This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Sickle Cell Disease, G6PD deficiency and other Hemolytic Anemia, Subject name: Medicine
Basophilic stippling in RBC is due to which enzyme deficiency? 
Select and explain. 
A. Pyruvate kinase, B. G6PD, C. Glutathione synthase, D. Pyrimidine 5 nucleotidase
D: Pyrimidine 5 nucleotidase
Answer: D: Pyrimidine 5 nucleotidase 
Explanation: Basophilic stippling is because of RNA residual in RBC Defect in Pyrimidine - 5 - Nucleotides G6PD deficiency - Heinz bodies Glutathione synthase - Antioxidant