This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Which is not a pa of Kaageners syndrome:March 2007 
Select and explain. 
A. Situs inversus, B. Chronic sinusitis, C. Bronchiectasis, D. Cardiomegaly
D: Cardiomegaly
Answer: D: Cardiomegaly 
Explanation: Ans. D: CardiomegalyPrimary ciliary dyskinesia/PCD/immotile ciliary syndrome/ Kaagener Syndrome is a rare autosomal recessive genetic disorder which causes a defect in the action of the cilia lining the respiratory tract (lower and upper, sinuses, Eustachian tube, middle ear) and fallopian tube.PCD is a genetically heterogenous disorder affecting motile cilia.Around 90% of individuals have ultrastructural defects affecting protein(s) in the outer and/or inner dynein arms which give cilia their motilityWhen accompanied by the combination of situs inversus (reversal of the internal organs), chronic sinusitis, and bronchiectasis, it is known as Kaagener syndrome.The main consequence of impaired ciliary function is reduced or absent mucus clearance from the lungs, and susceptibility to chronic recurrent respiratory infections, including sinusitis, bronchitis, pneumonia, and otitis media. Infeility is common, due to defective ciliary action in the follopian tube in affected females or diminished sperm motility in affected males.