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stringlengths
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3
3313-GP1
GP1
3313
HSPA9
[ "CRP40", "CSA", "EVPLS", "GRP-75", "GRP75", "HEL-S-124m", "HSPA9B", "MOT", "MOT2", "MTHSP75", "PBP74", "SAAN", "SIDBA4", "stress-70 protein, mitochondrial", "75 kDa glucose-regulated protein", "catecholamine-regulated protein 40", "heat shock 70kD protein 9B", "mortalin, perinuclear", "mortalin-2", "mortalin2", "p66-mortalin", "peptide-binding protein 74" ]
[ "REACT:R-HSA-2262752", "REACT:R-HSA-3371556", "REACT:R-HSA-392499", "REACT:R-HSA-1268020", "REACT:R-HSA-3371453", "KEGG:hsa03018", "KEGG:hsa05152" ]
[ "Cellular responses to stress", "Cellular response to heat stress", "Metabolism of proteins", "Mitochondrial protein import", "Regulation of HSF1-mediated heat shock response", "RNA degradation", "Tuberculosis" ]
[]
[ [], [], [], [], [], [], [] ]
G alpha (i) signalling events
Mitophagy - animal
G alpha (12/13) signalling events
Cellular responses to stress
3
84864-GP1
GP1
84864
RIOX2
[ "ribosomal oxygenase 2", "JMJD10", "MDIG", "MINA", "MINA53", "NO52", "ROX", "ribosomal oxygenase 2", "MYC induced nuclear antigen", "MYC-induced nuclear antigen 53", "mineral dust induced gene protein", "nucleolar protein 52", "ribosomal oxygenase MINA" ]
[ "REACT:R-HSA-3247509", "REACT:R-HSA-4839726", "REACT:R-HSA-3214842" ]
[ "Chromatin modifying enzymes", "Chromatin organization", "HDMs demethylate histones" ]
[]
[ [], [], [] ]
ABC transporters
Cell Cycle
Chromatin modifying enzymes
Alzheimer's disease
2
11119-GP1
GP1
11119
BTN3A1
[ "butyrophilin subfamily 3 member A1", "BT3.1", "BTF5", "BTN3.1", "CD277", "butyrophilin subfamily 3 member A1" ]
[ "REACT:R-HSA-1280218", "REACT:R-HSA-168256" ]
[ "Adaptive Immune System", "Immune System" ]
[]
[ [], [] ]
Metabolism
Hemostasis
Butanoate metabolism
Adaptive Immune System
3
4881-GP1
GP1
4881
NPR1
[ "natriuretic peptide receptor 1", "ANPRA", "ANPa", "GUC2A", "GUCY2A", "NPRA", "atrial natriuretic peptide receptor 1", "ANP-A", "ANPR-A", "GC-A", "NPR-A", "atrionatriuretic peptide receptor A", "guanylate cyclase A", "natriuretic peptide A type receptor", "natriuretic peptide receptor A", "testicular tissue protein Li 20" ]
[ "KEGG:hsa04925", "KEGG:hsa04024", "REACT:R-HSA-5576891", "KEGG:hsa04022", "KEGG:hsa_M00694", "REACT:R-HSA-397014", "KEGG:hsa04921", "REACT:R-HSA-5578768", "KEGG:hsa00230", "KEGG:hsa04923", "KEGG:hsa04924", "KEGG:hsa04270" ]
[ "Aldosterone synthesis and secretion", "cAMP signaling pathway", "Cardiac conduction", "cGMP-PKG signaling pathway", "cGMP signaling", "Muscle contraction", "Oxytocin signaling pathway", "Physiological factors", "Purine metabolism", "Regulation of lipolysis in adipocytes", "Renin secretion", "Vascular smooth muscle contraction" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [] ]
Herpes simplex infection
Aldosterone synthesis and secretion
Neuroactive ligand-receptor interaction
Elastic fibre formation
1
23072-GP1
GP1
23072
HECW1
[ "NEDL1" ]
[ "REACT:R-HSA-4641258", "REACT:R-HSA-195721", "REACT:R-HSA-162582", "REACT:R-HSA-201681" ]
[ "Degradation of DVL", "Signaling by Wnt", "Signal Transduction", "TCF dependent signaling in response to WNT" ]
[]
[ [], [], [], [] ]
ER to Golgi Anterograde Transport
Degradation of DVL
Gap junction
Tight junction
1
55775-GP1
GP1
55775
TDP1
[]
[ "REACT:R-HSA-5693532", "REACT:R-HSA-73894" ]
[ "DNA Double-Strand Break Repair", "DNA Repair" ]
[]
[ [], [] ]
Hippo signaling
DNA Double-Strand Break Repair
Mitophagy - animal
Bile acid and bile salt metabolism
1
10079-GP1
GP1
10079
ATP9A
[ "ATPIIA", "ATPase, class II, type 9A" ]
[ "REACT:R-HSA-983712", "REACT:R-HSA-936837", "REACT:R-HSA-382551" ]
[ "Ion channel transport", "Ion transport by P-type ATPases", "Transmembrane transport of small molecules" ]
[]
[ [], [], [] ]
Fertilization
Ion channel transport
Autophagy - animal
Developmental Biology
1
3750-GP1
GP1
3750
KCND1
[ "potassium voltage-gated channel subfamily D member 1", "KV4.1", "potassium voltage-gated channel subfamily D member 1", "Shal-type potassium channel" ]
[ "REACT:R-HSA-5576891", "REACT:R-HSA-397014", "REACT:R-HSA-112316", "REACT:R-HSA-1296071", "REACT:R-HSA-1296072" ]
[ "Cardiac conduction", "Muscle contraction", "Neuronal System", "Potassium Channels", "Voltage gated Potassium channels" ]
[]
[ [], [], [], [], [] ]
Oocyte meiosis
Cell adhesion molecules (CAMs)
Cardiac conduction
Cul3-SPOP complex
2
9775-GP1
GP1
9775
EIF4A3
[ "eukaryotic translation initiation factor 4A3", "DDX48", "Fal1", "MUK34", "NMP265", "NUK34", "RCPS", "eIF-4A-III", "eIF4A-III", "eIF4AIII", "eukaryotic initiation factor 4A-III", "ATP-dependent RNA helicase DDX48", "DEAD box protein 48", "NMP 265", "nuclear matrix protein 265" ]
[ "REACT:R-HSA-1280215", "REACT:R-HSA-429914", "REACT:R-HSA-429947", "KEGG:hsa_M00430", "REACT:R-HSA-74160", "REACT:R-HSA-168256", "REACT:R-HSA-913531", "REACT:R-HSA-1169408", "REACT:R-HSA-72187", "REACT:R-HSA-72172", "REACT:R-HSA-72163", "KEGG:hsa03015", "REACT:R-HSA-73857", "REACT:R-HSA-73856", "KEGG:hsa03013", "KEGG:hsa03040" ]
[ "Cytokine Signaling in Immune system", "Deadenylation-dependent mRNA decay", "Deadenylation of mRNA", "Exon junction complex (EJC)", "Gene Expression", "Immune System", "Interferon Signaling", "ISG15 antiviral mechanism", "mRNA 3'-end processing", "mRNA Splicing", "mRNA Splicing - Major Pathway", "mRNA surveillance pathway", "RNA Polymerase II Transcription", "RNA Polymerase II Transcription Termination", "RNA transport", "Spliceosome" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [] ]
G alpha (i) signalling events
Cilium Assembly
Cytokine Signaling in Immune system
Carbon metabolism
2
23768-GP1
GP1
23768
FLRT2
[]
[ "REACT:R-HSA-190236", "REACT:R-HSA-5654736", "REACT:R-HSA-162582" ]
[ "Signaling by FGFR", "Signaling by FGFR1", "Signal Transduction" ]
[]
[ [], [], [] ]
G alpha (s) signalling events
Signaling by FGFR
Elastic fibre formation
Gap junction
1
1008-GP1
GP1
1008
CDH10
[ "cadherin 10", "cadherin-10", "T2-cadherin", "cadherin 10 type 2" ]
[ "REACT:R-HSA-418990", "REACT:R-HSA-1500931", "REACT:R-HSA-421270", "REACT:R-HSA-446728" ]
[ "Adherens junctions interactions", "Cell-Cell communication", "Cell-cell junction organization", "Cell junction organization" ]
[]
[ [], [], [], [] ]
Amoebiasis
Autophagy - animal
Adherens junctions interactions
GABAergic synapse
2
5627-GP1
GP1
5627
PROS1
[ "protein S", "PS21", "PS22", "PS23", "PS24", "PS25", "PSA", "THPH5", "THPH6", "vitamin K-dependent protein S", "protein S (alpha)", "protein Sa", "vitamin K-dependent plasma protein S" ]
[ "REACT:R-HSA-202733", "REACT:R-HSA-140875", "KEGG:hsa04610", "REACT:R-HSA-166658", "REACT:R-HSA-159740", "REACT:R-HSA-109582", "REACT:R-HSA-168256", "REACT:R-HSA-168249", "REACT:R-HSA-392499", "REACT:R-HSA-76002", "REACT:R-HSA-114608", "REACT:R-HSA-597592", "REACT:R-HSA-977606" ]
[ "Cell surface interactions at the vascular wall", "Common Pathway of Fibrin Clot Formation", "Complement and coagulation cascades", "Complement cascade", "Gamma-carboxylation of protein precursors", "Hemostasis", "Immune System", "Innate Immune System", "Metabolism of proteins", "Platelet activation, signaling and aggregation", "Platelet degranulation", "Post-translational protein modification", "Regulation of Complement cascade" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [] ]
RA biosynthesis pathway
Histidine catabolism
Cell surface interactions at the vascular wall
Acrosome Reaction
2
826-GP1
GP1
826
CAPNS1
[ "calpain small subunit 1", "CALPAIN4", "CANP", "CANPS", "CAPN4", "CDPS", "CSS1", "calpain small subunit 1", "CANP small subunit", "calcium-activated neutral proteinase small subunit", "calcium-dependent protease small subunit 1", "calcium-dependent protease, small subunit", "calpain regulatory subunit", "epididymis secretory sperm binding protein" ]
[ "REACT:R-HSA-1474228", "REACT:R-HSA-1266738", "REACT:R-HSA-1643685", "REACT:R-HSA-1474244", "REACT:R-HSA-6809371", "REACT:R-HSA-6805567", "REACT:R-HSA-8863678" ]
[ "Degradation of the extracellular matrix", "Developmental Biology", "Disease", "Extracellular matrix organization", "Formation of the cornified envelope", "Keratinization", "Neurodegenerative Diseases" ]
[]
[ [], [], [], [], [], [], [] ]
Amphetamine addiction
Cell Cycle
Degradation of the extracellular matrix
G alpha (q) signalling events
2
23479-GP1
GP1
23479
ISCU
[ "iron-sulfur cluster assembly enzyme", "2310020H20Rik", "HML", "ISU2", "NIFU", "NIFUN", "hnifU", "iron-sulfur cluster assembly enzyme ISCU, mitochondrial" ]
[ "REACT:R-HSA-1430728" ]
