This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
Side effect of clomephine citrate includes all except : 
Select and explain. 
A. Multiple pregnancy, B. Increase risk of ovarian ca, C. Multiple polycystic ovary, D. Teratogenic effect on off springs
D: Teratogenic effect on off springs
Answer: D: Teratogenic effect on off springs 
Explanation: Ans. is d i.e. Teratogenic effect on offsprings Side effects of clomiphene : Increase risk of multiple pregnancy * Increase cances of enlargement, pain, cystic changes, Hot flushes haemorrhage and multiple ovulation in the ovaries. Nausea, vomitting * Increase risk of ovarian cancer Headache * Increase rate of aboion Visual disturbances * Alopecia (rare) and galactorrhoea (rare). Ovarian hyperstimulation syndrome "Two-to-three fold increased risk of neural tube defect has been repoed by many. though not proved." But it is not suppoed by other books. There is no substantial evidence that clomiphene treatment increases the overall risk of bih defects or any one anomaly in paicular"