This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Salivary Gland, Subject name: Surgery
True regarding Sjogren's syndrome are all of the following except: 
Select and explain. 
A. Autoimmune condition, B. Males are commonly affected, C. Progressive destruction of lacrimal and salivary gland, D. No single laboratory investigation is pathognomonic
B: Males are commonly affected
Answer: B: Males are commonly affected 
Explanation: Ans. (b) Males are commonly affectedRef: Bailey 261e p737Sjogren's Syndrome:* Most common in women* Chronic disease characterized by dry eyes, dry mouth (xerostomia) due to immunological destruction of Lacrimal and Salivary glands* Rheumatoid arthritis is commonly associated.* Characterized by lymphocytic infiltration of salivary and lacrimal glands.* Antibodies - SS-A and SS-B are seen in 90%* Parotid enlargement is seen in >50% cases* Lip biopsy is used to diagnose this syndrome (by examining minor salivary glands)