This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Medicine
Anti-ds DNA antibodies are most specific for 
Select and explain. 
A. SLE, B. Rheumatoid ahritis, C. Scleroderma, D. Polymyositis
A: SLE
Answer: A: SLE 
Explanation: The best screening test for SLE is a demonstration of Antinuclear antibodies (ANA) Sensitive test for SLE ANA Specific test for SLE Anti-ds DNA and Anti Sm antibody Ref - Harrison's internal medicine 20e pg 2515, 2516f, 2517t, 2518t, 2522