This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
All of the following diuretics acts from luminal side of renal tubules except: 
Select and explain. 
A. Loop diuretics, B. ENAC  blockers, C. Aldosterone antagonists, D. Mannitol
C: Aldosterone antagonists
Answer: C: Aldosterone antagonists 
Explanation: Aldosterone receptor antagonists acts from interstitial side.