This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
Coagulative necrosis is due to 
Select and explain. 
A. Denaturation of protein, B. Enzymatic digestion, C. Infection, D. None
A: Denaturation of protein
Answer: A: Denaturation of protein 
Explanation: Coagulative necrosis is a form of necrosis in which the underlying tissue architecture is preserved for at least several days. The affected tissues take on a firm texture. Presumably, the injury denatures not only structural proteins but also enzymes, thereby blocking the proteolysis of the dead cells( Robbins Basic Pathology, 9th edition, page 10 )