This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Respiratory system, Subject name: Physiology
Increased oxygen delivery to tissues in response to increased CO2 is 
Select and explain. 
A. Bohr effect, B. Haldane effect, C. Hamburger effect, D. Chloride shift
A: Bohr effect
Answer: A: Bohr effect 
Explanation: The Bohr effect is a physiological phenomenon first described in 1904 by the Danish physiologist Christian Bohr: hemoglobin's oxygen binding affinity is inversely related both to acidity and to the concentration of carbon dioxide Ref: guyton and hall textbook of medical physiology 12 edition page number:353,354,355