This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: JIPMER 2017, Subject name: Pathology
Which of the following is a manifestation of 22q11 mutation syndrome? 
Select and explain. 
A. Hypercalcemia, B. Conotruncal abnormalities, C. Thymic hyperplasia, D. Dysmorphogenesis of the 1st and 2nd pharyngeal pouches
B: Conotruncal abnormalities
Answer: B: Conotruncal abnormalities 
Explanation: Chromosome 22q11.2 deletion syndrome encompasses a spectrum of disorders that result from a small deletion of band q11.2 on the long arm of chromosome 22. It is also called as Velocardiofacial syndrome or DiGeorge syndrome It is characterized by Dysmorphogenesis of the 3rd and 4th pharyngeal pouches resulting in following features: C: Cardiac anomaly/cono-truncal anomaly A:Abnormal facies T: Thymic hypoplasia/T cell abnormality C: Cleft palate H: Hypocalcemia 22: Chromosome 22