This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: New born infants, Subject name: Pediatrics
Which of the following malformation in a newborn is specific for maternal insulin dependent diabates mellitus ? 
Select and explain. 
A. Transposition of great aeries, B. Caudal regression, C. Holoprosencephaly, D. Meningomyelocele
B: Caudal regression
Answer: B: Caudal regression 
Explanation: Caudal regression syndrome or sacral agenesis ( which is very rare ) is the congenital defect which is specific for maternal insulin dependent diabates mellitus. It is the abnormal fetal development of the lower spine--the caudal paition of the spine. Reference : page 243 Textbook of Obstetrics Sheila Balakrishnan 2nd edition