This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Heberden's Ahropathy affects: 
Select and explain. 
A. Lumbar spine, B. Symmetrically large joints, C. Sacroiliac joints, D. Distal interphalangeal joints
D: Distal interphalangeal joints
Answer: D: Distal interphalangeal joints 
Explanation: Heberden's node is a disfigurement of the interphalangeal joints as a result of severe osteoahritis. Ref:Harrison's Principles of Internal Medicine, 16th Edition, Pages 2037, 2040