This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Anatomy
Hippocampus is connected to the hypothalamus by which structure? 
Select and explain. 
A. Fornix, B. Mammilary bodies, C. Median forebrain bundles, D. Septal nuclei
A: Fornix
Answer: A: Fornix 
Explanation: The fornix is a large bundle of mainly projection fibres which connect the hippocampus with the mammillary body. It constitutes the sole efferent system of the hippocampus.
The medial forebrain bundle (MFB), is a part of the reward system, containing fibers from the basal olfactory regions, periamygdaloid region septal nuclei, as well as fibers from the ventral tegmental area.