This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Which of the following is a prokinetic drug? 
Select and explain. 
A. Domperidone, B. Cimetidine, C. Ondansetron, D. Hyoscine
A: Domperidone
Answer: A: Domperidone 
Explanation: Ans. is 'a' i.e., Domperidone Gastrokinetic (prokinetic drugs) These are the drugs which promote gastrointestinal transit and speed gastric emptying by enhancing coordinated propulsive motility. Prokinetic drugs are - Metoclopramide, Domperidone, Cisapride, Mosapride, Tegaserod, renzapride, prucalopride. Prokinetic drugs can act by ? 5HT4 agonistic activity D2 and 5-HT3 antagonistic activity Both these actions will increase the release of Ach and thereby motility of GIT.