This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
DOC in Wilson disease with Neurologic/Psychiatric manifestation is: 
Select and explain. 
A. Trientine and Zinc, B. Zinc alone, C. Tetrathiomolybdate and zinc, D. d-Penicillamine alone
C: Tetrathiomolybdate and zinc
Answer: C: Tetrathiomolybdate and zinc 
Explanation: Wilson disease treatment: Condition DOC Hepatitis or cirrhosis without decompensation: Zinc Cirrhosis with decompensation: Trientine and Zinc Mild - Trientine and Zinc Moderate - Hepatic transplantation Severe - Hepatic transplantation ALSO NOTE: In patients with neurologic and psychiatric illness due to wilson the initial treatment of choice is Tetrathiomolybdatec and zinc Ref: Harrison, E-18, P-3190.