This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pathology
In which of the following vegetation are friable and easily detachable from the cardiac valves 
Select and explain. 
A. Rheumatic fever, B. Rheumatoid hea, C. SLE, D. Infective endocarditis
D: Infective endocarditis
Answer: D: Infective endocarditis 
Explanation: Infective endocarditis is a serious infection mandating promt diagnosis and intervention. Microbial invasion of hea valves or mural endocardium often with destruction of the underlying cardiac tissue characteristically results in bulky , friable vegetation composed of necrotic debris, thrombus, and organisms. The aoa , aneurysmal sacs , other blood vessels and prosthetic devices also can be affected. Robbins 9 th edition page no. 393