This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Physiology
Estrogen action on carbohydrate metabolism 
Select and explain. 
A. Increases uptake of glucose through increase in insulin sensitivity, B. Glycolysis increases, C. Increasing central adipose deposition, D. Worsening of NIDDM
A: Increases uptake of glucose through increase in insulin sensitivity
Answer: A: Increases uptake of glucose through increase in insulin sensitivity 
Explanation: Reduced estrogen may also lower metabolic rate, the rate at which the body conves stored energy into working energy. It's possible the same thing happens with women when estrogen levels drop after menopause. Some evidence suggests that estrogen hormone therapy increases a woman's resting metabolic rate. Ref: guyton and hall textbook of medical physiology 12 edition page number:637,638,639