This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Misc. (R.B.C), Subject name: Pathology
All of the following statements about iron deficiency anemia are true except? 
Select and explain. 
A. Latent iron deficiency is most common presentation in India, B. Transferrin saturation is less than 16%, C. Serum ferritin is the earliest marker, D. It can present without detectable abnormalities
A: Latent iron deficiency is most common presentation in India
Answer: A: Latent iron deficiency is most common presentation in India 
Explanation: Ans. (a) Latent iron deficiency is most common presentation in India(Ref: Robbins 9th/pg 649-652; 8th/pg 659-662)a. False- Manifest (Anemia), not Latent (pre-anemia) iron deficiency is most common presentation in Indiab. True- Saturation of transferrin is always reduced to <16%. At this level of saturation, iron delivery to erythroid precursors is limited.c. True-Most sensitive marker in iron deficiency anemia is Serum ferritind. True-The onset of iron deficiency anemia is usually insidious & progression of symptoms is gradual. As a result, patients accommodate remarkably well to advancing anemia & may not present with clinical features