This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Treatment in psychiatry, Subject name: Psychiatry
Which of the following increases on Electroconvulsive therapy 
Select and explain. 
A. 5-hydroxy-indole-acetic acid, B. Dopamine, C. Serotonin, D. Brain derived neurotrophic factor
D: Brain derived neurotrophic factor
Answer: D: Brain derived neurotrophic factor 
Explanation: Various change of neurotransmitters happen due to giving of ECT , one of the main change is the level of serotonin, dopamine and nor adrenaline. But in recent advances in functional imaging one of the most researched and evidence base if for the recent advances in neurobiology of electro convulsive therapy that too in the change of BDNF in the brain that is said to be responsibe for reduction of suicidal ideas in depressed patients. Ref.Kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 1066