This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Infection, Subject name: Medicine
Treatment with what antibiotic is most likely to have resulted in this patient's skin changes? 
Select and explain. 
A. Rifampin, B. Chloramphenicol, C. Nitrofurantoin, D. Minocycline
D: Minocycline
Answer: D: Minocycline 
Explanation: Answer D. MinocyclineMinocycline was the cause of this patient's hyperpigmentation.