This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Disorders of Carbohydrate Metabolism, Subject name: Pediatrics
Patient with growth retardation, delayed milestones with kinky hair. What is the diagnosis? 
Select and explain. 
A. Menke's disease, B. Trisomy 21, C. Lesch nyhan syndrome, D. Wilson disease
A: Menke's disease
Answer: A: Menke's disease 
Explanation: The given scenario suggests diagnosis of Menke's disease X- linked recessive disorder caused by mutations in genes coding for the copper transpo protein ATP7A. C/F- Growth retardation Delayed milestones Kinky hair Hypotonia, hypothermia Seizures Lesch nyhan syndrome- self injury Wilson disease- KF ring, neurological & hepatic manisfestation.