This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Prenatal Diagnosis, Subject name: Gynaecology & Obstetrics
Alpha-feto-protein levels are lowered in: 
Select and explain. 
A. Down's syndrome, B. Renal anomalies, C. Anterior abdominal wall defects, D. Anencephaly
A: Down's syndrome
Answer: A: Down's syndrome 
Explanation: Decreased alpha feto proteins are seen in conditions like, Down's syndrome Intra uterine death Trophoblastic conditions Overestimated gestational age.