This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pharmacology, Subject name: Pharmacology
Which of the following group of drugs follows zero order kinetics with high dose 
Select and explain. 
A. Phenytoin and Propranolol, B. Amiloride and probenacid, C. Alcohol and theophylline, D. Digoxin and propranolol
C: Alcohol and theophylline
Answer: C: Alcohol and theophylline 
Explanation: drugs which follow zero order kinetics- methanol, ethanol mixed order - 1st order at a low dose and zero order at high dose- aspirin, phenytoin, tolbutamide, digoxin, warfarin, theophylline most of the drugs usually follow 1st order kinetics and they are considered safe drugs Ref: KD Tripathi 8th ed