This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
APC gene exes its effect in combination with which of the following 
Select and explain. 
A. Beta catenin, B. E cadherin, C. Alpha catenin, D. BCX
A: Beta catenin
Answer: A: Beta catenin 
Explanation: Regulation of beta-catenin preventsgenes that stimulate cell division from being turned on too often and prevents cell overgrowth. The humanAPC gene is located on the long (q) arm of chromosome 5 in band q22.2 (5q22.2). The APC gene has been shown to contain an internal ribosome entry site. Refer robbins