This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Which of the following is False regarding H.Pylori infection : 
Select and explain. 
A. With chronic infection urease breath test become negative, B. H.Pylori infection remain lifelong if untreated, C. Endoscopy is diagnostic, D. Toxigenic strains usually causes ulcer
A: With chronic infection urease breath test become negative
Answer: A: With chronic infection urease breath test become negative 
Explanation: Answer is A (With chronic infection urease breath test becomes negative) Urease breath test detects H. pylon infection by 'bacterial urease activity' and remains positive till the bacteria has not been eradicated with treatment. Thus urease breath test becomes negative only after eradication of organism following treatment and not with chronic Mfection. Despite a substantial humoral antibody response infection persists indefinitely (persists life long if untreated) Invasive diagnostic test are based on Endoscopic, endoscopy is a diagnostic application. H. pylori produces several virulence factors that have been implicated in the damage of mucosa.