This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Anaesthesia
Depth of anaesthesia by inhalation anaesthetics depends upon 
Select and explain. 
A. Respiratory minute volume, B. Solubility of anaesthetic agent in blood, C. Blood concentration of anaesthetic agent, D. All of the above
D: All of the above
Answer: D: All of the above 
Explanation: (D) All of the above # Depth of anaesthesia depends on the potency of the agent (MAC is an index of potency) and its partial pressure (PP) in the brain, while induction and recovery depend on the rate of change of PP in the brain.> Factors affecting PP of anaesthetic attained in brain are: PP of anaesthetic in the inspired gas Pulmonary ventilation Alveolar exchange Solubility of anaesthetic in blood Solubility of anaesthetic in tissue Cerebral blood flow