This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Treatment of choice for salmonella typhi ? 
Select and explain. 
A. Cephalexin, B. Gentamicin, C. Co-trimoxazole, D. Ciprofloxacin
D: Ciprofloxacin
Answer: D: Ciprofloxacin 
Explanation: Ans. is `d' i.e., Ciprofloxacin Treatment of Typhoid fever o Empirical treatment ---> Ceftriaxone, Azithromycin. o Fully susceptible ---> Ciprofloxacin (First line), Amioxicil lin (second line), Chloramphenicol, Trimethoprim - Sulfamethoxazole. o Multidrug resistant ---> Ciprofloxacin, Ceptriaxone, Azithromycin. o Nalidixic acid resistant --> Ceftriaxone, Azithromycin, high dose ciprofloxacin. Note : For susceptible organism ciprofloxacin is the DOC in typhoid fever. Treatment of carrier o Amoxicillin or ciprofloxacin with or without cholecystectomy.