This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Substance Related and Addictive Disorders, Subject name: Psychiatry
Which of the following drugs have no role in opioid detoxification? 
Select and explain. 
A. Naloxone, B. Methadone, C. Buprenorphine, D. Clonidine
A: Naloxone
Answer: A: Naloxone 
Explanation: Naloxone is an opioid antagonist which is used in opiod toxicity. It has no role is opioid detoxification. Opioid detoxification DOC -methadone, buprenorphine, dextropropoxyphene (long acting opioids) - Clonidine / lofexidine can also be used NALOXONE is an opioid receptor antagonist and used in case of opioid overdose; NOT in OPOID DETOXIFICATION