This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Transcription, Subject name: Biochemistry
All of the following are DNA binding domains found in transcription factors, EXCEPT 
Select and explain. 
A. Zinc finger, B. Helix-turn-Helix, C. Helix-loop-helix, D. Basic domains
C: Helix-loop-helix
Answer: C: Helix-loop-helix 
Explanation: DNA binding domains found in transcription factors DNA binding domains in transcription factors Zinc finger Helix-turn-Helix Basic domains Helix-loop-helix (HLH) Dimerisation domain, Not DNA-binding domain. Proteins with HLH also contains a separate DNA binding domain made up of basic amino acids. E.g. Hypoxia-inducible factor (HIF) MyoD MITF (Microphthalmia-associated transcription factor)