This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Neoplastic Disorders, Subject name: Surgery
Treatment of choice for squamous cell carcinoma of anus is? 
Select and explain. 
A. Chemotherapy, B. Chemoradiation, C. Sphincter sparing surgery, D. Monoclonal antibodies
B: Chemoradiation
Answer: B: Chemoradiation 
Explanation: ANSWER: (B) ChemoradiationREF: Schwatrtz 8th ed p-1096Squamous cell carcinoma of the anal margin (distal to dentate line): treated with wide local excisionSquamous cell carcinoma of the anal canal (proximal to dentate line): chemotherapy followed by radiation (chemoradiation), abdomino perineal resection is done for residual cases.Drugs used: 5-FU, mitomycin, bleomycin, cisplatin, doxorubicinMost common anal canal cancer: squamous cell carcinoma