This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Breast Cancer - Prognosis and Follow-Up, Subject name: Surgery
The most important prognostic factor in carcinoma breast is: 
Select and explain. 
A. Size of tumour, B. Skin involvement, C. Involvement of muscles, D. Axillary gland involvement
D: Axillary gland involvement
Answer: D: Axillary gland involvement 
Explanation: Ans: d (Axillary gland involvement)Ref: Patho Robbins, 7th ed, p. 1146 & 6th ed, p. 115, Schwartz surgery, 7th ed, p. 558, Bailey & Love, 24th ed, p. 839 & 23rd ed, p. 765