This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Primary Open-Angle Glaucoma and Related Conditions, Subject name: Ophthalmology
Uveoscleral outflow is increased by - 
Select and explain. 
A. Timolol, B. Bimatoprost, C. Mannitol, D. Dorzolamide
B: Bimatoprost
Answer: B: Bimatoprost 
Explanation: Ans. is 'b' i.e., Bimatoprost Mechanism of action of pharmacological agents in POAGAgentMechanism of actiono b-blocker (Timolol, Betaxolol, levobunolol, carteolol)o Prostaglandins (latanoprost, bimatoprost, travoprost)o Alpha agonists# Non-selective (Epinephrine, Dipivefrine)# Selective a-2 (Aproclonidine, Brimonidine)o Carbonic anhydrase inhibitors (Dorzolamide, Brinzolamide, Acetazolamide)o Cholinomimetics (Pilocarpine, physostigmine, carbachol, echothiphate)o Hyperosmotic agents (Mannitol, glycerol)o Decreased aqueous secretion from ciliary epitheliumo Increased uveoscleral aqueous outflowIncreased uveoscleral aqueous outflowDecreased aqueous secretiono Decreased aqueous secretion due to lack of HCO3-o Increased aqueous outflow due to opening of trabecular meshwork due to ciliary muscle contractiono Reduce vitreous volume and deepen anterior chamber