This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Amyloidosis, Subject name: Pathology
Lardaceous spleen is due to deposition of amyloid in: 
Select and explain. 
A. Sinusoids of red pulp, B. White pulp, C. Pencillary aery, D. Splenic trabeculae
A: Sinusoids of red pulp
Answer: A: Sinusoids of red pulp 
Explanation: Amyloidosis of the spleen may be inapparent grossly or may cause moderate to marked splenomegaly (up to 800 g). Two patterns of deposition is seen:- The deposits limited to the splenic follicles, producing tapioca-like granules on gross inspection, designated sago spleen. The deposits involves the red pulp,Fusion of the early deposits gives rise to large, maplike areas of amyloidosis, creating what has been designated lardaceous spleen.