This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of protein and amino acid, Subject name: Biochemistry
Maple syrup urine disease is due accumulation of 
Select and explain. 
A. Phenylalanine, B. Tyrosine, C. Branched chain amino acids, D. Tryptophan
C: Branched chain amino acids
Answer: C: Branched chain amino acids 
Explanation: Maple syrup urine disease is also called branched-chain ketonuria The basic defect is deficient decarboxylation of branched-chain ketoacids.Ref: DM Vasudevan - Textbook of Biochemistry, 7th edition, page no: 230