This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
A patient of 47 XXY karyotype presents with features of hypogonadism; likely diagnosis is : 
Select and explain. 
A. Turners syndrome, B. Klinefelters syndrome, C. Edwards syndrome, D. Down syndrome
B: Klinefelters syndrome
Answer: B: Klinefelters syndrome 
Explanation: Ans. is b i.e. Klinefelter syndrome Extra Edge : Klinefelter's syndrome ? Seen in 1 : 500 malesdeg Karyotype 47XXY (1 barr body present)deg Phenotype maledeg Gonads : Testis, small but normally placeddeg Genitalia : Penis is small/ normal size. Gynaecomastia is frequently seendeg Sterility is commondeg Voice : High pitched and appearance may be eunuchoid Patient is mentally defective or delinquentdeg. Testicular biopsy shows hyaline degeneration of seminiferous tubules and over growth of leydig cells, as a result of which stelirity is so often the presenting symptom The person should be broughtup as male.deg Treatment with testosterone may help.