This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Contraception, Subject name: Gynaecology & Obstetrics
DMPA causes all the following Except 
Select and explain. 
A. Weight gain, B. Irregular cycles, C. Amenorrhoea, D. Thromboembolism
D: Thromboembolism
Answer: D: Thromboembolism 
Explanation: Depomedroxyprogesterone AcetateDMPA, a suspension of microcrystals of a synthetic progestin. The regimen of 150 mg every 3 months is highly effective, producing pregnancy rates ofabout 0.3 per 100 women per year.The most impoant medical reason women discontinue use of DMPA and other progestin-only methods is persistent irregular vaginal bleeding. Eventually, total amenorrhea develops in most women who take DMPA; with continued administration, amenorrhea develops in 50% of women by 1 year and in 80% by 3 years.Ref: Berek and Novak&;s Gynecology; 15th edition; Chapter 10