This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Diabites & Inappropriate Antidiuretic Hormone, Subject name: Medicine
Best drug to be used in obese type 2 diabetes meiiitus patient? 
Select and explain. 
A. Metformin, B. Glipizide, C. Pioglitazone, D. Exenatide
A: Metformin
Answer: A: Metformin 
Explanation: Ans. (a) MetforminRef.: Harrison 19th ed. / 2413-14* Drug of choice for obese type 2 diabetes mellitus is metformin. This drug increases the peripheral utilization of sugar by sensitizing the receptors. The fall in HbAlc is 1-2%.