This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: ENT
All statement about Plummer–Vinson syndrome are true except - 
Select and explain. 
A. Commonly leads to carcinoma in lower third of esophagus, B. Common with iron deficiency, C. Common in females, D. Premalignant
A: Commonly leads to carcinoma in lower third of esophagus
Answer: A: Commonly leads to carcinoma in lower third of esophagus 
Explanation: Plummer-Vinson syndrome

Plummer-Vinson syndrome, also known as Brown-Kelly-Paterson syndrome or sideropenic dysphagia, seen in middle-aged edentulous women.
The plummer Vision Paterson Brown-Kelly Syndrome is characterized by : -


Dysphagia
Chronic iron deficiency anaemia
Atrophic oral mucosa and glossitis
Brittle, spoon-shaped fingernails (Koilonychia)


The cause of dysphagia is usually a cervical esophageal web, but abnormal pharyngeal and esophageal motility may play a role.
The syndrome characteristically occurs in middle-aged edentulous (without teeth) women.
It is a premalignant lesion. Approximately 10% of patient develop squamous cell Ca of esophagus, oral cavity or the hypopharynx.
As iron-deficiency anemia is a common finding, it is also known as sideropenic dysphagia.
Carcinoma develops in the postcricoid region (not in the lower third oesophagus).