This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Intake of high protein diet causes? 
Select and explain. 
A. Increased gluconeogenesis, B. Increased beta oxidation, C. Decreased glycogenolysis, D. Metabolic alkalosis
A: Increased gluconeogenesis
Answer: A: Increased gluconeogenesis 
Explanation: Ans. is 'a' i.e., Increased gluconeogenesis High protein diet is generally recommended for weight loss.High protein diet is found to increase the rate of gluconeogenesis. Glucogenic aminoacids in circulation is found to stimulate glucagon release.Glucagon stimulates Phosphoenol pyruvate carboxykinase and glucose 6 phosphatase. This way blood glucose is increased and this high blood glucose also has a satiation effect.High protein diet also stimulates glycogenolysis because of its effect on glucagon release.