This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
Which of the following is poor prognostic factor in a child with ALL ? 
Select and explain. 
A. Age 2–8 yrs, B. Total leucocyte count < 50,000, C. t (9; 22); t (4;11); t (1;19), D. Absent blasts in peripheral smear
C: t (9; 22); t (4;11); t (1;19)
Answer: C: t (9; 22); t (4;11); t (1;19) 
Explanation: None