The reign in Spain for this queen was from 1474 to 1504
.... Isabella officially 
withdrew from governmental affairs on 14 September 1504 and she died that 
same... [DOC] [TLE] Isabella I | queen of Spain | Britannica.com [PAR] Queen of Castile (14741504) and of Aragon (14791504), ruling the two 
kingdoms ... Isabella I, byname Isabella the Catholic, Spanish Isabel la Catlica (
born April 22, ...