This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
The phenomenon where subsequent generations are at risk of earlier and more severe disease, is known as - 
Select and explain. 
A. Anticipation, B. Pleiotrophy, C. Imprinting, D. Mosaicism
A: Anticipation
Answer: A: Anticipation 
Explanation: . Anticipation