This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Autosomal recessive kidney disease is caused due to mutation in: 
Select and explain. 
A. Fibrocystin, B. Polycystin-1, C. Polycystin-2, D. All of the above
A: Fibrocystin
Answer: A: Fibrocystin 
Explanation: Autosomal dominant polycystic kidney disease is caused by mutations in: The PKD1 gene encodes a large (460-kD) integral membrane protein named polycystin-1 The PKD2 gene product polycystin-2 Autosomal recessive kidney disease is caused due to mutation in PKHD1 gene coding for fibrocystin. Ref: Robbins 8th edition Chapter 20.