This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Liver disorders, Subject name: Pediatrics
In neonatal cholestasis, direct bilirubin is: 
Select and explain. 
A. >10%, B. >15%, C. >20%, D. >25%
C: >20%
Answer: C: >20% 
Explanation: Neonatal cholestasis is defined biochemically as prolonged elevation of the serum levels of conjugated bilirubin (> 2 mg/dl or >20% of total bilirubin level) beyond the 1st 14 days of life.