This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti-Fungal Drugs, Subject name: Pharmacology
Mechanism of action of Triazoles:- 
Select and explain. 
A. Inhibits ergosterol biosynthesis, B. Inhibits tubulin, C. Inhibits glucan synthesis, D. Inhibits cell wall synthesis
A: Inhibits ergosterol biosynthesis
Answer: A: Inhibits ergosterol biosynthesis 
Explanation: The azoles act by inhibiting fungal cytochrome P450 enzyme 'lanosterol 14-demethylase' and thus impair ergosterol synthesis. These are presently the most extensively used antifungal drugs. Mechanism of action of other antifungal drugs: Polyene (Amphotericin B/Nystatin): Binds to ergosterol and creates pores. 5 Flucytosine : DNA polymerase inhibitor. Allylamine (Terbinafine, Butenafine, Naftifine): Inhibit enzyme squalene epoxidase. Griseofulvin : Act mitotic spindle Echinocandin (Caspofungin): Inhibit Beta 1-3