This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Physiology
Which one of the following is a potent stimulus for the production of erythropoietin? 
Select and explain. 
A. Alpha interferon, B. Interleukin-3, C. Hypoxia, D. Hypercarbia
C: Hypoxia
Answer: C: Hypoxia 
Explanation: Hypoxia oring the production of hemoglobin F both direct effects on globin gene expression, as well as up-regulated production of erythropoietin. Ref: Ganong's Review of Medical Physiology Twenty-Third Edition Page No:526