This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
Hypergonadotropic hypogonadism ? 
Select and explain. 
A. Decrease FSH and LH, B. Decrease FSH and increase LH, C. Increase FSH increase LH, D. Increase FSH decrease LH
C: Increase FSH increase LH
Answer: C: Increase FSH increase LH 
Explanation: Ans. is '-c' i.e., Increase FSH increase LH Hypergonadotropic hypogonadism Also K/a primary or peripheral hypogonadism. Characterised by hypogonadism due to an impaired response of the gonads to the gonadotropin, FSH and LH. In turn a lack of sex steroid production and elevated gonadotropin level(FSH and LH). Causes : Chromosomal abnormalitis Turner's syndrome Klinefelter syndrome Swyer's syndrome Enzyme defect 17 , hydroxylase 17, 20 lyase deficiency