This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
Gama globulins are synthesized in ? 
Select and explain. 
A. Liver, B. Lung, C. Plasma cells, D. Spleen
C: Plasma cells
Answer: C: Plasma cells 
Explanation: Ans. is 'c' i.e., Plasma cells Gamma globulins (immunoglobulins) are synthesized by plasma cells. Plasma cells Plasma cells are the antibody secreting cells On contact with its appropriate antigen, the mature B cell undergoes clonal proliferation. The majority of activated B cells are transformed into plasma cells and secrete antibodies. Plasma cells make an antibody of a single specificity, of a single immunoglobulin class and allotype,and of a single light chain type only. An exception is seen in the primary antibody response, when a plasma cell producing Ig M initially, may later be switched to Ig G production. While plasma cell is the best antibody producing cell, lymphocytes, lymphoblasts and transitional cells may also synthesise Ig to some extent.