This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
In gout tophi are not seen in? 
Select and explain. 
A. Skin, B. Muscles, C. Nasal cailage, D. Synovium
B: Muscles
Answer: B: Muscles 
Explanation: Muscles REF: Apley 8th edition page 77 Tophi are nodular deposition of crystals of mono sodium urate which get deposited in connective tissues like: Aicular cailage Tendon Synovium Aicular ends of bone Periaicular tissue Pinna Cailage Ligaments Kidney Subcutaneous tissue On X-ray: Tophi appears as punched out cysts with over hanging bony edges or G sign or mael's sign. Metatarsophalangeal joint is the most common and earliest joint affected by gout