This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
The antibody which is associated with decreased risk for nephritis in SLE is: 
Select and explain. 
A. Anti-RNP, B. Anti-Sm, C. Anti-Ro, D. Antihistone
C: Anti-Ro
Answer: C: Anti-Ro 
Explanation: Anti-Ro, and anti La antibodies are associated with low risk for nephritis in SLE.Anti-RNP is not specific for SLE, its high titres are associated with overlap syndromes.Antihistone antibodies are associated with drug induced SLE.Anti-Sm is specific for SLE but it has no definite clinical correlations.Anti-dsDNA Antibodies are highly specific for SLE and it may correlate with disease activity, nephritis, vasculitis.Ref: Harrisons principles of internal medicine, 18th edition, Page: 2726.