This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Anaesthesia
Which anaesthetic modality is to be avoided in sickle cell disease – 
Select and explain. 
A. General anaesthesia, B. Brachial plexus block, C. I.V. Regional Anaesthesia, D. Spinal
C: I.V. Regional Anaesthesia
Answer: C: I.V. Regional Anaesthesia 
Explanation: None