This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Vitamins and Minerals, Subject name: Biochemistry
Which of the following reaction is affected in patients of scurvy? 
Select and explain. 
A. Carboxylation, B. Acetylation, C. Hydroxylation, D. Transamination
C: Hydroxylation
Answer: C: Hydroxylation 
Explanation: Scurvy is due to deficiency of vitamin C. Vitamin C is required for lysyl and prolyl hydroxylases Vitamin C deficiency leads to defective post-translational modification of collagen - loss of tensile strength of blood vessels leading to:- - Bleeding gums -Ecchymoses - Easy bruisability -Poor wound healing (Features of scurvy).