This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: C.V.S, Subject name: Medicine
True regarding Barrett's oesophagus is 
Select and explain. 
A. Benign course, B. Premalignant condition, C. Squamous metaplasia of lower esophagus, D. Medical treatment is useful in preventing malignancy
B: Premalignant condition
Answer: B: Premalignant condition 
Explanation: Barrett's oesophagus is a metaplastic change in the lining mucosa of the oesophagus in response to chronic gastroesophageal reflux. The hallmark of 'specialised' Barrett's epithelium is the presence of mucus-secreting goblet cells (intestinal metaplasia).High-dose PPI treatment or an antireflux operation, these endoscopic ablation methods can result in a neosquamous lining. But there is no evidence yet that any of these methods are reliable in eliminating cancer risk.Bailey and love 26th edition PG: 1000