This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
HLA is present on – 
Select and explain. 
A. Short arm of chromosomes 6, B. Short term of chromosomes 3, C. Long arm of chromosomes 3, D. Long arm of chromosomes 6
A: Short arm of chromosomes 6
Answer: A: Short arm of chromosomes 6 
Explanation: o HLA complex (MHC) gene is located on the short arm of chromosome 6.
o The histocompatibility antigens (human leukocyte antigens - HLA) are cell surface antigens that induce
an immune response leading to the rejection of allografts.
o The principal physiologic function of the cell surface histocompatibility molecules is to bind peptide
fragments of foreign proteins for presentation to antigen-specific T cells.
o The histocompa