This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Treatment, Subject name: Psychiatry
Clozapine is used in: 
Select and explain. 
A. Depression, B. Resistant schizophrenia, C. Mania, D. Delirium
B: Resistant schizophrenia
Answer: B: Resistant schizophrenia 
Explanation: Ans: b (Resistant schizophrenia) Ref: Katzung, 10th ed, p. 457Clozapine is an atypical antipsychotic. It has weak D2 blocking action and produces few extrapyramidal side effects.lt inhibits 5-HT, receptor.The main adverse effects are agranulocytosis and other blood dyscrasias. It reduces seizure threshold. It is reserved for resistant cases of schizophrenia.