The Tiber runs through this hilly Italian region
Under it (two tunnels) runs the Autostrada della Cisa 
between Spezia and... [DOC] [TLE] Tiber River | river, Italy | Britannica.com [PAR] It is only in modern times that the Tiber has flowed through Rome between ... Italy 
 in Italy: Rivers ...Abruzzo, and Marche regions.