This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hemolytic anemia, Subject name: Pediatrics
A child died soon after bih. On examination there was hepatosplenomegaly and edema all over body. Most probable diagnosis in: 
Select and explain. 
A. a-thalassemia, B. b-thalassemia, C. Hereditary spherocytosis, D. ABO incompatibility
A: a-thalassemia
Answer: A: a-thalassemia 
Explanation: - This case history suggests NON IMMUNE HYDROPS - seen in severe variety of alpha thalassemia (HbH or Hb Bas). - ABO incompatibility usually leads to mild hemolysis, which is not severe enough to lead to hydrops fetalis. - b-thalassemia - Doesn't present immediately after bih