This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Pharmacology
A drug that blocks the uptake of dopamine and norepinephrine into presynaptic nerve terminals and also blocks sodium channels in the axonal membrane is : 
Select and explain. 
A. Cocaine, B. Ephedrine, C. Imipramine, D. Fluoxetine
A: Cocaine
Answer: A: Cocaine 
Explanation: Cocaine is a local anaesthetic agent (acts by inhibiting Na+channel in the axonal membrane) that also possesses indirect sympathomimetic activity. It increases sympathetic tone, causes local vasoconstriction, marked rise in BP and tachycardia. It is the only L.A which causes vasoconstriction while others causes vasodilation.