This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Disorders of Adrenal Gland, Subject name: Medicine
In a patient with pheochromocytoma, all of the following are seen except? 
Select and explain. 
A. Diarrhoea, B. Ohostatic hypotension, C. Episodic hypeension, D. Weight gain
D: Weight gain
Answer: D: Weight gain 
Explanation: Due to increased sympathomimetic stimulation, Pheochromocytoma has a weight loss. Phaeochromocytoma produces norepinephrine (80% cases) leading to hypeension but since the catecholamines act for sho duration and are released in bursts abnormally, the BP increases for some hours a day, which is referred to as Episodic hypeension. This catecholamine excess in future will lead to a persistent vasoconstriction, referred to as volume contracted state. This explains the Postural Hypotension/Ohostatic Hypotension Pheochromocytoma is a nasty tumor that can produce V.I.P and leads to Secretory diarrhea.