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What is the state capitol of Nevada?
The state capitol of Nevada is Carson City which was founded in 1858 and is named after Kit Carson.
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### Instruction: What is the state capitol of Nevada? ### Context: ### Answer: The state capitol of Nevada is Carson City which was founded in 1858 and is named after Kit Carson.</s>
How should I make a good pizza tonight?
Make a delicious pizza by starting with the ingredients. First, gather flour, water, yeast and salt. Combine these ingredients and let the dough rise. Roll the dough into a circle. Next, gather tomatoes and crush them with a hint of salt and olive oil. Spread this mixture on top of the dough. Cover the mixture with heaps of cheese and fresh basil. Drizzle the pizza with olive oil. Then put the pizza in a very hot oven and let it cook for 6 minutes. Finally, eat your delicious pizza.
open_qa
### Instruction: How should I make a good pizza tonight? ### Context: ### Answer: Make a delicious pizza by starting with the ingredients. First, gather flour, water, yeast and salt. Combine these ingredients and let the dough rise. Roll the dough into a circle. Next, gather tomatoes and crush them with a hint of salt and olive oil. Spread this mixture on top of the dough. Cover the mixture with heaps of cheese and fresh basil. Drizzle the pizza with olive oil. Then put the pizza in a very hot oven and let it cook for 6 minutes. Finally, eat your delicious pizza.</s>
In what month did the Russian October revolution take place
November
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### Instruction: In what month did the Russian October revolution take place ### Context: ### Answer: November</s>
Name the members of the band Phish
The band Phish started in Vermont in the 1980s. The current members of the band are Trey Anastasio, Mike Gordon, Jon Fishman, and Page McConnell. Jeff Holdsworth is a past member of the band. Others (Tom Marshall and Marc Daubert) have contributed to the band's songwriting but not as members of the band.
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### Instruction: Name the members of the band Phish ### Context: ### Answer: The band Phish started in Vermont in the 1980s. The current members of the band are Trey Anastasio, Mike Gordon, Jon Fishman, and Page McConnell. Jeff Holdsworth is a past member of the band. Others (Tom Marshall and Marc Daubert) have contributed to the band's songwriting but not as members of the band.</s>
What is the currency in use in the Netherlands?
The currency in use in the Netherlands is the euro.
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### Instruction: What is the currency in use in the Netherlands? ### Context: ### Answer: The currency in use in the Netherlands is the euro.</s>
How to make an americano ?
The classical Americano needs a specific ratio between coffee and water: 2 parts of water and 1 part of expresso. Ideally, you can use coffee beans and grind them just before you brew. With a coffee machine: make one shot of expresso in a mug and fill it to the top with additional hot water at 60 degrees Celsius.
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### Instruction: How to make an americano ? ### Context: ### Answer: The classical Americano needs a specific ratio between coffee and water: 2 parts of water and 1 part of expresso. Ideally, you can use coffee beans and grind them just before you brew. With a coffee machine: make one shot of expresso in a mug and fill it to the top with additional hot water at 60 degrees Celsius.</s>
What are Flos
Flos is a genus of butterflies in the family Lycaenidae. The species of this genus are commonly known as plushblues and are found in the Indomalayan realm.
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### Instruction: What are Flos ### Context: ### Answer: Flos is a genus of butterflies in the family Lycaenidae. The species of this genus are commonly known as plushblues and are found in the Indomalayan realm.</s>
What is the difference between Eczema and Atopic Dermatitis?
Eczema is a general term for chronic conditions of skin inflammation whereas Atopic Dermatitis is a specific type of Eczema.
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### Instruction: What is the difference between Eczema and Atopic Dermatitis? ### Context: ### Answer: Eczema is a general term for chronic conditions of skin inflammation whereas Atopic Dermatitis is a specific type of Eczema.</s>
Who is Mauricio Macri?
Mauricio Macri, born 8 February 1959, is an Argentine businessman and politician who served as the President of Argentina from 2015 to 2019. He has been the leader of the Republican Proposal (PRO) party since its founding in 2005. He previously served as 5th Chief of Government of Buenos Aires from 2007 to 2015, and was a member of the Chamber of Deputies representing Buenos Aires from 2005 to 2007. Ideologically, he identifies himself as a liberal and conservative on the Argentine centre-right.
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### Instruction: Who is Mauricio Macri? ### Context: ### Answer: Mauricio Macri, born 8 February 1959, is an Argentine businessman and politician who served as the President of Argentina from 2015 to 2019. He has been the leader of the Republican Proposal (PRO) party since its founding in 2005. He previously served as 5th Chief of Government of Buenos Aires from 2007 to 2015, and was a member of the Chamber of Deputies representing Buenos Aires from 2005 to 2007. Ideologically, he identifies himself as a liberal and conservative on the Argentine centre-right.</s>
Who is John Schneider
John Schneider is an actor, theatre director, playwright, and musician based in Milwaukee, Wisconsin. He is currently the Arts and Entertainment Editor for the Shepherd Express and a theatre arts professor at Marquette University.
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### Instruction: Who is John Schneider ### Context: ### Answer: John Schneider is an actor, theatre director, playwright, and musician based in Milwaukee, Wisconsin. He is currently the Arts and Entertainment Editor for the Shepherd Express and a theatre arts professor at Marquette University.</s>
What causes global warming?
Global warming is caused by the release of greenhouses gases into the atmosphere. Greenhouse gases in the atmosphere trap the heat from the sun and lead to an overall increase in temperature on the planet. Greenhouse gases are mostly produced by burning fossil fuels like coal, oil, and natural gas. Deforestation is also a contributing factor to global warming since trees capture carbon from the atmosphere when growing, so cutting them down or burning them both releases carbon they’ve been storing, as well as removes their ability to clean the air.
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### Instruction: What causes global warming? ### Context: ### Answer: Global warming is caused by the release of greenhouses gases into the atmosphere. Greenhouse gases in the atmosphere trap the heat from the sun and lead to an overall increase in temperature on the planet. Greenhouse gases are mostly produced by burning fossil fuels like coal, oil, and natural gas. Deforestation is also a contributing factor to global warming since trees capture carbon from the atmosphere when growing, so cutting them down or burning them both releases carbon they’ve been storing, as well as removes their ability to clean the air.</s>
What are the classical states of matter?
1. Solid: Matter in a solid state is comprised of particles that are held very closely together. Solids hold a definite shape. 2. Liquid: Matter is in a mostly non-compressible fluid state. Liquid matter conforms to the shape of its container. 3. Gas: Matter in a gaseous state is composed of compressible fluids. It may also take the shape of its container, but it will also expand to fill the container.
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### Instruction: What are the classical states of matter? ### Context: ### Answer: 1. Solid: Matter in a solid state is comprised of particles that are held very closely together. Solids hold a definite shape. 2. Liquid: Matter is in a mostly non-compressible fluid state. Liquid matter conforms to the shape of its container. 3. Gas: Matter in a gaseous state is composed of compressible fluids. It may also take the shape of its container, but it will also expand to fill the container.</s>
What is a synapse notebook?
