This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Fulvestrant is used in the treatment of 
Select and explain. 
A. HR positive metastatic breast cancer in post menopausal women, B. Male breast cancer, C. Paget's disease, D. Acute myeloid leukemia associated with Down's syndrome
A: HR positive metastatic breast cancer in post menopausal women
Answer: A: HR positive metastatic breast cancer in post menopausal women 
Explanation: Fulvestrant is a selective estrogen receptor downregulator (SERD) used in cases of hormone receptor positive metastatic breast carcinoma in post menopausal women.