This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
All of the following about loop diuretics are true about except: 
Select and explain. 
A. Ethacrynic acid is the most ototoxic loop diuretic, B. They release prostaglandins and lead  to vasodilation, C. Loop diuretics lead to hypokalemia and metabolic alkalosis, D. Furosemide is the most potent loop diuretic
D: Furosemide is the most potent loop diuretic
Answer: D: Furosemide is the most potent loop diuretic 
Explanation: Bumetanide is the most potent loop diuretic.