This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Which of the following apoproteins activate esterification of cholesterol? 
Select and explain. 
A. Apo E, B. Apo C, C. Apo A1, D. Apo B100
C: Apo A1
Answer: C: Apo A1 
Explanation: Apo A1, the major apoprotein in HDL activates LCAT(Lecithin cholesterol acyltransferase).The discoid HDL whoich has mainly ApoA1 receives cholesterol from the peripheral tissues which is estrified by LCAT.Esterification makes the cholesterol hydrophobic and is pushed to the core of HDL.As more and more cholesterol is taken up and esterified,the HDL becomes spherical. Ref: Bersot T.P. (2011). Chapter 31. Drug Therapy for Hypercholesterolemia and Dyslipidemia. In B.C. Knollmann (Ed), Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e.