This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology and breast, Subject name: Surgery
A female presents with ductal ca in situ of breast with diffuse microcalcifications on mammography. She also gives family history of breast ca. What is best possible management 
Select and explain. 
A. Breast conservative surgery, B. Simple mastectomy, C. Modified radical mastectomy, D. Radiotherapy
B: Simple mastectomy
Answer: B: Simple mastectomy 
Explanation: .* Total (simple) mastectomy: Along with the tumour, entire breast, areola, nipple, skin over the breast, including axillary tail are removed. There is no axillary dissection. Often the patient is subjected to radiotherapy later (External) to axilla. * Conservative breast surgeries: Tumour is removed with a rim of 1 cm of normal tissue. It may be a. Wide excision. b. Quadrantectomy as pa of therapy -- QUA (VERONESI): Entire segment of the involved breast is removed along with axillary dissection (done through a separate incision in the axilla, level I and II removal) and radiotherapy. There is a higher rate of local recurrence after conservative QUA therapy especially in younger patient and in high grade tumours. ref:SRB&;s manual of surgery,ed 3,pg no 484