This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
Which of the following is true of fat embolism - 
Select and explain. 
A. Thrombocytopenia, B. Macroglobulinemia, C. Prothrombin time increased, D. Fat globules in urine
A: Thrombocytopenia
Answer: A: Thrombocytopenia 
Explanation: symptomatic fat embolism syndrome characterized by pulmonary insufficiency, neurologic symptoms, anemia, thrombocytopenia, and a diffuse petechial rash, which is fatal in 10% of cases. Clinical signs and symptoms appear 1 to 3 days after injury as the sudden onset of tachypnea, dyspnea, tachycardia, irritability, and restlessness, which can progress rapidly to delirium or coma ( Robbins Basic Pathology, 9 th edition, page 91 )