This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetic and genetic disorders, Subject name: Pediatrics
Single gene defect causing multiple unrelated problems 
Select and explain. 
A. Pleiotropism, B. Pseudodominance, C. Penetrance, D. Anticiaption
A: Pleiotropism
Answer: A: Pleiotropism 
Explanation: Pleiotropism : A gene that has multiple phenotypic effects It is a special interest because it helps in understanding the relationships between different organisms of the same individuals Examples: I. Drosophila bar eyed individuals may be significantly altered by the wing nature II. Seed coat colour gene of sweet pea controls flower colour and also red spot in leaf axils II. Sickle cell anemia in human . Reference: GHAI Essential pediatrics, 8th edition