This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Howel-Jolly bodies may be seen after ? 
Select and explain. 
A. Hepatectomy, B. Splenectomy, C. Pancreatectomy, D. Cholecystectomy
B: Splenectomy
Answer: B: Splenectomy 
Explanation: Ans:B.) Splenectomy Howell-Jolly bodies They are histopathological findings of basophilic nuclear remnants (clusters of DNA) in circulating erythrocytes. Howell-Jolly bodies are seen with markedly decreased splenic function. Common causes include asplenia (post-splenectomy)or congenital absence of spleen. Other causes are radiation therapy involving the spleen, such as that used to treat Hodgkin lymphoma. Howell-Jolly bodies are also seen in: amyloidosis, severe hemolytic anemia, megaloblastic anemia, hereditary spherocytosis, heterotaxy with asplenia and myelodysplastic syndrome.