This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Disorder of Metabolism & Connective Tissue, Subject name: Medicine
This patient with diffuse, nonencapsulated fatty deposits is most likely to have a history of which one of the following? 
Select and explain. 
A. Alcohol dependency, B. Hypercalcemia, C. Renal insufficiency, D. Rheumatoid arthritis
A: Alcohol dependency
Answer: A: Alcohol dependency 
Explanation: Answer A. Alcohol dependencyMadelung's disease (also known as benign symmetric lipomatosis) is a rare disorder of unknown cause and was the diagnosis in this case. Up to 90% of patients have a history of chronic alcoholism, and there is a strong male predominance.