This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Anaesthesia
Laundosine is a toxic metabolite of ? 
Select and explain. 
A. Atracurium, B. Pancuronium, C. Mivacurium, D. Vecuronium
A: Atracurium
Answer: A: Atracurium 
Explanation: Ans. is 'a' i.e., Atracurium Atracurium The unique feature of atracurium is inactivation in plasma by spontaneous nonenzymatic degradation (Hofmann elimination) in addition to that by alkaline ester hydrolysis. Consequently its duration of action is not altered in patients with hepatic / renal insufficiency or hypodynamic circulation -Preferred muscle relaxant for such patients as well as for neonates and the elderly. Atracurium is metabolised to laudanosine that is responsible for seizures. It can cause histamine release - Hypotension & bronchoconstriction