This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
Multifactorial inheritance is seen in 
Select and explain. 
A. Neurofibroma, B. Haemophilia, C. Cardiac septal defects, D. Hypophosphatemic rickets
C: Cardiac septal defects
Answer: C: Cardiac septal defects 
Explanation: *The multifactorial disorders result from the combined actions of environmental influences and two or more mutant genes.*Some disorders of multifactorial inheritance are cleft lip/palate, congenital hea disease, coronary hea disease, hypeension, gout, diabetes, pyloric stenosis etc.*Note: Most of the congenital diseases are multifactorial. In our question "cardiac septal defect" is the only congenital disease.(Ref: Robbins 7/e p170)