This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Curshmann's crystals are seen in ? 
Select and explain. 
A. Bronchial asthma, B. Bronchiectasis, C. Chronic bronchitis, D. Wegners granulomatosis
A: Bronchial asthma
Answer: A: Bronchial asthma 
Explanation: Ans. is 'a' i.e., Bronchial asthma Pathology of Asthma Gross ? Lungs are overdistended because of overinflation and there may be small area of atelactasis. The most striking macroscopic finding is occlusion of bronchi and bronchioles by thick tenacious mucus plugs. Histology ? Characterized by presence of numerous eosinophils and neutrophils. Curschman spiral - Whorls of shed epithelium in mucus plugs. Charcot -leyden crystals - Collection of crystalloids made up of eosinophilic membrane protein. The other characteristic histological finding of Asthma is collectively called Airway remodelling, it includes - Thickening of the basement membrane of the bronchial epithelium. Edema and an inflammatory infiltrate in the bronchial walls with a prominence of eosinophils and mast cells. An increase in the size of submucosal glands. Hyperophy of bronchial wall muscle. The "airway remodelling" contributes to airflow obstruction.