This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
A cell cycle specific anticancer drug that acts mainly in the M phase of the cycle is: 
Select and explain. 
A. Cisplatin, B. Etoposide, C. Methotrexate, D. Paclitaxel
D: Paclitaxel
Answer: D: Paclitaxel 
Explanation: Vinca alkaloids (Vincristine, Vinblastine and Vinorelbine) and taxanes (Paclitaxel and Docetaxel) act on M-phase of the cell cycle.
Vinca alkaloids inhibit the formation whereas taxanes inhibit the breakdown of the mitotic spindles.