This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Condition which can present both as nephritic syndrome and nephrotic syndrome, is: March 2012 
Select and explain. 
A. Minimal change disease, B. Acute proliferative glomerulonephritis, C. Rapidly progressive glomerulonephritis, D. Membranoproliferative glomerulonephritis
D: Membranoproliferative glomerulonephritis
Answer: D: Membranoproliferative glomerulonephritis 
Explanation: Ans: D i.e. Membranoproliferative glomerulonephritis Glomerular pathology and presentation Most frequent clinical presentation of minimal change disease is that of nephrotic syndrome Most frequent clinical presentation of acute proliferative glomerulonephritis/post-infectious glomerulonephritis is that of nephritic syndrome Most frequent clinical presentation of rapidly progressive/crescentic glomerulonephritis is that of nephritic syndrome Membranoproliferative glomerulonephritis/MPGN accounts for 10-20% of cases of nephritic syndrome in children and young adults. Some patients present only with hematuria or proteinuria in the non-nephrotic range, but many others have a combined nephritic-nephrotic picture.