This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Which of the following drugs used to treat type-II diabetes mellitus causes weight loss 
Select and explain. 
A. Metformin, B. Glimepiride, C. Repaglinide, D. Gliclazide
A: Metformin
Answer: A: Metformin 
Explanation: Ans. is 'a' i.e., Metformin Effect of antidiabetic drugs on weight Increased : Sulfonylureas, insulin, pioglitazone Decreased : Metformin, GLP-1 antagonists, pramlinitide No effect: DPP-4 inhibitors