This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Acetazolamide decreases intraocular pressure by what mechanism: September 2010 
Select and explain. 
A. Decreases aqueous humor production, B. Decreases vitreous volume, C. Increased drainage of aqueous, D. None of the above
A: Decreases aqueous humor production
Answer: A: Decreases aqueous humor production 
Explanation: Ans. A: Decreases aqueous humor production Acetazolamide is a carbonic anhydrase inhibitor, which means that it forces the kidneys to excrete bicarbonate (HCO;), thus re-acidifying the blood. It also lowers intraocular tension by decreased formation of aqueous humour (It is rich in bicarbonate)