This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hemolytic anemia, Subject name: Pediatrics
All of the following are true of thalassemia major, EXCEPT: 
Select and explain. 
A. Splenomegaly, B. Target cells on peripheral smear, C. Microcytic hypochromic anemia, D. Increased osmotic fragility
D: Increased osmotic fragility
Answer: D: Increased osmotic fragility 
Explanation: - In thalassemia- decreased osmotic fragility is seen - Increased osmotic fragility is a feature of hereditary spherocytosis - Remaining all features given in the options are seen in thalassemia