This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Pharmacology
Moxidectin was approved by FDA recently for 
Select and explain. 
A. Filariasis, B. Onchocerca volvulus, C. Hypeension, D. Scabies
B: Onchocerca volvulus
Answer: B: Onchocerca volvulus 
Explanation: moxidectin is a macro cyclic lactone which is similar to ivermectin.it binds to the glutamate gated chloride channels leading to increased permeability and hyperpolarization and muscle paralysis. Ref: www.fda.gov.in