This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Respiratory system, Subject name: Anatomy
Earliest lesion seen in asbestosis is: 
Select and explain. 
A. Pleural plaques, B. Hilar lymphadenopathy, C. Adenoma lung, D. Mesothelioma
A: Pleural plaques
Answer: A: Pleural plaques 
Explanation: It is the most common manifestation of asbestosis exposure composed of plaques of dense collagen containing calcium.they are usually asymptomatic and develop on anteroir and postereolateral pas of parietal pleura and over diaphragm.(ref Robbins 9/e p691)