This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
The drug of choice in Chorio ' Carcinoma is: 
Select and explain. 
A. Methotrexate, B. Actinomycin-D, C. Vincristine, D. 6-thioguanine
A: Methotrexate
Answer: A: Methotrexate 
Explanation: Methotrexate