This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General anatomy, Subject name: Anatomy
When nitrates are combined with Calcium channel blockers 
Select and explain. 
A. Aerial pressure will decrease, B. Hea rate will increase, C. Ejection time will decrease, D. End diastolic volume will increase
A: Aerial pressure will decrease
Answer: A: Aerial pressure will decrease 
Explanation: Really Kk sharma 1e p276 Recommendations for combination therapy decisively depend on the choice of the first-line drug. Only nitrates reduce myocardial preload by venodilation and substitute for EDRF-deficiency. ... Therefore, the combination of nitrates with hea-rate-increasing calcium channel blockers, such as nifedipine, should be avoided.