This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Parathyroids, Subject name: Pathology
A female neonate with DiGeorge syndrome develops severe muscle cramps and convulsions soon after bih. Which of the following is the cause of convulsions in this neonate? 
Select and explain. 
A. Acute hemorrhagic adrenalitis, B. Hypocalcemia, C. Hypoglycemia, D. Hypokalemia
B: Hypocalcemia
Answer: B: Hypocalcemia 
Explanation: DiGeorge syndrome: - Caused by failure in development of 3rd and 4th branchial pouches, resulting in Agenesis/ hypoplasia of thymus & parathyroid glands Congenital hea defects Dysmorphic facies -Occurs secondary to deletions on chromosome 22q11.2 - As a result of parathyroid agenesis, patients with DiGeorge syndrome exhibit hypocalcemia, which manifests as increased neuromuscular excitability. - Symptoms range from mild tingling in hands & feet to severe muscle cramps & convulsions.