This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Dental
Acantholysis is due to destruction of – 
Select and explain. 
A. Epidermis, B. Subepidermis, C. Basement membrane, D. Intercellular substance
D: Intercellular substance
Answer: D: Intercellular substance 
Explanation: Acantholysis occurs in → epidermis
Acantholysis is due to destruction of → Intercellular substance containg desmoglein.