This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Prognosis of carcinoma breast depends on 
Select and explain. 
A. Lymph node status, B. Size of tumor, C. Skin involvement, D. Peude orange
A: Lymph node status
Answer: A: Lymph node status 
Explanation: ”Metastasis to ipsilateral axillary nodes predicts outcome are surgery more powerfully than tumor size does.
The single most important predictor of 10 and 20-year survival rates in breast cancer is the number of axillary lymph nodes involved with metastatic disease.