This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Polycystic Kidney Disease, Subject name: Pathology
PKD1 gene which encodes polycystin-1 protein which is involved in cell-cell and cell-matrix interactions, is located on which chromosome? 
Select and explain. 
A. 17, B. 1, C. 16, D. 13
C: 16
Answer: C: 16 
Explanation: PKD1 gene is located on chromosome 16p13.3. It encodes a large (460-kD) integral membrane protein named polycystin-1.