This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
The coagulation profile in a 13-year old girl with Menorrhagia having Von Willebrands disease is: 
Select and explain. 
A. Isolated prolonged PTT with a normal PT, B. Isolated prolonged PT with a normal PTT, C. Prolongation of both PT and PTT, D. Prolongation of thrombin time
A: Isolated prolonged PTT with a normal PT
Answer: A: Isolated prolonged PTT with a normal PT 
Explanation: Answer is A (Isolated prolonged PTT with a normal PT) Von Willebrand disease is characterized by prolonged bleeding time and a prolonged PTT. The prothrombin time is normal.