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stringlengths
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3
100169756-GP1
GP1
100169756
RNA5S5
[ "RNA, 5S ribosomal 5", "RN5S5", "5S rRNA 5" ]
[ "KEGG:hsa03010" ]
[ "Ribosome" ]
[]
[ [] ]
Insulin processing
African trypanosomiasis
Ribosome
Complement and coagulation cascades
2
738-GP1
GP1
738
VPS51
[ "VPS51 subunit of GARP complex", "ANG2", "ANG3", "C11orf2", "C11orf3", "FFR", "PCH13", "VPS51, GARP complex subunit", "another new gene 2 protein", "protein fat-free homolog", "vacuolar protein sorting 51 homolog" ]
[ "REACT:R-HSA-199991", "REACT:R-HSA-5653656" ]
[ "Membrane Trafficking", "Vesicle-mediated transport" ]
[]
[ [], [] ]
Membrane Trafficking
G alpha (i) signalling events
Hippo signaling
Dectin-2 family
0
5279-GP1
GP1
5279
PIGC
[ "GPI2", "GPIBD16", "MRT62" ]
[ "KEGG:hsa01100", "REACT:R-HSA-392499", "REACT:R-HSA-597592" ]
[ "Metabolic pathways", "Metabolism of proteins", "Post-translational protein modification" ]
[]
[ [], [], [] ]
Rho GTPase cycle
Metabolic pathways
G alpha (q) signalling events
Gap junction
1
29925-GP1
GP1
29925
GMPPB
[ "LGMDR19", "MDDGA14", "MDDGB14", "MDDGC14" ]
[ "KEGG:hsa00520", "KEGG:hsa00051", "KEGG:hsa01100", "REACT:R-HSA-392499", "REACT:R-HSA-597592", "REACT:R-HSA-446205" ]
[ "Amino sugar and nucleotide sugar metabolism", "Fructose and mannose metabolism", "Metabolic pathways", "Metabolism of proteins", "Post-translational protein modification", "Synthesis of GDP-mannose" ]
[]
[ [], [], [], [], [], [] ]
Neuronal System
Amino sugar and nucleotide sugar metabolism
Herpes simplex infection
Fertilization
1
1453-GP1
GP1
1453
CSNK1D
[ "casein kinase 1 delta", "ASPS", "CKI-delta", "CKId", "CKIdelta", "FASPS2", "HCKID", "casein kinase I isoform delta", "casein kinase I", "tau-protein kinase CSNK1D" ]
[ "REACT:R-HSA-8854518", "REACT:R-HSA-1640170", "REACT:R-HSA-69278", "REACT:R-HSA-380287", "REACT:R-HSA-5617833", "REACT:R-HSA-400253", "KEGG:hsa04710", "REACT:R-HSA-199977", "REACT:R-HSA-69275", "KEGG:hsa04540", "REACT:R-HSA-74160", "KEGG:hsa04340", "KEGG:hsa04390", "REACT:R-HSA-199991", "REACT:R-HSA-392499", "REACT:R-HSA-1852241", "REACT:R-HSA-597592", "REACT:R-HSA-72312", "REACT:R-HSA-948021", "REACT:R-HSA-5653656" ]
[ "AURKA Activation by TPX2", "Cell Cycle", "Cell Cycle, Mitotic", "Centrosome maturation", "Cilium Assembly", "Circadian Clock", "Circadian rhythm", "ER to Golgi Anterograde Transport", "G2/M Transition", "Gap junction", "Gene Expression", "Hedgehog signaling pathway", "Hippo signaling pathway", "Membrane Trafficking", "Metabolism of proteins", "Organelle biogenesis and maintenance", "Post-translational protein modification", "rRNA processing", "Transport to the Golgi and subsequent modification", "Vesicle-mediated transport" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [] ]
Influenza A
AURKA Activation by TPX2
Bladder cancer
Fertilization
1
