This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetics And Genetic Disorders, Subject name: Pediatrics
Which of the following condition is associated with cholestasis and butterfly shaped vertebra? 
Select and explain. 
A. Williams syndrome, B. Alagille syndrome, C. Holt Oram syndrome, D. Turner syndrome
B: Alagille syndrome
Answer: B: Alagille syndrome 
Explanation: Ans. B. Alagille syndromeCholestasis with butterfly shaped vertebra is associated with the Alagille syndrome; cause is mutation in the jagged 1 gene. It has an autosomal dominant inheritance.