This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Physiology
Half-life of insulin is 
Select and explain. 
A. 1-2 min, B. 4-6 min, C. 10-12 min, D. 12-16 min
B: 4-6 min
Answer: B: 4-6 min 
Explanation: The half-life of insulin in the circulation in humans is about 5 min. Insulin binds to insulin receptors, and some are internalized. It is destroyed by proteases in the endosomes formed by the endocytotic process.Ref: Ganong's, Review of Medical Physiology, Twenty-Third Edition, Page number: 318