This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
Memory cell in immune system are long lived and escape apoptosis because of: 
Select and explain. 
A. Insulin like growth factor, B. Fibroblast growth factor (FGF), C. Platelet derived growth factor, D. Nerve growth factor
D: Nerve growth factor
Answer: D: Nerve growth factor 
Explanation: D i.e. Nerve growth factorNerve growth factor inhibits apoptosis in memory B cellsQ inactivation of p38 MAPK, prevention of antiapoptotic factor Bcl-2 phosphorylation (i.e. maintaining its integrity) & cytochrome c releaseAlthough other growth factors like FGF, PDGF and IGF can also prolong the survival, it is the nerve growth factor that is most impoant in immoalization of memory cells.Growth factor --> activate P13 kinase --> activate Akt --> inactivates procaspase 9 & inhibit Fast synthesis