This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Examine the given pedigree chart. Which one of the following diseases is the most likely for this situation ? 
Select and explain. 
A. Neurofibromatosis, B. Beta-thalassemia, C. Colour blindness, D. Vitamin D resistant rickets
B: Beta-thalassemia
Answer: B: Beta-thalassemia 
Explanation: None