This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Papulosquamous Disorders, Subject name: Skin
Which hormone is responsible for acne - 
Select and explain. 
A. Estrogen, B. Thyroid, C. Testosterone, D. Gonadotropins
C: Testosterone
Answer: C: Testosterone 
Explanation: Ans. is 'c' i.e., TestosteronePredisposing factors for Acne vulgariso Genetic factorso Hormones - Androgens, glucocorticoids,o Psychological stress and depression,o Environmental factors - High temperature & humidity,o Cosmetics - Containing lenolin, petroleum, vegetable oils,o Infection - Propionibacterium, Pityrosporum, Staph, epidermidis.o Menstural cycle - Premenstural aggravation,o Hyperkeratosis of pilosebaceous ostia.o Drugs - Antepileptics (Carbamazepine, phenytoin, phenobarbitone), antitubercular (INH, rifampin, ethionamide), antidepressants, cyclosporine,Vitamin B12, Cough syrups containing halogens (Iodides, bromides).