This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Reproductive physiology and hormones in females, Subject name: Gynaecology & Obstetrics
End product of prgesterone metabolism found in urine : 
Select and explain. 
A. Pregnenolone, B. 17-OH Pregnenolone, C. Pregnanediol, D. Pregnanetriol
C: Pregnanediol
Answer: C: Pregnanediol 
Explanation: Fate of progesterone : Within a few minutes after secretion almost all the progesterone is degraded to other steroids that have no progesteronic effect The major end product of progesterone degradation is pregnanediol. Approximately 10% is excreted in urine in this form. Ref: TEXTBOOK OF MEDICAL PHYSIOLOGY,GUYTON,Pg no:905,12th edition