This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Infection, Subject name: Medicine
Malarial relapse is seen in - 
Select and explain. 
A. P. falciparum and P.vivax, B. P. falcipamm and P. malariae, C. P. ovale and P. malariae, D. ) P. vivax and P. ovale
C: P. ovale and P. malariae
Answer: C: P. ovale and P. malariae 
Explanation: Symptoms of relapse occur when reactivated hypnozoites are released into the systemic circulation. P. ovale malaria is not chloroquine resistant. Relapse due to P. ovale is relatively rare and may be prevented by administration of presumptive anti-relapse therapy like primaquine Ref Harrison20th edition pg 1312