This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Force not acting in an enzyme substrate complex : 
Select and explain. 
A. Electrostatic, B. Covalent, C. Van der waals, D. Hydrogen
C: Van der waals
Answer: C: Van der waals 
Explanation: Vander Walls' forces are too weak, to actively paicipate in formation of enzyme- substrate complex. Forces contribute in binding are:- Hydrogen bondingQ- Ionic (electrostatic) bonding- Hydrophobic interactionEnzymes function to decrease the activation energy so that reactions can occur at normal body temperature. The substrate form a covalent bond with the enzymes active site, & accelerates the reaction.