R. Gupta
J. Eisen
N. Kyrpides
H. Klenk
C. Woese
Molecular signatures and phylogenomic analysis of the genus Burkholderia: proposal for division of this genus into the emended genus Burkholderia containing pathogenic organisms and a new genus…
A. Sawana, M. Adeolu, R. Gupta
Front. Genet.
The genus Burkholderia contains large number of diverse species which include many clinically important organisms, phytopathogens, as well as environmental species. However, currently, there is a… Expand
Protein Phylogenies and Signature Sequences: A Reappraisal of Evolutionary Relationships among Archaebacteria, Eubacteria, and Eukaryotes
SUMMARY The presence of shared conserved insertion or deletions (indels) in protein sequences is a special type of signature sequence that shows considerable promise for phylogenetic inference. An… Expand
Phylogenetic analysis of the 90 kD heat shock family of protein sequences and an examination of the relationship among animals, plants, and fungi species.
The heat shock protein (Hsp) sequences, because of their ubiquity and high degree of conservation, provide useful models for phylogenetic analysis. In this paper I have carried out a global alignment… Expand
Phylogenomics and Comparative Genomic Studies Robustly Support Division of the Genus Mycobacterium into an Emended Genus Mycobacterium and Four Novel Genera
R. Gupta, Brian Lo, Jeen Son
Front. Microbiol.
The genus Mycobacterium contains 188 species including several major human pathogens as well as numerous other environmental species. We report here comprehensive phylogenomics and comparative… Expand
The phylogeny of proteobacteria: relationships to other eubacterial phyla and eukaryotes.
FEMS microbiology reviews
The evolutionary relationships of proteobacteria, which comprise the largest and phenotypically most diverse division among prokaryotes, are examined based on the analyses of available molecular… Expand
Diversification of T Cell Responses to Carboxy-terminal Determinants within the 65-kD Heat-shock Protein Is Involved in Regulation of Autoimmune Arthritis
K. D. Moudgil, T. Chang, +4 authors E. Sercarz
The Journal of experimental medicine
The T cell response to the 65-kD mycobacterial heat-shock protein (Bhsp65) has been implicated in the pathogenesis of autoimmune arthritis. Adjuvant arthritis (AA) induced in the Lewis rat (RT-1l) by… Expand
Phylogenetic Framework and Molecular Signatures for the Main Clades of the Phylum Actinobacteria
Beile Gao, R. Gupta
Microbiology and Molecular Reviews
SUMMARY The phylum Actinobacteria harbors many important human pathogens and also provides one of the richest sources of natural products, including numerous antibiotics and other compounds of… Expand
Phylogenomics and signature proteins for the alpha Proteobacteria and its main groups
R. Gupta, A. Mok
BackgroundAlpha proteobacteria are one of the largest and most extensively studied groups within bacteria. However, for these bacteria as a whole and for all of its major subgroups (viz. Rhizobiales,… Expand
Signature proteins that are distinctive characteristics of Actinobacteria and their subgroups
Beile Gao, Ragi Paramanathan, R. Gupta
Antonie van Leeuwenhoek
The Actinobacteria constitute one of the main phyla of Bacteria. Presently, no morphological and very few molecular characteristics are known which can distinguish species of this highly diverse… Expand
Signature sequences in diverse proteins provide evidence for the late divergence of the Order Aquificales.
E. Griffiths, R. Gupta
International microbiology : the official journal…
The Aquificales species are presently believed to be the earliest branching lineage within Bacteria. However, the branching order of this group in different phylogenetic trees is highly variable and… Expand