This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
Neural tube defect is due to deficiency of: March 2012 
Select and explain. 
A. Vitamin B12, B. Thiamine, C. Folic acid, D. Riboflavin
C: Folic acid
Answer: C: Folic acid 
Explanation: Ans: C i.e. Folic acid Folic acid supplementation beginning 1 month before conception to about 12 weeks of pregnancy has reduced the incidence of neural tube defects significantly (85%).