This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of carbohydrate, Subject name: Biochemistry
Fructose intolerance is due to deficiency of 
Select and explain. 
A. Aldolase B, B. F ructokinase, C. Triokinase, D. Aldolase A
A: Aldolase B
Answer: A: Aldolase B 
Explanation: Fructose intolerance is due to deficiency of aldolase-B.Incidence out of 1 is 20,000.It is an autosomal recessive inborn error of metabolism.Fructose-1-phosphate cannot be metabolized.Accumulation of fructose -1-phosphate will inhibit glycogen phosphorylase.Ref: DM Vasudevan, 7th edition, page no: 144