This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Tyrosine kinase inhibitors are first line treatment in : 
Select and explain. 
A. Gastrointestinal stromal tumors, B. Receptor mediated neuroendocrine tumors, C. Breast cancer, D. Renal cell carcinoma
A: Gastrointestinal stromal tumors
Answer: A: Gastrointestinal stromal tumors 
Explanation: None