Home / J. Cardiovasc. Dis. Res., 4(2), 2013 / Pulsatile versus non-pulsatile flow to reduce cognitive decline after coronary artery bypass surgery: A randomized prospective clinical trial
Pulsatile versus non-pulsatile flow to reduce cognitive decline after coronary artery bypass surgery: A randomized prospective clinical trial
Journal of Cardiovascular Disease Research,2013,4,2,127-129.
DOI:10.1016/j.jcdr.2013.05.005
Published:June 2013
Koray Aykut,
Gokhan Albayrak,
Mehmet Guzeloglu,
Eyup Hazan,
Muge Tufekci,
and Ipek Erdogan
Koray Aykut a,*, Gokhan Albayrak a, Mehmet Guzeloglu a, Eyup Hazan a, Muge Tufekci b, Ipek Erdogan b
a Department of Cardiovascular Surgery, Faculty of Medicine, Izmir University, Izmir 35000, Turkey
b Department of Psychology, Faculty of Medicine, Izmir University, Izmir 35000, Turkey
Background: In this prospective study, we aimed to compare the effect of pulsatile and non-pulsatile flow on the cognitive functions in patients undergoing coronary artery bypass surgery. Methods: Patients scheduled for their first coronary artery bypass surgery (n ¼ 148) were randomly assigned to the pulsatile flow group (Group A, n ¼ 75) or non-pulsatil group (Group B, n ¼ 73). Cognitive performance was assessed with (MoCA) montreal cognitive assessment test performed by psychologists before coronary artery bypass surgery and 1 month after the operation. Results: Mild cognitive impairment was seen in 12 (16%) patients and serious cognitive impairment was seen in 1 (1.33%) patient in the pulsatile flow group. In the other group, mild cognitive impairment was detected in 23 (31.50%) patients and serious cognitive decline was found in 3 (4.10%) patients. Mean MoCA scores were 25.86 2.62 in group A and 22.12 2.20 in group B. The difference between two groups was statistically significant (P ¼ 0.041). Conclusions: We suggest that pulsatile flow has beneficial effects to decrease cognitive dysfunction in patients undergoing on-pump coronary artery bypass surgery.
Keywords:Cognitive dysfunction, Coronary artery bypass surgery, On-pump
‹ Age and clinical outcomes in patients presenting with acute coronary syndromes
Prevalence of cardiovascular risk factors among rural population of elderly in Wardha district ›
Aykut K, Albayrak G, Guzeloglu M, Hazan E, Tufekci M, Erdogan I. Pulsatile versus non-pulsatile flow to reduce cognitive decline after coronary artery bypass surgery: A randomized prospective clinical trial. Journal of Cardiovascular Disease Research. 2013;4(2):127-129.
On-pump
Efficacy of Bilateral Continuous Paravertebral Block for Off Pump Coronary Artery Bypass Surgery