6005-GP1
GP1
6005
RHAG
[ "Rh associated glycoprotein", "CD241", "OHS", "OHST", "RH2", "RH50A", "RHNR", "Rh50", "Rh50GP", "SLC42A1", "ammonium transporter Rh type A", "Rh 50 glycoprotein", "mutant Rh associated glycoprotein", "rh type A glycoprotein", "rhesus blood group-associated ammonia channel" ]
[ "REACT:R-HSA-1430728", "REACT:R-HSA-425407", "REACT:R-HSA-382551" ]
[ "Metabolism", "SLC-mediated transmembrane transport", "Transmembrane transport of small molecules" ]
[]
[ [], [], [] ]
DAP12 interactions
Metabolism
Basal cell carcinoma
Endocytosis
1
28956-GP1
GP1
28956
LAMTOR2
[ "ENDAP", "HSPC003", "MAPBPIP", "MAPKSP1AP", "ROBLD3", "Ragulator2", "p14", "ragulator complex protein LAMTOR2", "MAPBP-interacting protein", "MAPKSP1 adaptor protein", "endosomal adaptor protein p14", "roadblock domain containing 3", "roadblock domain-containing protein 3" ]
[ "REACT:R-HSA-170984", "REACT:R-HSA-422475", "REACT:R-HSA-2262752", "REACT:R-HSA-1280215", "REACT:R-HSA-2172127", "REACT:R-HSA-2424491", "REACT:R-HSA-1266738", "REACT:R-HSA-186763", "REACT:R-HSA-2871796", "REACT:R-HSA-170968", "REACT:R-HSA-74160", "REACT:R-HSA-212436", "REACT:R-HSA-179812", "REACT:R-HSA-2428924", "REACT:R-HSA-168256", "REACT:R-HSA-168249", "REACT:R-HSA-74751", "REACT:R-HSA-451927", "REACT:R-HSA-912526", "REACT:R-HSA-112399", "REACT:R-HSA-1632852", "REACT:R-HSA-5674135", "REACT:R-HSA-5684996", "REACT:R-HSA-5683057", "REACT:R-HSA-166208", "KEGG:hsa04150", "REACT:R-HSA-165159", "REACT:R-HSA-375165", "REACT:R-HSA-6798695", "REACT:R-HSA-109704", "REACT:R-HSA-109703", "REACT:R-HSA-169893", "REACT:R-HSA-5673001", "REACT:R-HSA-8853659", "REACT:R-HSA-180336", "REACT:R-HSA-177929", "REACT:R-HSA-372790", "REACT:R-HSA-74752", "REACT:R-HSA-449147", "REACT:R-HSA-2586552", "REACT:R-HSA-186797", "REACT:R-HSA-1433557", "REACT:R-HSA-194138", "REACT:R-HSA-166520", "REACT:R-HSA-187687", "REACT:R-HSA-167044", "REACT:R-HSA-162582", "REACT:R-HSA-112412", "REACT:R-HSA-5628897", "REACT:R-HSA-3700989", "REACT:R-HSA-5218921" ]
[ "ARMS-mediated activation", "Axon guidance", "Cellular responses to stress", "Cytokine Signaling in Immune system", "DAP12 interactions", "DAP12 signaling", "Developmental Biology", "Downstream signal transduction", "FCERI mediated MAPK activation", "Frs2-mediated activation", "Gene Expression", "Generic Transcription Pathway", "GRB2 events in EGFR signaling", "IGF1R signaling cascade", "Immune System", "Innate Immune System", "Insulin receptor signalling cascade", "Interleukin-2 signaling", "Interleukin receptor SHC signaling", "IRS-mediated signalling", "Macroautophagy", "MAP2K and MAPK activation", "MAPK1/MAPK3 signaling", "MAPK family signaling cascades", "mTORC1-mediated signalling", "mTOR signaling pathway", "mTOR signalling", "NCAM signaling for neurite out-growth", "Neutrophil degranulation", "PI3K Cascade", "PKB-mediated events", "Prolonged ERK activation events", "RAF/MAP kinase