This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
Which of the following is the most common cause of clinically significant consumptive coagulopathy? 
Select and explain. 
A. Abruption placenta, B. IUCD, C. Dead fetus, D. Retained products of conception
A: Abruption placenta
Answer: A: Abruption placenta 
Explanation: One of the most common causes of clinically significant consumptive coagulopathy in obstetrics is placental abruption. Major mechanism of consumption coagulopathy are Disseminated intravascular coagulation (DIC) and to a lesser degree retroplacental bleeding. It is associated with hypofibrinogenemia (less than 150mg/dl), raised D dimer and fibrin degradation products, and low level of coagulation factors factor V, VIII.