This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Physiological changes during Pregnancy, Subject name: Gynaecology & Obstetrics
The clotting factor which is not increased in pregnancy: 
Select and explain. 
A. Factor 2, B. Factor 7, C. Factor 10, D. Factor 11
D: Factor 11
Answer: D: Factor 11 
Explanation: Ans. is d, i.e. Factor 11Ref: Dutta Obs 9/e, p 48Pregnancy is a hypercoaguable state, all clotting factors increase in pregnancy except factor 11 and 13. Another frequently asked question is what happens to fibrinogen levels during pregnancy-since fibrinogen is clotting factor number 1 therefore it also increase in pregnancy.