This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Adverse Drug Effect, Subject name: Pharmacology
Ototoxicity caused by: 
Select and explain. 
A. Vancomycin, B. Streptomycin, C. Ampicillin, D. Rifampicin
B: Streptomycin
Answer: B: Streptomycin 
Explanation: Ans. (b) StreptomycinRef : KDT 6th ed. / 743-44* Streptomycin has been assigned to pregnancy category D by the FDA.* Streptomycin crosses the placenta; reported cord concentrations have been equal to or less than the mothers serum concentration.* There are reports of fetal eighth cranial nerve damage with subsequent bilateral deafness. Most authorities, including the Centers for Disease Control and the American Thoracic Society, discourage the use of streptomycin during pregnancy due to the risk of fetal ototoxicity.