This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
In oesophageal ca which Neoadjuvant chemotherapy is used - 
Select and explain. 
A. Cisplatin, B. Cyclophosphamide, C. Doxorubicin, D. Methotrexate
A: Cisplatin
Answer: A: Cisplatin 
Explanation: Sabiston writes-"Since its introduction in 1980, cisplatin has emerged as the cornerstone of combination therapy in esophageal cancer.
As a single agent, it has a response rate of 25% to 30%. Given in combination with 5-fluorouracil, a response rate of 50% may be achieved, and this is an established chemotherapeutic regimen for esophageal cancer."