This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Specific Cytogenetic Disorders, Subject name: Pathology
Syndrome which is associated with increased risk of leukaemia: 
Select and explain. 
A. Plummer Vinson syndrome, B. Klienfelter syndrome, C. Sturge webber syndrome, D. Multiple Hamaoma
B: Klienfelter syndrome
Answer: B: Klienfelter syndrome 
Explanation: Association of Klinefelter syndrome Breast cancer Extragonadal germ cell tumors Autoimmune diseases (SLE) Acute leukaemia.