This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General anatomy, Subject name: Anatomy
Mitochondrial chromosomal abnormality leads to 
Select and explain. 
A. Leber's hereditary optic neuropathy, B. Angelman syndrome, C. Prader villi syndrome, D. Myotonic dystrophy
A: Leber's hereditary optic neuropathy
Answer: A: Leber's hereditary optic neuropathy 
Explanation: Ref Robbins 8/e p171;9/e p172 Example of mitochondrial inheritance is leber's hereditary optic neuropathy.leigh's disease ,MELAS - Mitochondrial encephalopathy Lactic acid Stroke like syndrome Neuropathy , ataxia, retinitis, Kearns Sayre syndromes, chronic progressive external opthalmoplegia,Pearson syndrome M