This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocarditis, Subject name: Pathology
Most friable vegetation is seen in: 
Select and explain. 
A. Infective endocarditis, B. Libman Sacks endocarditis, C. Rheumatic hea disease, D. Rheumatoid hea disease
A: Infective endocarditis
Answer: A: Infective endocarditis 
Explanation: The hallmark of infective endocarditis is the presence of friable, bulky and potentially destructive vegetations containing fibrin, inflammatory cells and bacteria or other organisms on the hea valves.