This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Physiology
Albinism is due to: 
Select and explain. 
A. Marked deficiency of melanin pigment, B. Thymus disorder, C. Tumour of pineal gland, D. ACTH deficiency
A: Marked deficiency of melanin pigment
Answer: A: Marked deficiency of melanin pigment 
Explanation: deficiency of melanin pigment results in a marked deficiency of pigment in eyes, hair and skin Ref: guyton and hall textbook of medical physiology 12 edition page number: 550,551,552