This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hemolytic Anemias: Basic concepts and classification, Subject name: Pathology
Intrinsic causes of hemolytic anemia are all except: 
Select and explain. 
A. G6PD deficiency, B. Hereditary spherocytosis, C. Hypersplenism, D. Pyruvate kinase deficiency
C: Hypersplenism
Answer: C: Hypersplenism 
Explanation: - Hypersplenism is extracorpuscular cause of hemolytic anemia. - Causes of hemolytic anemias: INTRACORPUSCULAR CAUSES EXTRACORPUSCULAR CAUSES - Inherited causes: Hereditary spherocytosis G6PD deficiency; Pyruvate kinase deficiency Thalassemia Sickle cell anemia - Acquired causes: Paroxysmal Nocturnal Hemoglobinuria - Immune mechanism: ABO incompatibility Rh incompatability Autoimmune hemolytic anemia - Non immune mechanism: Clostridium toxin Snake venom Sequestration Mechanical damage - Angiopathic hemolytic anemia, march hemoglobinuria