[ "Metabolism" ]
[]
[ [] ]
G alpha (s) signalling events
NF-kappa B signaling pathway
Metabolism
Budding and maturation of HIV virion
2
272-GP1
GP1
272
AMPD3
[ "AMP deaminase 3", "AMP aminohydrolase", "myoadenylate deaminase" ]
[ "REACT:R-HSA-168256", "REACT:R-HSA-168249", "KEGG:hsa01100", "REACT:R-HSA-1430728", "REACT:R-HSA-15869", "REACT:R-HSA-6798695", "KEGG:hsa00230", "REACT:R-HSA-73847", "REACT:R-HSA-74217" ]
[ "Immune System", "Innate Immune System", "Metabolic pathways", "Metabolism", "Metabolism of nucleotides", "Neutrophil degranulation", "Purine metabolism", "Purine metabolism", "Purine salvage" ]
[]
[ [], [], [], [], [], [], [], [], [] ]
Immune System
NOD-like receptor signaling pathway
Chemokine receptors bind chemokines
Ca2+ activated K+ channels
0
112950-GP1
GP1
112950
MED8
[ "mediator complex subunit 8", "ARC32", "mediator of RNA polymerase II transcription subunit 8" ]
[ "REACT:R-HSA-1266738", "REACT:R-HSA-74160", "REACT:R-HSA-212436", "KEGG:hsa05168", "REACT:R-HSA-1430728", "REACT:R-HSA-1989781" ]
[ "Developmental Biology", "Gene Expression", "Generic Transcription Pathway", "Herpes simplex infection", "Metabolism", "PPARA activates gene expression" ]
[]
[ [], [], [], [], [], [] ]
Activated TLR4 signalling
Degradation of DVL
Signaling by PTK6
Developmental Biology
3
8490-GP1
GP1
8490
RGS5
[ "regulator of G protein signaling 5", "MST092", "MST106", "MST129", "MSTP032", "MSTP092", "MSTP106", "MSTP129", "regulator of G-protein signaling 5" ]
[ "REACT:R-HSA-418594", "REACT:R-HSA-388396", "REACT:R-HSA-372790", "REACT:R-HSA-162582" ]
[ "G alpha (i) signalling events", "GPCR downstream signaling", "Signaling by GPCR", "Signal Transduction" ]
[]
[ [], [], [], [] ]
Cap binding complex
G alpha (i) signalling events
Branched-chain amino acid catabolism
Alcoholism
1
1660-GP1
GP1
1660
DHX9
[ "DExH-box helicase 9", "DDX9", "LKP", "NDH2", "NDHII", "RHA", "ATP-dependent RNA helicase A", "DEAH box protein 9", "DEAH-box helicase 9", "RNA helicase A", "leukophysin", "nuclear DNA helicase II" ]
[ "REACT:R-HSA-166054", "REACT:R-HSA-1834949", "REACT:R-HSA-74160", "REACT:R-HSA-168256", "REACT:R-HSA-168249", "REACT:R-HSA-72172", "REACT:R-HSA-72163", "REACT:R-HSA-168898" ]
[ "Activated TLR4 signalling", "Cytosolic sensors of pathogen-associated DNA", "Gene Expression", "Immune System", "Innate Immune System", "mRNA Splicing", "mRNA Splicing - Major Pathway", "Toll-Like Receptors Cascades" ]
[]
[ [], [], [], [], [], [], [], [] ]
Activated TLR4 signalling
Amphetamine addiction
Influenza A
Gap junction
0
731-GP1
GP1
731
C8A
[ "complement C8 alpha chain", "complement component C8 alpha chain", "complement component 8 alpha subunit", "complement component 8 subunit alpha", "complement component 8, alpha polypeptide" ]
[ "KEGG:hsa05146", "KEGG:hsa04610", "REACT:R-HSA-166658", "REACT:R-HSA-168256", "REACT:R-HSA-168249", "KEGG:hsa05020", "REACT:R-HSA-977606", "KEGG:hsa05322", "REACT:R-HSA-166665" ]
[ "Amoebiasis", "Complement and coagulation cascades", "Complement cascade", "Immune System", "Innate Immune System", "Prion diseases", "Regulation of Complement cascade", "Systemic lupus erythematosus", "Terminal pathway of complement" ]
[]
[ [], [], [], [], [], [], [], [], [] ]
Pathways in cancer
Cell-Cell communication
Amoebiasis
Ubiquitin mediated proteolysis
2
6147-GP1
GP1
6147
RPL23A
[ "ribosomal protein L23a", "MDA20", "60S ribosomal protein L23a", "large ribosomal subunit protein uL23", "melanoma differentiation-associated gene 20" ]
[ "REACT:R-HSA-72737", "REACT:R-HSA-1643685", "REACT:R-HSA-156842", "REACT:R-HSA-72613", "REACT:R-HSA-72764", "REACT:R-HSA-72689", "REACT:R-HSA-74160", "REACT:R-HSA-5663205", "REACT:R-HSA-168254", "REACT:R-HSA-168255", "REACT:R-HSA-1430728", "REACT:R-HSA-71291", "REACT:R-HSA-392499", "REACT:R-HSA-156902", "KEGG:hsa03010", "KEGG:hsa_M00177", "REACT:R-HSA-72312", "REACT:R-HSA-2408522", "REACT:R-HSA-2408557", "REACT:R-HSA-72766", "REACT:R-HSA-192823" ]
[ "Cap-dependent Translation Initiation", "Disease", "Eukaryotic Translation Elongation", "Eukaryotic Translation Initiation", "Eukaryotic Translation Termination", "Formation of a pool of free 40S subunits", "Gene Expression", "Infectious disease", "Influenza Infection", "Influenza Life Cycle", "Metabolism", "Metabolism of amino acids and derivatives", "Metabolism of proteins", "Peptide chain elongation", "Ribosome", "Ribosome, eukaryotes", "rRNA processing", "Selenoamino acid metabolism", "Selenocysteine synthesis", "Translation", "Viral mRNA Translation" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [] ]
Linoleic acid (LA) metabolism
Glycerophospholipid metabolism
Mitochondrial translation
Cap-dependent Translation Initiation
3
23305-GP1
GP1
23305
ACSL6
[ "ACS2", "FACL6", "LACS 6", "LACS2", "LACS5" ]
[ "KEGG:hsa04920", "KEGG:hsa00061", "KEGG:hsa00071", "KEGG:hsa01212", "KEGG:hsa04216", "KEGG:hsa01100", "REACT:R-HSA-1430728", "KEGG:hsa04146", "KEGG:hsa03320", "REACT:R-HSA-75109" ]
[ "Adipocytokine signaling pathway", "Fatty acid biosynthesis", "Fatty acid degradation", "Fatty acid metabolism", "Ferroptosis", "Metabolic pathways", "Metabolism", "Peroxisome", "PPAR signaling pathway", "Triglyceride Biosynthesis" ]
[]
[ [], [], [], [], [], [], [], [], [], [] ]
Base Excision Repair
Adipocytokine signaling pathway
Collecting duct acid secretion
Base excision repair
1
390053-GP1
GP1
390053
OR52A4P
[ "putative olfactory receptor 52A4" ]
[ "REACT:R-HSA-388396", "REACT:R-HSA-381753", "REACT:R-HSA-372790", "REACT:R-HSA-162582" ]
[ "GPCR downstream signaling", "Olfactory Signaling Pathway", "Signaling by GPCR", "Signal Transduction" ]
[]
[ [], [], [], [] ]
Basal cell carcinoma
GPCR downstream signaling
Endocytosis
Acute myeloid leukemia
1
1394-GP1
GP1
1394
CRHR1
[ "corticotropin releasing hormone receptor 1", "CRF-R", "CRF-R-1", "CRF-R1", "CRF1", "CRFR-1", "CRFR1", "CRHR1L", "corticotropin-releasing factor receptor 1", "seven transmembrane helix receptor" ]
[ "REACT:R-HSA-373080", "REACT:R-HSA-418555", "REACT:R-HSA-388396", "REACT:R-HSA-500792", "KEGG:hsa04730", "KEGG:hsa04080", "REACT:R-HSA-372790", "REACT:R-HSA-162582" ]
[ "Class B/2 (Secretin family receptors)", "G alpha (s) signalling events", "GPCR downstream signaling", "GPCR ligand binding", "Long-term depression", "Neuroactive ligand-receptor interaction", "Signaling by GPCR", "Signal Transduction" ]
[]
[ [], [], [], [], [], [], [], [] ]
Degradation of DVL
Class B/2 (Secretin family receptors)
DNA Double-Strand Break Repair
African trypanosomiasis
1
4493-GP1
GP1
4493
MT1E
[ "metallothionein 1E", "MT-IE", "MTD", "metallothionein-1E", "metallothionein 1E (functional)", "metallothionein D", "metallothionein-IE" ]
[ "REACT:R-HSA-1430728", "REACT:R-HSA-5661231", "KEGG:hsa04978", "REACT:R-HSA-5660526" ]
[ "Metabolism", "Metallothioneins bind metals", "Mineral absorption", "Response to metal ions" ]
[]
[ [], [], [], [] ]
Dilated cardiomyopathy
ARMS-mediated activation
Metabolism
Amine ligand-binding receptors
2
645745-GP1
GP1
645745
MT1HL1
[ "metallothionein 1H like 1", "MT1P2", "MT-1H-like protein" ]
[ "KEGG:hsa04978" ]
[ "Mineral absorption" ]
[]
[ [] ]
Ubiquitin mediated proteolysis
Chemokine receptors bind chemokines
Apoptosis - multiple species
Mineral absorption
3
3187-GP1
GP1
3187
HNRNPH1
[ "HNRPH", "HNRPH1", "epididymis secretory sperm binding protein" ]
[ "REACT:R-HSA-6803529", "REACT:R-HSA-74160", "REACT:R-HSA-72172", "REACT:R-HSA-72163", "REACT:R-HSA-190236", "REACT:R-HSA-5654738", "REACT:R-HSA-162582" ]
[ "FGFR2 alternative splicing", "Gene Expression", "mRNA Splicing", "mRNA Splicing - Major Pathway", "Signaling by FGFR", "Signaling by FGFR2", "Signal Transduction" ]
[]
[ [], [], [], [], [], [], [] ]
FGFR2 alternative splicing
Disease
Salivary secretion
Arachidonic acid metabolism
0
92552-GP1
GP1
92552
ATXN3L
[ "ataxin 3 like", "MJDL", "ataxin-3-like protein", "machado-Joseph disease protein 1-like", "putative ataxin-3-like protein" ]
[ "REACT:R-HSA-5688426", "REACT:R-HSA-5689877", "REACT:R-HSA-392499", "REACT:R-HSA-597592" ]
[ "Deubiquitination", "Josephin domain DUBs", "Metabolism of proteins", "Post-translational protein modification" ]
[]
[ [], [], [], [] ]
PI3K-Akt signaling pathway
Deubiquitination
Gap junction
Cell cycle
1
483-GP1
GP1
483
ATP1B3
[ "ATPB-3", "CD298", "sodium pump subunit beta-3" ]
[ "KEGG:hsa04261", "REACT:R-HSA-210991", "KEGG:hsa04976", "KEGG:hsa04024", "KEGG:hsa04973", "REACT:R-HSA-5576891", "KEGG:hsa04260", "REACT:R-HSA-202733", "KEGG:hsa04022", "KEGG:hsa04971", "REACT:R-HSA-109582", "KEGG:hsa04911", "REACT:R-HSA-983712", "REACT:R-HSA-5578775", "REACT:R-HSA-936837", "KEGG:hsa04978", "REACT:R-HSA-397014", "KEGG:hsa04972", "KEGG:hsa04974", "KEGG:hsa04964", "KEGG:hsa04970", "KEGG:hsa04919", "KEGG:hsa04918", "REACT:R-HSA-382551" ]
