This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Central Nervous system, Subject name: Pharmacology
True statement about drugs used in Parkinsonism is: 
Select and explain. 
A. Amantadine is a cholinergic drug, B. Vitamin B6 enhances the L-Dopa action, C. COMT inhibitors prolong the action of L'-dopa, D. None
C: COMT inhibitors prolong the action of L'-dopa
Answer: C: COMT inhibitors prolong the action of L'-dopa 
Explanation: Both entacapone and tolcapone enhance and prolong the therapeutic effect of levodopa-carbidopa in advanced and fluctuating PD Ref KD Tripati 8th ed.