This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Which of the following organelles plays a pivotal role in Apoptosis: 
Select and explain. 
A. Mitochondria, B. Endoplasmic Reticulum, C. Nucleus, D. Golgi Apparatus
A: Mitochondria
Answer: A: Mitochondria 
Explanation: Initiation of apoptosis occurs through two different pathways, intrinsic mitochondria pathway and extrinsic death receptor mediated pathway. Mitochondria plays active role in apoptosis. Ref: Tanley L. Robbins, Ramzi S. Cotran, (2012) , Chapter 1, "Cell Injury", In the book, "Pocket Companion to Robbins and Cotran Pathologic Basis of Disease", 8th Edition, USA, Page 27; Robbin's Basic Pathology, 7th Edition, Pages 28, 29; Essential of Apoptosis (2003), Page 245