This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Respiratory system, Subject name: Physiology
Comparison of the apex of the lung, the base of the lung has 
Select and explain. 
A. High pulmonary aerial pressure O2, B. High pulmonary aerial pressure CO2, C. High ventilation / perfusion ratio, D. Same ventilation / perfusion ratio
C: High ventilation / perfusion ratio
Answer: C: High ventilation / perfusion ratio 
Explanation: Overall, perfusion increases more than ventilation at the base of the lung, resulting in lower V/Q ratios in the base of the lung compared to the apex. In a healthy individual, the V/Q ratio is 1 at the middle of the lung, with a minimal spread of V/Q ratios from 0.3 to 2.1 from base to apex Ref: guyton and hall textbook of medical physiology 12 edition page number:332,333,334