This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Anaesthesia
Intravenous regional anaesthesia is contraindicated in 
Select and explain. 
A. Sickle cell disease, B. Thalassemia, C. Hereditary spherocytosis, D. G6PD deficiency
A: Sickle cell disease
Answer: A: Sickle cell disease 
Explanation: As tourniquet application can precipitate sickling and hypoxia, IVRA is contraindicated in sickle cell anemia.