This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
True about mycetoma - 
Select and explain. 
A. Commonly occurs in hands, B. Commonly erodes bone, C. Drains through lymphatics, D. Antibiotics has no role
B: Commonly erodes bone
Answer: B: Commonly erodes bone 
Explanation: Mycetoma 

Commonly occurs in the foot.
The infection runs as a relentless course over many years, with the destruction of contiguous bone and fascia.
Spread to distant sites does not take place (does not drain through lymphatics).


Actinomycetoma may respond to prolonged combination chemotherapy eg. streptomycin and dapsone.

Treatment 
Actinomycetoma

May respond to prolonged combination chemotherapy - Streptomycin and dapsone or streptomycin and cotrimoxazole.

Eumycetoma

Rarely respond to chemotherapy.
Some cases caused by madurella mycetomatis may respond to ketoconazole or itraconazole.