This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Immunoglobulins are formed by? 
Select and explain. 
A. Plasma cells, B. T-cells, C. B-cells, D. Macrophages
A: Plasma cells
Answer: A: Plasma cells 
Explanation: Plasma cells are the antibody-secreting cells. On contact with its appropriate antigen, the mature B cell undergoes clonal proliferation. The majority of activated B cells are transformed into plasma cells and secrete antibodies
While plasma cell is the best antibody-producing cell, lymphocytes, lymphoblasts and transitional cells may also synthesise Ig to some extent.