This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
The maximum dosage of local anesthetic agent like lidocaine must be reduced when used in combination with a CNS and/respiratory depressant because, it may result in: 
Select and explain. 
A. Seizures, B. Coma, C. Death, D. All of the above
D: All of the above
Answer: D: All of the above 
Explanation: None