This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Neuromuscular Blocker, Subject name: Anaesthesia
Which of the following muscle is blocked first by neuromuscular blocker:- 
Select and explain. 
A. Face, B. Proximal limb, C. Diaphragms and vocal cords, D. Distal limb
C: Diaphragms and vocal cords
Answer: C: Diaphragms and vocal cords 
Explanation: Neuromuscular blockade usually sooner occur at well perfused centrally located muscles (diaphragm or vocal cords ) than at peripheral locations (hand or foot). Recovery occurs also in same sequence thus diaphragm and vocal cords , face, proximal limbs and distal limbs. Sequence of NM paralysis and recovery from paralysis is sameDiaphragm & vocal cords - Head & Neck - Upper Limb - Trunk - Lower Limb