This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Schizophrenia and other psychotic disorders, Subject name: Psychiatry
Intense depression & misery without any cause is 
Select and explain. 
A. Melancholia, B. Mania, C. Schizophrenia, D. Major depressive disorder
A: Melancholia
Answer: A: Melancholia 
Explanation: Melancholia:- Melancholia is severe depressive state with psychomotor retardation. Ref:- Kaplan & Sadock's Synopsis of Psychiatry 10th edition; Pg num:- 1892