This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Ophthalmology
Contraindication of topical beta blockers – 
Select and explain. 
A. Hypertension, B. Asthma, C. Tachycardia, D. Hypotension
B: Asthma
Answer: B: Asthma 
Explanation: β-blockers (non-selective) :- Asthma, COPD, CHF, sinus bradycardia, AV block
Cholinomimetic (Pilocarpine) :- Uveitis
Sympathomimetic agents


Dipiveferine :- Angle closure glaucoma, cardiovascular disease.
Brimonidine, Apraclonidine: - Use of MAO inhibitors, hypertensive crisis, Parkinsonism.


Carbonic anhydrase inhibitors: - Hypersensitivity to sulfonamide, eye injury.
Prostaglandin analogues: - Ocular inflammation or infection.