This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General obstetrics, Subject name: Gynaecology & Obstetrics
In Down's syndrome, the serum markers.......... 
Select and explain. 
A. Increased MSAFP and UE3, Decreased PAPP-A and hCG, NT < 3mm, B. Decreased MSAFP, PAPP-A and UE3 and Increased hCG, NT > 3mm, C. Decreased MSAFP, PAPP-A , UE3 and hCG, NT > 3mm, D. Increased MSAFP, UE3, PAPP-A and hCG, NT < 3mm
B: Decreased MSAFP, PAPP-A and UE3 and Increased hCG, NT > 3mm
Answer: B: Decreased MSAFP, PAPP-A and UE3 and Increased hCG, NT > 3mm 
Explanation: Triple test (combined test): MSAFP, Unconjugated estriol (E3) and hCG. Quadruple test: MSAFP, UE3, hCG, Inhibit-A Integrated test: NT, PAPP-A + hCG reference: D C Dutta's Textbook of obstetrics 7th edition page no 494