This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Structure and function of protein, Subject name: Biochemistry
Co-translational inseion is seen with 
Select and explain. 
A. Translocon, B. Chaperons, C. Ubiquitin, D. Mannose 6- P
A: Translocon
Answer: A: Translocon 
Explanation: The signal hypothesis states that protein is inseed into ER membrane at the same time its mRNA being translated on polyribosomes known as " co-translational inseion ". This is translocation endoplasmic reticulum. Components: N terminal signal peptide: Polyribosomes SRP SRP-R Sec 61 translocon TRAM TRAP proteins Reference: Harper; 30th edition