This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: FMGE 2019, Subject name: Pharmacology
Mechanism of action of exenatide in diabetes mellitus is 
Select and explain. 
A. It is analogue of GLP released from gut and increase glucose dependant insulin secretion, B. It is DPP-4 inhibitor and result in decreased breakdown of GLP, C. It inhibits SGLT-2 and cause glucosuria, D. It is amylin analogue and decrease glucagon
A: It is analogue of GLP released from gut and increase glucose dependant insulin secretion
Answer: A: It is analogue of GLP released from gut and increase glucose dependant insulin secretion 
Explanation: Exenatide is a Glucagon like peptide analogue which is approved as an injectable, adjunctive therapy in persons with type 2 DM Saxagliptin -> DPP4 inhibitor which inhibit the metabolism of GLP-1, therefore increase insulin. Canagliflozin, Dapagliflozin, Empagliflozin, Eugliflozin etc. Drugs-inhibit SGLT-2 -Inhibit glucose reabsorption, -result in glucosuria Pramlintide - amylin analogue - Given subcutaneously