This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Dental
Which of the following is the second most common congenital defect in entire spectrum of congenital deformities? 
Select and explain. 
A. Clubfoot, B. Cleft lip and palate, C. Osteogenesis imperfecta, D. Ectodermal dysplasia
B: Cleft lip and palate
Answer: B: Cleft lip and palate 
Explanation: Cleft lip and palate is the most common congenital defect of facial structures and the second most congenital defect in the entire spectrum of congenital deformities (first common is clubfoot).