This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Which of the following viruses cause an acute febrile rash and produces disease in immunocompetent children but has been associated with transient aplastic crises in persons with sickle cell disease? 
Select and explain. 
A. Rubella, B. Varicella- zoster, C. Parvovirus, D. Rubella
C: Parvovirus
Answer: C: Parvovirus 
Explanation: Parvovirus B 19 is the causative agent of erythema infectiosum (fifth disease). It is associated with transient aplastic crisis in persons with hereditary hemolytic anemia. In adults, it is also associated with polyahralgia.