This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.V.S., Subject name: Pediatrics
In G6PD deficiency, which cells are more prone for hemolysis? 
Select and explain. 
A. Older red cells, B. Young red cells, C. Reticulocytes, D. All are susceptible
A: Older red cells
Answer: A: Older red cells 
Explanation: a. Older red cells(Ref: Nelson's 20/e p 2335, Ghai 8/e p 339)Because mature red cells do not synthesize new proteins, G6PD enzyme activity falls quickly to levels inadequate to protect against oxidant stress as red cells age. Thus, older red cells are much more prone to hemolysis than younger ones.