This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Medicine
AML transformation common in 
Select and explain. 
A. Aplastic anemia, B. MDS, C. Megakaryocytic thrombocytopenia, D. CLL
A: Aplastic anemia
Answer: A: Aplastic anemia 
Explanation: Aplastic anemia to AML Aplastic anemia (AA) is a clinical syndrome of peripheral blood pancytopenia and a hypocellular bone marrow. Immunosuppressive therapy is a key treatment strategy for AA. Genomic instability in AA does not appear to be a rare event. AA evolves into acute myeloid leukemia (AML) in 5-15% of all cases Ref Davidson 23rd edition pg 969