This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Ophthalmology
Cobblestone appearance of conjunctiva is seen in: March 2012 
Select and explain. 
A. Bacterial conjunctivitis, B. Spring catarrh, C. Ophthalmia neonatorum, D. Trachoma
B: Spring catarrh
Answer: B: Spring catarrh 
Explanation: Ans. B i.e. Spring catarrh Conditions affecting conjunctiva In bacterial conjunctivitis, the picture of hyperaemia is associated with a mucus discharge, which gums the lids together, paicularly in the mornings because of the accumulation during the night On eveing the upper eyelid, the palpebral conjunctiva is seen to be hyperophied & mapped out into polygonal raised areas, not unlike cobblestones in vernal conjunctivitis/spring catarrh In ophthalmia neonatorum, the conjunctiva becomes intensely inflamed, bright red & swollen, with a thick yellow pus discharge The essential lesion of trachoma is a trachomatous follicle