This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
A patient, Hari has been diagnosed to have schizophrenia. Which of the following acts as a limiting factor in the use of clozapine as an antipsychotic drug in this patient ? 
Select and explain. 
A. Its potential to cause agranulocytosis, B. Its inability to benefit negative symptoms of schizophrenia, C. High incidence of extrapyramidal side effects, D. Production of hyperprolactinemia
A: Its potential to cause agranulocytosis
Answer: A: Its potential to cause agranulocytosis 
Explanation: None