This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Diffuse peritonitis following appendicitis is usually seen - 
Select and explain. 
A. When appendicular perforation occurs early (within 24 hours), B. When perforation occurs late (after 24 hours), C. Particularly in non-obstructive appendicitis, D. When antibiotics are withheld
A: When appendicular perforation occurs early (within 24 hours)
Answer: A: When appendicular perforation occurs early (within 24 hours) 
Explanation: In late stages greater omentum and small bowel become adherent to inflamed appendix, walling off the spread of peritoneal contamination