This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Small & Large Intestine, Subject name: Surgery
All are true about pouchitis except: 
Select and explain. 
A. Probiotics have shown promising response, B. Cause may be related to mucosal ischemia, C. Most commonly seen in ulcerative colitis surgeries, D. Episodes of pouchitis will not respond to antibiotics
D: Episodes of pouchitis will not respond to antibiotics
Answer: D: Episodes of pouchitis will not respond to antibiotics 
Explanation: Ans. (d) Episodes of pouchitis will not respond to antibioticsTreatment protocol for pouchitis:* 1st line: Ciplox + Metronidazole* 2nd line: Probiotics added* 3rd line: Add ASA compounds* 4th line: Pouchectomy and permanent ileostomy