Incidence, correlates, management, and clinical outcome of coronary perforation: Analysis of 16,298 procedures
Panayotis Fasseas, James L. Orford, Carmelo J. Panetta, Malcolm R. Bell, Ali E. Denktas, Ryan J. Lennon, David R. Holmes, Peter B. Berger
Background: Coronary perforation is a serious but uncommon complication of percutaneous coronary intervention (PCI) and is associated with significant morbidity and mortality. Methods: We performed an analysis of the Mayo Clinic PCI database. Clinical records, procedural reports, and angiographic studies were reviewed. Multiple logistic regression analysis was performed to identify clinical, procedural, anatomic, and angiographic correlates of coronary perforation. Results: A total of 16,298 PCI procedures were performed between January 1990 and December 2001. We identified 95 coronary perforations (0.58%; 95% CI, 0.47-0.71). The incidence of coronary perforation varied with time. Correlates of coronary perforation included the use of an atheroablative device and female sex. Twelve patients (12.6%) sustained an acute myocardial infarction, and cardiac tamponade developed in 11 patients (11.6%). Management strategies included reversal of heparin, pericardiocentesis, placement of a covered stent, and surgical repair. Seven patients died (7.4%). Conclusions: Coronary perforation during PCI is rare, but is associated with significant morbidity and mortality. The variable frequency of perforation may be explained by temporal variations in the use of atheroablative devices.
American heart journal
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Percutaneous Coronary Intervention Medicine & Life Sciences
Pericardiocentesis Medicine & Life Sciences
Cardiac Tamponade Medicine & Life Sciences
Equipment and Supplies Medicine & Life Sciences
Morbidity Medicine & Life Sciences
Heparin Medicine & Life Sciences
Fasseas, P., Orford, J. L., Panetta, C. J., Bell, M. R., Denktas, A. E., Lennon, R. J., Holmes, D. R., & Berger, P. B. (2004). Incidence, correlates, management, and clinical outcome of coronary perforation: Analysis of 16,298 procedures. American heart journal, 147(1), 140-145. https://doi.org/10.1016/S0002-8703(03)00505-2
Incidence, correlates, management, and clinical outcome of coronary perforation : Analysis of 16,298 procedures. / Fasseas, Panayotis; Orford, James L.; Panetta, Carmelo J.; Bell, Malcolm R.; Denktas, Ali E.; Lennon, Ryan J.; Holmes, David R.; Berger, Peter B.
In: American heart journal, Vol. 147, No. 1, 01.2004, p. 140-145.
Fasseas, P, Orford, JL, Panetta, CJ, Bell, MR, Denktas, AE, Lennon, RJ, Holmes, DR & Berger, PB 2004, 'Incidence, correlates, management, and clinical outcome of coronary perforation: Analysis of 16,298 procedures', American heart journal, vol. 147, no. 1, pp. 140-145. https://doi.org/10.1016/S0002-8703(03)00505-2
Fasseas P, Orford JL, Panetta CJ, Bell MR, Denktas AE, Lennon RJ et al. Incidence, correlates, management, and clinical outcome of coronary perforation: Analysis of 16,298 procedures. American heart journal. 2004 Jan;147(1):140-145. https://doi.org/10.1016/S0002-8703(03)00505-2
Fasseas, Panayotis ; Orford, James L. ; Panetta, Carmelo J. ; Bell, Malcolm R. ; Denktas, Ali E. ; Lennon, Ryan J. ; Holmes, David R. ; Berger, Peter B. / Incidence, correlates, management, and clinical outcome of coronary perforation : Analysis of 16,298 procedures. In: American heart journal. 2004 ; Vol. 147, No. 1. pp. 140-145.
