This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pathology
First enzyme to be raised in MI is 
Select and explain. 
A. CPK-MB, B. LDH, C. Myoglobin, D. Troponin-I
C: Myoglobin
Answer: C: Myoglobin 
Explanation: The laboratory evaluation of MI is based on measuring blood levels of macromolecules that leak out of injured myocardial cells through damaged cell membranes these molecules include myoglobin, cardiac troponins T and I (TnT, TnI), creatine kinase (CK) (specifically the myocardial isoform, CK-MB), and lactate dehydrogenase. Troponins and CK-MB have high specificity and sensitivity for myocardial damage. (Robbins Basic pathology,9th edition.pg no.382)