This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Which of the following disorders is least likely associated with progression to lymphoma 
Select and explain. 
A. Sjogren's syndrome, B. Araxia telangiectasia, C. Severe combined immunodeficiency, D. Lynch II syndrome
C: Severe combined immunodeficiency
Answer: C: Severe combined immunodeficiency 
Explanation: Ans. is 'c' i.e., Severe combined immunodeficiency Choice Cancers associated Sjogren syndrome NHL mainly MALT-oma involving salivary glands>stomach Ataxia telengectasia Elevated incidence of cancers, approximately 100-fold in comparison to the general population. In children, more than 85% of neoplasm cases are acute lymphocytic leukemia or lymphoma. In adults with ataxia-telangiectaisa, solid tumors are more frequent Lynch-II syndrome Gastrointestinal cancer associated with endometrial/ovarian carcinoma. Early onset brain tumor and lymphoma also seen in children