This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cervical Carcinoma, Subject name: Gynaecology & Obstetrics
Most common serotype of HPV associated with cervical carcinoma is:- 
Select and explain. 
A. HPV 11, B. HPV 16, C. HPV 31, D. HPV 18
B: HPV 16
Answer: B: HPV 16 
Explanation: More than 90% of CIN is attributed to human papillomavirus (HPV) infection. Only ceain types of HPV cause high-grade intraepithelial lesions and cancer (HPV-16, -18, -31, -33, -35, -39, -45, -51, -52, -56, -58, -59, -68). Type 16 is the most common form of HPV found in invasive cancer and in CIN 2 and CIN3; HPV-18 is more specific than HPV-16 for invasive tumors i.e. HPV 18 is the most malignant. Please note: Usually, HPV infections do not persist. Most women who are exposed have no clinical evidence of disease, and the infection is eventually suppressed or eliminated. Other women exhibit low-grade cervical lesions that mostly regress spontaneously. In the vast majority of cases, the infection will clear in 9 to 15 months. A small minority of women exposed to HPV develops persistent infection that may progress to CIN.