This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: CVS Embryology, Subject name: Anatomy
Transposition of the great aeries is a cardiac malformation that involves which of the following septa? 
Select and explain. 
A. Aoicopulmonary septum, B. Atrial septum, C. Atrioventricular septum, D. Interventricular septum
A: Aoicopulmonary septum
Answer: A: Aoicopulmonary septum 
Explanation: Transposition of great vessels involves the Aoicopulmonary septum due to improper spiraling of AP septum fig;- transposition of great aeries Other AP septum disease:- 1.PTA(persistent truncus aeriosus) - due to absence of migration of NCC to truncus aeriosus. 2. TOF( tetrology of fallot):- due to anterior migration of AP septum. Defect in atrial septum lead to ASD. Defect in interventricular septum lead to VSD.