This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pharmacology
Acute Gouty ahritis is seen early in treatment following 
Select and explain. 
A. Probenecid, B. Allopurinol, C. Colchicine, D. Rasburicase
B: Allopurinol
Answer: B: Allopurinol 
Explanation: Allopurinol REF: Goodman Gillman manual of pharmacology and therapeutics 2008 edition page 458 "The incidence of acute attacks of gouty ahritis mayincrease duringthe early months of allopurinol therapy as a consequence of mobilization of tissue stores of uric acid. Co-administration of colchicine helps suppress such acute attacks. After reduction of excess tissue stores of uric acid, the incidence of acute attacks decreases and colchicine can be discontinued"