This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Anatomy
All are true about typhoid ulcer except 
Select and explain. 
A. Mainly affects ileum, B. Multiple ulcer and transverse, C. Perforation occurs at 3rd wrek, D. Perforation treated by surgery
B: Multiple ulcer and transverse
Answer: B: Multiple ulcer and transverse 
Explanation: Refer Robbins page no Pg 9/e 789 Clinical features Classic features are fever, abdominal pain and hematochezia First week of illness: rising ("stepwise") fever associated with chills, although frank rigors are rare Also relative bradycardia or pulse-temperature dissociation is common Second week of illness: abdominal pain develops and "rose spots" (faint salmon- colored macules on the trunk and abdomen) may be seen Third week of illness: hepatosplenomegaly, intestinal bleeding and perforation due to ileocecal lymphatic hyperplasia of the Peyer's patches may occur, together with secondary bacteremia and peritonitis ( Perforation is four times more common in males than females (Chronic Salmonella carriage is defined as excretion of the organism in stool or urine >12 months after acute infection Diagnosis Classical clinical features above Typhoid fever is diagnosed by blood or stool culture Bone marrow culture is the most sensitive test available (<a class="bl" style="margin: 0px; padding: 0px; border: 0px; font-style: inherit; font-variant: inherit; font-weight: bold; font-stretch: inherit; font-size: 9pt; line-height: inherit; font-family: inherit; veical-align: baseline; color: ; overflow-wrap: break-word;" href=" 1975; 1:1211</a>), as it remains positive even after 5 days of antibiotic therapy.