This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Medicine
Diagnostic criteria of Hodgkin&;s disease are A/E - 
Select and explain. 
A. RS cells, B. Atypical cells in background, C. Sclerosing pattern, D. CD 30 present
B: Atypical cells in background
Answer: B: Atypical cells in background 
Explanation: <p>RS cells are invariably accompanied by a variable number of atypical Hodgkin cells which are believed to be precursor RS cells but are not considered diagnostic of HD.</p><p>Reference :Harsh mohan textbook of pathology sixth edition pg no 370.</p>