This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metastatic Bone Disease, Subject name: Orthopaedics
The following carcinoma metastasis to bone is seen in all EXCEPT: 
Select and explain. 
A. Liver, B. Thyroid, C. Prostate, D. Breast
A: Liver
Answer: A: Liver 
Explanation: (Liver): Ref: 193-AMETASTATIC BONE DISEASE* The skeleton is one of the commonest site of secondary cancer: in patients over 50years bone metastasis are seen more frequently than all primary malignant bone tumours* The commonest sites for bone metastasis are the vertebrae, pelvis, the proximal half of the femur and the humerus* Spread is usually via the blood stream: occasionally visceral tumours spread directly to adjacent bones (eg. Pelvis or ribs)* The commonest source is carcinoma of the breast; the next is frequency are carcinoma of the prostate kidney, lung, thyroid, bladder and GIT.