This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Histo Pathology, Subject name: Pathology
Fixative used for bone histopathology is? 
Select and explain. 
A. 10% formalin, B. Normal saline, C. Rectified spirit, D. Nothing
A: 10% formalin
Answer: A: 10% formalin 
Explanation: ANSWER: (A) 10% formalinRE F: Atlas of mineralizedbone histology by HartmutH. Malluche, Marie-Claude Faugere, Hartmut H. Malluche page 26, Handbook of histology methods for bone and cartilage by Yuehuei H. An, Kylie L. Martin Page 159"10% natural buffered formalin (NBF) is the most commonly used fixative for bone specimens"Primary fixatives of bone tissue:1. 10% formalin2. Glutaraldehyde3. Paraformaldehyde4. Alcohol based solutionsSecondary fixatives of bone tissue:Zenkers solution (mercuric chloride, potassium dichromate, sodium sulfate, water, and acetic acid)Bouin's solution (picric acid, acetic acid and formaldehyde)