This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Which drug is contraindicated in patients allergic to sulphonamides ? 
Select and explain. 
A. Brizolamide, B. Brimonidine, C. Zonisamide, D. Bimatoprost
C: Zonisamide
Answer: C: Zonisamide 
Explanation: Ans. is 'c' i.e., Zonisamide Zonisamide is a sulfonamide medication used for the treatment of seizures. It has been associated with severe skin reactions, those typically seen with sulfa reactions. This medication should not be used in sulfa-allergic patients.