This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Tumors, Subject name: Orthopaedics
Osteogenic sarcoma arise from - 
Select and explain. 
A. Epiphysis, B. Metaphysis, C. Growth plate, D. Epiphyseal coex
B: Metaphysis
Answer: B: Metaphysis 
Explanation: The tumor most commonly begins in the Metaphysis The most common site of involvement is Metaphysis of long bone around knee Lower end of femur Upper end of tibia Refer Maheshwari 4th/e p 232