This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General, Subject name: Medicine
First centre that get activated before skilled voluntary movements is? 
Select and explain. 
A. Neo cortex, B. Hypothalamus, C. Pons, D. Medulla
A: Neo cortex
Answer: A: Neo cortex 
Explanation: ANSWER: (A) Neo cortexREF: Ganong's 22nd edition page 203Repeat from June 2011"The lateral corticospinal tract is concerned with skilled movements"See APPENDIX-15 for detailsOrigin: primary motor cortex (30%), premotor and supplementary motor area (30%) and somatosensory areas posterior to central sulcus (40%)It passes through posterior limb ofg internal capsule and then forms the pyramid of medulla Lateral corticospinal tractVentral corticospinal tract* 80% fibres cross in medulla to opposite side to form lateral corticospinal tract* Concerned with skilled movements and end directly on motor neurons in humans* Uncrossed fibres form ventral corticospinal tract* Don't cross until it reaches level of musclesGiant cells of betz are the originating cells of the tract located in primary motor cortex.