This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Pharmacology
Pegvaliase was approved by FDA in 2018 for 
Select and explain. 
A. Phenylketonuria, B. Pancreatic tumours, C. Crohn's disease, D. Glycogen storage disorders
A: Phenylketonuria
Answer: A: Phenylketonuria 
Explanation: Pegvaliase is a drug approved for the treatment of phenylketonuria. Chemically, it is a pegylated derivative of the enzyme phenylalanine ammonia-lyase that metabolizes phenylalanine to reduce its blood levels.