This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
In a patient if administration of vasopressin does not increase the osmolality of urine, it indicates? 
Select and explain. 
A. ADH deficieny, B. Renal hyposensitivity towards ADH, C. SIADH, D. Psychogenic polydipsia
B: Renal hyposensitivity towards ADH
Answer: B: Renal hyposensitivity towards ADH 
Explanation: Renal hyposensitivity towards ADH REF: Harrison's 17th ed p. 274 If the osmolality of urine increases after administration of ADH - Nephrogenic DI (Renal hyposensitivity) If the osmolality of urine decreases after administration of ADH- Central DI