This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: FMGE 2018, Subject name: Anaesthesia
False statement about post-dural puncture headache (PDPH): 
Select and explain. 
A. Breach of dura, B. Onset of headache is usually 12-72 hours following procedure, C. Commonly occipito - frontal in location, D. Headache is relieved in sitting standing position
D: Headache is relieved in sitting standing position
Answer: D: Headache is relieved in sitting standing position 
Explanation: Post Dural puncture Headache Pathophysiology - CSF leak - ICP |es - Traction on nerve fibres originating from piamater Site - Occipital > Frontal > Retrorbital Duration - 7-10 days Pathognomic sign - Change in posture aggravates headache Predisposing conditions - Dura cutting needle (spinal needle)* Most commonly seen with 22G Quincke needle Wide bore needle * Multiple attempts * Pregnancy (In pregnancy dura mater is very fragile- venous engorgement fragility increases chances of PDPH is more) Note- Early ambulation never predispose to PDPH