This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pharmacology, Subject name: Pharmacology
Pharmacokinetic characteristics of propranolol include Vd = 300 L/70 kg, C1 = 700 mL/min, and oral bioavailability f = 0.25. What is the dose needed to achieve a plasma level equivalent to a steady state level of 20 mg/L? 
Select and explain. 
A. 4 mg, B. 12 mg, C. 24 mg, D. 48 mg
C: 24 mg
Answer: C: 24 mg 
Explanation: LD = 300L x 20 mg/L / 0.25 = 6000 mg/0.25 = 24,000 mg or 24 mg Ref:- kd tripathi; pg num:-33