This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anaesthesia, Subject name: Pharmacology
All are vasodilators except. 
Select and explain. 
A. Procaine, B. Lidocaine, C. Cocaine, D. Chlorprocaine
C: Cocaine
Answer: C: Cocaine 
Explanation: Ans. (C) Cocaine(Ref: Katzung 11th/e p448)All local anaesthetics cause vasodilation except cocaine. It blocks reuptake of nor-adrenaline and result in sympathetic overactivity. Therefore, cocaine can cause hypertension and cardiac arrhythmias.