This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
Which malignancy would occur in long standing multinodular goiter ? 
Select and explain. 
A. Papillary Carcinoma, B. Follicular Carcinoma, C. Anaplastic Carcinoma, D. Medullary Carcinoma
B: Follicular Carcinoma
Answer: B: Follicular Carcinoma 
Explanation: Incidence of follicular carcinoma is high in endemic goitrous areas, with long standing multinodular goiter, possibly owing to persistent TSH stimulation.
Dominant or rapidly growing nodules especially in longstanding goiters should always be subjected to aspiration cytology.