This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
Dysplasia is characterized by all except 
Select and explain. 
A. High nuclear to-cytoplasmic ratio, B. Loss of architecture(DNB Nov. 13 Pattern, C. Pleomorphism, D. Invasion
D: Invasion
Answer: D: Invasion 
Explanation: Robbins basic pathology 9th edition page no 166 When dysplastic changes are marked and involve the entire thickness of the epithelium, the lesion is referred to as carcinoma in situ, a preinvasive stage of cancer.