This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Hematology, Subject name: Pharmacology
Anti-coagulant of choice for heparin induced thrombo.. Cytopenia is? 
Select and explain. 
A. Lepirudin, B. Aprotinin, C. Abciximab, D. Plasminogen
A: Lepirudin
Answer: A: Lepirudin 
Explanation: Lepirudin is a parenterally acting direct thrombin inhibitor. They inactivate fibrin bound thrombin in their clots since their activity is independent of antithrombin III. It&;s use has been approved in HIT. From medical pharmacology padmaja 4th edition Page no 338