This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Social & Preventive Medicine
Drug that can be safely used in first trimester of pregnancy for treatment of malaria is: 
Select and explain. 
A. Quinine, B. Aemether, C. Both of the above, D. None of the above
A: Quinine
Answer: A: Quinine 
Explanation: According to current WHO guidelines, ACT (Aemesin combination therapy)s can be given in the second and third trimester of pregnancy. The recommended treatment in the first trimester of pregnancy is quinine. Ref: