This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Infectious disease, Subject name: Pediatrics
Thrombocytopenia, macerated skin lesions, rash and periostitis in a new born are seen in 
Select and explain. 
A. Erythroblastosis fetalis, B. Cytomegalovirils infection, C. Syphilis, D. HIV infection
C: Syphilis
Answer: C: Syphilis 
Explanation: In Syphilis, thrombocytopenia is often associated with platelet trapping in an enlarged spleen. Characteristic osteochondritis and periostitis and a mucocutaneous rash manifesting with erythematous maculopapular or vesiculobullous lesions followed by desquamation involving hands and feet are common. Reference : Nelson textbook of pediatrics 19th edition Page 1017 & 1018