This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Psychiatric Illness, Subject name: Pharmacology
True regarding bupropion is:- 
Select and explain. 
A. It is a dopamine reuptake inhibitor, B. It is an antianxiety drug, C. It does not precipitate seizures, D. It is a nicotinic receptor antagonist
A: It is a dopamine reuptake inhibitor
Answer: A: It is a dopamine reuptake inhibitor 
Explanation: Buspirone (5HT1A paial agonist) is anti-anxiety drug whereas bupropion is an anti-depressant drug. BUPROPION -- It is an atypical anti-depressant drug. -- It inhibits the uptake of NA and DA. -- More significant effect of bupropion is presynaptic release of catecholamines. -- It is metabolized to amphetamine like compound and possesses excitatory propey. -- It is used for smoking cessation as sustained release formulation. -- It can precipitate seizures at high dose.