This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pathology
The characteristic lesion of atherosclerosis is 
Select and explain. 
A. Fibrinoid necrosis of the media, B. Giant cell reaction in the retina and internal elastic lamina, C. Organised thrombus in the affected segment, D. 'Fibro-fatty' lesion in the intima of the blood vessels
D: 'Fibro-fatty' lesion in the intima of the blood vessels
Answer: D: 'Fibro-fatty' lesion in the intima of the blood vessels 
Explanation: Atherosclerosis is a intima based lesion composed of a fibrous cap and an atheromatous core: the constituents of the plaque include smooth muscle cells, ECMs, inflammatory cells, lipids and necrotic debris Robbins 9th edition page no 343