This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nephrotic and Nephritic syndrome, Subject name: Medicine
A patient with clinical features of Glomerulonephritis is having granular staining on immune-fluorescence. All of the following causes have normal C3 except? 
Select and explain. 
A. IgA Nephropathy, B. Henoch scholein purpura, C. Fibrillary GN, D. Cryoglobulinemia
D: Cryoglobulinemia
Answer: D: Cryoglobulinemia 
Explanation: * Granular pattern on immunofluorescence is seen in immune complex mediated Glomerulonephritis * Cryoglobulinemia leads to low C3 and C4 Immune complex GN Low C3 Normal C3 PSGN MPGN SLE IE Cryoglobulinemia IgA nephropathy HSP Fibrillary and immunotactoid Glomerulonephritis