This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Wounds, Tissue Repair & Scars, Subject name: Surgery
Following admission to the emergency department, a 26-year-old woman with severe menorrhagia states that both her father and sister have a bleeding disorder. The hemostatic disorder transmitted by autosomal-dominant mode is which of the following? 
Select and explain. 
A. Factor X deficiency, B. von Willebrand's disease, C. Factor VIII deficiency (true hemophilia), D. Factor IX deficiency (Christmas disease)
B: von Willebrand's disease
Answer: B: von Willebrand's disease 
Explanation: von Willebrand disease is the most common hemostatic disorder transmitted by autosomal- dominant mode. Other disorders transmitted by this mode are hereditary hemorrhagic telangiectasia and factor XI deficiency. Diseases transmitted by an autosomal-recessive mode are factor X, factor V, factor VII, and factor I deficiencies. Factor VIII (true hemophilia) and factor IX (Christmas disease) deficiencies are sex-liked recessive.