This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology and breast, Subject name: Surgery
Which of the following does not alter the &;T&; stage in breast cancer? 
Select and explain. 
A. Peaud's orange, B. Skin ulceration, C. Pectoral muscle involvement, D. Serratus anterior muscle muscle involvement
C: Pectoral muscle involvement
Answer: C: Pectoral muscle involvement 
Explanation: .Manchester Staging 1. Tumour in the breast, not involving pectoral or deeper plane. Skin involvement if present, it is lesser than the size of tumour. Lymph nodes are not palpable. 2. Same as stage I but with mobile, discrete lymph nodes palpable in the ipsilateral axilla. 3. Tumour fixed to pectoral muscle, or skin involvement more than the tumour size or ipsilateral axillary lymph nodes adherent to each other or fixed. 4. Tumour fixed to the chest wall, 'cancer-en-cuirasse', skin involvement wider than that of the breast, involvement of ipsilateral or contralateral supraclavicular lymph nodes or opposite breast or opposite axillary lymph nodes, spread to bone, lung, liver or inflammatory carcinoma of breast. ref:SRB&;s manual of surgery,ed 3,pg no 476