[ "Adrenergic signaling in cardiomyocytes", "Basigin interactions", "Bile secretion", "cAMP signaling pathway", "Carbohydrate digestion and absorption", "Cardiac conduction", "Cardiac muscle contraction", "Cell surface interactions at the vascular wall", "cGMP-PKG signaling pathway", "Gastric acid secretion", "Hemostasis", "Insulin secretion", "Ion channel transport", "Ion homeostasis", "Ion transport by P-type ATPases", "Mineral absorption", "Muscle contraction", "Pancreatic secretion", "Protein digestion and absorption", "Proximal tubule bicarbonate reclamation", "Salivary secretion", "Thyroid hormone signaling pathway", "Thyroid hormone synthesis", "Transmembrane transport of small molecules" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [] ]
Fertilization
Deubiquitination
Adrenergic signaling in cardiomyocytes
Mitochondrial translation
2
6421-GP1
GP1
6421
SFPQ
[ "POMP100", "PPP1R140", "PSF", "100 kDa DNA-pairing protein", "PTB-associated splicing factor", "epididymis secretory sperm binding protein", "polypyrimidine tract binding protein associated", "protein phosphatase 1, regulatory subunit 140" ]
[ "REACT:R-HSA-8848021", "REACT:R-HSA-162582" ]
[ "Signaling by PTK6", "Signal Transduction" ]
[]
[ [], [] ]
Cell-Cell communication
Signaling by PTK6
Bladder cancer
Gap junction
1
84747-GP1
GP1
84747
UNC119B
[ "POC7B", "protein unc-119 homolog B", "unc-119 homolog B" ]
[ "REACT:R-HSA-5620920", "REACT:R-HSA-5617833", "REACT:R-HSA-1852241" ]
[ "Cargo trafficking to the periciliary membrane", "Cilium Assembly", "Organelle biogenesis and maintenance" ]
[]
[ [], [], [] ]
Acrosome Reaction
Cargo trafficking to the periciliary membrane
ABC transporters
Heme biosynthesis
1
55215-GP1
GP1
55215
FANCI
[ "FA complementation group I", "KIAA1794", "Fanconi anemia group I protein", "Fanconi anemia complementation group I" ]
[ "REACT:R-HSA-73894", "KEGG:hsa03460", "REACT:R-HSA-6783310", "REACT:R-HSA-74160", "REACT:R-HSA-212436", "REACT:R-HSA-3700989" ]
[ "DNA Repair", "Fanconi anemia pathway", "Fanconi Anemia Pathway", "Gene Expression", "Generic Transcription Pathway", "Transcriptional Regulation by TP53" ]
[]
[ [], [], [], [], [], [] ]
Intra-Golgi traffic
Epstein-Barr virus infection
G alpha (12/13) signalling events
DNA Repair
3
6565-GP1
GP1
6565
SLC15A2
[ "solute carrier family 15 member 2", "PEPT2", "solute carrier family 15 member 2", "peptide transporter 2" ]
[ "REACT:R-HSA-425407", "REACT:R-HSA-382551" ]
[ "SLC-mediated transmembrane transport", "Transmembrane transport of small molecules" ]
[]
[ [], [] ]
Biological oxidations
Dectin-2 family
Neuronal System
SLC-mediated transmembrane transport
3
6523-GP1
GP1
6523
SLC5A1
[ "solute carrier family 5 member 1", "D22S675", "NAGT", "SGLT1", "sodium/glucose cotransporter 1", "Na+/glucose cotransporter 1", "high affinity sodium-glucose cotransporter" ]
[ "KEGG:hsa04976", "KEGG:hsa04973", "REACT:R-HSA-189200", "REACT:R-HSA-429593", "REACT:R-HSA-1430728", "REACT:R-HSA-71387", "KEGG:hsa04978", "REACT:R-HSA-428808", "REACT:R-HSA-425407", "REACT:R-HSA-382551" ]
[ "Bile secretion", "Carbohydrate digestion and absorption", "Hexose transport", "Inositol transporters", "Metabolism", "Metabolism of carbohydrates", "Mineral absorption", "Na+-dependent glucose transporters", "SLC-mediated transmembrane transport", "Transmembrane transport of small molecules" ]
[]
[ [], [], [], [], [], [], [], [], [], [] ]
Axon guidance
Budding and maturation of HIV virion
Bile secretion
Biosynthesis of amino acids
2
7057-GP1
GP1
7057
THBS1
[ "thrombospondin 1", "TSP", "TSP-1", "TSP1", "thrombospondin-1", "glycoprotein G", "thrombospondin-p50" ]
[ "KEGG:hsa05219", "REACT:R-HSA-1643685", "REACT:R-HSA-3781865", "KEGG:hsa04512", "REACT:R-HSA-1474244", "KEGG:hsa04510", "REACT:R-HSA-109582", "REACT:R-HSA-216083", "KEGG:hsa05144", "REACT:R-HSA-392499", "KEGG:hsa05206", "REACT:R-HSA-5173105", "KEGG:hsa04115", "KEGG:hsa04145", "KEGG:hsa04151", "REACT:R-HSA-76002", "REACT:R-HSA-114608", "REACT:R-HSA-597592", "KEGG:hsa05205", "KEGG:hsa04015", "REACT:R-HSA-186797", "REACT:R-HSA-162582", "REACT:R-HSA-3000170", "KEGG:hsa04350" ]
[ "Bladder cancer", "Disease", "Diseases of glycosylation", "ECM-receptor interaction", "Extracellular matrix organization", "Focal adhesion", "Hemostasis", "Integrin cell surface interactions", "Malaria", "Metabolism of proteins", "MicroRNAs in cancer", "O-linked glycosylation", "p53 signaling pathway", "Phagosome", "PI3K-Akt signaling pathway", "Platelet activation, signaling and aggregation", "Platelet degranulation", "Post-translational protein modification", "Proteoglycans in cancer", "Rap1 signaling pathway", "Signaling by PDGF", "Signal Transduction", "Syndecan interactions", "TGF-beta signaling pathway" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [] ]
Heme biosynthesis
Cholinergic synapse
Bladder cancer
Biotin transport and metabolism
2
29920-GP1
GP1
29920
PYCR2
[ "HLD10", "P5CR2", "P5C reductase 2" ]
[ "KEGG:hsa00330", "KEGG:hsa01230", "KEGG:hsa01100", "REACT:R-HSA-1430728", "REACT:R-HSA-71291" ]
[ "Arginine and proline metabolism", "Biosynthesis of amino acids", "Metabolic pathways", "Metabolism", "Metabolism of amino acids and derivatives" ]
[]
[ [], [], [], [], [] ]
Defective CHST6 causes MCDC1
Oocyte meiosis
Arginine and proline metabolism
Gap junction
2
7975-GP1
GP1
7975
MAFK
[ "MAF bZIP transcription factor K", "NFE2U", "P18", "transcription factor MafK" ]
[ "REACT:R-HSA-109582" ]
[ "Hemostasis" ]
[]
[ [] ]
Hemostasis
Activated TLR4 signalling
Ion channel transport
Biosynthesis of amino acids
0
4210-GP1
GP1
4210
MEFV
[ "FMF", "PAAND", "TRIM20", "pyrin", "Mediterranean fever", "marenostrin" ]
[ "REACT:R-HSA-168256", "REACT:R-HSA-622312", "REACT:R-HSA-168249", "KEGG:hsa04621", "REACT:R-HSA-844456" ]
[ "Immune System", "Inflammasomes", "Innate Immune System", "NOD-like receptor signaling pathway", "The NLRP3 inflammasome" ]
[]
[ [], [], [], [], [] ]
Chaperonin-mediated protein folding
NOD-like receptor signaling pathway
Phototransduction
Immune System
3
10868-GP1
GP1
10868
USP20
[ "ubiquitin specific peptidase 20", "LSFR3A", "VDU2", "hVDU2", "deubiquitinating enzyme 20", "ubiquitin thioesterase 20", "ubiquitin thiolesterase 20" ]
[ "REACT:R-HSA-5688426", "REACT:R-HSA-392499", "REACT:R-HSA-597592", "REACT:R-HSA-5689880" ]
[ "Deubiquitination", "Metabolism of proteins", "Post-translational protein modification", "Ub-specific processing proteases" ]
[]
[ [], [], [], [] ]
Deubiquitination
Activation of Matrix Metalloproteinases
Chemokine signaling pathway
NOD-like receptor signaling pathway
0
1393-GP1
GP1
1393
CRHBP
[ "corticotropin releasing hormone binding protein", "CRF-BP", "CRFBP", "CRF-binding protein" ]
[ "REACT:R-HSA-373080", "REACT:R-HSA-500792", "REACT:R-HSA-372790", "REACT:R-HSA-162582" ]
[ "Class B/2 (Secretin family receptors)", "GPCR ligand binding", "Signaling by GPCR", "Signal Transduction" ]
[]
[ [], [], [], [] ]
Class B/2 (Secretin family receptors)
Ribosome
Intra-Golgi traffic
Glycerophospholipid metabolism
0
11339-GP1
GP1
11339
OIP5
[ "Opa interacting protein 5", "5730547N13Rik", "CT86", "LINT-25", "MIS18B", "MIS18beta", "hMIS18beta", "protein Mis18-beta", "LAP2alpha interactor-25", "cancer/testis antigen 86", "opa-interacting protein 5" ]
[ "REACT:R-HSA-1640170", "REACT:R-HSA-73886", "REACT:R-HSA-774815" ]
[ "Cell Cycle", "Chromosome Maintenance", "Nucleosome assembly" ]
[]
[ [], [], [] ]
Cell adhesion molecules (CAMs)
Cell Cycle
DNA Double-Strand Break Repair
Chemokine receptors bind chemokines
1
11000-GP1
GP1
11000
SLC27A3
[ "solute carrier family 27 member 3", "ACSVL3", "FATP3", "VLCS-3", "solute carrier family 27 member 3", "long-chain fatty acid transport protein 3" ]
[ "KEGG:hsa04931", "REACT:R-HSA-1430728", "REACT:R-HSA-75109" ]
[ "Insulin resistance", "Metabolism", "Triglyceride Biosynthesis" ]
[]
[ [], [], [] ]
G alpha (q) signalling events
Intra-Golgi traffic
Insulin resistance
ER to Golgi Anterograde Transport
2
125919-GP1
GP1
125919
ZNF543
[ "zinc finger protein 543", "zinc finger protein 543" ]
[ "REACT:R-HSA-74160", "REACT:R-HSA-212436" ]
[ "Gene Expression", "Generic Transcription Pathway" ]
[]
[ [], [] ]
Gene Expression
Influenza A
Cul3-SPOP complex
Mitophagy - animal
0
259289-GP1
GP1
259289
TAS2R43
[ "taste 2 receptor member 43", "T2R43", "T2R52", "taste receptor type 2 member 43", "taste receptor type 2 member 52", "taste receptor, type 2, member 43" ]
