This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Transcription, Subject name: Biochemistry
Which of the following statement is TRUE about iron response element? 
Select and explain. 
A. Stem loop structure in the messenger RNA, B. Located at the 5' untranslated region(UTR) of transferrin mRNA, C. Located at the 3' untranslated region(UTR) of ferritin mRNA, D. IRE-binding protein causes degradation of IRE
A: Stem loop structure in the messenger RNA
Answer: A: Stem loop structure in the messenger RNA 
Explanation: mRNAs of ferritin and tfR 1 contain a stem-loop structure known as Iron Response Element (IRE). IRE of ferritin mRNA is located at its 5' UTR. (Ferritin ->Five) - option c is wrong IRE of transferrin receptor is located at its 3'UTR. (TfR ->Three) - option b s wrong. IRP-IRE interaction prevents the translation of ferritin mRNA. IRP-IRE interaction stabilises the mRNA of transferrin receptor-more intracellular iron absorption.- option d is wrong.