This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pharmacology, Subject name: Pharmacology
Design of the study aimed to assess the maximum tolerable dose of a new drug is? 
Select and explain. 
A. Case Control study, B. Phase II Randomized control trial (RCT), C. Phase I trial, D. Phase III Randomized control trial (RCT)
C: Phase I trial
Answer: C: Phase I trial 
Explanation: The highest dose of a drug that does not cause unacceptable side effects. It is determined in phase 1 clinical trials by testing increasing doses on different groups of people until the highest dose with acceptable side effects is found. Also called MTD. Pg.no.80 K D Tripathi Seventh edition