This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Physiology
The oxygen dissociation curve of myoglobin & hemoglobin is different due to 
Select and explain. 
A. Hb can bind to 4 oxygen molecules, B. Cooperative binding in Hb, C. Myoglobin has little oxygen affinity, D. Hemoglobin follows a hyperbolic curve
B: Cooperative binding in Hb
Answer: B: Cooperative binding in Hb 
Explanation: The lack of cooperative binding is reflected in myoglobin dissociation curve.,a rectangular hyperbola is obtained. In the case of Hb, a sigmoid curve is obtained. A leftward shift in myoglobin O2 binding curve when compared to Hb demonstrates a higher affinity for O2 and thus promotes a orable transfer of O2 from Hb in the blood.Ref: Ganong&;s Review of medical physiology, 24th edition.Pg no. 643