This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
Which of the following statement regarding Wiskott aldrich syndrome is TRUE? 
Select and explain. 
A. Primary defect is B cell defect, B. Primary defect is T cell defect, C. Associated with WASP gene mutation, D. Defect in phagocytosis
C: Associated with WASP gene mutation
Answer: C: Associated with WASP gene mutation 
Explanation: Wiskott Aldrich syndrome is caused by mutation in the WASP gene which produces a protein Wiskott Aldrich syndrome protein. WASP gene is located on the sho arm of X chromosome. It is an X linked immunodeficiency disorder Cardinal features are: Thrombocytopenia Recurrent pyogenic and oppounistic infections staing from 6 months of age Eczema of varying degrees staing at about 1 year of age Normal serum levels of IgA and IgE, slightly increased IgG and decreased amount of IgM. Defective T cell function Normal B cell function