This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
A 5 year old child presented with periorbital swelling and oliguria. Nephrotic syndrome is suspected. Which of the following is the commonest type of nephrotic syndrome in this child? 
Select and explain. 
A. Minimal change disease, B. Chronic glomerulonephritis, C. Hemolytic uremic syndrome, D. Congenital nephrotic syndrome
A: Minimal change disease
Answer: A: Minimal change disease 
Explanation: Minimal change disease (MCD), sometimes known as nil lesion, causes 70-90% of nephrotic syndrome in childhood but only 10-15% of nephrotic syndrome in adults. Affected patients are generally younger than age 6 years at onset. Typically, periorbital swelling and oliguria are noted, often following an influenza-like syndrome. Minimal change disease on renal biopsy shows no obvious glomerular lesion by light microscopy and is negative for deposits by immunofluorescent microscopy. Ref: Lewis J.B., Neilson E.G. (2012). Chapter 283. Glomerular Diseases. In D.L. Longo, A.S. Fauci, D.L. Kasper, S.L. Hauser, J.L. Jameson, J. Loscalzo (Eds), Harrison's Principles of Internal Medicine, 18e.