This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Physiology
Alpha-methyldopa is primarily used for 
Select and explain. 
A. Pregnancy induced hypeension, B. Renovascular hypeension, C. First line agent in hypeension, D. Refractory hypeension
A: Pregnancy induced hypeension
Answer: A: Pregnancy induced hypeension 
Explanation: They act on central alpha 2a receptors to decrease efferent sympathetic activity. It decreases t.p.r more than H.R or C.O It is infrequently used now. (Ref: Essentials of medical pharmacology, K.D Tripathi, 7th edition, page 566)