This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cellular Pathology, Subject name: Pathology
Collagen affected in Osteogenesislmperfecta 
Select and explain. 
A. Type I, B. Type II, C. Type III, D. Type IV
A: Type I
Answer: A: Type I 
Explanation: Ans, is 'a' i.e., Type I o Osteogenesis imperfecta also known as brittle bone disease, or "Labstein syndrome" is a congenital bone disorder.o People with OI are bom with defective connective tissue, or without the ability to make it, usually because of a deficiency of Type-1 collagen.o This deficiency arises from an amino acid substitution of glycine to bulkier amino acids in the collagen triple helix structure.