A synapse notebook is a technology built by Microsoft that takes advantage of spark pools. This is an environment that Data Scientists, Machine Learning Engineers, and Data Engineers can work in to build models, data engineering workflows, and neural networks to name a few. It is very similar to Jupyter notebook style. These notebooks environments enable code to be written in a modular format in different cells which can be executed independently of one another.
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### Instruction: What is a synapse notebook? ### Context: ### Answer: A synapse notebook is a technology built by Microsoft that takes advantage of spark pools. This is an environment that Data Scientists, Machine Learning Engineers, and Data Engineers can work in to build models, data engineering workflows, and neural networks to name a few. It is very similar to Jupyter notebook style. These notebooks environments enable code to be written in a modular format in different cells which can be executed independently of one another.</s>
Abel Prize is given in which field ?
Abel Prize is given in the field of Mathematics
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### Instruction: Abel Prize is given in which field ? ### Context: ### Answer: Abel Prize is given in the field of Mathematics</s>
Who started the Reformation?
The reformation was started by Martin Luther
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### Instruction: Who started the Reformation? ### Context: ### Answer: The reformation was started by Martin Luther</s>
Name some of the bravolebrities from Vanderpump Rules
James Kennedy, Katie Maloney, Raquel Leviss, Tom Sandoval, Ariana Madix, Tom Schwartz and Lala Kent
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### Instruction: Name some of the bravolebrities from Vanderpump Rules ### Context: ### Answer: James Kennedy, Katie Maloney, Raquel Leviss, Tom Sandoval, Ariana Madix, Tom Schwartz and Lala Kent</s>
Why is it a good idea to walk every day?
Walking is a good exercise for burning calories without causing any damage to joints. People of any age can do it and a few miles a day can result in positive effects on cardiovascular health and general fitness.
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### Instruction: Why is it a good idea to walk every day? ### Context: ### Answer: Walking is a good exercise for burning calories without causing any damage to joints. People of any age can do it and a few miles a day can result in positive effects on cardiovascular health and general fitness.</s>
What is a crypto (cryptocurrency)?
A cryptocurrency, crypto-currency, or crypto is a digital currency designed to work as a medium of exchange through a computer network that is not reliant on any central authority, such as a government or bank, to uphold or maintain it. It is a decentralized system for verifying that the parties to a transaction have the money they claim to have, eliminating the need for traditional intermediaries, such as banks, when funds are being transferred between two entities.
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### Instruction: What is a crypto (cryptocurrency)? ### Context: ### Answer: A cryptocurrency, crypto-currency, or crypto is a digital currency designed to work as a medium of exchange through a computer network that is not reliant on any central authority, such as a government or bank, to uphold or maintain it. It is a decentralized system for verifying that the parties to a transaction have the money they claim to have, eliminating the need for traditional intermediaries, such as banks, when funds are being transferred between two entities.</s>
in which city was the first public opera house opened
Venice
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### Instruction: in which city was the first public opera house opened ### Context: ### Answer: Venice</s>
Name the main crochet stitches
The main crochet stitches include the single crochet stitch, the double crochet stitch, the half double crochet stitch, the treble stitch and the slip stitch
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### Instruction: Name the main crochet stitches ### Context: ### Answer: The main crochet stitches include the single crochet stitch, the double crochet stitch, the half double crochet stitch, the treble stitch and the slip stitch</s>
What is the name of the curvy street in San Francisco?
Lombard Street in San Francisco is often referred to as the "crookedest" or most curvy street in the world.
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### Instruction: What is the name of the curvy street in San Francisco? ### Context: ### Answer: Lombard Street in San Francisco is often referred to as the "crookedest" or most curvy street in the world.</s>
What does a geologist do?
A geologist studies rocks that come from the earth. They evaluate the composition of rocks in order to determine how long ago layers in rock formations were formed. They are able to give us a clear objective history of how the earth was formed and how it has adapted over time.
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### Instruction: What does a geologist do? ### Context: ### Answer: A geologist studies rocks that come from the earth. They evaluate the composition of rocks in order to determine how long ago layers in rock formations were formed. They are able to give us a clear objective history of how the earth was formed and how it has adapted over time.</s>
What position is best to use in your Fantasy Football flex slot?
The majority of fantasy football players believe it is best to use a running-back in your flex spot because running-backs traditionally receive the ball (touches) more often than wider receivers or tight-ends. More touches theoretically means more opportunities to score points. However, with recent NFL rule changes, stronger and faster wide receivers, and fantasy football scoring systems that provide extra points for catching a pass (catches) wide receivers are scoring significantly more points than running backs on a weekly basis. Therefore, it is advised to play a wider receiver in your fantasy football flex spot.
open_qa
### Instruction: What position is best to use in your Fantasy Football flex slot? ### Context: ### Answer: The majority of fantasy football players believe it is best to use a running-back in your flex spot because running-backs traditionally receive the ball (touches) more often than wider receivers or tight-ends. More touches theoretically means more opportunities to score points. However, with recent NFL rule changes, stronger and faster wide receivers, and fantasy football scoring systems that provide extra points for catching a pass (catches) wide receivers are scoring significantly more points than running backs on a weekly basis. Therefore, it is advised to play a wider receiver in your fantasy football flex spot.</s>
What are people from Wisconsin also referred to as?
Some people refer to people from Wisconsin as Cheeseheads because of the amount of dairy that is produced by the state. It was a derogatory term set in from a local sports rivalry with people from Illinois, however the Cheeseheads from Wisconsin embraced it, and now wear Cheesehead hats to local sporting events.
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### Instruction: What are people from Wisconsin also referred to as? ### Context: ### Answer: Some people refer to people from Wisconsin as Cheeseheads because of the amount of dairy that is produced by the state. It was a derogatory term set in from a local sports rivalry with people from Illinois, however the Cheeseheads from Wisconsin embraced it, and now wear Cheesehead hats to local sporting events.</s>
what are the most popular sports in america
The most popular sports in america are football, baseball, basketball, hockey
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### Instruction: what are the most popular sports in america ### Context: ### Answer: The most popular sports in america are football, baseball, basketball, hockey</s>
What are the typical ingredient for Italian tomato sauce
While there are so many variations of making Italian tomato sauce, the typical ingredients are chopped garlic and or onion, olive oil, tomato paste, tomato purée, diced tomatoes and or crushed tomatoes. You may use Basil and or oregano salt and pepper for seasoning. It is also traditional to add pre boiled pork neck bones, sausage, meatballs or other meats to the sauce. Sometimes other vegetables are added like mushrooms, green peppers etc. Many recipes exist. Buon Appetito!
