This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Antitubercular drug which DOES NOT cross blood-brain barrier is : 
Select and explain. 
A. Streptomycin, B. INH, C. Rifampicin, D. Pyrazinamide
A: Streptomycin
Answer: A: Streptomycin 
Explanation: Streptomycin and ethambutol do not cross blood-brain barrier whereas INH and pyrazinamide have maximum CNS penetration.