This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Physiology
Which of the following acts as the major neurotransmitter in substantia nigra 
Select and explain. 
A. Dopamine, B. Noradrenaline, C. Acetylcholine, D. Serotonin
A: Dopamine
Answer: A: Dopamine 
Explanation: In substantia nigra, dopamine is the major neurotransmitter.