This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
High first pass metabolism is seen in: 
Select and explain. 
A. Lignocaine, B. Propranolol, C. Salbutamol, D. All of these
D: All of these
Answer: D: All of these 
Explanation: - Among given options Lignocaine, Propranolol and Salbutamol has high first pass metabolism.