This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Surgery
All of the following are true for patients with ulcerative colitis associated with primary sclerosing cholangitis (PSC), Except 
Select and explain. 
A. The may develop biliary cirrhosis, B. May have raised alkaline phosphatase, C. Increased risk of hilar Cholangiocarcinoma, D. PSC reves after a total colectomy
D: PSC reves after a total colectomy
Answer: D: PSC reves after a total colectomy 
Explanation: PSC associated with ulcerative colitis eventually leads to biliary cirrhosis. Investigations reveal a cholestatic pattern in LFT with an elevation of serum alkaline phosphatase & gamma-glutamyltransferase. The prevalence of cholangiocarcinoma in patients with PSC ranges from 7 to 13%. Reference: Bailey & love&;s sho practice of surgery,25th edition, page no:1127; SRB&;s manual of surgery,5th edition, page no:658.