This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Probenecid does NOT decrease the renal excretion of the following drug: 
Select and explain. 
A. Ketoprofen, B. Methotrexate, C. Rifampin, D. Penicillin
C: Rifampin
Answer: C: Rifampin 
Explanation: Probenecid decreases the biliary secretion of rifampin, leading to higher plasma concentrations. Probenecid inhibits the tubular secretion of drugs, such as: Methotrexate Active metabolite of clofibrate Inactive glucuronide metabolites of NSAIDs such as naproxen, ketoprofen, and indomethacin Penicillin Cephalosporins Ref: Grosser T., Smyth E. (2011). Chapter 34. Anti-inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In L.L. Brunton, B.A. Chabner, B.C. Knollmann (Eds), Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e.