This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Metabolism of nucleic acids, Subject name: Biochemistry
Lesh Nyhan syndrome is associated with deficiency of 
Select and explain. 
A. HGP (paial), B. HGP (total), C. PRPP (paial), D. PRPP (total)
B: HGP (total)
Answer: B: HGP (total) 
Explanation: REF :DM VASUDEVAN TEXTBOOK :7th EDITION ;Page no :403 Disease deficient enzyme GPD Deficiency G6PD Gaucher's disease beta glucosidase Lesch-Nyhan syndrome HGPase