How do you deal with customer support requests?
byoung2: Are you talking about keeping the emails sorted out, and remembering who answered what?  For that I use Email Center Pro (http://www.emailcenterpro.com).  If you have a catch-all email address like support@mycompany.com, you set it up to be checked by Email Center Pro, and you can assign incoming emails to specific users, and track followup.  It shows threaded conversations with comments alongside, and you can save templates for common responses.