This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Pathology
Aplastic anemia can progress to all except 
Select and explain. 
A. AML, B. Myelodysplastic anemia, C. Pure red cell aplasia, D. Paroxysmal nocturnal hemoglobinuria
C: Pure red cell aplasia
Answer: C: Pure red cell aplasia 
Explanation: Pure red cell aplasia (PRCA) is a form of BMF characterized by severe anaemia with reticulocytopenia and reduced erythroid progenitors in the bone marrow. PRCA most commonly is an acquired disorder and immune mediated, and often occurs in association with a wide range of conditions.hence it is totally unrelated to aplastic anemia. emedicine.medscape.com