This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: A.N.S., Subject name: Pharmacology
Drug causing ocular hypotension with apnea in an infant is: 
Select and explain. 
A. Latanoprost, B. Brimonidine, C. Timolol, D. Acetazolamide
B: Brimonidine
Answer: B: Brimonidine 
Explanation: Ans. (B) Brimonidine(Ref: Goodman and Caiman 13th/e p1259)Brimonidine causes CNS depression in newborn babies and can result in apnea, so it is contraindicated in such patients.Ocular adverse effects of anti-glaucoma drugsDrugAdverse EffectMiotics (Pilocarpine)CataractStenosis of nasolacrimal systemPGF2 analogs (Latanoprost)Heterochromia iridisGrowth of eyelashesCystoid Macular EdemaApraclonidineLid retractionBrimonidineCNS depression and apnea in newbornAdrenalineConjunctival pigmentation