This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunology, Subject name: Microbiology
Wheal & flare reaction is what type of hypersensitivity recations? 
Select and explain. 
A. Type I, B. Type II, C. Type III, D. Type IV
A: Type I
Answer: A: Type I 
Explanation: - type I hypersensitivity reaction is IgE dependent. - it includes atopy and anaphylaxis. - wheat and flare reaction is cutaneous anaphylaxis which is type I hypersensitivity. - when a small shocking dose of an antigen is administered intradermally to a sensitised host, there will be local wheal and flare response. Reference : Anathanarayan & paniker's 9th edition, pg no: 163,164 <\p>