This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
In women having PCOD with irregular menstrual cycles, combined oral contraceptive pills 
Select and explain. 
A. Increase sex hormone binding globulin, B. Cause endometrial hyperplasia, C. Increases lutenizing hormone, D. Increase insulin
A: Increase sex hormone binding globulin
Answer: A: Increase sex hormone binding globulin 
Explanation: In combined OCPS, estrogen component increases levels of SHBG, which binds free androgen.