This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.N.S, Subject name: Pharmacology
Mechanism of action of amoxapine is :- 
Select and explain. 
A. SNRI, B. SSRI, C. NA + 5HT reuptake inhibitor, D. Predominantly NA reuptake inhibitor
D: Predominantly NA reuptake inhibitor
Answer: D: Predominantly NA reuptake inhibitor 
Explanation: Ans. is 'd' i.e., Predominantly NA reuptake inhibitor Antidepressants|| |Typical(Inhibits reuptake or metabolism of Na/5-HT) Atypical(Act by other mechanism)|* Trazodone* Mianserine* Mitrazapine* Venlafaxine* Duloxetine* Tianeptine* Amineptine* Bupropion|||MAO-A inhibitorTricyclic antidepressants* NA+5HT reuptake inhibitors# Imipramine# Amitriptyline# Trimipramine# Doxepin# Dothiepin# Clomipramine* Predominantly NA reuptake inhibitors# Desipramine# Nortriptyline# Amoxapine# ReboxetineSelective serotonin reuptake inhibitors (SSRI)* Fluoxetine* Paroxetine* Sertaline* Citalopram* Escitalopram* Fluvoxamine