This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
In sickle cell anemia, the defect is in which chain - 
Select and explain. 
A. α-chain, B. β-chain, C. Both the chains, D. None of these
B: β-chain
Answer: B: β-chain 
Explanation: None