This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General Pharmacology, Subject name: Pharmacology
Hemodialysis is useful in all of the following except: 
Select and explain. 
A. Barbiturate poisoning, B. Methanol poisoning, C. Salicylate poisoning, D. Digoxin poisoning
C: Salicylate poisoning
Answer: C: Salicylate poisoning 
Explanation: Ans. C. Salicylate poisoningDialysis will not remove drugs which have high Vda. Dialysis will not remove drugs which have high plasma protein bindingb. Digoxin, diazepam, organophosphates have high Vd.Drugs having high Vd are: (hemodialysis is ineffective)a. Dialysis--Diazepamb. Ko--Kerosene poisoningc. A--Amphetamined. V--Verapamile. 0--Organophosphorus, opioidsf. I--Imipramineg. uD--Digitalis