This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anatomy of skin, Subject name: Dental
Which Hormone is responsible for acne- 
Select and explain. 
A. Estrogen, B. Thyroid, C. Testosterone, D. Gonadotropins
C: Testosterone
Answer: C: Testosterone 
Explanation: The androgenic stimulus of the sebaceous glands plays an impoant role in etiopathogenesis of acne. Sebum production and excretion are regulated by androgenic hormones and mediators like EGF and IGF-1. androgens that are most impoant for sebum production: 5 alpha - dihydrotestosterone 5 alpha androsteine dihydroepiandrosterone testosterone Reference Harrison20th edition pg 1207