This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Condition shown in color plate can be seen in: 
Select and explain. 
A. Melkersson rosenthal syndrome, B. Down syndrome, C. Pierre Robin syndrome, D. Both 1 and 2
D: Both 1 and 2
Answer: D: Both 1 and 2 
Explanation: Fissured Tongue   
(Scrotal tongue, lingua plicata)
Fissured tongue is a condition frequently seen in the general population and it is characterized by grooves that vary in depth and are noted along the dorsal and lateral aspects of the tongue. Although a definitive etiology is unknown, a polygenic mode of inheritance is suspected because the condition is seen clustering in families who are affected. Patients are usually asymptomatic, and the condition is initially noted on routine intraoral examination as an incidental finding. Fissured  tongue  is  also  seen  in  Melkersson-Rosenthal syndrome and Down syndrome and in frequent association with benign migratory glossitis (geographic tongue).
Ref:Shafer’s Ed 7th Pg 26