This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Drugs, Subject name: Medicine
Which one of the following medications is most likely to be responsible for this appearance? 
Select and explain. 
A. Clarithromycin, B. Dexamethasone, C. Doxorubicin, D. Efavirenz
C: Doxorubicin
Answer: C: Doxorubicin 
Explanation: Answer C. DoxorubicinSeveral chemotherapeutic drugs (including doxorubin and cyclophosphamide) cause dyspigmentation. Other groups of drugs that cause this problem include antimalarials, amiodarone, heavy metals (but not iron), tetracyclines, and antipsychotics.