This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Dental
A complete denture patient presents with angular cheilitis. A review of recent medical examination revealed that vitamin deficiency is not a factor. A possible predisposing factor is _____. 
Select and explain. 
A. Excessive vertical dimension of occlusion, B. A closed or insufficient vertical dimension of occlusion, C. Improper balance of the occlusion, D. Poor contour of the denture base
B: A closed or insufficient vertical dimension of occlusion
Answer: B: A closed or insufficient vertical dimension of occlusion 
Explanation: A closed or insufficient vertical dimension of occlusion is thought to be one predisposing condition for angular cheilitis, which usually is associated with Candida albicans. Improperly balanced occlusion or poor contour of the denture base are not predisposing conditions for angular cheilitis.