This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Other topics and Adverse effects, Subject name: Anatomy
Which of the following drugs is most likely to cause loss of equilibrium and auditory change 
Select and explain. 
A. Amikacin, B. Ethambutol, C. Isoniazide, D. Rifabutin
A: Amikacin
Answer: A: Amikacin 
Explanation: Ref-KDT 6/e p721 Aminogycosides can cause nephrotoxicity, ototoxicity and neuromascular block