This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Which of the following thiazide can be used in severe renal failure? 
Select and explain. 
A. Chlorthiazide, B. Metolazone, C. Trichloromethazide, D. Bendroflumethiazide
B: Metolazone
Answer: B: Metolazone 
Explanation: Thiazide diuretics can't be used in severe renal failure cases as they alter GFR. But Metolazone and Indapamide are the exceptions.