This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Which of the following antiglaucoma medication is UNSAFE in infants ? 
Select and explain. 
A. Timolol, B. Brimonidine, C. Latanoprost, D. Dorzolamide
B: Brimonidine
Answer: B: Brimonidine 
Explanation: Apraclonidine and brimonidine can cross blood brain barrier and may result in CNS depression and apnea in neonates. ‘These are threfore contra-indicated in children less than 2 years.