This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Gynaecology & Obstetrics
A major causal factor in some cases of hypogonadism is 
Select and explain. 
A. Reduced secretion of gonadotropin-releasing hormone (GnRH), B. Hypersecretion of pituitary LH and FSH as the result of increased GnRH, C. Excess secretion of testicular activin by Seoli cells, D. Failure of the hypothalamus to respond to testosterone
A: Reduced secretion of gonadotropin-releasing hormone (GnRH)
Answer: A: Reduced secretion of gonadotropin-releasing hormone (GnRH) 
Explanation: Reduced secretion of GnRH will result in extremely low levels of circulating LH and FSH, causing testicular atrophy, as in Kallmann's syndrome.