This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Sandhoff's disease is due to absence of which enzyme? 
Select and explain. 
A. Beta–hexosaminidase, B. Beta–glucuronidase, C. Aryl sulphatase, D. Alpha galactosidase
A: Beta–hexosaminidase
Answer: A: Beta–hexosaminidase 
Explanation: Beta-hexosaminidase 

Sandhoff's disease is due to deficiency of Beta Hexosaminidase.