This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
The development of resistance to conventional treatment has led WHO to recommend the use of combination therapies containing artemisinin derivative (artemisinin-based combination therapies also known as ACTs). All of the following combination therapies are recommended if such resistance is suspected, except : 
Select and explain. 
A. Artemether plus lumefantrine, B. Artesunate plus quinine, C. Artesunate plus pyrimethamine-sulfadoxine, D. Artesunate plus mefloquine
B: Artesunate plus quinine
Answer: B: Artesunate plus quinine 
Explanation: None