This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Rofecoxib was withdrawn due to : 
Select and explain. 
A. Ischemic heart disease, B. Renal complication, C. Liver adenoma, D. Gastric ulcer
A: Ischemic heart disease
Answer: A: Ischemic heart disease 
Explanation: None