This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
Macrophages are conveed to epitheloid cells by which cytokine- 
Select and explain. 
A. IL-2, B. IFN-y, C. TNF-a, D. TGF-b
B: IFN-y
Answer: B: IFN-y 
Explanation: Ref Robbins 9)e p46 IL 1and 2 stimulate proliferation of more T cells. Interferon gamma activated macrophages. TNF alpha promoters fibroblasts proliferation and activates endothelium to secreted PGs which have a role in vascular response in inflammation. TGF Beta and PDGF elaborated by the macrophages stimulate fibroblast growth. .