cascade", "RET signaling", "SHC1 events in EGFR signaling", "Signaling by EGFR", "Signaling by GPCR", "Signaling by Insulin receptor", "Signaling by Interleukins", "Signaling by Leptin", "Signaling by PDGF", "Signaling by SCF-KIT", "Signaling by VEGF", "Signalling by NGF", "Signalling to ERKs", "Signalling to RAS", "Signal Transduction", "SOS-mediated signalling", "TP53 Regulates Metabolic Genes", "Transcriptional Regulation by TP53", "VEGFR2 mediated cell proliferation" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [] ]
Antimicrobial peptides
Butanoate metabolism
ARMS-mediated activation
Oocyte meiosis
2
8427-GP1
GP1
8427
ZNF282
[ "zinc finger protein 282", "HUB1", "zinc finger protein 282", "HUB-1" ]
[ "REACT:R-HSA-74160", "REACT:R-HSA-212436" ]
[ "Gene Expression", "Generic Transcription Pathway" ]
[]
[ [], [] ]
Gene Expression
Amoebiasis
ABC-family proteins mediated transport
Neuroactive ligand-receptor interaction
0
57403-GP1
GP1
57403
RAB22A
[ "ras-related protein Rab-22A", "GTP-binding protein RAB22A" ]
[ "KEGG:hsa04144", "REACT:R-HSA-392499", "REACT:R-HSA-597592", "REACT:R-HSA-8873719" ]
[ "Endocytosis", "Metabolism of proteins", "Post-translational protein modification", "RAB geranylgeranylation" ]
[]
[ [], [], [], [] ]
Endocytosis
Muscle contraction
Amphetamine addiction
RNA transport
0
9448-GP1
GP1
9448
MAP4K4
[ "mitogen-activated protein kinase kinase kinase kinase 4", "FLH21957", "HEL-S-31", "HGK", "MEKKK4", "NIK", "mitogen-activated protein kinase kinase kinase kinase 4", "MAPK/ERK kinase kinase kinase 4", "MEK kinase kinase 4", "Ste20 group protein kinase HGK", "epididymis secretory protein Li 31", "nck-interacting kinase" ]
[ "REACT:R-HSA-2262752", "REACT:R-HSA-2559583", "KEGG:hsa04010" ]
[ "Cellular responses to stress", "Cellular Senescence", "MAPK signaling pathway" ]
[]
[ [], [], [] ]
Mitochondrial translation
Breast cancer
Cellular responses to stress
Alcoholism
2
10550-GP1
GP1
10550
ARL6IP5
[ "DERP11", "GTRAP3-18", "HSPC127", "JWA", "PRAF3", "Yip6b", "addicsin", "hp22", "jmx", "PRA1 family protein 3", "ARL-6-interacting protein 5", "JM5", "PRA1 domain family 3", "aip-5", "dermal papilla derived protein 11", "prenylated Rab acceptor protein 2", "protein JWa", "putative MAPK activating protein PM27" ]
[ "REACT:R-HSA-112316", "REACT:R-HSA-112310", "REACT:R-HSA-112315" ]
[ "Neuronal System", "Neurotransmitter Release Cycle", "Transmission across Chemical Synapses" ]
[]
[ [], [], [] ]
eNOS activation and regulation
Mitophagy - animal
Neuronal System
Antigen processing and presentation
2
100293534-GP1
GP1
100293534
C4B_2
[ "complement C4-B-like" ]
[ "REACT:R-HSA-174577", "REACT:R-HSA-166658", "REACT:R-HSA-168256", "REACT:R-HSA-166663", "REACT:R-HSA-168249", "REACT:R-HSA-977606" ]
[ "Activation of C3 and C5", "Complement cascade", "Immune System", "Initial triggering of complement", "Innate Immune System", "Regulation of Complement cascade" ]
