This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti-Cancer, Subject name: Pharmacology
Hand foot syndrome is seen with which anticancer drug? 
Select and explain. 
A. Cisplatin, B. 5-fluorouracil, C. Methotrexate, D. Imatinib
B: 5-fluorouracil
Answer: B: 5-fluorouracil 
Explanation: Ans. B. 5-fluorouracilHand and foot syndrome is caused by 5-fluorouracil, capecitabine, doxorubicin. Cisplatin is highly emetic and nephrotoxic drug. Methotrexate is hepatotoxic.