This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Disorders of pituitary gland, Subject name: Medicine
Which is not a feature of Kallman syndrome? 
Select and explain. 
A. Micropenis, B. Primary amenorrhea, C. Mirror movements of hands, D. Mental retardation
D: Mental retardation
Answer: D: Mental retardation 
Explanation: Kallman Syndrome occurs due to defective synthesis of GnRH (Gonadotropin releasing hormone). KAL gene is X linked. During fetal life, the GnRH neurons originate in Olfactory Placode and then migrate along fetal olfactory neuron. They eventually wend their way to the hypothalamus. Presenting features Associated with Males: delayed pubey and micro-penis. Females: Primary amenorrhea and failure of development of secondary sexual characteristics Anosmia Colour blindness, optic atrophy SN deafness Mirror movements of hands (synkinesia) Cleft palate Renal abnormalities Mirror movements