[ "REACT:R-HSA-418594", "REACT:R-HSA-388396", "REACT:R-HSA-500792", "REACT:R-HSA-372790", "REACT:R-HSA-162582", "KEGG:hsa04742" ]
[ "G alpha (i) signalling events", "GPCR downstream signaling", "GPCR ligand binding", "Signaling by GPCR", "Signal Transduction", "Taste transduction" ]
[]
[ [], [], [], [], [], [] ]
Ether lipid metabolism
G alpha (i) signalling events
mRNA surveillance pathway
Amino acid transport across the plasma membrane
1
83852-GP1
GP1
83852
SETDB2
[ "C13orf4", "CLLD8", "CLLL8", "KMT1F", "SET domain bifurcated 2" ]
[ "REACT:R-HSA-3247509", "REACT:R-HSA-4839726", "KEGG:hsa00310" ]
[ "Chromatin modifying enzymes", "Chromatin organization", "Lysine degradation" ]
[]
[ [], [], [] ]
G alpha (12/13) signalling events
Chromatin modifying enzymes
G alpha (i) signalling events
Mitochondrial translation
1
55521-GP1
GP1
55521
TRIM36
[ "tripartite motif containing 36", "ANPH", "HAPRIN", "RBCC728", "RNF98", "RING finger protein 98", "tripartite motif protein 36", "tripartite motif-containing protein 36", "zinc-binding protein Rbcc728" ]
[ "REACT:R-HSA-1280218", "REACT:R-HSA-983169", "REACT:R-HSA-168256" ]
[ "Adaptive Immune System", "Class I MHC mediated antigen processing & presentation", "Immune System" ]
[]
[ [], [], [] ]
Rho GTPase cycle
Adaptive Immune System
G alpha (12/13) signalling events
Gap junction
1
3763-GP1
GP1
3763
KCNJ6
[ "BIR1", "GIRK-2", "GIRK2", "KATP-2", "KATP2", "KCNJ7", "KIR3.2", "KPLBS", "hiGIRK2", "potassium voltage-gated channel subfamily J member 6" ]
[ "REACT:R-HSA-991365", "KEGG:hsa04725", "KEGG:hsa04713", "KEGG:hsa04728", "KEGG:hsa04915", "REACT:R-HSA-977444", "KEGG:hsa04727", "REACT:R-HSA-977443", "REACT:R-HSA-1296059", "REACT:R-HSA-1296065", "KEGG:hsa05032", "REACT:R-HSA-112316", "KEGG:hsa04921", "REACT:R-HSA-1296071", "KEGG:hsa04723", "KEGG:hsa04726", "REACT:R-HSA-112315" ]
[ "Activation of GABAB receptors", "Cholinergic synapse", "Circadian entrainment", "Dopaminergic synapse", "Estrogen signaling pathway", "GABA B receptor activation", "GABAergic synapse", "GABA receptor activation", "G protein gated Potassium channels", "Inwardly rectifying K+ channels", "Morphine addiction", "Neuronal System", "Oxytocin signaling pathway", "Potassium Channels", "Retrograde endocannabinoid signaling", "Serotonergic synapse", "Transmission across Chemical Synapses" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [] ]
Influenza A
Alcoholism
ER to Golgi Anterograde Transport
Activation of GABAB receptors
3
10557-GP1
GP1
10557
RPP38
[ "ribonuclease P protein subunit p38", "RNaseP protein p38" ]
[ "REACT:R-HSA-74160", "KEGG:hsa03013", "REACT:R-HSA-72312", "REACT:R-HSA-72306", "REACT:R-HSA-6784531" ]
[ "Gene Expression", "RNA transport", "rRNA processing", "tRNA processing", "tRNA processing in the nucleus" ]
[]
[ [], [], [], [], [] ]
G alpha (12/13) signalling events
Intra-Golgi traffic
Gene Expression
Epstein-Barr virus infection
2
8407-GP1
GP1
8407
TAGLN2
[ "transgelin 2", "HA1756", "transgelin-2", "SM22-alpha homolog", "epididymis secretory sperm binding protein", "epididymis tissue protein Li 7e" ]
[ "REACT:R-HSA-109582", "REACT:R-HSA-76002", "REACT:R-HSA-114608" ]
[ "Hemostasis", "Platelet activation, signaling and aggregation", "Platelet degranulation" ]
[]
[ [], [], [] ]
PI3K-Akt signaling pathway
Adherens junction
Neuroactive ligand-receptor interaction
Hemostasis
3
6993-GP1
GP1
6993
DYNLT1
[ "CW-1", "TCTEL1", "TCTEX1", "tctex-1" ]
[ "REACT:R-HSA-168256", "REACT:R-HSA-168249", "REACT:R-HSA-6798695" ]
[ "Immune System", "Innate Immune System", "Neutrophil degranulation" ]
[]
[ [], [], [] ]
ABC-family proteins mediated transport
Immune System
IRE1alpha activates chaperones
Amino Acid conjugation
1
728369-GP1
GP1
728369
USP17L24
[ "USP17L25", "USP17L26", "USP17L27", "USP17L28", "USP17L29", "USP17L30", "deubiquitinating enzyme 17", "ubiquitin thioesterase 17" ]
[ "REACT:R-HSA-5688426", "REACT:R-HSA-392499", "REACT:R-HSA-597592", "REACT:R-HSA-5689880" ]
[ "Deubiquitination", "Metabolism of proteins", "Post-translational protein modification", "Ub-specific processing proteases" ]
[]
[ [], [], [], [] ]
G alpha (q) signalling events
AMPK signaling pathway
Activation of GABAB receptors
Deubiquitination
3
7416-GP1
GP1
7416
VDAC1
[ "voltage dependent anion channel 1", "PORIN", "voltage-dependent anion-selective channel protein 1", "outer mitochondrial membrane protein porin 1", "plasmalemmal porin", "porin 31HL", "porin 31HM", "sperm binding protein 1a" ]
[ "KEGG:hsa04020", "KEGG:hsa04022", "REACT:R-HSA-5688426", "KEGG:hsa05166", "KEGG:hsa05016", "KEGG:hsa05164", "REACT:R-HSA-392499", "REACT:R-HSA-1268020", "REACT:R-HSA-5205647", "KEGG:hsa04621", "KEGG:hsa05012", "REACT:R-HSA-5205685", "REACT:R-HSA-597592", "REACT:R-HSA-5689880" ]
[ "Calcium signaling pathway", "cGMP-PKG signaling pathway", "Deubiquitination", "HTLV-I infection", "Huntington's disease", "Influenza A", "Metabolism of proteins", "Mitochondrial protein import", "Mitophagy", "NOD-like receptor signaling pathway", "Parkinson's disease", "Pink/Parkin Mediated Mitophagy", "Post-translational protein modification", "Ub-specific processing proteases" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [], [] ]
Bladder cancer
Antimicrobial peptides
Tight junction
Calcium signaling pathway
3
91582-GP1
GP1
91582
RPS19BP1
[ "ribosomal protein S19 binding protein 1", "AROS", "active regulator of SIRT1", "RPS19-binding protein 1", "homolog of mouse S19 binding protein" ]
[ "REACT:R-HSA-2262752", "REACT:R-HSA-3371556", "REACT:R-HSA-3371453" ]
[ "Cellular responses to stress", "Cellular response to heat stress", "Regulation of HSF1-mediated heat shock response" ]
[]
[ [], [], [] ]
Cellular responses to stress
Heme biosynthesis
Acrosome Reaction
HRD1/SEL1 ERAD complex
0
55663-GP1
GP1
55663
ZNF446
[ "zinc finger protein 446", "ZKSCAN20", "ZSCAN30", "ZSCAN52", "zinc finger protein 446" ]
[ "REACT:R-HSA-74160", "REACT:R-HSA-212436" ]
[ "Gene Expression", "Generic Transcription Pathway" ]
[]
[ [], [] ]
Gene Expression
Antimicrobial peptides
Phototransduction
Muscle contraction
0
4916-GP1
GP1
4916
NTRK3
[ "GP145-TrkC", "TRKC", "gp145(trkC)", "NT-3 growth factor receptor", "ETV6-NTRK3 fusion", "tyrosine kinase receptor C" ]
[ "KEGG:hsa05230", "KEGG:hsa04722" ]
[ "Central carbon metabolism in cancer", "Neurotrophin signaling pathway" ]
[]
[ [], [] ]
Antimicrobial peptides
Spliceosome
Dectin-2 family
Central carbon metabolism in cancer
3
6845-GP1
GP1
6845
VAMP7
[ "vesicle associated membrane protein 7", "SYBL1", "TI-VAMP", "TIVAMP", "vesicle-associated membrane protein 7", "synaptobrevin-like 1", "synaptobrevin-like protein 1", "tetanus-insensitive VAMP" ]
[ "REACT:R-HSA-8856828", "REACT:R-HSA-432722", "REACT:R-HSA-432720", "REACT:R-HSA-199991", "KEGG:hsa04130", "REACT:R-HSA-5653656" ]
[ "Clathrin-mediated endocytosis", "Golgi Associated Vesicle Biogenesis", "Lysosome Vesicle Biogenesis", "Membrane Trafficking", "SNARE interactions in vesicular transport", "Vesicle-mediated transport" ]
[]
[ [], [], [], [], [], [] ]
Clathrin-mediated endocytosis
G alpha (s) signalling events
Mitophagy - animal
Bile secretion
0
56000-GP1
GP1
56000
NXF3
[ "nuclear RNA export factor 3", "nuclear RNA export factor 3", "TAP-like protein 3", "TAPL-3" ]
[ "KEGG:hsa05168", "KEGG:hsa05164", "KEGG:hsa03015", "KEGG:hsa03013" ]
[ "Herpes simplex infection", "Influenza A", "mRNA surveillance pathway", "RNA transport" ]
[]
[ [], [], [], [] ]
Biotin transport and metabolism
Herpes simplex infection
Amine ligand-binding receptors
Chylomicron-mediated lipid transport
1
10887-GP1
GP1
10887
PROKR1
[ "prokineticin receptor 1", "GPR73", "GPR73a", "PK-R1", "PKR1", "ZAQ", "prokineticin receptor 1", "G protein-coupled receptor 73", "G protein-coupled receptor ZAQ" ]
[ "REACT:R-HSA-416476", "REACT:R-HSA-388396", "REACT:R-HSA-500792", "REACT:R-HSA-375276", "REACT:R-HSA-372790", "REACT:R-HSA-162582" ]
[ "G alpha (q) signalling events", "GPCR downstream signaling", "GPCR ligand binding", "Peptide ligand-binding receptors", "Signaling by GPCR", "Signal Transduction" ]
[]
[ [], [], [], [], [], [] ]
Arginine biosynthesis
G alpha (q) signalling events
Ovarian steroidogenesis
Bile secretion
1
51191-GP1
GP1
51191
HERC5
[ "CEB1", "CEBP1", "cyclin-E-binding protein 1", "hect domain and RLD 5" ]
[ "REACT:R-HSA-1280218", "REACT:R-HSA-983169", "REACT:R-HSA-1280215", "REACT:R-HSA-168256", "REACT:R-HSA-168249", "REACT:R-HSA-913531", "REACT:R-HSA-1169408" ]
[ "Adaptive Immune System", "Class I MHC mediated antigen processing & presentation", "Cytokine Signaling in Immune system", "Immune System", "Innate Immune System", "Interferon Signaling", "ISG15 antiviral mechanism" ]
