This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti-Fungal Drugs, Subject name: Pharmacology
Which Anti-Fungal is safe in both Renal Failure and Hepatic Failure patients ? 
Select and explain. 
A. Amphotericin B, B. Caspofungin, C. Micafungin, D. Anidulafungin
D: Anidulafungin
Answer: D: Anidulafungin 
Explanation: ECHINOCANDINS: MOA: Inhibits 1,3-b-d-glucan synthesis. Three Echinocandins are approved for clinical use: Caspofungin, Anidulafungin,and Micafungin. Used against Candida and Aspergillus sp. Fungicidal activity against Candida species while Fungistatic against Aspergillus species. CAspofungin: Candida and Aspergillus sp. Micafungin Anidulafungin: It is not metabolized by liver instead it is cleared by slow chemical degradation from the body, hence safe in both renal and hepatic failure patients.