This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti-HIV Drugs, Subject name: Pharmacology
Which of the following drugs inhibits post-translational modification of viral proteins? 
Select and explain. 
A. Indinavir, B. Enfuviide, C. Lamivudine, D. Zalcitabine
A: Indinavir
Answer: A: Indinavir 
Explanation: - PROTEASE INHIBITORS inhibits post-translational modification of viral proteins.- These include drugs like: INDINAVIR RITONAVIR LOPINAVIR AMPRENAVIR FOS-AMPRENAVIR ATAZANAVIR (Lowest risk of Lipodystrophy syndrome but can cause hyperbilrubinemia) SAQUINAVIR NELFINAVIR - These are metabolized by CYP3A4 and are CYP3A4 inhibitors themselves (Ritonavir Boosting - boost the other inhibitors)- These drugs can cause LIPODYSTROPHY SYNDROME: | GLUCOSE | LIPIDS INSULIN RESISTANCE WT. GAIN. It is also caused by Atypical Antipsychotics.