This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Intestinal Polyps, Colon & Anal Cancer, Subject name: Pathology
Mucosal melanosis and hamaomatous polyps are seen in? 
Select and explain. 
A. Peutz-Jeghers syndrome, B. Cronkhite Canada syndrome, C. Familial adenomatous polyposis, D. Hereditary non polyposis colonic cancer
A: Peutz-Jeghers syndrome
Answer: A: Peutz-Jeghers syndrome 
Explanation: Peutz-jeghers syndrome: Autosomal dominant disorder Mutation- STK 11 / LKB1 gene Multiple gastrointestinal hamaomatous polyps + Mucocutaneous hyperpigmentation Increased risk for colon, pancreas, breast, lung, ovaries, uterus, testes neoplasms Gross- Polyps are large & pedunculated with lobulated contour.