This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Major contribution towards gluconeogenesis is by: 
Select and explain. 
A. Lactate, B. Glutamate, C. Ketones, D. Alanine
A: Lactate
Answer: A: Lactate 
Explanation: The synthesis of glucose from noncarbohydrate compounds is known as gluconeogenesis. The major substrates/precursors for gluconeogenesis are lactate, pyruvate, glucogenic amino acids, propionate and glycerol.
Satyanarayana Pg No: 258