This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Substance abuse, Subject name: Anatomy
Amotivation syndrome caused by 
Select and explain. 
A. Cannabis abuse, B. Opioid abuse, C. Alcohol abuse, D. Heroin abuse
A: Cannabis abuse
Answer: A: Cannabis abuse 
Explanation: Psychiatric presentation---------------------Mimics panic attacks Patient on intoxication has increased activation of sympathetic nervous system Gate way drug This drug is called gate way drug as when a person uses this drug, he has a chance of increased exposure to other drugs Amotivation syndrome Patient with amotivation syndrome will lack of drive, abulia, no motivation for any activities hemp insanity insanity caused by cannabis is called hemp insanity if a person with family history of psychosis takes cannabis there is a chance a kindling of psychotic symptoms Ref.kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no.645