This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Vitamins and Minerals, Subject name: Biochemistry
Which of the following deficiency can cause generalized oedema: 
Select and explain. 
A. Vitamin B2, B. Vitamin B6, C. Vitamin B12, D. Vitamin B1
D: Vitamin B1
Answer: D: Vitamin B1 
Explanation: Vitamin B1 deficiency is Beri-Beri, which can cause oedema in "Wet Beri-Beri" which affects CVS, leading to cardiac failure, pulmonary & peripheral oedema. Other clinical manifestations of Beri-Beri: