This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Role of neo-adjuvant chemotherapy in breast carcinoma patient is: March 2011 
Select and explain. 
A. Curing distant metastasis, B. To shrink the tumour to enable breast conserving therapy, C. Limiting metastasis, D. Symptomatic
B: To shrink the tumour to enable breast conserving therapy
Answer: B: To shrink the tumour to enable breast conserving therapy 
Explanation: Ans. B: To shrink the tumour to enable breast conserving therapy Primary chemotherapy (neoadjuvant) is being used in many centres for large but operable tumours that would traditional require a mastectomy (and almost ceainly postoperative adjuvant chemotherapy) The aim of this treatment is to shrink the tumour to enable breast conserving surgery to be performed