This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Malabsorbtion Syndrome, Subject name: Medicine
Which is the most impoant complication of celiac sprue? 
Select and explain. 
A. Intestinal neoplasm, B. Diabetes mellitus, C. Dermatitis herptiformis, D. Bile acid diarrhea
A: Intestinal neoplasm
Answer: A: Intestinal neoplasm 
Explanation: The most impoant complication of celiac sprue is development of cancer both intestinal and non-intestinal neoplasms and lymphomas. Celiac sprue Complications Associated with Intestinal neoplasms/ lymphoma Refractory sprue Collagenous sprue Dermatitis herpetiformis Type 1 DM IgA deficiency Down ,Turner syndrome