This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Which of the following is TRUE about papillary carcinoma of thyroid? 
Select and explain. 
A. Cells have intranuclear vacuolation, B. Amyloid deposition are seen, C. Encapsulated, D. Comprises 10-15% of all thyroid cancer
C: Encapsulated
Answer: C: Encapsulated 
Explanation: Papillary carcinoma thyroid is most common of all thyroid cancers and it comprises about 85% of all thyroid cancers. Amyloid deposition is the feature of medullary carcinoma thyroid, not of papillary carcinoma. Cells in papillary carcinoma thyroid shows Orphan eye nuclei. "Papillary carcinomas are solitary or multifocal lesions. Some tumors may be well circumscribed and even capsulated; other may infiltrate the adjacent parenchyma with ill defined margins". Ref: Robbins 8/e, page 1121.