This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy, Subject name: Pharmacology
Drug of choice for cerebral malaria due to Pl.falciparum is 
Select and explain. 
A. Choloroquine, B. Quinine, C. Mefloquine, D. Sulfadoxine+pyrimethamine
B: Quinine
Answer: B: Quinine 
Explanation: Resistance has been developed for chloroquine for P. falciparum due to mutations in chloroquine transpoer gene, Quinine is the mainstay of treatment for cerebral and other forms of complicated malaria, through some resistance is repoed, in such cases aemisnin compounds are used. Quinine 20mg/kd loading dosein 5%dextrose infusion over 4 hrsRef: HL Sharma 3rd ed Pg:830