This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Gestational Trophoblastic Disease, Subject name: Gynaecology & Obstetrics
Hydatidiform mole is characterized histologically by: 
Select and explain. 
A. Hyaline membrane degeneration, B. Hydropic degeneration of the villous stroma, C. Nonproliferation of cytotrophoblast, D. Nonproliferation of syncytiotrophoblast
B: Hydropic degeneration of the villous stroma
Answer: B: Hydropic degeneration of the villous stroma 
Explanation: Ans. is b, i.e. Hydropic degeneration of the villous stromaRef. Dutta Obs. 7/e, p 191Pathological features of H moleNaked eye appearance* Uterus is filled with multiple clusters of grape like cysts.Q* No trace of embryo/amniotic sac.* Marked proliferation of synctio and cyto trophoblast* Marked thinning of stromal tissue due to hydropic degeneration.* Absence of blood vessels* Villous pattern is maintained.Q