This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Which one of the listed statements is the best histologic definition of an abscess? 
Select and explain. 
A. A circumscribed collection of neutrophils with necrotic cellular debris, B. A localized defect that results from the sloughing of necrotic inflammatory tissue from the surface of an organ, C. A localized proliferation of fibroblasts and small blood vessels, D. An aggregate of two or more activated macrophages
A: A circumscribed collection of neutrophils with necrotic cellular debris
Answer: A: A circumscribed collection of neutrophils with necrotic cellular debris 
Explanation: An abscess is a localized collection of neutrophils and necrotic debris. It is basically a localized form of suppurative (purulent) inflammation, which is associated with pyogenic bacteria and is characterized by edema fluid admixed with neutrophils and necrotic cells (liquefactive necrosis or pus).