This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
In which of the following vegetation are friable and easily detachable from the cardiac valves - 
Select and explain. 
A. Rheumatic fever, B. Rheumatoid hea, C. SLE, D. Infective endocarditis
D: Infective endocarditis
Answer: D: Infective endocarditis 
Explanation: Ans. is 'd' i.e., Infective endocarditis o The hallmark of infective endocarditis is the presence of large, friable, bulky, potentially destructive vegetation containing fibrin, inflammatory cell, and bacteria. o Emboli may be shed from vegetation at any time because of detachment. Also know o Vegetations of NBTE may also be friable and detachable to produce emboli. But they are small and non-destructive.