This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Runt's disease is associated with 
Select and explain. 
A. Acute rejection, B. Hyperacute rejection, C. GVHD, D. Chronic rejection
C: GVHD
Answer: C: GVHD 
Explanation: GVHD Robbins, 7 edition, Page 222 * Runt's disease: is a pathological condition in which cells from the transplanted tissue of a donor initiate an immunologic attack on the cells and tissue of the recipient Complications of small bowel transplantation: * Most of the moality after bowel transplantation is due to sepsis and multiorgan failure. * The risk of infection after small bowel transplantation is heightened by the additional requirements for immunosuppression in order to control graft rejection. * This accounts for the relatively high incidence of Lymphoproliferative disease (around 10%) observed in patients who have undergone small bowel transplantation. * Because of the large amount of donor lymphoid tissue transplanted Graft- Versus-Host Disease (GVHD) may occasionally be an added complication