This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
Curshmann's crystals are seen in - 
Select and explain. 
A. Bronchial asthma, B. Bronchiectasis, C. Chronic bronchitis, D. Wegners granulomatosis
A: Bronchial asthma
Answer: A: Bronchial asthma 
Explanation: Ans. is 'a' i.e., Bronchial asthma Pathology of AsthmaGross -o Lungs are overdistended because of overinflation and there may be small area of atelactasis.o The most striking macroscopic finding is occlusion of bronchi and bronchioles by thick tenacious mucus plugs.Histology -o Characterized by presence of numerous eosinophils and neutrophils.Curschman spiral - Whorls of shed epithelium in mucus plugs.Charcot -leyden crystals - Collection of crystalloids made up of eosinophilic membrane protein.The other characteristic histological finding of Asthma is collectively called Airway remodelling, it includes -o Thickening of the basement membrane of the bronchial epithelium.o Edema and an inflammatory infiltrate in the bronchial walls with a prominence of eosinophils and mast cells,o An increase in the size of submucosal glands,o Hypertrophy of bronchial wall muscle.The "airway remodelling" contributes to airflow obstruction.