This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: Radiology Q Bank, Subject name: Radiology
A 50 years old woman present with complaint of rapidly progressive cognitive decline for past 3 months. Her MRI is given below. Diagnosis is- 
Select and explain. 
A. Diffuse hypoxic injury, B. CJD, C. MS, D. Aery of percheron infarct
B: CJD
Answer: B: CJD 
Explanation: CJD: Coical/gyral hyperintensity which shows restriction on DWI. Variant CJD: - Hockey stick sign/pulvinar sign - hyperintensity involving medial thalamic nuclei Diffuse hypoxic injury - don't present as progressive cognitive decline. History of hypoxic event is present. Aery of percheron infarct causes bilateral paramedian thalamic involvement is usually characterised by a triad of altered mental status, veical gaze palsy, and memory impairment.