This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
DNA restriction fragments are separated by ? 
Select and explain. 
A. Paper chromatography, B. Agarose gel electrophoresis, C. Thin-layer chromatography, D. Ultracentrifugation
B: Agarose gel electrophoresis
Answer: B: Agarose gel electrophoresis 
Explanation: Ans. is 'b' i.e., Agarose gel electrophoresis DNA is cut into large fragments, using restriction enzymes. These fragments are then separated by gel electrophoresis (either agarose or polyacrylamide gel electrophoresis).