This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
All are true regarding blood supply increase in muscle during exercise except 
Select and explain. 
A. Local metabolite, B. Sympathetic stimulation, C. Cholinergic stimulation, D. Inhibition of beta receptor
D: Inhibition of beta receptor
Answer: D: Inhibition of beta receptor 
Explanation: Ans. D. Inhibition of beta receptor.CHANGES IN MUSCLE BLOOD FLOW DURING EXERCISEThe blood flow of resting skeletal muscle is low (2-4 ml./100 g/min). The muscle blood flow can increase a maximum of about 25 fold during the most strenuous exercise.Amount of blood flow to skeletal muscles during exercise : 50 to 75 mL/min of blood per 100 g of muscle.Dilation of aerioles in skeletal muscles due to cholinergic sympathetic nerve activity and stimulation of beta-adrenergic receptors by the hormone epinephrine leads to increased blood supply.The local mechanisms maintaining a high blood flow in exercising muscle include a fall in tissue P02, a rise in tissue PCO2, and accumulation of K+, and other vasodilator metabolites. The rise in temperature fuher dilates the vessels.