This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Duration of action of omeprazole is - 
Select and explain. 
A. 1-2 hrs, B. 4-8 hrs, C. 8-16 hrs, D. 24-48 hrs
D: 24-48 hrs
Answer: D: 24-48 hrs 
Explanation: Ans. is 'd' i.e., 2448 hrs o These drugs have a sho half life of about 1.5 hours, however, the duration of action lasts for 24 to 48 hours due to the irreversible inactivation of the proton pump Until new proton pumps are synthesized and incorporated into the luminal membrane of parietal cells.