This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
The only thrombolytic agent approved for the treatment of acute ischemic stroke is: 
Select and explain. 
A. Tissue Plasminogen activator, B. Streptokinase, C. Urokinase, D. Pro-urokinase
A: Tissue Plasminogen activator
Answer: A: Tissue Plasminogen activator 
Explanation: Answer is A (Tissue plasmiogen Activator): Recombinant Tissue plasminogen Activator (RtPA) is the only thrombolytic agent that is approved for the treatment of acute ischaemic stroke The use of all other thrombolytics except Recombinant Tissue plasminogen activator has been stopped because of associated high rates of intracranial hemorrhage.