This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Thyroid and Parathyroid, Subject name: Pathology
RET gene mutation is associated with which malignancy - 
Select and explain. 
A. Pheochromocytoma, B. Medullary carcinoma thyroid, C. Lymphoma, D. Renal cell carcinoma
B: Medullary carcinoma thyroid
Answer: B: Medullary carcinoma thyroid 
Explanation: Ans. is 'b' i.e., Medullary carcinoma thyroid o RET p ratoon cumene is a growth factor receptor (receptor tyrosine kinase)o The RET protein Is a receptor for the glial cell lined derived neurotrophic factor and structurally related proteins that promote cell survival during neural development.