This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Scleroderma, Subject name: Medicine
C.R.E.S.T syndrome is? 
Select and explain. 
A. Generalised scleroderma, B. Limited scleroderma, C. Localised scleroderma, D. Systemic sclerosis
B: Limited scleroderma
Answer: B: Limited scleroderma 
Explanation: C = Calcinosis R = Raynaud phenomenon E = Esophageal Dysmotility S = Sclerodactyly T = Telangiectasia (CREST Syndrome is example of Limited Scleroderma) Option C : Localized Scleroderma = Only skin involvement (Morphea) seen Scleroderma type Antibody Generalized Scleroderma Limited Scleroderma Anti-topoisomerase antibody Anti centromere antibody