This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pharmacology
True statement is - 
Select and explain. 
A. Clomiphene acts as antiestrogen both on pitatary and hypothalamus, B. Danazol increases FSH and LH both, C. Methimazole inhibits thyroxine release from thyroid, D. Cyproterone is a potent antiandrogen
D: Cyproterone is a potent antiandrogen
Answer: D: Cyproterone is a potent antiandrogen 
Explanation: Ans. is 'd' Cyproterone acetate in a potent antiandrogen Reference see below.Clomiphene citrate is an antiestrogen It induces gonadotropin secretion in women by blocking estrogenic feed back inhibition of pituitary . It has no effect on hypothalamus Danazol - It has mild androgenic, anabolic and progestational activity. However the most prominent action is suppression of Gonadotropin secretion i.e. FSH and LH secretion Cyproterone acetate - It is a potent anti-androgen. It compete with dihydrotestosterone for the intracellular androgen receptor and inhibits its binding.Methimazole - Methimazole is an antithyroid drug which prevents the synthesis of thyroid hormones*