This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Infection, Subject name: Medicine
Which one of the following is the drug of choice for treating systemic fungal infection ? 
Select and explain. 
A. Griseofolvin, B. Amphotericins, C. Ketoconazole, D. trimoxazole
B: Amphotericins
Answer: B: Amphotericins 
Explanation: Amphotericin B is an antifungal medication used for serious fungal infections and leishmaniasis. The fungal infections it is used to treat include aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, and cryptococcosis. For ceain infections it is given with flucytosine Ref Harrison20th edition pg 1078