This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Rifampin induces metabolism of which drug? 
Select and explain. 
A. Zidovudine, B. Lamivudine, C. Nevirapine, D. Enfuviide
C: Nevirapine
Answer: C: Nevirapine 
Explanation: Ans. is 'c' i.e., Nevirapine Rifampin Interactions Microsomal enzyme inducer - increases CYP 450 isoenzymes. It thus induces its own metabolism as well as metabolism of other drugs like warfarin, oral contraceptives, coicosteroids, sulfonylureas, HIV protease inhibitors, non nucleoside reverse transcriptase inhibitors (NNI), theophylline, metoprolol, fluconazole, ketoconazole, clarithromycin and phenytoin. Nevirapine is an NNI and thus its metabolism is induced by rifampin.