This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.N.S, Subject name: Pharmacology
In depression, there is deficiency of: 
Select and explain. 
A. 5-HT, B. Acetylcholine, C. Dopamine, D. GABA
A: 5-HT
Answer: A: 5-HT 
Explanation: Ans. (A) 5-HT(Ref: Katzung 10/e p475; KDT 8/e p483)Monoamines like serotonin and nor-adrenaline are deficient in depressive patients, therefore reuptake inhibitors of these monoamines are used for treatment of depression.