This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
About scurvy true A/E – 
Select and explain. 
A. Subperiosteal haematoma with tenderness, B. Separation of epiphysis, C. ↑ S. alkaline phosphatase, D. Gingival bleeding
C: ↑ S. alkaline phosphatase
Answer: C: ↑ S. alkaline phosphatase 
Explanation: SCURVY

Scurvy is a disease resulting from deficiency of Vitamin 'C', which is required for collegen synthesis.

Function of Vit C and pathophvsiologv of scurvy
1. Collegeiz synthesis

Vitamin C is essential for the hydroxylation of lysine and proline in collegen formation.
Collegen is a component of intracellular matrix of capillaries, bone & teeth.