This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
The clinical sign of hyaline membrane disease generally first appears – 
Select and explain. 
A. In the first 6 hours of life, B. Between 12 and 24 hours of life, C. Between 36 and 48 hours of life, D. After 48 hours of lilfe
A: In the first 6 hours of life
Answer: A: In the first 6 hours of life 
Explanation: Clinical features of HMD 

Respiratory distress occurs within the first 6 hours of life.
Clinical features include -


Tachypnea                                                           
o Decreased air entry          a BP may fall

a Retraction                                 
o Fatigue                                                              
o Oliguria                  If untreated

Grunting                                                               

o Pollor 
o Ileus

Cyanosis              
Mixed respiratory & metabolic acidosis