This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Which of the following is responsible for adhesion of platelets to the vessel wall? 
Select and explain. 
A. Von Willebrand factor, B. Factor IX, C. Fibrinogen, D. Fibronectin
A: Von Willebrand factor
Answer: A: Von Willebrand factor 
Explanation: the Von-Willebrand factor is responsible for adhesion of platelets to the vessel wall.
“Endothelial injury allows platelets to contact the underlying extracellular matrix;
subsequent adhesion occurs through interactions with von Willebrand factor (VWF),
which is a product of normal endothelial cells and an essential cofactor for platelet binding to matrix elements."—