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### Instruction: What are the typical ingredient for Italian tomato sauce ### Context: ### Answer: While there are so many variations of making Italian tomato sauce, the typical ingredients are chopped garlic and or onion, olive oil, tomato paste, tomato purée, diced tomatoes and or crushed tomatoes. You may use Basil and or oregano salt and pepper for seasoning. It is also traditional to add pre boiled pork neck bones, sausage, meatballs or other meats to the sauce. Sometimes other vegetables are added like mushrooms, green peppers etc. Many recipes exist. Buon Appetito!</s>
What is a "frunk" in an electric vehicle?
The frunk is the front trunk, which in an electric vehicle is typically used as additional storage space.
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### Instruction: What is a "frunk" in an electric vehicle? ### Context: ### Answer: The frunk is the front trunk, which in an electric vehicle is typically used as additional storage space.</s>
Name some of the bravolebrities from Below Deck
Captain Lee Rosbach, Chef Rachel Hargrove, Stew Fraser Olender and former Chief Stew Kate Chastain
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### Instruction: Name some of the bravolebrities from Below Deck ### Context: ### Answer: Captain Lee Rosbach, Chef Rachel Hargrove, Stew Fraser Olender and former Chief Stew Kate Chastain</s>
What are equity securities?
Equity securities are financial assets that represent ownership of a corporation. The most prevalent type of equity security is common stock. And the characteristic that most defines an equity security—differentiating it from most other types of securities—is ownership.
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### Instruction: What are equity securities? ### Context: ### Answer: Equity securities are financial assets that represent ownership of a corporation. The most prevalent type of equity security is common stock. And the characteristic that most defines an equity security—differentiating it from most other types of securities—is ownership.</s>
The Weeknd samples which '80s megahit in "Blinding Lights?"
"Take On Me" by A-ha
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### Instruction: The Weeknd samples which '80s megahit in "Blinding Lights?" ### Context: ### Answer: "Take On Me" by A-ha</s>
What is the company zoom?
Zoom is a video communication protocol used by many companies today. Zoom has been used by school to conduct at home schooling during the COVID-19 pandemic. Zoom is also used by big Fortune 500 corporations to conduct business meetings internally with employees and externally with customers and other accounts. The virtual interaction offered by zoom is a great alternative to save costs on in-person meetings where physical travel is required. The company was founded in 2011 and has about 8500 employees as of 2023.
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### Instruction: What is the company zoom? ### Context: ### Answer: Zoom is a video communication protocol used by many companies today. Zoom has been used by school to conduct at home schooling during the COVID-19 pandemic. Zoom is also used by big Fortune 500 corporations to conduct business meetings internally with employees and externally with customers and other accounts. The virtual interaction offered by zoom is a great alternative to save costs on in-person meetings where physical travel is required. The company was founded in 2011 and has about 8500 employees as of 2023.</s>
What was invented by Dr Albert Southwick in 1881
Electric chair
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### Instruction: What was invented by Dr Albert Southwick in 1881 ### Context: ### Answer: Electric chair</s>
What singer was born Georgios Kyriacos Panayiotou?
George Michael.
open_qa
### Instruction: What singer was born Georgios Kyriacos Panayiotou? ### Context: ### Answer: George Michael.</s>
Cases of Anthrax were found in Kerala in which animals?
Wild Boars
open_qa
### Instruction: Cases of Anthrax were found in Kerala in which animals? ### Context: ### Answer: Wild Boars</s>
What are the main ingredients for making bread?
Flour, water, yeast, and salt
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### Instruction: What are the main ingredients for making bread? ### Context: ### Answer: Flour, water, yeast, and salt</s>
Name a good sorting algorithm
Quicksort
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### Instruction: Name a good sorting algorithm ### Context: ### Answer: Quicksort</s>
What year did the hindenburg disaster occur?
The Hindenburg disaster occurred on May 6, 1937, when the Hindenburg airship caught fire and was destroyed during its attempt to dock with its mooring mast at Naval Air Station Lakehurst.
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### Instruction: What year did the hindenburg disaster occur? ### Context: ### Answer: The Hindenburg disaster occurred on May 6, 1937, when the Hindenburg airship caught fire and was destroyed during its attempt to dock with its mooring mast at Naval Air Station Lakehurst.</s>
What are the disadvantages of Linux?
The disadvantages of Linux include limited hardware support, a steep learning curve, lack of commercial support, and compatibility issues.
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### Instruction: What are the disadvantages of Linux? ### Context: ### Answer: The disadvantages of Linux include limited hardware support, a steep learning curve, lack of commercial support, and compatibility issues.</s>
What are the majors in men's professional golf?
The four major tournaments are The Masters, The PGA Championship, The Open Championship and the U.S. Open.
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### Instruction: What are the majors in men's professional golf? ### Context: ### Answer: The four major tournaments are The Masters, The PGA Championship, The Open Championship and the U.S. Open.</s>
How many canals are in Amsterdam?
There are a total of 14 canals in Amsterdam, including the Singel, Herengracht, Keizersgracht, and Prinsengracht canals.
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### Instruction: How many canals are in Amsterdam? ### Context: ### Answer: There are a total of 14 canals in Amsterdam, including the Singel, Herengracht, Keizersgracht, and Prinsengracht canals.</s>
2022 UEFA European Under 19 Championship qualification
The 2022 UEFA European Under-19 Championship qualifying competition was a men's under-19 football competition that determined the seven teams joining the automatically qualified hosts Slovakia in the 2022 UEFA European Under-19 Championship final tournament. Players born on or after 1 January 2003 were eligible to participate. Originally, the qualifying competition would use a new format with teams split into three different leagues with promotion and relegation, with the draw of the first round under the new format already held in December 2019. However, on 17 June 2020, UEFA announced that the introduction of the new format had been postponed to the next edition due to the COVID-19 pandemic, and qualification for this edition would use the previous format involving two rounds only. Apart from Slovakia, 53 of the remaining 54 UEFA member national teams entered the qualifying competition, where the original format consisted of a qualifying round that took place in autumn 2021, and an elite round that took place in spring 2022.
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### Instruction: 2022 UEFA European Under 19 Championship qualification ### Context: ### Answer: The 2022 UEFA European Under-19 Championship qualifying competition was a men's under-19 football competition that determined the seven teams joining the automatically qualified hosts Slovakia in the 2022 UEFA European Under-19 Championship final tournament. Players born on or after 1 January 2003 were eligible to participate. Originally, the qualifying competition would use a new format with teams split into three different leagues with promotion and relegation, with the draw of the first round under the new format already held in December 2019. However, on 17 June 2020, UEFA announced that the introduction of the new format had been postponed to the next edition due to the COVID-19 pandemic, and qualification for this edition would use the previous format involving two rounds only. Apart from Slovakia, 53 of the remaining 54 UEFA member national teams entered the qualifying competition, where the original format consisted of a qualifying round that took place in autumn 2021, and an elite round that took place in spring 2022.</s>
The final of Asia cup was held in UAE, was won by Sri Lanka from which country
Pakistan by 23 runs
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### Instruction: The final of Asia cup was held in UAE, was won by Sri Lanka from which country ### Context: ### Answer: Pakistan by 23 runs</s>
What is the difference between an adverb and adjective?
