This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Central Nervous System, Subject name: Pediatrics
A newborn baby has severe facial abnormalities, as shown below. What could be the underlying CNS abnormality in this baby? 
Select and explain. 
A. Lissencephaly, B. Dandy walker malformation, C. Holoprosencephaly, D. Iniencephaly
C: Holoprosencephaly
Answer: C: Holoprosencephaly 
Explanation: c. HoloprosencephalySingle eye (cyclopia) with a tubular-shaped nose (proboscis), are usually seen in a child with Holoprosencephaly