This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Kidney, Subject name: Pediatrics
Best method of estimation of amount of proteinuria in a 2 year child with nephrotic syndrome is 
Select and explain. 
A. Dipstick testing, B. 24 hr urine protein, C. Spot urine sample for protein/creatinine ratio, D. Microalbuminuria
C: Spot urine sample for protein/creatinine ratio
Answer: C: Spot urine sample for protein/creatinine ratio 
Explanation: c. Spot urine sample for protein/creatinine ratio(Ref: Nelson 20/e 2518)Though 24 hr urine for protein and creatinine, is more accurate, but due to difficulty in collecting 24 hour urinary sample in children, Spot urine sample for protein/creatinine ratio is preferred.