This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Antenatal Care & Assessment of Fetal Well Being, Subject name: Gynaecology & Obstetrics
When heparin is given in pregnancy, which of the following is to be added? 
Select and explain. 
A. Iron folic acid, B. Copper, C. Calcium, D. Zinc
C: Calcium
Answer: C: Calcium 
Explanation: Ans. is c, i.e. CalciumRef. KDT 6/e, p 598, 599; Harrison 17/e, p 2400Heparin can lead to osteoporosis, or hypocalcemia so, calcium supplementation is advisable with the use of heparin.Also Know:Durgs which may lead to hypocalcemia and hence calcium supplementation is necessary:CorticosteroidsCyclosporineAnticonvulsantsCytotoxic drugsExcessive alcoholAromatase inhibitorIncrease dose of thyroxineAluminiumGnRHHeparinLithium