This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
Recommended vaccines for rabies ? 
Select and explain. 
A. Semple, B. Duck embryo vaccine, C. Suckling mouse brain vaccine, D. HDCV
D: HDCV
Answer: D: HDCV 
Explanation: Ans. is 'd' i.e., HDCV . A Cell culture vaccines ( HDCV, chick embryo fibroblast, vero continous cell line) are most potent safer with fewer side effects and require fewer injections than the others. . Because of their potency and low cost, second generation tissue culture vaccines ( chick embryo fibryoblast, vero continous cell line) are preferred. . So, the recommended vaccines for rabies are second generation tissue vaccines? *) Chick embryo fibroblast ii) Vero continous cell line . As these vaccines are not given in option, preferred alternative is human diploid cell vaccine (HDCV).