This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
Regarding alpha feto-protein true statement . 
Select and explain. 
A. Major source in fetal life is yolk sac, B. Commonly incrased in wilms tumour, C. Maximum level at 20th week, D. Half life 5-7 days
A: Major source in fetal life is yolk sac
Answer: A: Major source in fetal life is yolk sac 
Explanation: Ans. is a i.e. Major source in fetal life is yolk sac As discussed earlier : "AFP is synthesized early in gestation by the fetal yolk sac and later by the fetal GlTand liver." No where it is given that major source is yolk sac so this statement (option "a") is paially correct. AFP levies are not increased in wilms tumour (i.e. option "b- is incorrect). Maximum level of AFP in : Fetal serum is at - 13 weeks Amniotic fluid is at 13 weeks. - Maternal serum is at 28-32 weeks. So, option 'c' is incorrect. Half life of AFP is 3.5 days (Internet) so, option 'd' is wrong. Amongst all the options given - Option 'a is the best bet.