This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
"Chicken-wire" appearance of enlarged bone marrow spaces is seen in: 
Select and explain. 
A. Fetal alcohol syndrome, B. Sickle cell anaemia, C. Haemophilia A, D. Beta thalassemia major
D: Beta thalassemia major
Answer: D: Beta thalassemia major 
Explanation: In the jaws in beta thalassemia, there is generalized rarefraction of alveolar bone, thinning of cortical bone, and a “chicken-wire” appearance of enlarged marrow spaces and coarse trabeculation. 
In some cases, the lamina dura may be thin, the roots of the teeth short, and the premaxilla prominent.

Poynton HG: Oral radiology, Baltimore, 1982, Williams & Wilkins, Page: 230-232.