This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: JIPMER 2017, Subject name: Pharmacology
The risk of carbamazepine induced Stevens-Johnson syndrome is increased in the presence of which of the following genes? 
Select and explain. 
A. HLA-B* 5801, B. HLA-B* 1502, C. HLA-B* 5701, D. HLA-B 27
B: HLA-B* 1502
Answer: B: HLA-B* 1502 
Explanation: HLA DRUG DISEASE B1502 CARBAMAZEPINE STEVEN JOHNSON SYNDROME B5801 ALLOPURINOL SKIN REACTION B5701 ABACAVIR MI B53 MALARIA PROTECTION B27 ANKYLOSING SPONDYLITIS