This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Dental
Multinucleate giant cells are seen in Tzanck smear in 
Select and explain. 
A. VZV, B. Bullous pemphigoid, C. Toxic epidermal necrolysis, D. Pemphigus
A: VZV
Answer: A: VZV 
Explanation: In viral infections, Tzanck test shows multinucleated giant cells ("Tzanck cells") in center. Tzanck smear, is scraping of an ulcer base to look for Tzanck cells. It is sometimes also called the chickenpox skin test and the herpes skin test, varicella zoster virus skin test. Ref Harrison 20th edition pg 1256