This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nutrition, Subject name: Medicine
Petechiae in scurvy is due to 
Select and explain. 
A. Platelet dysfunction, B. Thrombocytopenia, C. Clotting factor deficiency, D. Endothelial disintegration
D: Endothelial disintegration
Answer: D: Endothelial disintegration 
Explanation: Vitamin C deficiency causes defective formation of collagen with impaired healing of wounds, capillary haemorrhage and reduced platelet adhesiveness (normal platelets are rich in ascorbate) . Petechiae are formed due to minor bleeds from capillary vessels due to endothelial disintegration . Ref - Davidson 23e p716