This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Impoant Viral Diseases in Children, Subject name: Pediatrics
Appropriate therapy with antiretroviral agents results in a syndrome characterized by an increased inflammatory response from the recovered immune system to subclinical oppounistic infection. What is this syndrome called as? 
Select and explain. 
A. HIV related hyper- reactivity syndrome, B. AIDS related inflammatory syndrome, C. Immune reconstitution inflammatory syndrome, D. CD4 responsive inflammatory syndrome
C: Immune reconstitution inflammatory syndrome
Answer: C: Immune reconstitution inflammatory syndrome 
Explanation: Immune reconstitution inflammatory syndrome (IRIS)- characterized by increased inflammatory response, subclinical oppounistic infections. common in patients with severe CD4 + T-lymphocyte depletion There is fever & worsening of clinical manifestations of oppounistic infection or new manifestations (e.g., enlargement of lymph nodes, pulmonary infiltrates), typically within the 1st few weeks after initiation of antiretroviral therapy.