This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Investigation of choice to establish the diagnosis in case of nephrotic syndrome in adult is 
Select and explain. 
A. Renal biopsy, B. DMSA, C. CT Scan, D. MRI
A: Renal biopsy
Answer: A: Renal biopsy 
Explanation: Answer- A. Renal biopsyIn adults since steroid responsive disease is less likely (<30%), and a wide differential diagnosis ofnephrotic syndrome exists, renal biopsy is recommended to establish the diagnosis.