This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Sexually Transmitted Infections, Subject name: Dental
The most frequent cause of recurrent genital ulceration in a sexually active male is: 
Select and explain. 
A. Herpes genitalis, B. Aphthous ulcer, C. Syphilis, D. Chancroid
A: Herpes genitalis
Answer: A: Herpes genitalis 
Explanation: Sexually transmitted herpes simplex virus type II(HSV) infections cause most genital ulcer disease. Disease % Herpes 62 % Chanchroid 12 to 20 % Syphilis 13 % LGV and Granuloma Inguinale 5% Herpes ulcers are painful, vesicular, multiple and are associated with firm tender lymphadenopathy.