This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
IL -1 produces - 
Select and explain. 
A. T lymphocyte activation, B. Delayed wound healing, C. Increased pain perception, D. Decreased PMN release from bone marrow
A: T lymphocyte activation
Answer: A: T lymphocyte activation 
Explanation: Ans. is 'a' i.e., T-Iymphocyte activation . Also known as leucocyte activating factor (LAF) or B cell activating factor (BAF). . Principally secreted by macrophages and monocytes; and epithelial cells. . Other sources are B lymphocytes, fibroblasts and endothelial cells. . Immunological effects? - Activation of T cells for the production of IL - 2. - B cell proliferation and antibody synthesis - Neutrophil chemotaxis and increased PMN release from bone marrow. - Increases body temperature (impoant endogenous pyrogen). - Bone marrow cell proliferation - Induction of acute phase protein.