This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Biochemistry
C terminal end of androgen receptor is concerned with 
Select and explain. 
A. Ligand binding, B. Increasing biological half life, C. Increasing the affinity of receptor to DNA, D. Increasing the level of transcription
A: Ligand binding
Answer: A: Ligand binding 
Explanation: Activation function 2 (AF-2), responsible for agonist-induced activity (activity in the presence of bound agonist)Ref: DM Vasudevan, 7th edition, page no: 669