This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Amyloidosis is associated with all of the following except: March 2012 
Select and explain. 
A. Multiple myeloma, B. Renal failure, C. Alzheimer's disease, D. Acute inflammatory conditions
D: Acute inflammatory conditions
Answer: D: Acute inflammatory conditions 
Explanation: Ans: D i.e. Acute inflammatory conditions Amyloidosis In many cases of primary amyloidosis, the patients have some form of plasma cell dyscrasia. Best defined is the occurrence of systemic amyloidosis in 5% to 15% of individuals with multiple myeloma, a plasma cell tumour characterized by multiple osteolytic lesions throughout the skeletal system Patients on long term hemodialysis for renal failure develop amyloidosis as a result of deposition of beta-2 microglobulin. Alzheimer's disease may cause systemic senile amyloidosis/localized amyloidosis At one time, TB, Bronchiectasis and chronic osteomyelitis were the most impoant underlying conditions for reactive systemic amyloidosis. More commonly now, reactive systemic amyloidosis complicates rheumatoid ahritis, other connective tissue disorders such as ankylosing spondylitis, and inflammatory bowel disease (Crohn disease and Ulcerative colitis).