This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Pathology
Which of the following is not the cause of macrocytic anaemia ?- 
Select and explain. 
A. Orotic aciduria, B. Abetalipoproteinemia, C. Lesh nyhan disease, D. Transcobalamine deficiency
C: Lesh nyhan disease
Answer: C: Lesh nyhan disease 
Explanation: Lesch nyhan syndrome is due to deficiency are complete or paial absence of HGP enzyme. It does not involve any type of anaemia Reference : textbbook: pathologic basis of disease Author : Robbins and cotron , volume2 , page number 1215