Memantine for pain control in fibromyalgia
The prevalence of fibromyalgia in our clinical practices is about 2%-3%. But it may feel much higher, because some of these patients use a lot of staff and office time. Vacillations in our certainty...
Aspirin, hydrochlorothiazide okay in gout
It's okay in most cases for gout patients to be on thiazide diuretics or low-dose aspirin, so long as hypouricemic therapy is adjusted as needed, according to rheumatologist and Cleveland Clinic...
Tissue-based treatment could improve psoriatic arthritis outcomes
Efforts underway to tailor psoriatic arthritis treatments to the various tissues involved in the pathogenesis of the disease could optimize therapeutic approaches, Dr. Iain McInnes said at the annual...
Fibromyalgia does not fit an analogy
The power of the central sensitization analogy – the idea that pain is best thought about as a stereo with the volume turned up – has led to the science of fibromyalgia becoming "lost in...
Methotrexate ups risk of liver abnormalities, but not serious hepatic events
Methotrexate use more than doubled the risk of liver enzyme abnormalities but was not tied to serious hepatic outcomes among patients with rheumatic diseases, according to a meta-analysis of 32...
Spondyloarthritides undergoing a renaissance, but challenges exist
Rheumatologists' understanding of the spectrum of spondyloarthritis is undergoing an evolution that has revealed an underrecognition of the disease, particularly in women, but regulatory recognition...
New ACR/EULAR gout classification criteria offer better sensitivity, specificity
The presence of monosodium urate monohydrate crystals in a symptomatic joint, bursa, or tophus is sufficient to diagnose gout, according to new gout classification criteria from the American College...
Knee OA patients see most benefit from small doses of fish oil
The anti-inflammatory properties of fish oil have been demonstrated, but for patients with knee osteoarthritis, high doses of fish oil were no more effective than was low-dose fish oil, according to...
Biomarker test couldn't predict RA transformation from undifferentiated arthritis
Baseline assessment of patients with undifferentiated arthritis at an early disease stage with the multibiomarker disease activity score did not discriminate patients who continued to have...
Infliximab biosimilar SB2 shows efficacy, safety similar to Remicade for RA
The investigational infliximab biosimilar drug SB2 provided efficacy and safety equivalent to the originator drug Remicade in patients with moderate to severe rheumatoid arthritis in a phase III...