This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Intravenous Anesthetic Agents, Subject name: Anaesthesia
Which is a specific antagonist of benzodiazepine :- 
Select and explain. 
A. Zaleplon, B. Flumazenil, C. Naloxone, D. Zopiclone
B: Flumazenil
Answer: B: Flumazenil 
Explanation: Flumazenil is a specific and exclusive benzodiazepine antagonist. It presents and reverses in a dose dependent names all the agonist effects of benzodiazepine. Flumazenil is the first benzodiazepine antagonist approved for clinical use to reverse the effects of benzodiazepines. It is a competitive antagonist at the benzodiazepine receptor and produces antagonism that is reversible. It is a benzodiazepine receptor ligand which has a high affinity and specificity. Flumazenil is used for both diagnostic and therapeutic reversal of benzodiazepine receptor agonists.