Endoscopic treatment of bleeding ulcers: Has everything been said and done?
X. Calvet, M. Vergara, E. Brullet
Endoscopic treatment reduces bleeding recurrence, the need for surgery and mortality in patients with bleeding ulcers. However endoscopic treatment fails in 10-15% of patients, leading to high morbidity and mortality. The therapeutic measures with demonstrated effectiveness in reducing the risk of hemorrhagic recurrence and its complications are combined endoscopie treatment (adrenaline plus a second hemostatic intervention) and proton pump inhibitors. Also useful, although there is less evidence, are immediate resuscitation and «second look» endoscopy. Some studies suggest that activated recombinant factor VII infusion or supra-selective arterial embolization can be useful in severe hemorrhage. Further studies are required to determine optimal treatment according to the characteristics of each patient.
https://doi.org/10.1157/13076353
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Ulcer Medicine & Life Sciences
Hemorrhage Medicine & Life Sciences
Factor VIIa Medicine & Life Sciences
Hemostatics Medicine & Life Sciences
Resuscitation Medicine & Life Sciences
Calvet, X., Vergara, M., & Brullet, E. (2005). Endoscopic treatment of bleeding ulcers: Has everything been said and done? Gastroenterologia y Hepatologia, 28, 347-353. [76.1441]. https://doi.org/10.1157/13076353
Calvet, X. ; Vergara, M. ; Brullet, E. / Endoscopic treatment of bleeding ulcers: Has everything been said and done?. In: Gastroenterologia y Hepatologia. 2005 ; Vol. 28. pp. 347-353.
@article{7da4f59601a94272b13b2a40473e1cd3,
title = "Endoscopic treatment of bleeding ulcers: Has everything been said and done?",
abstract = "Endoscopic treatment reduces bleeding recurrence, the need for surgery and mortality in patients with bleeding ulcers. However endoscopic treatment fails in 10-15% of patients, leading to high morbidity and mortality. The therapeutic measures with demonstrated effectiveness in reducing the risk of hemorrhagic recurrence and its complications are combined endoscopie treatment (adrenaline plus a second hemostatic intervention) and proton pump inhibitors. Also useful, although there is less evidence, are immediate resuscitation and «second look» endoscopy. Some studies suggest that activated recombinant factor VII infusion or supra-selective arterial embolization can be useful in severe hemorrhage. Further studies are required to determine optimal treatment according to the characteristics of each patient.",
author = "X. Calvet and M. Vergara and E. Brullet",
doi = "https://doi.org/10.1157/13076353",
journal = "Gastroenterologia y Hepatologia",
publisher = "Ediciones Doyma, S.L.",
Calvet, X, Vergara, M & Brullet, E 2005, 'Endoscopic treatment of bleeding ulcers: Has everything been said and done?', Gastroenterologia y Hepatologia, vol. 28, 76.1441, pp. 347-353. https://doi.org/10.1157/13076353
Endoscopic treatment of bleeding ulcers: Has everything been said and done? / Calvet, X.; Vergara, M.; Brullet, E.
In: Gastroenterologia y Hepatologia, Vol. 28, 76.1441, 01.01.2005, p. 347-353.
T1 - Endoscopic treatment of bleeding ulcers: Has everything been said and done?
AU - Calvet, X.
AU - Vergara, M.
AU - Brullet, E.
N2 - Endoscopic treatment reduces bleeding recurrence, the need for surgery and mortality in patients with bleeding ulcers. However endoscopic treatment fails in 10-15% of patients, leading to high morbidity and mortality. The therapeutic measures with demonstrated effectiveness in reducing the risk of hemorrhagic recurrence and its complications are combined endoscopie treatment (adrenaline plus a second hemostatic intervention) and proton pump inhibitors. Also useful, although there is less evidence, are immediate resuscitation and «second look» endoscopy. Some studies suggest that activated recombinant factor VII infusion or supra-selective arterial embolization can be useful in severe hemorrhage. Further studies are required to determine optimal treatment according to the characteristics of each patient.
AB - Endoscopic treatment reduces bleeding recurrence, the need for surgery and mortality in patients with bleeding ulcers. However endoscopic treatment fails in 10-15% of patients, leading to high morbidity and mortality. The therapeutic measures with demonstrated effectiveness in reducing the risk of hemorrhagic recurrence and its complications are combined endoscopie treatment (adrenaline plus a second hemostatic intervention) and proton pump inhibitors. Also useful, although there is less evidence, are immediate resuscitation and «second look» endoscopy. Some studies suggest that activated recombinant factor VII infusion or supra-selective arterial embolization can be useful in severe hemorrhage. Further studies are required to determine optimal treatment according to the characteristics of each patient.
U2 - https://doi.org/10.1157/13076353
DO - https://doi.org/10.1157/13076353
JO - Gastroenterologia y Hepatologia
JF - Gastroenterologia y Hepatologia
M1 - 76.1441
Calvet X, Vergara M, Brullet E. Endoscopic treatment of bleeding ulcers: Has everything been said and done? Gastroenterologia y Hepatologia. 2005 Jan 1;28:347-353. 76.1441. https://doi.org/10.1157/13076353