This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nervous system, Subject name: Physiology
Prolactin release is inhibited by 
Select and explain. 
A. Dopamine, B. Dobutamine, C. Sleep, D. Stress
A: Dopamine
Answer: A: Dopamine 
Explanation: Dopamine serves as the major prolactin-inhibiting factor or brake on prolactin secretion. Dopamine is secreted into poal blood by hypothalamic neurons, binds to receptors on lactotrophs, and inhibits both the synthesis and secretion of prolactin. Ref: guyton and hall textbook of medical physiology 12 edition page number: 550,551,552