This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cardiovascular system, Subject name: Pharmacology
Which of the following drug has been withdrawn from the market? 
Select and explain. 
A. Nicorandil, B. Ropinrole, C. Rotigotine, D. Rofecoxib
D: Rofecoxib
Answer: D: Rofecoxib 
Explanation: COXIBS which are selective cox 2 inhibitors are very rarely used and banned from the market due to the high incidence of Myocardial infarction and stroke. these disrupt the ration of TXA2 and PCI thromboxane and prostacycline which leads to long term risk of stroke. Ref: KD Tripathi 6th ed, pg 534 and 197