This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Chronic and Cystic Diseases, Subject name: Pathology
Adult PCKD is? 
Select and explain. 
A. Autosomal dominant, B. Autosomal recessive, C. X-linked recessive, D. Mitochondrial inheritance
A: Autosomal dominant
Answer: A: Autosomal dominant 
Explanation: Ans is 'a' i.e. Autosomal dominant o ADPKD is an autosomal dominant disorder characterized by multiple expanding cysts of both kidneys that ultimately destroy renal parenchyma and cause renal failure in middle life (40-60 years of age)o Most commonly (85%) mutation involves PKD 1 gene on chromosome 16 encoding for polycystin 1 followed by PKD2 gene on chromosome 4 encoding for polycystin 2.