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1. Colasanto, Marlena. A Comparative Study of Repetitive Behaviours in Pediatric Obsessive-compulsive Disorder and Autism Spectrum Disorder.
Repetitive behaviours are a core feature and source of impairment in two neurodevelopmental disorders: obsessive-compulsive disorder (OCD) and autism spectrum disorder (ASD). However, few studies… (more)
Repetitive behaviours are a core feature and source of impairment in two neurodevelopmental disorders: obsessive-compulsive disorder (OCD) and autism spectrum disorder (ASD). However, few studies have systematically examined repetitive behaviours across these two disorders. As part of the Province of Ontario Neurodevelopmental Disorders network we compared repetitive behaviour subtypes in children and adolescents with OCD and ASD using several instruments. Findings revealed marked heterogeneity of repetitive behaviour subtypes in children and adolescents with OCD and ASD. Results suggest repetitive behaviour subtypes that are more common in OCD, ASD, and equally prevalent across disorders. Findings will help guide future pathophysiological studies by localizing dimensional traits of repetitive behaviours across disorders.
Advisors/Committee Members: Arnold, Paul D, Medical Science.
Subjects/Keywords: 0347
Colasanto, M. (2015). A Comparative Study of Repetitive Behaviours in Pediatric Obsessive-compulsive Disorder and Autism Spectrum Disorder . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/70271
Colasanto, Marlena. "A Comparative Study of Repetitive Behaviours in Pediatric Obsessive-compulsive Disorder and Autism Spectrum Disorder." 2015. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/70271.
Colasanto, Marlena. "A Comparative Study of Repetitive Behaviours in Pediatric Obsessive-compulsive Disorder and Autism Spectrum Disorder." 2015. Web. 17 Jan 2021.
Colasanto M. A Comparative Study of Repetitive Behaviours in Pediatric Obsessive-compulsive Disorder and Autism Spectrum Disorder. [Internet] [Masters thesis]. University of Toronto; 2015. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/70271.
Colasanto M. A Comparative Study of Repetitive Behaviours in Pediatric Obsessive-compulsive Disorder and Autism Spectrum Disorder. [Masters Thesis]. University of Toronto; 2015. Available from: http://hdl.handle.net/1807/70271
2. Sheldon, C. Tess. Meds on the Menu: The Covert Administration of Psychotropic Medication to Adult Inpatients Determined to be Decisionally-Incapable in Ontario's Psychiatric Settings.
Degree: PhD, 2015, University of Toronto
Drawing on the fields of human rights and public health, this research explores the covert administration of medication: the concealment of medication in food or… (more)
Drawing on the fields of human rights and public health, this research explores the covert administration of medication: the concealment of medication in food or drink so that it will be consumed undetected. Adopting a rights-based approach, it explores multiple understandings of the impact of the practice on inpatients' rights-experiences. Relying on critical approaches, it also explores the practice's underlying socio-political-legal structures. The common themes of policies, protocols or guidelines that govern its practice in Ontario are identified. Focus groups and individual interviews were held with three groups of stakeholders (nurses, legal experts and psychiatrists), relying on fictional clinical scenarios. Few policies, protocols or guidelines govern the practice in Ontario's psychiatric settings. The practice impairs access to knowledge by patients and substitute decision-makers. It also precludes healthcare practitioners' access to information about side effects and underlying reasons for medication refusal. It may interfere with therapeutic relationships and patients' meaningful recovery as they transfer from hospital without knowledge of the fact of the covert medication. It may be characterized as autonomy restoring since patients may become capable of making treatment decisions after having received the medication surreptitiously. Covert medication reflects an inflexible approach to capacity determination; it is distinguishable from approaches that imagine capacity as able to be fostered with support. It is primarily concerned with the management of "risky" inpatients in the short-term. The practice relies on a faith that medication will be effective, deferring to medical decision-making. While covert medication is understood to have "something to do" with rights, there is confusion about how those rights play out on the ground. Institutional silences underlie and reinforce the practice. This research will support the development of effective, safe and appropriate approaches to treatment non-adherence that maximize patient dignity. Most pressing, this research concludes that the covert administration of medication warrants an overt discussion.
Advisors/Committee Members: Ferris, Lorraine, Dalla Lana School of Public Health.
Sheldon, C. T. (2015). Meds on the Menu: The Covert Administration of Psychotropic Medication to Adult Inpatients Determined to be Decisionally-Incapable in Ontario's Psychiatric Settings . (Doctoral Dissertation). University of Toronto. Retrieved from http://hdl.handle.net/1807/91233
Sheldon, C Tess. "Meds on the Menu: The Covert Administration of Psychotropic Medication to Adult Inpatients Determined to be Decisionally-Incapable in Ontario's Psychiatric Settings." 2015. Doctoral Dissertation, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/91233.
Sheldon, C Tess. "Meds on the Menu: The Covert Administration of Psychotropic Medication to Adult Inpatients Determined to be Decisionally-Incapable in Ontario's Psychiatric Settings." 2015. Web. 17 Jan 2021.
Sheldon CT. Meds on the Menu: The Covert Administration of Psychotropic Medication to Adult Inpatients Determined to be Decisionally-Incapable in Ontario's Psychiatric Settings. [Internet] [Doctoral dissertation]. University of Toronto; 2015. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/91233.
Sheldon CT. Meds on the Menu: The Covert Administration of Psychotropic Medication to Adult Inpatients Determined to be Decisionally-Incapable in Ontario's Psychiatric Settings. [Doctoral Dissertation]. University of Toronto; 2015. Available from: http://hdl.handle.net/1807/91233
3. Durbin, Anna. Mental Health Service Use Patterns for Immigrant Groups in Ontario: Population Based Studies.
► Background: Immigrants have diverse pre-immigration, peri-immigration, and post-immigration experiences. Despite being exposed to distinct mental health stressors, little is known about immigrant groups' service use… (more)
▼ Background: Immigrants have diverse pre-immigration, peri-immigration, and post-immigration experiences. Despite being exposed to distinct mental health stressors, little is known about immigrant groups' service use for non-psychotic mental health disorders in the host country.Objective: Three studies assessed mental health service use by recent newcomers who settled in Ontario, Canada compared to use by age-and-sex matched long term residents (Canadian-born individuals or pre-1985 immigrants). Each study focused on one factor associated with one of the three stages of immigration: pre-immigration (region of origin), peri-immigration (admission class), and post-immigration (area material deprivation).Methods: Population-based administrative data sources were linked to measure primary care visits, psychiatrist visits, and hospital use (i.e., emergency department visits or hospital admissions) for non-psychotic disorders by recent immigrants (i.e., within five years of arrival)in Ontario during 1993-2012. Results: Immigrants' service use patterns for non-psychotic mental health disorders differed from long term residents, with immigrants generally using less mental health care. In the pre-immigration study on world region of origin, immigrants from all regions used less psychiatry and hospital services than long term residents, while immigrants' use of primary care relative to long term residents varied by region of origin.In the peri-immigration study on admission class, male refugees were more likely to use primary care than long term residents. No admission class of immigrants had greater use of psychiatry or hospital care than comparators. In the post-immigration study on material deprivation, immigrants were over-represented in deprived areas. While residence in more deprived areas was associated with greater use of primary and hospital mental health care, immigrants exhibited smaller increases in use than long term residents.Discussion: Given rising immigration levels globally and Ontario, reviews of existing practices and policies are necessary to better understand immigrants' lower use of mental health service use and different patterns of use than long term residents. Advisors/Committee Members: Glazier, Richard H, Health Policy, Management and Evaluation.
Durbin, A. (2015). Mental Health Service Use Patterns for Immigrant Groups in Ontario: Population Based Studies . (Doctoral Dissertation). University of Toronto. Retrieved from http://hdl.handle.net/1807/69285
Durbin, Anna. "Mental Health Service Use Patterns for Immigrant Groups in Ontario: Population Based Studies." 2015. Doctoral Dissertation, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/69285.
Durbin, Anna. "Mental Health Service Use Patterns for Immigrant Groups in Ontario: Population Based Studies." 2015. Web. 17 Jan 2021.
Durbin A. Mental Health Service Use Patterns for Immigrant Groups in Ontario: Population Based Studies. [Internet] [Doctoral dissertation]. University of Toronto; 2015. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/69285.
Durbin A. Mental Health Service Use Patterns for Immigrant Groups in Ontario: Population Based Studies. [Doctoral Dissertation]. University of Toronto; 2015. Available from: http://hdl.handle.net/1807/69285
4. Salavati, Bahar. Which Siblings of Children with Cancer are Best Helped by Participating in a Specialized Intervention Program?.
