This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Autonomic nervous system, Subject name: Pharmacology
Botulinum toxin produces skeletal muscle paralysis by: 
Select and explain. 
A. Enhancing release of norepinephrine, B. Inhibiting release of acetylcholine, C. Direct damage to nerve endings, D. Producing hemolysis
B: Inhibiting release of acetylcholine
Answer: B: Inhibiting release of acetylcholine 
Explanation: Ref: KD Tripathi pharmacology 7th edition (page.no: 99) Botulinum toxin A and B are highly potent exotoxins produced by Clostridium botulinum that is responsible for Botulism. These neurotoxic proteins cause long-lasting loss of cholinergic transmission by interacting with an axonal protein involved in the exocytic release of Ach