This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Anatomy
Increase in alkaline phosphatase is seen in: 
Select and explain. 
A. Chronic myeloid leukemia, B. Leukemoid reaction, C. Eosinophilia, D. Malaria
B: Leukemoid reaction
Answer: B: Leukemoid reaction 
Explanation: LAP is found in the membranes of secondary granules of neutrophils. Its activity is measured in mature neutrophils and band cells only. Esinophils donot show alkaline phosphatase activity and must not be mistaken with mature neutrophils with a score of zero.Malaria is characterized by monocytosis.( ref Robbins 8/e p595, 9/e p584)