This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Physiology
False about Gaucher's disease 
Select and explain. 
A. Beta Glucocerebrosidase defective, B. Cherry red spots on fundoscopy, C. Erlenmeyer's flask deformity, D. Tarate resistant acid phosphatase -ve
D: Tarate resistant acid phosphatase -ve
Answer: D: Tarate resistant acid phosphatase -ve 
Explanation: Three biochemical markers of gaucher disease Angiotensin-conveing enzyme ( ACE ) Tarate-resistant acid phosphate ( TRAP ) Chitotriosidase ( CHITO ) These marker are elevated in active disease, these are useful indicators of disease progress and response to enzyme replacement therapy So gaucher disease is basically Tarate-resistant acid phosphatase positive as the disease is being treated the levels of TRAP gradually declines