Space research on organs and tissues
Marc E. Tischler, Emily Morey-Holton
Studies in space on various physiological systems have and will continue to provide valuable information on how they adapt to reduced gravitational conditions, and how living in a one G (gravity) environment has guided their development. Muscle and bone are the most notable tissues which respond to unweighting caused by lack of gravity. The function of specific muscles and bones relates directly to mechanical loading, so that removal of "normal forces" in space, or bedridden patients, causes dramatic loss of tissue mass. The cardiovascular system is also markedly affected by reduced gravity. Adaptation includes decreased blood flow to the lower extremities thus decreasing the heart output requirement. Hence return to one G is associated with a period of reconditioning due to the deconditioning that occurs in space. Changes in the cardiovascular system are also related to responses of the kidney and certain endocrine (hormone-producing) organs. Changes in respiratory function may also occur, suggesting an effect on the lungs though this adaptation is poorly understood. The neurovestibular system, including the brain and organs of the inner car, must adapt to the disorientation caused by lack of gravity. Preliminary findings have been reported for liver. Additionally endocrine organs responsible for release of hormones, such as insulin, growth hormone, glucocorticoids, and thyroid hormone may respond to spaceflight.
AIAA Space Programs and Technologies Conference, 1992 - Huntsville, United States
AIAA Space Programs and Technologies Conference, 1992
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Space research Engineering & Materials Science 100%
hormones Physics & Astronomy 99%
space research Earth & Environmental Sciences 91%
Hormones Engineering & Materials Science 76%
hormone Earth & Environmental Sciences 73%
organs Physics & Astronomy 72%
cardiovascular system Physics & Astronomy 65%
Gravitation Engineering & Materials Science 61%
Tischler, M. E., & Morey-Holton, E. (1992). Space research on organs and tissues. Paper presented at AIAA Space Programs and Technologies Conference, 1992, Huntsville, United States.
Space research on organs and tissues. / Tischler, Marc E.; Morey-Holton, Emily.
1992. Paper presented at AIAA Space Programs and Technologies Conference, 1992, Huntsville, United States.
Tischler, ME & Morey-Holton, E 1992, 'Space research on organs and tissues', Paper presented at AIAA Space Programs and Technologies Conference, 1992, Huntsville, United States, 3/24/92 - 3/27/92.
Tischler ME, Morey-Holton E. Space research on organs and tissues. 1992. Paper presented at AIAA Space Programs and Technologies Conference, 1992, Huntsville, United States.
Tischler, Marc E. ; Morey-Holton, Emily. / Space research on organs and tissues. Paper presented at AIAA Space Programs and Technologies Conference, 1992, Huntsville, United States.
@conference{3b74a687aea14fb3aa74c7c63819b9a1,
title = "Space research on organs and tissues",
abstract = "Studies in space on various physiological systems have and will continue to provide valuable information on how they adapt to reduced gravitational conditions, and how living in a one G (gravity) environment has guided their development. Muscle and bone are the most notable tissues which respond to unweighting caused by lack of gravity. The function of specific muscles and bones relates directly to mechanical loading, so that removal of "normal forces" in space, or bedridden patients, causes dramatic loss of tissue mass. The cardiovascular system is also markedly affected by reduced gravity. Adaptation includes decreased blood flow to the lower extremities thus decreasing the heart output requirement. Hence return to one G is associated with a period of reconditioning due to the deconditioning that occurs in space. Changes in the cardiovascular system are also related to responses of the kidney and certain endocrine (hormone-producing) organs. Changes in respiratory function may also occur, suggesting an effect on the lungs though this adaptation is poorly understood. The neurovestibular system, including the brain and organs of the inner car, must adapt to the disorientation caused by lack of gravity. Preliminary findings have been reported for liver. Additionally endocrine organs responsible for release of hormones, such as insulin, growth hormone, glucocorticoids, and thyroid hormone may respond to spaceflight.",
author = "Tischler, {Marc E.} and Emily Morey-Holton",
note = "AIAA Space Programs and Technologies Conference, 1992 ; Conference date: 24-03-1992 Through 27-03-1992",
T1 - Space research on organs and tissues
AU - Tischler, Marc E.
AU - Morey-Holton, Emily
N2 - Studies in space on various physiological systems have and will continue to provide valuable information on how they adapt to reduced gravitational conditions, and how living in a one G (gravity) environment has guided their development. Muscle and bone are the most notable tissues which respond to unweighting caused by lack of gravity. The function of specific muscles and bones relates directly to mechanical loading, so that removal of "normal forces" in space, or bedridden patients, causes dramatic loss of tissue mass. The cardiovascular system is also markedly affected by reduced gravity. Adaptation includes decreased blood flow to the lower extremities thus decreasing the heart output requirement. Hence return to one G is associated with a period of reconditioning due to the deconditioning that occurs in space. Changes in the cardiovascular system are also related to responses of the kidney and certain endocrine (hormone-producing) organs. Changes in respiratory function may also occur, suggesting an effect on the lungs though this adaptation is poorly understood. The neurovestibular system, including the brain and organs of the inner car, must adapt to the disorientation caused by lack of gravity. Preliminary findings have been reported for liver. Additionally endocrine organs responsible for release of hormones, such as insulin, growth hormone, glucocorticoids, and thyroid hormone may respond to spaceflight.
AB - Studies in space on various physiological systems have and will continue to provide valuable information on how they adapt to reduced gravitational conditions, and how living in a one G (gravity) environment has guided their development. Muscle and bone are the most notable tissues which respond to unweighting caused by lack of gravity. The function of specific muscles and bones relates directly to mechanical loading, so that removal of "normal forces" in space, or bedridden patients, causes dramatic loss of tissue mass. The cardiovascular system is also markedly affected by reduced gravity. Adaptation includes decreased blood flow to the lower extremities thus decreasing the heart output requirement. Hence return to one G is associated with a period of reconditioning due to the deconditioning that occurs in space. Changes in the cardiovascular system are also related to responses of the kidney and certain endocrine (hormone-producing) organs. Changes in respiratory function may also occur, suggesting an effect on the lungs though this adaptation is poorly understood. The neurovestibular system, including the brain and organs of the inner car, must adapt to the disorientation caused by lack of gravity. Preliminary findings have been reported for liver. Additionally endocrine organs responsible for release of hormones, such as insulin, growth hormone, glucocorticoids, and thyroid hormone may respond to spaceflight.
T2 - AIAA Space Programs and Technologies Conference, 1992