This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
The pharmacokinetic propeies of a new drug are being studied in normal volunteers during phase I clinical trials. The volume of distribution and clearance determined in the first subject are 40 L and 2.0 L/hour, respectively. The half-life of the drug in this subject is approximately? 
Select and explain. 
A. 2, B. 6, C. 14, D. 21
C: 14
Answer: C: 14 
Explanation: The half-life of a drug can be determined using the following equation: t1/2 = (0.693 x Vd)/Cl =0.693 X 40/2 = 13.86 ~14. Ref: Buxton I.L., Benet L.Z. (2011). Chapter 2. Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination. In L.L. Brunton, B.A. Chabner, B.C. Knollmann (Eds), Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e.