This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Systemic Lupus Erythematous, Subject name: Medicine
Which of the following auto antibodies is most likely to be present in a patient with systemic lupus erythematosus? 
Select and explain. 
A. Anti- ds DNA, B. Anti-RNP, C. Anti-Ro, D. Antiphospholipid
A: Anti- ds DNA
Answer: A: Anti- ds DNA 
Explanation: Subtypes of anti nuclear antibodies include anti-Smith and anti-double stranded DNA (dsDNA) antibodies (which are linked to SLE).