This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
True about herpes simplex genitalis are all except: March 2012 
Select and explain. 
A. Caused due to herpes simplex virus, B. Risk of fetal infection is high at term, C. May lead to malignancy, D. Treated by acyclovir
C: May lead to malignancy
Answer: C: May lead to malignancy 
Explanation: Ans: C i.e. May lead to malignancy Herpes simplex genitalis From 70-90% of cases of herpes genitalis are caused by the herpes simplex virus (HSV), type 2 Risk of fetal infection is high in primary genital HSV at term due to high virus shedding compared to a recurrent infection Complications of herpes genitalis include sacral radiculopathy with urinary or fecal retention and aseptic meningitis (rare) Acyclovir 400 mg three times daily for 5 days is the drug of choice when viral culture is positive.