This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.N.S, Subject name: Medicine
All of the following are true regarding progressive multifocal leukoencephalopathy except 
Select and explain. 
A. Only manifestation of JC virus infection, B. Late manifestation of AIDS, C. Cerebellar involvements is unknown, D. none
C: Cerebellar involvements is unknown
Answer: C: Cerebellar involvements is unknown 
Explanation: . *Progressive multi focal leukoencephalopathy characterised by cytological alternations in both astrocytes and oligodendrocytes . *Oligodendrocytes are enlarged ,densely staining nuclei that contain viral inclusions formed by crystallinearrays of JC virus paicles *Almost all patients will have underlying immunocompromissive disorders ,most common associated condition is AIDS(80%), hematological malignancy(13%), transplant recipient(5%) and chronic inflammatory disease(2%). Ref Harrison20th edition pg 2456