This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous (Gynae), Subject name: Gynaecology & Obstetrics
Marker for menopause transition is: 
Select and explain. 
A. Menstrual irregularity, B. Hot flushes, C. | bone mass, D. Cessation of menstruation
A: Menstrual irregularity
Answer: A: Menstrual irregularity 
Explanation: Ans. is a, i.e. Menstrual irregularityRef: Williams gynae 3rd/ed, p472There is only one marker of menopausal transition, is menstrual irregularity. The cycles have long intervals (greater than 60 days).