This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.N.S, Subject name: Medicine
Shagreen patch is seen in- 
Select and explain. 
A. Tuberous sclerosis, B. Neurofibromatosis, C. Sturge weber syndrome, D. Neurofibromatosis I
A: Tuberous sclerosis
Answer: A: Tuberous sclerosis 
Explanation: . *In tuberous sclerosis skin changes include ash leaf mailed,angiofibromas, adenoma sebaceum, shagreen patches often on lower back. Ref Harrison20th edition pg 2564