This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
The degradation of P53 through Ubiquitous - dependent proteolysis by the binding of high-risk HPV protein is 
Select and explain. 
A. E6 and E7, B. E7, C. E6, D. E6, E7 and E8
C: E6
Answer: C: E6 
Explanation: None