This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Which of the following interacts with Digitalis maximally- 
Select and explain. 
A. Furosemide, B. Triamterene, C. Amiloride, D. Spironolactone
A: Furosemide
Answer: A: Furosemide 
Explanation: Ans. is 'a' i.e., Furosemide o Two classes of diuretics are given in the options Loop Diuretics -----> Furosemide (cause hypokalemia) Potassium sparing diuretics ----> Spironolactone, Trimetrene, Amiloride (cause Hyperkalemia) We know that digitalis toxicity is potentiated by hypokalemia. So the drug interacting with digitalis will be Furosemide as it causes Hypokalemia.