This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Congenital Anomalies of the CNS, Subject name: Pediatrics
Administration of which of the following can prevent neural defects in newborn? 
Select and explain. 
A. Folic acid, B. VitBl'2, C. Pyridoxine, D. Vitamin C
A: Folic acid
Answer: A: Folic acid 
Explanation: Ref: Nelson's Textbook of Pediatrics. 19th Edition.Explanation:Prevention of Neural tube defectsAll women of childbearing age and who are capable of becoming pregnant take (1.4 mg of folic acid daily.In high-risk women (previously affected child), supplementation should be started with 4 mg of folic acid daily, beginning i mo before the time of the planned conception.Certain drugs that antagonize folic acid increase the risk of myelomeningoceleTrimethoprimCarbamazepinePhenytoinPhenobarbitalPrimidoneValproic acid