This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Microbiology
BCR-ABL1 gene fusion is seen in all of the following Except 
Select and explain. 
A. Acute myeloid leukemia, B. Chronic myeloid leukemia, C. Acute lymphoblastic leukemia, D. Chronic lymphocytic leukemia
D: Chronic lymphocytic leukemia
Answer: D: Chronic lymphocytic leukemia 
Explanation: Translocation between chromosome 9 and chromosome 22 leading to fusion of BCR gene with ABL1 gene is seen characteristically in chronic myeloid leukemia. However, this genetic signature is also seen in ALL where it poends a bad prognosis and in AML as per recent WHO update.