This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: FMGE 2017, Subject name: Pharmacology
Which of the following anti-diabetic drugs are associated with weight gain? 
Select and explain. 
A. Acarbose, B. Metformin, C. Sitagliptin, D. Pioglitazone
D: Pioglitazone
Answer: D: Pioglitazone 
Explanation: Pioglitezone Only one thiazolidinedione, pioglitazone is currently available in india C/I in liver and hea failure Selective agonist for PPAR ? ( peroxisome proliferator activated receptor ?) Lower serum triglyceride level ,raises HDL level Reverse insulin resistance