This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anticoagulants and Coagulants, Subject name: Pharmacology
Phytonadione is used in treatment of which toxicity- 
Select and explain. 
A. Heparin, B. Oral anticoagulant, C. Digoxin, D. Streptokinase
B: Oral anticoagulant
Answer: B: Oral anticoagulant 
Explanation: Ans. is 'b' i.e., Oral anticoagulant Vit K1 (Phytonadione) is the preparation of choice for overdose of oral anticoagulants (Dicumarol).Remembero Specific antidote for oral anticoagulants - Vit K1o Specific antidote for heparin - Protamineo Specific antidote for fibrinolytics (e.g. streptokinase) - antifibrinolytics (epsilone amino-caproic acid, Tranaexaemic acid, Aprotinin).