This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Other topics and Adverse effects, Subject name: Anatomy
All of the following statements about amlodipine are true except: 
Select and explain. 
A. It acts by conversion to an active metabolite in the liver, B. It has a very large volume of distribution, C. It undergoes very little first pass metabolism and possesses high and consistent oral bioavailability, D. It has a very long elimination half life
A: It acts by conversion to an active metabolite in the liver
Answer: A: It acts by conversion to an active metabolite in the liver 
Explanation: (Ref: KDT 6/e p531) Amlodipine is the longest acting DHP. It undergoes little first pass metabolism and is distributed widely. metabolites of amlodipine are inactive.