This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
Prominent stimulus for release of secretin is : 
Select and explain. 
A. Acidity of chyme, B. Distention of duodenum, C. Composition of food, D. None
A: Acidity of chyme
Answer: A: Acidity of chyme 
Explanation: A i.e. Acidity of chime