This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Regional anaesthesia, Subject name: Anaesthesia
Local anaesthesia causing methemoglobineinia - 
Select and explain. 
A. Procaine, B. Prilocaine, C. Etodicaine, D. Ropivacaine
B: Prilocaine
Answer: B: Prilocaine 
Explanation: O-toludine metabolites of prilocaine accumulate after large dose of drug conve hemoglobin to methemoglobin lead to methemoglobulinemia, dose depndent(range of 10mg/kg) Treatment of methemoglobinemia is IV methylene blue Benzocaine also cause methemoglobinemia