This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: General Microbiology (Sterilization and Bacterial Genetics), Subject name: Microbiology
Following are least susceptible to disinfectants and antiseptics? 
Select and explain. 
A. Spore, B. Protozoa, C. Prions, D. Fungi
C: Prions
Answer: C: Prions 
Explanation: Protozoa, spores and fungi can be killed by autoclaving, hot air oven, gamma radiation or chemisterilants like Cidex, ethylene oxide or plasma. Prions Most resistant to disinfectants and antiseptics Resistant to dry heat, proteases, gamma radiation or chemisterilants like Cidex, ethylene oxide or plasma. Killed by autoclaving for 18 minutes at a temperature of 134deg C or 20-40% sodium hypochlorite.