This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: NEET 2019, Subject name: Biochemistry
Which of the following is not the source of cytosolic NADPH:- 
Select and explain. 
A. Isocitrate dehydrogenase, B. ATP citrate lyase, C. Malic enzyme, D. G6PD
B: ATP citrate lyase
Answer: B: ATP citrate lyase 
Explanation: SOURCE of Cytosolic NADPH HMP pathway Malic enzyme Isocitrate dehydrogenase Main enzyme - G6PD alternative pathway to glycolysis and TCA cycle for the oxidation of glucose the main pathway for biosynthesis of NADPH and pentoses. Conves malate to pyruvate NADPH and CO2 are generated NADPH mainly utilized for fatty acid synthesis 3 isoenzymes One, which uses (NAD+) in Mitochondria other two use NADP+ in Mitochondria and cytosol