This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Misc. (W.B.C), Subject name: Pathology
Which of the following represents the marked area in the histology of lymph node? 
Select and explain. 
A. Mantle zone, B. Marginal zone, C. Paracortical area, D. Germinal centre
A: Mantle zone
Answer: A: Mantle zone 
Explanation: Ans. (a) Mantle zone(Ref: R 9/p 583)A normal lymph node has 2 areas: Cortex - Lymphoid follicles and paracortical areas, Medulla - predominantly blood vesselsStructures in a FollicleGerminal center: Round/oval zone containing pale staining cells, surrounded by darker cellsMantle zone: Small dark coloured unchallenged B cells surrounding pale staining germinal centersMarginal zone: Light zone surrounding follicles; contains postfollicular memory B cells derived after stimulation of recirculating cells from T cell dependent antigen; named "marginal cells" due to location