This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti Microbial, Subject name: Pharmacology
Which group of drugs potentiates the action of Neuromuscular blockers? 
Select and explain. 
A. Aminoglycosides, B. Cephalosporins, C. Ampicillin, D. Penicillin
A: Aminoglycosides
Answer: A: Aminoglycosides 
Explanation: Ref: Goodman & Gillman, The pharmacological basis of therapeutics. I2'h edition, Pg No. 1514Explanation:None of the other drugs mentioned have any effect on ACh neurotransmission.Potentiating neuromuscular blockers is a class effect exhibited by all aminoglycoside antibiotics.This is highest with neomycin followed by Kanamycin Amikacin, gentamicin and TobramycinMore common with intrapleural and intraperitoneal instillation of large doses of one of these agents.Can also seen with intravenous and intramuscular routeThis is due to the fact that they inhibit the release of prejunctional release of ACh as well as reducing the postsynaptic sensitivity to neurotransmitter.Hence aminoglycosides should be used with caution in myasthenia gravis patients