@article{4ff9cf7a56d34acb9e0e5204112f41b2,
title = "Incidence, correlates, management, and clinical outcome of coronary perforation: Analysis of 16,298 procedures",
abstract = "Background: Coronary perforation is a serious but uncommon complication of percutaneous coronary intervention (PCI) and is associated with significant morbidity and mortality. Methods: We performed an analysis of the Mayo Clinic PCI database. Clinical records, procedural reports, and angiographic studies were reviewed. Multiple logistic regression analysis was performed to identify clinical, procedural, anatomic, and angiographic correlates of coronary perforation. Results: A total of 16,298 PCI procedures were performed between January 1990 and December 2001. We identified 95 coronary perforations (0.58%; 95% CI, 0.47-0.71). The incidence of coronary perforation varied with time. Correlates of coronary perforation included the use of an atheroablative device and female sex. Twelve patients (12.6%) sustained an acute myocardial infarction, and cardiac tamponade developed in 11 patients (11.6%). Management strategies included reversal of heparin, pericardiocentesis, placement of a covered stent, and surgical repair. Seven patients died (7.4%). Conclusions: Coronary perforation during PCI is rare, but is associated with significant morbidity and mortality. The variable frequency of perforation may be explained by temporal variations in the use of atheroablative devices.",
author = "Panayotis Fasseas and Orford, {James L.} and Panetta, {Carmelo J.} and Bell, {Malcolm R.} and Denktas, {Ali E.} and Lennon, {Ryan J.} and Holmes, {David R.} and Berger, {Peter B.}",
journal = "American Heart Journal",
publisher = "Mosby Inc.",
T1 - Incidence, correlates, management, and clinical outcome of coronary perforation
T2 - Analysis of 16,298 procedures
AU - Fasseas, Panayotis
AU - Orford, James L.
AU - Panetta, Carmelo J.
AU - Bell, Malcolm R.
AU - Denktas, Ali E.
AU - Lennon, Ryan J.
AU - Holmes, David R.
AU - Berger, Peter B.
N2 - Background: Coronary perforation is a serious but uncommon complication of percutaneous coronary intervention (PCI) and is associated with significant morbidity and mortality. Methods: We performed an analysis of the Mayo Clinic PCI database. Clinical records, procedural reports, and angiographic studies were reviewed. Multiple logistic regression analysis was performed to identify clinical, procedural, anatomic, and angiographic correlates of coronary perforation. Results: A total of 16,298 PCI procedures were performed between January 1990 and December 2001. We identified 95 coronary perforations (0.58%; 95% CI, 0.47-0.71). The incidence of coronary perforation varied with time. Correlates of coronary perforation included the use of an atheroablative device and female sex. Twelve patients (12.6%) sustained an acute myocardial infarction, and cardiac tamponade developed in 11 patients (11.6%). Management strategies included reversal of heparin, pericardiocentesis, placement of a covered stent, and surgical repair. Seven patients died (7.4%). Conclusions: Coronary perforation during PCI is rare, but is associated with significant morbidity and mortality. The variable frequency of perforation may be explained by temporal variations in the use of atheroablative devices.
AB - Background: Coronary perforation is a serious but uncommon complication of percutaneous coronary intervention (PCI) and is associated with significant morbidity and mortality. Methods: We performed an analysis of the Mayo Clinic PCI database. Clinical records, procedural reports, and angiographic studies were reviewed. Multiple logistic regression analysis was performed to identify clinical, procedural, anatomic, and angiographic correlates of coronary perforation. Results: A total of 16,298 PCI procedures were performed between January 1990 and December 2001. We identified 95 coronary perforations (0.58%; 95% CI, 0.47-0.71). The incidence of coronary perforation varied with time. Correlates of coronary perforation included the use of an atheroablative device and female sex. Twelve patients (12.6%) sustained an acute myocardial infarction, and cardiac tamponade developed in 11 patients (11.6%). Management strategies included reversal of heparin, pericardiocentesis, placement of a covered stent, and surgical repair. Seven patients died (7.4%). Conclusions: Coronary perforation during PCI is rare, but is associated with significant morbidity and mortality. The variable frequency of perforation may be explained by temporal variations in the use of atheroablative devices.
JO - American Heart Journal
JF - American Heart Journal