This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Phospho-dephosphorylation of phosphofructokinase and fructose 1, 6, biphosphatase by fructose 2, 6,biphosphate regulation is seen in 
Select and explain. 
A. Brain, B. Liver, C. Adrenal cortex, D. RBC
B: Liver
Answer: B: Liver 
Explanation: Fructose 2, 6-biphosphate has unique role in regulation of glycolysis and gluconeogenesis in liver.