This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
Calabar swelling is produced by? 
Select and explain. 
A. Onchocerca volvulus, B. Loa loa, C. Burgia malayi, D. Wuchereria bancrofti
B: Loa loa
Answer: B: Loa loa 
Explanation: Ans. is 'b' i.e., Loa - Loa Loiasis . Loiasis is caused by L. Loa (the African eye worm) . Habitat of adult worms is subcutaneous connective tissue of man; often in the sub-conjuctival tissue of the eye. . The worm passes its life cycle in two hosts : - Man - Chrysops (Mango or deer flies) . C/Fs --> Asymptomatic microfilaremia Calabar (fugitive) swelling - subcutaneous swelling Nephropathy Encephalopathy rare Cardiomyopathy Calabar swelling is due to hypersensitivity reaction to the adult worm.