This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunology and Rheumatology, Subject name: Medicine
Charcot arthropathy most commonly seen in: 
Select and explain. 
A. DM, B. Syringomyelia, C. Leprosy, D. Rheumatoid arthritis
A: DM
Answer: A: DM 
Explanation: Ans. a. DMCharcot arthropathy is the destruction of bone and soft tissues at weight bearing joints.Diabetes is the most common etiology of Charcot arthropathy.It occurs most commonly in the lower extremity, at the foot and ankleIts most severe form can disruption of the bony architecture.