This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Adrenal Gland, Subject name: Pathology
Treatment with anti-hypeensive drug spironolactone leads to formation of spironolactone bodies in: 
Select and explain. 
A. Adrenal coex, B. Adrenal medulla, C. Renal coex, D. Renal medulla
A: Adrenal coex
Answer: A: Adrenal coex 
Explanation: Aldosterone-producing adenomas Solitary, small (<2 cm in diameter), well-circumscribed lesions Bright yellow on cut section and, surprisingly, are composed of lipid-laden coical cells that more closely resemble fasciculata cells than glomerulosa cells (the normal source of aldosterone). Hallmark feature is presence of eosinophilic, laminated cytoplasmic inclusions, known as spironolactone bodies, found after treatment with the antihypeensive drug spironolactone. Do not suppress ACTH secretion. Adjacent adrenal coex and that of the contralateral gland are not atrophic.