This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anaesthesia, Subject name: Pharmacology
Which of the following drug undergoes Hoffman's elimination? 
Select and explain. 
A. Atracurium, B. Pancuronium, C. Mivacurium, D. Vecuronium
A: Atracurium
Answer: A: Atracurium 
Explanation: Ans. (A) Atracurium(Ref: KDT 8th/e p380)Atracurium and cis-atracurium undergo Hoffmann's elimination (spontaneous non-enzymatic molecular rearrangement) and are the agents of choice for patients with hepatic or renal insufficiency.Atracurium is metabolized to laudanosine that is responsible for seizures. Cis-atracurium is relatively safe in this regard.