This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
Which of the following is the most likely inheritance pattern in the pedigree given below – 
Select and explain. 
A. Autosomal dominant, B. Mitochondrial, C. Autosomal recessive, D. X–linked dominant
D: X–linked dominant
Answer: D: X–linked dominant 
Explanation: It is an X-linked dominant pattern of inheritance.
The features which suggest the X-linked dominant pattern of inheritance are-
A single abnormal X chromosome is sufficient to express the disease.
All of the female offsprings of a diseased male XY will receive the abnormal X chromosome and express the disease, whereas none of the male offspring to the deceased father will have the disease (as sons don't receive X chromosome from their father).
A diseased mother can transmit the abnormal X chromosome to both daughter and sons equally.