This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Oncology, Subject name: Medicine
A 64-year-old man is receiving chemotherapy for squamous cell cancer of the lung. He has now developed erythema, induration, thickening, and eventual peeling of the skin on the fingers, palms, and soles of his feet.For the above patient with an adverse reaction, select the most likely chemotherapeutic agent. 
Select and explain. 
A. methotrexate, B. cytarabine, C. 5-fluorouracil (5-FU), D. bleomycin
D: bleomycin
Answer: D: bleomycin 
Explanation: Although lung injury is the most serious complication of bleomycin, this unusual skin reaction is more frequent, occurring in almost 50% of patients.