This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
In Sickle Cell Anaemia defect is in which chain: 
Select and explain. 
A. Alphachain, B. Beta chain, C. Both the chains, D. None of these
B: Beta chain
Answer: B: Beta chain 
Explanation: Beta chain