This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Gastrointestinal tract, Subject name: Pediatrics
Conjugated bilirubin is increased in ? 
Select and explain. 
A. Rotor syndrome, B. Gilbe's syndrome, C. Crigler Najjar syndrome 1, D. Crigler Najjar syndrome 2
A: Rotor syndrome
Answer: A: Rotor syndrome 
Explanation: crigler najjar syndrome-1:defect in conjugation,so unconjugated bilirubin level increases to more than 20mg/dl crigler najjar syndrome-ll:second stage of conjugation is defective Gilbe&;ssyndrome:defect in the uptake of bilirubin by liver. Rotor&;s syndrome:bilirubin excretion is defective, but there is no staining of liver. TEXTBOOK OF BIOCHEMISTRY,D.M.VASUDEVAN,PG NO:251,252,6th edition