This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Autonomic nervous system, Subject name: Pharmacology
Which of the following is a relatively cerebroselective anticholinesterase found to afford symptomatic improvement in Alzheimer&;s disease 
Select and explain. 
A. Donepezil, B. Pyridostigmine, C. Pyritinol, D. Gemfibrozil
A: Donepezil
Answer: A: Donepezil 
Explanation: Rivastigmine:- This lipophilic relatively cere-broselective ChE inhibitor has been introduced for Alzheimer's disease (AD). Donepezil:- Another centrally acting anti-AChE that has produced cognitive and behavioral improvement in AD. It is long-acting and suitable for once daily administration. Galantamine:- This natural alkaloid inhibitor of cerebral AChE has in addition weak agonistic action on nicotinic receptors. It is being used to afford symptomatic relief in AD. Ref:- kd tripathi; pg num:-108