This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Ophthalmology
Roth's spot are seen in: March 2007 
Select and explain. 
A. SABE, B. Trauma, C. Hypeension, D. Trachoma
A: SABE
Answer: A: SABE 
Explanation: Ans. A: SABE "Roth's spots" are retinal hemorrhages with white or pale centers composed of coagulated fibrin and are typically observed fundoscopy, using an ophthalmoscope. They are usually caused by immune complex mediated vasculitis often resulting from bacterial endocarditis. Roth's spots may be observed in leukemia, diabetes, subacute bacterial endocarditis, pernicious anaemia, ischemic events associated with elevated venous pressure and systemic vascular conditions with capillary fragility and rarely in HIV retinopathy.