This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Increase in pyruvate and lactate is seen in which of the following deficiency? 
Select and explain. 
A. Thiamine, B. Pyridoxine, C. Niacin, D. Vitamin C
A: Thiamine
Answer: A: Thiamine 
Explanation: None