This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Microbiology
BRAF V600E mutations are seen in all of the following Except 
Select and explain. 
A. Langherhan's cell histiocytosis, B. Erdheim Chester disease, C. Ovarian carcinoma, D. Grade II astrocytoma
D: Grade II astrocytoma
Answer: D: Grade II astrocytoma 
Explanation: BRAF V600E (valine conveing to glutamate at the 600th position)is seen in the following cancers:Langerhan's cell histiocytosisHairy cell leukemiaMalignant melanomaPilocytic astrocytoma (WHO Grade I astrocytoma)Ovarian carcinomaEndometrial carcinomaColorectal carcinomaPapillary carcinoma thyroidErdheim Chester disease