This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
The bacterial drug resistance in tuberculosis results from : 
Select and explain. 
A. Transduction, B. Transformation, C. Plasmid mediated, D. Mutation
D: Mutation
Answer: D: Mutation 
Explanation: Resistance to INH occurs due to point mutation in inhA or katG genes.
Resistance to rifampicin occurs due to point mutation in rpoB genes.
Resistance to ethambutol is due to mutations resulting in overexpression of the embB gene.