This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Obstetrics, Subject name: Gynaecology & Obstetrics
Drug of choice in postpaum hemorrhage resistant to oxytocin and Ergometrine: 
Select and explain. 
A. Carboprost, B. Dinoprostone, C. Dinoprost, D. Misoprostol
A: Carboprost
Answer: A: Carboprost 
Explanation: Uterotonics tried are: Oxytocin: 5 - 10 IU IV in Dilution or 40 IU/500 ml at 125 ml/hour Ergometrine: 0.2mg slow IV (Can repeat if no response) Carboprost 250 ug IM every 15 minutes, upto total 8 times Misoprostol 1000 ug rectally