This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
All of the following are pathological features associated with Crohn's disease except: March 2012 
Select and explain. 
A. Skip lesions, B. Non caseating granulomas, C. Cobblestone appearance, D. Toxic megacolon
D: Toxic megacolon
Answer: D: Toxic megacolon 
Explanation: Ans: D i.e. Toxic megacolonInflammatory bowel diseasePresence of multiple, separate, sharply delineated areas of disease, resulting in skip lesions, is characteristic of Crohn's disease and may help in differentiation from ulcerative colitisNon-caseating granuloma, a hallmark of Crohn disease, are found in approximately 35% of casesSparing of interspersed mucosa, a result of the patchy distribution of Crohn disease, results in coarsely textured, cobblestone appearance in which the diseased tissue is depressed below the level of mucosaIn Ulcerative colitis, inflammation and inflammatory mediators can damage the muscularis propria and disturb neuromuscular function leading to a colonic dilatation and toxic megacolon, which carries a significant risk of perforation