This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: NSAIDs, Gout and Rheumatoid Ahritis, Subject name: Pharmacology
Which of the following drugs reduces the activity of phospholipase A2? 
Select and explain. 
A. Alprostadil, B. Aspirin, C. Ibuprofen, D. Prednisolone
D: Prednisolone
Answer: D: Prednisolone 
Explanation: Prednisolone: It is a powerful anti-inflammatory agent. It acts by inhibiting the synthesis of PG, TX and LT the inhibition of phospholipase A2 enzyme. It is most impoant mechanism of anti-inflammatory action is the inhibition of chemotaxis.