This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
Chances of an offspring being affected when one parent is autosomal dominant heterozygote? 
Select and explain. 
A. 25%, B. 50%, C. 100%, D. None
B: 50%
Answer: B: 50% 
Explanation: Transmission patterns of single-gene disorders Disorders of autosomal dominant inheritance are manifested in the heterozygous state. When an affected person marries an unaffected person, every child has one chance in two of having the disease. So the option is 50%.Robbins basic pathology; 9th edition; page no 219