This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous (Bio-Chemistry), Subject name: Biochemistry
Mutation in the oxidative enzymes could lead to: 
Select and explain. 
A. Zellweger's syndrome, B. Gaucher's disease, C. Epidermolysis bullosa, D. Leber's neuropathy
A: Zellweger's syndrome
Answer: A: Zellweger's syndrome 
Explanation: Ans. A. Zellweger's syndromePeroxisome biogenesis disorders are a group of diseases involving the enzyme activities of peroxisomes. The most severe form is Zellweger's syndrome characterized by the absence of functional peroxisomes.