This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Acantholysis means - 
Select and explain. 
A. Diffuse epidermal hyperplasia, B. Loss of intercellular connections, C. Intercellular edema of the epidermis., D. Abnormal keratinization
B: Loss of intercellular connections
Answer: B: Loss of intercellular connections 
Explanation: Acantholysis : Loss of intercellular connections resulting in loss of cohesion between keratinocytes.