This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: miscellaneous, Subject name: Pathology
Werner disease is associated with?- 
Select and explain. 
A. Intestinal polyps, B. Multiple cancer, C. Lax joints, D. Premature ageing
D: Premature ageing
Answer: D: Premature ageing 
Explanation: DNA repair mechanisms are defective in diseases such as Werner syndrome and ataxia-telangiectasia. Werner syndrome (WS), also known as "adult progeria", is a rare, autosomal recessive disorder which is characterized by the appearance of premature aging. Werner syndrome is named after the German scientist Otto Werner.