This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Central Nervous system, Subject name: Pharmacology
The effect of thiopentone on the CNS is quickly terminated because of: 
Select and explain. 
A. Rapid metabolism in the CNS, B. Quick first-pass elimination, C. Redistribution, D. Rapid metabolism in systemic circulation
C: Redistribution
Answer: C: Redistribution 
Explanation: Thiopentone is a ultra sho acting barbiturates ,its action is terminated because of redistribution . thiopentone is highly lipid soluble ,after i.v injection consciousness is regained in 6-10 minutes due to redistribution ,while the ultimate disposal occurs by metabolism. Greater the lipid solubility of the drug ,faster is its redistribution. Ref: KD Tripathi 8th ed