This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Musculoskeletal system, Subject name: Pathology
a-synuclein, a lipid-binding protein, is a major component of 
Select and explain. 
A. Lewy bodies, B. Amyloid, C. Tau protein, D. Neurofibrillary tangles
A: Lewy bodies
Answer: A: Lewy bodies 
Explanation: a-synuclein, an abundant lipid-binding protein normally associated with synapses. This protein was then demonstrated to be a major component of the Lewy body, which is the diagnostic hallmark of Parkinson diseaseRobbins pathology9e pg: 1294