This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pharmacology
Digoxin toxicity is increased by all except: 
Select and explain. 
A. Renal impairment, B. Hyperkalemia, C. Hypercalcemia, D. Hypomagnesemia
B: Hyperkalemia
Answer: B: Hyperkalemia 
Explanation: Hypokalemia increases the binding of digoxin to Na-k ATPase and enhances its toxicity. Hypokalemia decreases digoxin toxicity Diuretics also interfere with the action of digoxin (REF. Essentials of medical pharmacology KD TRIPATHI 8th Edition)