This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Skin
Acantholytic cell in pemphigus is derived from : 
Select and explain. 
A. Stratum granulosum, B. Stratum basale, C. Stratum spinosum, D. Langerhan's cell
C: Stratum spinosum
Answer: C: Stratum spinosum 
Explanation: C i.e. Stratum spinostunPemphigus (vulgarisQ, vegetans, foliaceus, erythematous, endemic, paraneoplasticQ) causes intra epidermalQ and PemphigoidQ (bullous, cicatricial, gestations, linear IgA disease) causes sub epidermal bullae formation(2. Blisters (vesicles, bullae or split) are intra epidermal in pemphigus and subepidermal in pemphigoid and dermatitis herpetiformisQ