This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General anatomy, Subject name: Anatomy
Least common site for vegetation is 
Select and explain. 
A. Aerial stenosis, B. Mitral stenosis, C. Aerial septal defect, D. Mitral regurgitation
C: Aerial septal defect
Answer: C: Aerial septal defect 
Explanation: Ref Harrison 19 th ed pg 820 Infection most commonly involves hea valves but may also occur on the low-pressure side of a ventricular septal defect, on mural endocardium damaged by aberrant jets of blood or foreign bodies, or on intracardiac devices themselves. The analogous process involving aeriovenous shunts, aerio-aerial shunts (patent ductus aeriosus), or a coarctation of the aoa is called infective endaeritis.