This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Most important prognostic factor for carcinoma breast is 
Select and explain. 
A. Skin involvement, B. Tumor size, C. Chest wall involvement, D. Lymph node involvement
D: Lymph node involvement
Answer: D: Lymph node involvement 
Explanation: Spread to axillary nodes is the most important prognostic indicator. 
Other prognostic factors are
Age: Younger the age worse the prognosis. 
Sex: Carcinoma male breast has got worse prognosis compared to the female breast. Because of early spread in carcinoma male breast.
Stage I and II have got a better prognosis. 
Atrophic scirrhous has got the best prognosis.
Medullary carcinoma has got better prognosis than scirrhous carcinoma because of lymphocytic infiltration.
Invasive carcinoma has got a worse prognosis. 
Inflammatory carcinoma breast has the worst prognosis.