This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Psychiatry
A Bad prognostic indicator of Schizophrenia is - 
Select and explain. 
A. Late onset, B. Family history of Schizophrenia, C. Positive precipitating factors, D. Prominent affective symptoms
B: Family history of Schizophrenia
Answer: B: Family history of Schizophrenia 
Explanation: Poor prognostic factors:
Insidious onset, early onset (before 20 years of age); absence of precipitating stressor; poor premorbid adjustment; hebephrenic subtype (worst prognosis), simple, undifferentiated and chronic catatonic subtype; long duration (chronic course → >2 years); single / divorced; Negative symptoms; absence of depression; family history of schizophrenia; past history of schizophrenia; asthenic (thin) physique; male sex; poor treatment compliance & poor response to treatment; poor social support; flat or blunted affect; ventricular enlargement on brain CT scan; hospitalization & indoor treatment.