This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Apoptosis, Subject name: Pathology
Organelle which plays a pivotal role in apoptosis is: 
Select and explain. 
A. Cytoplasm, B. Golgi complex, C. Mitochondria, D. Nucleus
C: Mitochondria
Answer: C: Mitochondria 
Explanation: Programmed cell death is a central feature of normal tissue development and turnover and can be triggered by extrinsic signals (including cytotoxic T cells and inflammatory cytokines),or intrinsic pathways (including DNA damage and intracellular stress). Mitochondria play a central role in the intrinsic pathway of apoptosis.