This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Blood Vessels, Subject name: Pathology
In atherosclerosis, increased LDL in monocyte macrophage due to: 
Select and explain. 
A. LDL receptors on macrophage, B. LDL receptors on endothelium, C. Lipids in LDL get oxidized, D. All of the above
C: Lipids in LDL get oxidized
Answer: C: Lipids in LDL get oxidized 
Explanation: Ans. (c) Lipids in LDL get oxidized(Ref: Robbins 9th/pg 496; 8th/pg 500)With chronic hyperlipidemia, lipoproteins accumulate within the intima, there they aggregate and become oxidized by free radicals produced by inflammatory cells.