This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Apoptosis, Subject name: Pathology
Arrange the steps in apoptosis in sequence of occurrence: 1. Release of cyt c in cytoplasm2. Activation of APAF-13. Removal of BCL-2 4. Caspase activation 
Select and explain. 
A. 3-1-2-4, B. 4-2-1-3, C. 1-2-4-3, D. 3-2-4-1
A: 3-1-2-4
Answer: A: 3-1-2-4 
Explanation: Intrinsic Pathway of Apoptosis:- Apoptosis causes fragmentation of DNA, which gives Step-Ladder pattern on DNA gel electrophoresis.