This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Respiratory Chain, Subject name: Biochemistry
Uncoupler of oxidative phosphorylation - 
Select and explain. 
A. CN, B. CO, C. H2S, D. 2 DNP
D: 2 DNP
Answer: D: 2 DNP 
Explanation: Ans. is 'd' i.e., 2 DNP o As the name suggests, these componds block the coupeling of oxidation with phosphorylation. These compounds allow the transfer of reducing equivalents in respiratory chain but prevent the phosphorylation of ADP to ATP by uncoupling the linkage between ETC and phosphorylation. Thus the energy instead of being trapped by phosphorylation is dissipated as heat. Uncouplers may be:-i) NaturalThermogenin, thyroxineii) Synthetic2,4-dinitrophenol (2,4-DNP), 2,4-dinitrocresol (2,4-DNC), and CCCP (chlorocarbonylcyanidephenyl hydrazone).