This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Immunology, Subject name: Microbiology
Super antigen acts through? 
Select and explain. 
A. IL-3, B. IL-6, C. IFN-Gamma, D. IL_1 & TNF
D: IL_1 & TNF
Answer: D: IL_1 & TNF 
Explanation: Superantigens are ceain protein molecules such as staphylococcal enterotoxin, that stimulate large numbers of T cells irrespective of antigenic specificity. This leads to an excessive and dysregulated immune response with release of cytokines such as interleukin-1,2 and tumor necrosis factor and interferon gamma. Reference : Anathanarayan & paniker's 9th edition, pg no:90,203 <\p>