This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Autonomic nervous system, Subject name: Pharmacology
Which of the following is a most reliable clinical endpoint to indicate adequate atropinization in organophosphorus poisoning 
Select and explain. 
A. Pupillary dilation, B. Control of diarrhoea, C. Hea rate more than or equal to 100 beats per minute, D. Absence of Pulmonary secretion
D: Absence of Pulmonary secretion
Answer: D: Absence of Pulmonary secretion 
Explanation: Refer emedicine.medscape.com signs of atropinization appears. Thesesigns include warm, dry, flushed skin; dilated pupils; and an increased hea rate. Atropine should be used for at least 24 hours to reverse the cholinergic signs while the organophosphate is metabolized Atropine - The endpoint for atropine is dried pulmonary secretions and adequate oxygenation. Tachycardia and mydriasis must not be used to limit or to stop subsequent doses of atropine. The main concern with OP toxicity is respiratory failure from excessive airway secretions