This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Anatomy
Smudge cells in the peripheral smear are characteristic of: 
Select and explain. 
A. Chronic myelogenous leukemia, B. Chronic lymphocytic leukemia, C. Acute myelogenous leukemia, D. Acute lymhoblastic leukemia
B: Chronic lymphocytic leukemia
Answer: B: Chronic lymphocytic leukemia 
Explanation: In CLL the peripharal blood contains increased number of small round lymphocytes with scant cytoplasm. These cells are fragile and are frequently disrupted in the process of making smears,producing so called smudge cells.(ref Robbins 7th/673)