This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
The therapeutic advantage that pencillin V has over
pencillin G is: 
Select and explain. 
A. More reliable oral absorption, B. Greater resistance to pencillinase, C. Slower renal excretion, D. Broader antibacterial spectrum
A: More reliable oral absorption
Answer: A: More reliable oral absorption 
Explanation: ACID-RESISTANT  ALTERNATIVE  TO PENICILLIN-G 
Phenoxymethyl penicillin (Penicillin V) 
It differs from PnG only in that it is acid stable. Oral absorption is better; peak blood level is reached in 1 hour and plasma  t½  is 30-60 minutes.
The antibacterial spectrum of penicillin V is identical to PnG, but it is about 1/5 as active against Neisseria, other gram negative bacteria and anaerobes.