This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Which of the following antitubercular drugs are associated with hypothyroidism? 
Select and explain. 
A. Ethionamide, B. Streptomycin, C. PZA, D. Rifampicin
A: Ethionamide
Answer: A: Ethionamide 
Explanation: Ethionamide is thought to prevent organification of iodine in thyroid hormone synthesis, as it is structurally related to other thionamides (propylthiouracil and methimazole). So, it can lead to hypothyroidism.