This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Thyroid Tumor, Subject name: Pathology
A 34 year old patient presented with thyroid nodule. Ultrasonography of the thyroid nodule shows foci of calcification. Histological features are shown in the diagram below, what is your likely diagnosis? 
Select and explain. 
A. Follicular carcinoma, B. Medullary carcinoma, C. Papillary carcinoma, D. Anaplastic carcinoma
C: Papillary carcinoma
Answer: C: Papillary carcinoma 
Explanation: Given histopathological slide shows branching papillae having a fibrovascular stalk covered by a single to multiple layers of cuboidal epithelial cells. These features along with given history point towards papillary carcinoma of thyroid. Nuclei of papillary carcinoma cells contain finely dispersed chromatin, which impas optically clear / empty appearance, giving rise to ground-glass nuclear appearance or Orphan annie eye nuclei. In addition, invagination of cytoplasm may give appearance of intranuclear inclusions ("pseudo-inclusions") / intranuclear grooves. These nuclear features are sufficient for diagnosis of papillary carcinoma,even in absence of papillary architecture. Concentrically calcified structures termed Psammoma bodies are often present, usually within cores of papillae.