This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Growth and development, Subject name: Pediatrics
Triple test for the diagnosis of Down&;s syndrome includes all of the following except: 
Select and explain. 
A. Beta hcg, B. Alpha-fetoprotein, C. Inhibin A, D. Serum oestriol level
C: Inhibin A
Answer: C: Inhibin A 
Explanation: lnhibin A is not included in Triple test , its is a pa of Quadruple test . Triple test AFP+HCG+UE3 Quadruple test Triple test+Inhibin A Combined test (first-trimester screening) PAPPA+HCG+Nuchal translucency Intergrated test First-trimester screening+Quadruple test The most sensitive is the integrated test (94-96% detection rate) The risk for abnormal offpspring for a carrier of balanced chromosomal translocation of 21:21 is 100% Ref: Nelson textbook of pediatrics 21st edition pgno: 661