This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Disorders of Adrenal Gland, Subject name: Medicine
Decreased plasma renin activity is seen in: 
Select and explain. 
A. Primary hyperaldosteronism, B. Baer syndrome, C. Pregnancy induced Hypeension, D. Secondary aldosteronism
A: Primary hyperaldosteronism
Answer: A: Primary hyperaldosteronism 
Explanation: Primary hyperaldosteronism is due to bilateral adrenal hyperplasia or due to adrenal adenoma. Both these conditions are autonomous and lead to aldosterone production in excess. The R.A.A.S system negative feedback will result in decrease in renin production. Low renin Hypeension is a feature of primary hyperaldosteronism. Causes of low renin hypeension Liddle syndrome Conn's syndrome Mineralocoicoid receptor mutation Apparent mineralocoicoid excess (AME) Glucocoicoid resistance Gordon syndrome Congenital adrenal hyperplasia (CAH)