This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of nucleic acids, Subject name: Biochemistry
True about silent mutation in gene 
Select and explain. 
A. No change in mRNA, B. No change in Amino acid sequence in protein, C. No expression of protein, D. No change in expression of protein
B: No change in Amino acid sequence in protein
Answer: B: No change in Amino acid sequence in protein 
Explanation: a point mutation may change the codon for one amino acid to a synonym for the same amino acid Thus the mutation is silent and has no effect on the phenotype For example CUA is mutated to CUC both code for leucine and so this mutation has no effectRef: DM Vasudevan, 7th edition, page no: 613