This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Most pathognomonic sign of irreversible cell injury: 
Select and explain. 
A. Amorphous densities in mitochondria, B. Swelling of the cell membrane, C. Ribosomes detached from endoplasmic reticulum, D. Clumping of nuclear chromatin
A: Amorphous densities in mitochondria
Answer: A: Amorphous densities in mitochondria 
Explanation: . Amorphous densities in mitochondria