This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pharmacology
Which of the following is not an adverse effect of chronic amiodarone therapy? 
Select and explain. 
A. Pulmonary Fibrosis, B. hypothyroidism, C. hypehyroidism, D. Systemic lupus erythematosis
D: Systemic lupus erythematosis
Answer: D: Systemic lupus erythematosis 
Explanation: Impoant drugs that can cause hypothyroidism are iodides, lithium, and amiodarone. Amiodarone inhibits the peripheral conversion of T4 toT3, also interferes with thyroid hormone action and cause hypothyroidism and rarely hypehyroidism may develop on chronic use. Pulmonary alveolitis and fibrosis is the most serious toxicity of prolonged use. (REF: ESSENTIALS OF MEDICAL PHARMACOLOGY K.D TRIPATHI-6th edition...Page No-516)