This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Massive splenomegaly with pancytopenia - 
Select and explain. 
A. CLL, B. Pure red cell aplasia, C. CML, D. Myelofibrosis
D: Myelofibrosis
Answer: D: Myelofibrosis 
Explanation: Ans. is 'd' i.e., Myelofibrosiso Massive splenomegaly is referred to as extension of spleen greater than 8 cm below the left costal margin or weight of spleen more than 1 Kg.o Causes of massive Splenomegaly are - CML Polycythemia vera Autoimmune hemolytic anemia Lymphomas Gaucher's disease Diffuse splenic hemangiomatosis Hairy cell leukemia CLL Myelofibrosis Sarcoidosiso Amongst these conditions pancytopenia is seen in i.e., massive splenomegaly with pancytopenia : - o Hairy cell leukemia Myelofibrosis Gaucher's disease