This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: miscellaneous, Subject name: Anatomy
Centrilobular necrosis is seen in 
Select and explain. 
A. CCL4, B. White phosphorus, C. Yellow fever, D. Eclampsia
A: CCL4
Answer: A: CCL4 
Explanation: Refer Robbins page no 872 8th edition Centrilobular necrosis refers to the necrosis of the centrilobular tissue of the hepatic lobule. The centrilobular zone of the lobule is most prone to metabolic toxins such as those generated in alcoholic hepatitis.