This is a real-world medical entrance exam question, please give the true answer based on the question and selection. Topic name: None, Subject name: Medicine
Barret's esophagus is diagnosed by: 
Select and explain. 
A. Squamous metaplasia, B. Intestinal metaplasia, C. Squamous dysplasia, D. Intestinal dysplasia
B: Intestinal metaplasia
Answer: B: Intestinal metaplasia 
Explanation: Answer is B (Intestinal Metaplasia) Barret's esophagus is a metaplasia of the esophageal mucosa caused by replacement of squamous epithelium with columnar epithelium. Specialized intestinal epitheliutn (intestinal metaplasia) is the most common and most impoant type of columnar epithelium seen in Barret's esophagus.