This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Spleen, Subject name: Surgery
Which of the following is a contraindication to nonoperative management of splenic injury? 
Select and explain. 
A. Prior hematologic disorder, B. HIV-positive patient, C. Hemodynamic instability, D. Multiple other solid-organ injuries
C: Hemodynamic instability
Answer: C: Hemodynamic instability 
Explanation: Hemodynamic instability is the most pressing indication for operative treatment in a patient with splenic injury. In all other situations listed a trial of nonoperative management may be continued.