This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
Endometrial carcinoma: which of the following tumor suppressor gene occur - 
Select and explain. 
A. P53, B. Rb, C. PTEN, D. APC
C: PTEN
Answer: C: PTEN 
Explanation: Harshmohan textbook of pathology 7th edition. endometrial hypreplasia is a forerunner of endometrioid cancer is suppoed by mutated PTEN gene located on chromosome no 10. Seen in 20% of cases of complex hyperplasia while it is seen in 40 to 80% of cases of endometriosis carcinoma. .