This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Aplastic crisis in sickle cell anemia as compared to haemolytic crisis leads to 
Select and explain. 
A. Increased blood volume, B. Total leucocyte count decreased, C. Decrease in reticulocytes, D. Same findings
C: Decrease in reticulocytes
Answer: C: Decrease in reticulocytes 
Explanation: Aplastic crisis is an acute event caused by sudden decrease in red cell production. This is usually triggered by infection of erythroblasts by parvovirus B-19.
Hemolytic crisis is associated with hyperbilirubinemia and compensatory reticulocytosis.