This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Ophthalmology
Which treatment in the optic neuritis treatment trial (ONTT) had the highest rate of recurrence 
Select and explain. 
A. IV methy prednisolone alone, B. Oral prednisone alone, C. IV methyl prednisolone and oral prednisone, D. Observation
B: Oral prednisone alone
Answer: B: Oral prednisone alone 
Explanation: Oral prednisone alone has high recurrence rate.