This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Glycogen, Subject name: Biochemistry
A 3-month-old infant presents with hepatosplenomegaly and failure to thrive. A liver biopsy reveals glycogen with an abnormal, amylopectin like structure with long outer chains and missing branches. Which of the following enzymes would most likely be deficient: 
Select and explain. 
A. Alpha amylase, B. Branching enzyme, C. Debranching enzyme, D. Glucose-6-phosphatase
B: Branching enzyme
Answer: B: Branching enzyme 
Explanation: Disease is Anderson's disease/Amylopectinosis (GSD Type IV) Branching enzyme will be deficient Enzyme deficient Disease Features Branching enzyme Amylopectinosis Stored glycogen is abnormal long polysaccharide chains with few branch points resembles - Amylopectin Debranching enzyme Limit dextrinosis Limit dextrins (glycogen remains having shoer linear chains with very sho branch point)-accumulated Glucose-6-phosphatase Von-Gierke's disease Stored glycogen-Normal