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Vanderbilt Institute for Medicine and Public Health
VUMC, NIH launch clinical trial to test novel therapies to protect host tissue against COVID-19
https://news.vumc.org/2021/07/26/vumc-nih-launch-clinical-trial-to-test-novel-therapies-to-protect-host-tissue-against-covid-19/
Vanderbilt University Medical Center researchers, supported by the National Institutes of Health (NIH), are leading a nationwide clinical trial to explore the safety and effectiveness of a group of novel drugs designed to protect patients hospitalized with COVID-19 at high risk of poor outcomes. The new trial has enrolled its first patient.
COVID-19 Clinical Trials, Collins, Sean, Self, Wesley
VUMC to lead national study to treat severe COVID complications
https://news.vumc.org/2021/05/06/vumc-to-lead-national-study-to-treat-severe-covid-complications/
The Vanderbilt Institute for Clinical and Translational Research (VICTR) has been awarded a major federal grant to lead a national trial of treatments targeting the Renin Angiotensin Aldosterone System (RAAS) in patients hospitalized with COVID-19.
Collins, Sean, COVID-19 Clinical Trials, VICTR
Study aims to shield health workers from COVID-19 infection
https://news.vumc.org/2020/04/02/study-aims-to-shield-health-workers-from-covid-19-infection/
Vanderbilt University Medical Center is playing a key role in a national effort to establish a registry of U.S. health care workers and test whether the anti-malarial drug hydroxychloroquine (HCQ) will protect them, their patients and their families from COVID-19.
Rothman, Russell, Collins, Sean, Emergency Medicine, COVID-19, COVID-19 Studies/Grant Announcements, COVID-19 Clinical Trials
COVID19 Clinical Trials
COVID19 and Epidemiology/Health Services Research
COVID19 and Cognitive Function
COVID-19 and Health Equity
COVID-19 and Health Policy
STAR Clinical Research Network and PCORnet COVID-19 Common Data Model
The Stakeholders, Technology, and Research (STAR) CRN, led by Dr. Russell Rothman as the STAR CRN Lead PI, is launching a coordinated COVID-19 Common Data Model (CDM) at participating STAR CRN sites, in conjunction with the CDC and other PCORnet sites nationally. Funded by PCORI and the People Centered Research Foundation and designed to provide support for patient-centered outcomes research (PCORnet), the STAR CRN includes (1) Vanderbilt University Medical Center (2) the Vanderbilt Healthcare Affiliated Network (3) Meharry Medical College, (4) UNC Health Care System, (5) Duke Health Care System, (6) Health Sciences of South Carolina, (7) Wake Forest Health Care, and (8) Mayo Clinic. These systems comprise scores of academic and community hospitals, hundreds of practices and over 12 million patients nationally. In partnership with 8 additional Clinical Research Networks (CRNs), PCORnet engages with over 60 health systems and reaches over 90 million patients throughout the U.S. The purpose of the COVID-19 CDM is to characterize a cohort of COVID-19 patients nationally and provide detailed information on the demographics and pre-existing conditions for members of the CDC COVID-19 Task Force. The COVID-19 CDM will include patients testing positive for COVID-19 or with a coronavirus-related ICD 10 code. Queries will be issued weekly by the PCORnet Coordinating Center (DCRI) to ensure updated and ongoing reports to the CDC COVID-19 Task Force.
For more information, contact Megan Cook, MHA, Director of Operations/Sr. Project Manager, STAR CRN.
Advisory Memos on the COVID-19 Response
The Department of Health Policy in March 2020 convened a group of experts to offer guidance and curated reviews of current research and data related to the COVID-19 pandemic. These documents are intended for use by public health professionals and officials, and may be shared with attribution.
Epidemiology Center
Wei Zheng, M.D., Ph.D.
COVID-19 Weekly Summaries
Each week, the Vanderbilt Epidemiology Center faculty summarizes the most clinically relevant research about SARS-CoV-2 and COVID-19 as a service to the Vanderbilt University Medical Center.