To understand why some SCC experience psychological distress while others do not, researchers have turned their attention to potential protective factors that may influence the… (more)
To understand why some SCC experience psychological distress while others do not, researchers have turned their attention to potential protective factors that may influence the ability of SCC to cope with the cancer experience. Provision of protective/buffering factors specifically to less-resilient siblings (defined as those with higher initial depression and anxiety symptom scores) in the form of a structured program has not been previously attempted. The objective of this study was to explore outcomes of a specialized 8 week, intervention program for SCC. SCC and one parent completed standardized questionnaires exploring symptoms of depression and anxiety pre and post intervention. Results showed that the gender of the SCC, and the specific diagnosis of the child with cancer were factors significantly associated with the degree of reported symptoms of anxiety and depression respectively. Looking at significant interactions, we found that girls whose siblings had brain tumours improved less than other subgroups
Advisors/Committee Members: Barrera, Maru, Medical Science.
Subjects/Keywords: siblings; intervention; 0347
Salavati, B. (2012). Which Siblings of Children with Cancer are Best Helped by Participating in a Specialized Intervention Program? . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/32715
Salavati, Bahar. "Which Siblings of Children with Cancer are Best Helped by Participating in a Specialized Intervention Program?." 2012. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/32715.
Salavati, Bahar. "Which Siblings of Children with Cancer are Best Helped by Participating in a Specialized Intervention Program?." 2012. Web. 17 Jan 2021.
Salavati B. Which Siblings of Children with Cancer are Best Helped by Participating in a Specialized Intervention Program?. [Internet] [Masters thesis]. University of Toronto; 2012. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/32715.
Salavati B. Which Siblings of Children with Cancer are Best Helped by Participating in a Specialized Intervention Program?. [Masters Thesis]. University of Toronto; 2012. Available from: http://hdl.handle.net/1807/32715
5. Chohan, Leena A. A Survey of Professional Burnout and Depression among Pediatric Dentists in the United States.
Objectives: 1) To assess the prevalence of occupational burnout and depression among pediatric dentists in the United States, and 2) To explore for differences in… (more)
Objectives: 1) To assess the prevalence of occupational burnout and depression among pediatric dentists in the United States, and 2) To explore for differences in the prevalence of burnout/depression based upon gender, age, marital status, clinical practice type, geographical location, number of years in clinical practice, and number of hours worked per week. Methods: A self-administered online anonymous survey using Survey Monkey速 was sent to all active members of the American Academy of Pediatric Dentistry residing in the United States. The survey included: 1) demographic information; 2) the Maslach Burnout Inventory (MBI); and 3) the Patient Health Questionnaire 8 (PHQ-8). Results: A total of 4,735 pediatric dentists received the survey questionnaires and resulted in 540 usable responses (response rate = 11.40%). The prevalence of occupational burnout and depression were 9.1 and 7.2 percent respectively. Conclusions: A small but notable number of U.S. pediatric dentists had occupational burnout and depression.
Advisors/Committee Members: Nainar, Hashim, Dentistry.
Subjects/Keywords: Burnout; Depression; Pediatric Dentistry; 0347
Chohan, L. A. (2016). A Survey of Professional Burnout and Depression among Pediatric Dentists in the United States . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/74563
Chohan, Leena A. "A Survey of Professional Burnout and Depression among Pediatric Dentists in the United States." 2016. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/74563.
Chohan, Leena A. "A Survey of Professional Burnout and Depression among Pediatric Dentists in the United States." 2016. Web. 17 Jan 2021.
Chohan LA. A Survey of Professional Burnout and Depression among Pediatric Dentists in the United States. [Internet] [Masters thesis]. University of Toronto; 2016. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/74563.
Chohan LA. A Survey of Professional Burnout and Depression among Pediatric Dentists in the United States. [Masters Thesis]. University of Toronto; 2016. Available from: http://hdl.handle.net/1807/74563
6. Rabin, Rachel Allison. Effects of Cannabis Dependence on Cognitive Function in Males with Schizophrenia.
Background: Cognitive impairment and cannabis use are common among patients with schizophrenia. However, the moderating role of cannabis on cognition remains unclear. Aim: We sought… (more)
Background: Cognitive impairment and cannabis use are common among patients with schizophrenia. However, the moderating role of cannabis on cognition remains unclear. Aim: We sought to examine cognition and symptomatology as a function of cannabis use patterns in schizophrenia. Methodology: Cognition was assessed in male outpatients with current cannabis dependence (n=18), historical cannabis dependence (n=21) and patients with no lifetime use (n=8). In addition, we explored the relationship between cumulative cannabis exposure and cognition among lifetime users. Results: Lifetime cannabis users demonstrated better processing speed than patients with no lifetime use. Notably, patients with current dependence exhibited robust relationships between cumulative cannabis exposure and cognition; associations were absent in former users. Conclusions: Cannabis status has minimal effects on cognition in schizophrenia. However, cumulative cannabis exposure significantly impairs cognition in current, but not former users, suggesting that the state dependent negative effects of cannabis may be reversed with sustained abstinence.
Advisors/Committee Members: George, Tony Peter, Medical Science.
Subjects/Keywords: schizophrenia; addiction; 0347; 0633
Rabin, R. A. (2011). Effects of Cannabis Dependence on Cognitive Function in Males with Schizophrenia . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/31399
Rabin, Rachel Allison. "Effects of Cannabis Dependence on Cognitive Function in Males with Schizophrenia." 2011. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/31399.
Rabin, Rachel Allison. "Effects of Cannabis Dependence on Cognitive Function in Males with Schizophrenia." 2011. Web. 17 Jan 2021.
Rabin RA. Effects of Cannabis Dependence on Cognitive Function in Males with Schizophrenia. [Internet] [Masters thesis]. University of Toronto; 2011. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/31399.
Rabin RA. Effects of Cannabis Dependence on Cognitive Function in Males with Schizophrenia. [Masters Thesis]. University of Toronto; 2011. Available from: http://hdl.handle.net/1807/31399
7. Zarei, Shadi. Tele-Mindfulness for Dementia's Family Caregivers: a Randomized Trial with a Usual Care Control Group.
Caring for a family member with dementia is associated with chronic stress which can have negative effects on caregivers' mental and physical health. Mindfulness-based interventions… (more)
Caring for a family member with dementia is associated with chronic stress which can have negative effects on caregivers' mental and physical health. Mindfulness-based interventions have been proposed to improve psychological outcomes in caregivers. The purpose of this study was to evaluate the feasibility and effectiveness of live online mindfulness (tele-MBCT) program for caregivers of people with dementia. 26 family caregivers were randomly assigned to a tele-MBCT intervention or control group. Intervention participants attended eight weekly live online training and practiced at home. All participants completed surveys at baseline, post-intervention and 4-week follow-up. Majority of participants completed the study. Intervention group reported high satisfaction with the intervention and the online delivery method. Pre-Post improvement in self-compassion and coping strategies in the intervention group were noted. Tele-MBCT is a feasible intervention and may improve psychological outcomes and adaptive coping in dementia's family caregivers. A larger controlled trial is warranted.
Advisors/Committee Members: Sadavoy, Joel, Medical Science.
Subjects/Keywords: Caregiver; Dementia; Mindfulness; 0347
Zarei, S. (2018). Tele-Mindfulness for Dementia's Family Caregivers: a Randomized Trial with a Usual Care Control Group . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/91463
Zarei, Shadi. "Tele-Mindfulness for Dementia's Family Caregivers: a Randomized Trial with a Usual Care Control Group." 2018. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/91463.
Zarei, Shadi. "Tele-Mindfulness for Dementia's Family Caregivers: a Randomized Trial with a Usual Care Control Group." 2018. Web. 17 Jan 2021.
Zarei S. Tele-Mindfulness for Dementia's Family Caregivers: a Randomized Trial with a Usual Care Control Group. [Internet] [Masters thesis]. University of Toronto; 2018. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/91463.
Zarei S. Tele-Mindfulness for Dementia's Family Caregivers: a Randomized Trial with a Usual Care Control Group. [Masters Thesis]. University of Toronto; 2018. Available from: http://hdl.handle.net/1807/91463
8. Klopfer, Kristina Monika. The Association of Childhood Trauma, Eating Disorder Symptoms and General Psychopathology in Individuals with Eating Disorders.
The purpose of this study was to investigate the influence of childhood sexual, physical and emotional abuse and childhood emotional and physical neglect on eating… (more)
The purpose of this study was to investigate the influence of childhood sexual, physical and emotional abuse and childhood emotional and physical neglect on eating disorder symptoms and general psychopathology. This study utilized a cross-sectional research design incorporating a combination of self-report measures and clinical interviews. Seventy participants were recruited from two eating disorder treatment centres. A series of univariate tests revealed no significant differences between individuals who reported a mild level of trauma and those who reported a severe level of trauma on all clinical measures. Logistic regression analyses revealed associations between impulsivity and childhood physical abuse and between psychiatric comorbidity and childhood physical neglect. Few associations were found and the observed effect sizes were generally small suggesting that the null findings were not due to inadequate power. It may be that the study sample differed from those used in previous investigations in which significant associations have been documented.
