This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Early complement deficiency can manifest as? 
Select and explain. 
A. Hereditary angioneurotic edema, B. Atypical HUS, C. SLE, D. PNH
C: SLE
Answer: C: SLE 
Explanation: Deficiency of C1,C2,C4 (early complement deficiency) can manifest as SLE and other collagen vascular disorders.