This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Bleeding and Thrombotic Disorders, Subject name: Medicine
Which of the foliowingmay present with isolated prolongation of prothrombin time (PI> 
Select and explain. 
A. Factor VIiI deficiency, B. FActor VII deficiency, C. Factor XII deficiency, D. Factor IX deficiency
B: FActor VII deficiency
Answer: B: FActor VII deficiency 
Explanation: Ans. is 'b' i.e., Factor VII deficiency o Factor VII deficiency may present with isolated prolongation of prothrombin time.Cause of Isolated prolongation of PT (CMDT)# Vitamin K deficiency# Warfarin therapy# Liver disease# Factor VII deficiency