This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of lipid, Subject name: Biochemistry
The APO-B100 and APO-B48 are different lipoproteins due to 
Select and explain. 
A. DNA duplication, B. RNA splicing, C. RNA editing, D. Misreading of m-RNA
C: RNA editing
Answer: C: RNA editing 
Explanation: Apo-B100,one of the largest proteins is a longer version of Apo-B48 Both Apo B proteins are encoded by same gene and produced from same initial RNA transcript. Apo-B48 lacking the LDL receptor binding domain,is generated by this post transcriptional change in m-RNA sequence Reference: Harpers illustrated biochemistry 30th edition