This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Other topics and Adverse effects, Subject name: Anatomy
Mrs Reeta Wardhan, a 50 year old female with rheumatoid ahritis is being considered for infliximab therapy. Which of the following test should be performed before beginning treatment 
Select and explain. 
A. Liver function test, B. PPD skin test, C. Pulmonary function test, D. Visual examination
B: PPD skin test
Answer: B: PPD skin test 
Explanation: Ref-Katzung 11/e p633 Infliximab is a monoclonal antibody against TNF-0. It is commonly used to treat moderate to severe rheumatoid ahritis paicularly in patients .adverse effects, including reactivation of latent tuberculosis. All patients being considered for TNF-a inhibitor therapy should have a baseline PPD skin test to screen for latent tuberculosis..