This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Neoplasia, Subject name: Pathology
Mucosal melanosis and hamartomatous polyps are seen in? 
Select and explain. 
A. Peutz-Jeghers syndrome, B. Cronkhite Canada syndrome, C. Familial adenomatous polyposis, D. Hereditary non polyposis colonic cancer
A: Peutz-Jeghers syndrome
Answer: A: Peutz-Jeghers syndrome 
Explanation: Ref: Harrison 19th ed., P 240* Peutz-Jeghers syndrome is characterized by dark brown spots on lips, buccal mucosa, nose and around eyes. There is concomitant intestinal polyposis. The most common location of polyps is in jejunum.* It is an autosomal dominant disorder with STK11 mutation.* The malignant potential of polyps ranges from never to rare transformation.