This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Which is the best marker of SLE ? 
Select and explain. 
A. Anti Sm antibodies, B. Anti dsDNA antibodies, C. Anti histone antibodies, D. Anti Ro Antibodies
B: Anti dsDNA antibodies
Answer: B: Anti dsDNA antibodies 
Explanation: Ans. is 'b' i.e., Anti dsDNA antibodies Antibodies to double - stranded DNA and the Smith (Sm) antigen are viually diagnostic of SLE".