This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
Omalizumab True statement is? 
Select and explain. 
A. Anti-IgE, B. Used as add on therapy in moderate to severe asthma prophylaxis, C. Givn subcutaneously, D. All o above
D: All o above
Answer: D: All o above 
Explanation: Ans. is 'd' i.e., All of above Anti-IgE (Omalizumab). Omalizumab is a humanized monoclonal antibody that binds IgE, thereby preventing its binding to the high-affinity IgE receptor and blocking IgE-mediated allergic responses and inflammation. approved for patients >12 yr old with moderate to severe asthma, It is given every 2-4 wk subcutaneously based on body weight and serum IgE levels. Its clinical efficacy as an "add-on" therapy for patients with moderate to severe allergic asthma It is generally well tolerated, although local injection site reactions can occur