This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Reticulocytosis is NOT a feature of: 
Select and explain. 
A. Paroxysmal nocturnal hemoglobinuria, B. Following acute bleeding, C. Hereditary spherocytosis, D. Anemia in CRF
D: Anemia in CRF
Answer: D: Anemia in CRF 
Explanation: Answer is D (Anemia of chronic Renal Failure) Anemias of chronic renal failure and chronic disease are associated with low or normal reticulocyte counts. Elevated reticulocyle count is a feature of hyperproliferative anemias including PNH, hereditary spherocytosis and anemia after blood loss.