Introduced in 1986, it's one of the most widely prescribed antidepressants in history
In all but one of the studies (see Kanner et al., 2000), patients were... [DOC] [TLE] Fatal Toxicity Of Antidepressant Drugs In Overdose - JStor [PAR] antidepressants introduced since 1973, considered as a group, ... its intrinsic 
toxicity and its availability.12 It is impossible to estimate the numbers of people 
treated with each drug, but Britain is one of .... tricyclic group of drugs are widely 
believed to be among the most toxic.