This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
What is true regarding Barret's esophagus: 
Select and explain. 
A. Seen in females, B. Premalignant, C. Responds to conservative management, D. Squamous metaplasia is seen
B: Premalignant
Answer: B: Premalignant 
Explanation: Answer is B (Premalignant condition) Barret's oesophagus is a premalignant condition with increased risk of adenocarcinoma. Barret's esophagus is more common in males More common in males (Males > Females)0 More common in White (Whites > Blacks)e More common with increasing ageU Barret's metaplasia once established does not respond to conservative management `Established Metaplasia does not regress with antisecretory treatment' - Harrison Although medical treatment does not regress the metaplastic changes, it is still advocated to prevent continued insult. Barret's esophagus is associated with columnar metaplasia and not squamous metaplasia.