Meningococcal Polysaccharide Vaccine, Group A; Neisseria meningitidis Group A vaccine; Menomune-A -- Product Record
Meningococcal Vaccine, A
Sanofi Pasteur S.A. -- Parent
Sanofi Pasteur Inc. -- Manuf. ; R&D ; Tech.
U.S. Department of Defense (DOD) -- Parent
Walter Reed Army Institute of Research (WRAIR), U.S. Army -- R&D ; Tech.
Sanofi S.A. -- Parent
Aventis Pasteur Inc. -- Former
Aventis Pasteur S.A -- Former
498 Meningococcal Vaccine, A
Meningococcal Polysaccharide Vaccine, Group A – Menomune-A; Neisseria meningitidis group A vaccine
Status: approved as component of multivalent vaccine
Sanofi Pasteur Inc. – Manuf.; R&D; Tech.
Sanofi Pasteur S.A. – Parent
Walter Reed Army Institute of Research (WRAIR), U.S. Army – R&D; Tech.
Cross ref: See the entries for Meningococcal Vaccines (#497) and Meningococcal Polysaccharide Vaccine, Groups A, C, Y, W135 Combined (#502).
Description: This product is used by Sanofi Pasteur Inc. for manufacture (as a component) of a combination vaccine – Meningococcal Polysaccharide Vaccine, Groups A, C, Y, W135 Combined (#502).
Nomenclature: Meningococcal Vaccine, A [BIO]; Meno-mune-A [TR]; Meningococcal Polysaccharide Vaccine, Group A [FDA]; Meningococcal Polysaccharide Vaccine Group A [USAN]; Meningococcal Polysaccharide Vaccine Group A USP [USP]; Neisseria meningitidis Group A vaccine [SY]
Companies.: The vaccine is manufactured by Sanofi Pasteur Inc. (Swiftwater, PA), CBER est. no. 1277.
FDA class: Biologic PLA
CBER class: Bacterial Antigens and Vaccines
Approvals: Date = 19751019; first approval, PLA (75-737), granted to Merrell-National Labs., Richardson-Merrell Inc.
Date = 19780103; approval revoked and granted (reissued) to new owner, Connaught Labs., Inc. (CLI)
Date = 19991209; approval revoked from CLI and granted (reissued) to new owner, Aventis Pasteur Inc.
Indications: for prevention of disease due to Neisseria meningitidis group A infection [unofficial]
Status: This product is approved, but is not marketed. It is used by Sanofi Pasteur Inc. for manufacture (as a component) of combination vaccines – Menomune-A/C/Y/W-135 (#502) and Menomune–A/C (#499). It is not approved or used as a monovalent vaccine in the European Union or other markets.
Meningococcal Vaccine, A [BIO]
Menomune-A [TR]
Meningococcal Polysaccharide Vaccine, Group A [FDA]
Meningococcal Polysaccharide Vaccine Group A [USAN]
Meningococcal Polysaccharide Vaccine Group A USP [USP]
MPSV4 [SY]
Neisseria meningitidis Group A vaccine [SY]
intermediate/precursor products
vaccines, bacterial
vaccines, subunit
bacterial culture <!-- bacterialculture -->
Mueller Hinton agar
Neisseria meningitidis group A-1
Watson Scherp media
Bacillus anthracis prophylaxis
cetyltrimethylammonium bromide (CTAB)
N-acetyl neuraminic acid
N-acetyl-O-acetyl mannosamine phosphate
Neisseria meningitidis capsular polysaccharides
Source/Host/Expression System: Bacterial cell culture micbac
approval dates uncertain (FDA reports erroneous, conflicting, or simply has lost the original approval dates) (FDAapproved)
North American coral snake
UM999 Not Available/Not Marketed in US
EM999 Not Available/Not Marketed in EU