This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anesthesia, Subject name: Pharmacology
post dural (Spinal) puncture headache is due to: 
Select and explain. 
A. Seepage of CSF, B. Fine needle, C. Toxic effects of the drugs, D. Traumatic damage to nerve roots
A: Seepage of CSF
Answer: A: Seepage of CSF 
Explanation: Headache is due to of CSF and can be treated with analgesics. Post-dural-puncture headache (PDPH) is a complication of puncture of the dura mater (one of the membranes that surround the brain and spinal cord). ... It is a common side-effect of spinal anesthesia and lumbarpuncture. From padmaja 4th edition Page no 205