This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Respiratory system, Subject name: Anatomy
A 60 year old man is suspected of having endobronchial carcinoma: what should be the best investigation 
Select and explain. 
A. CT guided FNAC, B. bronchoscopy and biopsy, C. Sputum cytology, D. X-ray chest
B: bronchoscopy and biopsy
Answer: B: bronchoscopy and biopsy 
Explanation: Fibreoptic bronchoscopy and biopsy is the investigation of choice in patients suspected endobronchogenic carcinoma,as endobronchial lesions are not reliably visualised on CT Ref Harrison 19th edition pg 246,247,512