This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetics And Genetic Disorders, Subject name: Pediatrics
Following are potential complications of gene therapy except: 
Select and explain. 
A. Genotoxicity, B. Genome integration, C. Gene silencing, D. Immunotoxicity
B: Genome integration
Answer: B: Genome integration 
Explanation: b. Genome integration(Ref: Nelson's 20/e p 584-586)Problems with gene therapy especially with viral vectors include toxicity, immune and inflammatory responses.