This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pharmacology
If a diabetic patient being treated with an oral hypoglycemic agent develops dilutional Hyponatremia, which one of the following could be responsible for this effect 
Select and explain. 
A. Chlorpropamide, B. Tolbutamide, C. Glyburide, D. Glimepride
A: Chlorpropamide
Answer: A: Chlorpropamide 
Explanation: Refer KDT 6 /e p 267 Chlorpropamide is a first generation Sulfonylureas It increases the risk of hypoglycemia Other adverse effects of Chlorpropamide are ADH like action leading to dilutional Hyponatremia Cholestatic jaundice Disulfuram like reaction