This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
A patient with recurrent bacterial infections is diagnosed to have a genetic deficiency in myeloperoxidase. The cause of increased susceptibility to infections is - 
Select and explain. 
A. Defective neutrophil degranulation, B. Defective production of prostaglandins, C. An inability to produce hydroxyhalide radicals, D. Decreased oxygen consumption after phagocytosis
C: An inability to produce hydroxyhalide radicals
Answer: C: An inability to produce hydroxyhalide radicals 
Explanation: Ans. is 'c' i.e., An inability to produce hydroxyhalide redicalso Myeloperoxidase in the presence of halide (C1 ) conves H202 to hypochlorite (HOCI). HOCI is a potent microbicidal agent that destroys microbes by halogenation or by oxidation of lipids and proteins. The H202 myeloperoxidase halide system is the most efficient bactericidal system in neutrophils.