This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney Stones & Renal Tubular Acidosis, Subject name: Medicine
Dent's disease is characterized by all except? 
Select and explain. 
A. Chloride channel defect, B. Males are affected, C. Nephrolithiasis, D. Defect in limb of Loop of Henle
D: Defect in limb of Loop of Henle
Answer: D: Defect in limb of Loop of Henle 
Explanation: Dent disease X-linked recessive disorder of proximal renal tubular dysfunction characterized by low molecular weight proteinuria, nephrolithiasis, and chronic kidney disease Males are affected mutation in CLCN5