This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Psychiatry
Neuritic plaques are associated with which of the following disease? 
Select and explain. 
A. Alzheimer's disease, B. Multiple sclerosis, C. Stroke, D. None of the above
A: Alzheimer's disease
Answer: A: Alzheimer's disease 
Explanation: Neuritic plaques are associated with Alzheimer's disease. Neuritic plaques range in size from 20 to 200 mm in diameter; microglial cells and reactive astrocytes are present at their periphery. Plaques are found in the hippocampus, amygdala, and neocoex, although there is usually relative sparing of primary motor and sensory coices (this also applies to neurofibrillary tangles). The amyloid core, which can be stained by Congo Red, contains several abnormal proteins. The dominant component of the amyloid plaque core is Ab, a peptide derived through specific processing events from a larger molecule, amyloid precursor protein (APP). Ref: Robbins 8th edition Chapter 28.