This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous (Pharmacology), Subject name: Pharmacology
Arrange the following drugs according to their half life in increasing order1. Amiodarone2. Adenosine3. Esmolol4. Omeprazole 
Select and explain. 
A. 2, 3, 4, 1, B. 2, 3, 1, 4, C. 3, 2, 4, 1, D. 2, 4, 2, 1
A: 2, 3, 4, 1
Answer: A: 2, 3, 4, 1 
Explanation: Ans. AExplanation:* Amiodarone is longest acting anti-arrhythmic drug. Its half life is more than 3 weeks.* Adenosine is shortest acting anti-arrhythmic drug having half life less than 10 seconds.* Esmolol is an ultra short acting beta blocker. It is metabolized by pseudocholinesterase and thus has half life less than 5 minutes.* Omeprazole has half life of 1 -2 hours but works for 24 hours due to irreversible inhibition of proton pump.* Thus, the sequence isAdenosine < Esmolol < Omeprazole < Amiodarone