This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Mutation in Marfan's syndrome involves? 
Select and explain. 
A. Collagen I, B. Collagen IV, C. Fibrillin I, D. Fibrillin II
C: Fibrillin I
Answer: C: Fibrillin I 
Explanation: Ans. is 'c' i.e., Fibrillin IMarfan syndrome results from inherited defect in an extracellular glycoprotein fibrillin - 1 on chromosome - 15. It has autosomal dominant inheritance.