This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: First-Trimester Spontaneous Abortion, Subject name: Gynaecology & Obstetrics
Most common cause of spontaneous abortion is? 
Select and explain. 
A. Chromosomal abnormality, B. Uterine malformations, C. Immunological, D. Infections
A: Chromosomal abnormality
Answer: A: Chromosomal abnormality 
Explanation: ANSWER: (A) Chromosomal abnormalityREF: Dutta 6th ed p. 159Most common cause of spontaneous abortion is chromosomal abnormality, trisomy of chromosome 16.