This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Interstitial Lung Disease, Subject name: Medicine
Bronchocentric granulomatosis commonly occurs due to? 
Select and explain. 
A. Hypersensitivity reaction to Aspergillus, B. Immunological reaction to HIV, C. Damage by c- ANCA, D. Damage by p-ANCA
A: Hypersensitivity reaction to Aspergillus
Answer: A: Hypersensitivity reaction to Aspergillus 
Explanation: Bronchocentric Granulomatosis is characterized by peri-bronchial necrotising granulomatous inflammation. It occurs due to: Hypersensitivity reaction to Aspergillus in patients with asthma. In patients without asthma, rheumatoid ahritis and infections like TB are associated. Immunological reaction to HIV virus leads to lymphocytic interstitial pneumonitis.