This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hepatitis, Subject name: Pathology
Autoimmune hepatitis type I is characterized by presence of all of the following except: 
Select and explain. 
A. ANA, B. SMA, C. Anti-LKM-1, D. none of these
C: Anti-LKM-1
Answer: C: Anti-LKM-1 
Explanation: Autoimmune hepatitisis a chronic, progressive hepatitis. Type 1: Type 2: Middle-aged to older individuals Antinuclear (ANA), Anti-smooth muscle actin (SMA). Children and teenagers Anti-liver kidney microsome-1 (anti-LKM-1) antibodies, directed against CYP2D6, and anti liver cytosol-1 (ACL-1) antibodies.