This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Pharmacokinetics, Subject name: Pharmacology
Dosage of drug is determined by following except- 
Select and explain. 
A. Volume of distribution, B. Half life, C. Lipid solubility, D. Excretion of drug
B: Half life
Answer: B: Half life 
Explanation: Ans. is 'None', but go with "b" as the best option here o Loading dose is governed by volume of distribution and volume of distribution is affected by lipid solubility.o Maintenance dose is governed by clearance (excretion) of drug and half life.o For one option go ahead for option b ie half life because :"Clearance is the most important factor for maintenance dose".------Katzung 10th/e - 44