This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Medicine
Testicular descent is controlled in pa by 
Select and explain. 
A. Insulin like factor 3(INL 3), B. RANKL, C. FSH, D. LH
A: Insulin like factor 3(INL 3)
Answer: A: Insulin like factor 3(INL 3) 
Explanation: Testicular descent through the inguinal canal is controlled in pa by Leydig cell production of insulin-like factor 3 (INSL3), which acts a receptor termed GREAT ( G protein-coupled receptor affecting testis descent). Ref Harrison 20th edi page no 2769