This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: A.N.S., Subject name: Pharmacology
Cholinomimetics are useful in all of the following conditions except: 
Select and explain. 
A. Glaucoma, B. Myasthenia gravis, C. Post operative atony of bladder, D. Partial heart block
D: Partial heart block
Answer: D: Partial heart block 
Explanation: Ans. (D) Partial heart block(Ref: KDT 8th/e p119/122)Cholinergic drugs decrease the conduction from atrium to ventricle, thus should be avoided in partial heart blockCholinergic drugs like pilocarpine and physostigmine are used in angle closure glaucomaNeostigmine (acetylcholineesterase inhibitor, a cholinergic drug) is used for treatment of myasthenia gravisNeostigmine is also used for post operative paralytic ileus and post operative urinary retention.