This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Alzheimer's disease associated chromosome is 
Select and explain. 
A. 2, B. 6, C. 12, D. 19
D: 19
Answer: D: 19 
Explanation: In familial Alzheimer disease and down syndrome. The gene encoding APP on chromosome 21 is involved.
The genitic locus on chromosome 19 that encodes apolipoprotein E (ADOE) has a strong inthences on the risk of developing AD.