This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
All of the following variables can predict survival in a patient with primary sclerosing cholangitis; except 
Select and explain. 
A. Serum bilirubin level, B. Splenomegaly, C. Presence of AMA (Antimitochondrial antibody) in high titre, D. Histologic stage
C: Presence of AMA (Antimitochondrial antibody) in high titre
Answer: C: Presence of AMA (Antimitochondrial antibody) in high titre 
Explanation: Primary sclerosing cholangitis
The prognosis is unfavorable, with a median survival of 9 to 12 years following the diagnosis, regardless of therapy.
Four variables (age, serum bilirubin level, histologic stage, and splenomegaly) predict survival.
The diagnosis is supported by a positive AMA test.
The presence of AMA in high titre is unrelated to the clinical or histologic picture.