This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
The complete genome sequence of M. tuberculosis comprises of which of the following? 
Select and explain. 
A. 4100 genes, B. 3100 genes, C. 2100 genes, D. 1100 genes
A: 4100 genes
Answer: A: 4100 genes 
Explanation: The complete genome sequence of M. tuberculosis comprises 4043 genes encoding 3993 proteins and 50 genes encoding RNAs and its high guanine-plus-cytosine content (65.6%) is indicative of an aerobic lifestyle. Reference : Harrisons Principles of Internal Medicine, 18th Edition, Page 1340