[]
[ [], [], [], [], [], [], [] ]
Ether lipid metabolism
Deubiquitination
Adaptive Immune System
Adherens junctions interactions
2
8625-GP1
GP1
8625
RFXANK
[ "regulatory factor X associated ankyrin containing protein", "ANKRA1", "BLS", "F14150_1", "RFX-B", "DNA-binding protein RFXANK", "RFX-Bdelta4", "ankyrin repeat family A protein 1", "regulatory factor X subunit B" ]
[ "KEGG:hsa04612", "KEGG:hsa05340", "KEGG:hsa05152" ]
[ "Antigen processing and presentation", "Primary immunodeficiency", "Tuberculosis" ]
[]
[ [], [], [] ]
Epstein-Barr virus infection
Defective CHST6 causes MCDC1
Antigen processing and presentation
G alpha (s) signalling events
2
29882-GP1
GP1
29882
ANAPC2
[ "anaphase promoting complex subunit 2", "anaphase-promoting complex subunit 2", "cyclosome subunit 2" ]
[ "REACT:R-HSA-1280218", "KEGG:hsa_M00389", "REACT:R-HSA-1640170", "KEGG:hsa04110", "REACT:R-HSA-69620", "REACT:R-HSA-69278", "REACT:R-HSA-2262752", "REACT:R-HSA-2559583", "REACT:R-HSA-983169", "KEGG:hsa05166", "REACT:R-HSA-168256", "REACT:R-HSA-68882", "REACT:R-HSA-2555396", "REACT:R-HSA-69618", "REACT:R-HSA-68886", "KEGG:hsa04114", "REACT:R-HSA-453276", "REACT:R-HSA-2467813", "KEGG:hsa04120" ]
[ "Adaptive Immune System", "APC/C complex", "Cell Cycle", "Cell cycle", "Cell Cycle Checkpoints", "Cell Cycle, Mitotic", "Cellular responses to stress", "Cellular Senescence", "Class I MHC mediated antigen processing & presentation", "HTLV-I infection", "Immune System", "Mitotic Anaphase", "Mitotic Metaphase and Anaphase", "Mitotic Spindle Checkpoint", "M Phase", "Oocyte meiosis", "Regulation of mitotic cell cycle", "Separation of Sister Chromatids", "Ubiquitin mediated proteolysis" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [] ]
Adaptive Immune System
Signaling by PTK6
HDL-mediated lipid transport
Gap junction
0
26285-GP1
GP1
26285
CLDN17
[ "claudin 17", "claudin-17" ]
[ "KEGG:hsa04514", "REACT:R-HSA-1500931", "REACT:R-HSA-421270", "REACT:R-HSA-446728", "KEGG:hsa05160", "KEGG:hsa04670", "KEGG:hsa04530", "REACT:R-HSA-420029" ]
[ "Cell adhesion molecules (CAMs)", "Cell-Cell communication", "Cell-cell junction organization", "Cell junction organization", "Hepatitis C", "Leukocyte transendothelial migration", "Tight junction", "Tight junction interactions" ]
[]
[ [], [], [], [], [], [], [], [] ]
Phototransduction
Cell adhesion molecules (CAMs)
Thyroid hormone synthesis
Linoleic acid (LA) metabolism
1
26740-GP1
GP1
26740
OR1J2
[ "HG152", "HSA5", "OR1J3", "OR1J5", "OR9-19", "OST044", "olfactory receptor 1J2", "HTPCRX15", "olfactory receptor 1J3", "olfactory receptor 1J5", "olfactory receptor OR9-19" ]
[ "REACT:R-HSA-388396", "REACT:R-HSA-381753", "KEGG:hsa04740", "REACT:R-HSA-372790", "REACT:R-HSA-162582" ]
[ "GPCR downstream signaling", "Olfactory Signaling Pathway", "Olfactory transduction", "Signaling by GPCR", "Signal Transduction" ]
[]
[ [], [], [], [], [] ]
African trypanosomiasis
Dorso-ventral axis formation
Neuronal System
GPCR downstream signaling
3
392309-GP1
GP1
392309
OR13J1
[ "OR9-2", "olfactory receptor 13J1", "olfactory receptor OR9-2" ]
[ "REACT:R-HSA-388396", "REACT:R-HSA-381753", "KEGG:hsa04740", "REACT:R-HSA-372790", "REACT:R-HSA-162582" ]
[ "GPCR downstream signaling", "Olfactory Signaling Pathway", "Olfactory transduction", "Signaling by GPCR", "Signal Transduction" ]
[]
[ [], [], [], [], [] ]
GPCR downstream signaling
Autophagy - animal
Acute myeloid leukemia
Neuroactive ligand-receptor interaction
0
9027-GP1
GP1
9027
NAT8
[ "ATase2", "CCNAT", "CML1", "GLA", "Hcml1", "TSC501", "TSC510", "N-acetyltransferase 8", "acetyltransferase 2", "camello-like protein 1", "kidney- and liver-specific gene product" ]
[ "REACT:R-HSA-977225", "KEGG:hsa00480", "REACT:R-HSA-392499" ]
[ "Amyloid fiber formation", "Glutathione metabolism", "Metabolism of proteins" ]
[]
[ [], [], [] ]
Amyloid fiber formation
Cul3-SPOP complex
RHO GTPase Effectors
Chemokine receptors bind chemokines
0
8793-GP1
GP1
8793
TNFRSF10D
[ "TNF receptor superfamily member 10d", "CD264", "DCR2", "TRAIL-R4", "TRAILR4", "TRUNDD", "TNF receptor-related receptor for TRAIL", "TRAIL receptor 4", "TRAIL receptor with a truncated death domain", "decoy receptor 2" ]
[ "KEGG:hsa04210", "REACT:R-HSA-202733", "KEGG:hsa04060", "REACT:R-HSA-74160", "REACT:R-HSA-212436", "REACT:R-HSA-109582", "KEGG:hsa05164", "KEGG:hsa05162", "KEGG:hsa04650", "REACT:R-HSA-3700989" ]
[ "Apoptosis", "Cell surface interactions at the vascular wall", "Cytokine-cytokine receptor interaction", "Gene Expression", "Generic Transcription Pathway", "Hemostasis", "Influenza A", "Measles", "Natural killer cell mediated cytotoxicity", "Transcriptional Regulation by TP53" ]
[]
[ [], [], [], [], [], [], [], [], [], [] ]
GPCR downstream signaling
Bile acid and bile salt metabolism
Acrosome Reaction
Apoptosis
3
5094-GP1
GP1
5094
PCBP2
[ "poly(rC) binding protein 2", "HNRNPE2", "HNRPE2", "hnRNP-E2", "poly(rC)-binding protein 2", "alpha-CP2", "epididymis secretory sperm binding protein", "hnRNP E2" ]
[ "KEGG:hsa04216", "REACT:R-HSA-74160", "REACT:R-HSA-168256", "REACT:R-HSA-168249", "REACT:R-HSA-72172", "REACT:R-HSA-72163" ]
[ "Ferroptosis", "Gene Expression", "Immune System", "Innate Immune System", "mRNA Splicing", "mRNA Splicing - Major Pathway" ]
[]
[ [], [], [], [], [], [] ]
G alpha (12/13) signalling events
Spliceosome
Ribosome
Ferroptosis
3
4720-GP1
GP1
4720
NDUFS2
[ "CI-49", "MC1DN6", "CI-49kD", "complex I 49kDa subunit" ]
[ "KEGG:hsa05010", "REACT:R-HSA-6799198", "KEGG:hsa05016", "KEGG:hsa01100", "REACT:R-HSA-1430728", "KEGG:hsa00190", "KEGG:hsa05012", "REACT:R-HSA-611105" ]
[ "Alzheimer's disease", "Complex I biogenesis", "Huntington's disease", "Metabolic pathways", "Metabolism", "Oxidative phosphorylation", "Parkinson's disease", "Respiratory electron transport" ]
[]
[ [], [], [], [], [], [], [], [] ]
Cell adhesion molecules (CAMs)
FGFR2 alternative splicing
Alzheimer's disease
Cap-dependent Translation Initiation
2
11173-GP1
GP1
11173
ADAMTS7
[ "ADAM-TS 7", "COMPase" ]
[ "REACT:R-HSA-1643685", "REACT:R-HSA-3781865", "REACT:R-HSA-392499", "REACT:R-HSA-5173105", "REACT:R-HSA-597592" ]
[ "Disease", "Diseases of glycosylation", "Metabolism of proteins", "O-linked glycosylation", "Post-translational protein modification" ]
[]
[ [], [], [], [], [] ]
Disease
Cell-Cell communication
HDL-mediated lipid transport
Oxytocin signaling pathway
0
55690-GP1
GP1
55690
PACS1
[ "MRD17", "SHMS", "cytosolic sorting protein PACS-1" ]
[ "REACT:R-HSA-1643685", "REACT:R-HSA-162906", "REACT:R-HSA-162909", "REACT:R-HSA-5663205" ]
[ "Disease", "HIV Infection", "Host Interactions of HIV factors", "Infectious disease" ]
[]
[ [], [], [], [] ]
G alpha (i) signalling events
Disease
Activation of the pre-replicative complex
Dectin-2 family
1
64333-GP1
GP1
64333
ARHGAP9
[ "Rho GTPase activating protein 9", "10C", "RGL1", "rho GTPase-activating protein 9" ]
[ "REACT:R-HSA-168256", "REACT:R-HSA-168249", "REACT:R-HSA-6798695", "REACT:R-HSA-194840", "REACT:R-HSA-194315", "REACT:R-HSA-162582" ]
[ "Immune System", "Innate Immune System", "Neutrophil degranulation", "Rho GTPase cycle", "Signaling by Rho GTPases", "Signal Transduction" ]
[]
[ [], [], [], [], [], [] ]
Butanoate metabolism
Immune System
Ca2+ activated K+ channels
RA biosynthesis pathway
1
161357-GP1
GP1
161357
MDGA2
[ "MAMDC1", "c14_5286", "MAM domain containing 1" ]
[ "REACT:R-HSA-392499", "REACT:R-HSA-597592" ]
[ "Metabolism of proteins", "Post-translational protein modification" ]
[]
[ [], [] ]
Leukocyte transendothelial migration
ABC-family proteins mediated transport
Metabolism of proteins
Cytokine-cytokine receptor interaction
2
5048-GP1
GP1
5048
PAFAH1B1
[ "LIS1", "LIS2", "MDCR", "MDS", "NudF", "lissencephaly 1 protein" ]
[ "REACT:R-HSA-8854518", "REACT:R-HSA-1640170", "REACT:R-HSA-69278", "REACT:R-HSA-380287", "REACT:R-HSA-5617833", "KEGG:hsa00565", "REACT:R-HSA-69275", "REACT:R-HSA-199991", "KEGG:hsa01100", "REACT:R-HSA-68882", "REACT:R-HSA-2555396", "REACT:R-HSA-68877", "REACT:R-HSA-68886", "REACT:R-HSA-1852241", "REACT:R-HSA-2500257", "REACT:R-HSA-195258", "REACT:R-HSA-5663220", "REACT:R-HSA-2467813", "REACT:R-HSA-194315", "REACT:R-HSA-162582", "REACT:R-HSA-5653656" ]
