This author of "Orlando" based her 1922 novel "Jacob's Room" on the life & death of her brother Thoby
... Jacob is based on Woolf's older brother Thoby Stephen, 
who died of a fever in 1906, when he ... Orlando, based on Woolf's friend Vita 
Sackville-West, lives 400 years and ... A Writer's Diary (UK 1953).