This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Respiratory System Pa 3, Subject name: Physiology
Acclimatization does not include ? 
Select and explain. 
A. Hyperventilation, B. Decreased concentration of 2,3-DPG in RBC, C. Increased erythropoiesis, D. Kidney excrete more alkali
B: Decreased concentration of 2,3-DPG in RBC
Answer: B: Decreased concentration of 2,3-DPG in RBC 
Explanation: Acclimatization refers to the: Respiratory alkalosis produced by the hyperventilation which shifts the O2 -Hb curve to the left, but there is also concomitant increase in red blood cell 2,3 DPG tends to decrease the O2 affinity of the hemoglobin the net effect is a small increase in P50 (right shift ) The decrease in O2 affinity makes more O2 available to the tissues. However,the value of the increase in P50 is limited because when the aerial Po2 is markedly reduced, the decreased O2 affinity also interferes with O2 uptake by hemoglobin in the lungs.