This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Parasitology Pa 1 (Protozoology), Subject name: Microbiology
Romana sign is seen in? 
Select and explain. 
A. Chaga's disease, B. Kala Azar, C. Sleeping sickness, D. Fasciola
A: Chaga's disease
Answer: A: Chaga's disease 
Explanation: Romana's sign is the classic finding in acute Chagas disease, which consists of unilateral painless edema of the palpebrae and periocular tissues. It can result when the conjunctiva is the poal of entry of T.cruzi