This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
In severe hypospadias the possibility of an intersex problem is settled by - 
Select and explain. 
A. Careful inspection of genitals, B. Biopsy for gonadal tissue, C. Karyotyping, D. Hormone assay
C: Karyotyping
Answer: C: Karyotyping 
Explanation: None