This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Massive edema in body in a patients of burns is due to 
Select and explain. 
A. Cardiac dysfunction due to release of cardiac depressants, B. Basement membrane injury causing altered pressure gradient, C. Acute Renal failure, D. Fluid overload
B: Basement membrane injury causing altered pressure gradient
Answer: B: Basement membrane injury causing altered pressure gradient 
Explanation: Massive edema in burns is due to altered pressure gradient because of injury to basement membrane.