This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Not true about polycystic kidney disease is - 
Select and explain. 
A. Autosomal dominant, B. Proteinuria <2gm/day, C. Leads to CRF, D. Decompression of cyst leads to normal renal function
D: Decompression of cyst leads to normal renal function
Answer: D: Decompression of cyst leads to normal renal function 
Explanation: Decompression or uncapping of cysts (Rovsings operation) is of no use in preserving the renal function.

Polycystic kidney disease 

Is of 2 types:

Adult PKD
Inheritance is AD
Disease manifests itself in adult life.
Infantile PKD
 Inheritance is AR
Disease manifests in infancy as severe renal failure and life expectancy is short.

Adult PKD

Almost always bilateral (95%)
Disease ordinarily does not manifest itself before 40 yr of age.
Pts. of APKD have increased frequency of cysts in liver (30%), Pancreas, Spleen"; ovaries & berry aneurysm of cerebral arteries.

Pathology -

the kidney is enlarged 3 to 4 times.
It is studded all over with cysts.
Cysts are distributed evenly throughout the cortex & medulla.
Content of the cyst varies but its not urine.
Renal tissue is progressively replaced by cysts leading to CRF.

Clinical Presentation

Mass
Pain
Hypertension (70 to 80% of cases)
Henzaturia
Infection
Uremia
Urine examination
high output of urine,
low specific gravity.
It may contain traces of albumin
It ultimately leads to CRF and renal transplantation is the only definite t/t.