This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: FMGE 2018, Subject name: Surgery
Best treatment strategy for carcinoma anal canal: 
Select and explain. 
A. Chemoradiation, B. Surgery, C. Radiation, D. Chemotherapy
A: Chemoradiation
Answer: A: Chemoradiation 
Explanation: Nowadays the primary treatment of choice is chemoradiotherapy (Combined modality therapy (CMT); Nigro Regimen), which usually includes 5-FU, Mitomycin-C and cisplatin Radical surgery is indicated in those with persistent or recurrent disease following CMT or Nigro Regimen.