This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Medicine
Most effective medication in GERD 
Select and explain. 
A. PPI, B. H, blockers, C. Antacids, D. Prokinetic drugs
A: PPI
Answer: A: PPI 
Explanation: (A) PPI > They self-medicate with over the counter medicines such as simple antacids, antacid-alginate preparations and H2recepto' antagonists.> PPis, such as Omeprazole, lansoprazole and pantoprazole, are by far the most effective drug treatment for GERD.