This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
HBV Replication is indicated by all of the following, Except: 
Select and explain. 
A. HBV DNA, B. DNA polymerase, C. HBe Ag, D. HBs Ag
D: HBs Ag
Answer: D: HBs Ag 
Explanation: Answer is D (HBs Ag) HBsAg is not a marker for active HBV Replication. Serological markers for active viral replication include HBe Ag, presence of DNA polymerase and circulating HBV DNA.