This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
Tumor Suppressor Gene associated with Familial gastric cancer and Lobular breast carcinoma is 
Select and explain. 
A. RB, B. PTEN, C. APC, D. CDH1
D: CDH1
Answer: D: CDH1 
Explanation: GeneProteinFunctionFamilial syndromesSporadic CancersCDH1E-cadherinCell adhesion,inhibition of cell motilityFamilial gastric cancerGastric carcinoma, Lobular breast carcinomaRef: Robbins and Cotran Pathologic Basis of Disease; 9th edition; Chapter 7; Neoplasia; Page no: 291; Table: 7-7