This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.V.S., Subject name: Pediatrics
All of the following are associated with good prognosis in childhood leukemia except: 
Select and explain. 
A. Hyperdiploidy, B. Female sex, C. Precursor B-cell ALL, D. t(12; 21) translocation
C: Precursor B-cell ALL
Answer: C: Precursor B-cell ALL 
Explanation: c. Precursor B-cell ALL(Ref: Nelson's 20/e p 2437, Ghai 8/e p 599)Precursor B-cell ALL, B-cell ALL and T-cell ALL has poor prognosis.