This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Which of the following syndrome is most commonly associated with clefts of lip and palate 
Select and explain. 
A. Apert syndrome, B. Crouzon syndrome, C. Pierre-Robin syndrome, D. Down’s syndrome
C: Pierre-Robin syndrome
Answer: C: Pierre-Robin syndrome 
Explanation: Although most clefts of the lip and palate occur as an isolated deformity, Pierre Robin sequence remains the most common syndrome.
This syndrome comprises of isolated cleft palate, retrognathia and a posteriorly displaced tongue (glossoptosis), which is associated with early respiratory and feeding difficulties.