This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Bacterial infection, Subject name: Medicine
Which of the following is FALSE about Infectious mononucleosis 
Select and explain. 
A. Non-Suppurative, painless Lymphadenopathy, B. Maculo-papular rash or petechial rash, C. Lymphocytosis is usually demonstrable, with >10% atypical lymphocytes, D. Transient bilateral upper lid Edema
A: Non-Suppurative, painless Lymphadenopathy
Answer: A: Non-Suppurative, painless Lymphadenopathy 
Explanation: Atypical lymphocytosis -points diagnosis towards Infectious mononucleosis (EBV) (kissing disease) among the given other options. Essentials of Diagnosis Malaise, fever, and (exudative) sore throat Palatal petechiae, lymphadenopathy, splenomegaly, and, occasionally, a maculopapular rash Positive heterophile agglutination test (Monospot) Atypical large lymphocytes in blood smear; lymphocytosis Complications:hepatitis, myocarditis, neuropathy, encephalitis, airway obstruction from adenitis, hemolytic anemia, thrombocytopenia General Consideration EBV is ubiquitous; infects > 95% of the adult population worldwide and persists for the person's lifetime Infectious mononucleosis is a common manifestation of EBV and may occur at any age EBV is largely transmitted by saliva but can also be recovered from genital secretions Saliva may remain infectious during convalescence, for 6 months or longer after symptom onset The incubation period lasts several weeks (30-50 days) In the United States the incidence of EBV infection is declining although prevalence of EBV remains high for those aged 12-19 years Clinical Findings Symptoms and Signs Fever, sore throat, fatigue, malaise, anorexia, and myalgia typically occur in the early phase of the illness Physical findings include Lymphadenopathy (discrete, nonsuppurative, slightly painful, especially along the posterior cervical chain) Transient bilateral upper lid edema (Hoagland sign) Splenomegaly (in up to 50% of patients and sometimes massive) Conjunctival hemorrhage, exudative pharyngitis, uvular edema, tonsillitis, or gingivitis may occur Soft palatal petechiae may be noted Other manifestations Hepatitis Interstitial pneumonitis (sometimes with pleural involvement) Cholestasis Gastritis Kidney disease (mostly interstitial nephritis) Epiglottitis Nervous system involvement (in 1-5%)