This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Vaccination schedule, Subject name: Pediatrics
Vaccines that must be given before age of two years according to IAP are all of the following EXCEPT? 
Select and explain. 
A. Varicella vaccine, B. MMR vaccine, C. Conjugated typhoid vaccine, D. Pneumococcal polysaccharide vaccine
D: Pneumococcal polysaccharide vaccine
Answer: D: Pneumococcal polysaccharide vaccine 
Explanation: Vaccine Recommended age of vaccination (1st dose) a. Varicella vaccine 15 months b. MMR vaccine 9 months c. Conjugated typhoid vaccine 9 months d. Pneumococcal polysaccharide vaccine Beyond 2 yrs age - As polysaccharides stimulate B-cells independent of T-cells, the pneumococcal polysaccharide is poorly immunogenic at <2yrs age & immunological memory is low - Hence, it is recommended beyond 2yrs of age.