This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
Defects in Enterohepatic Circulation of Bile Acids due to the altered canalicular function is seen in: 
Select and explain. 
A. Cirrhosis, B. Primary biliary cirrhosis, C. Gilbe's syndrome, D. Dubin johnson syndrome
B: Primary biliary cirrhosis
Answer: B: Primary biliary cirrhosis 
Explanation: Defects in Enterohepatic Circulation of Bile Acids Decreased Bile acid synthesis is affected in Cirrhosis decreased Biliary secretion due to Altered canalicular function Primary biliary cirrhosis Ref: Harrison, E-18, P-2462.