This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of nucleic acids, Subject name: Biochemistry
Which of the following groups of protein assist in the folding of other proteins? 
Select and explain. 
A. Proteases, B. Proteosomes, C. Templates, D. Chaperones
D: Chaperones
Answer: D: Chaperones 
Explanation: Chaperones are present when the macromolecules perform their normal biological functions and have correctly completed the processes of folding and/or assembly.The chaperones are concerned primarily with protein folding.The first protein to be called a chaperone assists the assembly of nucleosomes from folded histones and DNA and such assembly chaperones, especially in the nucleus, are concerned with the assembly of folded subunits into oligomeric structures.