This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Urinary tract, Subject name: Pathology
Renal cell carcinoma- 
Select and explain. 
A. Invades Renal Vein, B. Hematuria usually absent, C. Arises from proximal convoluted tubule, D. More common in females
A: Invades Renal Vein
Answer: A: Invades Renal Vein 
Explanation: RCC commonly arise from the poles of the kidney as a solitary and unilateral tumor,more often in upper pole.The tumor has slight male preponderance(2:1).One significant characteristic is the presence of tumor thrombus in the renal vein which may extend into the vena cava.The clinical features include a triad of gross hematuria ,flank pain,palpable abdominal mass. From Textbook of pathology HarshMohan ,7th edition pg no:681,682