This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Etiological Factors of Neoplasia, Subject name: Pathology
LMP-1 gene plays a role in oncogenesis induced by: 
Select and explain. 
A. Human T cell leukemia virus type I, B. Hepatitis B virus, C. Epstein-Barr virus, D. Human papilloma virus
C: Epstein-Barr virus
Answer: C: Epstein-Barr virus 
Explanation: LMP-1 gene plays a role in oncogenesis induced by EBV. LMP-1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells.