This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Pathology
The following is not a feature of malignant transformation by cultured cells 
Select and explain. 
A. Increased cell density, B. Increased requirement for growth factors, C. Alteration of cytoskeletal structures, D. Loss of anchorage
B: Increased requirement for growth factors
Answer: B: Increased requirement for growth factors 
Explanation: Malignant cells do not require stimulation by growth signals. they have capacity to proliferate without it.