This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Pharmacology
Thiazide diuretics can be used for the treatment of all of these conditions EXCEPT 
Select and explain. 
A. Idiopathic hypercalciuria with nephrocalcinosis, B. Hyperlipidemia, C. Congestive Hea Failure, D. Hypeension
B: Hyperlipidemia
Answer: B: Hyperlipidemia 
Explanation: Thiazides cause hyperlipidemia as adverse effect and thus cannot be used to treat this condition. Indications of thiazides: Diuretic Uses: Non-diuretic Uses: Hypeension (First line drugs) Congestive hea failure Diabetes insipidus Idiopathic hypercalciurea with Nephrocalcinosis Loop diuretics cause hypocalcemia by increasing the excretion of Ca2+ whereas thiazides cause hypercalcemia by decreasing its excretion. Thiazides reduce the excretion of Ca++ in the kidney, so can be used for the treatment of patients with hypercalciuria and recurrent Ca++ stones in the kidney.