This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Myocardial Infarction, Subject name: Pathology
Earliest light microscopic change in myocardial infarction is: 
Select and explain. 
A. Waviness of the fibers, B. Neutrophilic infiltration, C. Phagocytic infiltration, D. Coagulative necrosis
A: Waviness of the fibers
Answer: A: Waviness of the fibers 
Explanation: When there is depletion of ATP, there is development of swelling in Myofibers leading to the haphazard arrangement of fibres causing waviness of the fibers. The typical changes of coagulative necrosis become detectable in the first 6 to 12 hours. "Wavy Fibers" may be present at the periphery of the infarct. These changes probably result from the forceful systolic tugs of the ble fibers on immediately adjacent, noncontractile dead fibers, causing stretching and folding.