This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
About biotransformation not true ? 
Select and explain. 
A. Active metabolite generation, B. Polar to less polar, C. Less polar to more polar, D. Generate active drug from prodrug
B: Polar to less polar
Answer: B: Polar to less polar 
Explanation: Ans. is 'b' i.e., Polar to less polar