This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
One of the following is not included in the major criteria for rheumatic hea disease? 
Select and explain. 
A. Ahritis, B. Carditis, C. Erythema marginatum, D. Raised ASLO titer
D: Raised ASLO titer
Answer: D: Raised ASLO titer 
Explanation: Guidelines of diagnosis used by the American Hea Association include major and minor criteria (ie, modified Jones criteria). In addition to evidence of a previous streptococcal infection, the diagnosis requires 2 major Jones criteria or 1 major plus 2 minor Jones criteria. Major criteria are as follows: Carditis, Migratory polyahritis, Subcutaneous nodules (ie, Aschoff bodies), Erythema marginatum, Chorea (also known as Sydenham chorea and "St Vitus dance"). Minor criteria are as follows: Clinical findings include ahralgia, fever, and previous history of ARF. Laboratory findings include elevated acute-phase reactants (eg, erythrocyte sedimentation rate, C reactive protein), a prolonged PR interval, and suppoing evidence of antecedent group A streptococcal infections (ie, positive throat culture or rapid streptococcal screen and an elevated or rising streptococcal antibody titer).