This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Molecular Genetics, Subject name: Biochemistry
Unwinding Enzyme in DNA synthesis: 
Select and explain. 
A. Helicase, B. Primase, C. DNA Polymerase, D. Transcriptase
A: Helicase
Answer: A: Helicase 
Explanation: Ans. A. Helicase(Ref: Harper 31/e page 364)Classes of proteins involved in DNA replicationProteinFunctionDNA polymerasesDeoxynucleotide polymerizationHelicasesProcessive unwinding of DNATopoisomerasesRelieve torsional strain that results from helicase-induced unwindingProteinFunctionDNA primaseInitiates synthesis of RNA primersSingle-strand binding proteinsPrevent premature reannealing of dsDNADNA ligaseSeals the single strand nick between the Nascent chain and Okazaki fragments on lagging strand