This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunology, Subject name: Microbiology
Antibody diversity is due to - 
Select and explain. 
A. Gene rearrangement, B. Gene translocation, C. Antigenic variation, D. CD40 molecules
A: Gene rearrangement
Answer: A: Gene rearrangement 
Explanation: The large and diverse population of antibody paratope is generated by random recombination events of a set of gene segments that encode different antigen-binding sites (or paratopes), followed by random mutations in this area of the antibody gene, which create fuher diversity Ref: Ananthanarayan & Parker's textbook of microbiology 9th edition pg: 94-97