This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti Histaminics, Subject name: Pharmacology
Which of the following drug is second generation antihistaminic: 
Select and explain. 
A. Promethazine, B. Loratadine, C. Diphenhydramine, D. Doxylamine
B: Loratadine
Answer: B: Loratadine 
Explanation: Ans. B. LoratadineSecond generation antihistaminic drug don't enter the CNS, no anticholinergic side-effects, drugs are cetirizine, levocetirizine, loratadine, ebastine, azelastine.