This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti Cholinergic, Subject name: Pharmacology
Atropine is added with diphenoxylate to: 
Select and explain. 
A. Increase effect, B. Decrease side effects, C. Decrease abuse potential, D. Enhance absorption
C: Decrease abuse potential
Answer: C: Decrease abuse potential 
Explanation: Ans: C (Decrease abuse potential) Ref: Basic & Clinical Pharmacology, 2012, 12th Ed, Tala McGraw hill, Katzung BG,Masters SB, Trevor AJ.P 1095Explanation:Diphenoxylate is an opioid agonist without any analgesic property.It has Antimotilitv action hence it is used in non-infective diarrhoeaIt can cause drug dependence since it has CNS effectsAtropine in small doses (0.025 mg) is added with diphenoxylate 2.5 mg to discourage overdose since this may cause atropine side effects which unpleasant