This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Disorders of pituitary gland, Subject name: Medicine
The following are recognized features of pan-hypopituitarism except? 
Select and explain. 
A. Increased insulin sensitivity, B. Pigmentation of the mucous membranes, C. Low serum thyroxine and TSH levels, D. Loss of secondary sex characters
B: Pigmentation of the mucous membranes
Answer: B: Pigmentation of the mucous membranes 
Explanation: Since ACTH has a paial MSH(Melanocyte Stimulating Hormone) like activity and levels of ACTH in Pan-hypopituitarism will fall, the hyperpigmentation cannot occur. However diseases with Increased ACTH like Addison disease will show hyperpigmentation. Insulin sensitivity implies hypoglycemia. LH/FSH fall will cause loss of secondary sexual features.