This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Larynx, Subject name: ENT
Antibiotic of choice for acute epiglottitis is: 
Select and explain. 
A. Tetracycline, B. Chloramphenicol, C. Cephalosporin, D. Penicillin
C: Cephalosporin
Answer: C: Cephalosporin 
Explanation: Earlier ampicillin has been the drug of choice. Now cephalosporins of second and third generations (cefuroxime, cefotaxime and ceftriaxone) are preferred. Chloramphenicol is also effective but is more toxic compared to cephalosporins.