This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Patient who is on indinavir treatment presented with jaundice. On detailed evaluation is is found that the elevated bilirubin is mainly indirect fraction. The probable mechanism of indirect hyperbilirubinemia in this setting would be: 
Select and explain. 
A. Increased bilirubin production, B. Decreased hepatocellular uptake, C. Decreased conjugation, D. Hemolysis
C: Decreased conjugation
Answer: C: Decreased conjugation 
Explanation: Unconjugated Hyperbilirubinemia Increased bilirubin production Eg: hemolysis, ineffective erythropoiesis, blood transfusion, resorption of hematomas) Decreased hepatocellular uptake eg: drugs such as rifampin, Gilbe's syndrome ) Decreased conjugation Eg:Gilbe's syndrome, Crigler-Najjar syndrome, physiologic jaundice of the newborn, drugs such as indinavir, atazanavir) Ref:Sleisenger and Fordtran's,E-9,P-325