This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
The therapeutic efficacy of antihypertensive drugs is blunted by NSAIDs because they : 
Select and explain. 
A. Cause sodium excretion, B. Increase the clearance of antihypertensive drugs, C. Decrease the absorption of antihypertensive drugs, D. Decrease the synthesis of vascular prostacyclin
D: Decrease the synthesis of vascular prostacyclin
Answer: D: Decrease the synthesis of vascular prostacyclin 
Explanation: None