This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Type4 Ehlers-Danlos syndrome is characterized by: 
Select and explain. 
A. Deficiencies in hydroxylase and lysyl oxidase., B. Decreased amount of type III collagen., C. Nonfunctioning plasma fibronectin., D. All of the above.
B: Decreased amount of type III collagen.
Answer: B: Decreased amount of type III collagen. 
Explanation: In EDS types I and II, the classic variety, causative mutations may involve the COL5A1, COL5A2, and tenascin-X genes. Type IV is characterized by a decreased amount of type III collagen. Types V and VI are characterized by deficiencies in hydroxylase and lysyl oxidase, an important posttranslational modifying enzyme in collagen biosynthesis. Type VII has an amino-terminal procollagen peptidase deficiency. Type IX has abnormal copper metabolism. Type X has nonfunctioning plasma fibronectin.