This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Brain , Subject name: Anatomy
Hippocampus is connected to hypothalamus by which structure? 
Select and explain. 
A. Fornix, B. Mammilary bodies, C. Median forebrain bundles, D. Septal nuclei
A: Fornix
Answer: A: Fornix 
Explanation: Fornix is a large bundle of mainly projection fibres which connect the hippocampus with the mammillary body. It constitutes the sole efferent system of the hippocampus. *The medial forebrain bundle (MFB), is a pa of reward system, containing fibers from the basal olfactory regions, periamygdaloid region septal nuclei, as well as fibers from ventral tegmental area. (Reference: Vishram Singh textbook of clinical neuroanatomy Second Edition page 231)