This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Therapeutic use of acetylcholine is not possible because it is - 
Select and explain. 
A. Highly protein bound, B. Rapidly degraded, C. Repidly excreted, D. Orally ineffective
B: Rapidly degraded
Answer: B: Rapidly degraded 
Explanation: Ans. is 'b' i.e., Rapidly degraded o Acetylcholine is not used clinically because : I. It is metabolized very quickly by cholinesterase in plasma and is not effective even by i.v. route. 2. Action is nonselective