This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Anatomy
The presence of the philadephia chromosome is associated with a worse prognosis in patients with which of the following diseases? 
Select and explain. 
A. Acute lymphoblastic leukemia, B. Acute myelogenous leukemia, C. Chronic lymphocytic leukemia, D. Chronic myelogenous leukemia
A: Acute lymphoblastic leukemia
Answer: A: Acute lymphoblastic leukemia 
Explanation: The presence of the philadelphia chromosome a translocation from the long arm of chromosome 22 to chromosome 9 (t,9,22) is associated with a more ourable prognosis in patients with chronic myelogenous leukemia but is associated with an unourable outcome in Acute lymphoblastic leukemia. (ref Robbins 8th/603)