This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
The main aim of an adjuvant is to increase? 
Select and explain. 
A. Distribution, B. Absorption, C. Antigenicity, D. Metabolism
C: Antigenicity
Answer: C: Antigenicity 
Explanation: Ans. is 'c' i.e., Antigenicity Adjuvants . Any substance that enhances the immunogenicity of an antigen. . Actions : - May confer immunogenicity on nonantigenic substances. - Increases the concentration and presistence of the circulating antibodies. - Enhances the degree of cellular immunity - Leads to production of adjuvant disease such as allergic disseminated encephalomyelitis. . The most potent adjuvant is Freund's complete adjuvant which is the incomplete adjuvant along with a suspension of killed tubercle bacilli. . Other adjuvants. - Incorporation of protein antigen in the water phase of water in oil emulsion (Freund's incomplete adjuvant) - Aluminium hydroxide and Aluminium phosphate are commonly used with human vaccines. - Gram negative bacilli show an adjuvant effect due to their lipopolysaccharide (endotoxin) fraction. - Bordetella peussis acts as a good adjuvant for diphtheria and tetanus toxoid in triple vaccine.