This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Physiological antagonism is found in: 
a) Isoprenaline and salbutamol
b) Isoprenaline and adrenaline
c) Isoprenaline and propranolol
d) Adrenaline and histamine
e) Salbutamol and leukotrienes 
Select and explain. 
A. ab, B. cd, C. ac, D. de
D: de
Answer: D: de 
Explanation: Physiological antagonists are those drugs that produce opposite action by acting on different receptors.
Adrenaline reverses the bronchoconstrictor action of histamine (via. H1 receptors) by cauing bronchodilation (through β2 receptors). Therefore, these are physioIogical antagonists.