This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
The  most  general  term  for  the  process  by  which  the amount  of  active  drug  in  the  body  is  reduced  after absorption into the systemic circulation is: 
Select and explain. 
A. Excretion, B. Elimination, C. First pass metabolism, D. Distribution
B: Elimination
Answer: B: Elimination 
Explanation: Drug elimination is the sum total of metabolic inactivation and excretion.
Depending upon the ability of the body to eliminate a drug, a certain fraction of the central compartment may be considered, to be totally 'cleared' of that drug in a given period of time to account for elimination over that period.
 
Reference: Essentials of Medical Pharmacology Eighth Edition KD TRIPATHI page no 38