This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Medicine
Treatment of 42 year old obese man with blood glucose 450 mg, urine albumin 2+ Sugar 4+ Ketone 1+ is - 
Select and explain. 
A. Insulin, B. Glibenclamide, C. Glipizide, D. Metformin
A: Insulin
Answer: A: Insulin 
Explanation: Answer is option 1 - insulin. Presence of sugar & ketone bodies in urine and hyperglycemia suggests diabetic ketoacidosis. Treatment of choice for diabetic ketoacidosis is insulin Ref Harrison 17 /p2073