This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Biochemistry
Ammonia is detoxified in brain to : 
Select and explain. 
A. Urea, B. Glutamine, C. GABA, D. Uric acid
B: Glutamine
Answer: B: Glutamine 
Explanation: Glutamine is the sole form of transpo of ammonia in brain.Glutamine is an amide of glutamic acid which is formed from alpha - ketoglutarate. (Product of TCA cycle).In metabolic alkalosis, there is decreased ammonia excretion in urine.