This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Magnetic Resonance Imaging, Subject name: Radiology
Hot Cross Bun Sign on MRI is seen in- 
Select and explain. 
A. Multisystem atrophy, B. Lewy body dementia, C. Progressive supranuclear palsy, D. Alzeihmer's disease
A: Multisystem atrophy
Answer: A: Multisystem atrophy 
Explanation: * HOT CROSS BUN SIGN - cross shaped hyperintensity in the center of pons * It is a classic feature of Multisystem atrophy type - C * Multisystem atrophy type - c has involvement of pontocerebellar pathway Figure: hot cross bun sign - MSA-C Figure showing Humming bird sign in Progressive supranuclear palsy. Figure showing Mickey-Mouse sign in Progressive supranuclear palsy.