This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Psychiatry
Amyloid pressure protein is cleaved by ______ and ________ in Alzheimer's disease 
Select and explain. 
A. α secretase , γ  secretase, B. α secretase ,  β secretase, C. β secretase ,  γ secretase, D. β secretase , α  secretase
C: β secretase ,  γ secretase
Answer: C: β secretase ,  γ secretase 
Explanation: Amyloid precersor protein(APP) is normaly cleaved by α and  β secretases.
In Alzeihmer's disease it is cleaved by  β and γ secretases and forms AB peptide that deposit to form senile plaques.