This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Marfan’s syndrome is due to defect of? 
Select and explain. 
A. Elastin, B. Collagen, C. Fibrillin, D. Lamillin
C: Fibrillin
Answer: C: Fibrillin 
Explanation: “Marfan's syndrome caused by a recurrent de novo missense mutation in the fibrillin-1 gene”
√ Mutations in the fibrillin-1 gene cause Marfan's syndrome
√ Mutations in the fibrillin-2 gene have been linked to Beals Syndrome.