This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Busulfan toxicity does not include - 
Select and explain. 
A. Hyperpigmentation, B. Toxic carditis, C. Hyperuricemia, D. Pulmonary fibrosis
B: Toxic carditis
Answer: B: Toxic carditis 
Explanation: Ans. is 'b' i.e., Toxic carditis o Adverse effects of busulfan --> Myelosuppression, hyperuricemia, pulmonary fibrosis, sterility, impotence, amenorrhea, addison's disease like syndrome (asthenia and hypotension). o High dose causes veno-occlusive disease of liver, seizures, hemorrhagic cystitis, alopecia, cataract. About option 'a' - In addison's disease there is hyperpigmentation (Busulfan causes addison's disease like syndrome).