This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
Acquire IgA deficiency may occur in ? 
Select and explain. 
A. Severe Congenital toxoplasmosis, B. Severe Measles infection, C. Severe Brucellosis, D. Severe Leptospirosis
A: Severe Congenital toxoplasmosis
Answer: A: Severe Congenital toxoplasmosis 
Explanation: Severe Congenital toxoplasmosis Block in B cell differentiation due to defective interaction between T and B cells. Naive B cells are not able to differentiate into IgA - producing cells.