This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Genetic and genetic disorders, Subject name: Pediatrics
Multifactorial inheritance is most likely to play a significant role in the appearance of : 
Select and explain. 
A. Achondroplasia, B. Lysosomal storage disease, C. Cleft lip, D. Huntington disease
C: Cleft lip
Answer: C: Cleft lip 
Explanation: Multifactorial inheritance plays a significant role in the appearance if cleft lip. Multifactorial Inheritance: Refers to traits that are caused by a combination of inherited, environmental, and stochastic factors These include the following: Children (Congenital malformation) Adult Pyloric stenosis Neural tube defects Congenital hea defects Congenital dislocation of hip Cleft lip and cleft palate Diabetes mellitus Hypeension Coronary hea disease Gout Schizophrenia Ref: Nelson textbook of pediatrics 21st edition pgno: 652