This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Medical, surgical and gynaecological illness complicating pregnancy, Subject name: Gynaecology & Obstetrics
False statement regarding cholestasis in pregnancy: 
Select and explain. 
A. Recurs In subsequent pregnancy, B. Ursodeoxycholic acid relieves pruritus, C. Mild jaundice occurs in majority of patients, D. Pruritus may precede laboratory findings
D: Pruritus may precede laboratory findings
Answer: D: Pruritus may precede laboratory findings 
Explanation: Recurrence is common in subdequent pregnancies (90%)and with the use of oestrogen containing oral contraceptivr pills.Such patients are at risk for chronic liver disease and should be closely followed up aftet pregnancy. Refer page no 280 of Text book of obsteics,sheila balakrishnan,2 nd edition. OR Reccurence rate is high(50-60%) Cholestyramine is effective for itching. Jaundice is slight. REference: Textbook of Duttas ,9th edition,page 271