This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetic Approach to Pediatric Medicine, Subject name: Pediatrics
Klinefelter's syndrome is diagnosed by: 
Select and explain. 
A. Karyotyping, B. Ultrasound abdomen, C. Triple test, D. Echocardiography
A: Karyotyping
Answer: A: Karyotyping 
Explanation: Ans. A. KaryotypingBlood or urine samples can reveal abnormal hormone levels that are a sign OF Klinefelter syndrome. Chromosome analysis. Also called karyotype analysis, this test is used to confirm a diagnosis of Klinefelter syndrome.