This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti-Neoplastic Agents, Subject name: Pharmacology
Most cardiotoxic anticancer drug - 
Select and explain. 
A. Anthracycline, B. Alkylating agent, C. Platinum compound, D. Bisphosphonates
A: Anthracycline
Answer: A: Anthracycline 
Explanation: Ans. is 'a' i.e., Anthracycline o The major toxicity of anthracyclines is potentially irreversible cumulative dose related toxicityo They may causes arrhythmias and cardiomyopathy. Because of their carditoxicity these drugs should be avoided in the patient mentioned in the question.