This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
ATT most commonly implicated in causing peripheral neuropathy are: 
Select and explain. 
A. Rifampicin, B. Pyrazinamide, C. INH, D. Ethambutol
C: INH
Answer: C: INH 
Explanation: Peripheral neuritis and a variety of neurological manifestations (paraesthesias, numbness, mental disturbances, rarely convulsions) are the most important dose-dependent toxic effects of INH.
These are due to interference with the utilization of pyridoxine and its increased excretion in urine.