This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: G.I.T, Subject name: Anatomy
Commonest association seen in carcinoma Gallbladder 
Select and explain. 
A. Peritoneal deposits, B. Duodenal infiltration, C. Secondaries to liver, D. Cystic node involvement
C: Secondaries to liver
Answer: C: Secondaries to liver 
Explanation: Metastasis in Carcinoma Gallbladder Direct hepatic invasion :59% cases Lymph node metastasis : 45%cases Perineural invasion: 42% cases Ref: Sabiston 20th edition Pgno : 1512-1514