This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Neuromuscular Blocker, Subject name: Anaesthesia
The clinically relevant dose of neuromuscular blocker required for clinically useful relaxation corresponds to:- 
Select and explain. 
A. ED50, B. ED75, C. ED95, D. ED25
C: ED95
Answer: C: ED95 
Explanation: The effect of neuromuscular blocking drugs is measured as the depression of adductor muscle contraction (twitch) following electrical stimulation of the ulnar nerve. The value is compared with a control value obtained before injection of the drug. According to Miller, potency of a NMBD is best described as the effective dose - "The dose of a neuromuscular blocking drug required to produce an effect (e.g., 50%, 90%, or 95% depression of twitch height, commonly expressed as ED50, ED90, and ED95, respectively". Thus, the ED95 is the amount of NMBD required to reduce twitch height by 95% i.e . clinically useful relaxation