This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Pediatrics
A 3-year-old child has presented with abdominal lump and aniridia shown below. All genes are responsible for development of this condition except? 
Select and explain. 
A. WT1, B. P53, C. Beta-catenin, D. K-ras
D: K-ras
Answer: D: K-ras 
Explanation: Ans. (d) K-ras gene.GeneWilms tumor characteristicFrequencyWT1Inselected-20%P-cateninUnselected-15% Tumors with WT1 mutations (-20% of total)-50%p53Anaplastic histology (-5% of total)-80% Image Source: