This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Skin
What is the percentage of patients with disseminated discoid lupus erythematosus who develop SLE? 
Select and explain. 
A. 2%, B. 22%, C. 52%, D. 82%
B: 22%
Answer: B: 22% 
Explanation: The risk is higher in patients with disseminated DLE (22%) than in DLE confined to the head and neck (1.2%). Females developing DLE before the age of 40 years,with HLA-B8 in their histocompatibility type, have an increasedrisk of 'conveing' to SLE. Neither immunological nor biochemical abnormalities appear to alter the patient's progress. Note: Carpet tack/tin tack sign is positive in DLE lesions. Ref: Rook's textbook of dermatology, Edition-8, Page 51.20.