This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Pathology
case history of peripheral smear is showing hypersegmented neutrophils , this is due to deficiency of 
Select and explain. 
A. vit B12 deficiency, B. folate deficiency, C. iron deficiency, D. thalasemia
A: vit B12 deficiency
Answer: A: vit B12 deficiency 
Explanation: Neutrophil hypersegmentation can be defined as the presence of neutrophils whose nuclei have six or more lobes or the presence of more than 3% of neutrophils with at least five nuclear lobes. ... The presence of hypersegmented neutrophils is an impoant diagnostic feature of megaloblastic anaemias. ref : robbins 10th ed