This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Lens, Subject name: Ophthalmology
Antimicrobial resistance in frequent lens user is due to - 
Select and explain. 
A. Biofilm formation, B. Improper handling, C. Unhygienic use of lens, D. Low potency of antibiotics
A: Biofilm formation
Answer: A: Biofilm formation 
Explanation: Ans. is 'a' i.e., Biofilm formation o The contaminated contact lens provides Psuedomonas aeruginosa an ideal site for attachment and biofilm productiono Continuous contact of the eye to the biofilm- infested lens can lead to serious ocular diseases, such as keratitis (corneal ulcers).o The biofilm also prevent effective penetration of the antibiotics, which increase the chances of antibiotic resistance.