This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
All of the following host tissue responses can be seen in acute inflammation, EXCEPT: 
Select and explain. 
A. Exudation, B. Margination, C. Vasodilation, D. Granuloma formation
D: Granuloma formation
Answer: D: Granuloma formation 
Explanation: Vasodilation, margination and exudation are host tissue responses seen during acute inflammation. Granulomas are seen in chronic inflammation. The three major components of acute inflammation are: ? Alteration in vascular caliber that lead to an increase in blood flow. ? Emigration of the leukocytes from the microcirculation and their accumulation in the focus of injury. ? Structural changes in the microvasculature that permits the plasma proteins and leukocytes to leave the circulation. Ref: Robbins Pathologic Basis of Disease, 6th Edition, Page 83 and 8th Edition, Page 73