This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
All are used in treatment of amoebic liver abscess except - 
Select and explain. 
A. Diloxanide furoate, B. Chloroquine, C. Metronidazole, D. Emetine
A: Diloxanide furoate
Answer: A: Diloxanide furoate 
Explanation: Ans. is 'a' i.e., Diloxanide furoate Diloxanide furoate is a highly effective luminal amoebicide but has no systemic antiamoebic activity. This is because the furoate ester is hydrolysed in the intestine and the released diloxanide is absorbed. Diloxanide is a weaker amoebicide then its furoate ester and no systemic antiamoebic activity is seen despite its absorption.