This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Drug and Alcohol-Related Conditions, Subject name: Psychiatry
Wernicke's encephalopathy is due to deficiency of - 
Select and explain. 
A. Folic acid, B. Thiamine, C. Ascorbic acid, D. Pyridoxine
B: Thiamine
Answer: B: Thiamine 
Explanation: Ans. is 'b' i.e., Thiamine Wernike's encephalopathyo This is caused by thiamine deficiency.o There are acute degenerative changes in thalamus, hypothalamus and mammillary bodies,o Signs are: confusion, ocular paresis and nystagmus, staggering gait and peripheral neuropathy.