This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Screening, Subject name: Social & Preventive Medicine
Two screening tests in series will increase 
Select and explain. 
A. Sensitivity alone, B. Specificity alone, C. Both Sensitivity and Negative predicative value, D. Both Specificity and Positive predicative value
D: Both Specificity and Positive predicative value
Answer: D: Both Specificity and Positive predicative value 
Explanation: Condition 1 Condition 2 Test A,B,C,D,E (Screening Test in series ) Test A | B | C | D | E ** | Specificity & PPV | Sensitivity & NPV (Screening test in Parallel) (Together) * | A B C D E (Together) ** | Sensitivity & NPV | Specificity & PPV