This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nephrotic Syndrome, Subject name: Pathology
Finnish type of nephrotic syndrome is associated with mutations of which of the following? 
Select and explain. 
A. Nephrin, B. Podocin, C. Alpha actinin, D. CD2 activated protein
A: Nephrin
Answer: A: Nephrin 
Explanation: NPHS1 gene mutations = Congenital nephrotic syndrome of the Finnish type, producing a minimal-change disease like glomerulopathy with extensive foot process effacement. NPHS1 is located on chromosome 19q13 and encodes the protein nephrin.