This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of carbohydrate, Subject name: Biochemistry
Gluconeogenesis takes place in 
Select and explain. 
A. Liver, B. RBC, C. Adipocyte, D. Myocyte
A: Liver
Answer: A: Liver 
Explanation: Only liver can replenish blood glucose through gluconeogenesis because glucose-6phosphatase is present mainly in liver. So liver plays the major role in maintaining the blood glucose level.Ref: DM Vasudevan, 7th edition, page no: 118