This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
All of the following conditions cause an increase in AFP except? 
Select and explain. 
A. Hepatoblastoma, B. Multiple gestation, C. Increased maternal weight, D. Anterior abdominal defect
C: Increased maternal weight
Answer: C: Increased maternal weight 
Explanation: Decreased maternal weight is associated with an increase in AFP levels. Other causes of increased AFP levels are anencephaly, spina bifida, abdominal wall defects, renal anomalies, multiple pregnancy, IUFD and wrong gestational dates. Reference: Encyclopedia of Women's Health edited by Sana Loue, page 85.