This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
True about Dezocine - 
Select and explain. 
A. Slower acting than morphine, B. Less potent than morphine, C. Acts GABA, D. Doesn't increase histamine release
D: Doesn't increase histamine release
Answer: D: Doesn't increase histamine release 
Explanation: Ans. is 'd' i.e., Doesn't increase histamine release Dezocine Dezocine is an opioid agonist-antagonist. o Its analgesic potency, onset and duration of action in the relief of postoperative pain are comparable to morphine. o It has no effect on histamine and catecholamines secretion. o Like other agonist-antagonist it exhibits ceiling effect for respiratory depression. It has a high affinity for receptors and moderate affinity for 8 receptors.