This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Dental
Antibiotic that can be used as  antiplaque agent is/are: 
Select and explain. 
A. Penicillin., B. Vancomycin., C. Kanamycin., D. All of the above.
D: All of the above.
Answer: D: All of the above. 
Explanation: Penicillin, vanomycin, kanamycin have been used as antiplaue agents but their use has been considerably reduced due to bacterial resistance and hypersensitivity reactions.