This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Virology (General Propeies, DNA Viruses), Subject name: Microbiology
Owl eye appearance of infected cell is caused by- 
Select and explain. 
A. Variola virus, B. Rabies, C. Polio, D. CMV
D: CMV
Answer: D: CMV 
Explanation: Owl eye appearance is caused by Cytomegalovirus (CMV) which Belongs to Betavirinae (HHV5). Inclusion bodies, are nuclear or cytoplasmic aggregates of stable substances, usually proteins. They typically represent sites of viral multiplication in a bacterium or a eukaryotic cell and usually consist of viral capsid proteins. Option 1: Variola virus-Paschen bodies Option 2: Rabies- Negri bodies Option 3: Polio -Cowdry type B inclusions