This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.N.S, Subject name: Medicine
Migraine is due to 
Select and explain. 
A. Dilatation of cranial aeries, B. Constriction of cranial aeries, C. Coical spreading dissociation, D. Meningial inflammation
C: Coical spreading dissociation
Answer: C: Coical spreading dissociation 
Explanation: K.D Tripathy essentials of medical pharmacology 7th edition . *Neurogenic theory consider it to be spreading depression of coical electrical activity followed by vascular phenomena.