This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunology, Subject name: Microbiology
Marker of chronic inflammation is? 
Select and explain. 
A. IL-1, IL-6, B. IL-1, TNF, C. IL-6, TNF, D. IL-12, IFN-g
D: IL-12, IFN-g
Answer: D: IL-12, IFN-g 
Explanation: Interleukin 12 and Interferon-gamma are the major markers of chronic inflammation. REF:Textbook of microbiology, Ananthanarayan, and Paniker.