This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Thalidomide can be used in all of the following conditions, EXCEPT: 
Select and explain. 
A. Behcet's syndrome, B. HIV associated peripheral neuropathy, C. HIV associated mouth ulcers, D. Erythema nodosum leprosum
B: HIV associated peripheral neuropathy
Answer: B: HIV associated peripheral neuropathy 
Explanation: Thalidomide has been used for many years in the treatment of some manifestations of leprosy and has been used for erythema nodosum leprosum; it is also useful in management of the skin manifestations of lupus erythematosus. The most impoant toxicity is teratogenesis. Because of this effect, thalidomide prescription and use are closely regulated by the manufacturer. Other adverse effects of thalidomide include peripheral neuropathy, constipation, rash, fatigue, hypothyroidism, and increased risk of deep vein thrombosis. In more serious cases of Behcet syndrome, thalidomide (100 mg/d) is effective. Ref: Lake D.F., Briggs A.D., Akporiaye E.T. (2012). Chapter 55. Immunopharmacology. In B.G. Katzung, S.B. Masters, A.J. Trevor (Eds), Basic & Clinical Pharmacology, 12e.