This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Fatal familial insomnia is associated with : 
Select and explain. 
A. Prion disease, B. Degenerative disease, C. Neoplastic disease, D. Vascular disease
A: Prion disease
Answer: A: Prion disease 
Explanation: Answer is A (Prion Disease): Fatal familial insomnia is one of the commonly caused prion disease. PRIONS refer to a class of proteinacious infectious paicles without any detectable nucleic acid i.e. 'virus like paicles without the nucleic acid components'. - Ananthnarayan 6th /416 As can be expected they are sensitive to proteasesQ (contain protein) but resistant to nucleasese (do not contain nucleic acid) as well as to heat & UV rays. The most commonly caused prion diseases include`: Kura Creutzfeildt - Jakob diseaseQ Gestermann - Straussler - Scheinker syndrome Q Fatal familial insomnia Q