Schizophrenia and genetics: new insights.
Anne S. Bassett, Eva W. Chow, Rosanna Weksberg, Linda Brzustowicz
There is consistent evidence that the principal etiology of schizophrenia involves predisposing genetic factors. Recent years have seen several new insights in the genetics of schizophrenia. Several chromosomal regions show significant evidence that they contain schizophrenia susceptibility genes. A clinically relevant genetic subtype of schizophrenia (22q deletion syndrome) has been identified. There is new evidence that spontaneous mutations may play a role. There are new recommendations for genetic counseling. The progress to date suggests that understanding of a neurodevelopmental pathway from genetic susceptibility to schizophrenia will soon be fundamentally altered by molecular genetic advances in this complex disease.
https://doi.org/10.1007/s11920-996-0051-x
Genetic Predisposition to Disease
Bassett, A. S., Chow, E. W., Weksberg, R., & Brzustowicz, L. (2002). Schizophrenia and genetics: new insights. Current psychiatry reports, 4(4), 307-314. https://doi.org/10.1007/s11920-996-0051-x
Bassett, Anne S. ; Chow, Eva W. ; Weksberg, Rosanna ; Brzustowicz, Linda. / Schizophrenia and genetics : new insights. In: Current psychiatry reports. 2002 ; Vol. 4, No. 4. pp. 307-314.
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title = "Schizophrenia and genetics: new insights.",
abstract = "There is consistent evidence that the principal etiology of schizophrenia involves predisposing genetic factors. Recent years have seen several new insights in the genetics of schizophrenia. Several chromosomal regions show significant evidence that they contain schizophrenia susceptibility genes. A clinically relevant genetic subtype of schizophrenia (22q deletion syndrome) has been identified. There is new evidence that spontaneous mutations may play a role. There are new recommendations for genetic counseling. The progress to date suggests that understanding of a neurodevelopmental pathway from genetic susceptibility to schizophrenia will soon be fundamentally altered by molecular genetic advances in this complex disease.",
author = "Bassett, {Anne S.} and Chow, {Eva W.} and Rosanna Weksberg and Linda Brzustowicz",
doi = "10.1007/s11920-996-0051-x",
journal = "Current Psychiatry Reports",
publisher = "Current Science, Inc.",
Bassett, AS, Chow, EW, Weksberg, R & Brzustowicz, L 2002, 'Schizophrenia and genetics: new insights.', Current psychiatry reports, vol. 4, no. 4, pp. 307-314. https://doi.org/10.1007/s11920-996-0051-x
Schizophrenia and genetics : new insights. / Bassett, Anne S.; Chow, Eva W.; Weksberg, Rosanna; Brzustowicz, Linda.
In: Current psychiatry reports, Vol. 4, No. 4, 01.01.2002, p. 307-314.
T1 - Schizophrenia and genetics
T2 - new insights.
AU - Bassett, Anne S.
AU - Chow, Eva W.
AU - Weksberg, Rosanna
AU - Brzustowicz, Linda
N2 - There is consistent evidence that the principal etiology of schizophrenia involves predisposing genetic factors. Recent years have seen several new insights in the genetics of schizophrenia. Several chromosomal regions show significant evidence that they contain schizophrenia susceptibility genes. A clinically relevant genetic subtype of schizophrenia (22q deletion syndrome) has been identified. There is new evidence that spontaneous mutations may play a role. There are new recommendations for genetic counseling. The progress to date suggests that understanding of a neurodevelopmental pathway from genetic susceptibility to schizophrenia will soon be fundamentally altered by molecular genetic advances in this complex disease.
AB - There is consistent evidence that the principal etiology of schizophrenia involves predisposing genetic factors. Recent years have seen several new insights in the genetics of schizophrenia. Several chromosomal regions show significant evidence that they contain schizophrenia susceptibility genes. A clinically relevant genetic subtype of schizophrenia (22q deletion syndrome) has been identified. There is new evidence that spontaneous mutations may play a role. There are new recommendations for genetic counseling. The progress to date suggests that understanding of a neurodevelopmental pathway from genetic susceptibility to schizophrenia will soon be fundamentally altered by molecular genetic advances in this complex disease.
U2 - 10.1007/s11920-996-0051-x
DO - 10.1007/s11920-996-0051-x
JO - Current Psychiatry Reports
JF - Current Psychiatry Reports
Bassett AS, Chow EW, Weksberg R, Brzustowicz L. Schizophrenia and genetics: new insights. Current psychiatry reports. 2002 Jan 1;4(4):307-314. https://doi.org/10.1007/s11920-996-0051-x