An adjective describes an item, whereas an adverb modifies a verb
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### Instruction: What is the difference between an adverb and adjective? ### Context: ### Answer: An adjective describes an item, whereas an adverb modifies a verb</s>
What is a credit score?
A credit score is a numerical representation of a person's ability to buy using credit and paying off the credit spent. How much debt and how many credit cards a person has plays a factor in this numerical value. This value also represents the person's credit worthiness and information from credit bureaus helps to calculate the credit score. Credit scores are important when trying to get loans for things like cars, homes, and other things a person buys using financing.
open_qa
### Instruction: What is a credit score? ### Context: ### Answer: A credit score is a numerical representation of a person's ability to buy using credit and paying off the credit spent. How much debt and how many credit cards a person has plays a factor in this numerical value. This value also represents the person's credit worthiness and information from credit bureaus helps to calculate the credit score. Credit scores are important when trying to get loans for things like cars, homes, and other things a person buys using financing.</s>
What were the last ten states to enter the union of the United States?
In order of admission: Montana, Washington, Idaho, Wyoming, Utah, Oklahoma, New Mexico, Arizona, Alaska, and Hawaii.
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### Instruction: What were the last ten states to enter the union of the United States? ### Context: ### Answer: In order of admission: Montana, Washington, Idaho, Wyoming, Utah, Oklahoma, New Mexico, Arizona, Alaska, and Hawaii.</s>
What is the difference between the words ‘this’ and ‘that’?
The difference between ‘this’ and ‘that’ has to do with proximity. When referring to something that is in close proximity you would use the word ‘this’: “This finger hurts me the most.” Conversely, if something far away you would use the word that: “That hill off in the distance is called the Blue Hills.”
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### Instruction: What is the difference between the words ‘this’ and ‘that’? ### Context: ### Answer: The difference between ‘this’ and ‘that’ has to do with proximity. When referring to something that is in close proximity you would use the word ‘this’: “This finger hurts me the most.” Conversely, if something far away you would use the word that: “That hill off in the distance is called the Blue Hills.”</s>
What is Gingham fabric?
Gingham, also called Vichy check, is a medium-weight balanced plain-woven fabric typically with striped, check or plaid duotone patterns, in bright colour and in white made from dyed cotton or cotton-blend yarns. It is made of carded, medium or fine yarns.
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### Instruction: What is Gingham fabric? ### Context: ### Answer: Gingham, also called Vichy check, is a medium-weight balanced plain-woven fabric typically with striped, check or plaid duotone patterns, in bright colour and in white made from dyed cotton or cotton-blend yarns. It is made of carded, medium or fine yarns.</s>
do successful companies become public?
yes
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### Instruction: do successful companies become public? ### Context: ### Answer: yes</s>
What is Puha, New Zealand
Puha or Puhatikotiko is a locality between the Waipaoa River and the Waikohu River in the Gisborne District of New Zealand's North Island. It is located close to the confluence of the two rivers on State Highway 2 close to Te Karaka, inland from the city of Gisborne. A notable resident was Te Kani Te Ua.
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### Instruction: What is Puha, New Zealand ### Context: ### Answer: Puha or Puhatikotiko is a locality between the Waipaoa River and the Waikohu River in the Gisborne District of New Zealand's North Island. It is located close to the confluence of the two rivers on State Highway 2 close to Te Karaka, inland from the city of Gisborne. A notable resident was Te Kani Te Ua.</s>
What type of jacket do grizzlies usually wear?
Grizzlies are bears typically found in North America. Bears are animals that are covered in fur and usually live in the woods. Because they are covered in fur and live in the woods, it is unnecessary for bears to wear jackets. To date, bears have not shown the capacity to be able to create cloth or sew jackets, so they would have to get them from humans. Humans are usually afraid of bears and are not likely to approach a bear with a jacket. Therefore bears usually do not wear jackets.
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### Instruction: What type of jacket do grizzlies usually wear? ### Context: ### Answer: Grizzlies are bears typically found in North America. Bears are animals that are covered in fur and usually live in the woods. Because they are covered in fur and live in the woods, it is unnecessary for bears to wear jackets. To date, bears have not shown the capacity to be able to create cloth or sew jackets, so they would have to get them from humans. Humans are usually afraid of bears and are not likely to approach a bear with a jacket. Therefore bears usually do not wear jackets.</s>
What is the most popular sport in Brazil?
Football is the most popular sport in Brazil. It is a widespread sport practiced in schools, streets and clubs by millions of people. It is considered a national passion in the country.
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### Instruction: What is the most popular sport in Brazil? ### Context: ### Answer: Football is the most popular sport in Brazil. It is a widespread sport practiced in schools, streets and clubs by millions of people. It is considered a national passion in the country.</s>
How many albums has Taylor Swift released?
10 albums.
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### Instruction: How many albums has Taylor Swift released? ### Context: ### Answer: 10 albums.</s>
What are a few words that can be used to describe running?
You can use words like jog, fast, slow, trot, sprint, race, hurry, skip, dash, fly rush, to describe or replace run.
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### Instruction: What are a few words that can be used to describe running? ### Context: ### Answer: You can use words like jog, fast, slow, trot, sprint, race, hurry, skip, dash, fly rush, to describe or replace run.</s>
What is the oldest civilization in the world?
The oldest civilization in the world is the Mesopotamia civilization which lasted between 4000 - 3500 BC
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### Instruction: What is the oldest civilization in the world? ### Context: ### Answer: The oldest civilization in the world is the Mesopotamia civilization which lasted between 4000 - 3500 BC</s>
What is the tallest mountain in Colorado?
Mount Elbert is the tallest mountain in Colorado standing at 14,439 feet
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### Instruction: What is the tallest mountain in Colorado? ### Context: ### Answer: Mount Elbert is the tallest mountain in Colorado standing at 14,439 feet</s>
Which months were added to the calendar and why?
In order for the Roman calendar year which was ten months long, to be in sync with the lunar year, the months of January and February were added.
