This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
Chromosome associated with familial polyposis colon ? - 
Select and explain. 
A. Chromosome 5, B. Chromosome 6, C. Chromosome 11, D. Chromosome 13
A: Chromosome 5
Answer: A: Chromosome 5 
Explanation: Robbins and Cotran pathologic basis of disease South Asia edition APC is a member of the class of tumor suppressor that function by downregulating growth promoting signalling pathway . Germline loss of function mutation involving the APC which is present in chromosome 5 are associated with familial adenomatous poliposis..