This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Physiological Changes of Pregnancy, Subject name: Gynaecology & Obstetrics
All of these are physiological changes in pregnancy except? 
Select and explain. 
A. Increase in blood volume by 30-40%, B. Serum fibrinogen increases by 50%, C. Increase in platelet count, D. Decrease in packed cell volume
C: Increase in platelet count
Answer: C: Increase in platelet count 
Explanation: There is decrease in platelet counts in pregnancy which is also known as gestational thrombocytopenia Lower platelet concentrations are paially due to hemodilution Platelet consumption is likely augmented because of splenic enlargement There may be an element of "hypersplenism," in which platelets are prematurely destroyed