This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetics, Subject name: Medicine
All of the following statement about H (hormone replacement therapy) are true except 
Select and explain. 
A. It increases the risk of coronary aery disease, B. It increases bone mineral density, C. It increases the risk of breast cancer, D. It increases the risk of endometrial cancer
D: It increases the risk of endometrial cancer
Answer: D: It increases the risk of endometrial cancer 
Explanation: There is evidence that the progestogen pa of combined H can counteract the cancer-causing effects of the oestrogen pa, when it comes to endometrial cancer. But it depends on the type of combined H used. But it's impoant to remember that combined H causes the greatest increase in risk for breast cancer Ref Robbins 9/e pg 154