This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Breast, Subject name: Pathology
Which is rheumatic ahritis autoantibody - 
Select and explain. 
A. Anti DLE, B. Anti CCP, C. Anti ds DNA, D. Anti histone
B: Anti CCP
Answer: B: Anti CCP 
Explanation: Answer is anti ccp Rheumatoid ahritis is an autoimmune disease involving complex and still poorly understood interactions of genetic risk factors, environment and the immune system. In atleast 70% of patients the blood contains anti-ccp antibody, which may be produced during inflammation. These antibodies contribute to the bone lesions. Robbins basic pathology 9th edition page no 784,heading box=Pathogenesis