This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Which of the following physical signs is seen in a patient with severe aoic stenosis: 
Select and explain. 
A. Opening snap, B. Diastolic rumble, C. Holosystolic murmur, D. Delayed peak of systolic murmur
D: Delayed peak of systolic murmur
Answer: D: Delayed peak of systolic murmur 
Explanation: Answer is D (Delayed peak of systolic murmur) The ejection systolic murmur stas after the ejection click reaches a peak in midsystole. With increasing severity of aoic stenosis the peak gets delayed so that the maximum intensity of the murmur is closer to the end rather than being midsystolic.