This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Which of the following is NOT a characteristic of Carcinoma esophagus? 
Select and explain. 
A. Adenocarcinoma, B. Middle one third affected, C. Dysphagia, D. Pernicious anemia often present
D: Pernicious anemia often present
Answer: D: Pernicious anemia often present 
Explanation: Adenocarcinoma and squamous cell carcinoma are the two common type of carcinoma esophagus. Other rare type of esophageal carcinoma include undifferentiated, carcinoma, malignant melanoma, lymphoma and sarcoma. Middle one third is most common site of carcinoma and is involved in about 60% of esophageal cancers. Dysphagia is the most common symptom of esophageal carcinoma. It initially occur with solids food then gradually progress to semi solid and then to liquids. Pernicious anemia is a risk factor for carcinoma stomach, it is not associated with esophageal carcinoma. Ref: Harrison 17/e, Page 647 ; Sabiston 17/e, Page 1119