Urea, polymer with ethanedial
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4,5-dihydroxyimidazolidin-2-one: The estimated vapour pressure at 25 ºC is 0.000433 Pa (EPI-Suite, MPBPWIN v1.43) 2-(dihydroxymethyl)-1,3-dioxolane-4,5-diol: The estimated vapour pressure at 25 ºC is 0.00016 Pa (EPI-Suite, MPBPWIN v1.43) 2-[4,5-dihydroxy-3-(1-hydroxy-2-oxoethyl)-2-oxoimidazolidin-1-yl]-2-hydroxyacetaldehyde: The estimated vapour pressure at 25 ºC is 1.13E-9 Pa (EPI-Suite, MPBPWIN v1.43)
OECD Guideline 104 (Vapour Pressure Curve)
EU Method A.4 (Vapour Pressure)
Vapour pressure:
21.1 hPa
The vapour pressure at 20 ºC and 25 °C was calculated on the basis of equation log (P) = f (1/t) = a-b/(t+273.15) where P – vapour pressure [hPa], t – temperature [°C].
The vapour pressure was determined to be 21.10 hPa. at 20ºC and 28.82 hPa. at 25ºC.
Determination of vapour pressure of the test substance was performed according to OECD 104 Guideline and EU A.4 Method, using the static method. Vapour pressure of test substance was calculated at 20 ºC and 25 ºC and was determined to be 21.10 hPa and 28.82 hPa respectively.
(Q)SAR
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Internationally accepted method, EPI-Suite, EPA (USA)
See attached the QMRF and QPRF for the QSAR model.
other: REACH Guidance on QSARs R.6
Lyman, W.J.1985. In: Environmental Exposure From Chemicals. Volume I., Neely,W.B. and Blau,G.E. (eds), Boca Raton, FL: CRC Press, Inc., Chapter 2.
Lyman, W.J., Reehl, W.F. and Rosenblatt, D.H. 1990. Handbook of Chemical Property Estimation Methods. Washington, DC: American Chemical Society, Chapter 14.
SMILES: OC(C1OC(O)C(O)O1)N2C(=O)N(C(O)C2O)C(O)C(O)N3C(=O)N(C(O)C3O)C(O)C=O
0 Pa
other: QSAR predicted value
MPBPVP predicted that the substance has a VP of 1.99E-024 Pa.
The estimated vapour pressure at 25 ºC is 1.99E-024 Pa (EPI-Suite, MPBPVP v1.43)
SMILES: OC1N(C(=O)N(C1O)C(O)C=O)C(O)C=O
SMILES: OC1NC(=O)NC1O
MPBPVP predicted that the substance has a VP of 0.000433 Pa.
The estimated vapour pressure at 25 ºC is 0.000433 Pa (EPI-Suite, MPBPVP v1.43)
SMILES: OC(C1OC(O)C(O)O1)N2C(=O)N(C(O)C2O)C(O)C=O
SMILES: OC1N(C(=O)N(C1O)C(O)C(O)NC(=O)NC(O)CO)C(O)C=O
Weight of evidence: Test method OECD 104. GLP study. The vapour pressure of the aqueous solution of the test item was determined to be 21.10 hPa at 20 ºC and 28.92 hPa at 25 ºC. Since the vapour pressure was measured for the aqueous solution, this result is overestimated.
Weight of evidence: Vapour pressure has been calculated by EPI-Suite, EPA (USA), MPBPVP v1.43 for the main constituents. The estimated vapour pressure for the substance has been determined to be 0.000433 Pa at 25ºC (highest calculated value as the worst case scenario).
at the temperature of:
Weight of evidence: Determination of vapour pressure of the test substance was performed according to OECD 104 Guideline and EU A.4 Method, using the static method. The vapour pressure of test substance was calculated at 20 ºC and 25 ºC and was determined to be 21.10 hPa and 28.82 hPa respectively.
According to Handbook of Chemistry and Physics: 73rd Edition (1992 -93), the vapour pressure of water at 20 and 25 ºC is 2.33880 and 3.16900 kPa respectively, which are equivalent to 23.3880 and 31.6900 hPa. Taking into account that the determination of the vapour pressure was performed with the test substance in aqueous solution, it could be concluded that the vapour pressure measured is related to the water content.
Weight of evidence: Vapour pressure of the main constituents has been calculated by EPI-Suite, EPA (USA), MPBPVP v1.43:
2-[3-(2{3-[4,5-dihydroxy-1,3-dioxolan-2-yl)(hydroxy)methyl]-4,5-dihydroxy-2-oxoimidazolidin-1-yl}-1,2-dihydroxyethyl)-4,5-dihydroxy-2-oxoimidazolidin-1-yl]-2-hydroxyacetaldehyde: The estimated vapour pressure at 25 ºC is 1.99E-024 Pa (EPI-Suite, MPBPVP v1.43).
2-[4,5-dihydroxy-3-(1-hydroxy-2-oxoethyl)-2-oxoimidazolidin-1-yl]-2-hydroxyacetaldehyde: The estimated vapour pressure at 25 ºC is 1.13E-009 Pa (EPI-Suite, MPBPVP v1.43).
4,5-dihydroxyimidazolidin-2-one: The estimated vapour pressure at 25 ºC is 0.000433 Pa (EPI-Suite, MPBPVP v1.43).
(2S)-2-[(4S,5S)-3-[(S)-[(4R,5R)-4,5-dihydroxy-1,3-dioxolan-2-yl](hydroxy)methyl]-4,5-dihydroxy-2-oxoimidazolidin-1-yl]-2-hydroxyacetaldehyde: The estimated vapour pressure at 25 ºC is 1.53E-013 Pa (EPI-Suite, MPBPVP v1.43).
1-{2-[4,5-dihydroxy-3-(1-hydroxy-2-oxoehtyl)-2-oxoimidazolidin-1-yl]-1,2-dihydroxyethyl}-3-(1,2-dihydroxyethyl)urea: The estimated vapour pressure at 25 ºC is 6.04E-018 Pa (EPI-Suite, MPBPVP v1.43).