This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Deficiency in globin synthesis 
Select and explain. 
A. Thalassemia, B. Sickle cell disease, C. Hereditary spherocytosis, D. None of these
A: Thalassemia
Answer: A: Thalassemia 
Explanation: Ans. is 'a' i.e., ThalassemiaThalassemia Syndromes :?The thalassemia syndromes are a heterogeneous group of disorders caused by inherited mutations that decrease the synthesis of either the a-globin or (3-globin chains that compose adult hemoglobin, HbA (a2(32), leading to anemia, tissue hypoxia, and red cell hemolysis related to the imbalance in globin chain synthesis.