Advisors/Committee Members: Woodside, Blake, Medical Science.
Subjects/Keywords: eating disorders; childhood trauma; 0347
Klopfer, K. M. (2011). The Association of Childhood Trauma, Eating Disorder Symptoms and General Psychopathology in Individuals with Eating Disorders . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/27348
Klopfer, Kristina Monika. "The Association of Childhood Trauma, Eating Disorder Symptoms and General Psychopathology in Individuals with Eating Disorders." 2011. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/27348.
Klopfer, Kristina Monika. "The Association of Childhood Trauma, Eating Disorder Symptoms and General Psychopathology in Individuals with Eating Disorders." 2011. Web. 17 Jan 2021.
Klopfer KM. The Association of Childhood Trauma, Eating Disorder Symptoms and General Psychopathology in Individuals with Eating Disorders. [Internet] [Masters thesis]. University of Toronto; 2011. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/27348.
Klopfer KM. The Association of Childhood Trauma, Eating Disorder Symptoms and General Psychopathology in Individuals with Eating Disorders. [Masters Thesis]. University of Toronto; 2011. Available from: http://hdl.handle.net/1807/27348
9. Vaccarino, Oriana. Social Anxiety Disorder: Behavioural Characteristics Associated with the Cortisol Stress Response.
The present study evaluated the cortisol stress response and its relationship to several behavioural measures in SAD participants. It is hypothesized that SAD participants will… (more)
The present study evaluated the cortisol stress response and its relationship to several behavioural measures in SAD participants. It is hypothesized that SAD participants will show an exaggerated cortisol response to the Trier Social Stress Test (TSST) and differing positive and negative affects compared to controls, as well as correlations between the two measures. SAD (n=12) and controls (n=12) underwent the TSST. Serial plasma cortisol samples were taken and self-report measures were completed. The plasma cortisol levels were numerically higher in SAD at all time points compared to controls but the difference was not statistically significant. Cortisol response correlated inversely with childhood emotional abuse (p=0.01) and directly with positive affect (p=0.02) in SAD participants. Furthermore, SAD participants reported greater negative affect (prior to and after TSST) and more frequent emotional abuse than controls. SAD is associated with changes in HPA axis activity and affective states that differ from controls.
Advisors/Committee Members: Ravindran, Arun, Medical Science.
Subjects/Keywords: Social Anxiety; Stress; Cortisol; 0347
Vaccarino, O. (2013). Social Anxiety Disorder: Behavioural Characteristics Associated with the Cortisol Stress Response . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/43323
Vaccarino, Oriana. "Social Anxiety Disorder: Behavioural Characteristics Associated with the Cortisol Stress Response." 2013. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/43323.
Vaccarino, Oriana. "Social Anxiety Disorder: Behavioural Characteristics Associated with the Cortisol Stress Response." 2013. Web. 17 Jan 2021.
Vaccarino O. Social Anxiety Disorder: Behavioural Characteristics Associated with the Cortisol Stress Response. [Internet] [Masters thesis]. University of Toronto; 2013. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/43323.
Vaccarino O. Social Anxiety Disorder: Behavioural Characteristics Associated with the Cortisol Stress Response. [Masters Thesis]. University of Toronto; 2013. Available from: http://hdl.handle.net/1807/43323
10. Shirazi, Nikoo. Perfectionism and Generalized Anxiety Disorder: Investigating the Mediating Effect of Emotion Dysregulation.
The present study examined the associations among perfectionism, emotion dysregulation, and GAD. Eighty participants completed self-report questionnaires assessing perfectionistic tendencies, difficulties in emotion regulation, and… (more)
The present study examined the associations among perfectionism, emotion dysregulation, and GAD. Eighty participants completed self-report questionnaires assessing perfectionistic tendencies, difficulties in emotion regulation, and symptoms of GAD. The purpose of this study was to examine emotion dysregulation as a potential mediator in the relationship between perfectionism and GAD. Results indicated that general emotion dysregulation statistically mediated the relationship between the socially prescribed dimension of perfectionism and GAD. In addition, specific difficulties in emotion regulation, including deficits in acceptance of emotions, emotional clarity, impulse control, and access to effective regulation strategies, fully mediated the association between socially prescribed perfectionism and GAD symptoms. Implications for treatment and future research directions are discussed.
Advisors/Committee Members: Watson, Jeanne, Applied Psychology and Human Development.
Subjects/Keywords: Emotion Dysregulation; Generalized Anxiety Disorder; Perfectionism; 0347
Shirazi, N. (2016). Perfectionism and Generalized Anxiety Disorder: Investigating the Mediating Effect of Emotion Dysregulation . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/71703
Shirazi, Nikoo. "Perfectionism and Generalized Anxiety Disorder: Investigating the Mediating Effect of Emotion Dysregulation." 2016. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/71703.
Shirazi, Nikoo. "Perfectionism and Generalized Anxiety Disorder: Investigating the Mediating Effect of Emotion Dysregulation." 2016. Web. 17 Jan 2021.
Shirazi N. Perfectionism and Generalized Anxiety Disorder: Investigating the Mediating Effect of Emotion Dysregulation. [Internet] [Masters thesis]. University of Toronto; 2016. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/71703.
Shirazi N. Perfectionism and Generalized Anxiety Disorder: Investigating the Mediating Effect of Emotion Dysregulation. [Masters Thesis]. University of Toronto; 2016. Available from: http://hdl.handle.net/1807/71703
11. Nachman, Alex. Mental Health Outcomes in Survivors of Childhood Cancer.
The current literature surrounding their mental health outcomes is limited. This study addresses limitations in the field by using healthcare administrative databases to compare the… (more)
The current literature surrounding their mental health outcomes is limited. This study addresses limitations in the field by using healthcare administrative databases to compare the rates of mental health care utilization and the risk for a severe mental health episode between pediatric cancer survivors and matched population controls. Additionally, this study assesses the impact of demographic, disease, and treatment level predictors on mental health outcomes. Overall, pediatric cancer survivors were more likely to utilize mental health care (Adjusted Rate Ratio 1.31, 95% CI 1.16-1.48), but were not at greater risk of severe mental health episodes (Hazard Ratio 1.11 95% CI, 0.99-1.25). Pediatric cancer survivors were identified to be at increased risk of mood/affective disorders and psychotic disorders. In general, predictors of mental health outcomes in survivors were similar to those in the general population. This study provides novel information to a limited field, and a strong platform for future studies.
Advisors/Committee Members: Nathan, Paul, Medical Science.
Subjects/Keywords: mental health; pediatric cancer; survivorship; 0347
Nachman, A. (2016). Mental Health Outcomes in Survivors of Childhood Cancer . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/75822
Nachman, Alex. "Mental Health Outcomes in Survivors of Childhood Cancer." 2016. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/75822.
Nachman, Alex. "Mental Health Outcomes in Survivors of Childhood Cancer." 2016. Web. 17 Jan 2021.
Nachman A. Mental Health Outcomes in Survivors of Childhood Cancer. [Internet] [Masters thesis]. University of Toronto; 2016. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/75822.
Nachman A. Mental Health Outcomes in Survivors of Childhood Cancer. [Masters Thesis]. University of Toronto; 2016. Available from: http://hdl.handle.net/1807/75822
12. Blumberger, Daniel. A Randomized Double Blind Sham-controlled Comparison of Bilateral and Unilateral Repetitive Transcranial Magnetic Stimulation for Treatment-resistant Major Depression.
Objectives: High frequency left-sided (HFL) and low frequency right-sided (LFR) unilateral repetitive transcranial magnetic stimulation (rTMS) are efficacious in treatment-resistant major depression (TRD). Similar benefit… (more)
Objectives: High frequency left-sided (HFL) and low frequency right-sided (LFR) unilateral repetitive transcranial magnetic stimulation (rTMS) are efficacious in treatment-resistant major depression (TRD). Similar benefit has been suggested for sequential bilateral rTMS (LFR then HFL). Therefore, this study evaluated the efficacy of HFL and sequential bilateral rTMS compared to sham in TRD. Methods: Seventy-four subjects between the ages of 18 and 85 with TRD and a 17-item Hamilton Depression Rating Scale (HDRS) greater than 21 were randomized to receive unilateral, bilateral, or sham rTMS. Remission rates were compared among the three groups. Results: Remission rates differed significantly among the three groups. The remission rate was significantly higher in the bilateral group (34.6%) than the unilateral (4.5%) and sham (5.0%) groups. The remission rate in the unilateral group did not differ from sham group. Conclusion: These findings warrant larger controlled studies that compare the efficacy of sequential bilateral rTMS and HFL rTMS in TRD.
Advisors/Committee Members: Daskalakis, Zafiris Jeff, Medical Science.
