This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nephrotic and Nephritic syndrome, Subject name: Medicine
Leprosy causes? 
Select and explain. 
A. Rapidly progressive GN, B. Focal glomerulosclerosis, C. Membranoproliferative GN, D. Acute glomerulonephritis
B: Focal glomerulosclerosis
Answer: B: Focal glomerulosclerosis 
Explanation: Renal involvement in leprosy is related to the quantity of bacilli in the body, and the kidney is one of the target organs during splanchnic localization. In some series, all cases with borderline lepromatous and lepromatous types of leprosy have various forms of renal involvement including FSGS, mesangioproliferative glomerulonephritis, or renal amyloidosis; much less common are the renal lesions of DPGN and MPGN.