This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Dental
The main cytokine, involved in erythema nodosum leprosum (ENL) reaction is – 
Select and explain. 
A. Interleulcin – 2, B. Interferon – gamma, C. Tumor necrosis factor – alpha, D. Macrophage colony stimulating factor
C: Tumor necrosis factor – alpha
Answer: C: Tumor necrosis factor – alpha 
Explanation: Most important cytokine for Type II lepra reaction (ENL) is tumor necrosis factor (TNF- α).