This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: SLE, Subject name: Medicine
HLA DRw 52 is associated with - 
Select and explain. 
A. SLE, B. Scleroderma, C. Sjogren, D. Behcet
C: Sjogren
Answer: C: Sjogren 
Explanation: Ans. is 'c' i.e., Sjogren syndrome o The frequency of HLA-DR52 in patients with primary Siogren syndrome is estimated to be 87%. but it is also significantly increased in secondary Sibgren syndrome that occurs with rheumatoid arthritis or systemic lupus erythematosus.o HLA B5/HLA B5I is related to Behcet disease.