This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Plastic Surgery and Skin Lesions, Subject name: Surgery
Which of the following insufflation gases should not be used with radiofrequency (RF) electrosurgery ? 
Select and explain. 
A. CO2, B. Nitrous oxide, C. Argon, D. Helium
B: Nitrous oxide
Answer: B: Nitrous oxide 
Explanation: CO2 is the most commonly used gas for peritoneal insufflation, but alternative gases are available. Nitrous oxide has been used for procedures performed under local anesthesia because it does not cause the acid-base disturbances associated with CO2 pneumoperitoneum and may cause less postoperative pain. However, it suppos combustion, and its use is not recommended in procedures that require RF electrosurgery. Use of ine gases, such as helium and argon, also prevents acid-base problems; however, these agents are rarely used because they are expensive and have low solubility, which may increase the risk for gas embolism.