This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Prolonged use of aspirin causes: 
Select and explain. 
A. Hypoprothrombinemia, B. Hyperprothrombinemia, C. Hypophosphatasia, D. Hypercalcemia
A: Hypoprothrombinemia
Answer: A: Hypoprothrombinemia 
Explanation: None