This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Systemic Lupus Erythematous, Subject name: Medicine
Among patients with polymyositis, which one of the following auto-antibodies is associated with an increased risk of interstitial lung disease? 
Select and explain. 
A. Anti-CCP antibody, B. Anti ds DNA antibody, C. Anti cardiolipin antibody, D. Anti-Jo-1 antibody
D: Anti-Jo-1 antibody
Answer: D: Anti-Jo-1 antibody 
Explanation: Myositis Specific Antibodies Anti Jo-1 and anti synthetase antibodies Polymyositis and dermatomyositis with Interstitial lung disease, ahritis, mechanic's hands Anti-Mi-2 Dermatomyositis with rash Anti MDAS Dermatomyositis with rapidly progressive lung disease Anti-10 Juvenile dermatomyositis Anti-Signal recognition paicle Severe acute necrotizing myopathy