This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Apoptosis, Subject name: Pathology
Apoptosis causes all except: 
Select and explain. 
A. Activation of caspase, B. Local inflammatory response, C. Condensation of chromatin, D. Cleavage of chromatin by endonucleases
B: Local inflammatory response
Answer: B: Local inflammatory response 
Explanation: Features of Necrosis and Apoptosis Necrosis Apoptosis * Always pathological * May be physiological or pathological * Associated with disruption of cellular homeostasis (e.g. ischemia, hypoxia & poisoning) * Impoant for development, homeostasis & elimination of pathogens & tumor cells * Affects contiguous (adjacent) group of cells * Affect single cells * Cell size is increased * Cell size is shrunken * Passive * Active * Causes inflammatory reaction * No inflammatory reaction * Plasma membrane is disrupted * Plasma membrane is not disrupted * 'Smear pattern' on electrophoresis * Step ladder pattern on electrophoresis