This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Adverse Drug Effect, Subject name: Pharmacology
Drug causing Reye syndrome: 
Select and explain. 
A. Celecoxib, B. Aspirin, C. Diclofenac, D. Paracetamol
B: Aspirin
Answer: B: Aspirin 
Explanation: Ans. B. AspirinAspirin is non-selective irreversible COX inhibitor.it has antipyretic, analgesic and anti-inflammatory properties. Aspirin is known to cause salicylism in adults. It is contraindicated in children who are less than 12 years as they are at increased risk of Reye syndrome which include diarrhea, vomiting, seizure and loss of consciousness.