This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
All of the following statements regarding streptokinase are true Except 
Select and explain. 
A. It is a protein produced by streptococci, B. Its complex with plasminogen is inhibited by alpha 2 antiplasmin, C. It may rarely produce anaphylaxis, D. It is initially given as a loading dose
B: Its complex with plasminogen is inhibited by alpha 2 antiplasmin
Answer: B: Its complex with plasminogen is inhibited by alpha 2 antiplasmin 
Explanation: Streptokinase is a 47-kDa protein produced by beta-hemolytic streptococci. It forms a stable complex with plasminogen, which is not inhibited by antiplasmin. A large loading dose is given intravenously to overcome antibodies that may be formed from prior streptococcal infections. Being a foreign protein it may rarely cause anaphylaxis.