This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Wilson Disease, Subject name: Medicine
Menke's kinky (Steely) hair disease occurs due to: 
Select and explain. 
A. Low copper levels, B. Low zinc levels, C. Low iron levels, D. Low fluoride levels
A: Low copper levels
Answer: A: Low copper levels 
Explanation: Menke's kinky hair disease- X-linked defect in intestinal absorption of copper. Mutation in ATP7A gene. Low levels of copper and ceruloplasmin. C/F- Progressive cerebral degeneration, growth retardation Sparse brittle hair Scurvy-like bone changes Anemia and neutropenia Failure to thrive Pili toi, trichorrhexis and monilethrix may occur.