This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
Retinoblastoma is associated with- 
Select and explain. 
A. Osteosarcoma, B. Hepatocellular, C. SCC, D. Osteoclastoma
A: Osteosarcoma
Answer: A: Osteosarcoma 
Explanation: Robbins basic pathology 9th edition page no 777 Pathogenesis Several mutations are associated with the devolopmeny of osteosarcoma. The patients with hereditory retinoblastomas have a thousand fold greater risk for devolopment of osteosarcoma.