This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Retina, Subject name: Ophthalmology
Which of the following is not a High Risk Characteristic in proliferative diabetic retinopathy 
Select and explain. 
A. NVD >= 1/3 - 1/2 disc area, B. NVD + Vitreous or Preretinal haemorrhage, C. NVE >= 1/2 disc area and Preretinal or Vitreous haemorrhage, D. NVD + Clinically signifacnt macular edema
D: NVD + Clinically signifacnt macular edema
Answer: D: NVD + Clinically signifacnt macular edema 
Explanation: Proliferative Diabetic Retinopathy Early PDR- Presence of new vessels High risk PDR NVD >= 1/3 - 1/2 disc area or NVD and Vitreous or Preretinal haemorrhage or NVE >= 1/2 disc area and Preretinal or Vitreous haemorrhage