This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pathology
A patient presents with endocrinopathy, fibrous dysplasia of bone and Hyperpigmentation. Diagnosis- 
Select and explain. 
A. McCune Albright syndrome, B. Addison's disease, C. Alagille syndrome, D. Lynch syndrome
A: McCune Albright syndrome
Answer: A: McCune Albright syndrome 
Explanation: Polyostotic fibrous dysplasia ,hyper pigmentation and endocrinopathies are the features of McCune-Albright syndrome. It clinically presents as precocious sexual development , most commonly in girls.other endocrinopathies like hypehyroidism,pituitary adenomas may also be seen. Bone lesions are often unilateral. Cutaneous macules are classically large ;dark to cafe-au-lait in color;with irregular serpiginous borders.McCune-Albright syndrome is caused by mutations in the GNAS gene. A small number, but not all, of the person's cells contain this faulty gene (mosaicism). (Ref:ROBBINS Text book of pathology)