This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: ENT
Which of the following conditions is associated with maximum hearing loss? 
Select and explain. 
A. Otitis media with effusion, B. Paial fixation of the stapes footplate, C. Ossicular disruption with intact tympanic membrane, D. Disruption of malleus and incus as well tympanic membrane
C: Ossicular disruption with intact tympanic membrane
Answer: C: Ossicular disruption with intact tympanic membrane 
Explanation: Maximum hearing loss occur when there is ossicular interruption with intact tympanic membrane (54dB). Ossicular interruption with perforation result in 38dB hearing loss, hearing loss in ottitis media with effusion averages about 26-30 dB. Paial or complete fixation of the stapes results in conductive hearing loss that ranges from 5dB to 60dB.