This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.N.S, Subject name: Pharmacology
Which drug is given in the pain due to diabetic neuropathy? 
Select and explain. 
A. Lamotrigine, B. Na valproate, C. Gabapentin, D. Morphine
C: Gabapentin
Answer: C: Gabapentin 
Explanation: Ans. is 'c' i.e., Gabapentin Gabapentin* This is lipophilic GABA derivatve.* Gabapentin enhances GABA release but itself does not act as a agonist at the GABAA receptor.* It crosses to the brain and enhances GABA release but does not act as agonist at GABAA receptor.* Gabapentin is considered to be a first line drug for pain due to diabetic neuropathy and postherpetic neuralgia.Usesi) GTCS and partial seizuresii) Postherpetic neuralgiaiii) Pain due to diabetic neuropathyiv) Prophalaxis of migraine