This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Von Geirke's occurs due to deficiency of ? 
Select and explain. 
A. Glucose-6-phosphatase, B. Liver Phosphorylase, C. Muscle phosphorylase, D. Debranching enzyme
A: Glucose-6-phosphatase
Answer: A: Glucose-6-phosphatase 
Explanation: Ans. is 'a' i.e., Glucose-6-phosphataseGlucose - 6- phosphatase is deficient in Von Gierke's disease.