This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Medullary carcinoma of Thyroid is characterized by all, except - 
Select and explain. 
A. Hereditary in nature, B. Hormone dependent, C. Secretes Calcitonin, D. Amyloid stroma is seen
B: Hormone dependent
Answer: B: Hormone dependent 
Explanation: Medullary carcinoma thyroid 

Accounts for approximately 7% of malignant tumour of the thyroid.
It arises from ultimobranchial bodies (from the parafollicular C cells derived from neural crest and not from thyroid follicles).
It contains amyloid stroma
Familial medullary carcinoma occurs in 25% of patients (Marfanoid habitus, Amyloidosis and Hirschsprung's disease also occur in patients with familial medullary cancer).
Medullary carcinoma occurs in association with (MEN) syndrome.
All patients with medullary carcinoma of thyroid should be screened for RET point mutation on chromosome 10.
Medullary Ca thyroid secretes calcitonin, this cause hypocalcemia. Calcitonin also acts as tumour marker.
Involvement of the lymph node is very common in medullary carcinoma. It is seen in 50-60% of cases.