This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General physiology, Subject name: Physiology
True about intracellular receptor 
Select and explain. 
A. Mainly on nuclear surface, B. Estrogen does not act on it, C. GH acts on it, D. Vitamin E act on these
A: Mainly on nuclear surface
Answer: A: Mainly on nuclear surface 
Explanation: Interacellular receptors are mainly present on nuclear surface They are eeceptors for peptide hormones Ref:Guyton and Hall textbook of medical physiology 12th edition,page number:540,541,542