This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pharmacology
Which of the following statin has the longest Half Life 
Select and explain. 
A. Cerivastatin, B. Rosuvastatin, C. Atorvastatin, D. Simvastatin
B: Rosuvastatin
Answer: B: Rosuvastatin 
Explanation: Refer kDT 7/e 637 Rosuvastatin is primarily eliminated by excretion in the feces. The elimination half-lifeof rosuvastatin is approximately 19 hours.Rosuvastatin is not extensively metabolized; approximately 10% of a radiolabeled dose is recovered as metabolite. In contrast, the FDA suggests daytime administration for statins with longer half-lives (atorvastatin 14 hours, rosuvastatin 19 hours, and pravastatin 22 hours). Atorvastatin also has active metabolites withhalf-lives ranging from 20 to 30 hours, which may contribute to the fact that it can be taken at any time