This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of nucleic acids, Subject name: Biochemistry
Transcription is inhibited by 
Select and explain. 
A. Actinomycin D, B. Amanitin, C. Chloramphenicol, D. Streptomycin
A: Actinomycin D
Answer: A: Actinomycin D 
Explanation: Clindamycin -D antibiotics from StreptomycesMode of action is by inseion of phenoxa-zone ring between two G-C bp of DNA USed as anti-cancer drugRef: DM Vasudevan, 7th edition, page no: 593 table 45.2