This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Thiamine acts as a cofactor in : 
Select and explain. 
A. Conversion of pyruvate to acetyl-CoA, B. Transa mina tion reactions, C. Oxidation in respiratory chain, D. Conversion of pyridoxal to pyridoxal phosphate
A: Conversion of pyruvate to acetyl-CoA
Answer: A: Conversion of pyruvate to acetyl-CoA 
Explanation: A i.e. Conversion of Pyruvate to acetyl COA