This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Intracranial Space Occupying Lesion, Subject name: Medicine
Schwannoma of spinal nerve roots is seen in? 
Select and explain. 
A. Neurofibromatosis 1, B. Neurofibromatosis 2, C. Turcot syndrome, D. Li - Fraumeni syndrome
A: Neurofibromatosis 1
Answer: A: Neurofibromatosis 1 
Explanation: Schwannoma is a benign tumor arising from Schwann cells of cranial and spinal nerve roots. NF-1 is associated with an increased incidence of schwannomas of spinal nerve roots. MC schwannoma is vestibular schwannoma or acoustic neuroma arises from vestibular poion of 8th cranial nerve. Patients with NF-2 have an incidence of vestibular schwannomas that are frequently bilateral.