This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetics, Subject name: Pathology
The following technique is used to analyze DNA obtained from cancer biopsies, in which tumor cells are often contaminated with large numbers of admixed stromal cells 
Select and explain. 
A. Sanger sequencing, B. Single base primer extension, C. Pyrosequencing, D. Amplicon length analysis
C: Pyrosequencing
Answer: C: Pyrosequencing 
Explanation: Ans. (c) Pyrosequencing(Ref: R 9th/pg 140; 8th/pg 140)Pyrosequencing:Highly sensitive than Sanger sequencing and can detect even 5% mutated DNAFor this reason, it is be used to analyze DNA obtained from cancer biopsies, in which tumor cells are often "contaminated" with large numbers of admixed stromal cells.