This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hematology, Subject name: Pharmacology
Vascular dermal necrosis is seen with 
Select and explain. 
A. Warfarin, B. Hirudin, C. Dabigatran, D. Rivaroxiban
A: Warfarin
Answer: A: Warfarin 
Explanation: Vascular dermal necrosis occurs due to warfarin Cutaneous necrosis with reduced activity of protein C sometimes occurs during the first weeks of therapy. Rarely, the same process causes frank infarction of the breast, fatty tissues, intestine, and extremitiesKatzung 12e pg: 610