This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Coarctation of Aoa is most commonly associated with which of the following structural defects? 
Select and explain. 
A. Patent Ductus Aeriosus (PDA), B. Ventricular Septal Defect (VSD), C. Atrial Septal Defect (ASD), D. Bicuspid Aoic valve
D: Bicuspid Aoic valve
Answer: D: Bicuspid Aoic valve 
Explanation: Coarctation of Aoa is associated with Bicuspid Aoic Valve in 40% of patients. Clinical manifestations of coarctation depend on site & extent of obstruction and the presence of associated cardiac anomalies, most commonly a bicuspid aoic valve. Ref: Current Surgical 12th Edition, Page 426; Harrison's 16th Edition, Page 1387.