This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
In acute inflammation, contraction of endothelial cells results in the following: 
Select and explain. 
A. Delayed transient increase in permeability, B. Early transient increase in permeability, C. Delayed permanent increase in permeability, D. Early permanent increase in permeability
B: Early transient increase in permeability
Answer: B: Early transient increase in permeability 
Explanation: Endothelial cell contraction leading to intercellular gaps in postcapillary venules is the most common cause of increased vascular permeability. Endothelial cell contraction occurs rapidly after binding of histamine, bradykinin, leukotrienes, and many other mediators to specific receptors, and is usually sho lived (15-30 min). Ref: Robbins Basic Pathology edited by Vinay Kumar, Abul K. Abbas, Jon C. Aster, 2012, Page 34.