This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Contra indication for DRE 
Select and explain. 
A. Acute anal fissure, B. Pilonidal sinus, C. Polyps, D. All of the above
A: Acute anal fissure
Answer: A: Acute anal fissure 
Explanation: Acute anal fissure is very painful, so DRE Is contraindicated.