This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
True about sitagliptin is all except 
Select and explain. 
A. Used in type II DM, B. Used in combination with other oral hypoglycaemic, C. Cannot be used orally, D. All are true
C: Cannot be used orally
Answer: C: Cannot be used orally 
Explanation: Ans. is 'c' i.e., Cannot be used orally Sitagliptin This is orally active inhibitor of DPP-4. It prevents degradation of endogenous GLP- 1 and other incretins, potentiating their action, resulting in limitation of postprandial hyperglycemia. It is used in type 2 DM. Other DPP-4 inhibitor is vildagliptin.