This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: FMGE 2018, Subject name: Medicine
Refractory Septic shock is defined as? 
Select and explain. 
A. Shock persisting > 1 hour after IVF administration, B. Shock persisting > 1 hour after IVF administration and high dose vasopressors, C. Shock that is refractory to medical treatment, D. Shock that does not improve despite treatment for 24 hours
B: Shock persisting > 1 hour after IVF administration and high dose vasopressors
Answer: B: Shock persisting > 1 hour after IVF administration and high dose vasopressors 
Explanation: Septic Shock Sepsis with hypotension despite adequate fluid resuscitation for atleast 1 hr, with perfusion abnormalities. or Need of vasopressors to maintain the blood pressure Refractory Septic Shock Septic shock that last for 1 hour and does not respond to fluid or pressor administration.