This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: A.N.S., Subject name: Pharmacology
Acetylcholine is not used commersially because: 
Select and explain. 
A. Long duration of action, B. Costly, C. Rapidly destroyed in the body, D. Crosses blood brain barrier
C: Rapidly destroyed in the body
Answer: C: Rapidly destroyed in the body 
Explanation: [Cl (Rapidly destroyed in the body): Ref: 80KDT,435-BB (93-KDT 6th)Acetylcholine is not used because of evanescent and nonselective action* Acetylcholine injected IV. Does not penetrate blood brain barrier and no central effects are seen.* Acetylcholine has such great importance in the body it is not surprising that attempts have been made to use it in therapeutics, But a substance with a huge variety of effects and so rapidly destroyed in the body is unlikely to be useful when given systemically, as its history in psychiatry illustrates.