This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
All of the following statements about Leptospirosis are true, except: 
Select and explain. 
A. Infection acquired by direct contact with infected urine, B. Moality is 5-15% in severe cases, C. Antibodies are usually detectable in the first week, D. IV penicillin is recommended for treatment of severe cases
C: Antibodies are usually detectable in the first week
Answer: C: Antibodies are usually detectable in the first week 
Explanation: Antibodies are usually detectable from 12th day of disease and peaks level is seen by the 3rd week. Low titres will be present for years. Ref: Kliegman, Behrman, Jenson, Stanton (2008), "Nelson textbook of Pediatrics", Chapter 217, "Leptospira", Volume 1, Page 1272; Textbook of Microbiology by Ananthnarayan, 7th Edition, Page 392; Park's Social and Preventive Medicine , 20th Edition, Page 7255; Harrison's Principles of Internal Medicine, 17th Edition, Pages 1050-51