This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy, Subject name: Pharmacology
WhiCh of the following drugs is most likely to be effective against multi drug resistant strains big M. Tuberculosis including those resistant to Streptomycin 
Select and explain. 
A. Amikacin, B. Claruthromycin, C. Gentamicin, D. Spectinomycin
A: Amikacin
Answer: A: Amikacin 
Explanation: Refer KDT 6/e p 744 Amikacin is an aminoglycoside that us most resistant to inactivating enzymes. It is used as a second line antitubercular drug It can be used in MDR tuberculosis management