This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Sedative-Hypnotics and Parkinsonism, Subject name: Pharmacology
Pitolisant is approved for treatment of 
Select and explain. 
A. Tenosynol giant cell tumor, B. Excessive day time sleepiness in patients with narcolepsy, C. Polyneuropathy due to transthyretin amyloidosis, D. Primary myelofibrosis
B: Excessive day time sleepiness in patients with narcolepsy
Answer: B: Excessive day time sleepiness in patients with narcolepsy 
Explanation: Pitolisant is a new drug approved for treatment of excessive day time sleepiness in patients with narcolepsy. It acts as inverse agonist of H3 receptors of histamine. New drugs recently approved for conditions mentioned in options are:* Tenosynol giant cell tumor: Pexidainib* Polyneuropathy in transthyretin amyloidosis: Tafamidis meglumine* Primary and secondary myelofibrosis: Fedratinib