As a human guinea pig, Jesse Lazear helped Walter Reed prove this was spread by mosquitoes
In 1900 
he charged bacteriologists Dr. Jesse W. Lazear and James Carroll, ... which 
became the foundation for ethical human experimentation protocols... [DOC] [TLE] WALTER REED [PAR] Of course you might protest that fate hit Jesse Lazear a hard knockbut it was 
his .... To make any kind of experiment to prove mosquitoes carry yellow fever 
you ...