This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Medicine
All are associated with MEN-2 except - 
Select and explain. 
A. Pheochromocytoma, B. Islet cell hyperplasia, C. Medullary carcinoma thyroid, D. Parathyroid adenoma
B: Islet cell hyperplasia
Answer: B: Islet cell hyperplasia 
Explanation: MEN type 2 (MEN 2), which is also called Sipple's syndrome, is characterized by the association of medullary thyroid carcinoma (MTC), pheochromocytomas, and parathyroid tumors. Three clinical variants of MEN 2 are recognized: MEN 2A, MEN 2B, and MTC only. Reference : page 2340 Harrison's Principles of Internal Medicine 19th edition