This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Pheochromocytoma is usually associated with:September 2007 
Select and explain. 
A. Pancreatic exocrine carcinoma, B. Astrocytoma, C. Neurofibromatosis, D. Neuroblastoma
C: Neurofibromatosis
Answer: C: Neurofibromatosis 
Explanation: Ans. C: NeurofibromatosisPheochromocytoma linked to MEN II ca be caused by RET oncogene mutations. Both syndromes are characterized by pheochromocytoma as well as thyroid cancer (thyroid medullary carcinoma). MEN IIA also presents with hyperparathyroidism, while MEN IIB also presents with mucosal neuroma.Pheochromocytoma is also associated with neurofibromatosis