This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Full form of LCAT is ? 
Select and explain. 
A. Lecithin cholesterol acyl transferase, B. Lecithin cholesterol alkyltransferase, C. Lecithin choline acetyltransferase, D. Lecithin choline alcohol transferase
A: Lecithin cholesterol acyl transferase
Answer: A: Lecithin cholesterol acyl transferase 
Explanation: Ans. is 'a' i.e., Lecithin cholesterol acyl transferase Lecithin-cholesterol acyl transferase (LCAT) is present in HDL and esterifies the cholesterol in HDL. Major activator of LCAT is Apo-Al. Apo-C1 can also activate LCAT.HDL-Cholesterol appears to be the best independent predictor of coronary aery disease (inverse relationship) than any other known risk factor. That means low HDL is a much stronger predictor of coronary aery disease than increased LDL cholesterol or increased total cholesterolThe intracellular cholesterol activates the intracellular enzyme acyl-CoA cholesterol acyl transferase (ACAT). This enzyme catalyzes transfer of an acyl group from a fatty acid derivative to cholesterol, resulting in the formation of esterified choleserol, and this cholesterol ester is stored for subsequent use.