This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Pharmacology
Drug of choice for nephrogenic diabetes insipidus is:- 
Select and explain. 
A. Mannitol, B. Spironolactone, C. Thiazides, D. Demeclocycline
C: Thiazides
Answer: C: Thiazides 
Explanation: Diabetes insipidus Central Nephrogenic Desmopressin (DOC) Thiazides (DOC) (As endogenous ADH is already present that is not able to work, so there is no point in giving ADH(desmopressin))