This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: nutrition and digestion, Subject name: Biochemistry
Which of the following plasma levels increase markedly in starvation? 
Select and explain. 
A. Glucose, B. Nonesterified fatty acids, C. Ketone bodies, D. All the above
C: Ketone bodies
Answer: C: Ketone bodies 
Explanation: There is a small fall in plasma glucose in the fasting state, and then little change as fasting is prolonged into starvation. Plasma nonesterified fatty acids increase in fasting but then rise little more in starvation. As fasting is prolonged, the plasma concentration of ketone bodies (acetoacetate and 3-hydroxybutyrate) increases markedly. Reference: Harper; 30th edition; Chapter 14; Page no: 148