This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Ophthalmology
Posterior lenticonus is seen in ? 
Select and explain. 
A. Alpo's syndrome, B. Lowe's syndrome, C. Marfan syndrome, D. Homocystinuria
B: Lowe's syndrome
Answer: B: Lowe's syndrome 
Explanation: Ans. is 'b' i.e., Lowe's syndrome Lenticonus refers to cone-shaped elevation of the anterior pole (anterior lenticonus) or posterior pole (posterior lenticonus) of the lens. Anterior lenticonus is seen in Alpo's syndrome. Posterior lenticonus is seen in Lowe's syndrome. On distant direct ophthalmoscopy, lenticonus present as an oil globule lying in the center of red reflex. Slit-lamp examination confirms the diagnosis.