This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
A Histopathological examination of an excision specimen from a lesion on the dorsal surface of pensi reveals a papillary lesion with clear vacuolization of epithelial cells on the surface and extension of the hyperplastic epithelium into the underlying tissue. What could be the possible diagnosis? 
Select and explain. 
A. Bowen's disease, B. Erythroplasia of Queyrat, C. Condyloma acuminatum, D. Verrucous carcinoma
D: Verrucous carcinoma
Answer: D: Verrucous carcinoma 
Explanation: Clear vacuolization of the superficial layers of epithelial cells is called Koilocytosis.
Koilocytosis is characteristic of HPV infection. HPV causes both condyloma accuminatum and verrucous carcinoma. But condyloma accuminatum is benign condition, hyperplastic epithelium does not extend into the underlying tissue.