This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Which of the following drugs should not be given in a patient with acute angle-closure glaucoma: 
Select and explain. 
A. Pilocarpine, B. Clozapine, C. Fluphenazine, D. Paroxetine
B: Clozapine
Answer: B: Clozapine 
Explanation: In angle-closure glaucoma, anticholinergic and sympathomimetic drugs should be avoided.
Among the given options, except for Pilocarpine, all are anticholinergic.
Most anti cholinergic among Clozapine, fluphenazine and paroxetine is Clozapine.