This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Classification, Coho Study, Subject name: Social & Preventive Medicine
The natural history of disease is best established by: 
Select and explain. 
A. Randomized control trials, B. Clinical trials, C. Descriptive studies, D. Coho studies
D: Coho studies
Answer: D: Coho studies 
Explanation: The Natural history of disease is best established by coho studies. COHO STUDY: Forward looking study Prospective study Cause to effect study Risk factor to disease study Exposure to outcome study Follow-up study Incidence study