This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: FMGE 2018, Subject name: Microbiology
Which one of the following is a major component in activation of the complement alternative pathway: 
Select and explain. 
A. C1, B. C2, C. C3, D. C4
C: C3
Answer: C: C3 
Explanation: - Alternate complement pathway Activators factor- Cobra venom , Properidin ,nephritic - C3b , Bb - C3 convease of alternate complement pathway - C5 - C9 is MAC (membrane attack complex) - C1,4,2 are not consumed in the alternate complement pathway