This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General obstetrics, Subject name: Gynaecology & Obstetrics
Increased levels of which of the following in amniotic fluid is an indicator of neural tube defect in the fetus : 
Select and explain. 
A. Acetylcholinesterase, B. Butyrylcholinesterase, C. Pseudocholinesterase, D. Phosphatidyl esterase
A: Acetylcholinesterase
Answer: A: Acetylcholinesterase 
Explanation: Acetylcholine esterase: (AChE) Amniotic fluid AChE level is elevated in most cases of open neural tube defects. It has got better diagnostic value than AFP. Reference: D C Dutta's Textbook of Obstetrics 7th edition page no 113