This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Most common manifestation of clostridium difficile infection is: 
Select and explain. 
A. Fever, B. Leukocytosis, C. Abdominal pain, D. Diarrhea
D: Diarrhea
Answer: D: Diarrhea 
Explanation: Most common manifestation of clostridium difficile infection is Diarrhea Stool is soft, watery or mucoid in consistency, with a characteristic odor with 20 bowel movements per day. Other features: Fever in 28% Abdominal pain in 22%, Leukocytosis in 50% Unexplained leukocytosis, with 15,000 white blood cells (WBCs)/L may indicate c. difficile infection. Complications: 1. Toxic megacolon and sepsis. Ref: Harrison, Edition-18, page-1092.