This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hepatic encephalopathy & hepatic failure, Subject name: Medicine
Most specific indicator of liver injury? 
Select and explain. 
A. ALT, B. AST, C. SAP, D. 5' nucleotidase
A: ALT
Answer: A: ALT 
Explanation: Most specific indicator of liver injury is: ALT: SGPT (product present in cytosol that come in blood due to injury) AST: SGOT, present in cardiac tissue/liver so it's not specific SAP: (Cholestasis marker) Do not indicate hepatocyte necrosis 5' nucleotidase: Cholestasis marker