This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.V.S, Subject name: Medicine
All the following statements about mitral valve prolapse are true except 
Select and explain. 
A. It is more common in females, B. Most patients are symptomatic, C. It has a benign clinical course, D. Transient cerebral ischemic is a know complication
B: Most patients are symptomatic
Answer: B: Most patients are symptomatic 
Explanation: Ref Harrison 19 th ed pg 1546 Most patients are asymptomatic and remain so for their entire lives. However, in Noh America, MVP is now the most common cause of isolated severe MR requiring surgical treatment.