This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous (Gynae), Subject name: Gynaecology & Obstetrics
Predisposing factors of carcinoma endometrium are all EXCEPT 
Select and explain. 
A. Obesity, B. Late menopause, C. Multiparity, D. Unopposed administration of estrogen
C: Multiparity
Answer: C: Multiparity 
Explanation: (Multiparity) (573-74-Shaw's 14th)Multiparity is common in carcinoma cervix, while carcinoma of endometrium women are either nulliparous or of low parityPredisposing Factors in Carcinoma Endometrium* Peak incidence is 55-70 years* An Early menarche and late menopause is characteristic* Unopposed and unsupervised administration of HRT* Chronic non ovulatory cycles as seen in DUB* Familial predisposition - Familial Lynch II syndrome* Tamoxifen given to women with breast cancer increases the risk of endometrial hyperplasia* Combined oral hormonal pills* Obesity hypertension and diabetes* Infertile women and women with polycystic ovarian disease* Feminizing ovarian tumour at the time of diagnosis* The risk of endometrial carcinoma is the highest with the following complex hyperplasia with atypia** histological pattern of endometrial hyperplasia (about 28%)***