This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pharmacology
Bone resorption is enhanced by 
Select and explain. 
A. PGD2, B. PDF2, C. PGE2, D. PGI2
C: PGE2
Answer: C: PGE2 
Explanation: Bone resorption is increased by prostaglandin E2. Increased PGE2 stimulates binding of RANK ligand to RANK- stimulating osteoclast-causing resorption (REF.Essential of medical pharmacology K D TRIPATHI 6 Edition, Page No - 325)