This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Neoplastic cells in Franklin disease express 
Select and explain. 
A. CD5, B. CD10, C. CD55, D. CD79a
D: CD79a
Answer: D: CD79a 
Explanation: Answer- D. CD79aIn classic Franklin disease, neoplastic lymphocytes, plasmacytoid lymphocytes and plasma cells can be found in lymph nodes, Waldeyer ring, gastrointestinal tract and other extranodal sites, spleen, liver, bone marrow.Systemic symptoms- fever, weight loss, weakness, anorexia, recurrent bacterial infections.Neoplastic cells in Franklin disease, are believed to represent post germinal center B cells. The neoplastic cells contain gamma heavy chains in the cytoplasm ofcells (without light chains) and express CD 79a.Neoplastic lpnphocytes in this disorder express CD20, neoplastic plasma cells in this disorder express CD 138.