This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Esophageal Disorders - Clinical Presentation, Subject name: Surgery
Pt with complains of dysphagia can take liquid only and history of smoking and weight loss - 
Select and explain. 
A. Achalesia cardia, B. Barrets esophagus, C. Carcinoma esophagus, D. None
C: Carcinoma esophagus
Answer: C: Carcinoma esophagus 
Explanation: Ans. is 'c' i.e., Carcinoma esophagus Predisposing factors for Ca Esophaguso For Adenocarcinoma# Chronic gastric reflux (Barrett's esophagus)o For Squamous cell Ca# Alcohol# Cigarette# Mucosal damage from physical agentsLong term ingestion of hot liquidsLye (caustic) ingestionRadiation-induced stricturesChronic achalasia# Other ingested carcinogensNitrates, nitrites, nitrosaminesSmoked opiatesFungal toxins in pickled vegetables# Plummer-Vinson-Paterson-Kelly syndrome (Esophageal Web + glossitis + Iron deficiency)# Tylosis palmaris et plantaris (Congenital hyperkeratosis and pitting of palms and soles)# Human papilloma virus # Esophageal diverticula # Dietary deficiencies of molvbednum, zinc, vitamin A.# Celiac sprue