This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology and breast, Subject name: Surgery
Treatment of choice in Medullary Ca thyroid 
Select and explain. 
A. Total thyroidectomy, B. Total thyroidectomy + Radical neck dissection, C. Total thyroidectomy + Radiotherapy, D. Total thyroidectomy + Prophylactic CCND
D: Total thyroidectomy + Prophylactic CCND
Answer: D: Total thyroidectomy + Prophylactic CCND 
Explanation: Surgery is the main therapeutic modality. Total thyroidectomy with bilateral central node dissection and ipsilateral lateral neck dissection if primary tumor is greater than 1cm or central nodes are positive. Reference: SRB's Manual of Surgery, 6th Edition, page no= 477. Reference: Bailey & love, 26th Edition, page no =769.