This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Pharmacology
DOC for nephrogenic diabetes insipidus: 
Select and explain. 
A. Mannitol, B. Spironolactone, C. Thiazides, D. Demeclocycline
C: Thiazides
Answer: C: Thiazides 
Explanation: Ref: Goodman & Gillman's 13th ed. P 466* Nephrogenic DI may be congenital or acquired. Causes can be:# Hypercalcemia, hypokalemia, post obstructive renal failure, Li+, foscarnet, clozapine, demeclocycline, and other drugs can induce nephrogenic DI.* Thiazide diuretics reduce the polyuria of patients with DI and often are used to treat nephrogenic DI.* DOC for central diabetes insipidus: Desmopressin (V2 receptor agonist)* DOC for nephrogenic diabetes insipidus: Thiazide diuretics.* DOC for lithium induced diabetes insipidus: Amiloride