This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Glaucoma, Subject name: Ophthalmology
Drug kept as a last reso in the management of primary open angle glaucoma is - 
Select and explain. 
A. Latanoprost, B. Topical beta blocker, C. Brimonidine, D. Oral acetazolamide
D: Oral acetazolamide
Answer: D: Oral acetazolamide 
Explanation: Acetazolamide and methazolamide are not recommended for long term use because of their side effects. However, acetazolamide 250 mg Tds may be added to control IOP for sho term Ref :Ophthalmology A K Khurana 6th edition chapter-10 page no :237