This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pharmacology
Lipid lowering drug that significantly reduces lipo protein-a levels is? 
Select and explain. 
A. Fenofibrate, B. Gemfibrosil, C. Rosuvastatin, D. Nicotinic acid
D: Nicotinic acid
Answer: D: Nicotinic acid 
Explanation: Nicotinic acid is B3 vitamin which in higher doses reduce plasma lipids. When nicotinic acid is given, TGs and VLDL decrease rapidly, followed by a moderate fall in LDH-CH and total CH. It also reduces Lp(a) which is considered more atherogenic. It acts by inhibiting lipoprotein lipase produced from the endothelium From essentials of medical pharmacology K D Tripathi 7th edition page no 640