This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Anaesthesia
Local Anesthetic first used clinically aEUR' 
Select and explain. 
A. Procaine, B. Lignocaine, C. Bupivacaine, D. Cocaine
D: Cocaine
Answer: D: Cocaine 
Explanation: Cocaine [Ref- Miller Anaesthesia, Lee Synopsis of Anaesthesia I2th/e p. 591-5921 The origin of modern local anaesthesia is credited to Carl poller, an ophthalanzologist who demonstrated the use of topical cocaine for surgical anaesthesia of the eye. - Cocaine had been isolated from the coca plant in 1855 by Gaedicke and later purified in 1860 by Albe neimann. - In 1884 the Surgeon William Halsted demonstrated the use of cocaine for intradermal infiltration and nerve blocks (including the .facial nerve, the brachial plexus, the pudendal nerve and posterior tibial nerve).