This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
T cell-dependent region is - 
Select and explain. 
A. Cortical follicles of lymph node, B. Medullary cords, C. Mantle layer, D. paracortical area
D: paracortical area
Answer: D: paracortical area 
Explanation: Periarterial lymphoid tissues

Thymus-dependent (T cells collection)

1. Spleen
    - Periarterial lymphoid collection
    - Malphigian corpuscle in the white pulp
2. Lymph node
           - Paracortical area

Thymus-independent (B cells collection)

1. Spleen
           - Perifollicular region
           - Mantel layer
2. Lymph node
           - Cortical follicles
           - Germinal centres
           - Medullary cords