This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
In acute solid organ Graft vs host disease, which of the following is not seen? 
Select and explain. 
A. Occurs within 100 days of transplantation, B. Skin is the most common organ involved, C. Preformed antibodies are involved, D. May lead to cholestatic jaundice
C: Preformed antibodies are involved
Answer: C: Preformed antibodies are involved 
Explanation: Answer- C. Preformed antibodies are involvedPreformed antibodies are involved in hyperacute rejection not in GVHD.Acute GVHD occvs within 100 days (usually 10-50 days) of bone marrow transplantation.