This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General anatomy, Subject name: Anatomy
True about subcutaneous nodules in rheumatic fever 
Select and explain. 
A. Non tender, B. Most common manifestation, C. Present in flexor surfaces, D. Associated with ahritis
A: Non tender
Answer: A: Non tender 
Explanation: Ref Harrison 19 th ed pg 2152 Subcutaneous nodules occur as painless, small (0.5-2 cm), mobile lumps beneath the skin overlying bony prominences, paicularly of the hands, feet, elbows, occiput, and occasionally the veebrae. They are a delayed manifestation, appearing 2-3 weeks after the onset of disease, last for just a few days up to 3 weeks, and are commonly asso- ciated with carditis.