This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Growth and development, Subject name: Pediatrics
The Simian crease is not seen in ______ 
Select and explain. 
A. Down syndrome, B. Trisomy 13, C. Cri du chat syndrome, D. Cystic Fibrosis
D: Cystic Fibrosis
Answer: D: Cystic Fibrosis 
Explanation: Simian crease (single transverse palmar crease) is not seen in cystic fibrosis. Simian crease is seen in : Down&;s syndrome Fetal alcohol sydrome Trisomy 13 Cri du chat syndrome Ref: Online resources