This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Sickle Cell anaemia all are true except 
Select and explain. 
A. The shift from HbF to HbS occurs due to point mutation., B. Microvascular occlusion is a severe complication of SCA, C. Deoxygenation of RBC can lead to extensive membrane damage, D. Adults but not children; with  sickle  cell  disease  are  functionally  asplenic,  making them  susceptible  to  infections  caused  by  encapsulated  bacteria,  such  as  pneumococci.
D: Adults but not children; with  sickle  cell  disease  are  functionally  asplenic,  making them  susceptible  to  infections  caused  by  encapsulated  bacteria,  such  as  pneumococci.
Answer: D: Adults but not children; with  sickle  cell  disease  are  functionally  asplenic,  making them  susceptible  to  infections  caused  by  encapsulated  bacteria,  such  as  pneumococci. 
Explanation: None