This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of nucleic acids, Subject name: Biochemistry
Termination is caused by all except 
Select and explain. 
A. Peptidyl transferase, B. 48s complex, C. RF-1, D. UAA
A: Peptidyl transferase
Answer: A: Peptidyl transferase 
Explanation: Termination Process of Translation After successive addition of amino acids , ribosome reaches the trerminator codon sequence (UAA ,UAG or UGA ) on the mRNA. Since , there is no tRNA bearing the corresponding anticodon sequence , the "A" site remains free. The release factor (RF) enters the site.The RF binds with rf3 NAD GTP. Theis complexalong hydrolyzes the peptide chain from the tRNA at the P site.This needs hydrolysis of GTP to GDP. The completed peptide chainis now released. Finally,80S ribosome dissociates into its component units of 60S and 40S. REF : DM VASUDEVAN TEXTBOOK , EIGHTH EDITION , Page no :583.