This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
The expression of the following oncogene is associated with a high incidence of Medullary carcinoma of thyroid- 
Select and explain. 
A. P 53, B. Her 2 neu, C. RET protooncogene, D. Rb gene
C: RET protooncogene
Answer: C: RET protooncogene 
Explanation: Harshmohan textbook of pathology 7th edition. RET gene is a proto oncogene normally code for receptor for growth factor ( RET receptor). Point mutation to this gene causes multiple endocrine neoplasi type 2A, type2B , medullary carcinoma of thyroid..