This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Pathology
Sickle cell disease associated with which type of renal cell carcinoma? 
Select and explain. 
A. Medullary, B. Papillary, C. Chromophobe, D. Colloid
A: Medullary
Answer: A: Medullary 
Explanation: A i.e. MedullaryRef: WHO, Urogential System, page 122Explanation:Medullary Renal Cell CarcinomaRare, highly aggressive medulla centered carcinoma.Associated with sickle cell trait* or other hemoglobinopathies*.Rare carcinoma arising in the renal medulla.Occurs predominately in young patients with sickle cell trait.Variety of histologic patterns.Sickied erythrocytes may be pathognomonic.Majority show loss of SMARCB1 /INI1*.Poor prognosis*.