This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Pharmacotherapy in psychiatry, Subject name: Anatomy
which of the following tri cyclic antidepressent used in the management of OCD 
Select and explain. 
A. imipramine, B. amitriptilline, C. amoxapine, D. clomipramine
D: clomipramine
Answer: D: clomipramine 
Explanation: TCA * MECHANISM This is an antidepressant with three rings. It acts by blocking the transpoers of neurotransmitters resulting in increased neurotransmitters in synapse DRUGS AMITRYPTILLINE IMIPRAMINE CLOMIPRAMINE DESIPRAMINE NORIPTILLINE DOXEPINE * USE AMITRYPTILLINE========PAIN WITH DEPRESSION IMIPRAMINE==========CHILDHOOD ENEURESIS CLOMIPRAMINE========OCD * SIDE EFFECTS ANTI HISTAMINERGIC==== sedation, weight gain ANTI MUSCURANIC=======dryness of mouth ANTI ADRENERGIC========hypotension, giddiness SWITCH TO MANIA when used in BIPOLAR DEPRESSION Ref. kaplon and sadock, synopsis of psychiatry, 11 th edition,955