This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Which of the following is not a feature of chronic leukemia? 
Select and explain. 
A. Often diagnosed incidentally, B. Splenomegaly is common, C. Leucocytosis with circulating blasts and cytopenias are common, D. Lymphadenopathy is common
C: Leucocytosis with circulating blasts and cytopenias are common
Answer: C: Leucocytosis with circulating blasts and cytopenias are common 
Explanation: Presentation of leukaemia : Acute vs. Chronic Acute leukaemias Sho history of feeling unwell May present with neutropenic fever or bleeding Organ infiltration may occur: skin, gums, testes, meninges Peripheral blood usually shows leucocytosis with circulating blasts and cytopenias Chronic leukaemias Often diagnosed incidentally Usually long history of non-specific symptoms Splenomegaly is common Lymphadenopathy is common in chronic lymphocytic leukaemia Peripheral blood usually shows leucocytosis with circulating mature lymphocytes or myeloid cells; blasts are rare Ref: Leukaemia update. Pa 1: diagnosis and management ; BMJ 2013;346:f1660.