This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Nephritic Syndrome, Subject name: Pathology
Which of the following is the most common cause of nephrotic syndrome in adults? 
Select and explain. 
A. IgA nephropathy, B. Focal segmental glomerulosclerosis, C. Membranous nephropathy, D. Minimal change disease
B: Focal segmental glomerulosclerosis
Answer: B: Focal segmental glomerulosclerosis 
Explanation: Most common cause of nephrotic syndrome in adults is focal segmental glomerulosclerosis, followed by membranous nephropathy. Most common cause of nephrotic syndrome in children is minima change disease (MCD).