This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Anatomy
All are considered to be poor prognostic factors in liver metastasis except 
Select and explain. 
A. Synchronous lesions, B. Metachronous lesions, C. Extra-hepatic metastasis, D. CEA>200ng/ml
B: Metachronous lesions
Answer: B: Metachronous lesions 
Explanation: Poor prognostic or factors affecting outcome Four or more tumors Extra hepatic disease Size >5cm Disease free interval <1 year Lymph node positive primary lesion CEA >200ng /ml Synchronous liver metastasis Ref:Sabiston 20th edition Pgno :1464-1465