This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Wilson's disease is characterized by ? 
Select and explain. 
A. Increased serum ceruloplasmin, B. Decreased copper excretion in urine, C. Increased copper in liver, D. Autosomal dominant
C: Increased copper in liver
Answer: C: Increased copper in liver 
Explanation: Ans. is 'c' i.e., Increased copper in liver Diagnosis of Wilson disease The gold standard for diagnosis is liver biopsy with quantitative copper assay - concentration of copper in a liver biopsy sample > 200 mg/g dry weight. Other tests are ? Serum ceruloplasmin level - low Urine copper excretion - increased KF rings DNA Haplotype analysis.