This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chemotherapy: General Principles, Subject name: Pharmacology
Figure shows the mechanism of action of which of the following drug? 
Select and explain. 
A. Nilotinib, B. Methotrexate, C. Pertuzumab, D. Cisplatin
A: Nilotinib
Answer: A: Nilotinib 
Explanation: Ans. (A) NilotinibTyrosine kinase activated by abl-bcr fusion result in CML. This enzyme can be inhibited byB:BosutinibI:ImatinibN:NilotinibD:DasatinibProteins:Ponatinib