This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous Questions, Subject name: Medicine
Which component of cigarette smoke is responsible for C.A.D? 
Select and explain. 
A. Nicotine, B. Tar, C. Polycyclic aromatic hydrocarbons, D. Benzene
D: Benzene
Answer: D: Benzene 
Explanation: Cigarette smoke product Effect on human body Acetaldehyde/ Anabasine Addiction Benzene Carcinogenic + cardio-toxic + reproductive potential toxicity Benzopyrene Carcinogenic Carbon monoxide Reproductive potential toxicity Vinyl chloride Carcinogenic