This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Bater syndrome, Gitelman syndrome, Liddle and Comparison with SIADH, Subject name: Medicine
All are true about Bater syndrome except? 
Select and explain. 
A. Urinary calcium increased, B. Hypokalemic alkalosis, C. Mineralocoicoid antagonist can be used., D. Normal Blood pressure
C: Mineralocoicoid antagonist can be used.
Answer: C: Mineralocoicoid antagonist can be used. 
Explanation: The defect in Bater syndrome in thick ascending limb of Loop of Henle- | urinary loss of calcium & nephrocalcinosis The salt wasting and polyuria lead to dehydration- stimulates the R.A.A.S- secondary hyperaldosteronism. This explains the hypokalemia. ROMK receptors in TAL are affected leading to urinary loss of potassium. | intra-renal prostaglandins and hence indomethacin is prescribed Secondary aldosteronism explains the development of metabolic alkalosis