This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of nucleic acids, Subject name: Biochemistry
Protein that initiates synthesis of RNA primers 
Select and explain. 
A. SSBs, B. DNA Ligase, C. DNA Primase, D. Topoisomerases
C: DNA Primase
Answer: C: DNA Primase 
Explanation: Classes of Proteins Involved in Replication Protein Function DNA polymerases Deoxynucleotide polymerization Helicases ATP -driven processive unwinding of DNA Topoisomerases Relieve torsional strain that results from helicase-induced unwinding DNA primase Initiates synthesis of RNA primers Single-strand binding proteins (SSBs) Prevent premature reannealing of dsDNA DNA ligase Seals the single strand nick between the nascent chain and Okazaki fragments on lagging strand Harper30e pg: 378