This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hormones, Subject name: Physiology
Following is true of hormone leptin except: 
Select and explain. 
A. It is found in increased levels in obese, B. Site of action is hypothalamus, C. It is produced by adipose all, D. It increases appetite
D: It increases appetite
Answer: D: It increases appetite 
Explanation: Ans: D (It increases appetite) Ref: Pal GK, Functions of Hypothalamus, In: Textbook of Medical Physiology, Ahuja Publishing House, 118:889Explanation:LeptinProtein of 167 amino acidsManufactured primarily in the adipocytesHigh leptin level occurs in obesity - | sympathetic activity; | food intakeLow- leptin level occurs in starvation | parasympathetic activity; | food intakeActs on hypothalamus, arcuate nucleus identifies plasma leptin concentration.Regulates onset of pubertyStimulates thyroid functionControls glucocorticoid secretion