This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
A five year old boy presents with precocious pubey and a blood pressure of 130/80 mmHg. Estimation of which of the following will help in diagnosis ? 
Select and explain. 
A. | 17 hydroxy-progesterone, B. | Coisol, C. | Aldosterone, D. | 11 deoxycoisol
D: | 11 deoxycoisol
Answer: D: | 11 deoxycoisol 
Explanation: Ans. is `d' i.e. | 11 deoxycoisol o At the age of 5-6 years, BP in excess of 115/75 mm Hg is considered as hypeesion (This boy has BP 130/80). o So, the boy in this question has : ? i) Precocious pubey ii) Hypeension o Precocious pubey in male, with salt retention and hypeension, occurs due to deficiency of 11-13 Hydroxylase which catalyzes the conversion of 11 deoxycoisol to coisol.