This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Which of the following is not seen in sickle cell disease 
Select and explain. 
A. Gamma Gandy bodies, B. Moderate to massive spleenomegaly, C. Fish mouth vertebra, D. Decreased ESR
B: Moderate to massive spleenomegaly
Answer: B: Moderate to massive spleenomegaly 
Explanation: Autosplenectomy occurs in sickle cell disease, not spleenomegaly.