This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology and breast, Subject name: Anatomy
Following condition has no increased risk of invasive breast carcinoma except 
Select and explain. 
A. Hyperplasia Atypical, B. Sclerosing Adenosis, C. Apocrine metaplagia, D. Duct ectasia
A: Hyperplasia Atypical
Answer: A: Hyperplasia Atypical 
Explanation: Cancer risk associated (with benign breast disorders and insitu carcinoma of the breast) Non-proliferative - no increased risk Sclerosing Adenosis - no increased risk Intra ductal papilloma--no increased risk Florid hyperplasia - 1.5 to 2 fold Atypical lobular hyperplasia - 4fold Atypical ductal hyperplasia - 4fold Ductal involvement by cells of Atypical ductal hyperplasia - 7 fold Lobular carcinoma insitu - 10fold Ductal carcinoma insitu- 10 fold Ref: Sabiston 20th edition Pgno :832