This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Pharmacology
All of the following are indications for postoperative radiotherapy in a case of Carcinoma Endometrium except not related - surgery 
Select and explain. 
A. Myometrial invasion >1/2 thickness, B. Positive lymph nodes, C. Endocervical involvement, D. Tumour positive for estrogen receptors
D: Tumour positive for estrogen receptors
Answer: D: Tumour positive for estrogen receptors 
Explanation: As far as receptor status is concerned, the best correlation is that of a good prognosis with high progesterone receptors rather than a poor prognosis with high estrogen receptors. The best prognostic factor of cancer endometrium, amongst others, is the Histological grading of the diseaseOther impoant predictors are:* Depth of myometrial invasion * Status of pelvic and para-aoic lymph nodes* Malignant cells in peritoneal washings * Lymph-vascular invasion* Cervical invasion