This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Radiotherapy, Subject name: Radiology
"Eye of the Tiger" appearance in MRI is seen in 
Select and explain. 
A. Wilsons disease, B. Neuronal accumulation of iron, C. Alzheimer's, D. Hallervorden-Spatz syndrome
D: Hallervorden-Spatz syndrome
Answer: D: Hallervorden-Spatz syndrome 
Explanation: (D) Hallervorden-Spatz syndrome # Eye of the Tiger Sign refers to abnormal low T2 signal (due to abnormal accumulation of iron) on MRI in the globus pallidus with a longitudinal stripe of high signal (due to gliosis & spongiosis) that can be seen in:> Hallervorden-Spatz syndrome: Classical but not 100% pathognomonic. Progressive supranuclear palsy Early-onset levodopa-responsive parkinsonism Corticobasal ganglionic degeneration