This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General physiology, Subject name: Physiology
Most abundant extracellular buffer is 
Select and explain. 
A. Haemoglobin, B. Plasma proteins, C. Bicarbonate, D. Phosphate
C: Bicarbonate
Answer: C: Bicarbonate 
Explanation: Bicarbonate buffer is rhe major buffer system in the body It is responsible for about 80%of extra cellular buffering Ref:Guyton and Hall textbook of medical physiology 12th edition,page number:489,490,491