This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Ejection click is heard in: 
Select and explain. 
A. Early systole, B. Late systole, C. Early diastole, D. Late diastole
A: Early systole
Answer: A: Early systole 
Explanation: The ejection sound is a sharp, high-pitched event occurring in early systole and closely following the first hea sound. Ejection sounds occur in the presence of semilunar valve stenosis and in conditions associated with dilation of the aoa or pulmonary aery. Ref: Harrison's principle of internal medicine 17th edition, chapter 220.