This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Clinical manifestations of acute glomerulonephritis include which of the following? 
Select and explain. 
A. Chills and flank pain, B. Oliguria and generalized edema, C. Hematuria and proteinuria, D. Dysuria and hypotension
C: Hematuria and proteinuria
Answer: C: Hematuria and proteinuria 
Explanation: Hematuria and proteinuria indicate acute glomerulonephritis.
These finding result from increased permeability of the glomerular membrane due to the antigen-antibody reaction. 
Generalized edema is seen most often in nephrosis.