This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Amino Acid Metabolic Disorder, Subject name: Biochemistry
Enzyme dificient in alkaptonuria - 
Select and explain. 
A. Kynureninase, B. Tyrosine hydroxylase, C. Homogentisate oxidase, D. Tyrosinase
C: Homogentisate oxidase
Answer: C: Homogentisate oxidase 
Explanation: Ans. is 'c' i.e., Homogentisate oxidase Metabolic diseaseEnzyme deficientMaple syrup urine diseaseBranched chain ketoacid dehydrogenaseMethyl-melonic aciduriaMethyl-malonyl CoA mutase (isomerase)Sweaty feet odor in bodyIsovaleryl-CoA dehydrogenaseTvrosinemia I (Tyrosinosis)Fumarylacetoacetate hydroxylaseTyrosinemia IITyrosine transaminase (Tyrosine aminotransferase)Neonatal tyrosinemiaHydroxyphenyl pyruvate hydroxylaseAlbinismTyrosinaseAlkaptonuriaHomogentisate oxidasePhenylketonuriaPhenylalanine hydroxylaseOrotic aciduriaOMP decarboxylaseHomocystinuriaCystathionine svnthataseLesh-Nyhan syndromeComplete deficiency of enzyme HGPRTCystinosisCystine reductase