This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
Which of the following is anti-inflammatory? 
Select and explain. 
A. IL-1, B. IL-4, C. IL-6, D. TNF-Alpha
B: IL-4
Answer: B: IL-4 
Explanation: The following are the anti-inflammatory cytokines: IL-10 TGF-b IL-4 IL-13 Pro-inflammatory cytokines IL-1 IL-6 TNF-Alpha Major anti-inflammatory cytokines include interleukin (IL)-1 receptor antagonist, IL-4, IL-6, IL-10, IL-11, and IL-13. Specific cytokine receptors for IL-1, tumor necrosis factor-alpha, and IL-18 also function as proinflammatory cytokine inhibitors ref basic pathology robbins 9th ed page 48