This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Autonomic nervous system, Subject name: Pharmacology
Tiotropium is contraindicated in: 
Select and explain. 
A. Bronchial asthma, B. Hypeension, C. Urinary retention, D. Peptic ulcer disease -
C: Urinary retention
Answer: C: Urinary retention 
Explanation: Ref:KD Tripathi pharmacology 7th edition (page.no: 114,115,117) Actions of Tiotropium bromide are - bronchodilatation, Decreased gastric secretion so, it's not contraindicated in peptic ulcer Tiotropium acts on M3 receptors- block them and cause urinary retention. so it is contraindicated in urinary retention.