This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
The genetic factors that can increase the susceptibility and modify the severity of pancreatic injury in acute pancreatitis are all, except: 
Select and explain. 
A. Cationic trypsinogen mutations, B. Pancreatic secretory trypsin inhibitor, C. CFTR, D. ATP7a gene mutation
D: ATP7a gene mutation
Answer: D: ATP7a gene mutation 
Explanation: There are some genetic factors that can increase the susceptibility and/or modify the severity of pancreatic injury in acute pancreatitis. They are, (1) Cationic trypsinogen mutations (2) Pancreatic secretory trypsin inhibitor (SPINK1) (3) CFTR, and (4) Monocyte chemotactic protein (MCP-1) Menkes syndrome is caused by mutations in the ATP7A gene. Reference: Harrisons Principles of Internal Medicine, 18th Edition, Page 2636