This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pathology
ASCOff'S bodies are seen in 
Select and explain. 
A. LIb-man sac endocarditis, B. Rheumatic hea disease, C. Bacterial endocarditis, D. Marantic endocarditis
B: Rheumatic hea disease
Answer: B: Rheumatic hea disease 
Explanation: Acute rheumatic fever is characterized by discrete inflammatory foci within a variety of tissues. The myocardial inflammatory lesions--called Aschoff bodies--are pathognomonic for rheumatic fever (Fig. 10-19, B); these are collections of lymphocytes (primarily T cells), scattered plasma cells, and plump activated macrophages called Anitschkow cells occasionally punctuating zones of fibrinoid necrosis. (Robbins Basic pathology,9th edition.pg no.391)