This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Enzymes, Subject name: Biochemistry
Enzyme involved in cleavage of glycine in liver mitochondria is 
Select and explain. 
A. Pyruvate dehydrogenase, B. Dihydrolipoyl transacetylase, C. Dihydrolipoyl, D. None of these
C: Dihydrolipoyl
Answer: C: Dihydrolipoyl 
Explanation: Starvation. All the three amino acids undergo similar sequence of reactions. These are summarized in Table 16.2. In this pathway, the second enzyme is a branched chain alpha-keto acid dehydrogenase. It is a complex of decarboxylase, transacylase and dihydrolipoyl dehydrogenase. So, this resembles pyruvate dehydrogenase Only liver mitochondria contain glutamate dehydrogenase (GDH) which deaminates glutamate to alpha-ketoglutarate plus ammonia. So, all amino acids are first transaminated to glutamate, which is then finally deaminated (transamination)Ref: DM Vasudevan, Page no: 200