This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Uterine fibroid, Subject name: Gynaecology & Obstetrics
Decreased vascularity of fibroid is seen with 
Select and explain. 
A. GnRH agonist, B. Danazol, C. Mifepristone, D. Clomiphene citrate
A: GnRH agonist
Answer: A: GnRH agonist 
Explanation: GnRH analogues used for 6months reduce the size by 50-80%. It is also useful in reducing the vascularity besides size preoperatively and thus causing amenorrhoea which restores hb level. Ref:shaw's textbook of gynaecology;15th edition; Pg :359