This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
A 50 years old male presents with massive splenomegaly. His differential diagnosis will include all, except 
Select and explain. 
A. Chronic mycloid leukemia, B. Polycythemia rubra vera, C. Hairy cell leukemia, D. Aplastic anemia
D: Aplastic anemia
Answer: D: Aplastic anemia 
Explanation: Diseases Associated with massive splenmegaly.



Chronic myclogenous leukemia
Gaucher's disease


Lymphomas
Chronic lymphocytic leukemia


Hairy cell leukemia
Sarcoidosis


Myelofibrosis with myeloid metaplasia
Autoimmune hemolytic anemia


Polycythemia vera
Diffuse splenic human giomatosis