This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pathology
Which thyroid carcinoma has amyloid deposition? 
Select and explain. 
A. Anaplastic, B. Follicular, C. Medullary, D. Papillary
C: Medullary
Answer: C: Medullary 
Explanation: Medullary carcinomas of thyroid are neuroendocrine tumours derived from the parafollicular cells or C cells. Microscopically acellular amyloid deposits derived from calcitonin polypeptides are present in the stroma in many cases .Calcitonin is readily demonstrable within the cytoplasm of tumour cells as well as in stromal amyloid by immunohistochemical methods. Ref: Robbins and cotrans 9e Pg 1099