This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Central Nervous system, Subject name: Pharmacology
All of the following can be used to treat heroin dependence except: 
Select and explain. 
A. Disulfiram, B. Buprenorphine, C. Clonidine, D. Lofexidine
A: Disulfiram
Answer: A: Disulfiram 
Explanation: Ref: Goodman and Gilman 12th/660-661 *Disulfiram is used for alcohol de-addiction and not for opioid. *Methadone or Buprenorphine are used to prevent withdrawal symptoms. *Alpha 2 Agonists like clonidine and lofexidine are used to treat sympathetic withdrawal symptoms of opioid addiction.