This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Radiology
Bone scan in multiple myeloma shows – 
Select and explain. 
A. Hot spot, B. Cold spot, C. Diffusely increased uptake, D. Diffusely decreased uptake
B: Cold spot
Answer: B: Cold spot 
Explanation: There is no compensatory osteoblastic activity in multiple myeloma, therefore lesions appear as cold spot on bone scan.