This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Carbohydrates, Subject name: Biochemistry
Which of the following statements regarding T.C. A cycle is true? 
Select and explain. 
A. It is an anaerobic process, B. It occurs in cytosol, C. It contains no intermediates for Gluconeogenesis, D. It is amphibolic in nature
D: It is amphibolic in nature
Answer: D: It is amphibolic in nature 
Explanation: Ans. D. It is amphibolic in natureTCA is catabolic as well as anabolic. Catabolic as it produces CO2 and H2 O and anabolic as it is indirectly linked to lipogenesis taking citric acid as the major intermediate.