This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Mycobacterial Diseases (TB, Leprosy and MAC), Subject name: Pharmacology
Thalidomide is useful in which of the following conditions? 
Select and explain. 
A. Treatment of leprosy, B. Treatment of type II lepra reaction, C. Treatment of type I lepra reaction, D. Treatment of neuritic leprosy
B: Treatment of type II lepra reaction
Answer: B: Treatment of type II lepra reaction 
Explanation: Lepra Reaction TYPE 1 LEPRA REACTION TYPE 2 LEPRA REACTION - It is also known as reversal reaction. - It is seen in TT and BL cases of leprosy. - Drug of choice is coicosteroids. Alternative is clofazimine. - Thalidomide is ineffective. - It is also known as erythema nodosum leprosum. - It is seen in LL cases of leprosy. - Drug of choice is coicosteroids. Alternative is clofazimine. - Thalidomide is useful in severe cases.