This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Autonomic nervous system, Subject name: Pharmacology
The main mechanism of hyperpyrexia induced by atropine is? 
Select and explain. 
A. Vasodilation, B. inhibition of sweating, C. Through central actions, D. Increase in basal metabolic rate
B: inhibition of sweating
Answer: B: inhibition of sweating 
Explanation: Ref:KD Tripathi pharmacology 7th edition (page.no: 115) Rise in body temperature by Atropine occurs at higher doses. It is due to both inhibition of sweating as well as stimulation of temperature regulating centre in the hypothalamus.