This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Central Nervous system, Subject name: Pharmacology
Relatively safe drug for epileptic patients in pregnancy? 
Select and explain. 
A. Carbamazepine, B. Phenobarbitone, C. Valproate, D. Phenytoin
B: Phenobarbitone
Answer: B: Phenobarbitone 
Explanation: Barbiturates are relatively safe in pregnancy for epilepsy. Lamotrigine, Levetiracetam, topiramate are also relatively safe teratogencity ladder levetiacetam,lamotrigine>phenobarbitone ,phenytoin>carbamazepine,topiramate>valproate Ref: KD Tripathi 8th ed.