This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous (Pharmacology), Subject name: Pharmacology
Drug therapy used in treatment of Wernicke's encephalopathy 
Select and explain. 
A. Diazepam, B. Disulfiram, C. Thiamine, D. Cyanocobalamin
C: Thiamine
Answer: C: Thiamine 
Explanation: (C) Thiamine # Thiamin deficiency can result in three distinct syndromes:> A chronic peripheral neuritis, beriberi, which may or may not be associated with heart failure and edema; acute pernicious (fulminating) beriberi (shoshin beriberi), in which heart failure and metabolic abnormalities predominate, without peripheral neuritis; and Wernicke's encephalopathy with Korsakoff's psychosis, which is associated especially with alcohol and drug abuse.> Therapeutic uses of Thiamine: most neurological symptoms in chronic alcoholics are due to thiamine deficiency -peripheral neuritis Wernick's encephalopathy, Korskoffs psychosis: give 100 mg/day paranterally.