This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General Concepts, Subject name: Pathology
All of the following are characteristics of malignant tumours, except: 
Select and explain. 
A. Loss of polarity, B. Metaplasia, C. Nuclear pleomorphism, D. Metastasis
B: Metaplasia
Answer: B: Metaplasia 
Explanation: Features of malignant neoplasms: Lack of differentiation (anaplasia) Frequent mitosis Cellular and nuclear pleomorphism Loss of polarity Ischemic necrosis Local invasion Metastasis Metaplasia is defined as the replacement of one type of cell with another type. Metaplasia is nearly always found in association with tissue damage, repair, and regeneration. Metaplastic epithelium is prone to malignant transformation, but metaplasia per se is not a feature of malignancy.