This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
High level of hCG is/are seen in all except : 
Select and explain. 
A. Down syndrome, B. Neural tube defect, C. Germ cell tumor, D. Gestational trophoblastic disease
B: Neural tube defect
Answer: B: Neural tube defect 
Explanation: Answer- B. Neural tube defect'High level of hCG auld be detected in- multiple pregnancy, hydatiform mole, choriocarcinoma, Down syndrome,Plasma lower levels are found in ectopic pregnancies & in spontaneous aboion.hCG is producedby the syncytiotrophoblast of the placenta.