This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
Which of the following drug is not teratogenic? 
Select and explain. 
A. ACE inhibitors, B. Aldosterone, C. AT receptor antagonist, D. Propylthiouracil
D: Propylthiouracil
Answer: D: Propylthiouracil 
Explanation: Propylthiouracil is the drug of choice for hypehyroidism during pregnancy. Carbimazole when used during pregnancy results in aplasia cutis of the neonate. ACEI and ARBs when given during later half of pregnancy results in fetal growth retardation, hypoplasia of organs and fetal death. So it is contraindicated in pregnancy.