This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Medicine
Hallervorden-Spatz disease 
Select and explain. 
A. Is an iron storage disorder in brain, B. Most commonly occurs in adults, C. Relentlessly non progressive disease, D. Inherited as Autosomal dominant
A: Is an iron storage disorder in brain
Answer: A: Is an iron storage disorder in brain 
Explanation: It's a rare disorder characterized by progressive extrapyramidal dysfunction and dementiaA form of familial (inherited recessively-linked to chromosome 20) brain degeneration characterized by iron deposition in the brainA mutation in the pantothenate kinase gene has been describedMRI shows "eye-of-the-tiger sign"The disease is relentlessly progressive and the affected individuals typically die in 2nd or 3rd decade(ref:Harrison 18th /e p2251)