This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
All are true about basal cell carcinoma except 
Select and explain. 
A. It is locally aggressive  tumour, B. They are slow growing and rarely metastasize, C. Associated with mutations that activate Hedgehog pathway signalling, D. Most common site is acral parts
D: Most common site is acral parts
Answer: D: Most common site is acral parts 
Explanation: Basal cell carcinoma -most common site involved is face, It is the most common invasive skin cancer in human being.