This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunomodulators, Subject name: Pharmacology
What is true about thalidomide 
Select and explain. 
A. It exes antitumour activity in some solid malignant tumours, B. It exes antileprotic action, C. It ameliorates cancer associated cachexia, D. All of the above
C: It ameliorates cancer associated cachexia
Answer: C: It ameliorates cancer associated cachexia 
Explanation: Thalidomide It is reintroduced as immunomodulator. uses:- 1)Angiogenesis inhibitor antitumour activity 2)anxiolytic 3)antiemetic 4)adjuvant analgesic/antipyretic propey 5 )improves cancer associated cachexia 6) used in erythema nodosum leprosum 7) multiple myeloma Mech of action:- It acts by suppressing TNFa and by modulating IL-2. contraindication:- In Pregnancy due to phocomelia(seal like limbs). Ref:- kd tripathi; pg num:-877