This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Physiology
True about leukemia in Down's syndrome is 
Select and explain. 
A. Acute leukemia less common than gen population, B. AML more common than ALL, C. Prog in AML is better than gen population, D. If diagnosed with ALL, should be given higher doses of methotrexate
C: Prog in AML is better than gen population
Answer: C: Prog in AML is better than gen population 
Explanation: In this group of patients, the repoed event-free survival rates have ranged from 80 to 100%. On the other hand, the outcome of Down syndrome children with acute lymphoblasticleukemia (ALL) has been historically considered worse than the outcome of ALL patients withoutDown syndrom Ref ganong's review of medical physiology 25e