This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Pathology
Which of the following is not a major criteria for diagnosis of multiple myeloma ? 
Select and explain. 
A. Lytic bone lesions, B. Plasmacytoma on tissue biopsy, C. Bone marrow plasmacytosis > 30%, D. `M' spike > 3g% for 1g G, > 2g% for IgA
C: Bone marrow plasmacytosis > 30%
Answer: C: Bone marrow plasmacytosis > 30% 
Explanation: In the NCCN guidelines, active multiple myeloma is no longer diagnosed using the CRAB criteria (hyperCalcemia, Renal failure, Anemia, Bone lesions) for end-organ damage. The current diagnostic criteria are as follows : Bone marrow clonal plasma cells >=10% or bony or extramedullary plasmacytoma (confirmed by biopsy)