This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Thyroid, Subject name: Surgery
A well differentiated follicular carcinoma of thyroid can be best differentiated from a follicular adenoma by:- 
Select and explain. 
A. Huhle cell change, B. Lining of tall columnar and cuboidal cells, C. Vascular invasion, D. Nuclear features
C: Vascular invasion
Answer: C: Vascular invasion 
Explanation: Vascular invasion is best to diffrentiate between follicular carcinoma and Follicular adenoma