This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Peptic Ulcer Disease, Subject name: Medicine
Which is true regarding Barrett's esophagus? 
Select and explain. 
A. Squamous metaplasia of lower esophagus, B. Seen mainly in females, C. Premalignant, D. Responds to conservative management
C: Premalignant
Answer: C: Premalignant 
Explanation: Barrett's esophagus Age - 55-65 years. 2:1 male-to-female ratio, with white males making up more than 80% of cases. Columnar metaplasia of lower esophagus Does not respond to any treatment. Premalignant condition diagnosed with UGIE with biopsy. If high grade dysplasia is found , go for fuher intervention