This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Pharmacology
Paradoxical action among diuretics is seen with 
Select and explain. 
A. Thiazide, B. Triamterene, C. Spirinolactone, D. Furosemide
A: Thiazide
Answer: A: Thiazide 
Explanation: DIURETICS ARE CONTRAINDICATED IN DIABETES IN WHICH THERE IS AN INCREASED EXCRETION OF URINE But, Thiazides are used in diabetes insipidus- paradoxical action -they create mild hypovolemia which encourages salt and water uptake in the proximal tubule and thus improve nephrogenic diabetes insipidus- action may be mediated through CAMP- poorly understood REF KD Tripathi 8th ed