This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Beta thalasemmia, Subject name: Pathology
Ideally children with thalassemia should be transfused with: 
Select and explain. 
A. Packed RBC, B. Platelet rich plasma, C. Saline washed packed RBC, D. Whole blood
C: Saline washed packed RBC
Answer: C: Saline washed packed RBC 
Explanation: - Saline washed RBCs are specially indicated in conditions requiring repeated transfusion when the chances of uicarial reactions due to plasma is high. - These have negligible plasma proteins and just 10% leucocytes. - It is preferred in the management of babies suffering from thalassemia and paroxysmal nocturnal hemoglobinuria.