This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Pathology
Gp deficiency is seen in - 
Select and explain. 
A. Glanzmann's thrombasthenia, B. Bemard-Soulier syndrome, C. Platelet storage pool disorders, D. GPillb
A: Glanzmann's thrombasthenia
Answer: A: Glanzmann's thrombasthenia 
Explanation: Answer is option 1 Glanzmann's thrombasthenia is an abnormality of the platelets. It is an extremely rare coagulopathy (bleeding disorder due to a blood abnormality), in which the platelets contain defective or low levels of glycoprotein IIb/IIIa (GpIIb/IIIa), which is a receptor for fibrinogen. As a result, no fibrinogen bridging of platelets to other platelets can occur, and the bleeding time is significantly prolonged. Ref Robbins 9/e pg 450