Subjects/Keywords: Depression; TMS; Treatment-Resistance; 0347; 0317
Blumberger, D. (2011). A Randomized Double Blind Sham-controlled Comparison of Bilateral and Unilateral Repetitive Transcranial Magnetic Stimulation for Treatment-resistant Major Depression . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/32917
Blumberger, Daniel. "A Randomized Double Blind Sham-controlled Comparison of Bilateral and Unilateral Repetitive Transcranial Magnetic Stimulation for Treatment-resistant Major Depression." 2011. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/32917.
Blumberger, Daniel. "A Randomized Double Blind Sham-controlled Comparison of Bilateral and Unilateral Repetitive Transcranial Magnetic Stimulation for Treatment-resistant Major Depression." 2011. Web. 17 Jan 2021.
Blumberger D. A Randomized Double Blind Sham-controlled Comparison of Bilateral and Unilateral Repetitive Transcranial Magnetic Stimulation for Treatment-resistant Major Depression. [Internet] [Masters thesis]. University of Toronto; 2011. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/32917.
Blumberger D. A Randomized Double Blind Sham-controlled Comparison of Bilateral and Unilateral Repetitive Transcranial Magnetic Stimulation for Treatment-resistant Major Depression. [Masters Thesis]. University of Toronto; 2011. Available from: http://hdl.handle.net/1807/32917
13. Kennedy, Tara. Exploring the Influence of Optimism and Self-efficacy on New and Professional Immigrants' Retraining Experiences in Canada.
The purpose of this study was to examine the retraining and career development experiences of new and professional immigrants in Canada. The study intended to… (more)
The purpose of this study was to examine the retraining and career development experiences of new and professional immigrants in Canada. The study intended to provide an in- depth perspective into the influence of immigrants' optimism and self-efficacy on their retraining and career development experiences. Using a qualitative methodology, in-depth interviews were conducted and a grounded theory approach was employed to analyze the data. Central themes within participant narratives emerged and key results were introduced. Participants' experiences included a myriad of barriers and challenges, yet many viewed this experience as a positive opportunity for growth and development. The results explored differences between optimists' and pessimists' retraining and career development experiences, as well as the role of self-efficacy within immigrants' career development. Results have implications for career and vocational psychology literature, practice, and career counselling, and include suggestions for future researchers.
Advisors/Committee Members: Chen, Charles, Adult Education and Counselling Psychology.
Subjects/Keywords: Immigrants; Retraining; Optimism; Self-Efficacy; 0621; 0347
Kennedy, T. (2012). Exploring the Influence of Optimism and Self-efficacy on New and Professional Immigrants' Retraining Experiences in Canada . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/32445
Kennedy, Tara. "Exploring the Influence of Optimism and Self-efficacy on New and Professional Immigrants' Retraining Experiences in Canada." 2012. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/32445.
Kennedy, Tara. "Exploring the Influence of Optimism and Self-efficacy on New and Professional Immigrants' Retraining Experiences in Canada." 2012. Web. 17 Jan 2021.
Kennedy T. Exploring the Influence of Optimism and Self-efficacy on New and Professional Immigrants' Retraining Experiences in Canada. [Internet] [Masters thesis]. University of Toronto; 2012. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/32445.
Kennedy T. Exploring the Influence of Optimism and Self-efficacy on New and Professional Immigrants' Retraining Experiences in Canada. [Masters Thesis]. University of Toronto; 2012. Available from: http://hdl.handle.net/1807/32445
14. Francis, Philip. Neuroanatomical Correlates of Depressive Symptoms Following Acute Ischemic Stroke.
This study investigated the hypothesis that severity of depressive symptoms following acute ischemic stroke is associated with degree of tissue infarction and severity of white… (more)
This study investigated the hypothesis that severity of depressive symptoms following acute ischemic stroke is associated with degree of tissue infarction and severity of white matter changes (WMCs). It employed a novel quantitative region-based approach considering both infarction and WMCs. Of 54 ischemic stroke patients recruited, 50 (72.3 ± 12.8 years, 52.0% male) had useable CT scans. The typical patient was recruited within 3 weeks of their stroke (19.7 ± 31.0 days), exhibited minor cognitive impairment (MMSE score 25.8 ± 4.6), and had mild to moderate stroke severity (NIHSS score 6.5 ± 5.4). 28.0% of patients screened positive for clinical depression with a CES-D score ≥16. While neither degree of infarction nor severity of WMCs (ARWMC score) in the 12 brain regions correlated with depressive symptoms (CES-D score), stroke severity was a significant predictor of depressive symptoms. This stressor, related to physical disability, was a predominant predictor over lesion characteristics.
Advisors/Committee Members: t, Kris, Pharmacology.
Subjects/Keywords: stroke; depression; neuroimaging; CT; 0419; 0347; 0574
Francis, P. (2011). Neuroanatomical Correlates of Depressive Symptoms Following Acute Ischemic Stroke . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/29546
Francis, Philip. "Neuroanatomical Correlates of Depressive Symptoms Following Acute Ischemic Stroke." 2011. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/29546.
Francis, Philip. "Neuroanatomical Correlates of Depressive Symptoms Following Acute Ischemic Stroke." 2011. Web. 17 Jan 2021.
Francis P. Neuroanatomical Correlates of Depressive Symptoms Following Acute Ischemic Stroke. [Internet] [Masters thesis]. University of Toronto; 2011. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/29546.
Francis P. Neuroanatomical Correlates of Depressive Symptoms Following Acute Ischemic Stroke. [Masters Thesis]. University of Toronto; 2011. Available from: http://hdl.handle.net/1807/29546
15. Taylor, Danielle L. Pharmacogenetic Analysis of Glutamate System Gene Variants and Clinical Response to Clozapine.
Altered glutamatergic neurotransmission is implicated in schizophrenia etiology and response to the atypical antipsychotic clozapine. Response to clozapine is highly variable and partly depends on… (more)
Altered glutamatergic neurotransmission is implicated in schizophrenia etiology and response to the atypical antipsychotic clozapine. Response to clozapine is highly variable and partly depends on genetic factors as indicated by twin studies. The association of 17 glutamate system gene variants and clinical response to clozapine was investigated in a sample of European schizophrenia/schizoaffective patients deemed resistant/intolerant to previous pharmacotherapy. Categorical and continuous response measures were assessed following six months of clozapine treatment using change in Brief Psychiatric Rating Scale Scores, and were analyzed using Pearsonâ s chi-squared test or analysis of covariance, respectively. No significant associations were observed for all analyses after correction for multiple testing. Prior to correction, several nominally significant associations were observed, the most notable being between the SLC6A9 rs16831558 variant and change in positive symptoms (puncorrected=0.008, pcorrected=0.08). This finding warrants further investigation in larger well-characterized samples to clarify the role of SLC6A9 in clinical response to clozapine.
Advisors/Committee Members: Kennedy, James L, Medical Science.
Subjects/Keywords: Clozapine; Glutamate; Pharmacogenetics; Schizophrenia; Treatment Response; 0347
Taylor, D. L. (2015). Pharmacogenetic Analysis of Glutamate System Gene Variants and Clinical Response to Clozapine . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/74459
Taylor, Danielle L. "Pharmacogenetic Analysis of Glutamate System Gene Variants and Clinical Response to Clozapine." 2015. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/74459.
Taylor, Danielle L. "Pharmacogenetic Analysis of Glutamate System Gene Variants and Clinical Response to Clozapine." 2015. Web. 17 Jan 2021.
Taylor DL. Pharmacogenetic Analysis of Glutamate System Gene Variants and Clinical Response to Clozapine. [Internet] [Masters thesis]. University of Toronto; 2015. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/74459.
Taylor DL. Pharmacogenetic Analysis of Glutamate System Gene Variants and Clinical Response to Clozapine. [Masters Thesis]. University of Toronto; 2015. Available from: http://hdl.handle.net/1807/74459
16. Farrokhi, Farhat. A Patient Opinion Survey to Identify Perceived Barriers to the Introduction of a Screening Program for Depression in a Hemodialysis Population.
Patient-related barriers may reduce the effectiveness of screening for depression. This study aimed to explore perceived barriers to participation in a Screening Program for Depression… (more)
Patient-related barriers may reduce the effectiveness of screening for depression. This study aimed to explore perceived barriers to participation in a Screening Program for Depression by hemodialysis patients. In a cross-sectional study of hemodialysis patients, the Perceived Barriers to Psychological Treatment questionnaire was used to measure barriers to the Screening Program. Of 160 participants, 73.1% perceived at least one barrier (95% CI, 66.2% to 80.0%). The most common barriers were concerns about the side effects of antidepressant medications (40%), concerns about having more medications (32%), feeling that the problem is not severe enough (23%), and perceiving no risk of depression (23%). A high depression score was an independent predictor of barriers related to perceiving no benefit of the Screening Program and psychological, social, and practical barriers. We believe that patient-related barriers need to be addressed before implementing any case identification and treatment program for depression.
