This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
Withdrawal bleeding following administration of progestogen in a case of secondary amenorrhoea indicates all except: 
Select and explain. 
A. Absence of pregnancy, B. Production of endogenous estrogen,, C. Endometrium is responsive to estrogen, D. Defect in pituitary gonadal axis
D: Defect in pituitary gonadal axis
Answer: D: Defect in pituitary gonadal axis 
Explanation: None