This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Medicine
Hypeension with Hypokalemia is seen in: 
Select and explain. 
A. Bater Syndrome, B. Liddle's Syndrome, C. Gitelman's Syndrome, D. All of the above
B: Liddle's Syndrome
Answer: B: Liddle's Syndrome 
Explanation: Liddle&;s Syndrome is typically associated with Hypokalemia and Hypeension. Rater&;s Syndrome and Gitelman&;s Syndrome are also associated with hypokalemia but without hypeension. Liddle&;s Syndrome : Review Pathophysiology: * Autosomal dominant disorder. * Genetic defect in the collecting tubule sodium channel, resulting in increased sodium reabsorption and lack of inhibition by higher levels of intracellular sodium Age of Presentation * Often diagnosed at young age, but can present in adulthood due to phenotypic variation. Clinical presentation * Classic triad of hypeension, metabolic alkalosis, and hypokalemia. * Consider iffamily history of hypeension and/or hypokalemia. at young age Lab data * Metabolic alkalosis, hrpokalemia (although some are low normal), low urinary aldosterone secretion Treatment: * Lifelong. Potassium-sparing diuretic which closes the sodium channel (Amiloride or Triamterene). Spironolactone does not work.