This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Fluid and electrolytes, Subject name: Medicine
Effects of hypokalemia- 
Select and explain. 
A. Acidosis, B. Arrhythmia, C. Ileus of intestine, D. Polyuria
A: Acidosis
Answer: A: Acidosis 
Explanation: * The functional effects of hypokalemia on the kidney can include Na+-Cl- and HCO3- retention, polyuria, phosphaturia, hypocitraturia, and an activation of renal ammoniagenesis. Bicarbonate retention and other acid-base effects of hypokalemia can contribute to the generation of metabolic alkalosis * Hypokalemia is a major risk factor for both ventricular and atrial arrhythmias * Hypokalemia also results in hyperpolarization of skeletal muscle ,thus impairing the capacity to depolarize and contract; weakness and even paralysis may ensue. It also causes a skeletal myopathy and predisposes to rhabdomyolysis. Finally, the paralytic effects of hypokalemia on intestinal smooth muscle may cause intestinal ileus. (REF : harrisons principles of internal medicine, 19E, pg 308)