This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Oncology, Subject name: Medicine
Best treatment for glioblastoma multiforme: 
Select and explain. 
A. Chemotherapy, B. Radiation, C. Excision with radiation, D. Stereotactic surgery
C: Excision with radiation
Answer: C: Excision with radiation 
Explanation: Ans. C. Excision with radiation* These are highly infiltrative tumors, and the areas of increased T2/FLAIR signal surrounding the main tumor mass contain invading tumor cells.* Treatment involves maximal surgical resection followed by partial-field external beam radiotherapy (6000cGy in thirty 200-cGy fractions) with concomitant temozolomide, followed by 6-12 months of adjuvant temozolomide