This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Medicine
Which of the following DPP IV inhibitors does not require dose modification in Chronic kidney disease patients 
Select and explain. 
A. Sitagliptin, B. Vildagliptin, C. Linagliptin, D. All of the above
C: Linagliptin
Answer: C: Linagliptin 
Explanation: Linagliptin is is DPP IV inhibitors does not require dose modifications in Chronic kidney disease patients and can be used even in stage 5 ckd patients .