This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Infection, Subject name: Medicine
Full blown immunodeficiency syndrome is characterized by - 
Select and explain. 
A. High viral titres with low CD4 count, B. Low viral titres with low CD4 count, C. High viral titres with high CD4 count, D. High CD4 and high CD8
A: High viral titres with low CD4 count
Answer: A: High viral titres with low CD4 count 
Explanation: Any HIV-infected individual with a CD4+ T cell count of <200/mL has AIDS by definition, regardless of the presence of symptoms or oppounistic diseases . (Harrison's Principles of internal medicine, 20 th edition, page 1506)