This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Blood Vessels, Subject name: Pathology
c-ANCA is positive in 
Select and explain. 
A. Microscopic Polyangitis, B. Wegener's Granulomatosis, C. Churg Strauss Syndrome, D. Behcet's syndrome
B: Wegener's Granulomatosis
Answer: B: Wegener's Granulomatosis 
Explanation: Ans. (b) Wegener's Granulomatosis(Ref: Robbins 9th/pg 507, Harrison 18thed p-2786-87)C-ANCA (proteinsase 3 Q is the target antigen)Typically seen in Wegner's Granulomatosis Q