This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Disorder of Metabolism & Connective Tissue, Subject name: Medicine
History of dislike for sweet food items is typically present in: 
Select and explain. 
A. Diabetes mellitus, B. Glycogen storage disease, C. Hereditary fructose intolerance, D. Galactosemia
C: Hereditary fructose intolerance
Answer: C: Hereditary fructose intolerance 
Explanation: Ans. is 'c' i.e. Hereditary fructose intoleranceRef.: Harrison 17th/e p 2458 & 16th/e p 2321 (15th/e p2289) In hereditary fructose intolerance patients are healthy and asymptomatic until fructose or sucrose (table sugar) is ingested. With the ingestion of sugar severe clinical symptoms appear. Which are -JaundiceHepatomegalyVomitingLethargyIrritabilityConvulsionsProteinuriaHereditary fructose intolerance is caused by the deficiency of Aldolase B.Aldolase B catalyzes the following reactionFructose - 1 - phosphate Aldolase B Glyceraldehyde* Dihydroxyacetone phosphate Deficiency of this enzyme causes rapid accumulation of fructose -1- phosphate and initiates severe toxic symptoms when exposed to fructose.Diagnosis -It is diagnosed by the presence of reducing substance (fructose) in the urine.The appearance of hypoglycemia and hypophosphatemia after fructose (200 mg/kg) loading is diagnosticTreatment:Treatment consists of eliminating fructose from the dietAs affected individuals grow up they may recognize the association of nausea and vomiting with fructose containing foods and selectively avoids them