This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Most specific antibody seen in RA 
Select and explain. 
A. Anti CCP, B. Rheumatoid factor, C. ANA, D. Anti dsDNA
A: Anti CCP
Answer: A: Anti CCP 
Explanation: Answer- A. Anti CCPThe presence of serum anti-CCP antibodies has about the same sensitivity as serum RF for the diagnosis of RA.However, its diagnostic specificity approaches 95% (most specific for RA), so a positive test for anti-CCP antibodies in the setting of an early inflammatory ahritis is usefrrlfor distinguishing RA from other forms of ahritis.