This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Sedative-Hypnotics and Parkinsonism, Subject name: Pharmacology
All are true statements regarding Lemborexant except : 
Select and explain. 
A. It is used in the treatment of Insomnia, B. It is an orexin receptor agonist, C. It is useful in patients with difficulties with sleep onset/maintenance, D. The most common adverse effect is somnolence
B: It is an orexin receptor agonist
Answer: B: It is an orexin receptor agonist 
Explanation: Lemborexant FDA approved drug for the treatment of insomnia which got its approval after two Phase III clinical trials namely SUNRISE I and SUNRISE II. Useful in insomnia ,characterized by difficulties with sleep onset and/or sleep maintenance. Orexin neuropeptide signaling system plays a role in wakefulness. Blocking the binding of wake-promoting neuropeptides orexin A and orexin B to orexin receptors OX1R and OX2R is thought to suppress wake drive. Lemborexant binds to orexin receptors OX1R and OX2R and acts as a competitive antagonist with stronger inhibition effect to OX2R most common adverse effect is somnolence