This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Bacteriology, Subject name: Microbiology
The most common organism responsible for gas gangrene is 
Select and explain. 
A. Clostridium perfringens, B. Clostridium difficile, C. Clostridium tetani, D. Clostridium septicum
A: Clostridium perfringens
Answer: A: Clostridium perfringens 
Explanation: C.perfringens is the predominant agent causing gas gangrene. It may occur as the sole causative agent but is more commonly seen in association with other clostridia as well as non-clostridial anaerobes. More commonly all clostridial infections do not result in gas gangrene. More commonly, they lead only to wound contamination or anaerobic cellulitis. It is the only when muscle tissue is invaded that gas gangrene results. Reference: Textbook of Microbiology; Anathanarayan and paniker's; 10th edition; Page no: 259