This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of protein and amino acid, Subject name: Biochemistry
Hyperammonemia type I is due to deficiency of 
Select and explain. 
A. CPS-I, B. CPS-II, C. Arginase, D. Arginosuccinase
A: CPS-I
Answer: A: CPS-I 
Explanation: Deficiency of any of the urea cycle enzymes result in hyperammonemia. Carbamoyl phosphate synthetase1 deficiency or hyperammonemia type 1 is comparatively rare and is characterized by severe hyperammonemia.Ref: DM Vasudevan - Textbook of Biochemistry, 7th edition, page no: 205