This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
Cause of clostridium difficile associated diarrhea - 
Select and explain. 
A. Trauma, B. Dairy products, C. Fried rice, D. Antibiotic use
D: Antibiotic use
Answer: D: Antibiotic use 
Explanation: Prolonged broad spectrum antibiotic therapy is the most important risk factor for Clostridium difficile associated diarrhea
Ref: Apurba Sastry’s Essentials of Medical Microbiology 1/e p265, Ananthanarayan 9/e p265