This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Dose of which of the following may not be altered with deranged value of GFR - 
Select and explain. 
A. Cefepime, B. Cefoperazone, C. Cefuroxime, D. Tetracycline
B: Cefoperazone
Answer: B: Cefoperazone 
Explanation: Ans. is 'b' i.e., Cefoperazone o Cefoperazone, ceftriaxone and cefopiramide do not require dose reduction in renal failure.