This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nutrition and Metabolic disorders,Systemic conditions ,Genodermatoses, Connective tissue disorders,Photodermatoses, Subject name: Dental
Which of the following is associated with reaction resulting in skin change resembling a patch of scleroderma? 
Select and explain. 
A. Intramuscular injection of vitamin K preparations, B. Intramuscular injection of thiamine preparations, C. Intramuscular injection of cyanocobalamine preparations, D. Intramuscular injection of calcium preparations
A: Intramuscular injection of vitamin K preparations
Answer: A: Intramuscular injection of vitamin K preparations 
Explanation: Sclerodermiform reaction to vitamin K Intramuscular injection Vit. K is followed by an erythematous plaque in the lumbosacral area, which takes on a dusky colour and becomes infiltrated and itchy after 10-15 days. After some months, it resembles a patch of scleroderma, ivory-white in colour with a surrounding lilac ring. Confluence of plaques in the trochanteric and lumbosacral area produces the so- called 'cowboy's belt' appearance, complete with holsters.