This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Which one of the following is least likely to occur in late extra articular sero-positive rheumatoid arthritis - 
Select and explain. 
A. Neutropenia, B. Dry eye, C. Leg ulcers, D. Hepatitis
D: Hepatitis
Answer: D: Hepatitis 
Explanation: None