This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti Microbial, Subject name: Pharmacology
Mechanism of action of Dabigtran - 
Select and explain. 
A. Activation of plasmin, B. Direct inhibition of thrombin, C. Indirect inhibition of thrombim, D. Inactivation of vitamin K dependent facters
B: Direct inhibition of thrombin
Answer: B: Direct inhibition of thrombin 
Explanation: Ans. is 4b' i.e., Direct inhibition of thrombin AnticoagulantsOrali) Vitamin K inhibitors (Traditional oral anticoagulants):- Warfarin, dicumarol, acenocoumarol, ethylbiscoumacetate, phenindione.ii) Facto Xa inhibitors:- Rivaroxaban, Apixaban.iii) Direct thrombin inhibitors:- Ximelaeatran. dabiyatran.Parentrali) Indirect thrombin inhibitors:- Unfractionated heparin, low molecular weight heparin (e.g. Enoxaparin, reviparin etc), Fondaparinux, Idraparinux.ii) Direct thrombin inhibitors:- Hirudin, Lepirudin, bivalirudin, argatroban, melagatron, ximelagatron.