This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Antenatal Screening, Subject name: Gynaecology & Obstetrics
A mother with 10 wks pregnancy and who had previously baby with open neural tube defect which statement is true - 
Select and explain. 
A. Sodium valproate causes open neural tube defect., B. Risk of recurrence is 10%, C. Aminocentesis should be done, D. Give multivitamin.
A: Sodium valproate causes open neural tube defect.
Answer: A: Sodium valproate causes open neural tube defect. 
Explanation: Ans. is 'a' i.e. Sodium valproate causes open neural tube defect.Sodium valproate causes neural tube defect when given to pregnant ladies.Folic acid supplementation is given to prevent neural tube defect (not multivitamins).Risk of recurrence of neural tube defect is 5%* (not 10%).Amniocentesis is used to diagnose neural tube defects but the ideal time is 14-16 wks*.