This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Skin
Ichthyosis linearis circumflexa is the characteristic skin lesion seen in: 
Select and explain. 
A. Netheon syndrome, B. Progeria, C. Lamellar ichthyosis, D. Harlequin ichthyosis
A: Netheon syndrome
Answer: A: Netheon syndrome 
Explanation: Netheon's syndrome (NS) is the most common of the ichthyosiform syndromes. It comprises erythroderma, hair shaft defects and atopic features. These patients develop recurrent crops of erythematous, scaly, migrating lesions with an incomplete double edge of peeling scale called ichthyosis linearis circumflexa. The pathognomonic feature of NS is the hair shaft defect known as trichorrhexis invaginata (TI) or ball and socket defect.