This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
A major source of collagen in cirrhosis - 
Select and explain. 
A. Kupffer cells, B. Ito cell (Hepatic stellate cell), C. Hepatocyte, D. Canalicular cell
B: Ito cell (Hepatic stellate cell)
Answer: B: Ito cell (Hepatic stellate cell) 
Explanation: Perisinusoidal stellate cells (Ito cells) play a role in the storage and metabolism of vitamin A and are transformed into collegen producing myofibroblasts when there is inflamation of the liver.
These cells are the major source of collagen in cirrhosis