This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
As a side effect the metabolic syndrome is most commonly associated with which of the following group of medications - 
Select and explain. 
A. Anti-anxiety drugs, B. Anti-depressant drugs, C. Anti-psychotic drugs, D. Anti-cholinergic drugs
C: Anti-psychotic drugs
Answer: C: Anti-psychotic drugs 
Explanation: Ans. is 'c' i.e., Anti-psychotic drugs Metabolic syndrome (svndrome-X1 o Metabolic syndrome is a combination of medical disorders that increase the risk of developing cardiovascular disorder and diabetes. o The components of metabolic syndrome are obesity, insulin resistance (resulting in high insulin level), elevated serum triglyceride and LDL, low HDL and hypeension. o Antipsychotics can cause weight gain, diabetes and metabolic syndrome. o Antipsychotics commonly implicated are clozapine, olanzapine, chlorpromazine and thioridazine.