This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pathology
Orphan annie eye nuclei appearance is characteristic of- 
Select and explain. 
A. Papillary carcinoma thyroid, B. Carcinoma pituitary, C. Paraganglioma, D. Meningioma
A: Papillary carcinoma thyroid
Answer: A: Papillary carcinoma thyroid 
Explanation: Orphan Annie eye nuclei is a feature of papillary carcinoma of thyroid. The nuclei of cells in papillary carcinoma thyroid has finely dispersed chromatin . Thus it is optically clear and shows ground glass or Orphan Annie eye nuclei. Ref: Robbins and cotrans 9e Pg 1095