This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Disorders of Pituitary Gland, Subject name: Pediatrics
Upper segment : lower segment ratio in Growth hormone deficiency: 
Select and explain. 
A. Increases, B. Decreases, C. Remains unchanged, D. Cannot comment
C: Remains unchanged
Answer: C: Remains unchanged 
Explanation: - Growth hormone deficiency is a cause of propoionate sho stature - so upper segment : lower segment ratio remains normal or unchanged. CLINICAL FEATURES OF GH DEFICIENCY: Delayed bone age, dentition, pubey, milestones Hypoglycemia Frontal bossing High pitched voice Sho stature DIAGNOSIS: 1. GH stimulation test : Done using insulin/ arginine/ clonidine/ glucagon Peak GH level <10 ng/ml - GH deficiency 2. Bone age < Chronological age Treatment:Recombinant GH injections subcutaneously