This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
Mouse is used for pathogenicity testing in ? 
Select and explain. 
A. M. Tuberculosis, B. C diptheriae, C. Bordetella peussis, D. Brucella
C: Bordetella peussis
Answer: C: Bordetella peussis 
Explanation: Ans. is 'c' i.e., Bordetella peussis Bordetella peussis is an obligate human parasite, but infection can be produced experimentally in several species of animals, the white mouse being most often employed. Intranasal inoculation produces a patchy interstitial pneumonia. Intraperitoneal inoculation of large doses is fatal due to toxemia. Intracerebral inoculation causes a fatal infection. Immunized mice are protected. This forms the basis for intracerebral mouse potency assay for peussis vaccines.