This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Renal carcinoma, Subject name: Pathology
From which of the following renal oncocytoma arises ? 
Select and explain. 
A. Loop of henle, B. Collecting duct, C. Proximal tubule, D. Bowman's capsule
B: Collecting duct
Answer: B: Collecting duct 
Explanation: RENAL ONCOCYTOMA: Benign epithelial neoplasm Arises from the intercalated cells of collecting ducts. Associated with genetic changes : loss of chromosomes 1 and Y Gross appearance- tumors are tan colored ,relatively homogeneous, and well encapsulated with central stellate scar Microscopically- characterized by a plethora of mitochondria which gives them tan color and granular eosinophilic cytoplasm.