This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Central Nervous system, Subject name: Pharmacology
Which of the following abolishes the therapeutic effect of levodopa: 
Select and explain. 
A. Thiamine, B. Carbidopa, C. Pyridoxine, D. Benserazide
C: Pyridoxine
Answer: C: Pyridoxine 
Explanation: Pyridoxine abolishes therapeutic effect of levodopa by enhancing peripheral decarboxylation of levodopa, less is available to cross to the brain. Ref KD Tripathi 8th ed.