[ "AURKA Activation by TPX2", "Cell Cycle", "Cell Cycle, Mitotic", "Centrosome maturation", "Cilium Assembly", "Ether lipid metabolism", "G2/M Transition", "Membrane Trafficking", "Metabolic pathways", "Mitotic Anaphase", "Mitotic Metaphase and Anaphase", "Mitotic Prometaphase", "M Phase", "Organelle biogenesis and maintenance", "Resolution of Sister Chromatid Cohesion", "RHO GTPase Effectors", "RHO GTPases Activate Formins", "Separation of Sister Chromatids", "Signaling by Rho GTPases", "Signal Transduction", "Vesicle-mediated transport" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [] ]
AURKA Activation by TPX2
Amino sugar and nucleotide sugar metabolism
Breast cancer
Heme biosynthesis
0
3012-GP1
GP1
3012
H2AC8
[ "H2A clustered histone 8", "H2A.1", "H2A.2", "H2A/a", "H2AC4", "H2AFA", "HIST1H2AE", "H2A histone family, member A", "histone 1, H2ae", "histone H2A/a", "histone H2AE", "histone cluster 1 H2A family member e", "histone cluster 1, H2ae" ]
[ "REACT:R-HSA-5619507", "KEGG:hsa05034", "REACT:R-HSA-977225", "REACT:R-HSA-1640170", "REACT:R-HSA-69278", "REACT:R-HSA-2262752", "REACT:R-HSA-2559583", "REACT:R-HSA-3247509", "REACT:R-HSA-4839726", "REACT:R-HSA-73886", "REACT:R-HSA-5688426", "REACT:R-HSA-1266738", "REACT:R-HSA-5334118", "REACT:R-HSA-212165", "REACT:R-HSA-74160", "REACT:R-HSA-211000", "REACT:R-HSA-3214847", "REACT:R-HSA-3214815", "REACT:R-HSA-1500620", "REACT:R-HSA-912446", "REACT:R-HSA-1221632", "REACT:R-HSA-392499", "REACT:R-HSA-5689901", "REACT:R-HSA-68875", "REACT:R-HSA-68886", "REACT:R-HSA-427413", "REACT:R-HSA-774815", "REACT:R-HSA-171306", "REACT:R-HSA-597592", "REACT:R-HSA-212300", "REACT:R-HSA-195258", "REACT:R-HSA-73777", "REACT:R-HSA-73854", "REACT:R-HSA-73728", "REACT:R-HSA-73864", "REACT:R-HSA-194315", "REACT:R-HSA-195721", "REACT:R-HSA-162582", "KEGG:hsa05322", "REACT:R-HSA-201681", "REACT:R-HSA-157579", "REACT:R-HSA-5578749", "REACT:R-HSA-5689880", "REACT:R-HSA-5689603" ]
[ "Activation of HOX genes during differentiation", "Alcoholism", "Amyloid fiber formation", "Cell Cycle", "Cell Cycle, Mitotic", "Cellular responses to stress", "Cellular Senescence", "Chromatin modifying enzymes", "Chromatin organization", "Chromosome Maintenance", "Deubiquitination", "Developmental Biology", "DNA methylation", "Epigenetic regulation of gene expression", "Gene Expression", "Gene Silencing by RNA", "HATs acetylate histones", "HDACs deacetylate histones", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Metabolism of proteins", "Metalloprotease DUBs", "Mitotic Prophase", "M Phase", "NoRC negatively regulates rRNA expression", "Nucleosome assembly", "Packaging Of Telomere Ends", "Post-translational protein modification", "PRC2 methylates histones and DNA", "RHO GTPase Effectors", "RNA Polymerase I Chain Elongation", "RNA Polymerase I Promoter Clearance", "RNA Polymerase I Promoter Opening", "RNA Polymerase I Transcription", "Signaling by Rho GTPases", "Signaling by Wnt", "Signal Transduction", "Systemic lupus erythematosus", "TCF dependent signaling in response to WNT", "Telomere Maintenance", "Transcriptional regulation by small RNAs", "Ub-specific processing proteases", "UCH proteinases" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [] ]
Tight junction
Autophagy - animal
RNA transport
Activation of HOX genes during differentiation
3
1831-GP1
GP1
1831
TSC22D3
[ "TSC22 domain family member 3", "DIP", "DSIPI", "GILZ", "TSC-22R", "TSC22 domain family protein 3", "DSIP-immunoreactive peptide", "TSC-22 related protein", "TSC-22-like protein" ]
[ "REACT:R-HSA-983712", "REACT:R-HSA-2672351", "REACT:R-HSA-382551" ]
[ "Ion channel transport", "Stimuli-sensing channels", "Transmembrane transport of small molecules" ]
[]
[ [], [], [] ]
Alpha-defensins
Breast cancer
Ion channel transport
Cholinergic synapse
2
1138-GP1
GP1
1138
CHRNA5
[ "LNCR2" ]
[ "KEGG:hsa04080", "REACT:R-HSA-112316", "REACT:R-HSA-112315" ]
[ "Neuroactive ligand-receptor interaction", "Neuronal System", "Transmission across Chemical Synapses" ]
[]
[ [], [], [] ]
Calnexin/calreticulin cycle
Muscle contraction
Developmental Biology
Neuroactive ligand-receptor interaction
3
10612-GP1
GP1
10612
TRIM3
[ "tripartite motif containing 3", "BERP", "HAC1", "RNF22", "RNF97", "tripartite motif-containing protein 3", "RING finger protein 97", "brain expressed ring finger", "brain-expressed RING finger protein", "ring finger protein 22", "tripartite motif protein TRIM3" ]
[ "REACT:R-HSA-1280215", "REACT:R-HSA-168256", "REACT:R-HSA-877300", "REACT:R-HSA-913531" ]
[ "Cytokine Signaling in Immune system", "Immune System", "Interferon gamma signaling", "Interferon Signaling" ]
[]
[ [], [], [], [] ]
Cytokine Signaling in Immune system
Bladder cancer
Adherens junction
Breast cancer
0
92815-GP1
GP1
92815
H2AW
[ "H2A.W histone", "HIST3H2A", "histone H2A type 3", "histone 3, H2a", "histone cluster 3 H2A", "histone cluster 3, H2a" ]
[ "KEGG:hsa05034", "REACT:R-HSA-3247509", "REACT:R-HSA-4839726", "REACT:R-HSA-5688426", "REACT:R-HSA-3214847", "REACT:R-HSA-3214815", "REACT:R-HSA-392499", "REACT:R-HSA-5689901", "REACT:R-HSA-597592", "KEGG:hsa05322", "REACT:R-HSA-5689880", "REACT:R-HSA-5689603" ]
[ "Alcoholism", "Chromatin modifying enzymes", "Chromatin organization", "Deubiquitination", "HATs acetylate histones", "HDACs deacetylate histones", "Metabolism of proteins", "Metalloprotease DUBs", "Post-translational protein modification", "Systemic lupus erythematosus", "Ub-specific processing proteases", "UCH proteinases" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [] ]
Activation of GABAB receptors
Starch and sucrose metabolism
Amine ligand-binding receptors
Alcoholism
3
55958-GP1
GP1
55958
KLHL9
[ "kelch like family member 9", "kelch-like protein 9" ]
[ "REACT:R-HSA-1280218", "REACT:R-HSA-983169", "REACT:R-HSA-168256", "KEGG:hsa04120" ]
[ "Adaptive Immune System", "Class I MHC mediated antigen processing & presentation", "Immune System", "Ubiquitin mediated proteolysis" ]
[]
[ [], [], [], [] ]
Amoebiasis
Adaptive Immune System
Acrosome Reaction
Mineral absorption
1
27034-GP1
GP1
27034
ACAD8
[ "ARC42", "IBDH" ]
[ "REACT:R-HSA-70895", "KEGG:hsa01100", "REACT:R-HSA-1430728", "REACT:R-HSA-71291" ]
[ "Branched-chain amino acid catabolism", "Metabolic pathways", "Metabolism", "Metabolism of amino acids and derivatives" ]
[]
[ [], [], [], [] ]
Branched-chain amino acid catabolism
Alzheimer's disease
Intra-Golgi traffic
Amoebiasis
0
7094-GP1
GP1
7094
TLN1
[ "talin 1", "ILWEQ", "talin-1" ]
[ "REACT:R-HSA-170984", "REACT:R-HSA-422475", "REACT:R-HSA-1280215", "REACT:R-HSA-2172127", "REACT:R-HSA-2424491", "REACT:R-HSA-1266738", "REACT:R-HSA-1643685", "REACT:R-HSA-5663202", "REACT:R-HSA-186763", "REACT:R-HSA-2871796", "KEGG:hsa04510", "REACT:R-HSA-170968", "REACT:R-HSA-179812", "REACT:R-HSA-109582", "KEGG:hsa05166", "REACT:R-HSA-2428924", "REACT:R-HSA-168256", "REACT:R-HSA-168249", "REACT:R-HSA-74751", "REACT:R-HSA-354192", "REACT:R-HSA-451927", "REACT:R-HSA-912526", "REACT:R-HSA-381070", "REACT:R-HSA-112399", "REACT:R-HSA-5674135", "REACT:R-HSA-5684996", "REACT:R-HSA-5683057", "REACT:R-HSA-392499", "REACT:R-HSA-397014", "REACT:R-HSA-375165", "REACT:R-HSA-6802957", "KEGG:hsa04611", "REACT:R-HSA-76002", "REACT:R-HSA-76009", "REACT:R-HSA-114608", "REACT:R-HSA-169893", "REACT:R-HSA-5673001", "KEGG:hsa04015", "REACT:R-HSA-8853659", "REACT:R-HSA-373755", "REACT:R-HSA-180336", "REACT:R-HSA-6802952", "REACT:R-HSA-177929", "REACT:R-HSA-372790", "REACT:R-HSA-74752", "REACT:R-HSA-449147", "REACT:R-HSA-2586552", "REACT:R-HSA-6802946", "REACT:R-HSA-186797", "REACT:R-HSA-6802949", "REACT:R-HSA-1433557", "REACT:R-HSA-194138", "REACT:R-HSA-166520", "REACT:R-HSA-187687", "REACT:R-HSA-167044", "REACT:R-HSA-162582", "REACT:R-HSA-445355", "REACT:R-HSA-112412", "REACT:R-HSA-381119", "REACT:R-HSA-5218921" ]
[ "ARMS-mediated activation", "Axon guidance", "Cytokine Signaling in Immune system", "DAP12 interactions", "DAP12 signaling", "Developmental Biology", "Disease", "Diseases of signal transduction", "Downstream signal transduction", "FCERI mediated MAPK activation", "Focal adhesion", "Frs2-mediated activation", "GRB2 events in EGFR signaling", "Hemostasis", "HTLV-I infection", "IGF1R signaling cascade", "Immune System", "Innate Immune System", "Insulin receptor signalling cascade", "Integrin alphaIIb beta3 signaling", "Interleukin-2 signaling", "Interleukin receptor SHC signaling", "IRE1alpha activates chaperones", "IRS-mediated signalling", "MAP2K and MAPK activation", "MAPK1/MAPK3 signaling", "MAPK family signaling cascades", "Metabolism of proteins", "Muscle contraction", "NCAM signaling for neurite out-growth", "Oncogenic MAPK signaling", "Platelet activation", "Platelet activation, signaling and aggregation", "Platelet Aggregation (Plug Formation)", "Platelet degranulation", "Prolonged ERK activation events", "RAF/MAP kinase cascade", "Rap1 signaling pathway", "RET signaling", "Semaphorin interactions", "SHC1 events in EGFR signaling", "Signaling by BRAF and RAF fusions", "Signaling by EGFR", "Signaling by GPCR", "Signaling by Insulin receptor", "Signaling by Interleukins", "Signaling by Leptin", "Signaling by moderate kinase activity BRAF mutants", "Signaling by PDGF", "Signaling by RAS mutants", "Signaling by SCF-KIT", "Signaling by VEGF", "Signalling by NGF", "Signalling to ERKs", "Signalling to RAS", "Signal Transduction", "Smooth Muscle Contraction", "SOS-mediated signalling", "Unfolded Protein Response (UPR)", "VEGFR2 mediated cell proliferation" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [] ]
