This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
Miladevi is a diagnosed case of ectopic gestation, which of the following will be the most reliable indicator: 
Select and explain. 
A. Arias stella reaction, B. Culdocentesis showing blood in the posterior cul-de-sac, C. Absence of the normal doubling of HCG levels, D. No gestational sac in USG
D: No gestational sac in USG
Answer: D: No gestational sac in USG 
Explanation: None