This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
Spermicidal jelly acts through : 
Select and explain. 
A. Acrosomal enzyme, B. Cervical enzyme alteration, C. Glucose uptake inhibition by sperms, D. Disruption of cell membrane
D: Disruption of cell membrane
Answer: D: Disruption of cell membrane 
Explanation: Ans. is d i.e Disruption of cell membrane Spermicides : "Spermicides are contraceptive chemical agents. They comprise,of a chemical capable of destroying sperm, incororated into an ine base. The commonly used spermicidal agents contgain nonionic surfactants which alter sperm surface membrane permeability, causing osmotic changes resulting in killing of sperm. Most of the spermicides contain nonoxynol-9 which is the best for this purpose."