This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Drug induced lupus antibodies are found in ? 
Select and explain. 
A. Anti-Rho, B. Ds-DNA, C. Anti-Sm, D. Anti-histone antibody
D: Anti-histone antibody
Answer: D: Anti-histone antibody 
Explanation: Ans. is 'd' i.e., Anti Histone antibody Drug induced lupus ervthematosus o A lupus like syndrome may develop in patients receiving a variety of drugs. o Procainamide and hydralazine are most common offenders. o Most patients do not have symptoms of lupus erythematosus. o Anti ds DNA antibody is rare There is an extremely high frequency of antihistone antibodies. o Although multiple organs may be affected renal and CNS involvement, usually does not occur.