This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
The major source of NADPH for fatty acidsynthesis ? 
Select and explain. 
A. PPP, B. TCA cycle, C. Glycolysis, D. Glycogenolysis
A: PPP
Answer: A: PPP 
Explanation: Ans. is 'a' i.e., PPP Source of NADPH for lipogenesis NADPH is involved as donor of reducing equivalentse in both the reduction of 3-ketoacyl by 3 ketoacyl reductase and of 2,3- unsasturated acyl by enoyl reductase. The main source of NADPH for lipogenesis is the pentose phosphate pathway: PPP (Hexose monophosphate shunt: HMP shunt)deg. Other sources of NADPH include:- The reaction that conves malate to pyruvate catalyzed by malic enzyme. Exramitrochondrial isocitrate dehydrogenase.