This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Pathology
Deficiency of lysyl hydroxylase causes? 
Select and explain. 
A. Alpo syndrome, B. Menkes disease, C. Epidermolysis bullosa, D. Osteogenesis imperfecta
B: Menkes disease
Answer: B: Menkes disease 
Explanation: Alpo syndrome is caused by mutation in the collagen genes COL4A3 and COL4A6.Epidermolysis bullosa dystrophica is due to mutation in the collagen gene COL7A1.Osteogenesis imperfecta is caused by mutations in COL1A1 and COL1A2