This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Other topics and Adverse effects, Subject name: Pharmacology
All of the following drugs can cause cholestatic jaundice EXCEPT: 
Select and explain. 
A. Erythromycin estolate, B. INH, C. OC pills, D. Chlorpromazine
B: INH
Answer: B: INH 
Explanation: The above drugs erythromycin, oc pills, chlorpromazine effects the liver and damage it leading to cholestasis. Mostly because all these drugs are metabolized and excreted bile and hence during bile formation, they damage the liver but isoniazid an antitubercular drug is extensively metabolized in liver but excreted in the urine. It mostly induces peripheral neuritis rather than cholestatic jaundice ESSENTIALS of medical PHARMACOLOGY SEVENTH EDITION -K D TRIPATHI Page:753,321,766.413