This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
Metabolic derangements in severe burns are all except 
Select and explain. 
A. Tcoico steroid secretion, B. Hyperglycaemia, C. Tsecretion of HC1, D. Neutrophil dysfunction
C: Tsecretion of HC1
Answer: C: Tsecretion of HC1 
Explanation: Answer is 'c' i.e. T secretion of HC1 Increased HCI secretion is not seen in burn injury. - Stress ulcers (Curling's ulcer) seen in burns are thought to be due to decrease in mucosal defence mechanism (not increase in acid secretion) Effect of burn on Immune system - Burns cause a global depression in immune function. There is depressed cellular function in all pas of the immune system, including activation and activity of neutrophils macrophages, T lymphocytes, and B lymphocytes. Thus the burned patients are at great risk for a number of infections complication. Effect of burn injury on metabolism Burn injury leads to release of catabolic hormones like catecholamines, coicosteriods, glucagons etc. These lead to a hypermetabolic state.