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### Instruction: Which months were added to the calendar and why? ### Context: ### Answer: In order for the Roman calendar year which was ten months long, to be in sync with the lunar year, the months of January and February were added.</s>
Explain the black and white smoke during the Pope election
Beginning in the early 1800s, the ballots used by cardinals were burned after each ballot to indicate a failed election. The lack of smoke instead signalled a successful election. Since 1914, black smoke (fumata nera) emerging from a temporary chimney installed on the roof of the Sistine Chapel indicates that the ballot did not result in an election, while white smoke (fumata bianca) announces that a new pope has been chosen. Prior to 1945 (when Pius XII changed the form of ballot to use unsigned ballots, first carried out in 1958), the sealing wax on the complex type ballots illustrated above had the effect of making the smoke from burning the ballots either black or white, depending on whether or not damp straw was added. Until the 20th century, sealing wax customarily had beeswax mixed into its composition. The use of wax made solely from animal fat does not give as much white colored smoke, as does wax that includes beeswax. In the 1939 conclave there was some confusion over the smoke color, which was even more apparent in the 1958 conclave. The lack of sealing wax on the ballots explains the confusion over the color of the smoke in the 1958 conclave. The Siri thesis was based on the confusion over the smoke color on the first day of that conclave. Since 1963, chemicals have been added to the burning process to augment the smoke's black or white color. Beginning in 2005, a successful election is also accentuated by bells ringing at the appearance of the white smoke. During the 2013 conclave, the Vatican disclosed the chemicals used to color the smoke—the black smoke comprises potassium perchlorate, anthracene, and sulfur; the white smoke is composed of potassium chlorate, lactose, and pine rosin.
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### Instruction: Explain the black and white smoke during the Pope election ### Context: ### Answer: Beginning in the early 1800s, the ballots used by cardinals were burned after each ballot to indicate a failed election. The lack of smoke instead signalled a successful election. Since 1914, black smoke (fumata nera) emerging from a temporary chimney installed on the roof of the Sistine Chapel indicates that the ballot did not result in an election, while white smoke (fumata bianca) announces that a new pope has been chosen. Prior to 1945 (when Pius XII changed the form of ballot to use unsigned ballots, first carried out in 1958), the sealing wax on the complex type ballots illustrated above had the effect of making the smoke from burning the ballots either black or white, depending on whether or not damp straw was added. Until the 20th century, sealing wax customarily had beeswax mixed into its composition. The use of wax made solely from animal fat does not give as much white colored smoke, as does wax that includes beeswax. In the 1939 conclave there was some confusion over the smoke color, which was even more apparent in the 1958 conclave. The lack of sealing wax on the ballots explains the confusion over the color of the smoke in the 1958 conclave. The Siri thesis was based on the confusion over the smoke color on the first day of that conclave. Since 1963, chemicals have been added to the burning process to augment the smoke's black or white color. Beginning in 2005, a successful election is also accentuated by bells ringing at the appearance of the white smoke. During the 2013 conclave, the Vatican disclosed the chemicals used to color the smoke—the black smoke comprises potassium perchlorate, anthracene, and sulfur; the white smoke is composed of potassium chlorate, lactose, and pine rosin.</s>
Name some famous rock bands from the San Francisco Bay Area.
Many famous rock bands have come from the San Francisco Bay area. These bands include the Grateful Dead, Journey, The Jefferson Airplane, Metallica, Santana, and Green Day.
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### Instruction: Name some famous rock bands from the San Francisco Bay Area. ### Context: ### Answer: Many famous rock bands have come from the San Francisco Bay area. These bands include the Grateful Dead, Journey, The Jefferson Airplane, Metallica, Santana, and Green Day.</s>
What are AAC devices used for?
AAC stands for Augmentative and Alternative Communication. AAC devices provide a way of communication for those with speech impairments. They can be used by people of all ages. There are various kind of AAC devices such as symbol cards or high tech mobile apps.
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### Instruction: What are AAC devices used for? ### Context: ### Answer: AAC stands for Augmentative and Alternative Communication. AAC devices provide a way of communication for those with speech impairments. They can be used by people of all ages. There are various kind of AAC devices such as symbol cards or high tech mobile apps.</s>
What is a protractor?
A protractor is a mathematical instrument/device that can be used to help calculate the angle
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### Instruction: What is a protractor? ### Context: ### Answer: A protractor is a mathematical instrument/device that can be used to help calculate the angle</s>
What caused the millenium tower to sink in san francisco?
The critics blame the city for allowing Millennium partners to anchor the building into packed sand rather than bedrock. The problem with Millennium tower arose because the 60 to 90-foot-long friction piles supporting it were driven into sandy soil rather than the bedrock, 200 feet down.
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### Instruction: What caused the millenium tower to sink in san francisco? ### Context: ### Answer: The critics blame the city for allowing Millennium partners to anchor the building into packed sand rather than bedrock. The problem with Millennium tower arose because the 60 to 90-foot-long friction piles supporting it were driven into sandy soil rather than the bedrock, 200 feet down.</s>
What is Hadoop?
The Apache Hadoop software library is a framework that allows for the distributed processing of large data sets across clusters of computers using simple programming models. It is designed to scale up from single servers to thousands of machines, each offering local computation and storage.
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### Instruction: What is Hadoop? ### Context: ### Answer: The Apache Hadoop software library is a framework that allows for the distributed processing of large data sets across clusters of computers using simple programming models. It is designed to scale up from single servers to thousands of machines, each offering local computation and storage.</s>
How did the United States win the Cold War?
A number of factors contributed to the United States defeating the Union of Soviet Socialist Republics (USSR) in the Cold War and becoming the world's most powerful state. A common view is that the U.S. won the Cold War because its capitalist economic system, characterized by free markets and the recognition of private property rights, was able to outperform the USSR's centrally-planned economy. The United States could therefore afford to spend more on its military than the USSR and won the nuclear arms race, which contributed to the internal collapse of the Soviet economy and the subsequent breakup of the Soviet Union into smaller, individual states with democratic elections. Additionally, though the USSR and the United States never officially engaged in direct military conflict with one another during the Cold War, various factions supported by the United States and its Western allies were able to successfully defeat Soviet-backed factions in proxy wars that took place all across the globe (with the notable exception of Vietnam). These defeats gradually limited the USSR's ability to project its power on the world stage, and helped the United States build and strengthen key alliances, including the North Atlantic Treaty Organization. Finally, the United States carried out effective intelligence, counter-intelligence, disinformation and propaganda campaigns that undermined the faith the USSR's population had in its government and buttressed support for the U.S. government's efforts domestically. By 1991, the Soviet Union had fallen and the U.S. had achieved global hegemony.
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### Instruction: How did the United States win the Cold War? ### Context: ### Answer: A number of factors contributed to the United States defeating the Union of Soviet Socialist Republics (USSR) in the Cold War and becoming the world's most powerful state. A common view is that the U.S. won the Cold War because its capitalist economic system, characterized by free markets and the recognition of private property rights, was able to outperform the USSR's centrally-planned economy. The United States could therefore afford to spend more on its military than the USSR and won the nuclear arms race, which contributed to the internal collapse of the Soviet economy and the subsequent breakup of the Soviet Union into smaller, individual states with democratic elections. Additionally, though the USSR and the United States never officially engaged in direct military conflict with one another during the Cold War, various factions supported by the United States and its Western allies were able to successfully defeat Soviet-backed factions in proxy wars that took place all across the globe (with the notable exception of Vietnam). These defeats gradually limited the USSR's ability to project its power on the world stage, and helped the United States build and strengthen key alliances, including the North Atlantic Treaty Organization. Finally, the United States carried out effective intelligence, counter-intelligence, disinformation and propaganda campaigns that undermined the faith the USSR's population had in its government and buttressed support for the U.S. government's efforts domestically. By 1991, the Soviet Union had fallen and the U.S. had achieved global hegemony.</s>
Define unemployment and how it is expressed in most countries.
