This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Central Nervous system, Subject name: Pharmacology
All of the following statements about trientine use in Wilson's disease are true except: 
Select and explain. 
A. It is more potent than penicillamine., B. It is used as an alternative to penicillamine in non-tolerant patients, C. It should not be administered with in two hours of iron supplementation, D. It can cause iron def anemia which is reversible by oral iron supplements
A: It is more potent than penicillamine.
Answer: A: It is more potent than penicillamine. 
Explanation: *Penicillamine is the most potent chelating agent useful in Wilson's disease. *Trientine is not as potent as penicillamine and was used in patients unable to tolerate penicillamine.However,now a days, trientine is preferred because of severe adverse effects of penicillamine. *Trientine cause fewer adverse effects other than mild anemia due to iron deficiency in few patients. Ref: KATZUNG 14TH ED.