This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Mechanism of action of azoles is 
Select and explain. 
A. By altering membrane permeability, B. By blocking nucleic acid synthesis, C. By disrupting microtubules function, D. By inhibiting cell wall synthesis
A: By altering membrane permeability
Answer: A: By altering membrane permeability 
Explanation: According to the mechanism of action these can be classified as 

Drugs altering membrane permeability 

- Azoles 
- Triazoles e.g. Fluconazole, itraconazole, voriconazole, terconazole, posaconazole.
- Imidazoles e.g. Ketoconazole, miconazole, clotrimazole, econazole, butoconazole, oxiconazole, sertaconazole, sulconazole. 
- Terbinafine, butenafine, naftifine.
- Polyenes e.g. Amphotericin B, nystatin, hamycin 

Drugs blocking nucleic acid synthesis e.g. Flucytosine 
Drugs disrupting microtubule function e.g. Griseofulvin 
Drugs inhibiting cell wall synthesis e.g. Caspofungin, nikkomycin.