This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Inflammation, Subject name: Pathology
Cytokine having pyrogenic activity is:- 
Select and explain. 
A. TGF-beta, B. IL-6, C. IL-5, D. IL-2
B: IL-6
Answer: B: IL-6 
Explanation: Cytokines responsible for development of fever IL -1 IL-6 TNF alpha CNTF (ciliary neurotrophic factor) Interfer on alpha IL -18 is not responsible for causing fever