This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pharmacology
Osteoporosis is a major adverse effect caused by the glucocorticoids. It is due to their ability to(Lippincott's 3rd pharmacology) 
Select and explain. 
A. Increases the excretion of calcium, B. Inhibit absorption of calcium, C. Stimulate the hypothalamic - pituitary adrenal axis, D. Decreases production of prostaglandins
B: Inhibit absorption of calcium
Answer: B: Inhibit absorption of calcium 
Explanation: B. i.e. (Inhibit absorption of calcium) (314- Lippincott's 3rd)Glucocorticoid- induced osteoporosis is attributed to inhibition of calcium absorption as well as bone formation.Increased intake of calcium plus vitamin D or calcitonin or of other drugs that are effective in this condition is indicated.Glucocorticoids suppress rather than stimulate the hypothalamic -pituitary- adrenal axis. The decreased production of prostaglandins does not play a role in bone formation.