This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Glomerular Filtration, Renal Blood Flow, and Their Control, Subject name: Physiology
What is implied, if a drug has more renal clearance than the GFR : 
Select and explain. 
A. Drug is reabsorbed in the tubules, B. Drug is secreted in the tubules, C. Drug is excreted in bile, D. Drug is neither secreted, nor resorbed.
B: Drug is secreted in the tubules
Answer: B: Drug is secreted in the tubules 
Explanation: Ans. is 'b' i.e. Drug is secreted in the tubules Logically, if a drug is more in renal clearance than the amount filtered by glomerulus, it has to be secreted in the kidney tubules." Tubular secretion - is the active transfer of organic acids and bases by two separate nonspecific mechanism which operate in the proximal tubules. If renal clearance of a drug is greater than 120 ml/min (g.f.r.), additional tubular secretion can be assumed to be occuring "Soif renal clearance is more than G.F.R.* - Tubular secretionIf renal clearance is less than G.F.R. * - Tubular reabsorption.If renal clearance is equal to G.F.R.* - The drug does not undergo either tubular sec. or tub. reabsorption.