This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti-HIV Drugs, Subject name: Pharmacology
Eirenz limits HIV infection by: 
Select and explain. 
A. Binding to active site of HIV reverse transcriptase, B. Impairing the binding of HIV virion to CD4 receptors on T- cells, C. Inhibiting the HIV protease, D. Serving as an allosteric inhibitor of HIV reverse transcriptase
D: Serving as an allosteric inhibitor of HIV reverse transcriptase
Answer: D: Serving as an allosteric inhibitor of HIV reverse transcriptase 
Explanation: Eirenz is a NNI which acts as an allosteric (non-competitive) inhibitor of HIV reverse transcriptase. It is more potent than zidovudine on HIV-1, but do not inhibit HIV-2. If used alone, viral resistance develops rapidly by point mutation of the enzyme; therefore it should always be combined with 2 other effective drugs. S/E of Eirenz : Headache, rashes, dizziness, insomnia, neuro-psychiatric symptoms