This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Conventional cytogenetics are difficult in solid tumors ,especially in case of Ca Cx due to: 
Select and explain. 
A. High mitotic rate, B. Bacterial contamination of the specimen, C. Good metaphase activity, D. Inadequate biopsy specimen
D: Inadequate biopsy specimen
Answer: D: Inadequate biopsy specimen 
Explanation: . Inadequate biopsy specimen