This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Muscles are not involved in which glycogen storage disease: 
Select and explain. 
A. I, B. II, C. III, D. IV
A: I
Answer: A: I 
Explanation: A i.e. I Type I glycogen storage disease (Von Gierke's) is due to deficiency of Glucose -- 6- phosphataseQ.As this enzyme is absent in muscle, so muscles are not affected in Glycogen storage disease type I.Q. It affects liver,kidney and intestine.