This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hemoglobinopathies: Sickle cell anemia, Subject name: Pathology
Schistocytes in peripheral smear is seen in all except: 
Select and explain. 
A. DIC, B. Sickle cell anemia, C. TTP, D. HUS
B: Sickle cell anemia
Answer: B: Sickle cell anemia 
Explanation: Irregular fragmented red cells appearing as helmet shaped or triangular. Schistocytes are seen in all conditions having Micro or Macro angiopathic hemolytic anemia. Macroangiopathic Hemolytic anemia - Prosthetic cardiac valve transplantation. Sickle cell disease is inherited disease associated with sickled RBCs