This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Misc. (R.B.C), Subject name: Pathology
5-year old male child presented to AIIMS pediatrics OPD with severe transfusion requiring anemia and Jaundice. On examination Liver and spleen were palpable 5 cm below the costal margin. Peripheral smear analysis showed the following? What is your diagnosis? 
Select and explain. 
A. Nutritional anemia, B. Aplastic anemia, C. Autoimmune hemolytic anemia, D. Thalassemia
D: Thalassemia
Answer: D: Thalassemia 
Explanation: Ans. (d) ThalassemiaSevere transfusion requiring anemia and Jaundice with smear showing Anisopoikilocytosis and targets on smear suggests Thalassemia.