Advisors/Committee Members: Logan, Alexander, Health Policy, Management and Evaluation.
Subjects/Keywords: Depression; Barriers; Screening; Hemodialysis; 0766; 0347
Farrokhi, F. (2013). A Patient Opinion Survey to Identify Perceived Barriers to the Introduction of a Screening Program for Depression in a Hemodialysis Population . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/35118
Farrokhi, Farhat. "A Patient Opinion Survey to Identify Perceived Barriers to the Introduction of a Screening Program for Depression in a Hemodialysis Population." 2013. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/35118.
Farrokhi, Farhat. "A Patient Opinion Survey to Identify Perceived Barriers to the Introduction of a Screening Program for Depression in a Hemodialysis Population." 2013. Web. 17 Jan 2021.
Farrokhi F. A Patient Opinion Survey to Identify Perceived Barriers to the Introduction of a Screening Program for Depression in a Hemodialysis Population. [Internet] [Masters thesis]. University of Toronto; 2013. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/35118.
Farrokhi F. A Patient Opinion Survey to Identify Perceived Barriers to the Introduction of a Screening Program for Depression in a Hemodialysis Population. [Masters Thesis]. University of Toronto; 2013. Available from: http://hdl.handle.net/1807/35118
17. Shah, Parita. Classifying Schizophrenia Based on Response to Antipsychotic Medications.
Clozapine is the main treatment for patients with significant psychotic symptoms despite adequate trials of non-clozapine antipsychotics. However, 40-70% of patients show suboptimal response to… (more)
Clozapine is the main treatment for patients with significant psychotic symptoms despite adequate trials of non-clozapine antipsychotics. However, 40-70% of patients show suboptimal response to clozapine. We aimed to: (1) examine the relationship between delay in initiating clozapine and treatment outcomes through a literature review; (2) examine clozapine response/non-response trajectories and predictors of long-term non-response through a retrospective chart review; and (3) determine the relationships between glutamatergic neurometabolites and cortical thickness through a cross-sectional imaging study. Delay in initiating clozapine and number of hospitalizations were associated with poor clozapine response. Further, response trajectories ranged from sustained response or non-response to developed response or non-response. Finally, glutamatergic neurometabolite levels in the dorsal anterior cingulate cortex were associated with cortical thinning in the right prefrontal cortex in patients with treatment-resistant schizophrenia, independent of age, sex, treatment, and illness severity. This work advances our understanding of treatment-resistant schizophrenia from clinical and neuropathological perspectives.
Advisors/Committee Members: Graff-Guerrero, Ariel, Gerretsen, Philip, Medical Science.
Subjects/Keywords: Clozapine; Outcomes; Predictors; Psychosis; Response; Schizophrenia; 0347
Shah, P. (2019). Classifying Schizophrenia Based on Response to Antipsychotic Medications . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/103056
Shah, Parita. "Classifying Schizophrenia Based on Response to Antipsychotic Medications." 2019. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/103056.
Shah, Parita. "Classifying Schizophrenia Based on Response to Antipsychotic Medications." 2019. Web. 17 Jan 2021.
Shah P. Classifying Schizophrenia Based on Response to Antipsychotic Medications. [Internet] [Masters thesis]. University of Toronto; 2019. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/103056.
Shah P. Classifying Schizophrenia Based on Response to Antipsychotic Medications. [Masters Thesis]. University of Toronto; 2019. Available from: http://hdl.handle.net/1807/103056
18. Plahouras, Joanne Elena. Clinical Outcomes and Capacity to Consent to Electroconvulsive Therapy in Patients with Schizophrenia and Patient Experience with Legally Mandated Treatment.
Background: Schizophrenia is one of the most debilitating psychiatric illnesses and affects 1% of people globally. Objectives: To evaluate the experiences of patients with schizophrenia… (more)
Background: Schizophrenia is one of the most debilitating psychiatric illnesses and affects 1% of people globally. Objectives: To evaluate the experiences of patients with schizophrenia who were legally mandated to treatment. To evaluate the clinical outcomes for incapable and capable patients with schizophrenia who were treated with electroconvulsive therapy (ECT). Methods: For the first objective, we searched 4 electronic bibliographic databases and completed a systematic review of qualitative studies. For the second objective, we completed a chart review of all inpatients with schizophrenia who were treated with at least one acute course of ECT. Results: Patients who were legally mandated to receive treatment reported both positive and negative experiences. Incapable and capable patients experienced treatment response with limited cognitive impairment. Conclusions: Addressing patients' concerns could lead to better attitudes towards legally mandated treatment. ECT appears to be a safe and effective procedure regardless of capacity status.
Advisors/Committee Members: Blumberger, Daniel M, Medical Science.
Subjects/Keywords: Electroconvulsive Therapy; Legally Mandated Treatment; Schizophrenia; 0347
Plahouras, J. E. (2020). Clinical Outcomes and Capacity to Consent to Electroconvulsive Therapy in Patients with Schizophrenia and Patient Experience with Legally Mandated Treatment . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/103234
Plahouras, Joanne Elena. "Clinical Outcomes and Capacity to Consent to Electroconvulsive Therapy in Patients with Schizophrenia and Patient Experience with Legally Mandated Treatment." 2020. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/103234.
Plahouras, Joanne Elena. "Clinical Outcomes and Capacity to Consent to Electroconvulsive Therapy in Patients with Schizophrenia and Patient Experience with Legally Mandated Treatment." 2020. Web. 17 Jan 2021.
Plahouras JE. Clinical Outcomes and Capacity to Consent to Electroconvulsive Therapy in Patients with Schizophrenia and Patient Experience with Legally Mandated Treatment. [Internet] [Masters thesis]. University of Toronto; 2020. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/103234.
Plahouras JE. Clinical Outcomes and Capacity to Consent to Electroconvulsive Therapy in Patients with Schizophrenia and Patient Experience with Legally Mandated Treatment. [Masters Thesis]. University of Toronto; 2020. Available from: http://hdl.handle.net/1807/103234
19. Bird, Elizabeth Atik. The Percy Papers.
The Indian Residential School era took its toll on the health and wellbeing of the entire Indigenous population in Canada. How does one rehabilitate after… (more)
The Indian Residential School era took its toll on the health and wellbeing of the entire Indigenous population in Canada. How does one rehabilitate after suffering tremendous loss of culture, language, voice, and self? My father, Percy James Bird, spent 15 years in an Indian Residential School. He then worked nineteen years with the federal government. After retirement, he took a creative writing course, producing 21 stories. A critical read of the stories, using Indigenous story telling methods, begins the process of tearing down a negative colonized version of Percy. As a silent survivor, his stories diffuse much of the violence from his past. The objective of this rehabilitation science inquiry is to use an Indigenous storywork research approach to explore patterns of healing and examine how Percy's personal healing led to his later aspirations to create systems of healing for his people.
Advisors/Committee Members: Nixon, Stephanie, Rehabilitation Science.
Subjects/Keywords: Health; Indian Residential School; Indigenous; Storywork; 0347
Bird, E. A. (2020). The Percy Papers . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/103455
Bird, Elizabeth Atik. "The Percy Papers." 2020. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/103455.
Bird, Elizabeth Atik. "The Percy Papers." 2020. Web. 17 Jan 2021.
Bird EA. The Percy Papers. [Internet] [Masters thesis]. University of Toronto; 2020. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/103455.
Bird EA. The Percy Papers. [Masters Thesis]. University of Toronto; 2020. Available from: http://hdl.handle.net/1807/103455
20. Reid, Nadine. A Realist Evaluation of Family Navigation in Youth Mental Health and Addictions.
► In Canada today, many families of youth with mental health and/or addiction concerns are struggling to access the care they need. The Family Navigation Project… (more)
▼ In Canada today, many families of youth with mental health and/or addiction concerns are struggling to access the care they need. The Family Navigation Project is a service affiliated with Sunnybrook Health Sciences Centre in Toronto, Ontario, which aims to provide needs-based, family-centred system navigation to families of youth aged 13 to 26 with mental health and/or addiction concerns. The current study is a Realist Evaluation of the Family Navigation Project. The objectives of this study were a) to describe the population being served by the Family Navigation Project; b) to develop a conceptual framework for family navigation and a program theory for the Family Navigation Project; and c) to test the program theory, and refine it based on the results. This multi-phase, mixed methods study applied a Realist Evaluation framework and a cross-sectional methodological design in which both quantitative and qualitative data were collected through an online survey package in order to evaluate the sample characteristics; perception of navigation; the impact of perceived experience on family empowerment, family quality of life, and service satisfaction; and the influence of context. Data was collected from a convenience sample of 134 families seeking care on behalf of youth, who were registered with the Family Navigation Project at the time of the study. Descriptive, inferential and qualitative analyses were performed. Results indicated that the Family Navigation Project reached its target population in this sample; that families in this sample were highly satisfied with the services they received; that most families in this sample perceived care to be accessible, continuous, and family-inclusive; that this perceived experience significantly influenced family empowerment, family quality of life, and service satisfaction; and that both individual and systemic-level contexts influence experience and outcomes to varying extents. The conceptual framework and program theory were subsequently refined. Applications, contributions and limitations are noted. Advisors/Committee Members: Cockerill, Rhonda, Durbin, Janet, Health Policy, Management and Evaluation.
