This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of carbohydrate, Subject name: Biochemistry
Cancer cells derive nutrition from 
Select and explain. 
A. Glycolysis, B. Oxidative phosphorylation, C. Gluconeogenesis, D. Glycogenolysis
A: Glycolysis
Answer: A: Glycolysis 
Explanation: In fast-growing cancer cells, glycolysis proceeds at a high rate, forming large amounts of pyruvate, which is reduced to lactate and expoed. This produces a relatively acidic local environment in the tumor, which may have implications for cancer therapy. The lactate is used for gluconeogenesis in the liver, an energy-expensive process, which is responsible for much of the hypermetabolism seen in cancer cachexia. Reference: Harper; 30th edition; Page no: 168