This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Bone Tumour, Subject name: Orthopaedics
Multiple punched out lesions in soft skull are seen in 
Select and explain. 
A. Multiple myeloma, B. Secondaries, C. Malignancy, D. Medulloblastoma
A: Multiple myeloma
Answer: A: Multiple myeloma 
Explanation: (Multiple myeloma) (191-92-A)Metastatic bone disease - "Moth eaten appearance" in the cortexMultiple myeloma - reduction in density, myeloma is one of the commonest cause of secondary osteoporosis and vertebral compression fracture* Multiple punched-out defect with no marginal new bone around them