This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Lipids, Subject name: Biochemistry
Which enzyme defect causes Tay Sach's disease? 
Select and explain. 
A. b glucosidase, B. a galactosidase, C. Hexosaminidase A, D. B galactosidase
C: Hexosaminidase A
Answer: C: Hexosaminidase A 
Explanation: Ans. is 'c' i.e., Hexosaminidase ALipid storage disordersDisorderEnzyme defectGaucher's diseaseb glucosidaseNiemann Pick diseaseSphingomyelinaseFabry's diseasea galactosidaseGM1 gangliosidosisb galactosidaseGM2 gangliosidosisHexosaminidase ASandhoff s diseaseHexosaminidase A and BKrabbe's diseaseGalactosyl ceramidaseMetachromatic leukodystrophyAryl Sulfatase AFarber's diseaseCeramidaseWolman's diseaseAcid lipase