This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Forensic Toxicology - Concepts, Statutes, Evidence, and Techniques, Subject name: Forensic Medicine
Maximum damage to the esophagus is caused by: 
Select and explain. 
A. Acid, B. Alkali, C. Organophosphate, D. Kerosene
B: Alkali
Answer: B: Alkali 
Explanation: Ans. (b) AlkaliRef.: The Essentials of FSM by K.S. Narayan Reddy 31st ed. / 499* Maximum damage to the esophagus is caused by ingestion of alkali as compared to acid.* Alkali causes Liquifactive necrosis which is more damaging than coagulative necrosis caused by acid.* Liquifactive necrosis is caused by hydrolytic enzymes. It attracts WBC which leads to bacterial infection and Pus formation. It can cause CNS ischemia also.* Acid causes coagulative necrosis due to coagulation of proteins. Coagulative necrosis is seen in all organs of body except brain.* MCC of coagulative necrosis is hypoxia.