This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
A female patient presented with depressed mood, loss of appetite and no interest in surroundings., There is associated insomnia. The onset of depression was preceeded by a history of business loss and soon after it she developed the following symptoms for the past one year. True statement regarding management  patient is? 
Select and explain. 
A. No treatment is necessary as it is due to business loss, B. SSRI is the most efficacious of the available drugs, C. Start SSRI treatment based on side effect profile, D. Combination therapy of 2 anti-depressant drugs
C: Start SSRI treatment based on side effect profile
Answer: C: Start SSRI treatment based on side effect profile 
Explanation: None