This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Virology, Subject name: Microbiology
Presence of Hbe Ag in patients with hepatitis indicates - 
Select and explain. 
A. Simple carriers, B. Late convalescence, C. High infectivity, D. Carrier status
C: High infectivity
Answer: C: High infectivity 
Explanation: HBeAg appears in blood concurrently with HBsAg or soon afterward. Circulating HBeAg is an indicator of active intrahepatic viral multiplication, and the presence in blood of DNA polymerase, HBV DNA and virions, reflecting high infectivity. REF:ANANTHANARAYAN AND PANIKER'S TEXTBOOK OF MICROBIOLOGY 9TH EDITION PAGE NO-547