This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Which of these muscles undergoes wasting first in osteoahritis knee? 
Select and explain. 
A. Quadriceps only, B. Hamstrings only, C. Both quadriceps and Hamstrings, D. Gastronemius
A: Quadriceps only
Answer: A: Quadriceps only 
Explanation: All periaicular muscles around the knee joint may undergo wasting in advanced osteohritis knee. However muscle atrophy paicularly involves the quadriceps which is the earliest muscle to undergo wasting. Ref: Turek s Ohopaedics 2nd Edition, Page 1368.