This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Surgery
The mechanism of action by which pyrantel pamoate is effective for the treatment of Necator americanus (hookworm) disease is. 
Select and explain. 
A. Interference with cell-wall synthesis, B. Interference with cell division, C. Inhibition of neuromuscular transmission, D. Depletion of membrane lipoproteins
C: Inhibition of neuromuscular transmission
Answer: C: Inhibition of neuromuscular transmission 
Explanation: Pyrantel pamoate is an antihelminthic that acts primarily as a depolarizing neuromuscular blocker. In ceain worms, a spastic neuromuscular paralysis occurs, resulting in the expulsion of the worms from the intestinal tract of the host. Pyrantel also exes its effect against parasites release of acetylcholine andinhibition of cholinesterase.