This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.N.S, Subject name: Pharmacology
Which antiepileptic drug leads to gingival hyperplasia: 
Select and explain. 
A. Phenytoin, B. Carbamazepine, C. Valproate, D. Lamotrigine
A: Phenytoin
Answer: A: Phenytoin 
Explanation: Ans. A. PhenytoinPhenytoin causes gingival hyperplasia, hirsutism, megaloblastic anemia, osteomalacia. Carbamazepine causes agranulocytosis, valproate is hepatotoxic and also causes spina bifida. Lamotrigine is known to cause Steven Johnson syndrome.