This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Medicine
Cause of dysphonia and hoarseness of voice includes 
Select and explain. 
A. Thiamine, B. Pyridoxine, C. Vitamin B12, D. Folic Acid
A: Thiamine
Answer: A: Thiamine 
Explanation: (A) Thiamine # WERNICKE-KORSAKOFF SYNDROME, which combines Wernicke encephalopathy and Korsakoff psychosis, occurs in some alcoholics who do not consume foods fortified with thiamin.> Wernicke encephalopathy consists of psychomotor slowing or apathy, nystagmus, ataxia, ophthalmoplegia, impaired consciousness, and, if untreated, coma and death. It probably results from severe acute deficiency superimposed on chronic deficiency.> Korsakoff psychosis consists of mental confusion, dysphonia, and confabulation with impaired memory of recent events. It probably results from chronic deficiency and may develop after repeated episodes of Wernicke encephalopathy.