This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of protein and amino acid, Subject name: Biochemistry
All of the following represent disorders or protein misfolding, except 
Select and explain. 
A. Alzheimer's disease, B. Tuberculosis, C. Cystic fibrosis, D. Creutzfeldt-Jakob disease
B: Tuberculosis
Answer: B: Tuberculosis 
Explanation: A normal gene makes the normal Prp protein .when gene is mutataed there will be protein misfolding. in Alzhener&;s disease, there is beta amyloid protein formation . this fuher forms plaque . this causes dementia , hallucination etc. cystic fibrosis is caused by abnormal protein CFTR. Creutzfeldt disease is caused due to prions. tuberculosis is an infectious disease and does not cause protein misfoldingRef: DM Vasudevan - Textbook of Biochemistry, 7th edition, page no: 728 & 606