This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General anatomy, Subject name: Anatomy
In genetic deficiency of MPO the increased susceptibility to infections is due to 
Select and explain. 
A. Defective production of prostaglandin, B. Defective rolling of neutrophil, C. Inability to produce hydroxyl halide radicals, D. Inability to produce hydrogen peroxide
C: Inability to produce hydroxyl halide radicals
Answer: C: Inability to produce hydroxyl halide radicals 
Explanation: Ref Robbins 8/e p53 ,56,9/e p76 Myeloperoxidase (MPO) is a hemoprotein expressed in azurophilic granules of neutrophils and in the lysosomes of monocytes. The enzyme has strong antibacterial propeies and is unique in its ability to generate potent bactericidal compounds such as hypochlorous acid (HOCl) from hydrogen peroxide and the halide, chloride