This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
In sickle cell anemia replacement is: 
Select and explain. 
A. Valbglu in b6, B. Glu by val in b6, C. Hist val b8, D. 6A
B: Glu by val in b6
Answer: B: Glu by val in b6 
Explanation: B i.e. Glu by val in b6