This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pathology
Which is not a characteristic of wegeners granulomatosis? 
Select and explain. 
A. Granuloma in vessel wall, B. Focal necrotising glomerulonephritis, C. Positive for cANCA, D. Involves large vessels
D: Involves large vessels
Answer: D: Involves large vessels 
Explanation: Wegener granulomatosis is a necrotizing vasculitis characterizedby a specific triad of findings:* Granulomas of the lung and/or the upper respiratorytract (ear, nose, sinuses, throat)* Vasculitis of small to medium-sized vessels (capillaries,venules, aerioles, and aeries), most prominently inthe lungs and upper respiratory tract* GlomerulonephritisWegener granulomatosis is likely to be initiated as acell-mediated hypersensitivity response directed againstinhaled infectious or environmental antigens. PR3-ANCAsare present in almost 95% of cases and probably drive thesubsequent tissue injury.(Robbins basic pathology,9th edition,pg no.353)