This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Systemic Pathology, Subject name: Pathology
A 45-year-old female underwent hysterectomy for dysfunctional uterine bleeding. Following are the gross and histological findings. Which of the following is the most likely diagnosis? 
Select and explain. 
A. Leiomyosarcoma, B. Leiomyoma, C. Mixed Mullerian tumor, D. Vaginal carcinoma
B: Leiomyoma
Answer: B: Leiomyoma 
Explanation: Diagnosis- Leiomyoma of uterus Well circumscribed growth arising in uterine wall from myometrium Can be Multiple in number hanges which can be seen- hyaline degeneration, calcification. Common signs and symptoms include abnormal bleeding, urinary frequency due to compression of the bladder, sudden pain from infarction of a large or pedunculated tumor, and impaired feility. Mutations in the gene MED12 occur in roughly 70% of uterine leiomyomas. Microscopic Examination: Well differentiated spindle shaped smooth muscle cells in a whorl pattern. Individual muscle cells are uniform in size and shape and have a characteristic oval nucleus and long, slender bipolar cytoplasmic processes. Mitotic figures are scarce.