This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Physiology
Ovulation in women with 28-day cycle occurs at 
Select and explain. 
A. 14 days prior to mensturation, B. Just before LH surge, C. Just after corpus leuteal maturation, D. Due to progesterone rise
A: 14 days prior to mensturation
Answer: A: 14 days prior to mensturation 
Explanation: Ovulation is the release of egg from the ovaries. In humans, this event occurs when the de Graaf&;s follicles rupture and release the secondary oocyte ovarian cells. After ovulation, during the luteal phase, the egg will be available to be feilized by sperm. In addition, the uterine lining (endometrium) is thickened to be able to receive a feilized egg. If no conception occurs, the uterine lining, as well as blood, will be shed during menstruation.In humans, ovulation occurs about midway through the menstrual cycle, after the follicular phase. The few days surrounding ovulation (from approximately days 12 to 16 of a 28-day cycle)Ref: Ganong&;s review of medical physiology; 24th edition; page no:-401