This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Vitreous and retina, Subject name: Ophthalmology
Mizuo-phenomenon is seen in - 
Select and explain. 
A. Fundus albipathicus, B. Fundus flavimaculatus, C. Oguchis disease, D. Choroideremia
C: Oguchis disease
Answer: C: Oguchis disease 
Explanation: Oguchi disease is characterized by a golden-brown fundus with a yellow-gray 'metallic' sheen in the light-adapted state. After complete dark adaptation (3 to 12 hours), the fundus appears normal, and this disappearance of the shiny, yellow, fundus reflex is called the Mizuo-Nakamura phenomenon.