This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Carbohydrates, Subject name: Biochemistry
A genetic disorder renders fructose 1,6 -- bisphosphates in liver less sensitive to regulation by fructose 2,6 -- bi-phosphate. All of the following metabolic changes are observed in this disorder except: 
Select and explain. 
A. Level of fructose 1,6--biphosphate is higher than normal, B. Level of fructose 1,6 -- biphosphate is lower than normal, C. Less pyruvate is formed, D. Less ATP is formed
A: Level of fructose 1,6--biphosphate is higher than normal
Answer: A: Level of fructose 1,6--biphosphate is higher than normal 
Explanation: Ans. A. Level of fructose 1,6--biphosphate is higher than normalFructose 2,6 - biphosphate acts to decrease the activity of fructose 1,6 - bisphosphates. When the enzyme becomes less sensitive to regulation, the inhibitory effect is lost and the enzyme activity increases. The following effects are observed:a. Level of fructose 1,6 -- biphosphate decreasesb. Pyruvate is used up for glucose synthesisc. ATP is used up for glucose synthesis