This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Mood Disorders, Subject name: Psychiatry
Esketamine, the drug that has been approved by FDA in 2019, has been approved for treatment of - 
Select and explain. 
A. Depression, B. Resistant schizophrenia, C. Bipolar disorder, D. Ketamine dependence
A: Depression
Answer: A: Depression 
Explanation: In 2019,FDA approved nasal spray of Esketamine It is an enantiomer of ketamine Given as a nasal spray under the practitioner's supervision. used for TRD(treatment resistant depression) Given with oral antidepressants.