This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Sexuality and intersexuality, Subject name: Gynaecology & Obstetrics
46, XY chromosomal pattern with uterus and cervix but poorly developed breasts are seen in 
Select and explain. 
A. Swyer syndrome, B. Turner syndrome, C. Androgen insensitivity syndrome, D. Klinefelter syndrome
A: Swyer syndrome
Answer: A: Swyer syndrome 
Explanation: Complete Gonadal Dysgenesis (Swyer Syndrome)Swyer syndrome is an uncommon form of gonadal dysgenesis, characterized by a 46, XY karyotype.Despite the presence of a Y chromosome, the phenotype is female because the dysgenetic (streak) gonads produce neither AMH nor androgens. Consequently, the vagina, cervix, uterus, and fallopian tubes develop normally and the internal and external genitalia do not masculinize but due to hypoestrogenism breasts are poorly developed.Reference: Clinical gynecologic endocrinology; 10th edition; Chapter 9; Normal and Abnormal Sexual Development; Page no: 365