This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Chromosomal instability syndrome is 
Select and explain. 
A. Fanconi syndrome, B. Ataxia Telangectasia, C. Bloom syndrome, D. All of the above
D: All of the above
Answer: D: All of the above 
Explanation: Immunohistochemistry : Used in diagnosis of abnormal cells such as those found in tumors also used to understand the distribution and localization of biomarkers and differentially expressed protiens in different parts of a biological tissue.
Southern blotting : Used to detect DNA changes, e.g. whether genes have been deleted or rearranged. It is also used to detect RFLP. So it can detect gene expression.
Northern blotting : Used to detect RNA level. So used to analyze pattern and level of gene expression in different tissue.
Microarray : Can detect genomic changes as it measures many mRNA levels at once.