This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Which of the following is a Dihydropteroate synthase (DHPS) inhibitor? 
Select and explain. 
A. Pyrimethamine, B. Trimethoprim, C. Methotrexate, D. Dapsone
D: Dapsone
Answer: D: Dapsone 
Explanation: Dapsone, PAS, Sulphonamide > inhibit DHPS enzyme Pyrimethamine, Methotrexate, Trimethoprim - acts by inhibiting DHFR (Dihydrofolate reductase) enzyme.