This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Anaesthesia
Among the following local anaesthetics, the one that is associated with vasoconstriction and mydriasis is : 
Select and explain. 
A. Cocaine, B. Bupivacaine, C. Procaine, D. Lignocaine
A: Cocaine
Answer: A: Cocaine 
Explanation: Local application of cocaine causes blockage of initiation and conduction of nerve impulses. It also blocks neuronal re uptake of nor epinephrine thus potentiating adrenergic activity. Ocular effects of cocaine includes anaesthesia, mydriasis and vasoconstriction. Mydriatic effect of cocaine depends upon presence of a functioning adrenergic innervation. Procaine causes vasodilation hence it is usually given with adrenaline. The main shocomings of procaine are: Being a vasodilator, when it is given in the absence of a vasoconstrictor agent procaine is rapidly absorbed into the circulation and hydrolysed by plasma cholinesterase. Hypersensitivity to procaine is commonly encountered. Ref: Clinical Ocular Pharmacology edited by Jimmy D. page 119. Principles of Pharmacology: A Tropical Approach By D. T. Okpako page 403.