This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Which of the following chemotherapeutic agents is associated with secondary leukemia 
Select and explain. 
A. Vinblastine, B. Paclitaxel, C. Cisplatin, D. Bleomycin
C: Cisplatin
Answer: C: Cisplatin 
Explanation: Alkylating agents bind to DNA and has the potential to introduce mutations. Therefore, these agents can cause sec­ondary leukemias. Procarbazine is most important drug implicated in causation of secondary leukemias.
Cisplatin acts by similar mechanism and can cause leukemia.