This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Definitive laboratory diagnosis of acute pancreatitis is done by: 
Select and explain. 
A. Serum Amylase, B. Serum Lipase, C. Hyperglycemia, D. Hypercalcemia
B: Serum Lipase
Answer: B: Serum Lipase 
Explanation: Answer is B (Serum Lipase) Serum lipase elevation is the most specific laboratory test for establishing a diagnosis of Acute Pancreatitis `A three fold elevated serum lipase value is usually diagnostic of acute pancreatitis' - Harrison Serum Lipase levels and serum amylase levels are both used to establish the diagnosis of acute pancreatitis An elevated serum Lipase level is more specific for pancreatitis than- a serum amylase level because many other pathologic conditions may present with an elevated amylase level. Serum lipase is therefore the single best answer of choice.