This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endocrinology, Subject name: Pathology
Proopiomelanocoin is released from 
Select and explain. 
A. Hypothalamus, B. Liver, C. Adrenal, D. Lung
A: Hypothalamus
Answer: A: Hypothalamus 
Explanation: Proopiomelanocoin (POMC) is the pituitary precursor of circulating melanocyte stimulating hormone (a-MSH), adrenocoicotropin hormone (ACTH), and b-endorphin released from hypothalamus.