This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: NEET 2018, Subject name: Gynaecology & Obstetrics
Ideal time for doing quadruple test:- 
Select and explain. 
A. 8-12 weeks, B. 11-15 weeks, C. 15-18 weeks, D. 18-22 weeks
C: 15-18 weeks
Answer: C: 15-18 weeks 
Explanation: Triple test : screening test It's a screening test for down syndrome ( trisomy 21) Done between 16 and 18 weeks of gestation It involves estimation of three hormones : ( hCG|, AFP|, UE3| ) To the triple test, if the level of a fouh marker dimeric inhibin alpha are added, the test is called as QUAD test or Quadruple test ( inhibin A |) 1st trimester 2nd trimester Screening test Nuchal tranaslucency + - hCG + PAPP-A Quad test /tirple test Diagnostic test ( karyotyping ) Chronic villi sampling Amniocentesis