This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
During acclimatization to high altitude all of the following take place except 
Select and explain. 
A. Increase in minute ventilation, B. Increase in the sensitivity of central chemoreceptors, C. Increase in the sensitivity of carotid body to hypoxia, D. Shift in the oxygen dissociation curve to the left
D: Shift in the oxygen dissociation curve to the left
Answer: D: Shift in the oxygen dissociation curve to the left 
Explanation: At high altitude there can be acute changes and changes due to acclimatization.
Acute mountain sickness

Dyspnoea, dizziness, tiredness, tachycardia, palpitation, nausea, vomiting etc.
At higher altitudes- pulmonary edema and cerebral edema may occur.

Acclimatization changes

Hyperventilation leading to respiratory alkalosis
Increased 2,3DPG- Hb-O2 dissociation curve shifts to right.
Increased erythropoietin leading to absolute polycythemia
Increased renal excretion of bicarbonate
Increased tissue vascularity
Increased oxidative metabolism
Increased diffusion capacity of lung
Increased myoglobin