This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anesthesia, Subject name: Pharmacology
True statement regarding Bupivacaine is: 
Select and explain. 
A. Used intravenously along with lignocaine, B. More cardiotoxic than lignocaine, C. Contraindicated in pregnancy, D. All of the above
B: More cardiotoxic than lignocaine
Answer: B: More cardiotoxic than lignocaine 
Explanation: Bupivacaine is more cardio toxic than Lignocaine as it more prone to prolong QTc interval and induce ventricular tachycardia or cardiac depression- should not be used for intravenous regional anesthesia. It has high lipid solubility: distributes more in tissues than in blood after spinal or epidural injection . Therefore less likely to reach foetus. Hence used widely in obstetrics . From Tripati 7th edition Page no 367