Salivary secretion
Amphetamine addiction
Breast cancer
ARMS-mediated activation
3
5336-GP1
GP1
5336
PLCG2
[ "phospholipase C gamma 2", "APLAID", "FCAS3", "PLC-IV", "PLC-gamma-2", "phospholipase C-IV" ]
[ "REACT:R-HSA-1280218", "KEGG:hsa04360", "KEGG:hsa04662", "KEGG:hsa04020", "REACT:R-HSA-2172127", "REACT:R-HSA-2424491", "REACT:R-HSA-5621480", "KEGG:hsa05169", "KEGG:hsa04012", "KEGG:hsa04664", "REACT:R-HSA-2871809", "REACT:R-HSA-2871796", "KEGG:hsa05214", "REACT:R-HSA-114604", "REACT:R-HSA-109582", "KEGG:hsa04066", "REACT:R-HSA-168256", "REACT:R-HSA-168249", "KEGG:hsa00562", "REACT:R-HSA-1483249", "KEGG:hsa04670", "KEGG:hsa01100", "REACT:R-HSA-1430728", "KEGG:hsa05206", "KEGG:hsa04650", "KEGG:hsa04722", "KEGG:hsa04064", "KEGG:hsa05223", "KEGG:hsa04380", "KEGG:hsa05200", "KEGG:hsa04072", "KEGG:hsa04611", "REACT:R-HSA-76002", "KEGG:hsa05205", "KEGG:hsa04014", "KEGG:hsa04919", "REACT:R-HSA-168898", "KEGG:hsa04370", "KEGG:hsa05110" ]
[ "Adaptive Immune System", "Axon guidance", "B cell receptor signaling pathway", "Calcium signaling pathway", "DAP12 interactions", "DAP12 signaling", "Dectin-2 family", "Epstein-Barr virus infection", "ErbB signaling pathway", "Fc epsilon RI signaling pathway", "FCERI mediated Ca+2 mobilization", "FCERI mediated MAPK activation", "Glioma", "GPVI-mediated activation cascade", "Hemostasis", "HIF-1 signaling pathway", "Immune System", "Innate Immune System", "Inositol phosphate metabolism", "Inositol phosphate metabolism", "Leukocyte transendothelial migration", "Metabolic pathways", "Metabolism", "MicroRNAs in cancer", "Natural killer cell mediated cytotoxicity", "Neurotrophin signaling pathway", "NF-kappa B signaling pathway", "Non-small cell lung cancer", "Osteoclast differentiation", "Pathways in cancer", "Phospholipase D signaling pathway", "Platelet activation", "Platelet activation, signaling and aggregation", "Proteoglycans in cancer", "Ras signaling pathway", "Thyroid hormone signaling pathway", "Toll-Like Receptors Cascades", "VEGF signaling pathway", "Vibrio cholerae infection" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [] ]
Pyrimidine metabolism
Dorso-ventral axis formation
Adaptive Immune System
Apoptosis
2
5584-GP1
GP1
5584
PRKCI
[ "protein kinase C iota", "DXS1179E", "PKCI", "nPKC-iota", "protein kinase C iota type", "PRKC-lambda/iota" ]
[ "REACT:R-HSA-1500931", "REACT:R-HSA-421270", "REACT:R-HSA-446728", "KEGG:hsa04144", "KEGG:hsa04390", "KEGG:hsa04910", "REACT:R-HSA-193704", "REACT:R-HSA-209543", "KEGG:hsa04611", "KEGG:hsa04015", "REACT:R-HSA-166520", "REACT:R-HSA-162582", "KEGG:hsa04530", "REACT:R-HSA-420029" ]
[ "Cell-Cell communication", "Cell-cell junction organization", "Cell junction organization", "Endocytosis", "Hippo signaling pathway", "Insulin signaling pathway", "p75 NTR receptor-mediated signalling", "p75NTR recruits signalling complexes", "Platelet activation", "Rap1 signaling pathway", "Signalling by NGF", "Signal Transduction", "Tight junction", "Tight junction interactions" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [], [] ]
Bile acid and bile salt metabolism
Amoebiasis
Pyrimidine metabolism
Cell-Cell communication
3
56888-GP1
GP1
56888
KCMF1
[ "potassium channel modulatory factor 1", "DEBT91", "FIGC", "PCMF", "ZZZ1", "FGF-induced in gastric cancer", "ZZ-type zinc finger-containing protein 1", "differentially expressed in branching tubulogenesis 91", "zinc finger, ZZ domain containing 1" ]
[ "REACT:R-HSA-168256", "REACT:R-HSA-168249", "REACT:R-HSA-6798695" ]
[ "Immune System", "Innate Immune System", "Neutrophil degranulation" ]
[]
[ [], [], [] ]
Immune System
Degradation of DVL
Cap binding complex
Ether lipid metabolism
0
2646-GP1
GP1
2646
GCKR
[ "glucokinase regulator", "FGQTL5", "GKRP", "glucokinase regulatory protein", "hexokinase 4 regulator" ]
[ "REACT:R-HSA-1643685", "REACT:R-HSA-5619115", "REACT:R-HSA-70153", "REACT:R-HSA-189200", "REACT:R-HSA-1430728", "REACT:R-HSA-71387", "REACT:R-HSA-425407", "REACT:R-HSA-5619102", "REACT:R-HSA-382551" ]
[ "Disease", "Disorders of transmembrane transporters", "Glucose transport", "Hexose transport", "Metabolism", "Metabolism of carbohydrates", "SLC-mediated transmembrane transport", "SLC transporter disorders", "Transmembrane transport of small molecules" ]
[]
[ [], [], [], [], [], [], [], [], [] ]
DAP12 interactions
Cap binding complex
Disease
Antimicrobial peptides
2
1268-GP1
GP1
1268
CNR1
[ "cannabinoid receptor 1", "CANN6", "CB-R", "CB1", "CB1A", "CB1K5", "CB1R", "cannabinoid receptor 1", "cannabinoid receptor 1 (brain)", "central cannabinoid receptor" ]
[ "REACT:R-HSA-418594", "REACT:R-HSA-388396", "REACT:R-HSA-500792", "KEGG:hsa04080", "KEGG:hsa04015", "KEGG:hsa04723", "REACT:R-HSA-372790", "REACT:R-HSA-162582" ]
[ "G alpha (i) signalling events", "GPCR downstream signaling", "GPCR ligand binding", "Neuroactive ligand-receptor interaction", "Rap1 signaling pathway", "Retrograde endocannabinoid signaling", "Signaling by GPCR", "Signal Transduction" ]
[]
[ [], [], [], [], [], [], [], [] ]
Salivary secretion
DNA methylation
Herpes simplex infection
G alpha (i) signalling events
3
22888-GP1
GP1
22888
UBOX5
[ "U-box domain containing 5", "RNF37", "UBCE7IP5", "UIP5", "hUIP5", "RING finger protein 37", "U-box domain-containing protein 5", "ubcM4-interacting protein 5" ]
[ "REACT:R-HSA-1280218", "REACT:R-HSA-983169", "REACT:R-HSA-168256", "KEGG:hsa04120" ]
[ "Adaptive Immune System", "Class I MHC mediated antigen processing & presentation", "Immune System", "Ubiquitin mediated proteolysis" ]
[]
[ [], [], [], [] ]
Activation of AMPA receptors
Gap junction
Tight junction
Adaptive Immune System
3
1159-GP1
GP1
1159
CKMT1B
[ "creatine kinase, mitochondrial 1B", "UMTCK", "creatine kinase U-type, mitochondrial", "U-MtCK", "acidic-type mitochondrial creatine kinase", "mia-CK", "ubiquitous mitochondrial creatine kinase" ]
[ "KEGG:hsa00330", "REACT:R-HSA-71288", "KEGG:hsa_M00047", "KEGG:hsa01100", "REACT:R-HSA-1430728", "REACT:R-HSA-71291", "REACT:R-HSA-351202" ]
[ "Arginine and proline metabolism", "Creatine metabolism", "Creatine pathway", "Metabolic pathways", "Metabolism", "Metabolism of amino acids and derivatives", "Metabolism of polyamines" ]
[]
[ [], [], [], [], [], [], [] ]
Breast cancer
Acute myeloid leukemia
Arginine and proline metabolism
Metabolism
2
89-GP1
GP1
89
ACTN3
[ "actinin alpha 3", "ACTN3D", "alpha-actinin-3", "F-actin cross-linking protein", "alpha-actinin skeletal muscle" ]
[ "REACT:R-HSA-1500931", "REACT:R-HSA-397014", "REACT:R-HSA-373753", "REACT:R-HSA-390522" ]
[ "Cell-Cell communication", "Muscle contraction", "Nephrin interactions", "Striated Muscle Contraction" ]
[]
[ [], [], [], [] ]
Basal transcription factors
RNA transport
Glycosphingolipid metabolism
Cell-Cell communication
3
6737-GP1
GP1
6737
TRIM21
[ "tripartite motif containing 21", "RNF81", "RO52", "Ro/SSA", "SSA", "SSA1", "52 kDa Ro protein", "RING finger protein 81", "Ro/SSA 52kDa", "SS-A", "Sicca syndrome antigen A", "ro(SS-A)", "sjoegren syndrome type A antigen", "tripartite motif-containing protein 21" ]
[ "REACT:R-HSA-1280218", "REACT:R-HSA-983169", "REACT:R-HSA-1280215", "REACT:R-HSA-1834949", "REACT:R-HSA-168256", "REACT:R-HSA-168249", "REACT:R-HSA-877300", "REACT:R-HSA-913531", "REACT:R-HSA-1834941", "KEGG:hsa05322" ]
[ "Adaptive Immune System", "Class I MHC mediated antigen processing & presentation", "Cytokine Signaling in Immune system", "Cytosolic sensors of pathogen-associated DNA", "Immune System", "Innate Immune System", "Interferon gamma signaling", "Interferon Signaling", "STING mediated induction of host immune responses", "Systemic lupus erythematosus" ]
[]
[ [], [], [], [], [], [], [], [], [], [] ]
Coenzyme A biosynthesis
Degradation of DVL
Metabolism
Adaptive Immune System
3
144715-GP1
GP1
144715
RAD9B
[ "RAD9 checkpoint clamp component B", "cell cycle checkpoint control protein RAD9B", "RAD9 homolog B" ]
