This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Which of the following is the most frequent presentation of osteoporosis? 
Select and explain. 
A. Weight loss, B. Bowing of legs, C. Veebral compression fracture, D. Low serum calcium level
C: Veebral compression fracture
Answer: C: Veebral compression fracture 
Explanation: Compression fracture or collapse of veebrae resulting in back ache is the usual symptom of osteoporosis. Osteoporosis is a skeletal disorder characterized by a loss of bone osteoid that reduces bone integrity resulting in increased risk of fractures. It is associated with normal serum calcium, phosphate and parathyroid hormone level. Reference: Current Medical Diagnosis and Treatment 2013, chapter 26.