This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hypertension, Subject name: Medicine
Resistant hypertension is defined as? 
Select and explain. 
A. Resistance to 3 or more anti hypertension drugs, B. Resistance to 3 or more anti-hypertensive drugs including thiazides, C. Resistance to aldosterone, D. Resistance of Angiotension II receptors
B: Resistance to 3 or more anti-hypertensive drugs including thiazides
Answer: B: Resistance to 3 or more anti-hypertensive drugs including thiazides 
Explanation: Ans. (b) Resistance to 3 or more anti-hypertensive drugs including thiazidesRef: Harrison 18th edition, chapter 247* Resistant hypertension refers to patients with blood pressures persistently >140/90 mmHg despite taking three or more antihypertensive agents, including a diuretic, in a reasonable combination and at full doses.* Resistant or difficult-to-control hypertension is more common in patients >60 years than in younger patients.* Resistant hypertension may be related to:# "Pseudoresistance" (high office blood pressures and lower home blood pressures), nonadherence to therapy# Identifiable causes of hypertension (including obesity and excessive alcohol intake# Use of any of a number of nonprescription and prescription drugs