This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Venoocclusive disease of the liver is caused by: 
Select and explain. 
A. Cyclophosphamide, B. Melphalan, C. Both, D. None
C: Both
Answer: C: Both 
Explanation: Potential target for sinusoidal lining cells; when these are injured, such as by high-dose chemotherapeutic agents (e.g., cyclophosphamide, melphalan, busulfan) administered prior to bone marrow transplantation, venoocclusive disease can result. Reference: Harrisons Principles of Internal Medicine, 18th Edition, Page 2560