This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Systemic Bacteriology Pa 1 (Gram Positive Cocci, Gram Negative Cocci), Subject name: Microbiology
All are true regarding staphylococcal toxin except - 
Select and explain. 
A. Beta haemolysin shows hot cold phenomenon, B. Mainly endotoxin, C. Enterotoxin causes food poisoning, D. Exfoliative toxin causes Ritters disease
B: Mainly endotoxin
Answer: B: Mainly endotoxin 
Explanation: Option 1 b Hemolysin: Sphingomyelinase Exhibits hot-cold phenomenon b Hemolysis is better seen at 37oC Option 2 Staphylococcus does not produce endotoxin. Endotoxin Produced by gram (-) ve organisms, the only gram (+) ve organism secreting endotoxin is listeria. Endotoxins are pa of the outer membrane of the cell wall of Gram-negative bacteria Option 3 Enterotoxins: Type A is responsible for most of the cases of food poisoning Option 4 Epidermolytic toxin (Exfoliative toxin) causes: 1. Scalded skin syndrome (Nikolsky's sign-epidermal layer separated) 2. Severe- Ritter disease (newborn), toxic epidermal necrolysis (TEN) (adult) 3. Milder- Pemphigus neonatorum, bullous impetigo