This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Structure and function of protein, Subject name: Biochemistry
Glucose-6 Phosphatase deficiency is seen in 
Select and explain. 
A. Von Gierke disease, B. Tay sach disease, C. Pompe disease, D. Anderson disease
A: Von Gierke disease
Answer: A: Von Gierke disease 
Explanation: NameEnzyme DeficiencyClinical FeaturesVon Gierke diseaseGlucose-6-phosphataseGlycogen accumulation in liver and renal tubule cells;hypoglycemia; lactic acidemia; ketosis; hyperlipemiaRef: Harper&;s Biochemistry; 30th edition; Chapter 18 Metabolism of Glycogen; Page no: 179