This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidneys and Body Fluids, Subject name: Physiology
Thiazide diuretics act on: 
Select and explain. 
A. PCT mainly, B. DCT mainly, C. Loop of henle, D. All part of tubule
B: DCT mainly
Answer: B: DCT mainly 
Explanation: Ans. B DCT mainlyDiuretic classDrugsMOASite of actionOsmotic diureticMannitolInhibit water and solute reabsorptionAll part of tubule, but mainly proximal tubuleLoop diureticsFurosemide TorsemideInhibit Na+-K+-2Cl- transportThick ascending loop of henleThiazide diureticHydrochlorothi azide Benzthiazide Chlorthalidone IndapamideInhibit Na+-Cl- co-transportDistal tubuleK+ sparing diureticSpironolactoneTriamtereneAmilorideDecrease Na+ reabsorption Decrease K+ secretionCollecting tubuleCarbonic anhydrase inhibitorAcetazolamideInhibit H+ secretion and HCO3 reabsorption, whichreduces Na+ reabsorptionProximal tubule