This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Ophthalmology
Most B/L multifocal retinoblastoma require 
Select and explain. 
A. Chemotherapy, B. Radiotherapy, C. Enucleation, D. Multi Modality therapy
D: Multi Modality therapy
Answer: D: Multi Modality therapy 
Explanation: D i.e. Multi Modality therapy Multi Modality Therapy Most children with bilateral retinoblastoma, multifocal RB, or bothQ, and occasion children with unilateral RB, are managed by multimodality therapy.