[ "REACT:R-HSA-176187", "REACT:R-HSA-69620", "REACT:R-HSA-5693532", "REACT:R-HSA-73894", "REACT:R-HSA-69481", "REACT:R-HSA-69473", "REACT:R-HSA-74160", "REACT:R-HSA-212436", "REACT:R-HSA-5693579", "REACT:R-HSA-5693538", "REACT:R-HSA-5693607", "REACT:R-HSA-5633007", "REACT:R-HSA-3700989" ]
[ "Activation of ATR in response to replication stress", "Cell Cycle Checkpoints", "DNA Double-Strand Break Repair", "DNA Repair", "G2/M Checkpoints", "G2/M DNA damage checkpoint", "Gene Expression", "Generic Transcription Pathway", "Homologous DNA Pairing and Strand Exchange", "Homology Directed Repair", "Processing of DNA double-strand break ends", "Regulation of TP53 Activity", "Transcriptional Regulation by TP53" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [] ]
Activation of ATR in response to replication stress
Ribosome
Mitophagy - animal
Amphetamine addiction
0
5957-GP1
GP1
5957
RCVRN
[ "recoverin", "RCV1", "recoverin", "cancer associated retinopathy antigen", "cancer-associated retinopathy protein" ]
[ "KEGG:hsa04744", "REACT:R-HSA-162582", "REACT:R-HSA-2514856", "REACT:R-HSA-2187338" ]
[ "Phototransduction", "Signal Transduction", "The phototransduction cascade", "Visual phototransduction" ]
[]
[ [], [], [], [] ]
Activation of GABAB receptors
Membrane Trafficking
G alpha (q) signalling events
Phototransduction
3
1742-GP1
GP1
1742
DLG4
[ "MRD62", "PSD95", "SAP-90", "SAP90", "disks large homolog 4", "Tax interaction protein 15", "discs large homolog 4", "post-synaptic density protein 95", "synapse-associated protein 90" ]
[ "REACT:R-HSA-170984", "REACT:R-HSA-422475", "KEGG:hsa05030", "REACT:R-HSA-1280215", "REACT:R-HSA-2172127", "REACT:R-HSA-2424491", "REACT:R-HSA-1266738", "REACT:R-HSA-186763", "REACT:R-HSA-2871796", "REACT:R-HSA-170968", "KEGG:hsa04724", "REACT:R-HSA-179812", "KEGG:hsa04390", "KEGG:hsa05016", "REACT:R-HSA-2428924", "REACT:R-HSA-168256", "REACT:R-HSA-168249", "REACT:R-HSA-74751", "REACT:R-HSA-451927", "REACT:R-HSA-912526", "REACT:R-HSA-451306", "REACT:R-HSA-112399", "REACT:R-HSA-373760", "REACT:R-HSA-5682910", "REACT:R-HSA-5684996", "REACT:R-HSA-5683057", "REACT:R-HSA-375165", "REACT:R-HSA-112316", "REACT:R-HSA-447038", "REACT:R-HSA-438064", "REACT:R-HSA-169893", "REACT:R-HSA-6794362", "REACT:R-HSA-5673001", "REACT:R-HSA-8853659", "REACT:R-HSA-195258", "REACT:R-HSA-5625900", "REACT:R-HSA-8849932", "REACT:R-HSA-180336", "REACT:R-HSA-177929", "REACT:R-HSA-372790", "REACT:R-HSA-74752", "REACT:R-HSA-449147", "REACT:R-HSA-2586552", "REACT:R-HSA-186797", "REACT:R-HSA-194315", "REACT:R-HSA-1433557", "REACT:R-HSA-194138", "REACT:R-HSA-166520", "REACT:R-HSA-187687", "REACT:R-HSA-167044", "REACT:R-HSA-162582", "REACT:R-HSA-112412", "REACT:R-HSA-399719", "REACT:R-HSA-112315", "REACT:R-HSA-5218921" ]
[ "ARMS-mediated activation", "Axon guidance", "Cocaine addiction", "Cytokine Signaling in Immune system", "DAP12 interactions", "DAP12 signaling", "Developmental Biology", "Downstream signal transduction", "FCERI mediated MAPK activation", "Frs2-mediated activation", "Glutamatergic synapse", "GRB2 events in EGFR signaling", "Hippo signaling pathway", "Huntington's disease", "IGF1R signaling cascade", "Immune System", "Innate Immune System", "Insulin receptor signalling cascade", "Interleukin-2 signaling", "Interleukin receptor SHC signaling", "Ionotropic activity of Kainate Receptors", "IRS-mediated signalling", "L1CAM interactions", "LGI-ADAM interactions", "MAPK1/MAPK3 signaling", "MAPK family signaling cascades", "NCAM signaling for neurite out-growth", "Neuronal System", "NrCAM interactions", "Post NMDA receptor activation events", "Prolonged ERK activation events", "Protein-protein interactions at synapses", "RAF/MAP kinase cascade", "RET signaling", "RHO GTPase Effectors", "RHO GTPases activate CIT", "SALM protein interactions at the synapses", "SHC1 events in EGFR signaling", "Signaling by EGFR", "Signaling by GPCR", "Signaling by Insulin receptor", "Signaling by Interleukins", "Signaling by Leptin", "Signaling by PDGF", "Signaling by Rho GTPases", "Signaling by SCF-KIT", "Signaling by VEGF", "Signalling by NGF", "Signalling to ERKs", "Signalling to RAS", "Signal Transduction", "SOS-mediated signalling", "Trafficking of AMPA receptors", "Transmission across Chemical Synapses", "VEGFR2 mediated cell proliferation" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [] ]
Spliceosome
Acrosome Reaction
ARMS-mediated activation
Muscle contraction
2
84320-GP1
GP1
84320
ACBD6
[ "acyl-CoA binding domain containing 6" ]
[ "REACT:R-HSA-1430728", "REACT:R-HSA-75109" ]
[ "Metabolism", "Triglyceride Biosynthesis" ]
[]
[ [], [] ]
Metabolism
Budding and maturation of HIV virion
Alzheimer's disease
Oxytocin signaling pathway
0
5287-GP1
GP1
5287
PIK3C2B
[ "C2-PI3K", "PI3K-C2-beta", "PI3K-C2beta", "PTDINS-3-kinase C2 beta" ]
[ "KEGG:hsa00562", "KEGG:hsa01100", "REACT:R-HSA-1430728", "REACT:R-HSA-1483257", "REACT:R-HSA-1483255" ]
[ "Inositol phosphate metabolism", "Metabolic pathways", "Metabolism", "Phospholipid metabolism", "PI Metabolism" ]
[]
[ [], [], [], [], [] ]
Developmental Biology
ABC transporters
Inositol phosphate metabolism
Cilium Assembly
2
2177-GP1
GP1
2177
FANCD2
[ "FA complementation group D2", "FA-D2", "FA4", "FACD", "FAD", "FAD2", "Fanconi anemia group D2 protein", "Fanconi anemia complementation group D2" ]
[ "REACT:R-HSA-73894", "KEGG:hsa03460", "REACT:R-HSA-6783310", "REACT:R-HSA-74160", "REACT:R-HSA-212436", "REACT:R-HSA-3700989" ]
[ "DNA Repair", "Fanconi anemia pathway", "Fanconi Anemia Pathway", "Gene Expression", "Generic Transcription Pathway", "Transcriptional Regulation by TP53" ]
[]
[ [], [], [], [], [], [] ]
RHO GTPase Effectors
G alpha (q) signalling events
DNA Repair
G alpha (s) signalling events
2
22948-GP1
GP1
22948
CCT5
[ "chaperonin containing TCP1 subunit 5", "CCT-epsilon", "CCTE", "HEL-S-69", "PNAS-102", "TCP-1-epsilon", "T-complex protein 1 subunit epsilon", "epididymis secretory protein Li 69" ]
[ "REACT:R-HSA-5620920", "REACT:R-HSA-390466", "REACT:R-HSA-5617833", "REACT:R-HSA-392499", "REACT:R-HSA-1852241", "REACT:R-HSA-391251" ]
[ "Cargo trafficking to the periciliary membrane", "Chaperonin-mediated protein folding", "Cilium Assembly", "Metabolism of proteins", "Organelle biogenesis and maintenance", "Protein folding" ]
[]
[ [], [], [], [], [], [] ]
Metabolism of proteins
DNA methylation
Ca2+ activated K+ channels
Cargo trafficking to the periciliary membrane
3
56616-GP1
GP1
56616
DIABLO
[ "diablo IAP-binding mitochondrial protein", "DFNA64", "SMAC", "diablo homolog, mitochondrial", "diablo-like protein", "direct IAP-binding protein with low pI" ]
[ "KEGG:hsa04210", "REACT:R-HSA-109581", "KEGG:hsa04215", "REACT:R-HSA-111471", "REACT:R-HSA-109606", "REACT:R-HSA-5357801", "REACT:R-HSA-111463", "REACT:R-HSA-111469" ]
[ "Apoptosis", "Apoptosis", "Apoptosis - multiple species", "Apoptotic factor-mediated response", "Intrinsic Pathway for Apoptosis", "Programmed Cell Death", "SMAC binds to IAPs", "SMAC-mediated apoptotic response" ]
[]
[ [], [], [], [], [], [], [], [] ]
Ca2+ activated K+ channels
Mitophagy - animal
Apoptosis
Metabolism of proteins
2
56994-GP1
GP1
56994
CHPT1
[ "CPT", "CPT1", "AAPT1-like protein", "hCPT1" ]
[ "KEGG:hsa05231", "KEGG:hsa00565", "KEGG:hsa00564", "KEGG:hsa01100", "REACT:R-HSA-1430728", "REACT:R-HSA-1483257", "KEGG:hsa00440", "REACT:R-HSA-1483191" ]
[ "Choline metabolism in cancer", "Ether lipid metabolism", "Glycerophospholipid metabolism", "Metabolic pathways", "Metabolism", "Phospholipid metabolism", "Phosphonate and phosphinate metabolism", "Synthesis of PC" ]
[]
[ [], [], [], [], [], [], [], [] ]
Choline metabolism in cancer
Gap junction
ABC-family proteins mediated transport
Influenza A
0
54751-GP1
GP1
54751
FBLIM1
[ "filamin binding LIM protein 1", "CAL", "FBLP-1", "FBLP1", "filamin-binding LIM protein 1", "CSX-associated LIM", "MIG2-interacting protein", "migfilin", "mitogen-inducible 2 interacting protein" ]
[ "REACT:R-HSA-1500931", "REACT:R-HSA-446353", "REACT:R-HSA-446728" ]
[ "Cell-Cell communication", "Cell-extracellular matrix interactions", "Cell junction organization" ]
[]
[ [], [], [] ]
Complex I biogenesis
Cell-Cell communication
Arginine biosynthesis
Chemokine receptors bind chemokines
1
54863-GP1
GP1
54863
TOR4A
[ "torsin family 4 member A", "C9orf167", "torsin-4A", "torsin family protein C9orf167" ]
[ "REACT:R-HSA-109582", "REACT:R-HSA-76002", "REACT:R-HSA-114608" ]
[ "Hemostasis", "Platelet activation, signaling and aggregation", "Platelet degranulation" ]
[]
[ [], [], [] ]
Cilium Assembly
Antimicrobial peptides
Hemostasis
Cap binding complex
2