation: Ans. d (All of the above) (Ref. H-17th/1641; Table 390-3)Effective pharmacologic interventions for cesation of smoking:First-line therapiesSecond-line therapies# Nicotine gum# Clonidine# Nicotine patch# Nortriptyline# Nicotine nasal inhaler # Nicotine oral inhaler # Nicotine lozenge # Bupropion # Varenicline