This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Acute osteomyelitis is most frequently caused by: 
Select and explain. 
A. Staphylococcus aureus, B. Staphylococcus albus, C. Staph. aureus + Staph. albus, D. None of the above
C: Staph. aureus + Staph. albus
Answer: C: Staph. aureus + Staph. albus 
Explanation: Acute osteomyelitis is usually a polymicrobial infection. Different types of organisms may be cultured from these lesions; the most common are Staphylococcus aureus and Staphylococcus albus, and various streptococci. Anaerobes such as Bacteroides, Porphyromonas or Prevotella species also predominate.
Ref: Shafer's textbook of oral pathology 7th edition page 493