This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
The major determinant for the rate of cerebral blood flow is: 
Select and explain. 
A. Intracranial pressure, B. Aoic blood pressure, C. Aerial PaCO2, D. Neurogenic regulation
A: Intracranial pressure
Answer: A: Intracranial pressure 
Explanation: Factors affecting overall cerebral blood flow include: Intracranial pressure Local constriction & dilation of cerebral aerioles Mean aerial pressure at brain level Viscosity of blood Mean venous pressure at brain level