This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Autacoids, Subject name: Pharmacology
Wof is long acting NSAID 
Select and explain. 
A. Aspirin, B. Ibuprofen, C. Diclofenac, D. Piroxicam
D: Piroxicam
Answer: D: Piroxicam 
Explanation: ENOLIC ACID DERIVATIVES (Oxicams) Piroxicam:- It is a long-acting potent NSAID with anti-inflammatory potency similar to indomethacin and good analgesic-antipyretic action. It is a nonselective, reversible inhibitor of COX; lowers PG concentration in synol fluid and inhibits platelet aggregation--prolonging bleeding time. In addition, it decreases the production of IgM rheumatoid factor and leucocyte chemotaxis. Pharmacokinetics:- It is rapidly and completely absorbed: 99% plasma protein bound; largely metabolized in liver by hydroxylation and glucuronide conjugation; excreted in urine and bile; enterohepatic cycling occurs. Plasma t 1/2 is long nearly 2 days. (Due to enterohepatic circulation). Ref:- kd tripathi;pg num:-201