This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Disorders of Amino acid Metabolism, Subject name: Pediatrics
If the tyrosinase gene is defective, it results in: 
Select and explain. 
A. Lack of pigmentation, B. Maple syrup urine disease, C. Phenylketonuria, D. Kidney stones
A: Lack of pigmentation
Answer: A: Lack of pigmentation 
Explanation: Defect in Tyrosinase leads to Albinism, which presents with hypopigmentation.