This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Blood Physiology, Subject name: Physiology
Which transfusion will result in a transfusion reaction? Assume that the patient has never had a transfusion 
Select and explain. 
A. Type O Rh-negative packed cells to an AB Rh-positive patient, B. Type A Rh-positive packed cells to an A Rh-negative patient, C. Type AB Rh-positive packed cells to an AB Rh-positive patient, D. Type A Rh-positive packed cells to an O Rh-positive Patient
D: Type A Rh-positive packed cells to an O Rh-positive Patient
Answer: D: Type A Rh-positive packed cells to an O Rh-positive Patient 
Explanation: Type O RBCs are considered to be universal donor blood. Reactions occur between the recipient's antibody and donor antigen as shown in the following table. Donor Donor antigen Recipient Recipient Antibody Reaction O - negative None AB - positive None None A - positive A, Rh A - negative B None AB-positive A,B, Rh AB-positive None None A - positive A, Rh O - positive A, B A (antigen and A (antibody)