This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Complications Of Anaesthesia, Subject name: Anaesthesia
CNS affection of a local anesthetic agent leads to? 
Select and explain. 
A. Convulsion, B. Perioral numbness, C. Depression, D. All of the above
D: All of the above
Answer: D: All of the above 
Explanation: Ans is 'd' i.e. All of the above Manifestations of local anesthetic toxicityA. Early symptoms (Prodrome)Circumoral numbness, dizziness, tongue paresthesia, restlesness, tinnitus, agitation.B. CNS symptoms These are biphasic i.e. excitation (convulsions, restlessness, agitation 8c tinnitus), followed by depression (drowsiness, disorientation, respiratory depression, unconciousness).C. Cardiovascular manifestationshypotension, cardiac arrest, coma