This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Surgery
Which is not true about PBC? 
Select and explain. 
A. No increase in risk of hepatocellular carcinoma, B. Often asymptomatic, C. Elevated 1gM, D. Positive antimitochondrial antibody
A: No increase in risk of hepatocellular carcinoma
Answer: A: No increase in risk of hepatocellular carcinoma 
Explanation: .PBC(primary biliary cirrhosis) is a chronic & slowly progressive cholestatic disease of autoimmune etiology characterised by injury of the intrahepatic bile ducts that may eventually lead to liver failure.The risk for HCC is increased in PBC.So screening for it can be done by ultrasound scan every 6 months. Most of the patients with PBC(>90%) have antimitochondrial Ig M antibodies against pyruvate dehydrogenase complex(PDC-E2).