This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrine System, Subject name: Physiology
Panhypopituitarism in adults may lead to all of the following EXCEPT: 
Select and explain. 
A. Loss of secondary sexual characteristics, B. Pigmentation of skin, C. Intolerance to cold, D. Infeility
B: Pigmentation of skin
Answer: B: Pigmentation of skin 
Explanation: Panhypopituitarism in adult leads to: - Hypothyroidism - intolerance to cold Depressed production of glucocoicoids by adrenal glands. Loss of sexual functions, d/t suppressed secretions of the gonadotropic hormones Pigmentation is due to effect of MSH secreted by pituitary. In panhypopituitarism, levels of MSH decreases thus no pigmentation of skin