This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Gynaecology & Obstetrics
Beneficial effects of hormone replacement therapy in early menopause 
Select and explain. 
A. Increased Nitric oxide, B. Increased Endothelin, C. Decreased COX-2, D. Increased TNF-α
A: Increased Nitric oxide
Answer: A: Increased Nitric oxide 
Explanation: None