This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Apoptosis, Subject name: Pathology
Apoptosis is inhibited by? 
Select and explain. 
A. Bcl-2, B. Bax, C. Bad, D. P53
A: Bcl-2
Answer: A: Bcl-2 
Explanation: Ans. (a) Bcl-2Ref: Robbing pathology 9th ed. /53-54* Apoptosis is inhibited by anti-apoptosis genes which are mostly BCL family genes.# Example: BCL2, BCL-X, BCL-XL* Pro-apoptotic genes: they initiate and are involved in apoptosis.# Example: BAD, BIM, BAX, BAK* P53 is tumor suppressor gene and it causes apoptosis when there is excess of DNA damage which cannot be repaired