This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
The following drugs are used for prophylaxis of migraine except 
Select and explain. 
A. Valproate, B. Topiramate, C. Meperidine, D. Metoprolol
C: Meperidine
Answer: C: Meperidine 
Explanation: Meperidine is opioid analgesic which is avoided in migraine.