This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Skin
The pathognomonic sign of neurofibromatosis is 
Select and explain. 
A. Cafe-au-lait macules, B. Axillary frekling, C. Shagreen patch, D. None of the above
B: Axillary frekling
Answer: B: Axillary frekling 
Explanation: B i.e. Axillary freckling Neurofibromatosis is autosomal dominantQ disorder. Axillary freckling (crowe sign) is a pathognomic sign of von- Reckling hausen's type 1 neurofibromatosisQ. Cafe - au - lait macules alone are not absolutely diagnostic of NF1, regardless of their size and number.