This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Blood Vessels, Subject name: Pathology
Which among the following is ANCA negative? 
Select and explain. 
A. Wegener's granulomatosis, B. Microscopic polyangitis, C. Polyarteritis nodosa, D. Churg-Strauss syndrome
C: Polyarteritis nodosa
Answer: C: Polyarteritis nodosa 
Explanation: Ans: c (PAN) Ref: Robbins, 7th ed, p. 539 & Harrison, 16th ed, p. 2002"PAN has no association with ANCA"More about PAN:* Vasculitis of medium sized/small muscular arteries sparing pulmonary circulation* Characteristic -- All stages of inflammation coexist in different vessels.Microaneurysms (< 1 cm) - but not pathognomonic* 30% patients have hepatitis B Ag in their serum* MC organ system involved -- musculoskeletal > renal* MC cause of death -- gastrointestinal* Involvement of venules is suggestive of microscopic polyangitis