This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Central Nervous system, Subject name: Pharmacology
All of the following can be used to treat heroin dependence except 
Select and explain. 
A. Disulfiram, B. Buprenorphine, C. Clonidine, D. Lofexidine
A: Disulfiram
Answer: A: Disulfiram 
Explanation: Disulfiram is given for alcohol withdrawal. Buprenorphine is used as a maintaining drug in opioid addicts as it has a lesser degree of tolerance and dependence liability. Clonidine and lofexidine are alpha 2 agonists used to depress autonomic withdrawal symptoms like nausea, vomiting, anxiety and diarrhoea. Ref: KD Tripathi 8th ed.