This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous (Pharmacology), Subject name: Pharmacology
A 40 year old woman was on chemotherapy for 6 months for Ovarian carcinoma. Now she presented with a progressive bilateral Sensorineural hearing loss. The Drug responsible for this includes 
Select and explain. 
A. Cisplatin, B. Doxorubicin, C. Cyclophosphamide, D. Paclitaxel
A: Cisplatin
Answer: A: Cisplatin 
Explanation: (A) Cisplatin# Platinum-containing chemotherapeutic agents, including cisplatin and carboplatin, are associated with cochleotoxicity characterized by high-frequency hearing loss and tinnitus.> Ototoxicity is less frequently seen with the related compound oxaliplatin.