This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: New Born Infants, Subject name: Pediatrics
Postoperative apnoea in the neonates is due to 
Select and explain. 
A. Over dose of relaxant, B. Overdose with inhalation agent, C. Concurrent aminoglycoside antibiotics, D. All of the above
D: All of the above
Answer: D: All of the above 
Explanation: (All of the above) (499-Lee 's anaesthesia 12th)Causes of post operative apnoea in the neonates are1. Immaturity2. Hypothermia 34 C or below3. Overdose of relaxant4. Overdose with inhalation agent5. Potentiation of non-depolarizing relaxant by volatile anaesthetic agents6. Concurrent aminoglycoside antibiotics7. Overdose of opioid analgesics8. A combination of the abvoeIndication for intubation of the neoborn and short term intermittent positive-pressure ventilation-546-Lees1. Central cyanosis for more than 3 min2. Bradycardia less than 100 bpm for more than 3 minutes3. Apnoea for more than 3 min4. 'White asphyxia' i.e. skin vasoconstriction5. Cardiac arrest or depression6. Apgar score of 0-2