This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
Type-I hypersensitivity is mediated by which of the following immunoglobulins: 
Select and explain. 
A. IgA, B. IgG, C. IgM, D. IgE
D: IgE
Answer: D: IgE 
Explanation: IgE