This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti Microbial, Subject name: Pharmacology
All are false about tigecycline, except: 
Select and explain. 
A. Dose reduction in renal failure, B. 90% pseudomonas strains are sensitive, C. Oral and parenteral bioavailability is same, D. Not preferred in UTI
D: Not preferred in UTI
Answer: D: Not preferred in UTI 
Explanation: Ans. d. Not preferred in UTIRef: Goodman Gilman 12th e/P 1523Tigecycline, doxycycline and minocycline are safe in renal failure.Tigecycline is active against gram negatives with the exception of pseudomonas, providencia, morganella and proteus.Tigecycline has poor bioavailability and hence is given only by parenteral route.Tigecycline is poorly concentrated in urine and hence should be avoided in treatment of urinary tract infection.