This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Testis and scrotum, Subject name: Surgery
Placental alkaline phosphates is marker of: 
Select and explain. 
A. Theca cell tumour, B. Teratoma, C. Choriocarcinoma, D. Seminoma
D: Seminoma
Answer: D: Seminoma 
Explanation: PLAP-most useful marker for bulk disease. Tumour marker for seminoma is PLAP. BETA HCG is also raised in 5-10% of pure seminomas as they contain syncytiotrophoblast like giant cells.