This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Skin
A 23-yeard-old college student has asympt-omatic and hyperpigmented macules on both palms for three weeks. The most appropriate diagnostic test is: 
Select and explain. 
A. Veneral Diseases research Laboratory (VDRL) test, B. Skin biopsy, C. Serum coigol levels, D. Assay for arsenic in skin, hair & nails
A: Veneral Diseases research Laboratory (VDRL) test
Answer: A: Veneral Diseases research Laboratory (VDRL) test 
Explanation: A i.e. Veneral Disease Laboratory (VDRL) Estimation of coisol levels are not indicated as only skin lesions without other symptoms is disouring adrenal pathology. Assay of arsenic is not required as arsenic poisoining will always present with systemic symptoms. Skin biopsy is not indicated as only presentation is hyperpigrnented macules. So the answer is straight forward - As secondary syphilis usually presents with B/L symmetrical So the answer is straight forward - As secondary syphilis usually presents with B/L symmetrical