This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
All of the following statements are true about theophylline except - 
Select and explain. 
A. Increase in dose is required in cardiopulmonary disease, B. Increases cAMP, C. Increase in dose is required in smokers, D. Inhibits phosphodiesterase
A: Increase in dose is required in cardiopulmonary disease
Answer: A: Increase in dose is required in cardiopulmonary disease 
Explanation: Ans. is 'a' i.e., Increase in dose is required in Cardiopulmonary disease o Pneumonia and CHF (Cardiopulmonary disease) require dose reduction (not increased dose). o Other options are correct.