This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Molecular studies on an abdominal lymph node containing lymphoma demonstrate t (2;8)(p12; q24) translocation. This is most compatible with which of the following diseases? 
Select and explain. 
A. Burkitt's lymphoma, B. Mantle cell lymphoma, C. Multiple myeloma, D. Small cell lymphoma
A: Burkitt's lymphoma
Answer: A: Burkitt's lymphoma 
Explanation: Burkitt's lymphoma is actually associated with three translocations. The common variant t(8; 14)(q24;q32), involving the oncogene myc on chromosome 8, and the heavy immunoglobulin chain on chromosome 14. The other two variants are: t(8;22)(q24;q11), involving myc and the lambda light chain immunoglobulin site, and t(2;8)(p12;q24), involving the kappa light chain and myc. Mantle cell lymphoma, multiple myeloma and small (not cleaved) cell lymphoma are associated with the t(11;14)(q13;q32) translocation involving bcl -1 and the heavy chain site.