This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Autacoids, Subject name: Pharmacology
Which of the following drugs have covalent interaction with its target 
Select and explain. 
A. Aspirin, B. Penicillin, C. Nitric oxide, D. Basanta
A: Aspirin
Answer: A: Aspirin 
Explanation: covalent interaction means Irreversible inhibition of enzyme. Aspirin irreversibly acitylates the cox enzyme Refer kDT 6/e p185