This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Orthopaedics
Epiphyseal enlargement occurs in - 
Select and explain. 
A. Paget's disease, B. Sheurmann's disease, C. Epiphyseal dysplasia, D. Hemophilia
D: Hemophilia
Answer: D: Hemophilia 
Explanation: Epiphyseal enlargement

Most common causes of epiphyseal enlargement are chronic inflammation (e.g. JRA) or chronic increase in blood flow. Causes of Epiphyseal enlargement are:-

a) Solitary (Enlargement of particular epiphysis)

Post-inflammatory (JRA, Septic arthritis)
Perthe's disease (in repair stage)
Status post hip dislocation
Hemophilia (Hemophilic arthropathy)
Turner syndrome
Klippel-trenaunay syndrome (angiohypertrophy syndrome)
Kascibach - Merritt syndrome
Beckwith - Wiedemann syndrome (Hemihypertrophy)
Trevor disease (Dysplasia epiphysealis hemimelica)

b) Generalized

Hyperthyroidism   
Acromegaly or cerebral gigantism         
Adrenogenital syndrome   iv) Rickets
Spondyloepiphyseal dysplasia
McCune-Albright syndrome
Kniest syndrome