This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy: General Principles, Subject name: Pharmacology
Imatinib primarily acts by inhibiting: 
Select and explain. 
A. BCR-ABL, B. Tyrosine kinase, C. PGDFR, D. None
B: Tyrosine kinase
Answer: B: Tyrosine kinase 
Explanation: Ans. (B) Tyrosine kinase(Ref: KDT 8th/e p929)Imatinib inhibits tyrosine kinase linked withabl-bcr fusionPDGF receptorc-kit receptor