This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Medicine
Following investigations are required in initial evaluation of a chronic myeloid leukemia patient EXCEPT - 
Select and explain. 
A. Peripheral smear, B. Test for Philadelphia chromosome, C. Bone marrow testing, D. HLA typing
D: HLA typing
Answer: D: HLA typing 
Explanation: CML is established by identification of the clone of hematopoietic stem cells that possesses the reciprocal translocation between chromosome 9 & 22,forming Philadelphia chromosome. Peripheral smear shows metamyelocytes, myelocytes, mature segmented neutrophils , basophils.Bone marrow examination reveals hypercellularity with predominance of myeloid cells.Reference:Harsh mohan textbook of pathology sixth edition pg no 357