This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Other topics and Adverse effects, Subject name: Anatomy
Which of the following effects is unlikely to occur during treatment with imipramine? 
Select and explain. 
A. Elevation of seizure threshold, B. Mydriasis, C. Sedation, D. Urinary retention
A: Elevation of seizure threshold
Answer: A: Elevation of seizure threshold 
Explanation: (Ref: KDT 6/e p444) Imipramine is a tricyclic antidepressant. It inhibits the reuptake of serotonin and nor-adrenaline. In addition, it possesses anticholinergic and a-blocking propeies are: Increased risk of seizures due to lowering of Seizure threshold is an adverse effect of this drug.