This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Pharmacology
Allosteric enzymes show the following characteristics, except 
Select and explain. 
A. Co-operative binding of substrate, B. Obey Sigmoid saturation kinetics, C. Effector site overlap with the active site, D. Active site and effector site need not be located on the same subunit
C: Effector site overlap with the active site
Answer: C: Effector site overlap with the active site 
Explanation: In many allosteric enzymes the substrate binding site and the modulator binding site(s) are on different subunits, the catalytic (C) and regulatory (R) subunits, respectively. Co-operative binding of substrate.Obey Sigmoid saturation kinetics REF ; Katzung 12th ed.