This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Skin
The propoion of which of the acids are increased in acne comedones? 
Select and explain. 
A. Linolenic acid, B. Palmitic acid, C. Acetic acid, D. Linoleic acid
B: Palmitic acid
Answer: B: Palmitic acid 
Explanation: In acne comedones the propoion of linoleic acid is markedly decreased, while palmitic acid is significantly increased. Decreased propoion of linoleic acid, markedly suppresses neutrophil reactive oxygen species (ROS) generation and phagocytosis and contribute to the worsening of acne inflammation.