This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Which of the following liver enzymes is predominantly mitochondrial 
Select and explain. 
A. SGOT (AST), B. SGPT (ALT), C. GGT, D. 5' Nucleotidase
A: SGOT (AST)
Answer: A: SGOT (AST) 
Explanation: Liver enzymes location 

Ectoenzymes (Plasma membrane-bound) :- 5' nucleotidase (also called nucleotide phosphatase, NTP), Gamma-glutamyl transferase (gamma-glutamyl transpeptidase : GGT), alkaline phosphatase (ALP).
Mitochondrial:- Glutamate dehydrogenase (GDH), Aspartate aminotransferase (AST) or SGOT mitochondrial isoenzyme.
Cytosolic:- Lactate dehydrogenase (LDH), Alanine transaminase (ALT) or SGPT, SGOT (AST) cytosolic isoenzyme.

Note:- In liver, the predominant isoenzyme of SGOT (AST) is mitochondrial.