This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
All are a major manifestation of rheumatic fever and rheumatic heart disease except 
Select and explain. 
A. Carditis, B. Elevated antiistreptolysin-O, C. Polyarthritis, D. Erythema marginatum
B: Elevated antiistreptolysin-O
Answer: B: Elevated antiistreptolysin-O 
Explanation: major criteria of RHD include card it is,chorea,arthritis, subcutaneous nodule, erythema marginatum