This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Autonomic nervous system, Subject name: Pharmacology
Anticholinesterases with effect on CNS is 
Select and explain. 
A. Neostigmine, B. Pyridostigmine, C. Physostigmine, D. Edrophonium
C: Physostigmine
Answer: C: Physostigmine 
Explanation: Refer kDT 6/e p 101 Because it enhances the transmission of acetylcholine signals in the brain and cancross the blood-brain barrier,physostigmine salicylate is used to treat anticholinergic poisoning (that is, poisoning by substances that interfere with the transmission of acetylcholine signaling, such as atropine, scopolamine,