This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
Estrogen administration in a menopausal woman increase the: 
Select and explain. 
A. Gonadotropin secretion, B. LDL cholesterol, C. Muscle mass, D. Bone mass
D: Bone mass
Answer: D: Bone mass 
Explanation: Postmenopausal women run a high-risk fr fracture of bones due to osteoporosis. PTH and IL-1 are involved. Estrogen prevents osteoporosis by inhibiting postdoc mastic activity and inhibits release of IL-1 by monocytes.
Increases absorption of calcium from the gut stimulates calcitonin secretion from C cells of thyroid and increases 1,25-dihydroxyvitamin D. All these lead to increased bone mineralisation