This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Nottingham Histologic score doesn't include? 
Select and explain. 
A. Tubule formation, B. Nuclear pleomorphism, C. Mitotic rate, D. Presence or absence of mets.
D: Presence or absence of mets.
Answer: D: Presence or absence of mets. 
Explanation: Nottingham Histologic score is used for grading invasive carcinoma of breast. 
Option a, b and c are used to calculate the score.