This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Microbiology
Lethal effect of dry heat is due to ? 
Select and explain. 
A. Denaturation of proteins, B. Oxidative damage, C. Toxicity due to metabolites, D. All of the above
D: All of the above
Answer: D: All of the above 
Explanation: Ans. is 'd' i.e., All of the above HEAT STERILIZATION Heat is the most reliable method of sterilisation and should be the method of choice unless contraindicated. o Sterilization by heat is of two types. Dry heat Killing effect is due to protein denaturation, oxidative damage and the toxic effect of elevated metabolites.