This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Medicine
Use of spironolactone in liver cirrhosis is 
Select and explain. 
A. Decrease edema, B. Improves liver function, C. Decrease afterload, D. Decrease intravascular volume
A: Decrease edema
Answer: A: Decrease edema 
Explanation: Spironolactone(aldosterone antagonist) - potassium sparing diuretic is staed as a Single dose of 100-200mg/day,in cirrhotic patients who have peripheral edema . In moderate ascites, Spironolactone is given along with furosemide . Side effects -gynecomastia is an impoant side effect ,amiloride can be alternatively used in place of Spironolactone. Ref:Harrison 20 th edition pg no 2412