This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Diagnosis of Pregnancy, Subject name: Gynaecology & Obstetrics
All of the following are biochemical markers included for triple test except: 
Select and explain. 
A. Alfa feto protein (AFP), B. Human chorionic gonadotropin (HCG), C. Human Placental Lactogen (HPL), D. Unconjugated oestriol
C: Human Placental Lactogen (HPL)
Answer: C: Human Placental Lactogen (HPL) 
Explanation: Dual test - Upto 12 weeks : PAPP-A and hCG : NT > 3mm , High hCG and Low PAPP-A are suggestive of Trisomy Triple test - from 16th week onwards : MSAFP, hCG , uE3 : High hCG, Low MSAFP and Low uE3 are suggestive of Trisomy Quadruple (Quad) test - MSAFP, hCG , uE3, inhibin: In addition to Triple test, Inhibin A higher than normal is suggestive of Trisomy