This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Medicine
The subtype of Hodgkin&;s disease, which is histogentically distinct from all the other subtypes is - 
Select and explain. 
A. Lymphocyte predominant, B. Nodular sclerosis, C. Mixed cellularhy, D. Lymphocyte depleted
A: Lymphocyte predominant
Answer: A: Lymphocyte predominant 
Explanation: <p>The lympocytic predominance type of HD is characterised by proliferation of small lympocytes admixed with a varying number of histiocytes.Polypoid ( or popcorn )Reed Sternberg cells are seen in thus type of HD with lobulated nucleus in the shape of popcorn.</p><p>Reference :Harsh Mohan textbook of pathology 6th edition pg no 371</p>