This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Medical Illness Complicating Pregnancy, Subject name: Gynaecology & Obstetrics
Fetus was found to have a congenital hea block (CHB), what should be evaluated in the mother? 
Select and explain. 
A. SLE, B. APLA, C. Diabetes mellitus, D. Haemolytic anemia
A: SLE
Answer: A: SLE 
Explanation: SLE is Pregnancy- SLE - causes - multi organ damage in the mother and antibodies against the antigens blood circulation enter the fetus causing multiple problems to the fetus mainly congenital hea block CHB is the most serious complication of neonatal lupus erythematosus. Transplacental transfer of maternal anti - SSA/RO or anti- SSB/LA antibodies is associated with development of CHB. CHB is mostly diagnosed between 18 -24th weeks of gestation.