This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Proton pump inhibitors for peptic ulcer disease should be taken: 
Select and explain. 
A. After Breakfast, B. Before Dinner, C. Before Breakfast, D. After Dinner
C: Before Breakfast
Answer: C: Before Breakfast 
Explanation: For ideal action of proton pump inhibitor, an acidic pH in the parietal cell canaliculi is prerequisite because the drug is activated in this acidic pH.
Hence it should be taken at least 30 minutes before meals.
It is preferably administered before breakfast so that peak serum concentration coincides with maximum activity of proton pump secretion.