This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Blood, Subject name: Medicine
Schistocytes are seen in: 
Select and explain. 
A. HUS, B. TTP, C. DIC, D. All of the above
D: All of the above
Answer: D: All of the above 
Explanation: Ans. (d) All of the aboveRef: Harrison's lTh ed. Ch. 109* Schistocytes are fragmented part of a red blood cells which are typically irregularly shaped, jagged, and have two pointed ends. A true schistocyte does not have central pallor. They are sometimes referred to as "helmet cells"* The presence of schistocytes on the peripheral blood smear suggests red blood cell injury from damaged endothelium and is a characteristic feature of microangiopathic hemolytic anemia.* Microangiopathic hemolytic anemia is an infrequent cause of Coombs-negative intravascular hemolytic anemia, and its causes include:# Thrombotic thrombocytopenic purpura# Hemolytic uremic syndrome# Disseminated intravascular coagulation# Defective valvular prosthesis.