This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Breast, Subject name: Pathology
Pagets disease except 
Select and explain. 
A. Virus association, B. Progress to chondrosarcoma, C. Less than 1% malignant, D. Ostesclerotic phase seen
C: Less than 1% malignant
Answer: C: Less than 1% malignant 
Explanation: Robbins basic pathology 9th edition page no 771,heading=clinical Course, 3rd paragraph The development of sarcoma is a dreaded but founately rare complication of paget disease occuring in only an estimated 1%of patients. The sarcoma are usually osteogenic. Paget disease is also known as Osteitis Deformans.