This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetic and genetic disorders, Subject name: Pediatrics
A 4 year baby is having large face, large jaw, large ear and macro orchidism is 
Select and explain. 
A. Mc Cuneal bright syndrome, B. Down's syndrome, C. Cri-du chat syndrome, D. Fragile X syndrome
D: Fragile X syndrome
Answer: D: Fragile X syndrome 
Explanation: A child with large face large ears large jaw and macro orchidism has fragile X syndrome It is due to a fragile site in one of the distal long arm of chromosome Xq27.3 Reference: Nelson TB of pediatrics pg 411 edition 19.