This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
A child died soon after bih. On examination there was hepatosplenomegaly and edema all over body. Most probable diagnosis in - 
Select and explain. 
A. b-thalassemia, B. a-thalassemia, C. Hereditary spherocytosis, D. ABO incompatibility/sickle cell anemia
B: a-thalassemia
Answer: B: a-thalassemia 
Explanation: Ans. is 'b' i.e., alpha-thalassemia o Out of the given 4 types of hemolytic anemias only alpha thalassemia is able to give rise to such severe presentation at bih. In all other conditions the newborn is either normal or has mild jaundice.