This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
Most common cause of seizure in newborn is ? 
Select and explain. 
A. Hypoxia induced ischemic encephalopathy, B. Hypocalcemia, C. Metabolic abnormality, D. Sepsis
A: Hypoxia induced ischemic encephalopathy
Answer: A: Hypoxia induced ischemic encephalopathy 
Explanation: Ans. is 'a' i.e., Hypoxia induced ischemic encephalopathy DIFFERENTIAL DIAGNOSIS OF NEONATAL SEIZURES o Hypoxic ischemic encephalopathy --> Most common cause (60%). o Intracranial hemorrhage o Infection o Hypoglycemia o Hypocalcemia, Hypomagnesemia o Hyponatremia o Disorder of amino and organic acid metabolism, hyperammonemia o Pyridoxine deficiency o Developmental defects o Drug withdrawl o No cause found o Benign familial neonatal seizures