This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
All of the following are true regarding hemolytic anemia except: March 2008 and 2011, March 2013 
Select and explain. 
A. Raised haptoglobin levels, B. Raised unconjugated bilirubin, C. Reticulocytosis, D. Hemosiderinuria indicates intravascular hemolysis
A: Raised haptoglobin levels
Answer: A: Raised haptoglobin levels 
Explanation: Ans. A: Raised haptoglobin levelsIn hemolytic anemia, the level of unconjugated bilirubin in the blood is elevated. This may lead to jaundice. The level of lactate dehydrogenase (LDH) in the blood is elevatedHaptoglobin levels are decreasedIf the direct Coombs test is positive, hemolysis is caused by an immune process.Hemosiderin in the urine indicates chronic intravascular hemolysis.There is also urobilinogen in the urine. Peripheral blood smear microscopy:Fragments of the red blood cells ("schistocytes") can be presentSome red blood cells may appear smaller and rounder than usual (spherocytes)Reticulocytes are present in elevated numbers.