This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: All India exam, Subject name: Physiology
Intraepidermal blister formation is seen in 
Select and explain. 
A. Pemphigus Vulgaris, B. Pemphigoid, C. Dermatitis herpetiformis, D. None of the above
A: Pemphigus Vulgaris
Answer: A: Pemphigus Vulgaris 
Explanation: Pemphigus vulgaris a. Blisters in pemphigus vulgaris are wiraepidermal while those in bullous pemphigoid are subepidermal. b. Typical acantholytic (Tzanck) cells are seen in pemphigus vulgaris but not in bullous pemphigoid. c. Nikolsky 's sign is positive in pemphigus vulgaris but not in bullous pemphigoid.