This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
HLA 2 is linked with - 
Select and explain. 
A. Graft rejection, B. Graft versus host disease, C. Killing of viral infected cells, D. Susceptibility to autoimmune diseases
B: Graft versus host disease
Answer: B: Graft versus host disease 
Explanation: Ans. is 'b' i.e., Graft versus host disease MHC class I is responsible for graft rejection and cell mediated cytolysis of viral infected or tumor cells.MHC-II is responsible for graft versus host response and mixed leukocyte reactionMHC-III is involved in susceptibility to autoimmune diseases like SLE.