This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immune system, Subject name: Medicine
Most common carcinoma associated with RA 
Select and explain. 
A. Diffuse large B cell lymphoma, B. Large granular lymphocytic leukemia, C. Chronic lymphocytic leukemia, D. None
A: Diffuse large B cell lymphoma
Answer: A: Diffuse large B cell lymphoma 
Explanation: Large coho studies have shown a two- to fourfold increased risk of lymphoma in RA patients compared with the general population. The most common histopathologic type of lymphoma is a diffuse large B cell lymphoma. The risk of developing lymphoma increases if the patient has high levels of disease activity or Felty's syndrome. Ref Harrispns 20e p2530