This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology and breast, Subject name: Surgery
Treatment of Zollinger- Ellison syndrome include all except 
Select and explain. 
A. Proton pump inhibitors, B. Octreotide, C. Streptozotocin, D. Diazoxide
D: Diazoxide
Answer: D: Diazoxide 
Explanation: In most patients with ZES, gastric hypersecretion can be treated effectively with proton pump inhibitors.Octreotide can also help to control acid hypersecretion.Systemic chemotherapy is utilised in patients with diffuse metastatic gastrinomas. Streptozotocin in combination with 5-fluorouracil or doxorubicin is the first-line treatment.Ref: Bailey and Love 27e pg: 851