This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Inborn Errors of Metabolism, Subject name: Pediatrics
Hunter's syndrome is due to deficiency of: 
Select and explain. 
A. Iduronate sulfatase, B. Hexosaminidase, C. Glucocerebrosidase, D. L-Iduronidase
A: Iduronate sulfatase
Answer: A: Iduronate sulfatase 
Explanation: a. Iduronate sulfatase(Ref: Nelson's 20/e p 708-712, Ghai 8/e p 659-664)TypeNameEnzyme deficientClinical featuresIIHunter's syndromeIduronate sulfate sulfataseQCoarse face + Corneal Clouding + Dysostosis multiplex + Intellectual disability + Hepatosplenomegaly