This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunology, Subject name: Microbiology
A child upon ingestion of shellfish , developed tingling sensation in the mouth, swelling of the face, lips and tongue and also complained of abdominal pain and dizziness. This is an example of _ 
Select and explain. 
A. IgG mediated reaction, B. IgA mediated reaction, C. T cell mediated cytotoxicity, D. IgE mediated reaction
D: IgE mediated reaction
Answer: D: IgE mediated reaction 
Explanation: This is an example of an IgE mediated type of hypersensitivity reaction. The primary mediators are histamine and serotonin. The secondary mediators are prostaglandins and leukotrienes. The clinical manifestations may be local or systemic and range from mild rhinitis to fatal anaphylaxis. Reference: Ananthanarayan and Paniker&;s Textbook of Microbiology Tenth edition