This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Bacterial Infection of Skin, Subject name: Skin
True about Lucio's phenomenon is- 
Select and explain. 
A. Associated with tuberculoid leprosy, B. Occurs as side effect of treatment of leprosy, C. Ischemic necrosis, D. Also known as type 2 Lepra reaction
C: Ischemic necrosis
Answer: C: Ischemic necrosis 
Explanation: Ans. is 'c' i.e. Ischemic necrosis * Lucio's phenomenon is seen in untreated cases of lepromatous leprosy.Lucio's phenomenon* Lucio's phenomenon is seen in lepromatous leprosy (LL). It occurs in patients who are untreated. Patients develop recurrent crops of large sharply marginated, ulcerative lesions, particularly on lower extrimities. It is due to heavy parasitism of endothelial cell, endothelial proliferation and thrombus formation which lead to ischemic necrosis.