This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Anaesthesia
Increased requirement of curare – 
Select and explain. 
A. Ketamine, B. Althesin, C. Nitrous oxide, D. Histotoxic hypoxia
A: Ketamine
Answer: A: Ketamine 
Explanation: Ketamine increases muscle tone → dose of muscle relaxant may require an increment.