This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Substance abuse, Subject name: Psychiatry
1st line treatment for smoking cessation includes 
Select and explain. 
A. Noriptyline, B. Clonidine, C. Varenicline, D. Buspirone
C: Varenicline
Answer: C: Varenicline 
Explanation: Varenicline -ALPA 4 BETA 2 paial agonist for nicotinic receptors is the new 1st line treatment for smoking dependence. Ref: Essentials of postgraduate psychiatry By JN Vyas 1st ed Pg 351