This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Tadpole cells/comma shaped cells on histopathology are seen in - 
Select and explain. 
A. Trichoepithelioma, B. Spideroma, C. Rhabdomyosarcoma, D. Histiocytoma
C: Rhabdomyosarcoma
Answer: C: Rhabdomyosarcoma 
Explanation: Histology of rhabdomyosarcoma 

The diagnostic cell of rhabdomyosarcoma is rhabdomyoblast.
Rhabdomyoblast contains eccentric eosinophilic granular cytoplasm rich in thick and thin filaments.
The rhabdomyoblasts may be -


Round
Elongated → Tadpole or Strap cells.


It has three variants


Embryonal
Alveolar
Pleomorphic


Rhabdomyoblasts are positive for desmin, MYOD1 and Myogenin.