This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
Absolute contraindication to Hormone replacement therapy 
Select and explain. 
A. Osteoporosis, B. Otosclerosis, C. Colon cancer, D. Premature menopause
B: Otosclerosis
Answer: B: Otosclerosis 
Explanation: Absolute conrtraindications to HRT

Suspected pregnancy
Breast cancer
Endometrial cancer
Active liver disease
Known thrombophilia
Osteosclerosis.