This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Gonads, Subject name: Pediatrics
Hypergonadotropic hypogonadism in seen in all except- 
Select and explain. 
A. Down, B. Turner, C. Swyer's syndrome, D. Klinefelter syndrome
A: Down
Answer: A: Down 
Explanation: Ans. is 'a' i.e., DownHypergonadotropic hypogonadismo Also K/a primary or peripheral hypogonadism.o Characterised by hypogonadism due to an impaired response of the gonads to the gonadotropin, FSH and LH.o In turn a lack of sex steroid production and elevated gonadotropin level.Causes: Chromosomal abnormalitieso Turner's symdromeo Klinefelter syndromeo Swyer's syndromeEnzyme defecto 17 a, hydroxylaseo 17,20 lyase deficiency