This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology and breast, Subject name: Surgery
In which of the following types of breast carcinoma, would you consider biopsy of opposite breast 
Select and explain. 
A. Adenocarcinoma-poorly differentiated, B. Medullary carcinoma, C. Lobular carcinoma, D. Comedo carcinoma
C: Lobular carcinoma
Answer: C: Lobular carcinoma 
Explanation: In lobular carcinoma because: High chance to predispose to invasive carcinoma. 35% of lobular carcinoma in situ may devolop invasive lobular carcinoma either in the same or contralateral breast, 65% may devolop invasive ductal carcinoma. It is multifocal, bilateral(50%). So biopsy from opposite breast should be taken. Reference: SRB's Manual of Surgery, 6th Edition, page no = 526.