This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
DOC for acute organophosphate poisoning is: 
Select and explain. 
A. Neostigmine, B. Atropine, C. Pilocarpine, D. Tubocurarine
B: Atropine
Answer: B: Atropine 
Explanation: Atropine  
It is highly effective in counteracting the muscarinic symptoms, but higher doses are required to antagonize the central effects. It does not reverse peripheral muscular paralysis which  is a nicotinic  action.  
All cases of anti-ChE  (carbamate or organophosphate) poisoning must be promptly given atropine 2 mg i.v. repeated every 10 min till dryness of mouth or other signs of atropinization appear (upto 200 mg has been administered in a day). Continued treatment with maintenance doses may be required for 1- 2  weeks. 
Reference: Essentials of Medical Pharmacology Eighth Edition KD  TRIPATHI  page no 122,123