An acceptable cross-platform GUI toolkit?
coryrc: wxWidgets is "big" because it has features. Considering it meets all your other criteria (aka features), in addition to ones you'll only find out you need halfway through a project, I would look closer at it. Use wxGlade and wxPython if you want easy, C++ if you demand compiled. Use dabo (http://www.dabodev.com) if you are interfacing with databases.