This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Which one of the following drugs does not undergo hepatic first-pass effect ? 
Select and explain. 
A. Propranolol, B. Lidocaine, C. Insulin, D. Morphine
C: Insulin
Answer: C: Insulin 
Explanation: - Except for Insulin, all the three options undergo high first pass metabolism.