This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Which of the following is used with local anesthetics to potentiate their action? 
Select and explain. 
A. Adrenaline, B. Sodium bicarbonate, C. Both 1 & 2, D. Dantrolene
B: Sodium bicarbonate
Answer: B: Sodium bicarbonate 
Explanation: Adrenaline is a vasoconstrictor that prolongs duration of local anesthetics & prevents systemic toxicity.
Sodium bicarbonate speeds the action of local anesthetics by increasing the unionized form.