This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.V.S, Subject name: Medicine
Risk factors for coronary aery disease 
Select and explain. 
A. High HDL, B. Low HDL, C. Increased homocysteine levels, D. Decreased fibrinogen levels
C: Increased homocysteine levels
Answer: C: Increased homocysteine levels 
Explanation: Ref Harrison 19 th ed pg 1579 The major risk factors for atherosclerosis (high levels of plasma low-density lipoprotein , low plasma high-density lipoprotein , cigarette smoking, hypeension, and diabetes mellitus disturb the normal functions of the vascular endothelium.