This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Which of the following statements about coagulation factor VII is not true? 
Select and explain. 
A. Deficiency is associated with prolonged APTT, B. Deficiency can be managed by Fresh Frozen plasma, C. Deficiency is inherited as an Autosomal Recessive trait, D. Has a shoer half life in comparison to Hageman factor (XII)
A: Deficiency is associated with prolonged APTT
Answer: A: Deficiency is associated with prolonged APTT 
Explanation: Factor VII is a 56kd single chain, vitamin K dependent zymogen component of the extrinsic pathway of blood coagulation. So, its deficiency is associated with prolongation of PT not APTT. APTT is prolonged in case of deficiency of coagulation factors involved in intrinsic pathway. Ref: Autoantibodies By James B. Pete, Pages 179-80