This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Characteristic histopathology finding in Whipples disease is ? 
Select and explain. 
A. PAS positive macrophages and rod shaped bacilli in lamina propria, B. Shoened thickened villi with increased crypt depth, C. Blunting and flattening of mucosal surface and absent villi, D. Mononuclear infiltration at base of crypts
A: PAS positive macrophages and rod shaped bacilli in lamina propria
Answer: A: PAS positive macrophages and rod shaped bacilli in lamina propria 
Explanation: Ans. is 'a' i.e., PAS positive macrophages and rod shaped bacilli in lamina propriaThe hallmark of Whipple's disease is a small intestinal mucosa laden with distended macrophages in the lamina propria- the macrophages contain periodic acid-schiff (PAS) positive granules and rod shaped bacilli by electron microscopy.Three forms of Malabsorption Syndromes are often asked and the basic understanding of these is able to exclude a large number of questions.