This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Bacteria, Subject name: Microbiology
All are true about FTA-ABS in Syphilis, except: 
Select and explain. 
A. FTA - ABS becomes negative after treatment, B. Present in secondary syphilis, C. It is a specific test, D. May be positive in Lyme's disease
A: FTA - ABS becomes negative after treatment
Answer: A: FTA - ABS becomes negative after treatment 
Explanation: Ans. is 'a' i.e., FTA-ABS becomes negative after treatment(Ref: Ananthanarayan, 9th/e, p. 370,375 and 8th/e, p. 376-377; Harrison, 18th/e, p. 1385, 17th/e, p. 1043, 19th/e, p. 1132)Specific treponemal tests (FTA-ABS, TPHA, TPI) are of little value as indicators of clinical cure, as they tend to remain positive in spite of treatment because of it. Specific tests are not used in monitoring of the treatment. VDRL or RPR can be used for treatment monitoring as specific tests remain positive (reactive) after the treatment.