This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Conn's syndrome is associated with all the following, except: 
Select and explain. 
A. Hypeension, B. Hypokalemia, C. Muscle weakness, D. Metabolic acidosis
D: Metabolic acidosis
Answer: D: Metabolic acidosis 
Explanation: Conn's syndrome is associated with metabolic alkalosis, not with metabolic acidosis. Conn's syndrome refers to primary hyperaldosteronism due to an adrenal adenoma. Increased aldosterone secretion results in hypokalemia from increased excretion of potassium and metabolic alkalosis due to increased hydrogen ion secretion. Ref: Harrisons Internal Medicine, 18th Edition, Pages 2949-2951 ; Hypeension By Joseph Cheriyan, Page 148 ; Mosby's Handbook Of Diseases By Rae Langford, 3rd Edition, Page 28