This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Medicine
Crescent formation is characteristic of the following glomerular disease - 
Select and explain. 
A. Minimal change disease, B. Rapidly progressive glomerulonephritis, C. Focal and segmental glomerulonephritis, D. Rapidly non progressive glomerulonephritis
B: Rapidly progressive glomerulonephritis
Answer: B: Rapidly progressive glomerulonephritis 
Explanation: Rapidly progressive glomerulonephritis (RPGN) is characterised by rapid loss of renal function over days to weeks, usually in association with hypeension and oedema. Non-visible haematuria is almost always present with variable amounts of proteinuria, while characteristic red cell casts and dysmorphic red cells may be observed on urine microscopy . Renal biopsy typically shows crescentic lesions , often associated with necrotising lesions within the glomerulus , paicularly in small-vessel vasculitides. This pattern of presentation is typical of post-infectious glomerulonephritis, anti-GBM disease and small-vessel vasculitides It can also be observed in SLE and occasionally in IgA and other nephropathies . Ref Harrison20th edition pg 292