This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Blood Vessels, Subject name: Pathology
Angiogenesis is 
Select and explain. 
A. Formation of the new blood vessels, B. Repair by connective tissues, C. Formation of the blood clot, D. All of the above
A: Formation of the new blood vessels
Answer: A: Formation of the new blood vessels 
Explanation: (Formation of the new blood vessels) (71-72-R) (70-72- Basic pathology 8th)ANGIOGENESIS or neovascularization by which preexisting vessels send out capillary sprouts to produce new vessels.Angiotensis is a critical process in the healing at sites of injury in the development of collateral circulations at sites of ischemia, and in allowing tumours to increase in size beyond the constraints of their original blood supply.* Steps in the process of angiogenesis1. Basement membrane and extracellular matrix degradation2. Endothelial migration3. Endothelial proliferation (mitosis)4. Organisation and maturation including the recruitment of vascular pericytes or smooth muscle cells5. Increased permeability due to intercellular gaps and increased transcytosis.Thrombosis - Formation of the blood clot (thrombus)Fibrosis - Repair by connective tissues