This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Least common cause of endocarditis is: 
Select and explain. 
A. A.S.D, B. P.D.A, C. T.O.F., D. V.S.D.
A: A.S.D
Answer: A: A.S.D 
Explanation: Answer is A (ASD) Endocarditis is unusual in sites with a small pressure gradient as in ASD ASD is low risk lesion for the development of infective endocarditis and the single best answer amongst the options provided