This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemical Mediators and Regulators of Inflammation, Subject name: Pathology
Vasodilatation secondary to trauma is mediated by? 
Select and explain. 
A. Histamine, B. IL-2, C. TGF-b, D. FGF
A: Histamine
Answer: A: Histamine 
Explanation: Ans. is 'a' i.e., Histamine o Principle mediators of vasodilatation in acute inflammation are Histamine, prostaglandins (PGD2, PGE2), prostacyclins, serotonin, Nitric oxide, bradykinin.