Percentage of total workforce who are unemployed and are actively seeking a paid job. Unemployment rate (# of unemployed / # in labor force) = % Unemployment rate is one of the most closely watched statistics because a rising rate is seen as a sign of weakening economy that may call for cut in interest rate. A falling rate, similarly, indicates a growing economy which is usually accompanied by higher inflation rate and may call for increase in interest rates.
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### Instruction: Define unemployment and how it is expressed in most countries. ### Context: ### Answer: Percentage of total workforce who are unemployed and are actively seeking a paid job. Unemployment rate (# of unemployed / # in labor force) = % Unemployment rate is one of the most closely watched statistics because a rising rate is seen as a sign of weakening economy that may call for cut in interest rate. A falling rate, similarly, indicates a growing economy which is usually accompanied by higher inflation rate and may call for increase in interest rates.</s>
What is a zamboni?
A zamboni is a machine that resurfaces ice rinks used for skating. They are used in recreational skating, professional skating, team skating, and even on olympic skating rinks. After the ice is resurfaced skating becomes easier and more safe because there is less risk for a trip hazard on the ice.
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### Instruction: What is a zamboni? ### Context: ### Answer: A zamboni is a machine that resurfaces ice rinks used for skating. They are used in recreational skating, professional skating, team skating, and even on olympic skating rinks. After the ice is resurfaced skating becomes easier and more safe because there is less risk for a trip hazard on the ice.</s>
Who was the last king of the Reach before Aegon's Conquest?
Mern IX Gardener was the last king of the Reach. When the last of the Gardener's lineage died, the house went extinct and the Reach was assigned to House Tyrell to rule.
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### Instruction: Who was the last king of the Reach before Aegon's Conquest? ### Context: ### Answer: Mern IX Gardener was the last king of the Reach. When the last of the Gardener's lineage died, the house went extinct and the Reach was assigned to House Tyrell to rule.</s>
is a career in enterprise software a good was to go?
yes
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### Instruction: is a career in enterprise software a good was to go? ### Context: ### Answer: yes</s>
Why have modern newspapers declined in the 21st century?
Modern newspapers have declined due to a loss of advertising revenue in the 21st century with the rise of digital media as a serious source of competition
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### Instruction: Why have modern newspapers declined in the 21st century? ### Context: ### Answer: Modern newspapers have declined due to a loss of advertising revenue in the 21st century with the rise of digital media as a serious source of competition</s>
What is Game of Thrones based on?
Game of Thrones is based on the books written by George R. R. Martin called a Song of Ice and Fire.
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### Instruction: What is Game of Thrones based on? ### Context: ### Answer: Game of Thrones is based on the books written by George R. R. Martin called a Song of Ice and Fire.</s>
Who and when was the compass invented?
Over 2000 years ago by the Chinese, by magnetizing needles made from iron, and placing them in water
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### Instruction: Who and when was the compass invented? ### Context: ### Answer: Over 2000 years ago by the Chinese, by magnetizing needles made from iron, and placing them in water</s>
is security a great career
yes
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### Instruction: is security a great career ### Context: ### Answer: yes</s>
Why is the 1980 gold medal match in hockey called the 'Miracle on Ice'?
The US Olympic hockey team was a heavy underdog against the Soviets in 1980, and their victory over the Soviets was a surprise to nearly everyone. As the game concluded, Al Michaels, the play-by-play announcer for the game, exclaimed "Do you believe in miracles? Yes!', and because many people around the world watched the game on television, the game became known as the 'Miracle on Ice'.
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### Instruction: Why is the 1980 gold medal match in hockey called the 'Miracle on Ice'? ### Context: ### Answer: The US Olympic hockey team was a heavy underdog against the Soviets in 1980, and their victory over the Soviets was a surprise to nearly everyone. As the game concluded, Al Michaels, the play-by-play announcer for the game, exclaimed "Do you believe in miracles? Yes!', and because many people around the world watched the game on television, the game became known as the 'Miracle on Ice'.</s>
What are the interests behind climate change denial?
Financial interest from industries opposed to the regulation of CO2 emissions. Migrating to low carbon technologies would require massive investments, making executives concerned about impacts on companies gross margin.
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### Instruction: What are the interests behind climate change denial? ### Context: ### Answer: Financial interest from industries opposed to the regulation of CO2 emissions. Migrating to low carbon technologies would require massive investments, making executives concerned about impacts on companies gross margin.</s>
What links Brazil, Uruguay, Mozambique and Angola
Colonies of Portugal
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### Instruction: What links Brazil, Uruguay, Mozambique and Angola ### Context: ### Answer: Colonies of Portugal</s>
Who is the primary male protagonist on the TV show "The X-Files"?
Special Agent Fox William Mulder
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### Instruction: Who is the primary male protagonist on the TV show "The X-Files"? ### Context: ### Answer: Special Agent Fox William Mulder</s>
What are the words of House Oakheart?
"Our Roots Go Deep"
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### Instruction: What are the words of House Oakheart? ### Context: ### Answer: "Our Roots Go Deep"</s>
What do the different ski slope colors mean?
1) Green (usually represented by a circle): these are beginner slopes and are not very steep. A New skier should be able to navigate these without losing control or catching too much speed, but more advanced skiers tend to find these too flat. 2) Blue (usually represented by a square): These are intermediate slopes with some steeper or more narrow runs. Skiers of all skill levels can enjoy these, but beginners might need to take it slow on some of the steeper parts. 3) Black (usually represented by a diamond): These are for advanced skiers only and have steep drops and/or obstacles. 4) Double Black (usually represented by two diamonds): These are only for the most experienced and advanced skiers and usually include extreme drops with significant obstacles.
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### Instruction: What do the different ski slope colors mean? ### Context: ### Answer: 1) Green (usually represented by a circle): these are beginner slopes and are not very steep. A New skier should be able to navigate these without losing control or catching too much speed, but more advanced skiers tend to find these too flat. 2) Blue (usually represented by a square): These are intermediate slopes with some steeper or more narrow runs. Skiers of all skill levels can enjoy these, but beginners might need to take it slow on some of the steeper parts. 3) Black (usually represented by a diamond): These are for advanced skiers only and have steep drops and/or obstacles. 4) Double Black (usually represented by two diamonds): These are only for the most experienced and advanced skiers and usually include extreme drops with significant obstacles.</s>
How large is a regulation size basketball in the NBA?
The official size of the basketball used by the NBA is 29.5 inches in circumference.
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### Instruction: How large is a regulation size basketball in the NBA? ### Context: ### Answer: The official size of the basketball used by the NBA is 29.5 inches in circumference.</s>
Where is the Mall of America located?
