This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Which of the following immunosuppressant drugs is nephrotoxic? 
Select and explain. 
A. Azathioprine, B. Cyclophosphamide, C. Mycophenolate mofetil, D. Tacrolimus
D: Tacrolimus
Answer: D: Tacrolimus 
Explanation: Tacrolimus and cyclosporine toxicity include nephrotoxicity, neurotoxicity, hyperglycemia, hypertension, hyper­kalemia and GI complaints. Cyclosporine also cause hirsutism, which is not seen with tacrolimus use.