This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
In glycolysis, the first committed step is catalysed by 
Select and explain. 
A. 2, 3 DPG, B. Glucokinase, C. Hexokinase, D. Phosphofructokinase
D: Phosphofructokinase
Answer: D: Phosphofructokinase 
Explanation: Phosphofructokinase catalyzes the committed step of glycolysis, meaning that once fructose 1, 6 - bisphosphate is formed it must go for the glycolytic pathway only.