This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Inhalational Anesthetic Agents, Subject name: Anaesthesia
Volatile agent which causes most renal toxicity is 
Select and explain. 
A. Ether, B. Isoflurane, C. Methoxyflurane, D. Sevoflurane
C: Methoxyflurane
Answer: C: Methoxyflurane 
Explanation: Methoxyflurane is most metabolized and produces more than 80 micromol/litre of flouride in blood. The amount of fluoride ions produced: Methoxyflurane: 50uM Sevoflurane: 20-30 uM Enflurane: 20uM Isoflurane and desflurane: 5uM