This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: NSAIDs, Gout and Rheumatoid Ahritis, Subject name: Pharmacology
Which of the following is a recommended step in management of salicylate poisoning? 
Select and explain. 
A. Chelating agents, B. Atropine, C. Alkaline diuresis, D. Observation
C: Alkaline diuresis
Answer: C: Alkaline diuresis 
Explanation: In acidic drug poisoning (salicylate, barbiturates, chlorpropamide, methotrexate etc.) urine should be alkalinized with sodium bicarbonate because weak acids are in ionized form in alkaline urine and thus are easily excreted. Chelating agents are used for heavy metal poisoning. Atropine is drug of choice for organophosphate poisoning