This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Rheumatic Fever, Subject name: Pathology
Antischkow cells seen in all except 
Select and explain. 
A. Systemic sclerosis, B. Rheumatic Fever, C. Iron def Anemia, D. Recurrent aphthous stomatitis
A: Systemic sclerosis
Answer: A: Systemic sclerosis 
Explanation: Anitschkoff cell are also k/a caterpillar cell because their nuclear material is clumped in a wavy form. Conditions it can be seen in are: Rheumatic Fever Recurrent aphthous stomatitis Iron deficiency anemia Megaloblastic anemia Sickle cell anemia ANITSCKOFF CELLS. Systemic sclerosis is characterized by: (1) chronic inflammation thought to be the result of autoimmunity (2) widespread damage to small blood vessels (3) progressive interstitial and perivascular fibrosis in the skin and multiple organs.