This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pharmacology
All the following increase insulin release except 
Select and explain. 
A. Rosiglitazone, B. Nateglinide, C. Glipizide, D. Exenatide
A: Rosiglitazone
Answer: A: Rosiglitazone 
Explanation: Glitazones -insulin sensitizers.they will not produce insulin from beta cells.a cells of pancreas There are insulin sensitizers and insulin secretogogues. insulin secretogogues increase the insulin secretion from the beta cells of pancreas.where as insulin sensitizres help in secsitizing the tissue to already present insulin. which include GLP 1 analogue,glinides,sulfonylureas. Ref: Katzung 12th ed.