This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General anaesthesia, Subject name: Anaesthesia
Anaesthetic gas with maximum respiratory irritation 
Select and explain. 
A. Desflurane, B. Sevoflurane, C. Enflurane, D. Halothane
A: Desflurane
Answer: A: Desflurane 
Explanation: * Desflurane, unlike halothane or sevoflurane has a pungent smell which makes it unpleasant for inhalational induction. * When more than 6% desflurane is used, the pungency produces salivation, airway irritation, breath holding and coughing. Ref:- Stoelting's Pharmacology and Physiology in Anesthetic Practice 5th edition; pg num:- 101