This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Endometriosis & H, Subject name: Gynaecology & Obstetrics
The lesion listed below that would most likely pursue a benign course is :- 
Select and explain. 
A. Vaginal adenosis, B. Adenomyosis, C. Extramammary Paget's disease, D. Endometrial hyperplasia
B: Adenomyosis
Answer: B: Adenomyosis 
Explanation: Adenomyosis is a benign condition characterised by the presence of benign endometrial glands and stroma within the myometrium, Common cause of diffuse uterine enlargement and menstrual irregularities. Vaginal adenosis is a DES-related precursor lesion for clear cell adenocarcinoma. Extrammary paget's disease is an intraepithelial adenocarcinoma. Endometrial hyperplasia is a precursor lesion of endometrial carcinoma.