This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pharmacology
Flushing is common in patient taking which of the follwing oral hypoglycemic drug with alcohol: 
Select and explain. 
A. Chlorprompamide, B. Phenformin, C. Glibenclamide, D. Tolazamide
A: Chlorprompamide
Answer: A: Chlorprompamide 
Explanation: Chlorpropamide is a first generation sulphonylurea. It causes cholestatic jaundice, intolerance to alcohol in predisposed subjects(flushing and a disulfiram like reaction). Disulfiram like reaction seen with: chlorpropomide, tolbutamide, metronidazole, gresiofulvin, cefoperazone, cefomandole etc (REF.Essential of medical pharmacology K D TRIPATHI 6 Edition, Page No - 267)