This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Pharmacology
Drug of choice for Polycystic ovarian disease is 
Select and explain. 
A. Metformin, B. Estrogen, C. Estrogen and progesterone combination pill, D. Dopamine antagonist
C: Estrogen and progesterone combination pill
Answer: C: Estrogen and progesterone combination pill 
Explanation: Refer CMDT 2014/744 Oral contraceptives are used for the treatment of mennstrul irregularity These are the drug of choice for PCOD PCOD is also known as Stein-Levanthal syndrome. Weight loss by regular exercise low glycemic index diet combined with insulin lowering drugs like metformin can restore feility in 85 percnt of females For females who don't respond to weight loss, metformin therapy may be helpful