[]
[ [], [], [], [], [], [] ]
Activation of C3 and C5
Cilium Assembly
Dectin-2 family
ER to Golgi Anterograde Transport
0
59345-GP1
GP1
59345
GNB4
[ "G protein subunit beta 4", "CMTD1F", "G protein beta-4 subunit", "transducin beta chain 4" ]
[ "KEGG:hsa05034", "KEGG:hsa04371", "REACT:R-HSA-445717", "REACT:R-HSA-3858494", "REACT:R-HSA-4086398", "REACT:R-HSA-390466", "KEGG:hsa04062", "KEGG:hsa04725", "KEGG:hsa04713", "REACT:R-HSA-373080", "KEGG:hsa04728", "KEGG:hsa04727", "REACT:R-HSA-416482", "REACT:R-HSA-418594", "REACT:R-HSA-416476", "REACT:R-HSA-418555", "REACT:R-HSA-418597", "REACT:R-HSA-163359", "REACT:R-HSA-420092", "KEGG:hsa04724", "REACT:R-HSA-388396", "REACT:R-HSA-500792", "REACT:R-HSA-202040", "REACT:R-HSA-109582", "REACT:R-HSA-163685", "REACT:R-HSA-1430728", "REACT:R-HSA-392499", "KEGG:hsa05032", "REACT:R-HSA-112316", "REACT:R-HSA-111885", "KEGG:hsa05200", "KEGG:hsa04151", "REACT:R-HSA-76002", "REACT:R-HSA-418346", "REACT:R-HSA-500657", "REACT:R-HSA-391251", "KEGG:hsa04014", "REACT:R-HSA-422356", "KEGG:hsa04723", "KEGG:hsa04726", "REACT:R-HSA-392518", "REACT:R-HSA-372790", "REACT:R-HSA-195721", "REACT:R-HSA-162582", "REACT:R-HSA-428930", "REACT:R-HSA-382551", "REACT:R-HSA-112315" ]
[ "Alcoholism", "Apelin signaling pathway", "Aquaporin-mediated transport", "Beta-catenin independent WNT signaling", "Ca2+ pathway", "Chaperonin-mediated protein folding", "Chemokine signaling pathway", "Cholinergic synapse", "Circadian entrainment", "Class B/2 (Secretin family receptors)", "Dopaminergic synapse", "GABAergic synapse", "G alpha (12/13) signalling events", "G alpha (i) signalling events", "G alpha (q) signalling events", "G alpha (s) signalling events", "G alpha (z) signalling events", "Glucagon signaling in metabolic regulation", "Glucagon-type ligand receptors", "Glutamatergic synapse", "GPCR downstream signaling", "GPCR ligand binding", "G-protein activation", "Hemostasis", "Integration of energy metabolism", "Metabolism", "Metabolism of proteins", "Morphine addiction", "Neuronal System", "Opioid Signalling", "Pathways in cancer", "PI3K-Akt signaling pathway", "Platelet activation, signaling and aggregation", "Platelet homeostasis", "Presynaptic function of Kainate receptors", "Protein folding", "Ras signaling pathway", "Regulation of insulin secretion", "Retrograde endocannabinoid signaling", "Serotonergic synapse", "Signal amplification", "Signaling by GPCR", "Signaling by Wnt", "Signal Transduction", "Thromboxane signalling through TP receptor", "Transmembrane transport of small molecules", "Transmission across Chemical Synapses" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [] ]
Neuroactive ligand-receptor interaction
Intra-Golgi traffic
Alcoholism
Cell surface interactions at the vascular wall
2
2831-GP1
GP1
2831
NPBWR1
[ "neuropeptides B and W receptor 1", "GPR7", "G-protein coupled receptor 7", "neuropeptide B/W receptor 1", "neuropeptides B/W receptor 1" ]
