This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy: General Principles, Subject name: Pharmacology
Which of the following parameters is not monitored in a patient on methotrexate therapy? 
Select and explain. 
A. Liver function tests, B. Lung function test, C. Eye examination, D. Hemogramz
C: Eye examination
Answer: C: Eye examination 
Explanation: Ans. (C) Eye examination(Ref: CMDT 2010, 1501)Methotrexate toxicities include:MyelosuppressionNephrotoxicityHepatotoxicityNeurotoxicity (with intrathecal administration and high-dose therapy)PhotosensitivityPulmonary toxicityMultiple drug interactions which may enhance toxicities (avoid aspirin, penicillins, NSAIDs, omeprazole, TMP-SMZ)