This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Psychiatry
Wernicke's encephalopathy can be prevented by : 
Select and explain. 
A. IV saline, B. Large amounts of glucose, C. Thiamine supplement, D. Imipramine
C: Thiamine supplement
Answer: C: Thiamine supplement 
Explanation: Prevention, as well as treatment of Wernicke's encephalopathy, is thiamine.
Wernicke's encephalopathy is due to deficiency of thiamine → Eary thiamine supplementation during treatment of malnutrition can prevent Wernicke's encephalopathy.
Wernicke's encephalopathy is treated by large doses of parenteral thiamine, which is believed to be effective in preventing the progression into Korsakoff's syndrome.