This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Psychiatry
In Alzheimer's disease, the pathology seen in the brain is - 
Select and explain. 
A. Atrophy of parietal and temporal lobes, B. Atrophy of temporal lobes, C. Atrophy of temporal and occipital lobes, D. Atrophy of parietal and occipital lobes
A: Atrophy of parietal and temporal lobes
Answer: A: Atrophy of parietal and temporal lobes 
Explanation: Ans. is 'a' i.e., Atrophy of parietal and temporal lobesGross pathology in Alzhiemer's disease:o Diffuse cerebral atrophy of the hippocampus, amygdala and entorhinal coex.o Enlargement of the ventricles caused by neuronal loss.Grossly the brain shows a variable degree of coical atrophy marked by widening of the cerebral sulci.These changes are most pronounced in the temporal and parietal lobes: Frontal lobes can also be involved.