This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Anaesthesia
Laryngeal spasm induced during intubation can be prevented by the following drugs except – 
Select and explain. 
A. Fentanyl, B. Local anesthetic spray, C. Rofecoxib, D. Diltiazem
C: Rofecoxib
Answer: C: Rofecoxib 
Explanation: Reflex response (bronchospasm, laryngospasm, ↑ BP, ↑ HR) can be blunted by:- adequate depth of anaesthesia, opioids (Fentanyl, sufentanil), IV lignocaine, Local xylocaine spray, β-blocker (esmolol), Calcium channel blocker (e.g. diltiazem).