This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti Microbial, Subject name: Pharmacology
Not true about clofazamine - 
Select and explain. 
A. Used in DLE, B. Causes ichthyosis and hyperpigmentation, C. Interferes DNA synthesis, D. Used in lepra reaction
A: Used in DLE
Answer: A: Used in DLE 
Explanation: Ans. is 'a' i.e., Used in DLE Clofazimineo Clofazimine is a leprostatic drug.o It acts by interfering the template function of DNA.o Adverse effects of clofazimine Skin - Reddish-black discolouration of skin, dryness of skin and itching, Discolouration of hair and body secretions, acneform eruptions and phototoxicity, conjuctival pigmentation. GIT- Enteritis with loose stools, nausea, abdominal pain, anorexia and weight loss.Remember - Clofazimine has antiinflammatory property can be used in lepra reaction.