This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Diabetes, Subject name: Pathology
An elderly male patient presented with blurring of vision. Fundus examination revealed cotton wool spots on retina and systemic examination showed decreased peripheral sensations and increased urine output. What finding is the following renal biopsy showing? 
Select and explain. 
A. Kimmelstien Wilson lesion, B. Amyloid deposits, C. Crescents, D. Hyaline atherosclerosis
A: Kimmelstien Wilson lesion
Answer: A: Kimmelstien Wilson lesion 
Explanation: - Given histopathological slide is showing Kimmelstein Wilson/ Nodular Glomerulosclerosis which is pathognomic of diabetic nephropathy. - OTHER FEATURES OF DIABETIC NEPHROPATHY: - Glomerular lesions like Capillary basement membrane thickening - earliest & most common change in DN Diffuse mesangial sclerosis - presents as nephrotic syndrome in severe cases - Renal vascular lesions, principally aeriolosclerosis - Pyelonephritis, including necrotizing papillitis. - Diabetic microangiopathy which causes thickening of small blood vessels & leaky underlies development of diabetic nephropathy, retinopathy & some forms of neuropathy.