This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Most severe form of hereditary spherocytosis is caused by the mutation of - 
Select and explain. 
A. Ankyrin, B. Alpha spectrin, C. Beta spectrin, D. Band 3
B: Alpha spectrin
Answer: B: Alpha spectrin 
Explanation: . Alpha spectrin