This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General anatomy, Subject name: Anatomy
True statement about the drug of Administration is 
Select and explain. 
A. 80% bioavailability by I.V. injection, B. I.M. administration needs sterile technique, C. I.D. injection produce local tissue necrosis and irritation, D. Inhalation route produces delayed systemic bioavailability
B: I.M. administration needs sterile technique
Answer: B: I.M. administration needs sterile technique 
Explanation: 1)100%. bioavailability is seen in case of IV route. 2)sterile technique is needed in case of I.V. and I.M. administration. 3)Irritation and loal tissue necrosis is seen in case of imetable routes like intramuscular or s.c. route. 4)In inhalational route, absorption of drugs takes place.from vast suaces of alveoli-so bioavailability is high and action is very rapid. Ref-KDT 6/e p91