This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Autosomal recessive polycystic kidney disease is characterised by the altered expression of: 
Select and explain. 
A. Polycystin, B. Nephrocystin, C. Uromodulin, D. Fibrocystin
D: Fibrocystin
Answer: D: Fibrocystin 
Explanation: Fibrocystin (polyductin) gene mutation is seen in autosomal recessive polycystic kidney disease. Note: Polycystin mutation is associated with autosomal dominant polycystic kidney disease. Nephrocystin is related to nephronophthisis. Uromodulin mutation is seen in medullary cystic kidney disease. Ref: Harrisons principles of internal medicine, 18th edition, Page: 2356.