This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Surgery
Familial polyposis coli is due to 
Select and explain. 
A. Abnormality of chromosomes five, B. Abnormality of chromosomes, C. Intestinal tuberculosis, D. Intussusception
A: Abnormality of chromosomes five
Answer: A: Abnormality of chromosomes five 
Explanation: .desmoid tumour is often associated with the familial polyposis colon (FAP), osteomas, odontomes epidermal cysts-- Gardner's syndrome.it is usually due to genetic abnormality involving chromosome 5. ref:SRB&;s manual of surgery ,ed 3,pg no 776