This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Blood, Subject name: Pathology
Which will the patient with following peripheral smear and X-ray spine present with? 
Select and explain. 
A. Hand Foot syndrome, B. Black urine, C. Elevated haptoglobin, D. Splenomegaly with gall stones
A: Hand Foot syndrome
Answer: A: Hand Foot syndrome 
Explanation: Ref: Harsh Mohan, Textbook of Pathology, 7th ed. pg. 294-96The X-ray spine shows fish shaped vertebra with peripheral smear showing sickle shaped RBCs. The presence of sickling crisis lead to Hand-Foot syndrome is characterized by painful infarcts of the digits and dactylitis.