This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Autonomic nervous system, Subject name: Pharmacology
Urination in the human subject is decreased by 
Select and explain. 
A. Nicotinic agonists, B. AChase inhibitors, C. muscarinic agonists, D. muscarinic antagonists
D: muscarinic antagonists
Answer: D: muscarinic antagonists 
Explanation: ANTICHOLINERGIC DRUGS (Muscarinic receptor antagonists, Atropinic, Parasympatholytic) Smooth muscles:- All visceral smooth muscles that receive parasympathetic motor innervation are relaxed by atropine (M3 blockade). Tone and amplitude of contractions of stomach and intestine are reduced; the passage of chyme is slowed--constipation may occur, spasm may be relieved. Atropine has relaxant action on ureter and Urinary bladder; urinary retention can occur in older males with prostatic hyperophy. However,this relaxant action can be beneficial for increasing bladder capacity and controlling detrusor hyperreflexia in neurogenic bladder/enuresis. Ref:- kd tripathi; pg num:-114,115