This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nephritic & Nephrotic Syndrome, Subject name: Pediatrics
Steroid resistance nephrotic syndrome is defined as failure to achieve remission after:- 
Select and explain. 
A. 4 weeks of daily Coicosteroid therapy, B. 6 weeks of daily Coicosteroid therapy, C. 8 weeks of daily Coicosteroid therapy, D. 12 weeks of daily Coicosteroid therapy
C: 8 weeks of daily Coicosteroid therapy
Answer: C: 8 weeks of daily Coicosteroid therapy 
Explanation: NELSON : Steroid Resistance. Steroid resistance is defined as the failure to achieve remission after 8 wk of coicosteroid therapy. GHAI 9E : Steroid resistance is diagnosed, if there is lack of remission despite treatment with prednisolone, at a dose of 2 mg/kg/day(60mg/m2/day)for 4weeks followed by 1.5mg/kg (40 mg/m2) on alternate days for another4 weeks Nephrotic syndrome (NPHS2-related), also known as steroid-resistant nephrotic syndrome