This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Urethra & Penis, Subject name: Surgery
A 50-year-old male presents with hematuria. He is diagnosed of having bladder cancer which extends muscle deep. The best treatment: 
Select and explain. 
A. Intra vesical chemotherapy, B. Neoadjuvant chemotherapy followed by radical cystectomy, C. Radiotherapy, D. Transurethral resection
B: Neoadjuvant chemotherapy followed by radical cystectomy
Answer: B: Neoadjuvant chemotherapy followed by radical cystectomy 
Explanation: Ans. (b) Neoadjuvant chemotherapy followed by radical cystectomyRef: Bailey 26th Edition, Page 1335* Neoadjuvant chemotherapy improves survival by about 5 -7 %. Radical cystectomy is the standard treatment for muscle invasive bladder cancer.