This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Unknown
Decreased glucose concentration in hepatic cells triggers all of the following except – 
Select and explain. 
A. Increased glucagon levels in blood, B. Activation of fructose-2,6-biphosphatase, C. Inhibition of phosphofructokinase-2, D. Increased fructose-2,6-biphosphate levels
D: Increased fructose-2,6-biphosphate levels
Answer: D: Increased fructose-2,6-biphosphate levels 
Explanation: Decreased glucose level leads to increased levels of glucagon .
Glucagon inhibits activity of PFK-2, and stimulates the activity of Fructose 2,6 biphosphatase .
Activation of fructose-2,6-biphosphatase leads to decreased level of fructose-2,6-biphosphate levels .
Ref: Harper’s illustrated Biochemistry 27th ed.