This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Which is not a minor criteria of Multiple Myeloma? 
Select and explain. 
A. Multiple lytic lesions, B. Plasmacytosis > 20%, C. Plasmacytoma in tissue, D. S. IgG > 3gm, IgA > 1.5
C: Plasmacytoma in tissue
Answer: C: Plasmacytoma in tissue 
Explanation: Answer is C (Plasmacytoma on Tissue Biopsy) Plasmacytoma on tissue biopsy iv a major criterion for diagnosis of Multiple Myeloma and not a minor criterion.