This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pharmacology
Which of the following is a serious adverse effect seen with zolendronate? 
Select and explain. 
A. Acute renal failure, B. Ventricular fibrillation, C. Peptic ulcer, D. Anterior uveitis
A: Acute renal failure
Answer: A: Acute renal failure 
Explanation: ADRS of bisphosphonates: gastric ulcer, renal failure, flu like syndrome, GERD, osteonecrosis of jaw Zolendronate is a Bishosphonate. (REF.Essential of medical pharmacology K D TRIPATHI 6 Edition, Page No - 335)