This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
All of the following are true for patients of ulcerative colitis associated with primary sclerosing cholangitis (PSC), EXCEPT: 
Select and explain. 
A. They may develop biliary cirrhosis, B. May have raised alkaline phosphatase, C. Increased risk of hilar Cholangiocarcinoma, D. PSC reves after a total colectomy
D: PSC reves after a total colectomy
Answer: D: PSC reves after a total colectomy 
Explanation: Colectomy for colitis makes no difference to the course of primary sclerosing cholangitis. Inpatients with associated ulcerative colitis the course of each disease seems independent of the other. Ref: Schwaz Principles of Surgery, 8th Edition, Page 1210