This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Demyelinating disorder, Subject name: Medicine
Which of the following is used in acute exacerbation of multiple sclerosis? 
Select and explain. 
A. Methylprednisolone, B. Fingolimod, C. Beta interferon, D. Natalizumab
A: Methylprednisolone
Answer: A: Methylprednisolone 
Explanation: For acute attack of M.S = IV methyl prednisolone Glucocoicoids are used to manage first attacks or acute exacerbations of multiple sclerosis, usually present as optic neuritis.