This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Medicine
Treatment of renal crises in scleroderma is- 
Select and explain. 
A. P-blocker, B. Losaan, C. ACE inhibitor, D. Nitrates
C: ACE inhibitor
Answer: C: ACE inhibitor 
Explanation: Scleroderma renal crisis- It presents with accelerated hypeension accompanied by acute kidney injury and progressive failure. 10% present with normal blood pressure. This is a life threatening complication of Scleroderma occurs in 10-15% of patients within 4 yrs of onset. Prior to advent ofACE-inhibitors ,sho term survival in renal crisis was <10%. urinanalysis:mild proteinuria granular casts, microscopic hematuria. Ref:Harrison 20 th edition pg no. 2555.