This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Autonomic nervous system, Subject name: Pharmacology
Clonidine is used for: 
Select and explain. 
A. Migraine, B. Opioid withdrawal syndrome, C. Diabetic diarrhea, D. All of the above
D: All of the above
Answer: D: All of the above 
Explanation: ref;KD Tripathi 7the edition pharmacology (page no;565,567) Clonidine is an imidazoline derivative and agonist for a2 receptors, especially a2A subtype the in brainstem. uses : Opioid withdrawal, Alcohol withdrawal, Postoperative analgesia, Control loose motion due to Diabetec neuropathy, Migraine, hypeension (nowadays not used due to withdrawal hypeension), post menopausal hot flushes