This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Psychiatry
Wernicke&;s encephalopathy in alcohol consumption can be treated with 
Select and explain. 
A. Pyridoxine, B. Thiamine, C. Riboflavin, D. Niacin
B: Thiamine
Answer: B: Thiamine 
Explanation: Alcohol-Induced Amnestic Disorder: (1) Wernicke's encephalopathy, Confabulation, Ataxia, Ophthalmoplegia (gaze palsy, lateral orbital palsy)horizontal nystagmus tends to reverse rapidly with thiamine supplementation. it can be remebered with a mnemonic GOA G====Global confusion O====ophthalmoplegia A====Ataxia (2) Korsakoff's syndrome (permanent in 50 to 70%): anterograde, retrograde amnesia and potential impairment in visuospatial, abstract, and other types of learning. .They respond to 50 to 100 mg of oral thiamine a day, usually administered for many months. Both are due to thiamine deficiency, causing neuropathological lesions symmetrically in mammillary bodies, thalamus, hypothalamus, midbrain, pons, medulla, fornix, and cerebellum. Reference: P.1279 11.2 Alcohol-Related DisordersKaplan & Sadock's Comprehensive Textbook of Psychiatry, 9th Ed