This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Medicine
Laboratory evaluation for the differential diagnosis of chronic myeloproliferative disorders includes at thefollowingexcept. 
Select and explain. 
A. Chromosomal evaluation, B. Bone marrow aspiration, C. Flow-cytometric analysis, D. Determination of red blood cell mass
C: Flow-cytometric analysis
Answer: C: Flow-cytometric analysis 
Explanation: <p>In chronic myeloproliferative disorder, chromosomal evaluation is needed to identify Philadelphia chromosome(CML) & trisomy 20(polycythemia vera). Bone marrow examination reveals hypercellularity with myeloid predominance in CML & erythroid hyperplasia in PV & hyperdiploid megakaryocytes in essential thrombocytopenia. Red cell mass will be increased in PV.</p><p>Reference :Harsh mohan textbook of pathology sixth edition pg no 358.</p>