This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Cell Wall Synthesis Inhibitors, Subject name: Pharmacology
The drug that should be used for prophylaxis of close contacts of a patient suffering from meningococcal meningitis is: 
Select and explain. 
A. Rifampicin, B. Dapsone, C. Erythromycin, D. Amikacin
A: Rifampicin
Answer: A: Rifampicin 
Explanation: - Rifampicin, ceftriaxone and ciprofloxacin are used for the prophylaxis of meningococcal meningitis. - Ceftriaxone is most effective drug for prophylaxis of meningococcal meningitis, however it is injectable drug. - Resistance to rifampicin has been repoed in many meningococci, so it is not preferred these days. - The drug of choice for prophylaxis of meningococcal meningitis should be chosen as Ciprofloxacin > Rifampicin > Ceftriaxone