This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Neoplastic disorders of WBCs, Subject name: Pediatrics
About Langerhans cell histiocytosis, true are all EXCEPT 
Select and explain. 
A. Peak incidence less than 3 years of age, B. Radiosensitive, C. Diffuse form is known as Letterer -siwe-disease, D. Gonadal involvement occurs
D: Gonadal involvement occurs
Answer: D: Gonadal involvement occurs 
Explanation: DISCUSSING THE OPTIONS ONE BY ONE: a. Peak incidence less than 3 years of age - True; More common and more severe in younger children b. Radiosensitive -True - as Bone lesions & Pituitary lesions causing DI, respond well to radiotherapy c. Diffuse form is known as Letterer-siwe disease -True d. Gonadal involvement occurs - False; Gonadal involvement is usually not seen in LCH. - Involvement of bones, scalp, pituitary, lungs, hematopoiesis is seen