This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Ohopedics Oncology, Subject name: Orthopaedics
Most common malignancy that metastasizes to the spine in females is: 
Select and explain. 
A. Thyroid, B. Prostate, C. Lung, D. Breast
D: Breast
Answer: D: Breast 
Explanation: Metastatic Bone Disease Most common sites of primary for bone metastasis. In males - Prostate > Lung In Female - Breast > Lung In Children - Neuroblastoma Overall most common is breast Skeletal sites most frequently involved Spine (Dorsal) Lytic expansile metastasis seen in Renal cancer Thyroid carcinomas Purely Osteoblastic secondaries Prostate/Carcinoid/Medulloblastoma