Subjects/Keywords: Evaluation; Families; Mental health; Navigation; Youth; 0347
Reid, N. (2017). A Realist Evaluation of Family Navigation in Youth Mental Health and Addictions . (Doctoral Dissertation). University of Toronto. Retrieved from http://hdl.handle.net/1807/80976
Reid, Nadine. "A Realist Evaluation of Family Navigation in Youth Mental Health and Addictions." 2017. Doctoral Dissertation, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/80976.
Reid, Nadine. "A Realist Evaluation of Family Navigation in Youth Mental Health and Addictions." 2017. Web. 17 Jan 2021.
Reid N. A Realist Evaluation of Family Navigation in Youth Mental Health and Addictions. [Internet] [Doctoral dissertation]. University of Toronto; 2017. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/80976.
Reid N. A Realist Evaluation of Family Navigation in Youth Mental Health and Addictions. [Doctoral Dissertation]. University of Toronto; 2017. Available from: http://hdl.handle.net/1807/80976
21. George, Miriam. Sri Lankan Tamil Diaspora: Contextualizing Pre-migration and Post- migration Traumatic Events and Psychological Distress.
The objective of this study was to generate a deeper understanding of the influence of pre- and post-migration traumatic experiences on refugees' psychological distress, including… (more)
The objective of this study was to generate a deeper understanding of the influence of pre- and post-migration traumatic experiences on refugees' psychological distress, including historical, political and social factors. This dissertation used a multi-method design to examine the impact of trauma on the psychological well-being of refugees. Further, the design included a qualitative component to provide a contextual framework for understanding refugee psychological distress that is not limited to an analysis of a disease model alone but by also making connections to important historical, social and political events. Post-Colonial, Refugee, Trauma and Feminist theories are used as analytic lenses to explain the social structures and events contributing to refugees' pre- and post-migration traumatic events, and psychological distress. This was an international study that spanned two continents. Sampling included 50 Sri Lankan Tamil refugee participants who lived in Chennai, India and 50 Sri Lankan refugees in Toronto, Canada. Inclusion criteria included a residency period of the last 12 months in either of the sampling sites, and participants 18 years of age or older. Participants from Toronto were recruited through social service agencies and associations, and participants from Chennai were recruited from refugee camps, and the Organization for Elam Refugee Rehabilitation. Tamil versions of the Harvard Trauma Questionnaire, the Post-Migration Living Difficulties Questionnaire, and the Symptoms Check List – 90R were utilized to measure participants' pre- and post-migration traumatic events and psychological distress. The Harvard Trauma Questionnaire contained qualitative open-ended questions to triangulate the quantitative data in identifying and exploring the impact of contextual influences. Results showed that post-migration traumatic event scores positively predicted psychological distress, and refugee claimants living in Canada had the highest scores on pre-migration and post-migration scores. The qualitative analysis revealed themes related to civil war and resettlement as significant issues. Implications of these findings support the development of a multi-level approach within social work practice which emphasizes contextual issues, focuses on individuals, and promotes social advocacy. Recommendations for future research point to conducting longitudinal studies to assess the cumulative effects of historical, social and political factors on refugees and identify resiliencies that mobilize their capacity to survive.
Advisors/Committee Members: Alaggia, Ramona, Social Work.
Subjects/Keywords: 0452; 0347; 0452
George, M. (2009). Sri Lankan Tamil Diaspora: Contextualizing Pre-migration and Post- migration Traumatic Events and Psychological Distress . (Doctoral Dissertation). University of Toronto. Retrieved from http://hdl.handle.net/1807/19270
George, Miriam. "Sri Lankan Tamil Diaspora: Contextualizing Pre-migration and Post- migration Traumatic Events and Psychological Distress." 2009. Doctoral Dissertation, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/19270.
George, Miriam. "Sri Lankan Tamil Diaspora: Contextualizing Pre-migration and Post- migration Traumatic Events and Psychological Distress." 2009. Web. 17 Jan 2021.
George M. Sri Lankan Tamil Diaspora: Contextualizing Pre-migration and Post- migration Traumatic Events and Psychological Distress. [Internet] [Doctoral dissertation]. University of Toronto; 2009. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/19270.
George M. Sri Lankan Tamil Diaspora: Contextualizing Pre-migration and Post- migration Traumatic Events and Psychological Distress. [Doctoral Dissertation]. University of Toronto; 2009. Available from: http://hdl.handle.net/1807/19270
22. Koltai, Jonathan Tomas. Socioeconomic Status, Stress Exposure, and Psychological Well-Being: Complexities in the Stress Process.
► Decades of research has established an inverse association between socioeconomic position and psychological distress. Within medical sociology, the stress process model represents a dominant framework… (more)
▼ Decades of research has established an inverse association between socioeconomic position and psychological distress. Within medical sociology, the stress process model represents a dominant framework for investigating mechanisms that generate emotional inequality. Central to the stress process perspective is the observation that exposure to social stress is fundamentally rooted in social statuses and the social roles individuals occupy in their daily lives. Historically, research guided by the stress process paradigm has demonstrated that disparities in psychological distress arise to a substantial degree from inequalities in stress exposure—individuals placed lower in the socioeconomic hierarchy, for instance, are exposed to higher levels of cumulative and operant life stress, and this translates into mental health disadvantages. This dissertation moves beyond existing research by identifying circumstances under which socioeconomic patterns in mental health do not conform to what is commonly predicted by traditional hypotheses, and also provides theoretical insights and empirical evidence about the dynamics that generate pockets of complexity in social stress research. Three major findings emerge. First, I present evidence that time-stable differences between individuals introduce a nontrivial amount of spuriousness in the association between income-related variables and mental health. This raises questions about the independent effect of current income dynamics over and above, for example, the array of disadvantages that individuals may face at more distal stages in the life course. Second, I demonstrate the ways that SES modifies the concurrent experience of job stressors and resources. My findings highlight conditions under which lower status workers are shielded from the effects of stressors, but also the ways that resources may actually leave higher status individuals more vulnerable to the effects of stress exposure. Third, I identify a subgroup of professionals for which a status-health paradox is observed—higher status workers experience poorer mental health relative to their lower status peers—and this can be explained by the stressors of higher status in this particular profession. Each study can be considered an independent project, but taken together they represent an overarching contribution to sociological understandings of the interplay between SES, stress exposure, and mental health. Advisors/Committee Members: Schieman, Scott, Sociology.
Subjects/Keywords: mental health; socioeconomic status; stress exposure; 0347
Koltai, J. T. (2018). Socioeconomic Status, Stress Exposure, and Psychological Well-Being: Complexities in the Stress Process . (Doctoral Dissertation). University of Toronto. Retrieved from http://hdl.handle.net/1807/89863
Koltai, Jonathan Tomas. "Socioeconomic Status, Stress Exposure, and Psychological Well-Being: Complexities in the Stress Process." 2018. Doctoral Dissertation, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/89863.
Koltai, Jonathan Tomas. "Socioeconomic Status, Stress Exposure, and Psychological Well-Being: Complexities in the Stress Process." 2018. Web. 17 Jan 2021.
Koltai JT. Socioeconomic Status, Stress Exposure, and Psychological Well-Being: Complexities in the Stress Process. [Internet] [Doctoral dissertation]. University of Toronto; 2018. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/89863.
