This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Urology, Subject name: Surgery
The neo-adjuvant chemotherapy indicated in oesophageal carcinoma 
Select and explain. 
A. Cisplatin, B. Doxorubicin, C. Mitomycin C, D. 5-FU-Leucovarin
A: Cisplatin
Answer: A: Cisplatin 
Explanation: Treatment of CA esophagus High-grade dysplasia (Tis) or T1a Endoscopic mucosal resection Localised advanced cancer T1: Vagal sparing or transhiatal or minimal invasive esophagectomy with limited LN dissection T2 and T3: Neoadjuvant Chemoradiation + surgery Cervical SCC or Non-ideal candidate for resection : Definitive chemoradiation Locally advanced cancer Chemoradiation (+- surgical resection in T4a) Metastatic disease Definitive chemoradiation (for involved distant LN or metastatic disease) Malignant TEF Coated SEMS (Self expanding metallic stents) Chemotherapy regimen : Epirubicin + Cisplatin + 5-FU Ref: Shackelford 7th edition Pgno : 438-448