This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Respiratory system, Subject name: Physiology
Haldane effect 
Select and explain. 
A. Effect of 2,3 -BPG, B. Dissociation of CO2 on oxygenation, C. Dissociation of O2 on addition of CO2, D. Chloride shift
B: Dissociation of CO2 on oxygenation
Answer: B: Dissociation of CO2 on oxygenation 
Explanation: Because deoxyhemoglobin binds more H+ than oxyhemoglobin does and forms carbamino compounds more readily, binding of O2 to hemoglobin reduces its affinity for CO2 (Haldane effect).Ref: Ganong review of medical physiology 23rd edition Page no: 612