This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Protein Synthesis Inhibitors, Subject name: Pharmacology
What is the most serious adverse effect of streptomycin? 
Select and explain. 
A. Hepatotoxicity, B. Ototoxicity, C. Ocular toxicity, D. Hematological disturbances
B: Ototoxicity
Answer: B: Ototoxicity 
Explanation: Streptomycin (S) This is a tuberculocidal aminoglycoside. It is not absorbed orally and must be administered by IM injection. It is active only against extra-cellular bacteria. It is NOT HEPATOTOXIC. Major adverse effects are ototoxicity, nephrotoxicity and neuromuscular blockade. Streptomycin is contraindicated in PREGNANCY.