This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Breast, Subject name: Pathology
A 50-year-old woman has a lumpectomy following mammographic discovery of a carcinoma of the breast. Which of the following is a well-known characteristic or association of breast cancer? 
Select and explain. 
A. Low-fat diet, B. Positive family history, C. Excessive thinness, D. Multiparity
B: Positive family history
Answer: B: Positive family history 
Explanation: A history of breast cancer in first-degree female relatives and a diet high in animal fats are impoant associations of breast cancer. Associations related to excess estrogen stimulation include:- High-fat diet Obesity Early menarche Nulliparity. Additional associations are delayed first pregnancy and exogenous estrogen therapy.