This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Acanthosis nigricans can occurs due to ? 
Select and explain. 
A. Increased multiplication of basal cells, B. Comification of basal cells, C. Keratinisation of epidermal cells, D. All
C: Keratinisation of epidermal cells
Answer: C: Keratinisation of epidermal cells 
Explanation: Ans. is 'c' i.e., Keratinization of epidermal cellsHistological features of Acanthosis nigricanso Hyperplasia of stratum spinosum of the epidermis.o Hyperkeratosis ---> Thickening of Stratum corneum of epidermis (Cornification of epidermis).Slight basal cell hyperpigmentation