This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
Self-stimulation is experimentally done from which pa of brain 
Select and explain. 
A. Medial forebrain bundle, B. Area around aqueduct of sylvius, C. PV region of hypothalamus, D. Radical radiotherapy
A: Medial forebrain bundle
Answer: A: Medial forebrain bundle 
Explanation: Ans. a. Medial forebrain bundleMedial forebrain bundle is one of the areas responsible for self-stimulationResponsible Centres for Self-stimulationVentral tegmentumdegMedial forebrain bundleQNucleus accumbensQFrontal coex0Drugs that block post-synapticin creases it. The main site D3 receptors dopaminergic reduces the rate of self-stimu ation. Dopamine agonist of the relevant receptor is the nucleus accumbens located at striatum base.