This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Irreversible cell Injury/Necrosis, Subject name: Pathology
Electron microscopy finding indicating irreversible cell injury is: 
Select and explain. 
A. Dilation of ER, B. Dissociation of ribosomes from rough ER, C. Flocculent densities in the mitochondria, D. Intact cell membrane
C: Flocculent densities in the mitochondria
Answer: C: Flocculent densities in the mitochondria 
Explanation: Irreversible injury is associated morphologically with:- Mitochondrial swelling Plasma membrane damage which forms myelin figures Lysosomal swelling. Large, flocculent, amorphous densities develop in the mitochondrial matrix