This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
High hepatic first-pass metabolism is seen in all EXCEPT 
Select and explain. 
A. Insulin, B. Propranolol, C. Lignocaine, D. Nitroglycerin
A: Insulin
Answer: A: Insulin 
Explanation: - Except for Insulin, all the three options undergo high first pass metabolism.
- Drugs showing high first pass metabolism

   Isoprenaline
   Lidocaine
   Hydrocortisone
   Testosterone
   Propranolol
   Verapamil
   Salbutamol
   Morphine
   Pethidine