This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
In psoriatic ahritis, if the patient has liver fibrosis, ahropathy can NOT be treated with? 
Select and explain. 
A. Methotrexate, B. Anti-TNF-alpha agents, C. Steroids, D. Sulfasalazine
A: Methotrexate
Answer: A: Methotrexate 
Explanation: Methotreaxte is absolutely contraindicated in liver fibrois. In case of treatment for long duration liver fibrosis should be assessed by liver biopsy.