This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Anaesthesia
Earliest and most pathognomic feature of malginant hyperthermia is 
Select and explain. 
A. Increased temperature, B. Increased end-tidal CO2, C. Increased heart rate, D. Increased respiratory rate
B: Increased end-tidal CO2
Answer: B: Increased end-tidal CO2 
Explanation: Increased CO2 production is earliest sign of malignant hyperthermia.