This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Pharmacology
all the following drugs are central antagonist drugs used in opiod dependency except ? 
Select and explain. 
A. nalaxone, B. nalmefene, C. naldemedine, D. naltraxone
C: naldemedine
Answer: C: naldemedine 
Explanation: Opioid Antagonists * Naloxone is an example of a opioid antagonist. * It is administered intravenously. * It can rapidly produce the withdrawal symptoms associated with opioid addiction. * Naltrexone is another example of an opioid antagonist. It is more potent than Naloxone and is used i the treatment of alcohol addiction but its mechanism in this treatment is unknown. PERIPHERAL ANTAGONISTS NALOXEGOL ALVIMOPAN NALDEMEDINE (PAMORA). ref : kd tripathi 8th ed