This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy, Subject name: Pharmacology
Amoxycillin is better than ampicillin due to: 
Select and explain. 
A. Better biovailability if taken with food, B. Lesser biovailability if taken with food, C. Incidence of diarrhea is higher, D. More active against Shigella and H. influenza
A: Better biovailability if taken with food
Answer: A: Better biovailability if taken with food 
Explanation: Amoxicillin It is a close congener of ampicillin (but not a prodrug); similar to it in all respects except: * Oral absorption is better; food does not interfere with absorption; higher and more sustained blood levels are produced. * Incidence of diarrhoea is lower. * It is less active against Shigella and H. influenzae. Many physicians now prefer it over ampicillin for bronchitis, urinary infections, SABE and gonorrhoea. ESSENTIALS OF MEDICAL PHARMACOLOGY K.D.TRIPATHI SIXTH EDITION PAGE NO:701