This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: NEET Jan 2020, Subject name: Medicine
What is differentiating feature between irritable bowel syndrome and inflammatory bowel disease is? 
Select and explain. 
A. pain in abdomen, B. Stool calprotectin, C. Mucus in stools, D. Diarrhoea
B: Stool calprotectin
Answer: B: Stool calprotectin 
Explanation: FECAL CALPROTECTIN, is a biomarker of bowel inflammation and help in differentiating from irritable bowel syndrome. Faecal lactoferrinis a highly sensitive and specific marker for detecting intestinal inflammation. Faecal calprotectinlevels correlate well with histologic inflammation, predict relapses, and detect pouchitis.