This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous (Bio-Chemistry), Subject name: Biochemistry
NADP is not needed in: 
Select and explain. 
A. Steroid synthesis, B. Urea synthesis, C. Fatty acid synthesis, D. Reduced glutathione synthesis
B: Urea synthesis
Answer: B: Urea synthesis 
Explanation: Ans: b (Urea synthesis) Ref: Lippincott, 23th ed, p. 145; Vasudevan, 4th ed, p. 284; 5th ed, p. 181NADPH uses:Fatty acid synthesisSources of NADPH:Cholesterol synthesisGeneration of superoxide in phagocytosisNucleotide synthesisGlutathione reductionSynthesis of spingolipids. steroidsPhenyl alanine to tyrosineMet Hb to HbUronic acid pathwayDrug metabolismHMP shunt.Malic enzyme (malate to pyruvate).Cytoplasmic isocitrate dehydrogenase.6- Phosphogluconate dehydrogenase in the shunt pathway.(Glucose-6 Po4 - 6- Phosphogluconolactone)