This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Carbohydrates, Subject name: Biochemistry
Severe thiamine deficiency is associated with: 
Select and explain. 
A. Decreased RBC transketolase activity, B. Increased clotting time, C. Decreased RBC transaminase activity, D. Increased xanthic acid excretion
A: Decreased RBC transketolase activity
Answer: A: Decreased RBC transketolase activity 
Explanation: Ans. A Decreased RBC transketolase activity(Ref: Harper 31/e page 185)Thiamine is a coenzyme of Erythrocyte transketolase so its activity is decreased if Thiamine deficiency