This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrine System, Subject name: Physiology
Which of the following hormone have a GENOMIC action? 
Select and explain. 
A. Thyroid hormone, B. 1,25 DHCC, C. Coisol, D. All of these
D: All of these
Answer: D: All of these 
Explanation: Several hormones, including adrenal and gonadal steroid hormones, thyroid hormones, retinoid hormones, and vitamin D, bind with protein receptors inside the cell rather than in the cell membrane. Because these hormones are lipid soluble, they readily cross the cell membrane and interact with receptors in the cytoplasm or nucleus. The activated hormone-receptor complex then binds with a specific regulatory (promoter) sequence of the DNA called the hormone response element, and in this manner either activates or represses transcription of specific genes and formation of messenger RNA.