This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Carbohydrates, Subject name: Biochemistry
Beta-glucosidase is defective in which disease? 
Select and explain. 
A. Gaucher's disease, B. Tay-Sachs disease, C. Galactosaemia, D. DM
A: Gaucher's disease
Answer: A: Gaucher's disease 
Explanation: Ans. a (Gaucher's disease). (Ref: Harper, Biochemistry, 25th ed., 267)Sphingolipidoses DiseaseInheritanceEnzymeCNS involvementVisceral involvement1FabryXLRAlpha-galactosidase-+2Krabbe'sARBeta-galactosidase+(bilateral thalami)+3FarberARCeramidase+/--4GaucherARBeta-Glucosidase+/-+5MetachromaticleukodystrophyARAryl sulfatase+ (Diffuse White matter)-6Niemann-PickARSphigomyelinase++7Tay-SachsARHexosaminidase A+-8SandhoffARHexosaminidase A, B++