This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.V.S., Subject name: Pediatrics
Dohle bodies are seen in: 
Select and explain. 
A. Neutrophils, B. Macrophages, C. Plasma cells, D. Histiocytes
A: Neutrophils
Answer: A: Neutrophils 
Explanation: a. Neutrophils(Ref: Nelson's 20/e p 1048, Ghai 8/e p 357)In sepsis or severe inflammatory disorders, morphologic changes can be seen in neutrophils, like cytoplasmic vacuoles,Toxic granules (coarser and darker than normal neutrophilic granules) and Dohle bodies, which are patches of dilated endoplasmic reticulum that appear as sky-blue cytoplasmic "puddles."