This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrine, Subject name: Pathology
Gs-alpha mutation my lead to? 
Select and explain. 
A. Mccune Albright syndrome, B. Pseudohypoparathyroidism, C. Pituitary adenomas, D. All of the above
D: All of the above
Answer: D: All of the above 
Explanation: Ans. (d) All of the above(Ref: Robbins 9th/pg 1077, 1101; 8th/pg 1101, 1127)GSaLoss of functionGain of functionGain or loss of function* Pseudohypopar- athyroidim type la* Pseudohypopar- athyroidim type lb* Pituitary or thyroid adenomas* Leydig cell tumors* McCune-Albright syndrome* Testotoxicosis with pseudohypoparathyroidism type laGi2a: Gain of function* Pituitary adenomas* Adrenal cortex and ovary tumors