This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous (Local and Regional Anesthesia), Subject name: Anaesthesia
EMLA constituent is - 
Select and explain. 
A. Lidocaine + Cocaine, B. Lidocaine + Prilocaine, C. Lidocaine + Bupivacaine, D. Bupivacaine + Prilocaine
B: Lidocaine + Prilocaine
Answer: B: Lidocaine + Prilocaine 
Explanation: Ans. is 'b' i.e., Lidocaine + Prilocaine Eutectic mixture of local Anaestheticso This is unique topical preparation which can anaesthetise intact skin.o It is a mixture of 2.5% lidocaine and 2.5 prilocaine.o It acts slowly and the cream must held in contact with skin for at least l hour.o EMLA is used : to make venepuncture painless especially in children, and for procedure like skin grafting & circumcision.o As systemic absorption of prilocaine can cause methemoglobinemia, EMLA should not be used on mucocutaneous membrane or in very small child.