This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of carbohydrate, Subject name: Biochemistry
Sandhoff's disease is d/t absence of which enzyme? 
Select and explain. 
A. Beta-hexosaminidase, B. Beta-glucuronibase, C. Aryl sulphatase, D. Alpha galactosidase
A: Beta-hexosaminidase
Answer: A: Beta-hexosaminidase 
Explanation: It is a lipid storage disease.Due to deficiency of hexaminidase.Leads to accumulation of globoside (Table;14.4)Ref: DM Vasudevan, 7th edition, page no: 193