This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hematology, Subject name: Pharmacology
A patient was taking warfarin and INR comes out to be 8. Next step would be to stop the drug and:- 
Select and explain. 
A. Resta at a lower dose once the INR is in therapeutic range, B. Give oral vitamin K1, C. Administer fresh frozen plasma, D. Transfuse fresh blood
B: Give oral vitamin K1
Answer: B: Give oral vitamin K1 
Explanation: Management of warfarin overdose is done as follows: *INR < 5 but above therapeutic range - Discontinue warfarin temporarily and resta at low dose. *INR 5-9 - Vitamin K1 (1 mg oral) *INR > 9 but no bleeding - Vitamin K1 (2 - 3 mg oral) *INR > 20 or bleeding - Four factor prothrombin complex or Fresh frozen plasma.