This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hematology, Subject name: Pediatrics
All of the following are true of ss thalassemia major, except 
Select and explain. 
A. Splenomegaly, B. Target cells on peripheral smear, C. Microcytic hypochromic anemia, D. Increased osmotic fragility
D: Increased osmotic fragility
Answer: D: Increased osmotic fragility 
Explanation: In thalassemia major there will be marked splenomegaly,hypochromic microcytic anemia and target cells in peripheral smear. osmotic fragility decreases. Reference: GHAI Essential pediatrics, 8th edition