This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Which of the following is not the source of cytosolic NADPH ? 
Select and explain. 
A. Isocitrate dehydrogenase, B. ATP citrate lyase, C. Malic enzyme, D. G6PD
B: ATP citrate lyase
Answer: B: ATP citrate lyase 
Explanation: Answer. B. ATP citrate lyaseNADPH is a cofactor used in anabolic reactions, such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent.The major source of NADPH in animals and other non-photosynthetic organisms is the pentose phosphate pathway.The key enzymes in these processes are: NADP-linked malic enzyme, NADP-linked isocitrate dehydrogenase, NADP-linked glutamate dehydrogenase and nicotinamide nucleotide transhydrogenase.