This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
Basement membrane degeneration is mediated by: 
Select and explain. 
A. Metalloproteinases, B. Oxidases, C. Elastases, D. Hydroxylases
A: Metalloproteinases
Answer: A: Metalloproteinases 
Explanation: A i.e. MetalloproteinasesZinc dependent matrix metalloproteinases (MMP) degrade collagen and other extracellular matrix proteins (including that of basement membrane)Q.