This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Which of the following is not associated with malignancy - 
Select and explain. 
A. Fragile X syndrome, B. Fanconi's syndrome, C. Down's syndrome, D. Bloom syndrome
A: Fragile X syndrome
Answer: A: Fragile X syndrome 
Explanation: Down syndrome is associated with incrased risk of leukemia. _____ Harrison