This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
The finnish type of congenital nephritic syndrome occurs due to gene mutation affecting the following protein - 
Select and explain. 
A. Podocin, B. Alpha-actinin, C. Nephrin, D. CD2 activated protein
C: Nephrin
Answer: C: Nephrin 
Explanation: Ans. is 'c' i.e., Nephrin Congenital nephrotic syndrome o Infant who develop nephrotic syndrome within the first 3 months of life are considered to have congenital nephrotic syndrome. o The most common cause of this syndrome is finnish-type congenital nephrotic syndrome, an autosomal recessive disorder. o Two most common genes involved are - i) NPHS1--> Coding for nephrin and results in finnish-type nephrotic syndrome. ii) NPHS2 --> Coding for Podocin and results in FSGS.