This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Medicine
Which of the following most significantly increases the risk of Hepatocellular carcinoma ? 
Select and explain. 
A. HBV, B. CMV, C. EBV, D. HAV
A: HBV
Answer: A: HBV 
Explanation: Both case-control and coho studies have shown a strong association between chronic hepatitis B carrier rates and increased incidence of HCC.Ref: Harrison; 19th edition; Page no: 544