This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Prolactin secretion is inhibited by - 
Select and explain. 
A. Dopamine antagonist, B. GABA, C. Neurophysin, D. Bromocripitine
D: Bromocripitine
Answer: D: Bromocripitine 
Explanation: Ans. is 'd' i.e., Bromocriptine o Prolactin is under predominant inhibitory control of hypothalamus through prolactin releasing inhibitory hormone (PRIH). o PRIH is a dopamine that acts on pituitary lactotrope D, receptor. So, Dopaminergic agonists decrease plasma prolactin levels. These agonists are : Dopamine Cobergoline Bromocriptine Apomorphine Dopaminergic antagonists and DA depleters will increase prolactin level Dopaminergic antagonists are : Dopamine depleters are : o Chlorpromazine o Reserpine o Haloperidol o Methyl dopa o Metoclopramide