This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Medicine
Diagnosis of irritable bowel syndrome is based on the following criteria EXCEPT-(ROME-III) 
Select and explain. 
A. Recurrent abdominal pain or discomfo at least 3 days per month in the last 3 month, B. Improvement with defecation, C. Onset associated with a change in frequency, form and appearance of stool, D. Nocturnal symptoms and hematochezia at least once in last 3 months
D: Nocturnal symptoms and hematochezia at least once in last 3 months
Answer: D: Nocturnal symptoms and hematochezia at least once in last 3 months 
Explanation: <p>Davidson&;s principles and practice of medicine 22nd edition. Rome III criteria. * abdominal pain or discomfo at least 3 days in last 3 months associated with 2 or more of the following. #improvement with defecation. #change in frequency of stool. #change in appearance of stool. </p>