This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Social & Preventive Medicine
Which of the following drugs has the highest bactericidal activity against Mycobacterium leprae? 
Select and explain. 
A. Rifampicin, B. Clofazimine, C. Dapsone, D. Minocycline
A: Rifampicin
Answer: A: Rifampicin 
Explanation: Rifampicin has a high bactericidal activity against M. leprae. A single dose of 1500 mg appears to kill 99% of the organisms. Ref: Park 21st edition, page 296.