This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Dental
Most common unfavourable sequelae of serial extraction: 
Select and explain. 
A. Disto-axial inclination of canine, B. Residual space at the extraction site, C. Mesio-axial inclination of second premolar, D. Increase in overbite
D: Increase in overbite
Answer: D: Increase in overbite 
Explanation: Early extraction of the buccal teeth and uprighting of incisors can result in deepening of the bite. This can be corrected with bite plane.
Ref: textbook of orthodontics gowrishankar 2nd edition page 533