This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
Mutations in connexin can cause: 
Select and explain. 
A. Charcot Marie Tooth disease, B. Huntington's chorea, C. Freidrich's ataxia, D. None of the above
A: Charcot Marie Tooth disease
Answer: A: Charcot Marie Tooth disease 
Explanation: At least 20 different genes code for connexins in humans, and mutations in these genes can lead to diseases that are highly selective in terms of the tissues involved and the type of communication between cells produced. For instance, X-linked Charcot-Marie-Tooth disease is a peripheral neuropathy associated with mutation of one paicular connexin gene. Ref: Ganong's Review of Medical Physiology 23rd edition, Chapter 2.