This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Pathology
Best marker of SLE is? 
Select and explain. 
A. Anti-La, B. Anti Sm antibodies, C. Anti-ds DNA antibodies, D. Anti-Histone antibodies
C: Anti-ds DNA antibodies
Answer: C: Anti-ds DNA antibodies 
Explanation: “Anti-ds DNA antibodies are the most specific marker of SLE”
ANTINUCLEAR ANTIBODY (ANA) PATTERNS AND CLINICAL ASSOCIATIONS