This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Miscellaneous, Subject name: Medicine
Which one of the following statement is true about Dipivefrine? 
Select and explain. 
A. It is not a prodrug, B. It causes vasodilation, C. It penetrates the cornea and gets conveed to epinephrine, D. It increases intraocular pressure
C: It penetrates the cornea and gets conveed to epinephrine
Answer: C: It penetrates the cornea and gets conveed to epinephrine 
Explanation: Dipivefrine penetrates the cornea and is then hydrolysed to epinephrine by esterase enzymes. It increases outflow of the aqueous humour and also reduces its formation (mediated by its action on a1 and a2 receptors), thus reducing pressure inside the eye. Ref Davidson 23rd edition pg 457