This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Which is the most common mutation in Hereditary spherocytosis 
Select and explain. 
A. Glycophorin, B. Band 3, C. Ankyrin, D. Spectrin
C: Ankyrin
Answer: C: Ankyrin 
Explanation: Ankyrin mutation is most common in HS. Spectrin mutation correlates with severity of anemia in HS.