This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
X - linked inheritance of alport's syndrome is due to mutation of _________ 
Select and explain. 
A. COL4A5 gene, B. COL4B6 gene, C. COL3A5 gene, D. COL4A3 gene
A: COL4A5 gene
Answer: A: COL4A5 gene 
Explanation: Mutation of COL4A5 gene ⇒ X - linked inheritence
Mutation of COL4A3 ,COL4A4 gene ⇒ Autosomal inheritence