This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Medicine
Serum ACE levels are reduced in 
Select and explain. 
A. Sarcoidosis, B. COPD, C. DM, D. Hisoplasmosis
B: COPD
Answer: B: COPD 
Explanation: (B) COPD# Elevated levels of ACE are found in sarcoidosis, and are used in diagnosing and monitoring this disease.> Elevated levels of ACE are also found in leprosy, hyperthyroidism, acute hepatitis, primary biliary cirrhosis, diabetes mellitus, multiple myeloma, osteoarthritis, amyloidosis, Gaucher disease, pneumoconiosis, histoplasmosis, miliary tuberculosis.> Serum levels are decreased in renal disease, obstructive pulmonary disease, and hypothyroidism.