This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Anti-Ulcer, Subject name: Pharmacology
Proton pump inhibits are used in management of - 
Select and explain. 
A. Insulinoma, B. GERD, C. Stress ulcer & gastritis, D. All of the above
D: All of the above
Answer: D: All of the above 
Explanation: Ans. is 'd' i.e., All of the above o PPI are the DOC for peptic ulcer (gastric or duodenal), GERD, ZE syndrome, prevention of aspiratory pneumonia and NSAID induced gastric / duodenal ulcers. Note - PGE1 analogue (Misoprostol) is a specific drug for prevention and treatment of NSAID induced ulcer, but DOC is PPI.