This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.V.S, Subject name: Pediatrics
All are major manifestation of theumatic fever and rheumatic hea diease except 
Select and explain. 
A. Carditis, B. Elevated antiistreptolysin-O, C. Polyahritis, D. Erythema marginatum
B: Elevated antiistreptolysin-O
Answer: B: Elevated antiistreptolysin-O 
Explanation: Major criteria of RHD include card it is,chorea,ahritis, subcutaneous nodule, erythema marginatum. Ref : Ghai essential of pediatrics, eighth edition ,p.no:436