This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Misc. (W.B.C), Subject name: Pathology
Triad of leukoerythroblastosis, tear drop erythrocytes and large platelets is seen in 
Select and explain. 
A. Essential thrombocytosis, B. Primary myelofibrosis, C. Myelodysplastic syndrome, D. Langerhan cell histiocytosis
B: Primary myelofibrosis
Answer: B: Primary myelofibrosis 
Explanation: Ans. (b) Primary myelofibrosis(Ref: Robbins 9th/pg 620/630)The most characteristic peripheral blood finding in PMF is myelophthisis, defined by the presence of leukoerythro- blastosis (presence of nucleated red blood cells, metamyelocytes, myelocytes, myeloblasts, and megakaryocytes) and dacryocytosis (Tear drop RBCs)