This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Diagnosis in obstetrics, Subject name: Gynaecology & Obstetrics
Regarding alpha fetoprotein true statement is: 
Select and explain. 
A. Major source in fetal life is yolk sac, B. Commonly increased in wilm's tumour, C. Maximum level at 20th week, D. Half-life 5-7 days
A: Major source in fetal life is yolk sac
Answer: A: Major source in fetal life is yolk sac 
Explanation: AFP Produced by yolk sac and fetal liver Highest level of AFP in feta lserum and amniotic fluid isreached around 13 weeks and thereafter it decreases. Maternal serum level reaches peak around 32 weeks and increased in hepatoma,NTD,Rh isoimmunisation,IUFD,Multiple pregnancy D.C.DUTTA'S TEXTBOOK OF OBSTETRICS,Pg no:106,7th edition