This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Mood Disorders, Subject name: Psychiatry
Tricyclic antidepressant are contraindicated in: 
Select and explain. 
A. Glaucoma, B. Brain tumor, C. Bronchial asthma, D. Hypeension
A: Glaucoma
Answer: A: Glaucoma 
Explanation: Due to anticholinergic action, TCAs should be avoided in glaucoma These agents block muscarinic acetylcholine receptors, resulting in anticholinergic effects (e.g., dry mouth, blurred vision, urine retention, constipation); they are contraindicated in patients with glaucoma.