This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Ophthalmology
Knudson's hypothesis is applied for: 
Select and explain. 
A. Glaucoma, B. Retinoblastoma, C. Cataract, D. Melanoma
B: Retinoblastoma
Answer: B: Retinoblastoma 
Explanation: Ans. Retinoblastoma