The Mall of America is located in Bloomington, Minnesota, USA.
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### Instruction: Where is the Mall of America located? ### Context: ### Answer: The Mall of America is located in Bloomington, Minnesota, USA.</s>
How many continents are in the world?
There are seven continents in the world
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### Instruction: How many continents are in the world? ### Context: ### Answer: There are seven continents in the world</s>
What is the difference between a kidnapping and a vacation?
A kidnapping is when someone is abducted against their will, whereas a vacation is when someone takes time away from their work or school, typically choosing to travel somewhere for pleasure.
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### Instruction: What is the difference between a kidnapping and a vacation? ### Context: ### Answer: A kidnapping is when someone is abducted against their will, whereas a vacation is when someone takes time away from their work or school, typically choosing to travel somewhere for pleasure.</s>
Who was the mascot of 13th South Asian Games (SAG)
A pair of blackbucks
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### Instruction: Who was the mascot of 13th South Asian Games (SAG) ### Context: ### Answer: A pair of blackbucks</s>
Name some famous books on philosophy?
Meditations by Marcus Aurelius. Man's Search for Meaning by Viktor Frankl. The Story of Philosophy by Will Durant. The Republic by Plato. Discourses by Epictetus.
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### Instruction: Name some famous books on philosophy? ### Context: ### Answer: Meditations by Marcus Aurelius. Man's Search for Meaning by Viktor Frankl. The Story of Philosophy by Will Durant. The Republic by Plato. Discourses by Epictetus.</s>
Which city is the capital city of California?
Sacramento is the capital of California.
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### Instruction: Which city is the capital city of California? ### Context: ### Answer: Sacramento is the capital of California.</s>
What recording artist has won the most Grammys?
Beyonce, a singer-songwriter who has been active since the 1990s, holds the record for most Grammys won as of 2023 with 32 awards.
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### Instruction: What recording artist has won the most Grammys? ### Context: ### Answer: Beyonce, a singer-songwriter who has been active since the 1990s, holds the record for most Grammys won as of 2023 with 32 awards.</s>
What coloring of cat is almost always male?
Orange cats are generally male.
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### Instruction: What coloring of cat is almost always male? ### Context: ### Answer: Orange cats are generally male.</s>
What is structural genomics?
Structural genomics seeks to describe the 3-dimensional structure of every protein encoded by a given genome. This genome-based approach allows for a high-throughput method of structure determination by a combination of experimental and modeling approaches. The principal difference between structural genomics and traditional structural prediction is that structural genomics attempts to determine the structure of every protein encoded by the genome, rather than focusing on one particular protein. With full-genome sequences available, structure prediction can be done more quickly through a combination of experimental and modeling approaches, especially because the availability of large number of sequenced genomes and previously solved protein structures allows scientists to model protein structure on the structures of previously solved homologs. Because protein structure is closely linked with protein function, the structural genomics has the potential to inform knowledge of protein function. In addition to elucidating protein functions, structural genomics can be used to identify novel protein folds and potential targets for drug discovery. Structural genomics involves taking a large number of approaches to structure determination, including experimental methods using genomic sequences or modeling-based approaches based on sequence or structural homology to a protein of known structure or based on chemical and physical principles for a protein with no homology to any known structure. As opposed to traditional structural biology, the determination of a protein structure through a structural genomics effort often (but not always) comes before anything is known regarding the protein function. This raises new challenges in structural bioinformatics, i.e. determining protein function from its 3D structure. Structural genomics emphasizes high throughput determination of protein structures. This is performed in dedicated centers of structural genomics. While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large-scale cloning, expression and purification. One main advantage of this approach is economy of scale. On the other hand, the scientific value of some resultant structures is at times questioned. A Science article from January 2006 analyzes the structural genomics field. One advantage of structural genomics, such as the Protein Structure Initiative, is that the scientific community gets immediate access to new structures, as well as to reagents such as clones and protein. A disadvantage is that many of these structures are of proteins of unknown function and do not have corresponding publications. This requires new ways of communicating this structural information to the broader research community. The Bioinformatics core of the Joint center for structural genomics (JCSG) has recently developed a wiki-based approach namely Open protein structure annotation network (TOPSAN) for annotating protein structures emerging from high-throughput structural genomics centers.
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### Instruction: What is structural genomics? ### Context: ### Answer: Structural genomics seeks to describe the 3-dimensional structure of every protein encoded by a given genome. This genome-based approach allows for a high-throughput method of structure determination by a combination of experimental and modeling approaches. The principal difference between structural genomics and traditional structural prediction is that structural genomics attempts to determine the structure of every protein encoded by the genome, rather than focusing on one particular protein. With full-genome sequences available, structure prediction can be done more quickly through a combination of experimental and modeling approaches, especially because the availability of large number of sequenced genomes and previously solved protein structures allows scientists to model protein structure on the structures of previously solved homologs. Because protein structure is closely linked with protein function, the structural genomics has the potential to inform knowledge of protein function. In addition to elucidating protein functions, structural genomics can be used to identify novel protein folds and potential targets for drug discovery. Structural genomics involves taking a large number of approaches to structure determination, including experimental methods using genomic sequences or modeling-based approaches based on sequence or structural homology to a protein of known structure or based on chemical and physical principles for a protein with no homology to any known structure. As opposed to traditional structural biology, the determination of a protein structure through a structural genomics effort often (but not always) comes before anything is known regarding the protein function. This raises new challenges in structural bioinformatics, i.e. determining protein function from its 3D structure. Structural genomics emphasizes high throughput determination of protein structures. This is performed in dedicated centers of structural genomics. While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large-scale cloning, expression and purification. One main advantage of this approach is economy of scale. On the other hand, the scientific value of some resultant structures is at times questioned. A Science article from January 2006 analyzes the structural genomics field. One advantage of structural genomics, such as the Protein Structure Initiative, is that the scientific community gets immediate access to new structures, as well as to reagents such as clones and protein. A disadvantage is that many of these structures are of proteins of unknown function and do not have corresponding publications. This requires new ways of communicating this structural information to the broader research community. The Bioinformatics core of the Joint center for structural genomics (JCSG) has recently developed a wiki-based approach namely Open protein structure annotation network (TOPSAN) for annotating protein structures emerging from high-throughput structural genomics centers.</s>
Who prepares the Global Hunger Index?
Global Hunger Index is jointly prepared by Welhunger Life and Concern Worldwide
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### Instruction: Who prepares the Global Hunger Index? ### Context: ### Answer: Global Hunger Index is jointly prepared by Welhunger Life and Concern Worldwide</s>
Who is the author of books "It Starts With Us" and "It Ends With Us"?
Colleen Hoover is the author of bestselling books "It Starts With Us" and "It Ends With Us".
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### Instruction: Who is the author of books "It Starts With Us" and "It Ends With Us"? ### Context: ### Answer: Colleen Hoover is the author of bestselling books "It Starts With Us" and "It Ends With Us".</s>
Where is the first Summer Olympics held?
