This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Sympathetic System, Subject name: Pharmacology
Brinzolamide is 
Select and explain. 
A. Competitive and reversible carbonic anhydrase inhibitor, B. Non-competitive and reversible carbonic anhydrase inhibitor, C. Competitive and irreversible carbonic anhydrase inhibitor, D. Non-competitive and irreversible carbonic anhydrase inhibitor
B: Non-competitive and reversible carbonic anhydrase inhibitor
Answer: B: Non-competitive and reversible carbonic anhydrase inhibitor 
Explanation: Carbonic anhydrase (CAse) is an enzyme which catalyses the reversible reaction H2O + CO2 - H2C03 Hence, Carbonic anhydrase functions in CO2 and HC03 transpo and in H+ ion secretion. Carbonic anhydrase inhibitors act by non-competitive but reversible inhibition of the enzyme -Decreases the production of aqueous humor from ciliary body epithelium. Ex: Acetazolamide, dorzolamide and Brinzolamide.