This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Female Genital Tract, Subject name: Pathology
Marker for ovarian carcinoma in serum is - 
Select and explain. 
A. CA-125, B. Fibronectin, C. Acid Phosphatase, D. PSA
A: CA-125
Answer: A: CA-125 
Explanation: Ans. (a) CA-125(Ref: Robbins 9th/pg 1033; Am J Prev Med 13 (6): 444-6)*CA125- is a glycoprotein*Elevated levels in epithelial ovarian cancers*CA-125 is the most frequently used biomarker for ovarian cancer detectionElevated CA125- not a specific marker*In other cancers, including endometrial cancer, fallopian tube cancer, lung cancer, breast cancer and gastrointestinal cancer.*Benign conditions, such as endometriosis, PID, cirrhosis and diabetes mellitus