This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Primary Immunodeficiency, Subject name: Pediatrics
In genetic deficiency of MPO, the increased susceptibility to infection is due to: 
Select and explain. 
A. Defective production of Prostaglandins, B. Defective rolling of' neutrophils, C. Inability to produce hydroxyl halide radicals, D. Inability to produce hydrogen peroxide
C: Inability to produce hydroxyl halide radicals
Answer: C: Inability to produce hydroxyl halide radicals 
Explanation: In MPO deficiency there is decreased microbial killing because of defective MPO--H2O2 system, so there is an inability to produce hydroxyl halide radicals.