This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Liver & Biliary Tract, Subject name: Pathology
False about Criggler najar syndrome? 
Select and explain. 
A. Absence of UDPG enzyme, B. Normal liver biopsy, C. Conjugated hyperbilirubinemia, D. Type 1 is more severe
C: Conjugated hyperbilirubinemia
Answer: C: Conjugated hyperbilirubinemia 
Explanation: Ans. is 'c' i.e., Conjugated hyperbilirubinemia Criggler-Najjar Syndrome* CN syndrome is a congenital unconjugated hyperbilirubinemia. Basic defect is either reduced or absent UDPG transferase.* There are two types of CN syndrome:-1) Type I# It is an autosomal recessive disorder in which UDPG transferase is absent. Thus phenobarbitone has no effect (as enzyme is absent).# It is more severe hyperbilirubinemia than type II. There may be kernicterus. LFTs and liver histology are normal.2) Type II# It is an autosomal dominant disorder in which UDPG transferase is reduced. Phenobarbitone can reduce unconjugated Bilirubin by inducing UDPG transferase.# LFTs and liver histology are normal and there is no kernicterus