This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Defect in folding of the protein result in which of the following clinical disease: 
Select and explain. 
A. Kuru, B. Migraine, C. Hypothyroidism, D. Myopia
A: Kuru
Answer: A: Kuru 
Explanation: A i.e. Kuru