This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
All are true about Gilbert's Syndrome Except - 
Select and explain. 
A. Mild conjugated hyper bilirubinemia, B. Autosomal dominant, C. Normal liver histology, D. Almost normal liver function
A: Mild conjugated hyper bilirubinemia
Answer: A: Mild conjugated hyper bilirubinemia 
Explanation: Ans-AGilbert syndrome causes unconjugated hyperbilirubinemia.Gilbert's syndrome is an autosomal dominant disorder*.Characteristic features are :*Mild unconjugated hyperbilirubinemia due to:Decreased hepatic uptake of bilirubinDecreased activity of uridyl glucuronyl transferase (causing defective conjugation).*Standard hepatic biochemical tests are normal.*Normal hepatic histology.Gilbert's syndrome is a type of congenital hyperbilirubinemia.Other types of congenital hyperbilirubinemia.*Crigler Najjar* Type I-The complete absence of the enzyme - UDP glucuronyl transferase.Causes severe jaundice, death in early life.Unconjugated hyperbilirubinemia* Type II-* Partial absence of enzyme.Dubin-Johnson-a defect in excretion of conjugated bilirubin, therefore, causes conjugated hyperbilirubinemia.*Rotor's syndrome Same as Dubin-Johnson. Note :The difference between Dubin-Johnson and Rotor's Syndrome.In Dubin-Johnson there is an accumulation of pigment in the hepatocytes, imparting a brown or black color to the liver.Mnemonic - (Michael) Johnson is black