This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: recent papers  obst, Subject name: Gynaecology & Obstetrics
MgSO4 have no role in prevention of 
Select and explain. 
A. Seizures in severe pre-eclampsia, B. RDS in premature baby, C. Recurrent seizures in eclampsia, D. Neuroprotection
B: RDS in premature baby
Answer: B: RDS in premature baby 
Explanation: Magnesium sulphate: - Mechanism of action:- * Reduced presynaptic release of the neurotransmitter glutamate * Blockade of glutaminergic n-methyl-d-aspaate (nmda) receptor * Potentiation of adenosine action * Improved calcium buffering by mitochondria * Blockage of calcium entry voltage-gated channels Used for: - * Severe preeclampsia * Recurrent eclamptic seizures * Neuroprotection Must check: - * Urine output * Respiratory rate * Patellar reflexes Ref:- Williams obstetrics 25th Edition; Pg num:- 38/68