This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
The bacterial resistance to tetracycline is due to: 
Select and explain. 
A. Alteration of drug binding sites, B. Alteration of dehydrofolate reductase, C. Inactivation of drug by enzymes, D. Decreased uptake of drug by bacteria
C: Inactivation of drug by enzymes
Answer: C: Inactivation of drug by enzymes 
Explanation: None