This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
Major neurotransmitter in afferents in nucleus tractus solitarius to regulate cardiovascular system ? 
Select and explain. 
A. Serotoxin, B. Glutamate, C. Glycine, D. Norepinephrine
B: Glutamate
Answer: B: Glutamate 
Explanation: Ans. is 'b' i.e., GlutamateNucleus tractus solitarius (NTS) lies in medulla.It receives following afferents :?A) General visceral afferentsi) From tonsil, pharynx, posterior pa of tongue, carotid body and sinus - through glossopharyngeal nerve.ii) From pharynx, larynx, trachea, esophagus, and other thoracic and abdominal viscera - through vagus nerve.B) Special visceral afferentsi) From anterior 2/3 of tongue (except circumvallate papillae) and palate - through facial nerveii) From posterior 1/3 of tongue (including circumvallate papillae) - through glossopharyngeal nerve.iii) From posterior most pa of tongue and epiglottis - through vagus nerve.NTS is involved in regulation of cardiovascular system through baroreceptors and chemoreceptors.There is a general consensus that glutamate is the neurotransmitter released at the therminals of baroreceptor and chemoreceptor afferents in NTS. -- <a href=" </a>However, cholinergic, GABAergic, and opioidergic mechanisms are also present in NTS.