This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General pathology, Subject name: Pathology
Increased susceptibility to breast cancer is likely to be associated with a mutation in the following gene- 
Select and explain. 
A. P53, B. BRCA-1, C. Retinoblastoma(Rb), D. H-Ras
A: P53
Answer: A: P53 
Explanation: Reference :Robbins basic pathology 9th edition pg no 186:BRCA1, BRCA2 Breast and ovarian tumors