This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Restriction fragment length polymorphism is used for 
Select and explain. 
A. Analysis of chromosomes structures, B. DNA estimation, C. Synthesis of nucleic acid, D. Detecting proteins in a cell
A: Analysis of chromosomes structures
Answer: A: Analysis of chromosomes structures 
Explanation: RFLP can be observed by cleaving the DNA into fragments with restriction enzymes. The length of the restriction fragments is altered if the genetic variant alters the DNA. It doesnot estimate DNA but detects variation in DNA structure. DNA is contained in chromosomes. RFLP also used to trace chromosomes from parents to offspring.