This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General anatomy, Subject name: Anatomy
Poal Acinus means 
Select and explain. 
A. The space between two central veins of adjacent lobules, B. The space between two hepatic ducts, C. The space between central vein and bile duct, D. The space between Poal vein and central vein
A: The space between two central veins of adjacent lobules
Answer: A: The space between two central veins of adjacent lobules 
Explanation: The hepatic or poal acinus is the functional unit of the liver.The acinus consists of an irregular shaped, roughly ellipsoidal mass of hepatocytes aligned around the hepatic aerioles and poal venules just as they anastomose into sinusoids.The acinus is roughly divided into zones that correspond to distance from the aerial blood supply - those hepatocytes closest to the aerioles (zone 1 below) are the best oxygenated, while those fahest from the aerioles have the poorest supply of oxygen. This arrangement also means that cells in the center of the acinus (again, zone 1) are the first to "see" and potentially absorb blood-borne toxins absorbed into the poal blood from the small intestine.Reference: Krishna Garg Histology; 5th edition; Page no: 171