This title assassin seen here debuted on MTV's Liquid Television in 1991.  Charlize Theron played her in the live action film
[DOC] [TLE] MTV Oddities presents The Head | TV Shows | Pinterest | Cadeaux ... [PAR] Liquid Television (1991-94, MTV)  This Emmy Award-winning animated ... MTV 
was so much better back n the day when they actually played only music videos 
.... a live action movie that's faithful to the original and captures her 
kickassedness .... Charlize Theron in Paramount Pictures' action/adventure Aeon 
Flux - 2005.