The gastrointestinal transit profile of 14C-labelled poly(acrylic acids): an in vivo study
R.G. Riley, K.L. Green, John Smart, J. Tsibouklis, J.A. Davis, F. Hampson, P.W. Dettmar, W.R. Wilber
The gastrointestinal distribution profiles for three 14C-labelled poly(acrylic acid)s of different average molecular weights and degrees of cross-linking have been established using the rat model. Despite initial differences in transit times and retention characteristics, these structural features were found to be of little influence to the overall gastrointestinal transit of the materials under consideration. No evidence for the systemic absorption of any of the polymers could be identified.
14C-poly(acrylic acid)
Polymer retention
Mucoadhesion
10.1016/S0142-9612(00)00369-0Licence: Unspecified
http://www.sciencedirect.com/science/article/pii/S0142961200003690Licence: Unspecified
Fingerprint Dive into the research topics of 'The gastrointestinal transit profile of 14C-labelled poly(acrylic acids): an in vivo study'. Together they form a unique fingerprint.
acrylic acid Physics & Astronomy
transit time Physics & Astronomy
transit Physics & Astronomy
rats Physics & Astronomy
molecular weight Physics & Astronomy
polymers Physics & Astronomy
profiles Physics & Astronomy
Riley, R. G., Green, K. L., Smart, J., Tsibouklis, J., Davis, J. A., Hampson, F., Dettmar, P. W., & Wilber, W. R. (2001). The gastrointestinal transit profile of 14C-labelled poly(acrylic acids): an in vivo study. Biomaterials, 22(13), 1861-1867. https://doi.org/10.1016/S0142-9612(00)00369-0
Riley, R.G. ; Green, K.L. ; Smart, John ; Tsibouklis, J. ; Davis, J.A. ; Hampson, F. ; Dettmar, P.W. ; Wilber, W.R. / The gastrointestinal transit profile of 14C-labelled poly(acrylic acids): an in vivo study. In: Biomaterials. 2001 ; Vol. 22, No. 13. pp. 1861-1867.
@article{d857bd74f9a7486facd1796a4fc37064,
title = "The gastrointestinal transit profile of 14C-labelled poly(acrylic acids): an in vivo study",
abstract = "The gastrointestinal distribution profiles for three 14C-labelled poly(acrylic acid)s of different average molecular weights and degrees of cross-linking have been established using the rat model. Despite initial differences in transit times and retention characteristics, these structural features were found to be of little influence to the overall gastrointestinal transit of the materials under consideration. No evidence for the systemic absorption of any of the polymers could be identified.",
keywords = "14C-poly(acrylic acid), In vivo, Polymer retention, Mucoadhesion",
author = "R.G. Riley and K.L. Green and John Smart and J. Tsibouklis and J.A. Davis and F. Hampson and P.W. Dettmar and W.R. Wilber",
journal = "Biomaterials",
Riley, RG, Green, KL, Smart, J, Tsibouklis, J, Davis, JA, Hampson, F, Dettmar, PW & Wilber, WR 2001, 'The gastrointestinal transit profile of 14C-labelled poly(acrylic acids): an in vivo study', Biomaterials, vol. 22, no. 13, pp. 1861-1867. https://doi.org/10.1016/S0142-9612(00)00369-0
The gastrointestinal transit profile of 14C-labelled poly(acrylic acids): an in vivo study. / Riley, R.G.; Green, K.L.; Smart, John; Tsibouklis, J.; Davis, J.A.; Hampson, F.; Dettmar, P.W.; Wilber, W.R.
In: Biomaterials, Vol. 22, No. 13, 07.2001, p. 1861-1867.
T1 - The gastrointestinal transit profile of 14C-labelled poly(acrylic acids): an in vivo study
AU - Riley, R.G.
AU - Green, K.L.
AU - Smart, John
AU - Tsibouklis, J.
AU - Davis, J.A.
AU - Hampson, F.
AU - Dettmar, P.W.
AU - Wilber, W.R.
N2 - The gastrointestinal distribution profiles for three 14C-labelled poly(acrylic acid)s of different average molecular weights and degrees of cross-linking have been established using the rat model. Despite initial differences in transit times and retention characteristics, these structural features were found to be of little influence to the overall gastrointestinal transit of the materials under consideration. No evidence for the systemic absorption of any of the polymers could be identified.
AB - The gastrointestinal distribution profiles for three 14C-labelled poly(acrylic acid)s of different average molecular weights and degrees of cross-linking have been established using the rat model. Despite initial differences in transit times and retention characteristics, these structural features were found to be of little influence to the overall gastrointestinal transit of the materials under consideration. No evidence for the systemic absorption of any of the polymers could be identified.
KW - 14C-poly(acrylic acid)
KW - In vivo
KW - Polymer retention
KW - Mucoadhesion
JO - Biomaterials
JF - Biomaterials
Riley RG, Green KL, Smart J, Tsibouklis J, Davis JA, Hampson F et al. The gastrointestinal transit profile of 14C-labelled poly(acrylic acids): an in vivo study. Biomaterials. 2001 Jul;22(13):1861-1867. https://doi.org/10.1016/S0142-9612(00)00369-0