This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pharmacology
Wof is a limiting adverse effect of ACE inhibitors 
Select and explain. 
A. Acidosis, B. Hypernatremia, C. Hypokalemia, D. Hyperkalemia
D: Hyperkalemia
Answer: D: Hyperkalemia 
Explanation: Adverse effects:- By reducing aldosterone levels, ACE inhibitors decrease K + excretion in the distal nephron leading to hyperkalemia. Hyperkalaemia: more likely in patients with impaired renal function and in those taking K+ sparing diuretics, NSAIDs. Ref:- kd tripathi; pg num:-495,502