This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Decreased glycolytic activity impairs oxygen transport by hemoglobin due to 
Select and explain. 
A. Reduced energy production, B. Decreased production of 2,3 - bisphosphoglycerate, C. Reduced synthesis of hemoglobin, D. Low levels of oxygen
B: Decreased production of 2,3 - bisphosphoglycerate
Answer: B: Decreased production of 2,3 - bisphosphoglycerate 
Explanation: Decreased production of 2,3-bisphosphoglycerate 

2, 3 DPG is produced by an alternative pathway in glycolysis.
If the glycolytic activity is decreased, the levels of 2,3 - DPG in RBCs will decrease.
Decreased level of 2,3 - DPG causes:-


Shifts the oxygen-hemoglobin curve to the left
Increases the oxygen affinity of hemoglobin.