This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immune system, Subject name: Medicine
Acute and recurrent pancreatitis is repoed to occur in 
Select and explain. 
A. Homocystinuria, B. Maple syrup urine disorder, C. Isovaleric acidemia, D. Tyrosinemia
C: Isovaleric acidemia
Answer: C: Isovaleric acidemia 
Explanation: Recurrent acute pancreatic attacks is a rare clinical condition (2-5% of all acute pancreatis) in children and is mainly idiopathic in most cases. Sometimes it may be associated with congenital anomalies, metabolic diseases or hereditary conditions. Isovaleric acidemia (IVA) is a rare autosomal recessive amino acid metabolism disorder associated with isovaleryl coenzyme A dehydrogenase deficiency presenting the clinical findings such metabolic acidosis with increased anion gap, hyperammonemia, ketonemia, hypoglycemia, "the odor of sweaty feet," abdominal pain, vomiting, feeding intolerance, shock and coma. Recurrent acute pancreatitis associated with IVA have been rarely repoed . Ref Davidson 23rd edition pg 1151