This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Other topics and Adverse effects, Subject name: Anatomy
Metabolism of a drug primarily results in 
Select and explain. 
A. Activation of the active drug, B. Conversion of prodruv to active metabolite, C. Conversion of lipid soluble drugs to water soluble metabolites, D. Conversion of water soluble drugs to lipid solible metabolites
C: Conversion of lipid soluble drugs to water soluble metabolites
Answer: C: Conversion of lipid soluble drugs to water soluble metabolites 
Explanation: Ref-Katzung 10/e p50 After metabolism most of the drugs become inactive and their excreted through the kidney. Lipids soluble drugs wil be reabsprbed whereas water soluble drugs are easily excreted.thus, metabolism of drugs helps in the conversion of liquid soluble drugs to water soluble metabolites