This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Enzymes, Subject name: Biochemistry
Succinate dehydrogenase is inhibited by 
Select and explain. 
A. Fluoroacetate, B. Cyanide, C. Arsenite, D. Malonate
D: Malonate
Answer: D: Malonate 
Explanation: Succinate is dehydrogenated to fumarate, an unsaturated dicarboxylic acid, by succinate dehydrogenase (step 6, Fig.18.2). The hydrogen atoms are accepted by FAD. The FADH2 then enters into ETC to generate ATPs. The enzyme is a flavoprotein. The succinate dehydrogenase is competitively inhibited by malonateRef: DM Vasudevan, Page no: 219