This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Infection, Subject name: Pediatrics
Pertussis vaccine side effect - 
Select and explain. 
A. Local pain, B. Excessive cry, C. Fever, D. All of above
D: All of above
Answer: D: All of above 
Explanation: Ans. is 'd' i.e., All of the above o Pertussis vaccineAvailable as whole cell and acellular as DTPw and DTPaPrimary immunisation at 6, 10, 14 weeks followed by booster dose IVi year and 5 year.Whole cell causes more side effect than acellular.Side effect-local pain, redness, fever, irritability, excessive cry because of cortical irritation.ContraindicationProgressive neurological disease (Relative)Immediate anaphylasixEncephalopathyPersistent Inconsable cryHypotensive - hyporesponsive episode