This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Complement system, Subject name: Pathology
Complement responsible for activation of bacterial lysis is: 
Select and explain. 
A. C3a, B. C3b, C. C5-9, D. C5a
C: C5-9
Answer: C: C5-9 
Explanation: Membrane attack complex is responsible for cell lysis It consist of C-5,6,7,8,9 complement proteins. This MAC get deposited on the cell membrane, and drills holes into it Thus, Cell become premeable to water and ions, leading to osmotic death (lysis)