This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
Causative agent of sore throat is: September 2005 
Select and explain. 
A. Staphylococcus aureus, B. Streptococcus pyogenes, C. H. Influenzae, D. Corynebacterium diphtheriae
B: Streptococcus pyogenes
Answer: B: Streptococcus pyogenes 
Explanation: Ans. B: Streptococcus pyogenes The primary site of invasion of human body by streptococcus pyogenes is the throat. Primary bacterial pathogens that account for approximately 30% of cases of pharyngitis include Streptococcus pyogenes /Group A Beta Hemolytic Streptococci (common), group C streptococci (uncommon), group G streptococci (uncommon), Neisseria gonorrhoeae (uncommon), Corynebacterium diphtheriae (rare), and Corynebacterium hemolyticum (extremely rare). Viruses are isolated in approximately 40% of cases and include rhinovirus, adenovirus, parainfluenza virus, coxsackievirus, coronavirus, echovirus, herpes simplex virus, Epstein-Barr virus (mononucleosis), and cytomegalovirus. Other probable copathogens for pharyngitis in children include Staphylococcus aureus, Haemophilus influenzae, Branhamella catarrhalis, Bacteroides fragilis, Bacteroides oralis, Bacteroides melaninogenicus, Fusobacterium species, and Peptostreptococcus species.