This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Haematology, Subject name: Pathology
Pinch purpura are seen in - 
Select and explain. 
A. Secondary amyloidosis, B. Primary systemic amyloidosis, C. Pseudoxanthoma elasticum, D. Toxic shock syndrome
B: Primary systemic amyloidosis
Answer: B: Primary systemic amyloidosis 
Explanation: Answer is option 2, primary systemic amyloidosis. Systemic primary amyloidosis a. In primary systemic amyloidosis amyloid deposition occurs in the wall of the blood vessels, this leads to an increase in skin fragility. As a result, petechiae and purpura develop in clinically normal skin as well as in lesional skin following minor trauma. Therefore the skin lesions in case of primary systemic amyloidosis are called pinch purpura. These lesions are pink in colour and translucent. b. Common locations are c. Face (especially the periorbital and perioral region) Ref Robbins 9/e pg157