This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Basics of DNA, Subject name: Biochemistry
What is the approximate number of base pairs associated with a single nucleosome? 
Select and explain. 
A. 146, B. 292, C. 73, D. 1460
A: 146
Answer: A: 146 
Explanation: Nucleosomes Fundamental unit of DNA organisation. It is Histones complexed to DNA. Two molecules of each of H2A, H2B, H3,and H4 (Core histones) forms a histone octamer. 1 and 3/4 turns (~146 bp) DNA double helix is wound around the histone octamer in a left-handed fashion.