This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
True statements are all, EXCEPT: 
Select and explain. 
A. Chromosome six harbours the gene for MHC, B. Genes encoding compliments are located adjacent to class I, C. Monocytes have MHC class II antigens on their surfaces, D. Class III MHC does not encode complement
D: Class III MHC does not encode complement
Answer: D: Class III MHC does not encode complement 
Explanation: Answer is D (Class III MHC does not encode complement): Class III MIIC encode complements of the component system. Genes coding for histocompatibility antigens are clustered on a small segment of chromosome 6. This cluster constitutes the Human MHC or Human Leucocytes Antigen (HLA) complex. Class I antigens: * are expressed on all nucleated cells and platelets.Q * encode cell surface glycoproteins.Q * they are encoded by three closely related loci HLA-A, HLA-B, HLA-C.Q * CD8 + T cells widely express Class I HLA antigens.Q Class II antigens: * are expressed on macrophages, B cells and T cells.Q * encode cell surface glycoproteins.Q * they have a single loci HLA-D (with three surface loci DR, DQ, DP).Q Class III antigens: * these encode complements of the complement system.Q Note: That class III molecules loci, are present in between the loci for class I and class II molecules, on the HLA complex. Thus they lie adjacent to both class I as well as class II molecules.()