Athens, Greece 1896
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### Instruction: Where is the first Summer Olympics held? ### Context: ### Answer: Athens, Greece 1896</s>
What are financial services?
Financial services are economic services provided by the finance industry, which together encompass a broad range of service sector firms that provide financial management, including credit unions, banks, credit-card companies, insurance companies, accountancy companies, consumer-finance companies, stock brokerages, investment funds, individual asset managers, and some government-sponsored enterprises.
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### Instruction: What are financial services? ### Context: ### Answer: Financial services are economic services provided by the finance industry, which together encompass a broad range of service sector firms that provide financial management, including credit unions, banks, credit-card companies, insurance companies, accountancy companies, consumer-finance companies, stock brokerages, investment funds, individual asset managers, and some government-sponsored enterprises.</s>
How many episodes of the second season of Game of Thrones did Alan Taylor direct?
Alan Taylor directed the first two, eighth, and last episodes of the second season of Game of Thrones.
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### Instruction: How many episodes of the second season of Game of Thrones did Alan Taylor direct? ### Context: ### Answer: Alan Taylor directed the first two, eighth, and last episodes of the second season of Game of Thrones.</s>
Why is the Bay Area football team called the 49ers?
The "49ers" is the nickname for those who flocked to Northern California in 1849 hoping to take advantage of the gold rush. The 49ers were also the first NFL team, and in fact, the first major professional sports team to originate on the West Coast.
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### Instruction: Why is the Bay Area football team called the 49ers? ### Context: ### Answer: The "49ers" is the nickname for those who flocked to Northern California in 1849 hoping to take advantage of the gold rush. The 49ers were also the first NFL team, and in fact, the first major professional sports team to originate on the West Coast.</s>
How many cents do I have if I have 3 dollars and a dime?
If you have 3 dollars and a dime, you have 310 cents in total.
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### Instruction: How many cents do I have if I have 3 dollars and a dime? ### Context: ### Answer: If you have 3 dollars and a dime, you have 310 cents in total.</s>
Name some titles from the Goosebumps series.
Welcome to Dead House, Monster Blood, Say Cheese and Die!, The Cuckoo Clock of Doom, Revenge of the Lawn Gnomes, The Horror at Camp Jellyjam
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### Instruction: Name some titles from the Goosebumps series. ### Context: ### Answer: Welcome to Dead House, Monster Blood, Say Cheese and Die!, The Cuckoo Clock of Doom, Revenge of the Lawn Gnomes, The Horror at Camp Jellyjam</s>
What is the genomics of disease?
With the advent of next-generation sequencing we are obtaining enough sequence data to map the genes of complex diseases including infertility, breast cancer or Alzheimer's disease. Genome-wide association studies are a useful approach to pinpoint the mutations responsible for such complex diseases. Through these studies, thousands of DNA variants have been identified that are associated with similar diseases and traits. Furthermore, the possibility for genes to be used at prognosis, diagnosis or treatment is one of the most essential applications. Many studies are discussing both the promising ways to choose the genes to be used and the problems and pitfalls of using genes to predict disease presence or prognosis. Genome-wide association studies have successfully identified thousands of common genetic variants for complex diseases and traits; however, these common variants only explain a small fraction of heritability. Rare variants may account for some of the missing heritability. Large-scale whole genome sequencing studies have rapidly sequenced millions of whole genomes, and such studies have identified hundreds of millions of rare variants. Functional annotations predict the effect or function of a genetic variant and help to prioritize rare functional variants, and incorporating these annotations can effectively boost the power of genetic association of rare variants analysis of whole genome sequencing studies. Some tools have been developed to provide all-in-one rare variant association analysis for whole-genome sequencing data, including integration of genotype data and their functional annotations, association analysis, result summary and visualization. Meta-analysis of whole genome sequencing studies provides an attractive solution to the problem of collecting large sample sizes for discovering rare variants associated with complex phenotypes.
open_qa
### Instruction: What is the genomics of disease? ### Context: ### Answer: With the advent of next-generation sequencing we are obtaining enough sequence data to map the genes of complex diseases including infertility, breast cancer or Alzheimer's disease. Genome-wide association studies are a useful approach to pinpoint the mutations responsible for such complex diseases. Through these studies, thousands of DNA variants have been identified that are associated with similar diseases and traits. Furthermore, the possibility for genes to be used at prognosis, diagnosis or treatment is one of the most essential applications. Many studies are discussing both the promising ways to choose the genes to be used and the problems and pitfalls of using genes to predict disease presence or prognosis. Genome-wide association studies have successfully identified thousands of common genetic variants for complex diseases and traits; however, these common variants only explain a small fraction of heritability. Rare variants may account for some of the missing heritability. Large-scale whole genome sequencing studies have rapidly sequenced millions of whole genomes, and such studies have identified hundreds of millions of rare variants. Functional annotations predict the effect or function of a genetic variant and help to prioritize rare functional variants, and incorporating these annotations can effectively boost the power of genetic association of rare variants analysis of whole genome sequencing studies. Some tools have been developed to provide all-in-one rare variant association analysis for whole-genome sequencing data, including integration of genotype data and their functional annotations, association analysis, result summary and visualization. Meta-analysis of whole genome sequencing studies provides an attractive solution to the problem of collecting large sample sizes for discovering rare variants associated with complex phenotypes.</s>
What wine is the Oregon Willamette Valley known for?
Oregon's Willamette Valley is known best for producing renowned Pinot Noirs.
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### Instruction: What wine is the Oregon Willamette Valley known for? ### Context: ### Answer: Oregon's Willamette Valley is known best for producing renowned Pinot Noirs.</s>
What are the three main nutrient groups?
The three main nutrient groups, also called macronutrients and macros for short, are protein, carbohydrates, and fat.
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### Instruction: What are the three main nutrient groups? ### Context: ### Answer: The three main nutrient groups, also called macronutrients and macros for short, are protein, carbohydrates, and fat.</s>
What are the differences between the New York Giants and New York Jets?
The New York Giants and New York Jets are both professional football teams in the NFL who play in the New York Metropolitan area. Both teams play in MetLife stadium which used to be called Giants stadium in East Rutherford, NJ. Their fan bases live in New Jersey and New York primarily. The Jets primary color is Green, while the Giants are blue.
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### Instruction: What are the differences between the New York Giants and New York Jets? ### Context: ### Answer: The New York Giants and New York Jets are both professional football teams in the NFL who play in the New York Metropolitan area. Both teams play in MetLife stadium which used to be called Giants stadium in East Rutherford, NJ. Their fan bases live in New Jersey and New York primarily. The Jets primary color is Green, while the Giants are blue.</s>
What is Jon Snow's true name?
Aegon Targaryen
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### Instruction: What is Jon Snow's true name? ### Context: ### Answer: Aegon Targaryen</s>