This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Trauma, Subject name: Surgery
In crush syndrome what is noted 
Select and explain. 
A. Renal failure, B. Liver failure, C. Cardiac failure, D. Endocrine crisis
A: Renal failure
Answer: A: Renal failure 
Explanation: In a crush injury, crushing of muscle leads to a reperfusion injury when the casualty is rescued.This releases myoglobin and vasoactive mediators into the circulation.It also sequesters many litres of fluid, reducing the effective intravascular volume and resulting in renal vasoconstriction and ischaemia. The myoglobinuria leads to renal failure from tubular obstructionBailey and Love 26e pg: 430