This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Integrated QBank, Subject name: Unknown
A 4 yr. old boy was brought by his mother to the OPD regarding complaints of cola coloured urine for 8 days. The mother has noticed repeated attacks earlier too. Associated history reveals SNHL and slit lamp examination reveals All of the statements regarding the disease are true EXCEPT? 
Select and explain. 
A. It is caused due to Defect in alpha 3 chain of Type IV collagen, B. Bilateral anterior lenticonus can be seen in this condition, C. Electron microscopy of the kidney specimen reveals thinning of GBM and basket weave appearance., D. The mode of inheritance is X linked
A: It is caused due to Defect in alpha 3 chain of Type IV collagen
Answer: A: It is caused due to Defect in alpha 3 chain of Type IV collagen 
Explanation: Presence of haematuria with SNHL with anterior lenticonus as shown in the slit lamp suggests the diagnosis of Alpo's syndrome. Alpo's syndrome is and X linked disorder characterized by defect in alpha 5 chain of type IV collagen. Electron microscopy reveals thinning of basement membrane (<150nm) as the earliest feature and 'basket weave appearance' is characteristic on EM.