This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
The principal precursor of cholesterol is - 
Select and explain. 
A. Citrate, B. Acetate, C. Glycerol, D. Lanosterol
B: Acetate
Answer: B: Acetate 
Explanation: Acetate

All carbon atoms of cholesterol are derived from acetyl-CoA (activated acetate).

"Cholesterol is a C-27 compound. All its carbon atoms are provided by a single precursor, acetate". — Essential of biochemistry