This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
T cell independent Antigen acts through  which one of the following? 
Select and explain. 
A. T-cell, B. B-cell, C. Macrophages, D. CD8+ T cells
B: B-cell
Answer: B: B-cell 
Explanation: None