This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Liddle syndrome is characterized by 
Select and explain. 
A. Hypokalemic metabolic alkalosis with hypotension, B. Hypokalemic metabolic alkalosis with hypertension, C. Hyperkalemic metabolic acidosis with hypotension, D. Hyperkalemic metabolic acidosis with hypertension
B: Hypokalemic metabolic alkalosis with hypertension
Answer: B: Hypokalemic metabolic alkalosis with hypertension 
Explanation: Liddle syndrome is an autosomal dominant disorder  with genetic defect(gain of function mutation) in collecting tubules sodium channel, resulting in increased tubular sodium reabsorption.