This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Breast, Subject name: Surgery
Which of the following breast lesions are noninvasive malignancies? 
Select and explain. 
A. Intraductal carcinoma of the comedo type, B. Tubular carcinoma and mucinous carcinoma, C. Infiltrating ductal carcinoma and lobular carcinoma, D. Medullary carcinoma, including atypical medullary lesions
A: Intraductal carcinoma of the comedo type
Answer: A: Intraductal carcinoma of the comedo type 
Explanation: Intraductal carcinoma refers to a malignancy of ductal origin that remains enclosed within duct structures. This noninvasive proliferation can undergo central necrosis, which frequently calcifies to form the microcalcifications seen on mammography Tubular, mucinous, and medullary carcinomas are histologic variants of infiltrating ductal cancer and are all invasive malignancies. Infiltrating lobular cancer is a paicular histologic variant of invasive breast cancer characterized by permeation of the stroma with small cells that resemble those found in the breast lobule or acinus.