This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunology, Subject name: Microbiology
The prototype of type-II hypersensitivity reaction is - 
Select and explain. 
A. Ahus reaction, B. SLE, C. Autoimmune hemolytic anemia, D. Contact dermatitis
C: Autoimmune hemolytic anemia
Answer: C: Autoimmune hemolytic anemia 
Explanation: Type II hypersensitivity reaction is initiated by IgG or rarely IgM antibodies that react either with cell surface or tissue antigen. Cell or tissue damage occurs in the presence of complement or mononuclear cells. - Example is lysis of red cells caused by anti-erythrocyte antibodies in autoimmune hemolytic anemia. Reference : Anathanarayan & paniker's 9th edition, pg no: 166,162 <\p>