This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Anatomy
In langerhans cell hystiocytosis,the characteristic abnormality seen on microscopy is: 
Select and explain. 
A. Birbecks granules, B. Foamy macrophages, C. Giant cells, D. Plasma cells
A: Birbecks granules
Answer: A: Birbecks granules 
Explanation: Langerhans cell histiocytosis is characterised by the presence of Birbeck granules in the cytoplasm.(ref Robbins 9th/622)