This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hypeension, Arrhythmias, Dyslipidemia, Subject name: Pharmacology
The antihypeensive agent that should be avoided in young females and is used topically to treat alopecia is: 
Select and explain. 
A. Hydralazine, B. Prazosin, C. Minoxidil, D. Indapamide
C: Minoxidil
Answer: C: Minoxidil 
Explanation: Minoxidil is a powerful vasodilator Active metabolite of minoxidil is an opener of ATP sensitive K channels; causes vasodilatation by hyperpolarizing smooth muscle. Minoxidil is avoided in young females because it causes Hirsutism. Drugs causing Hirsutism: Phenytoin Cyclosporine Minoxidil USE OF MINOXIDIL IN ALOPECIA - Hirsutism was observed as side effect of oral minoxidil. Applied topically it promotes hair growth in male pattern baldness and in alopecia areata.