This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti Microbial, Subject name: Pharmacology
Drug which shows concentration dependent killing: 
Select and explain. 
A. Aminoglycosides, B. Azithromycin, C. Beta lactam, D. Chloramphenicol
A: Aminoglycosides
Answer: A: Aminoglycosides 
Explanation: Ans. A. AminoglycosidesSome of the antibiotics show efficacy when their levels are maintained at higher concentration. Aminoglycosides, fluoroquinolones and metronidazole are concentration dependent drugs. Other type is time dependent killing where concentration should be above MIC as long as possible, beta lactam and vancomycin show time dependent killing.