This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
The activity of procaine is terminated by: 
Select and explain. 
A. Elimination by kidney, B. Storage in the adipose tissue, C. Metabolism in the liver only, D. Metabolism in the liver and by pseudo-cholinesterase in the plasma
D: Metabolism in the liver and by pseudo-cholinesterase in the plasma
Answer: D: Metabolism in the liver and by pseudo-cholinesterase in the plasma 
Explanation: None