This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Ovarian Tumors and Vulvar cancer, Subject name: Gynaecology & Obstetrics
The ovarian tumor which is most likely to be associated with virilization 
Select and explain. 
A. Granulosa tumor, B. Seoli-Leydig cell tumor, C. Immature teratoma, D. Gonadoblastoma
B: Seoli-Leydig cell tumor
Answer: B: Seoli-Leydig cell tumor 
Explanation: Seoli-Leydig cell tumor / Arrhenoblastomas Occur commonly in the third and fouh decades of life. Rare tumors They secrete androgens and cause defeminization followed by masculinization. Virilization: Permanent changes Hoarsness Breast atrophy Clitoromegaly Oligomenorrhea to amenorrhea Benign Rapid onst hirsutism Ovarian tumours which produce male sex hormones are called virilizing tumours.