This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Malabsorbtion Syndrome, Subject name: Medicine
Gluten sensitive enteropathy is strongly associated with: 
Select and explain. 
A. Blood group B, B. HLA-DQ3, C. HLA-DR4, D. HLA-DQ2
D: HLA-DQ2
Answer: D: HLA-DQ2 
Explanation: Gluten enteropathy/Celiac Sprue It is associated with HLA -DQ2 Due to auto Ab against brush border epithelium which is present in the gut mucosa Clinical Feature-Osmotic diarrhoea Auto ab: Anti tissue transglutaminase Ab - Screening test Small intestinal mucosal Biopsy - Confirmatory test Treatment: No 'BROW'(Barley, Rye, Oats, Wheat) Only maize is allowed