This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
What is the enzymatic defect which causes Hunter's Disease? 
Select and explain. 
A. a) L- Iduronidase, B. b) Iduronate sulphatase, C. c) Beta Galactosidase, D. d) All of the above
B: b) Iduronate sulphatase
Answer: B: b) Iduronate sulphatase 
Explanation: Explanation- Inheritence- X-linked Recessive Defective enzyme- Iduronate Sulphatase Clinical Features- slower progression of somatic and central nervous system (CNS) deterioration large tongue prominent forehead joint stiffness sho stature skeletal dysplasia obstructive airways Valvular hea disease Mental retardation