This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Infection of Bones & Joints, Subject name: Orthopaedics
Which of the following is true regarding acute pyogenic osteomyelitis 
Select and explain. 
A. Most common site in bone is diaphysis of bone, B. Sequestrum is the new bone formation surrounding involucrum, C. Most common mode of infection is direct inoculation due to trauma, D. Cloacae are discharging sinuses.
D: Cloacae are discharging sinuses.
Answer: D: Cloacae are discharging sinuses. 
Explanation: Ans. D. Cloacae are discharging sinuses.a. Most common site of osteomyelitis is metaphysis.b. Sequestrum is dead piece of bone surrounded by involucrum (New bone).c. Most common mode of infection of bone is hematogenous.