This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Personality Disorders, Subject name: Psychiatry
All of the following is good prognostic factor for bipolar disorder EXCEPT: 
Select and explain. 
A. Acute onset, B. Early age of onset, C. Early responsive treatment, D. Associated depression
B: Early age of onset
Answer: B: Early age of onset 
Explanation: Ans. (b) Early age of onsetGood Prognostic FactorsPoor Prognostic Factors* Acute or abrupt onset* Typical clinical features* Severe depression* Well-adjusted premorbid personality* Good response to treatment* Co-morbid medical disorder, personality disorder or alcohol dependence* Double depression (acute depressive episode superimposed on chronic depression or dysthymia)* Catastrophic stress or chronic ongoing stress* Unfavourable early environment and early age of onset* Marked hypochondriacal features, or mood incongruent psychotic features* Poor drug compliance