This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous (Neoplasia), Subject name: Surgery
HIV positive patients present with the following appearance of the leg with a history of HHV-8 infection, what is the most likely diagnosis? 
Select and explain. 
A. Lymphoma, B. Kaposi sarcoma, C. Malignant melanoma, D. Non-Hodgkin's lymphoma
B: Kaposi sarcoma
Answer: B: Kaposi sarcoma 
Explanation: Ans. (b) Kaposi sarcoma.Kaposi's sarcoma (KS) is a soft tissue sarcoma of vascular origin that is induced by the human herpes virus 8. The incidence of KS increased dramatically during the AIDS epidemic.Image source- style="font-family: Times New Roman, Times, serif">