This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
Epithelial granuloma is caused by - 
Select and explain. 
A. Neutrophil, B. Cytotoxic T cells, C. Helper T cells, D. NK cells
C: Helper T cells
Answer: C: Helper T cells 
Explanation: Granuloma formation is a type IV hypersensitivity reaction mediated by helper T cells. This reaction is similar to caseating granuloma formation in TB Basic Pathology, Robbins. Page no.: 56