This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Other topics and Adverse effects, Subject name: Anatomy
Which of the following statements about amoebicide is least accurate 
Select and explain. 
A. Diloxanide furoate it is a luminal amoebicide, B. Emetine is contraindicated in pregnancy and in patients with Cardiac disease, C. Metronidazole has little activity in the gut lumen, D. Paromomcin is effective in extraintestinal amoebiasis
D: Paromomcin is effective in extraintestinal amoebiasis
Answer: D: Paromomcin is effective in extraintestinal amoebiasis 
Explanation: Ref-KDT 6/e p896,807 Paromomycin and diloxanide furoate are luminal ameobicamo