This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Autonomic nervous system, Subject name: Pharmacology
Beta blocker without local anaesthetic effect is: 
Select and explain. 
A. Metoprolol, B. Pindolol, C. Propanolol, D. Timolol
D: Timolol
Answer: D: Timolol 
Explanation: Essentials of medical pharmacology Seventh edition, KD Tripathi Page no=153 Timolol is the prototype of ocular beta-blockers. Is non-selective and has no local anaesthetic or intrinsic sympathomimetic activity.