This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Childhood tumors, Subject name: Pediatrics
True about neuroblastoma 
Select and explain. 
A. Tumor of automatic nervous system, B. Metastasis rarely present, C. Earliest detected in late childhood, D. Most common site is Adrenal medulla
A: Tumor of automatic nervous system
Answer: A: Tumor of automatic nervous system 
Explanation: Neuroblastoma is a malignant tumor of the autonomic nervous system derived from the neural crest.It is a disease of early childhood with 90% of patients presenting before 5 years of age & almost 50% of patients presenting within the first 2 years.The most common site is adrenal medulla(30%).Metastasis present in 60-70% children,are usually to the skeleton(facial bones,skull),bone marrow and lymph nodes. Reference:Essential pediatrics-Ghai,8th edition,page no:616,617.