This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: ENT
Topical Mitomycin C is useful in treatment of? 
Select and explain. 
A. Angiofibroma, B. Tracheal stenosis, C. Skull base Ostemyelitis, D. Laryngeal carcinoma
B: Tracheal stenosis
Answer: B: Tracheal stenosis 
Explanation: Laryngotracheal stenosis treated by serial dilatation using Jackson bronchoscopes. Laser have tendency to recur and hence adjuvant methods are done to decrease the rate of restenosis. Mitomycin C is an example of one of these adjunctive agents. It is a chemical derived from the Streptomyces caespitosus bacterium. It is an alkylating agent which has both antineoplastic and antiproliferative propeies and inhibits fibroblast production and thus prevents restenosis.