James L Hougland
Syracuse University, Department of Chemistry
Syracuse University, The BioInspired Institute
Grants (14)
Press and Media (4)
Dive into the research topics where James L Hougland is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
Ghrelin Medicine & Life Sciences
Acyltransferases Chemical Compounds
Prenylation Medicine & Life Sciences
Farnesyltranstransferase Medicine & Life Sciences
p21(ras) farnesyl-protein transferase Medicine & Life Sciences
Acylation Chemical Compounds
geranylgeranyltransferase type-I Chemical Compounds
10 Finished
REU Site: Undergraduate Research in Chemistry at Syracuse University
Sponsler, M. & Hougland, J. L.
Determining the Scope of Prenylatable Protein Sequences
Hougland, J. L.
National Institute of General Medical Sciences/NIH/DHHS, University of Georgia
Defining the Molecular Architecture for Transmembrane Acylation by a Membrane Bound O-Acyltransferase
Hougland, J. L., Nangia, S. & Chisholm, J. D.
National Institutes of Health/DHHS
Hougland, J. L. & Chisholm, J. D.
Minority Undergraduate Internship Award
American Diabetes Association, Inc.
View all 14 grants
An overview of ghrelin O-acyltransferase inhibitors: a literature and patent review for 2010-2019
Moose, J. E., Leets, K. A., Mate, N. A., Chisholm, J. D. & Hougland, J. L., Aug 2 2020, In: Expert opinion on therapeutic patents. 30, 8, p. 581-593 13 p.
Peptidomimetics
Ghrelin Receptor
Protein Farnesyltransferase Catalyzes Unanticipated Farnesylation and Geranylgeranylation of Shortened Target Sequences
Ashok, S., Hildebrandt, E. R., Ruiz, C. S., Hardgrove, D. S., Coreno, D. W., Schmidt, W. K. & Hougland, J. L., Mar 24 2020, In: Biochemistry. 59, 11, p. 1149-1162 14 p.
p21(ras) farnesyl-protein transferase
Farnesyltranstransferase
Prenylation
geranylgeranyltransferase type-I
Biochemical assays for ghrelin acylation and inhibition of ghrelin O-acyltransferase
Sieburg, M. A., Cleverdon, E. R. & Hougland, J. L., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 227-241 15 p. (Methods in Molecular Biology; vol. 2009).
Ghrelin octanoylation by ghrelin O-acyltransferase: Unique protein biochemistry underlying metabolic signaling
Hougland, J. L., Jan 1 2019, In: Biochemical Society Transactions. 47, 1, p. 169-178 10 p.
protein acyltransferase
Ghrelin Signaling: GOAT and GHS-R1a Take a LEAP in Complexity
Abizaid, A. & Hougland, J. L., Jan 1 2019, (Accepted/In press) In: Trends in Endocrinology and Metabolism.
Weight loss news: This popular oil could be key to combating hunger
BIOCHEMISTS LINK SYNTHETIC COMPOUND TO HUNGER-HORMONE PRODUCTION
James L Hougland & John D Chisholm
US Patent Issued to SYRACUSE UNIVERSITY on May 17 for "Inhibitors targeting human ghrelin O-acyltransferase" (New York Inventor)
Who's in the news? James Hougland