This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
A 20 year old female was diagnosed with granulose cell tumor of the ovary. Which of the following bio markers
would be most useful for follow-up of patient? 
Select and explain. 
A. Inhibin, B. CA50, C. CA 19-9, D. Neuron – specific enolase
A: Inhibin
Answer: A: Inhibin 
Explanation: Granulosa cell tumor
• The most common type of ovarian tumor that is composed of cells that stain positively with inhibin.
• Histologically, the cells may form Call-Exner bodies
• The tumor cells may secrete estrogens and cause precocious sexual development in girls or increase the risk for endometrial hyperplasia and carcinoma in women.
• Less commonly granulosa cell tumors can secrete androgens and produce masculinization.