This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Regional anaesthesia, Subject name: Anaesthesia
The topical use of following local anesthetic is not recommended? 
Select and explain. 
A. Ligocaine, B. Bupivacaine, C. Cocaine, D. Dibucaine
B: Bupivacaine
Answer: B: Bupivacaine 
Explanation: Bupivacine cannot be used as surface anesthetic agent Bupivacine is also contraindicated in regional IV anesthesia or Bier&;s block due to fear of cardiac arrhythmia It can be used in peripheral nerve block, epidural and intrathecal routes