This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Oesophagus, Subject name: Surgery
Endoscopic treatment of leiomyoma of esophagus is contraindicated due to: 
Select and explain. 
A. Infection, B. Chances of dissemination, C. Perforation, D. Perforation and dissemination
C: Perforation
Answer: C: Perforation 
Explanation: Ans. (c) PerforationRef: Shackelford 7th Edition, Pages 518-520* Leiomyoma endoscopic biopsy or surgery is not advised due to risk of perforation