This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of carbohydrate, Subject name: Biochemistry
Lysosomal a1 - 4 and a1 - 6 glucosidase deficiency is seen in 
Select and explain. 
A. Von Gierke disease, B. Cori disease, C. Pompe disease, D. Tarui disease
C: Pompe disease
Answer: C: Pompe disease 
Explanation: Type Name Enzyme Deficiency Clinical Features II Pompe disease Lysosomal a1 - 4 and a1 - 6 glucosidase (acid maltase) Accumulation of glycogen in lysosomes: juvenile onset variant, Muscle hypotonia, Death from hea failure by age 2 Adult-onset variant, muscle dystrophy Reference: Harper; 30th edition; Table: 18-2; Page no: 179