This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Pathology
A 53-year-old man presents to his physician's office for an insurance physical. During the history, you learn that his father had diabetes and died of congestive hea failure. The patient was told it was due to "bronze diabetes." The patient complains only of vague fatigue and ahralgias. You are concerned that the patient may be at risk for hereditary hemochromatosis. Which test would you order to confirm your suspicion? 
Select and explain. 
A. Antimitochondrial antibodies, B. Ceruloplasmin, C. Heterophil antibodies, D. Transferrin saturation
D: Transferrin saturation
Answer: D: Transferrin saturation 
Explanation: The recommended screening test for hemochromatosis is serum transferrin saturation Molecular testing can be performed to look for mutations in the HFE gene on chromosome 6. Early detection and occasional phlebotomy can prevent multi-organ failure attributed to iron accumulation in tissues. -Antimitochondrial antibodies are used in the diagnosis of primary biliary cirrhosis. -Ceruloplasmin levels are decreased in Wilson disease.