This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Mendalian Inheritance, Subject name: Biochemistry
Which of the following is not an epigenetic change? 
Select and explain. 
A. Acetylation of histone, B. Methylation of DNA, C. Methylation of histone, D. Point mutation
D: Point mutation
Answer: D: Point mutation 
Explanation: Epigenetics Study of heritable gene expression without change in the nucleotide sequences. Major epigenetic mechanisms: DNA methylation Histone modifications Alteration in Chromatin Structure microRNAs Point mutation Changes the nucleotide sequence. Does not come under the definition of epigenetic change.