This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Skin
Earliest feature of Tuberous sclerosis is: 
Select and explain. 
A. Angiofibroma, B. Shagreen patch, C. Ash leaf spot, D. Neurofibroma
C: Ash leaf spot
Answer: C: Ash leaf spot 
Explanation: Ash leaf spot