This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
A 29-year-old person comes with focal seizures. MRI shows frontal and temporal enhancement. What is the most probable diagnosis? 
Select and explain. 
A. Meningococcal meningitis, B. Herpes simplex encephalitis, C. Japanese encephalitis, D. Enterovirus encephalitis
B: Herpes simplex encephalitis
Answer: B: Herpes simplex encephalitis 
Explanation: §In children and young adults primary HSV infection can led to encephalitis, by neurotropic spread of virus from periphery via olfactory bulb.
§In other majority of cases, there is prior mucocutaneous HSV-1 infection which gets reactivated.
§Clincial hallmark of HSV infection include acute onset of fever, and focal neurological symptoms and signs, especially of temporal lobe.
Diagnosis :
§CSF protein and CSF lymphocytosis §Brain biopsy is gold standard
§HSV DNA detection in CSF by PCR has largely replaced biopsy
Treatment : IV acyclovir