This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
Antiplatelet drug acting via purinergic receptors, not largely impacted by CYP2C19 polymorphism is: 
Select and explain. 
A. Ticlopidine, B. Prasugrel, C. Clopidogrel, D. Abciximab
B: Prasugrel
Answer: B: Prasugrel 
Explanation: Ref. KDT. Page. 629
Prasugrel is a prodrug , similar to Clopidogrel

Thienopyridine drug class
Irreversible antagonist of P2Y12 ADP receptors
Rapidly absorbed, completely activated & exerts more consistent platelet inhibition. No interaction with CYP2C19 polymorphism
Strong anti-platelet activity
Bleeding complications are more serious and frequent.
Contraindicated in patients with history of ischemic strokes and TIA’s