This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Which of the following statements best describes the mechanism of action of benzodiazepines ? 
Select and explain. 
A. Benzodiazepines activate GABAB receptors in the spinal cord, B. Benzodiazepines block glutamate receptors in neuronal pathways in the brain, C. They increase the frequency of opening of chloride ion channels that are coupled to GABAA receptors, D. They are direct acting GABA receptor agonists in the CNS
C: They increase the frequency of opening of chloride ion channels that are coupled to GABAA receptors
Answer: C: They increase the frequency of opening of chloride ion channels that are coupled to GABAA receptors 
Explanation: None