This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Vitamins and Minerals, Subject name: Biochemistry
Biotin deficiency is due to 
Select and explain. 
A. Avidin, B. Flavoproteins, C. Metallo flavoproteins, D. Oxireductase
A: Avidin
Answer: A: Avidin 
Explanation: (Avidine) (146 - U.S 3rd) (178- R.S. 7th)Biotin deficiency (anti egg, white injury factor, vitamin B7 or vitamin - H) is a sulfur containing B complex. It is directly participates as coenzyme in the carboxylation reactions* High consumption of raw egg. The raw egg white contains a glycoprotein - avidin. Which is highly binds with biotin and blocks its absorption from the intestine.