Koltai JT. Socioeconomic Status, Stress Exposure, and Psychological Well-Being: Complexities in the Stress Process. [Doctoral Dissertation]. University of Toronto; 2018. Available from: http://hdl.handle.net/1807/89863
23. Fervaha, Gagandeep. Motivational Deficits in Schizophrenia.
► Reductions in drive and goal-directed behaviour have long been described as key features of schizophrenia. This thesis contains several investigations into the motivational deficits present… (more)
▼ Reductions in drive and goal-directed behaviour have long been described as key features of schizophrenia. This thesis contains several investigations into the motivational deficits present in people with schizophrenia. Despite not being required for the diagnosis, motivational deficits were found to be a highly prevalent feature of the disease, even among younger patients who were relatively early in their course of illness. Using cross-sectional and longitudinal follow-up study designs, and across two studies with different participants, motivational deficits were found to hold strong predictive value for the determination of functional outcomes. After establishing the importance of motivational deficits in terms of outcomes, underlying behavioural mechanisms were explored using experimental paradigms. Several candidate reward processes were examined concurrently, including valuation of outcomes, estimation of the costs associated with obtaining outcomes, and learning the association between actions and outcomes. Our results provide support for the proposal that individuals with schizophrenia have impairments in their ability to compute effort demands, and that these impairments translate into real-world reductions in goal-directed behaviour. Beyond mechanisms, this thesis also examined the inter-relationship between motivational deficits and another key domain of psychopathology in schizophrenia, namely, cognition. Although these two domains are thought of as distinct, two studies included in this thesis provide empirical evidence of an association, which is interpreted within a theoretical framework whereby poor motivation translates into reduced effort put forth during cognitive testing, which ultimately results in poorer submaximal test performance. Finally, the last study included in this thesis addresses the issue of treatment-induced symptoms. This study failed to find support for the contention that treatment with antipsychotic medications necessarily worsens the severity of motivational deficits in schizophrenia. Taken together, these investigations highlight the importance of motivational deficits in schizophrenia, and lay the foundation for a mechanistic understanding of these impairments. Advisors/Committee Members: Remington, Gary, Medical Science.
Subjects/Keywords: Apathy; Cognition; Motivation; Outcome; Psychosis; Schizophrenia; 0347
Fervaha, G. (2016). Motivational Deficits in Schizophrenia . (Doctoral Dissertation). University of Toronto. Retrieved from http://hdl.handle.net/1807/76393
Fervaha, Gagandeep. "Motivational Deficits in Schizophrenia." 2016. Doctoral Dissertation, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/76393.
Fervaha, Gagandeep. "Motivational Deficits in Schizophrenia." 2016. Web. 17 Jan 2021.
Fervaha G. Motivational Deficits in Schizophrenia. [Internet] [Doctoral dissertation]. University of Toronto; 2016. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/76393.
Fervaha G. Motivational Deficits in Schizophrenia. [Doctoral Dissertation]. University of Toronto; 2016. Available from: http://hdl.handle.net/1807/76393
24. Wang, Chen. Understanding Experiences and Support Needs of Families Caring for Older Adults with Depression.
Background: The experiences and needs of caregivers of older adults with depression are not well understood. This study aims to explore their experiences and desired… (more)
Background: The experiences and needs of caregivers of older adults with depression are not well understood. This study aims to explore their experiences and desired resources from the healthcare system. Methods: Eleven qualitative interviews were conducted with caregivers of older adults with a clinical depression diagnosis in Toronto, Canada. Findings were generated via thematic analysis. Findings: Caregivers perceived a transformation in the person with depression's behaviours and personality that also changed the relationship between them. Caregivers modified their lifestyle, perceived stigma towards their love one related to depression, and experienced declines in their own well-being. Caregivers' personal and external resources helped with caregiving role and additional resources are needed from the healthcare system. Conclusion: There is an immediate need for increased healthcare resources for older adults with depression and their family members. This study provides insight for clinicians and policy makers to implement resources to optimize the caregiving role.
Advisors/Committee Members: Cameron, Jill I, Rehabilitation Science.
Subjects/Keywords: Caregiver; Depression; Family; Qualitative; Seniors; 0347
Wang, C. (2019). Understanding Experiences and Support Needs of Families Caring for Older Adults with Depression . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/99897
Wang, Chen. "Understanding Experiences and Support Needs of Families Caring for Older Adults with Depression." 2019. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/99897.
Wang, Chen. "Understanding Experiences and Support Needs of Families Caring for Older Adults with Depression." 2019. Web. 17 Jan 2021.
Wang C. Understanding Experiences and Support Needs of Families Caring for Older Adults with Depression. [Internet] [Masters thesis]. University of Toronto; 2019. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/99897.
Wang C. Understanding Experiences and Support Needs of Families Caring for Older Adults with Depression. [Masters Thesis]. University of Toronto; 2019. Available from: http://hdl.handle.net/1807/99897
25. Lustig, Jason Andrew. The PREVENT Study: Psychiatric Reporting to Ease Vehicular Events Near Traffic.
This thesis analyses health services data for a group of 23,145 patients who were warned by their physicians regarding motor vehicle driving risks between April… (more)
This thesis analyses health services data for a group of 23,145 patients who were warned by their physicians regarding motor vehicle driving risks between April 1, 2006 and March 31, 2011. A three-year baseline interval prior to the warning was compared to the one year subsequent to the warning for the rate of involvement in motor vehicle crashes and for psychiatric hospitalization. The relative risk of involvement in a serious crash in the subsequent compared to the baseline interval was 0.69 (95% confidence interval 0.59 to 0.81, P
Advisors/Committee Members: Redelmeier, A Donald, Health Policy, Management and Evaluation.
Subjects/Keywords: Mental Health; Motor Vehicle Crashes; Traffic Safety; 0347
Lustig, J. A. (2014). The PREVENT Study: Psychiatric Reporting to Ease Vehicular Events Near Traffic . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/67983
Lustig, Jason Andrew. "The PREVENT Study: Psychiatric Reporting to Ease Vehicular Events Near Traffic." 2014. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/67983.
Lustig, Jason Andrew. "The PREVENT Study: Psychiatric Reporting to Ease Vehicular Events Near Traffic." 2014. Web. 17 Jan 2021.
Lustig JA. The PREVENT Study: Psychiatric Reporting to Ease Vehicular Events Near Traffic. [Internet] [Masters thesis]. University of Toronto; 2014. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/67983.
Lustig JA. The PREVENT Study: Psychiatric Reporting to Ease Vehicular Events Near Traffic. [Masters Thesis]. University of Toronto; 2014. Available from: http://hdl.handle.net/1807/67983
26. Brown, C. Nicole. Oxidative Stress in Bipolar Disorder: a Meta-analysis of Oxidative Stress Markers and an Investigation of the Hippocampus.
Bipolar disorder is a prevalent and debilitating disease, however, its pathophysiology remains unknown. There is substantial evidence of oxidative damage in bipolar disorder from both… (more)
Bipolar disorder is a prevalent and debilitating disease, however, its pathophysiology remains unknown. There is substantial evidence of oxidative damage in bipolar disorder from both peripheral and post-mortem samples, especially in the prefrontal cortex. It is the objective of this study to consolidate research measuring oxidative stress biomarkers in bipolar disorder through a meta-analysis and to determine if the hippocampus region is a specific target of oxidative damage through a biochemical study using post-mortem samples. Results from this study further confirm the presence of oxidative damage in bipolar disorder, but suggest that the hippocampus is not a target. We have also shown a global increase of 5-hydroxymethylcytosine in the hippocampus of patients with schizophrenia, suggesting a possible alteration in the demethylation pathway. Determining the exact targets of oxidative stress in bipolar disorder may lead to biomarker development, better treatment and diagnostic options, and ultimately, a better quality of life for patients.
Advisors/Committee Members: Young, L. Trevor, Pharmacology.
Subjects/Keywords: 5-hydroxymethylcytosine; Bipolar disorder; Hippocampus; Lipid peroxidation; Oxidative stress; Schizophrenia; 0347
Brown, C. N. (2014). Oxidative Stress in Bipolar Disorder: a Meta-analysis of Oxidative Stress Markers and an Investigation of the Hippocampus . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/68485
Brown, C Nicole. "Oxidative Stress in Bipolar Disorder: a Meta-analysis of Oxidative Stress Markers and an Investigation of the Hippocampus." 2014. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/68485.
Brown, C Nicole. "Oxidative Stress in Bipolar Disorder: a Meta-analysis of Oxidative Stress Markers and an Investigation of the Hippocampus." 2014. Web. 17 Jan 2021.
Brown CN. Oxidative Stress in Bipolar Disorder: a Meta-analysis of Oxidative Stress Markers and an Investigation of the Hippocampus. [Internet] [Masters thesis]. University of Toronto; 2014. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/68485.
Brown CN. Oxidative Stress in Bipolar Disorder: a Meta-analysis of Oxidative Stress Markers and an Investigation of the Hippocampus. [Masters Thesis]. University of Toronto; 2014. Available from: http://hdl.handle.net/1807/68485
27. Patel, Hiren. Examining Cardiorespiratory Fitness in Diabetic Individuals with and without Psychotic Illness.
Aim: To measure cardiorespiratory fitness (CRF) in diabetic individuals with and without a psychotic illness and healthy controls and determine whether the presence of psychosis… (more)
Aim: To measure cardiorespiratory fitness (CRF) in diabetic individuals with and without a psychotic illness and healthy controls and determine whether the presence of psychosis increases the risk of cardiovascular disease in Type 2 Diabetes Mellitus (T2DM).Methods: CRF was assessed using the six minute walk test (6MWT) and self reported questionnaires assessed physical activity, quality of life and perceived exertion. Results: Individuals with T2DM and a comorbid psychotic illness had a significantly lower CRF when compared to people with T2DM alone. CRF in both T2DM groups was significantly lower compared to previously-collected data on healthy Canadians. Conclusion: CRF is reduced in T2DM and the co-occurrence of psychotic illness reduces fitness further. More attention needs to be directed at improving CRF in this population, in both primary care and psychiatric settings. Success in improving fitness in this vulnerable population may reduce medical comorbidity, improve quality of life, and prolong lifespan.
