This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Anatomy
Drug induced poal hypeension is seen with 
Select and explain. 
A. Vitamin A toxicity, B. Methotrexate, C. Aldomet, D. Hydatid cyst
A: Vitamin A toxicity
Answer: A: Vitamin A toxicity 
Explanation: Vitamin A induced Hepatotoxicity Normal dose of vitamin A are not associated with liver injury or liver test abnormalities, but higher doses can be toxic Mechanism of injury : Excess Vitamin A is stored in stellate cells in the liver and accumulation can lead to their activation and hyperophy, excess collagen production, fibrosis and liver injury Serum bilirubin is typically only mildly elevated Liver biopsy is diagnostic Ref: Internet sources