This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: parasitology, Subject name: Microbiology
Drug of choice to treat Toxoplasmosis in first-trimester of pregnancy is 
Select and explain. 
A. Spiramycin, B. Pyrimethamine-Sulphonamide, C. Atovaquone, D. Ivermectin
A: Spiramycin
Answer: A: Spiramycin 
Explanation: Compound Drug class Route Mechanism of action Clinical use Comment Spiramycin Macrolide Oral Blocks proteinsynthesis Toxoplasmosis Used to treat pregnantwomen Ref : Paniker's textbook of Medical Parasitology Pgno : 241,242