This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
Which of the following is not seen in extraglandular Sjogren disease? 
Select and explain. 
A. Rheumatoid ahirits, B. Raynaud phenomenon, C. Lymphoma, D. Splenomegaly
D: Splenomegaly
Answer: D: Splenomegaly 
Explanation: Sjogren syndrome :*An autoimmune disease which targets exocrine glands*Most common glands which are affected are lacrimal glands and salivary glands causing keratoconjunctivitis sicca (dry eyes) and xerostomia (dry mouth).*Serology shows raised SS-A (Ro) and SS-B (La) antibodies*Autoantigens against which the antibodies are produced is alpha-fodrin (though not confirmed)*Extraglandular manifestations: Rheumatoid ahritis, Synovitis, diffuse pulmonary fibrosis, peripheral neuropathy, Raynaud phenomenon and marginal zone lymphoma. ( Ref: Robbins 8/e p221)