This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
All of the following drugs are used in the medical termination of early pregnancy, EXCEPT: 
Select and explain. 
A. Methotrexate, B. Mifepristone, C. Misoprostol, D. Medroxyprogesterone
D: Medroxyprogesterone
Answer: D: Medroxyprogesterone 
Explanation: Medroxyprogesterone is not indicated in the termination of pregnancy. The three medications used in the medical termination of pregnancy are methotrexate, misoprostol and mifepristone. Mifepristone and methotrexate acts by increasing uterine contractility by reversing the progesterone induced inhibition of contractions and misoprostol acts by stimulating the myometrium. Medroxyprogesterone is used in the treatment of abnormal uterine bleeding, amenorrhea, contraception, endometriosis, endometrial hyperplasia and endometrial carcinoma. Medroxyprogesterone acts by suppressing ovulation, causing endometrial thinning, and forming thick cervical mucus. Ref: Cunningham F.G., Leveno K.J., Bloom S.L., Hauth J.C., Rouse D.J., Spong C.Y. (2010). Chapter 9. Aboion. Lippincott's Drugs to Know for the NCLEX-RN page 350.