This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetic and genetic disorders, Subject name: Pediatrics
Neurofibromatosis 1 criteria include all except: 
Select and explain. 
A. Brain tumor, B. Acoustic neuromas, C. Dysplasia of the sphenoidal and tibial bone, D. Cafe-au-lait spots
B: Acoustic neuromas
Answer: B: Acoustic neuromas 
Explanation: In Neurofibromatosis 1 (NF1), two or more of the following clinical manifestations are present: Six or more Cafe-au-lait macules Axillary and inguinal freckling Two or more iris Lisch nodules Two or more neurofibromas or 1 plexiform neurofibroma A distinctive osseous lesion such as sphenoidal and tibial dysplasia Optic gliomas A 1st degree relative with NF1 Ref: Nelson textbook of pediatrics 21st edition pgno: 3141