This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Central Nervous system, Subject name: Pharmacology
The antiepilectic drug which does not produce enzyme induction is 
Select and explain. 
A. Phenobarbitone, B. Sodium valproate, C. Phenytoin sodium, D. Carbamazepine
B: Sodium valproate
Answer: B: Sodium valproate 
Explanation: The four major enzyme-inducing AEDs (carbamazepine, phenytoin, phenobarbital and primidone) stimulate the metabolism and reduce the serum concentration of most other concurrently administered AEDs, most notably valproic acid , tiagabine , ethosuximide , lamotrigine , topiramate , REF : KD TRIPATHI 8TH ED.