This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
Most severely affected child in Rh-isoimmunisation patients : 
Select and explain. 
A. Rh negative mother with Rh positive in 2nd child, B. Rh positive mother with Rh negative in 2nd child Rh positive mother with Rh negative in 15' child, C. Rh positive mother with Rh negative in 15' child, D. Rh positive mother with Rh positive in 2"'d child
A: Rh negative mother with Rh positive in 2nd child
Answer: A: Rh negative mother with Rh positive in 2nd child 
Explanation: Rh negative mother with Rh positive in 2nd child