This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: First-Trimester Spontaneous Abortion, Subject name: Gynaecology & Obstetrics
Most common cause of spontaneous abortion in first trimester: 
Select and explain. 
A. Chromosomal anomalies, B. Uterine anomalies, C. Antiphospholipid antibody syndrome, D. Hypothyroidism
A: Chromosomal anomalies
Answer: A: Chromosomal anomalies 
Explanation: Ans: A (Chromosomal anomalies) Ref: Dutta: Textbook of Obstetrics 7th ed pg 160Explanation:COMMON CAUSES OF MISCARRIAGEFirst TrimesterGenetic factors Endocrine Immunological disorders InfectionUnexplainedSecond TrimesterAnatomicCervical incompetenceBicomuate uterusSeptate uterusUterine synechiaeUterine fibroidMaternal medical illnessUnexplained