This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
True statement about route of drug administration is: a) 80% bio-availability by I.V. injection  b) I.M. administration needs sterile technique. c) I.D. injection produces local tissue necrosis and irritation d) Inhalation produces delayed systemic bioavailability 
Select and explain. 
A. bc, B. ab, C. c, D. bd
A: bc
Answer: A: bc 
Explanation: 100% bioavailibility is seen in case of IV route.
Sterile technique is needed in case of I.V. and I.M. administration.
lrritation and local tissue necrosis is seen in case of injectable route like intramuscular or s.c. route.
In inhalational route, absorption of drugs takes place from vast surfaces of alveoli-so bioavailability is high and action is very rapid.