This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Salivary Glands, Subject name: Surgery
Amifostine protects all of the following except: 
Select and explain. 
A. CNS, B. Kidneys, C. Salivary glands, D. GIT
A: CNS
Answer: A: CNS 
Explanation: Amifostine It is a prodrug that is dephosphorylated by alkaline phosphatase in tissues to a pharmacologically active free thiol metabolite Cause reduction of the cumulative renal toxicity of cisplatin and toxic effects of radiation on normal oral tissues Amifostine protects -Kidneys - Salivary glands - GIT