This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Galactose and fructose metabolism, Subject name: Biochemistry
Warburg effect is: 
Select and explain. 
A. Aerobic glycolysis, B. Anaerobic glycolysis, C. Inhibition of glycolysis by oxygen, D. Inhibition of oxygen uptake by glycolysis
A: Aerobic glycolysis
Answer: A: Aerobic glycolysis 
Explanation: Warburg effect is aerobic glycolysis. Warburg effect Cancer cells conve pyruvate to lactate even in the presence of O2. This is known as aerobic glycolysis. Lactic acid produces local acidic environment helping in metastasis. Energy is derived from conversion of pyruvate to lactate is just 2 ATPs, cancer cells take up large amount of glucose compared to normal cells. This enhanced glucose uptake is the biochemical basis of PET scan.