This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pathology
Which of the following mechanisms is not responsible for complications in DM 
Select and explain. 
A. Non enzymatic glycosylation, B. Protein Kinase C activation, C. Disturbance in polyol pathway, D. Chronic inflammation
D: Chronic inflammation
Answer: D: Chronic inflammation 
Explanation: The things responsible for chronic complications of DM are 1)Formation of Advanced glucation end products 2) Activation of Protein Kinase C 3)Oxidative stress and disturbance in Polyol pathways . Possible complications include: Cardiovascular disease. ... Nerve damage (neuropathy). ... Kidney damage (nephropathy). ... Eye damage (retinopathy). ... Foot damage. ... Skin conditions. ... Hearing impairment. ... Alzheimer's disease Ref: Robbins and cotrans 9e Pg 1116