This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: miscellaneous, Subject name: Biochemistry
Home to bilirubin conversion is carried out by 
Select and explain. 
A. Heme oxygenase, B. Heme reductase, C. Heme isomerase, D. Heme hydrolase
A: Heme oxygenase
Answer: A: Heme oxygenase 
Explanation: Within the macrophage, heme derived from haemoglobin is broken down by heme oxygenase, conveing it to biliverdin Carbon monoxide and iron arereleased as by-productsReference: Harper biochemistry 30th edition page no 672