This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General Surgery, Subject name: Surgery
The occurrence of hypothyroidism following administration of supplemental iodine to subjects with endemic iodine deficiency goiter is known as: 
Select and explain. 
A. Jod-Basedow effect, B. Wolff-Chaikoff effect, C. Rafetoff Syndrome, D. Pendred Syndrome
B: Wolff-Chaikoff effect
Answer: B: Wolff-Chaikoff effect 
Explanation: Wolf-Chaikoff effect Iodine induced hypothyroidism Jod-Basedow's effect Iodine induced hypehyroidism PENDRED SYNDROME Congenital sensorineural hearing loss + Goitre Gene is located on chromosome no.7q(long arm) RAFETOFF SYNDROME End organ resistance to T4