This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Lipids, Subject name: Biochemistry
Which of the following enzyme is absent in Wolman's disease? 
Select and explain. 
A. Cholestrol ester hydrolase, B. Acid hydrolase, C. Acyl-CoA carnitine, D. Acid lipase
D: Acid lipase
Answer: D: Acid lipase 
Explanation: Ans. D. Acid lipase (Ref. H-17th/ pg. 2454; Table 355-1)WOLMAN'S DISEASE# It is a lysosomal storage disorder, that occurs due to acid lipase deficiency.# Features: increased LDL levels, hypercholesterolemia, atherosclerosis, adrenal calcification and death in infancy itself.Disorders of Neutral LipidsDisorderEnzyme Deficiency (Specific Therapy)Stored MaterialClinical Types (Onset)Inheri-tanceNeuro- logic featuresLiver Spleen Enlarge- mentSkeletal DysplasiaEyeHemato logicUnique featuresWolman diseaseAcid lysoso- mal Lipase (BMT)Choles- terol esters, triglyce ridesInfantileARMild mental retarda- tion+++NoneNoneNoneAdrenal calcifi- cationCholes- teryl ester storage diseaseAcid lysoso- mal lipaseCholes- teryl estersChild- hoodARNoneHepato- megalyNoneNoneNoneCirrhosisFarber diseaseAcid cerami daseCeramideInfantile JuvenileAROccasio- nal men- tal retar- dation+-NoneMacular degene- rationNoneArthropa thy, subcu- taneous nodulePompe disease (135)Acid -gluco sidase (ET)Glyco- genInfantile late onsetARNeuro- muscu- lar+-NoneNoneNoneMyocar- diopathy