This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Adrenal, Subject name: Medicine
A 40 years old lady comes with Pheochromocytoma. Most characteristic symptom is? 
Select and explain. 
A. Sweating attacks, B. Weight loss, C. Orthostatic hypotension, D. Paroxysmal hypertension
D: Paroxysmal hypertension
Answer: D: Paroxysmal hypertension 
Explanation: ANSWER: (D) Paroxysmal hypertensionREF: Harrisons Internal Medicine chapter 337 Pheochromocytoma Table 337-1Repeat December 2009, June 2010Pheochromocytomas and paragangliomas are catecholamine-producing tumors derived from the sympathetic or parasympathetic nervous system. These tumors may arise sporadically or be inherited as features of multiple endocrine neoplasia type 2.The "rule of tens" for pheochromocytomas states that about 10% are bilateral, 10% are extraadrenal, and 10% are malignant. However, these percentages are higher in the inherited syndromes.The clinical presentation is so variable that Pheochromocytoma has been termed "the great masquerader". The dominant sign is hypertension. Classically, patients have episodic hypertension, but sustained hypertension is also frequent.CLINICAL FEATURES ASSOCIATED WITH PHEOCHROMOCYTOMAHeadachesWeight lossSweating attacksParadoxical response to antihypertensive drugsPalpitation and tachycardiaPolyuria and polydipsiaHypertension, sustained or paroxysmalConstipationAnxiety and panic attacksOrthostatic hypotensionPallorDilated cardiomyopathyNauseaErythrocytosisAbdominal painElevated blood sugarWeaknessHypercalcemia