This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Which is the most common site of metastasis? 
Select and explain. 
A. Lung, B. Bone, C. Liver, D. Brain
C: Liver
Answer: C: Liver 
Explanation: o The liver is uniquely vulnerable to invasion by tumor cells.o Its size, high rate of blood flow, double perfusion by the hepatic aery and poal vein, and kupffer cell filtration function combine to make it the most common site of metastasis after the lymph node.