This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Skeletal system, Subject name: Radiology
Investigation of choice in whole body imaging in metastasis is - 
Select and explain. 
A. Magnetic Resonance Imaging, B. Radiography, C. Bone scan, D. CT Scan
C: Bone scan
Answer: C: Bone scan 
Explanation: Best investigation for bony metastasis is MRI. MRI has almost 100% sensitivity in detecting bony metastasis Investigation of choice for whole body screening for bony metastasis is Bone scan Intial investigation in symptomatic bone pain is Radiography CT is used in evaluation of focal abnormalities of bone scan and also for guided needle biopsy.