This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.V.S, Subject name: Pharmacology
Digoxin is not indicated in: 
Select and explain. 
A. Atrial flutter, B. Atrial fibrillation, C. High output failure, D. PSVT
C: High output failure
Answer: C: High output failure 
Explanation: Ans. (C) High output failure(Ref: KDT 8th/e p560, 561)Digitalis is an inotropic agent that is indicated when heart is not able to pump the blood adequately. High output failure is seen in conditions like anemia and thyrotoxicosis in which heart is already contracting vigorously. Cardiac glycosides, thus are not indicated in high output failure.