This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Infectious disease, Subject name: Pediatrics
Initial manifestation as an infection of the limbic regions of the brain is seen in children with the following infection ? 
Select and explain. 
A. Enterovirus, B. Rabies, C. Epstein-Barr virus, D. Cytomegalovirus
B: Rabies
Answer: B: Rabies 
Explanation: Rabies has 2 principal forms. Encephalitic or "furious" rabies begins with nonspecific symptoms, including fever, sore throat, malaise,headache,nausea and vomiting and weakness. These are accompanied by paresthesias and pruritus at or near bite site that extend along the affected limb. Then the patient stas showing typical symptoms of severe encephalitis, with agitation, depressed mentation, and occasionally seizures. Characteristically patients with rabies encephalitis initially have periods of lucidity intermittent with periods of profound encephalopathy. Reference : Nelson textbook of pediatrics 19th edition Page 1155