This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetics And Genetic Disorders, Subject name: Pediatrics
Which of the following is the most likely inheritance pattern in the pedigree given below? 
Select and explain. 
A. Autosomal dominant, B. Mitochondrial, C. Autosomal recessive, D. X-linked dominant
D: X-linked dominant
Answer: D: X-linked dominant 
Explanation: d. X-linked dominant(Ref: Nelson's 20/e p 593, Ghai 8/e p 641)It is an X-linked dominant pattern of inheritance, all the female offsprings of a diseased male (XY) receive abnormal X chromosome & express the disease, whereas none of the male offsprings of diseased father have the disease.