This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
A 24-year-old female presents with severe pain during menses (dysmenorrhea). To treat her symptoms, you advise her to take indomethacin in the hope that it will reduce her pain by interfering with the production of: 
Select and explain. 
A. Bradykinin, B. Histamine, C. Leukotrienes, D. Prostaglandin F2
D: Prostaglandin F2
Answer: D: Prostaglandin F2 
Explanation: Aspirin, indomethacin, and other nonsteroidal anti-inflammatory drugs (NSAIDs), in contrast, inhibit cyclooxygenase and therefore inhibit the synthesis of prostaglandins and thromboxane.