This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: ENT
Treatment of leukoplakia - 
Select and explain. 
A. Local excision, B. Excision and radiotherapy, C. Topical chemotherapy, D. Repositioning of ill fitting dentures
D: Repositioning of ill fitting dentures
Answer: D: Repositioning of ill fitting dentures 
Explanation: Treatment of oral leukoplakia 

Usually, all that is needed for the treatment of oral leukoplakia is just to remove the source of the irritation. If leukoplakia is caused by a rough edge of a tooth, filling or crown or by a denture that does not fit properly, the surface should be smoothed and the dental appliances repaired.
For most people, changing life habits by stopping smoking or alcohol consumption clears the condition in a few weeks or months.
If removing the irritating factor is not effective in clearing the patches, leukoplakia treatment may include surgical removal (excision) or ablation with laser or cryotherapy.
A biopsy should be conducted to rule out malignancy.