This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Dental
Which layer of skin causes vesicular change in case of burn – 
Select and explain. 
A. Basal layer, B. Papillary layer, C. Epidermis, D. Dermis
D: Dermis
Answer: D: Dermis 
Explanation: First degree burns involve epidermis, but it causes erythema (not blister).
Second degree burns involve dermis and forms subepidermal blisters.