This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General Pharmacology, Subject name: Pharmacology
All of the following drugs act on ionic channels except: 
Select and explain. 
A. Nicotine, B. Insulin, C. Glibenclamide, D. Diazepam
B: Insulin
Answer: B: Insulin 
Explanation: Ans. B. Insulina. insulin acts on enzymatic (tyrosine kinase) receptorsb. Nicotine acts on NM and NN receptors which are ion channel receptorsc. Diazepam acts on GABA-BZD-Cl channel complex that mediates entry of chlorided. Glibenclamide is a sulfonylurea that acts on ACh sensitive K+ channels.