This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Niacin must be used in diabetics cautiously because 
Select and explain. 
A. It causes hypoglycemia, B. It impairs Insulin sensitivity, C. Increases metabolism of oral hypoglycemic agents, D. It increases skin thickness
B: It impairs Insulin sensitivity
Answer: B: It impairs Insulin sensitivity 
Explanation: Niacin can result in Insulin resistance and lead to hyperglycemia. Hence, it must be used cautiously in Diabetics.