This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.V.S., Subject name: Pediatrics
Thalassemia gives protection against: 
Select and explain. 
A. Filaria, B. Kala-azar, C. Malaria, D. Leptospirosis
C: Malaria
Answer: C: Malaria 
Explanation: c. Malaria(Ref: Nelson's 20/e p 2349', Ghai 8/e p 341)Thalassemia gives a reduced parasite invasion/growth and an increased susceptibility to phagocytosis of the infected RBC as a malaria-protective effect.