This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Disorders of Adrenal Gland, Subject name: Medicine
Which is the best treatment for management of malignant pheochromocytoma? 
Select and explain. 
A. Alpha blockers, B. Chemotherapy, C. Bulk reducing surgery, D. I131-MIBG
D: I131-MIBG
Answer: D: I131-MIBG 
Explanation: The first line choice for management of malignant pheochromocytoma is I131- MIBG at monthly intervals over three to six cycles. This is followed by Averbuch Chemotherapy protocol including dacarbazine, cyclophosphamide and vincristine.