This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
Uterine blood flow at term is? 
Select and explain. 
A. 800-1200 ml/min, B. 50-70 ml/min, C. 175-200 ml/min, D. 500-750 ml/min
D: 500-750 ml/min
Answer: D: 500-750 ml/min 
Explanation: The massively increased uterine blood flow necessary to maintain pregnancy is made possible by significant hyperophy and remodeling of all pelvic vessels. After delivery, their caliber diminishes to approximately the size of the pre pregnant state. Uterine blood flow is increased from 50 ml/min in non pregnant states to about 750 ml near term. The increase is due to the combined effect of utero-placental an feto-placental vasodilation. The vasodilation is due to smooth muscle relaxing effects of progesterone, oestrogen, nitric oxide, prostaglandins and ANP. Ref: Cunningham F.G., Leveno K.J., Bloom S.L., Hauth J.C., Rouse D.J., Spong C.Y. (2010). Chapter 30. The Puerperium. In F.G. Cunningham, K.J. Leveno, S.L. Bloom, J.C. Hauth, D.J. Rouse, C.Y. Spong (Eds), Williams Obstetrics, 23e.