This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pediatrics
The karyotype of a patient with Androgen Insensitivity Syndrome is – 
Select and explain. 
A. 46 XX, B. 46 XY, C. 47 XXY, D. 45 XO
B: 46 XY
Answer: B: 46 XY 
Explanation: An individual with 'androgen insensitivity syndrome' are XY individuals (male karyotype) with a female phenotype. Mutation in the androgen receptor causes resistance to androgen action and the androgen insensitivity syndrome results.