This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Biochemistry
Coenzyme not required in formation of glutamate- 
Select and explain. 
A. Thiamine pyrophosphate, B. Pyridoxial phosphate, C. Niacin, D. None of the above
A: Thiamine pyrophosphate
Answer: A: Thiamine pyrophosphate 
Explanation: NAD+ is derived from nicotinic acid, a member of the vitamin B complex, used in the synthesis of GABA. During transamination reaction glutamate is formed. Pyridoxal Phosphate acts as a coenzyme. REF: Lippincott book of biochemistry 6th ed.