This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cervical Carcinoma, Subject name: Gynaecology & Obstetrics
A patient is diagnosed to have CIN II. She approaches you for advice. You can definitely tell her the risk of malignancy as 
Select and explain. 
A. 15%, B. 60%, C. 30%, D. 5%
D: 5%
Answer: D: 5% 
Explanation: CIN I and CIN II, the lesions have a 5-10% chance to progress to a high grade lesion CIN III progressing to cervical cancer is almost 10-30% Transformation Rates Form low grade CIN to High grade CIN takes around 5-6 years From High Grade CIN to invasive cancer takes around 10 years time. HPV related cervical lesions occur more on the cervical anterior lip than the lower lip (2:1 incidence).