This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Which of the following trace element has Vitamin E sparing effect ? 
Select and explain. 
A. Copper, B. Iron, C. Magnesium, D. Selenium
D: Selenium
Answer: D: Selenium 
Explanation: Ans. is 'd' i.e., SeleniumSelenium prevents lipid peroxidation and offers protection against free radicals.Vitamin E also has the same effect (antioxidant) though by a different mechanism.Thus selenium and vitamin E supplement each other.Availability of vitamin E reduces the selenium requirment and conversely, in selenium-deficient tissue, vitamin E is depleted.