This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Psychiatry
Rett's syndrome is characterized by all except: 
Select and explain. 
A. Regression of acquired sills, B. Breath holding spells, C. Autistic behavior, D. Macrocephaly
D: Macrocephaly
Answer: D: Macrocephaly 
Explanation: Rett's syndrome Rett's syndrome is a rare developmental disorder of females which bears more resemblance to a neurodegenerative disorder than a psychiatric condition * Till 5-month development is normal Microcephaly Loss of acquired hand function and speech The loss of purposeful hand movements are replaced by stereotypic motions such ashand wringing Poorly coordinated gait and ataxia * Breathing problems--hyperventilation, breath holding, and sighing--are common, and help to distinguish Rett's from autism.