This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
Which of the following enzymes are responsible for generating 'oxygen burst' within neutrophils for killing intracellular bacteria? 
Select and explain. 
A. Superoxide dismutase, B. Glutathione peroxidase, C. NADPH Oxidase, D. Catalase
C: NADPH Oxidase
Answer: C: NADPH Oxidase 
Explanation: The final step in the microbial killing is due to reactive oxygen species called respiratory burst The generation of the oxygen metabolites is due to rapid activation of a leukocyte NADPH oxidase, called the phagocyte oxidase, which oxidizes NADPH and, in the process, conves oxygen to superoxide ion (O2 * ) The reactive oxygen species thus produced are toxic to bacteria and help the phagocyte kill them once they are ingested. ref robbins basic pathology 9th ed page 38