This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General surgery, Subject name: Surgery
Murphy's sign is seen in 
Select and explain. 
A. Acute cholecystitis, B. Cholangiocarcinoma, C. Cholangitis, D. Periampullary cancer
A: Acute cholecystitis
Answer: A: Acute cholecystitis 
Explanation: In the acute cholecystitis, the patient may have right upper quadrant tenderness that is exacerbated during inspiration by the examiner's right subcostal palpation (Murphy's sign). A positive Murphy's sign suggests acute inflammation and may be associated with a leukocytosis and moderately elevated liver function tests.Ref: Bailey and love 27e pg: 1199