This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Goodpasture's syndrome is characterised by : 
Select and explain. 
A. Necrotising haemorrhagic interstitial pneumonitis, B. . Alveolitis, C. Patchy consolidation, D. Pulmonary oedema
A: Necrotising haemorrhagic interstitial pneumonitis
Answer: A: Necrotising haemorrhagic interstitial pneumonitis 
Explanation: Necrotising haemorrhagic interstitial pneumonitis Goodpasture's syndrome is an uncommon autoimmune disease. It shows presence of circulating autoantibiodies against non collagenous domain at a-3 chain of collagen IV. These antibodies initiate inflammatory distruction at basement membrane in glomeruli & lung alveoli, giving rise to RPGN & necrotising haemorrhagic interstitial pneumonitis.