This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
About AFP all are true except 
Select and explain. 
A. MSAFP detected 16-18 weeks of gestation, B. Decreased in down syndrome, C. MSAFP is unrelated to period of gestation, D. Diabetic patients have increased AFP level
D: Diabetic patients have increased AFP level
Answer: D: Diabetic patients have increased AFP level 
Explanation: AFP increased in

wrong gestational age
Rh isoimmunisation
open neural tube defects
multiple pregnancy
IUFD
Anterior abdominal wall defects
renal anomalies