This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General surgery, Subject name: Surgery
In an elective lap cholecystectomy with no gross spillage, antibiotics required are 
Select and explain. 
A. Single dose of Preoperative IV antibiotic followed by a 5 day course of oral antibiotics, B. Post operative IV antibiotics for 1 day followed by a 5 day course of oral antibiotics, C. Single dose of Preoperative IV antibiotic only, D. 5 day course of oral antibiotics only
C: Single dose of Preoperative IV antibiotic only
Answer: C: Single dose of Preoperative IV antibiotic only 
Explanation: Elective lap cholecystectomy is a clean-contaminated surgery, single preoperative IV antibiotic during decisive period is sufficientThere is no evidence that fuher doses of antibiotics after surgery are of any value in prophylaxis against infectionWhen wounds are heavily contaminated or when an incision is made into an abscess, a 5-day course of therapeutic antibiotics may be justifiedRef: Bailey and Love 27e pg: 53