This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Skin
All of the following are true regarding albinism except: March 2009 
Select and explain. 
A. Autosomal recessive condition, B. Normal production of melanin, C. Tyrosinase positive are usually less severe, D. Prone to develop squamous cell carcinoma of skin
B: Normal production of melanin
Answer: B: Normal production of melanin 
Explanation: Ans. B: Normal production of melanin Oculocutaneous albinism is inherited as an autosomal recessive trait. Ocular albinism results from mutation in a gene on the X chromosome, which maps to band Xp22.3-22.2 and is inherited as an X-linked recessive trait. Two main variants: Tyrosinase positive are usually less severe whereas tyrosinase negative are more severe Molecular defect is absent/sparse production of melanin. Pateint presents with total absence of melanin in skin, hair and eyes. They are prone to develop squamous cell carcinoma of skin induced by ultraviolet rays, which develops on photo-exposed pas due to lack of protective melanin.