This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Which of the following statement is true regarding inverse agonists? 
Select and explain. 
A. Binds to receptor and causes intended action, B. Binds to receptor and causes opposite action, C. Binds to receptor and causes no action, D. Binds to receptor and causes submaximal action
B: Binds to receptor and causes opposite action
Answer: B: Binds to receptor and causes opposite action 
Explanation: Inverse agonist activates a receptor to produce an effect in the opposite direction to that of an agonist. It has high affinity for the receptor, but intrinsic activity with a minus sign. Ref: Essentials of Medical Pharmacology By KD Tripathi, 5th Edition, Pages 35, 37