This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Anatomy
Histology of benign lesion is 
Select and explain. 
A. Well differentiated, B. Atypical, C. High mitotic figures, D. Locally invasive
A: Well differentiated
Answer: A: Well differentiated 
Explanation: CharacteristicsBenignMalignantDifferentiation Well differentiated; structure may be typical of tissue of origin Some lack of differentiation with anaplasia; the structure is often atypicalThe rate of growth Usually progressive & slow; may come to a standstill or regress; mitotic figures are rare & normal Erratic & may be slow to rapid; mitotic figures may be numerous & abnormal Local invasion Usually cohesive & expansile well-demarcated masses that do not invade or infiltrate surrounding normal tissuesLocally invasive, infiltrating the surrounding normal tissues; sometimes may be seemingly cohesive & expansile Metastasis Absent Present; the larger and more differentiated the primary, the more likely are metastases