The American Journal of Drug and Alcohol Abuse
Drug or alcohol-induced neuroinflammation: insights from pre-clinical models and clinical research
Ricardo M Pautassi, INIMEC - CONICET- UNC (Argentina)
Terrence Deak, SUNY Binghamton (USA)
Anny Gano, SUNY Binghamton (USA)
Special Issue "Drug or alcohol-induced neuroinflammation: insights from pre-clinical models and clinical research"
Guest Editors, Drs. Terrence Deak and Anny Gano (Binghamton University-State University of New York, USA)
Senior Editor, Dr. Ricardo M Pautassi (National University of Córdoba, Argentina)
We invite authors to submit clinical and preclinical original research or reviews to a new special issue of The American Journal of Drug and Alcohol Abuse (AJDAA, 2020 Impact Factor: 3.829), "Drug or alcohol-induced neuroinflammation: insights from pre-clinical models and clinical research". Neuroinflammation involves the activation of the brain's innate immune system and is characterized by a host of adaptive responses, including mobilization and activation of microglia and other glial cells and the subsequent release of cytokines, chemokines, and other molecules. Inflammation-related signaling in the CNS fluctuates across cycles of drug use and misuse, and have been implicated in neural plasticity-like changes that portend the development of Substance Use Disorders (SUDs).
More in detail, this Special Issue seeks manuscript submissions broadly addressing the role of inflammatory-related processes in drug use and misuse. Submissions in the following areas are of particular interest:
Parametric studies that critically evaluate the role of age (perinatal, adolescent, adult, or aging-related), sex, and other environmental variables (conditioned responses) on neuroinflammatory processes provoked by psychoactive drugs;
Mechanistic studies on cellular, molecular, and behavioral mechanisms by which alcohol or other drugs influence neuroinflammatory processes, and how they pertain to addictive processes or its long-term health consequences;
Pharmacological studies targeting inflammatory-signaling pathways and their potential use as therapeutics in SUDs;
Genetic studies implicating inflammatory processes in the development and/or expression of SUDs;
Intersectional studies on poly drug use and potential additive/synergistic effects on neuroinflammatory processes; and,
Studies of SUDs and associated co-morbidities (e.g., anxiety, depression, etc.) that point toward neuroinflammatory processes as a common underlying mechanism.
These avenues of research are just examples of the richness and possibilities brought by the analysis of drug-induced -acute, chronic or conditioned- neuroinflammation. The role of traditional molecular (e.g., activation of innate immune receptors such the toll-like-receptor) or cellular underpinnings of neuroinflammation will be welcomed; as well as manuscripts assessing or reviewing pharmacological or environmental tools to ameliorate drug-induced neuroinflammation or its consequences.
Contact information: Questions on this special issue can be sent directly to the Senior Editor, Dr. Ricardo M Pautassi at: [email protected] or [email protected]
Types of articles to be included: The American Journal of Drug and Alcohol Abuse accepts the following types of articles: Perspectives, Reviews, Original Articles, Letters to the Editor, and Methods in Addiction Research. Contributions across all types of articles received by the journal will be considered for this Special Issue.
Submission process: Authors may submit an abstract to the Senior Editor to assess thematic suitability of the contribution for the Special Issue. This is not a requirement.
Manuscripts should be sent via this journal's ScholarOne manuscript submission system at https://mc.manuscriptcentral.com/lada. When asked if your submission is to be included in a special issue, please select the "Drug or alcohol-induced neuroinflammation: insights from pre-clinical models and clinical research". If you haven't submitted a paper to this journal before, you will need to create an account in ScholarOne. Please read author's guidelines at https://www.tandfonline.com/action/authorSubmission?show=instructions&journalCode=iada20#submitting-your-paper