This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Glycogen, Subject name: Biochemistry
A10-year-old boy rapidly develops hypoglycemia after moderate activity. Blood examination reveals raised ketone bodies, lactic acid, and triglycerides. On examination, the liver & kidneys were enlarged. Histopathology of the liver shows deposits of glycogen in excess amount. What is the diagnosis? 
Select and explain. 
A. Von Gierke disease, B. Pompe's disease, C. Mc Ardle's disease, D. Forbe's disease
A: Von Gierke disease
Answer: A: Von Gierke disease 
Explanation: Most common glycogen storage disease presenting with hypoglycemia and normal glycogen structure is Von Gierke disease, Von Gierke disease is due to deficiency of glucose-6-phosphatase. affects only liver Clinical features: severe hypoglycemia ketosis massive hepatomegaly enlarged kidneys hyperiglyceridemia lactic acidosis hyperuricemia Spleen not enlarged