This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Sedative-Hypnotics and Parkinsonism, Subject name: Pharmacology
A patient was admitted to the emergency depament due to alcohol intoxication. 12 Hours after admission the patient began to show agitation and seizure like activities . The drug used In treatment acts by: 
Select and explain. 
A. Facilitate GABA by increasing frequency of chloride channel opening, B. Facilitate GABA action by increasing duration of chloride channel opening, C. 5HT antagonist, D. 5HT agonist
A: Facilitate GABA by increasing frequency of chloride channel opening
Answer: A: Facilitate GABA by increasing frequency of chloride channel opening 
Explanation: * The clinical scenario describes alcohol withdrawal symptoms. Treatment for alcohol withdrawal is benzodiazepine. Benzodiazepine works by increasing frequency of chloride channel opening.* Barbiturates work by increasing duration of chloride channel opening* 5HT antagonist are Serotonin inhibitors. Atypical anti-depressants work by inhibiting 5HT receptors* 5HT agonist are serotonin receptors stimulators. They are used in treatment of Migraine and anxiety