This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Biochemical abnormality associated with osteogenesis imperfecta is increase in: 
Select and explain. 
A. Alkaline phosphatase, B. Acid phosphatase, C. Bicarbonate ion, D. Phosphorylase enzyme
D: Phosphorylase enzyme
Answer: D: Phosphorylase enzyme 
Explanation: None