This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
A 50 year old male, working as a hotel cook, has four dependent family members. He has been diagnosed with an early stage squamous cell cancer of anal canal. He has more than 60% chances of cure. Which of the following is the best treatment option? 
Select and explain. 
A. Chemotherapy alone, B. Abdominoperineal resection, C. Combined surgery and radiotherapy, D. Combined chemotherapy and radiotherapy
D: Combined chemotherapy and radiotherapy
Answer: D: Combined chemotherapy and radiotherapy 
Explanation: A combination of chemotherapy and radiotherapy, so-called chemo radiation (Nigro) is the preferred initial therapy for all anal canal tumours. In such patients a combination of 5 flourouracil and mitomycin is given for approximately 1 week and chemotherapy is followed by radiotherapy, given over 3-7 weeks. Ref: Bailey and Love's Sho Practice of Surgery, 24th Edition, Pages 1269-1271.