This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolic disorders, Subject name: Pediatrics
Only male are affected in 
Select and explain. 
A. Scheie's syndrome, B. Hunter's syndrome, C. Hurler's syndrome, D. Gaucher's disease
B: Hunter's syndrome
Answer: B: Hunter's syndrome 
Explanation: Hunter's syndrome belongs to Type II mucopolysaccharidoses in which mucopolysaccharides accumulate in the lysosomes causing disorganization of the cell structure & function.This syndrome is characterised by mild mental retardation;marked skeletal changes like thickening of the skull,marked deformity of sella tursica,broad spatula like ribs,beak shaped veebrae(around L1 veebra) and proximal tapering of metacarpals-these abnormalities are referred to as dysostosis multiplex;coarse facies & hepatosplenomegaly. Reference:Essential pediatrics-Ghai,8th edition,page no: 660,661.