This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Anemia, splenomegaly, structural defects are seen in: 
Select and explain. 
A. Thalassemia major, B. Thalassemia minor, C. Mediteranean anemia, D. Polycythemia
A: Thalassemia major
Answer: A: Thalassemia major 
Explanation: None