This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
The commonest side effect of cisplatinum in a patient using it for esophageal carcinoma is : 
Select and explain. 
A. Acute tubular necrosis, B. Thrombocytopenia, C. Hepatic failure, D. Cardiomyopathy
A: Acute tubular necrosis
Answer: A: Acute tubular necrosis 
Explanation: Answer is A (Acute tubular necrosis) The most impoant toxity of cisplatinum is renal impairment - KDT 7th/777 Acute tubular necrosis is a manifestation of renal impairment and hence the answer.