This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Organ most vulnerable to ischaemic due to shock? 
Select and explain. 
A. Lungs, B. Adrenals, C. Kidney, D. Hea
D: Hea
Answer: D: Hea 
Explanation: Ans. is 'd' i.e., Hea o The susceptibility of a tissue to hypoxia influences the likelihood of infarction. o Neurons are most sensitive to hypoxia (irreversible changes develop in 3-4 minutes) followed by myocardial cells (irrversible changes develop in 20-40 minutes). o Fibroblasts are amongst the most resistent cells to hypoxia.