This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Medicine
Commonest presentation of sickle cell anaemia is 
Select and explain. 
A. Priapism, B. Bone pain, C. Fever, D. Splenomegaly
B: Bone pain
Answer: B: Bone pain 
Explanation: Sickle cell anemis causes Vaso-occlusive crisis : This means plugging of small vessels in the bone produces severe bone pain. This affects areas of active marrow: the hands and feets in children(dactylitis) or femora, humeri, ribs, pelvis and veebrae in adults. Reference : Davidson, 23rd Edition, page no : 952.