This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Psychiatry
Neurofibrillary tangles with senile plaques are seen in - 
Select and explain. 
A. Parkinson's disease, B. Alzheimer's disease, C. Schizophrenia, D. Tuberous sclerosis
B: Alzheimer's disease
Answer: B: Alzheimer's disease 
Explanation: Neurofibrillary tangles with senile plaque are characteristic of Alzheimer's disease. You should keep in mind that neurofibrillary tangles are not unique to Alzheimer's disease; they also occur in own syndrome, dementia pugilistica (punch drunk syndrome), Parkinson - dementia complex, hallervorden - Spatz disease, and Normally in old age. However, in these conditions, neurofibrillary tangles are without senile plaques.