Using alternative keyboard layouts?
patrickg-zill: They are great if you only use a few systems.  However if you are working on other people's systems or some other case where you are not the sole user of the machine, it is difficult to deal with switching between QWERTY and Dvorak; which is the main reason I do not use Dvorak.  A friend uses Dvorak exclusively and it works well for him - he only touches his own systems.