This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
The dose of Digoxin should be reduced when given along with - 
Select and explain. 
A. Quinidine, B. Rifampicin, C. Indomethacin, D. Antacids
A: Quinidine
Answer: A: Quinidine 
Explanation: Ans. is 'a' i.e., Quinidine Quinidine reduces binding of digoxin to tissue proteins as well as its renal/biliary clearance. Its plasma concentration is then doubled and toxicity may occur if dose is not reduced.