This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Which one of the following inhalational anesthetics is most likely to cause fluoride ion nephrotoxicity ? 
Select and explain. 
A. Methoxyflurane, B. Enflurane, C. Halothane, D. Isoflurane
A: Methoxyflurane
Answer: A: Methoxyflurane 
Explanation: Ans. is 'a' i.e., Methoxyflurane o Intrarenal metabolism of methoxyflurane and subsequent intrarenal production of fluoride ion is the significant cause of methoxyflurane renal toxicity.