This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology and breast, Subject name: Surgery
MEN-1 include all except 
Select and explain. 
A. Prolactiomas, B. Parathyroid hyperplasia, C. Pancreatic endocrine tumours, D. Medullary carcinoma thyroid
D: Medullary carcinoma thyroid
Answer: D: Medullary carcinoma thyroid 
Explanation: MEN 1 is characterised by the triad of tumours in the anterior pituitary gland, mostly presenting as prolactinomas or non-functioning tumours, hyperplasia of the parathyroids causing primary hyperparathyroidism (pHPT) and Pancreaticoduodenal endocrine tumours (PETs). also called Wermer's syndrome. It is caused by germline mutations in the menin gene, located on chromosome 11.MEN 2A is characterised by the combination of MTC, pHPT and mostly bilateral phaeochromocytomas. MTC combined with phaeochromocytoma alone is called Sipple's syndromeMEN 2B comprises MTC, phaeochromocytoma and characteristic facial and oral mucosal neurinomas and intestinal ganglioneuromatosis, accompanied by a Marfanoid habitus.Ref: Bailey and Love 27e pg: 856