This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Toll like receptors, recognize bacterial products and stimulates immune response by, 
Select and explain. 
A. Perforin and granzyme mediated apoptosis, B. Transcriptions of nuclear factor mediated by NFKP which recruits cytokines, C. FADD ligand apoptosis, D. Cyclin
B: Transcriptions of nuclear factor mediated by NFKP which recruits cytokines
Answer: B: Transcriptions of nuclear factor mediated by NFKP which recruits cytokines 
Explanation: The Toll-like receptors are membrane proteins that recognize a variety of microbe-derived molecules and stimulate innate immune responses against the microbes.
The Toll-like receptors are expressed on many different cell types that participate in innate immune responses including macrophages, dendritic cells, neutrophils, NK cells, mucosal epithelial cells and endothelial cells.
Signalling by Toll like receptors results in the activation of transcription factors. notably NF-K0 and AP-L
The genes that are expressed in response to TLR signalling encode proteins important in many different components of innate immune response.
These include
Inflammatory cytokines (TNF, IL-1, IL-2)
Endothelial adhesion molecules (E-selection) and
Proteins involved in microbial killing mechanisms.