This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cholera, Subject name: Social & Preventive Medicine
In cholera epidemic which step should be first taken: 
Select and explain. 
A. Vaccination to all individuals immediately, B. Primary chemoprophylaxis, C. Cure with tetracycline, D. Safe water supply and sanitation
D: Safe water supply and sanitation
Answer: D: Safe water supply and sanitation 
Explanation: Ans. (d) Safe water supply and sanitationRef K. Park 23rded. /232-33* Cholera is an acute diarrheal disease caused by Vibrio cholerae.* I.P.-1-2 days* First step in epidemic of cholera: Verification of diagnosis* First line treatment of choice: water and electrolyte replacement.* In the given question, safe water supply and sanitation should be the 1st step to decrease mortality from cholera.Also know* Stool appearance of cholera: "Rice watery stool* Chemoprophylaxis of cholera: Tetracycline 500mg BID for 5 days.* Drug of choice for cholera:# Adults: Doxycycline 300 mg stat.# Children: Cotrimoxazole 5mg/kg BID for 3 days# Pregnant female: Furazolidone 100mg QID for 3 days.