This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
Maximum risk to foetus occurs when maternal infection with rubella occurs during which of the following time: 
Select and explain. 
A. 6-12week, B. 12-l8week, C. 14-20week, D. 20-24week
A: 6-12week
Answer: A: 6-12week 
Explanation: Ans. (a)6-12week In general, the earlier in pregnancy infection occurs, the greater the damage to the fetus. Maximum damage to the fetus occurs when infection is acquired in the first trimester of pregnancy.During acute rubella in pregnancy, the rate of congenital infection is over 90% in the 12 first weeks of pregnancy, approximately 60% in weeks 13 to 17, 25% in weeks 18 to 24 and then increases again during the last month of pregnancy