This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General anatomy, Subject name: Anatomy
I time required to reach the steady state after a dosage regimen depends on 
Select and explain. 
A. Route of Administration, B. Half life of drug, C. Dose interval, D. Dosage of the drug
B: Half life of drug
Answer: B: Half life of drug 
Explanation: after a dosage regimen, concentraton of the drug to reach the stead state (when the eliminaton balances the input) is called steady state plasma concentration cpss cpss is reached in about 4-5 half lives. the amplitule fluctuations in Cpss depends on the dose interal relative t1/2 Ref-KDT 6/e p32