This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Respiratory chain, Subject name: Biochemistry
NADH CoQ reductase is inhibited by 
Select and explain. 
A. Rotenone, B. CO, C. Antimycin, D. Atractyloside
A: Rotenone
Answer: A: Rotenone 
Explanation: Inhibitors of electron transpo chainComplex I Complex II Complex III Complex IV AmobarbitalRotenonePericidin AGuanethidine Chlorpromazine Malonate Carboxin Antimycin A, BAL Naphthoquinone PhenforminCarbon monoxide CyanideHydrogen sulphide Azide Inhibitors of oxidative phosphorylationuBlocking reentry of protons through ATP synthase - Oligomycin , VenturicidinuInhibitors of ATP - ADP exchange - Atractyloside , BongregateuIonophores - Valinomycin , GramicidinUncouplers of oxidative phosphorylationuPhysiological uncouplers - Thermogenin, Thyroxine, Long chain fatty acids, Unconjugated bilirubinuSynthetic uncouplers - 2,4 Dinitrophenol, 2,4 Dinitrocresol, Calcium, Aspirin, DicoumarolHarper's illustrated Biochemistry , 30th ed , page 133