This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Blood, Subject name: Medicine
Feature of Sickle cell trait? 
Select and explain. 
A. Anemia, B. Bony Pain, C. Dactylitis, D. Isosthenuria
D: Isosthenuria
Answer: D: Isosthenuria 
Explanation: Ans. D. IsosthenuriaSickle cell traita. Heterozygous for sickle cell genes (AS)b. They have normal hematological picture with normal MCV and no anemiac. Only significant manifestation is decrease renal concentration ability presenting with isosthenuria and hematuriad. UTI is more commone. With hypoxia (as in scuba diving) venous thrombosis especially splenic vein can occurf. No treatment neededg. Sickle cell trait have protective effect for plasmodium infection.Hb sickle cell diseasea. Mild version of sickle cell disease with fewer crisesb. Visual disturbance is commonc. Painful crisis do not occurd. Renal feature includesi. isosthenuriaii. hematuriaiii. UTIiv. No treatment needed