This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Eye, Nose and Ear, Subject name: Anatomy
Failure of the choroid fissure to close results in 
Select and explain. 
A. Congenital detached retina, B. Congenital aniridia, C. Congenital aphakia, D. Coloboma iridis
D: Coloboma iridis
Answer: D: Coloboma iridis 
Explanation: Failure of the choroid (optic) fissure to close results in a cleft of the iris--called coloboma iridis (mostly in inferonasal position). This defect may extend into the ciliary body, choroid, optic nerve, or retina. Congenital aphakia--absence of the lens--may result from defective development of the lens placode.