This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology and breast, Subject name: Surgery
Hashimoto's thyroiditis - True are A/E 
Select and explain. 
A. Follicular destruction, B. increase in lymphocytes, C. Oncocytic metaplasia, D. Orphan Annie eye nuclei
D: Orphan Annie eye nuclei
Answer: D: Orphan Annie eye nuclei 
Explanation: . Papillary thyroid cancer gets its name from the papillae among its cells, visible on microscopy. Features include: Characteristic Orphan Annie eye nuclear inclusions (nuclei with uniform staining, which appear empty) and psammoma bodies on light microscopy. The former is useful in identifying the follicular variant of papillary thyroid carcinomas