This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Medicine
A patient presents with intermittent headache. On examination there is hypeension and a thyroid nodule. Which of the following steps is to be taken next - 
Select and explain. 
A. Urine HIAA levels, B. Urine VMA and aspiration of the thyroickiodule, C. Ultrasound abdomen, D. Echocardiography
B: Urine VMA and aspiration of the thyroickiodule
Answer: B: Urine VMA and aspiration of the thyroickiodule 
Explanation: Ans is option 2.. Urine VMA and aspiration of thyroid nodule. Intermittent headache (common symptom of pheochromocytoma) and thyroid nodule points towards Pheochromocytoma with medullary carcinoma thyroid Which inturn is a feature of MEN || syndrome Pheochromocytoma is diagnosed by demonstrating excretion of Catecholamines or its metabolites in urine Medullary Ca of thyroid is diagnosed by aspiration of thyroid nodule Ref Harrison 17/e p 2361