This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Dental
Tzank smear in a case of pemphigus vulgaris show 
Select and explain. 
A. Acantholytic cells, B. Macrophages, C. Fibroblasts, D. Neutrophils
A: Acantholytic cells
Answer: A: Acantholytic cells 
Explanation: Cytodiagnosis is of most value in pemphigus and its various forms. Acantholysis is the loss of intercellular connections, such as desmosomes, resulting in loss of cohesion between keratinocytes, seen in diseases such as pemphigus vulgaris. It is absent in bullous pemphigoid, making it useful for differential diagnosis In bulbous pemphigoid, eosinophils are commonly seen. Ref Harrison 20th edition pg 1245