This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Breast, Subject name: Pathology
ER positive status in Ca Breast indicates 
Select and explain. 
A. Prognosis, B. Etiology, C. Site, D. None
A: Prognosis
Answer: A: Prognosis 
Explanation: The presence or absence of estrogen or progesterone receptors ; The presence of hormone receptors confers a slightly better prognosis. However, the practical reason for determining their presence is to predict the response to therapy. The highest rate of response (approximately 80%) to antiestrogen therapy (oophorectomy or tamoxifen) is seen in women whose tumor cells express both estrogen and progesterone receptors ref : Robbins Basic Pathology, 9E,page-713