This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Pathology
Most common cytogenetic abnormality in Multiple myeloma is 
Select and explain. 
A. Deletion 13q, B. T, C. T, D. T
A: Deletion 13q
Answer: A: Deletion 13q 
Explanation: Multiple myeloma/solitary plasmacytoma: Genotype: Diverse rearrangements involving IgH; 13q deletionsSalient Features: older adults with lytic bone lesions, pathologic fractures, hypercalcemia, and renal failure; moderately aggressive Plasmacytoma: isolated plasma cell masses in bone or soft tissue; indolent Reference: Robbins and Cotran Pathologic Basis of Disease; 9th edition; Chapter 13; Disorders of white cells