In the mid 1500's Sofonisba Anguissola was a painter at the court of this Spanish king & did his portrait
It's About Time: 1500s 
Women Artists ..... pink is wonderful Portrait of an Unknown Man and Woman (
once called 'Vasari and His Wife' by Sofonisba Anguissola) by Northern Italian 
School... [DOC] [TLE] Spanish court lady, probably Isabel de Valois, by Sofonisba ... [PAR] Spanish court lady, probably Isabel de Valois, by Sofonisba Anguissola | See ... 
1500 - 1600 Spanish Renaissance  Retrato de mujer, 1560, Sofonisba 
Anguissola Portrait of a Woman ...... A talented painter, this is a portrait of his wife 
Isabella.