This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Management of steroid resistant asthma is done by: March 2005 
Select and explain. 
A. Oral steroids, B. Long acting Beta-2 agonist, C. Leucotrine antagonist, D. Theophylline
A: Oral steroids
Answer: A: Oral steroids 
Explanation: Ans. A: Oral steroids It is defined as failure to respond to a high dose of oral prednisolone (40 mg once daily over 2 weeks) More common is reduced responsiveness to coicosteroids where control of asthma requires oral coicosteroids (coicosteroid dependent asthma) Most of these patients requires a maintenance therapy with oral coicosteroids. Low dose of theophylline may be helpful in some patients. Few patients may benefit from infusion of beta-2 agonists.