This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: CNS Tumors, Subject name: Pathology
Which of the following receptor on the neuronal membrane that induces the development of glioma? 
Select and explain. 
A. CD45, B. CD133, C. CD33, D. CD24
B: CD133
Answer: B: CD133 
Explanation: Ans. (b) CD133 CD133 is used as a marker for leukaemia and glioblastoma stem cell. It is also used for identifying immature leukemic stem cell in AML and pro B leukaemia. CD45 is required for lymphocyte activation. Its deficiency causes Severe Combined immunodeficiency disease (SCID).