This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Inhalational Anesthetic Agents, Subject name: Anaesthesia
Which of the following is most cardio depressant 
Select and explain. 
A. Halothane, B. Isoflurane, C. Sevoflurane, D. Desflurane
A: Halothane
Answer: A: Halothane 
Explanation: Halothane is direct myocardial depressant, decreases SA node activity and decreases hea rate. Also sensitizes the hea to the arrhythmogenic effectsof epinephrine and hence is contraindicated in pheochromocytoma. Isoflurane , sevoflurane and desflurane at required MAC does not cause much cardiac depression. They dilate the blood vessels and decreases the mean aerial pressure .