This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pharmacology
2nd generation sulfonylurea drugs are all except 
Select and explain. 
A. Glipizide, B. Gliclazide, C. Tolbutamide, D. Glibenclamide
C: Tolbutamide
Answer: C: Tolbutamide 
Explanation: Tolbutamide and chlorpropamide, acetohexamide are first generation sulphonylureas- cause severe hypoglycemiA 2nd gen- less hypoglycemia- gliclazide, glipizide, glibenclamide etc (REF.Essential of medical pharmacology K D TRIPATHI 6 Edition, Page No - 266)