This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Virology, Subject name: Microbiology
Active replication in Hepatitis B infection is indicated by ? 
Select and explain. 
A. HBeAg, B. HBsAg, C. HBcAg, D. Anti-HBsAg
A: HBeAg
Answer: A: HBeAg 
Explanation: Circulating HBeAg is an indicator of active intra hepatic viral replication REF:ANANTHANARYANAN TEXT BOOK OF MICROBIOLOGY 9EDITION PGNO.547