This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Infectious disease, Subject name: Pediatrics
The most effective method of reduction of incidence of institutional pediatric staphylococcus aureus infection is __________ 
Select and explain. 
A. Mask and gloves use with each suspected patient, B. Meticulous handwashing before and with patients, C. Treatment of all culture Positive patients with vancomycin, D. Routine isolation of culture Positive
B: Meticulous handwashing before and with patients
Answer: B: Meticulous handwashing before and with patients 
Explanation: S.aureus is transmitted primarily by direct contact. Strict attention to handwashing techniques is the most effective measure for preventing the spread of staphylococci from one individual to another. Use of a hand wash containing chlorhexidine or alcohol is recommended. Reference: Nelson textbook of pediatrics 19th edition Page 908