This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of carbohydrate, Subject name: Biochemistry
Coris disease is due to defect in 
Select and explain. 
A. Branching enzyme, B. Debranching enzyme, C. Myophosphorylase, D. Hepatic phosphorylase
B: Debranching enzyme
Answer: B: Debranching enzyme 
Explanation: It is type III glycogen storage disease. to deficiency of the debranching enzyme. Clinical features: highly branched dextrin accumulate, fasting hypoglycemia, hepatomegaly.Ref: DM Vasudevan, 7th edition, page no: 125