This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Psychiatry
Which of the following drug if given along with serotonergic drugs can lead to Serotonin syndrome ? 
Select and explain. 
A. Buspirone, B. Fluoxetine, C. Penfluridol, D. Clozapine
B: Fluoxetine
Answer: B: Fluoxetine 
Explanation: Co - prescription of serotonergic drugs with other serotonergic agents especially MAOIs can lead to serotonin syndrome. It is characterised by classic triad of mental status changes, neuromuscular abnormalities and autonomic hyperactivity. These include anxiety, agitation, confusion, clonus, hyperreflexia, myoclonus, rigidity, increased heart rate, tremor, flushing, hyperthermia and excessive sweating.
Death can occur in severe serotonin syndrome.