Advisors/Committee Members: Ganguli, Rohan, Medical Science.
Subjects/Keywords: 6 Minute Walk Test; Cardiorespiratory Fitness; Psychosis; Type 2 Diabetes; 0347
Patel, H. (2014). Examining Cardiorespiratory Fitness in Diabetic Individuals with and without Psychotic Illness . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/68506
Patel, Hiren. "Examining Cardiorespiratory Fitness in Diabetic Individuals with and without Psychotic Illness." 2014. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/68506.
Patel, Hiren. "Examining Cardiorespiratory Fitness in Diabetic Individuals with and without Psychotic Illness." 2014. Web. 17 Jan 2021.
Patel H. Examining Cardiorespiratory Fitness in Diabetic Individuals with and without Psychotic Illness. [Internet] [Masters thesis]. University of Toronto; 2014. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/68506.
Patel H. Examining Cardiorespiratory Fitness in Diabetic Individuals with and without Psychotic Illness. [Masters Thesis]. University of Toronto; 2014. Available from: http://hdl.handle.net/1807/68506
28. Sit, Victoria. Sexual Assault and Formal Service Use: Understanding Help-seeking among Women Living in Poverty.
Despite the extensive and often long-lasting sequelae of sexual assault, a significant majority of survivors do not seek assistance from formal support sources. While past… (more)
Despite the extensive and often long-lasting sequelae of sexual assault, a significant majority of survivors do not seek assistance from formal support sources. While past research has identified factors that influence help-seeking among survivors, limited attention has been paid to the role of socioeconomic status in shaping these decisions. Guided by Liang and colleagues' (2005) three-stage help-seeking model, this qualitative study aims to develop an in-depth, contextualized understanding of the help-seeking processes of sexual assault survivors living in poverty, along with suggestions on how formal service use rates and experiences can be improved. Semi-structured interviews were conducted with fifteen women, and thematic analysis was applied to the data. Results reveal a number of barriers and illustrate the ways in which limited resources contribute to decisions to delay help-seeking, avoid certain support sources, or not seek help altogether. Drawing upon participants' recommendations, implications for formal services and future research are discussed.
Advisors/Committee Members: Stermac, Lana, Applied Psychology and Human Development.
Subjects/Keywords: barriers; help-seeking; low-income; mental health; poverty; sexual assault; 0347
Sit, V. (2015). Sexual Assault and Formal Service Use: Understanding Help-seeking among Women Living in Poverty . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/69733
Sit, Victoria. "Sexual Assault and Formal Service Use: Understanding Help-seeking among Women Living in Poverty." 2015. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/69733.
Sit, Victoria. "Sexual Assault and Formal Service Use: Understanding Help-seeking among Women Living in Poverty." 2015. Web. 17 Jan 2021.
Sit V. Sexual Assault and Formal Service Use: Understanding Help-seeking among Women Living in Poverty. [Internet] [Masters thesis]. University of Toronto; 2015. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/69733.
Sit V. Sexual Assault and Formal Service Use: Understanding Help-seeking among Women Living in Poverty. [Masters Thesis]. University of Toronto; 2015. Available from: http://hdl.handle.net/1807/69733
29. Goodman, Michelle Samantha. Evaluating The Effects of Cannabis Dependence and Abstinence on Cortical Inhibition and Working Memory in Schizophrenia.
Background: Cannabis is the most commonly used illicit substance among schizophrenia patients. GABA is inhibited by cannabis and dysfunctional GABAergic neurotransmission underlies cognitive and cortical… (more)
Background: Cannabis is the most commonly used illicit substance among schizophrenia patients. GABA is inhibited by cannabis and dysfunctional GABAergic neurotransmission underlies cognitive and cortical inhibitory deficits in schizophrenia patients. This study investigated the relationship between cannabis dependence, schizophrenia, cortical inhibition and cognition. Methodology: Using transcranial magnetic stimulation and the N-back task with electroencephalography, we assessed cortical inhibition and working memory at baseline and following 28-days of abstinence in 12 cannabis dependent patients versus 14 cannabis dependent non-psychiatric controls. Results: Enhanced GABAB activity, through a prolonged cortical silent period, was found in patients compared to controls at baseline, with no differences following abstinence. No differences were found on working memory accuracy or gamma activity. Conclusions: While these findings suggest that cannabis dependence may have more impairing effects on GABAB mediated inhibition in controls compared to patients, it is clear that continued research is needed to better understand this common co-morbidity.
Advisors/Committee Members: George, Tony P, Medical Science.
Subjects/Keywords: Cannabis; Cortical Inhibition; EEG; Schizophrenia; Working Memory; 0347
Goodman, M. S. (2015). Evaluating The Effects of Cannabis Dependence and Abstinence on Cortical Inhibition and Working Memory in Schizophrenia . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/70338
Goodman, Michelle Samantha. "Evaluating The Effects of Cannabis Dependence and Abstinence on Cortical Inhibition and Working Memory in Schizophrenia." 2015. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/70338.
Goodman, Michelle Samantha. "Evaluating The Effects of Cannabis Dependence and Abstinence on Cortical Inhibition and Working Memory in Schizophrenia." 2015. Web. 17 Jan 2021.
Goodman MS. Evaluating The Effects of Cannabis Dependence and Abstinence on Cortical Inhibition and Working Memory in Schizophrenia. [Internet] [Masters thesis]. University of Toronto; 2015. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/70338.
Goodman MS. Evaluating The Effects of Cannabis Dependence and Abstinence on Cortical Inhibition and Working Memory in Schizophrenia. [Masters Thesis]. University of Toronto; 2015. Available from: http://hdl.handle.net/1807/70338
30. Cha, Danielle Soh-Young. A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial Evaluating the Effect of Intranasal Insulin on Cognition and Emotional Processing in Individuals with Treatment-Resistant Major Depressive Disorder.
Aim: Available evidence indicates that individuals with major depressive disorder (MDD) differentially respond to emotionally valenced information alongside impairments in cognition; however, the exact underlying… (more)
Aim: Available evidence indicates that individuals with major depressive disorder (MDD) differentially respond to emotionally valenced information alongside impairments in cognition; however, the exact underlying pathophysiological mechanisms subserving these deficits have yet to be elucidated. This thesis represents a proof-of-concept study informed by extant evidence implicating altered brain metabolism and function in individuals with MDD. Methods: Subjects (N=35) were randomized to receive 40 IU QID placebo (n=16) or insulin (n=19) in this double-blind, placebo-controlled, crossover study to examine the effects of intranasal insulin on measures evaluating mood, neurocognition, and quality of life. Results: No significant differences were observed on any primary measures of interest following analyses. However, methodological limitations (i.e., significant carryover/practice effects) should be taken into consideration for interpretation. Conclusion: Intranasal insulin did not demonstrate an effect on mood, neurocognitive/ neuropsychological, or quality of life metrics. Approaches for future trials with intranasal insulin in this clinical population are discussed.
Advisors/Committee Members: McIntyre, Dr. Roger S., Medical Science.
Subjects/Keywords: Cognition; Emotion; Intranasal Insulin; Major Depressive Disorder; Treatment Resistance; 0347
Cha, D. S. (2016). A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial Evaluating the Effect of Intranasal Insulin on Cognition and Emotional Processing in Individuals with Treatment-Resistant Major Depressive Disorder . (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/71672
Cha, Danielle Soh-Young. "A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial Evaluating the Effect of Intranasal Insulin on Cognition and Emotional Processing in Individuals with Treatment-Resistant Major Depressive Disorder." 2016. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/71672.
Cha, Danielle Soh-Young. "A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial Evaluating the Effect of Intranasal Insulin on Cognition and Emotional Processing in Individuals with Treatment-Resistant Major Depressive Disorder." 2016. Web. 17 Jan 2021.
Cha DS. A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial Evaluating the Effect of Intranasal Insulin on Cognition and Emotional Processing in Individuals with Treatment-Resistant Major Depressive Disorder. [Internet] [Masters thesis]. University of Toronto; 2016. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/71672.
Cha DS. A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial Evaluating the Effect of Intranasal Insulin on Cognition and Emotional Processing in Individuals with Treatment-Resistant Major Depressive Disorder. [Masters Thesis]. University of Toronto; 2016. Available from: http://hdl.handle.net/1807/71672