This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Antiplatelets and Fibrinolytics, Subject name: Pharmacology
Half life of alteplase is ? 
Select and explain. 
A. 5mins, B. 30mins, C. 1 hour, D. 2 hour
A: 5mins
Answer: A: 5mins 
Explanation: Ans. is 'a' i.e., 5 mins o Alteplase has a very short half-life (about 5 minutes) and, therefore, is administered as a total dose equal to 0.9mg kg.o Ten percent of the total dose injected intravenously as a bolus and the remaining drug is administered over 60 minutes.