This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Musculoskeletal system, Subject name: Pathology
SS18-SSX1 gene is associated with 
Select and explain. 
A. Liposarcoma, B. Rhabdomyosarcoma, C. Synol sarcoma, D. Ewing sarcoma
C: Synol sarcoma
Answer: C: Synol sarcoma 
Explanation: TumorCytogenetic AbnormalityGene fusionProposed functionSynol sarcomat(x;18)(p11;q11)SS18-SSX1SS18-SSX2SS18-SSX4Chimeric transcription factors, interrupts cell cycle controlReference: Robbins and Cotran Pathologic Basis of Disease; 9th edition; Chapter 26; Bones, Joints, and Soft Tissue Tumors