This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nephrotic Syndrome, Subject name: Pathology
A person with radiologically confirmed reflux nephropathy develops nephrotic range proteinuria. Which of the following would be the most likely histological finding in this patient? 
Select and explain. 
A. Focal segmental glomerulosclerosis, B. Nodular glomerulosclerosis, C. Membranous glomerulopathy, D. Proliferative glomerulonephritis with crescents
A: Focal segmental glomerulosclerosis
Answer: A: Focal segmental glomerulosclerosis 
Explanation: Focal segmental glomerulosclerosis It is the most common cause of nephrotic syndrome in adults. Sclerosis is seen in only segment of glomerulus. It is associated with HIV infection, reflux nephropathy & definitive association with sickle cell disease. The patient presents with nephrotic range proteinuria too.