This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.N.S, Subject name: Medicine
Lambe Eaton syndrome is associated with 
Select and explain. 
A. Thymoma, B. Oat cell syndrome, C. Myasthenia gravis, D. Adenocarcinoma of lung
B: Oat cell syndrome
Answer: B: Oat cell syndrome 
Explanation: Lambe-Eaton myasthenic syndrome (LEMS) is a rare autoimmune disorder that is characterized by muscle weakness of the limbs. Lambe-Eaton myasthenic syndrome is caused by autoantibodies to the presynaptic membrane. Myasthenia gravis is caused by autoantibodies to the postsynaptic acetylcholine receptors.Around 60% of those with LEMS have an underlying malignancy, most commonly small cell lung cancer Ref Harrison20th edition pg 2345