This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hematology, Subject name: Pharmacology
If a fibrinolytic drug is used for the treatment of acute myocardial infarction, the adverse effect most likely to occur is: 
Select and explain. 
A. Acute renal failure, B. Development of antiplatelet antibodies, C. Encephalitis secondary to liver dysfunction, D. Hemorrhagic stroke
D: Hemorrhagic stroke
Answer: D: Hemorrhagic stroke 
Explanation: Bleeding is the most common adverse effect of anticoagulants, antiplatelets and fibrinolytic agents. Bleeding can manifest as hemorrhagic stroke in pts. on fibrinolytics therapy such as- Alteplase, Retaplase, Streptokinase. C/I of Fibrinolytics :- H/O Hemorrhagic Stroke H/O NON Hemorrhagic Stroke (within 1yr) Suspicion of aoic dissection Marked hypeension (SBP>180mm Hg and DBP>110mm Hg) Active internal bleed (Excluding menses)