This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.N.S, Subject name: Medicine
A 4 month pregnant lady on treatment with valproate regularly asked for your advice regarding taking the drug during pregnancy. What is the best course of action 
Select and explain. 
A. Immediately tape off valproate and sta lamotrigine, B. Change to carbamazepine, C. Continue valproate and monitor blood levels, D. Slowly tape dose of valproate
B: Change to carbamazepine
Answer: B: Change to carbamazepine 
Explanation: K.D Tripathy essentials of medical pharmacology 7th edition . *Valproate used during pregnancy produced spina bifida and other neural tube defects in off spring:should be avoided *Incidence of minor foetal malformation repoed with carbamazepine *