This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
In pemphigus, autoantibodies are directed against which of the following structures? 
Select and explain. 
A. Acetylcholine receptor, B. Sarcomere, C. Epidermis, D. Thyroid follicle
C: Epidermis
Answer: C: Epidermis 
Explanation: Pemphigus is an autoimmune disease wherein autoantibodies against epidermis cells are produced. Histologically, a phenomenon called acantholysis, wherein epidermal cells appear to detach and separate from each other, is observed.