This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
Th 1 type of cells are most dependent on - 
Select and explain. 
A. IFN-y, B. IL-4, C. IL-5, D. IL-6
A: IFN-y
Answer: A: IFN-y 
Explanation: Ananthanarayanan and Paniker's textbook of microbiology 9th edition . TH1 cells which produce cytokines , INF Gamma and IL2, which activate macrophage and T cells promoting cell mediated immunity, destruction of the target cells and killing of intracellular pathogens. .