This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Social & Preventive Medicine
According to RNTPC, case defination on sputum examination - 
Select and explain. 
A. 1 sample positive out of three samples, B. At least two samples positive out of two samples, C. Any of the two or both samples are positive out of two, D. 2 or 3 samples positive out of three
C: Any of the two or both samples are positive out of two
Answer: C: Any of the two or both samples are positive out of two 
Explanation: Ans. is 'c' i.e., Any of the two or both samples are positive out of two Two sputum smear samples are examined. If any of the two samples or both the samples are positive, the diagnosis of smear-positive TB is confirmed.