This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Psychiatry
In a child of Rett syndrome, all of the following are seen except: 
Select and explain. 
A. Macrocephaly, B. Mental retardation, C. Abnormal dendritic connections, D. Seizures
A: Macrocephaly
Answer: A: Macrocephaly 
Explanation: Ans. a. Macrocephaly Microcephaly, not the macrocephaly is seen in Rett syndrome.Rett SyndromeRett syndrome, originally termed as cerebroatrophic hyperammonemiaA neurodevelopmental disorder of the grey matter of the brainExclusively affects femalesCause:Caused by mutations in the gene MECP2 located on the X chromosomeClinical Features:Small hands and feetDeceleration of the rate of head growth (microcephaly)Repetitive stereotyped hand movements, such as wringing and/or repeatedlyUp to 80% have seizuresNo verbal skillsDelayed or absent ability to walkScoliosis, growth failure, and constipation are very common