This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunology, Subject name: Microbiology
Primary immune response is mediated by? 
Select and explain. 
A. IgE, B. IgM, C. IgA, D. IgD
B: IgM
Answer: B: IgM 
Explanation: The primary immune response is the antibody response to an initial antigen. It is mediated by IgM. With most antigens, IgG is a late antibody and makes it appear after initial immune response which is IgM in nature. Reference : Anathanarayan & paniker's 9th edition, pg no:97, 146 <\p>