[ "REACT:R-HSA-418594", "REACT:R-HSA-388396", "REACT:R-HSA-500792", "KEGG:hsa04080", "REACT:R-HSA-375276", "REACT:R-HSA-372790", "REACT:R-HSA-162582" ]
[ "G alpha (i) signalling events", "GPCR downstream signaling", "GPCR ligand binding", "Neuroactive ligand-receptor interaction", "Peptide ligand-binding receptors", "Signaling by GPCR", "Signal Transduction" ]
[]
[ [], [], [], [], [], [], [] ]
MAPK signaling pathway
Cell adhesion molecules (CAMs)
Insulin processing
G alpha (i) signalling events
3
85358-GP1
GP1
85358
SHANK3
[ "SH3 and multiple ankyrin repeat domains 3", "DEL22q13.3", "PROSAP2", "PSAP2", "SCZD15", "SPANK-2", "proline rich synapse associated protein 2", "shank postsynaptic density protein", "shank3 postsynaptic density protein" ]
[ "REACT:R-HSA-422475", "REACT:R-HSA-1266738", "KEGG:hsa04724", "REACT:R-HSA-112316", "REACT:R-HSA-6794362", "REACT:R-HSA-8853659" ]
[ "Axon guidance", "Developmental Biology", "Glutamatergic synapse", "Neuronal System", "Protein-protein interactions at synapses", "RET signaling" ]
[]
[ [], [], [], [], [], [] ]
Axon guidance
Herpes simplex infection
Autophagy - animal
Acrosome Reaction
0
2619-GP1
GP1
2619
GAS1
[ "growth arrest specific 1", "growth arrest-specific protein 1", "Growth arrest-specific gene-1" ]
[ "REACT:R-HSA-5635838", "REACT:R-HSA-5632684", "KEGG:hsa04340", "REACT:R-HSA-5632681", "REACT:R-HSA-5358351", "REACT:R-HSA-162582" ]
[ "Activation of SMO", "Hedgehog 'on' state", "Hedgehog signaling pathway", "Ligand-receptor interactions", "Signaling by Hedgehog", "Signal Transduction" ]
[]
[ [], [], [], [], [], [] ]
Linoleic acid (LA) metabolism
Amoebiasis
Activation of SMO
Basal cell carcinoma
2
2246-GP1
GP1
2246
FGF1
[ "fibroblast growth factor 1", "AFGF", "ECGF", "ECGF-beta", "ECGFA", "ECGFB", "FGF-alpha", "FGFA", "GLIO703", "HBGF-1", "HBGF1", "fibroblast growth factor 1", "beta-endothelial cell growth factor", "endothelial cell growth factor, alpha", "endothelial cell growth factor, beta", "fibroblast growth factor 1 (acidic)", "heparin-binding growth factor 1" ]
[ "REACT:R-HSA-1280218", "REACT:R-HSA-170984", "REACT:R-HSA-422475", "KEGG:hsa05224", "REACT:R-HSA-1280215", "REACT:R-HSA-2172127", "REACT:R-HSA-2424491", "REACT:R-HSA-1266738", "REACT:R-HSA-1643685", "REACT:R-HSA-5663202", "REACT:R-HSA-186763", "REACT:R-HSA-2871796", "REACT:R-HSA-1839124", "REACT:R-HSA-1839126", "REACT:R-HSA-2033514", "REACT:R-HSA-170968", "REACT:R-HSA-5654693", "REACT:R-HSA-5654700", "REACT:R-HSA-5654706", "REACT:R-HSA-5654712", "REACT:R-HSA-180292", "REACT:R-HSA-179812", "KEGG:hsa04390", "REACT:R-HSA-2428924", "REACT:R-HSA-168256", "REACT:R-HSA-168249", "REACT:R-HSA-74751", "REACT:R-HSA-451927", "REACT:R-HSA-912526", "REACT:R-HSA-112399", "REACT:R-HSA-5684996", "REACT:R-HSA-5683057", "KEGG:hsa04010", "KEGG:hsa05218", "REACT:R-HSA-375165", "KEGG:hsa05200", "REACT:R-HSA-198203", "KEGG:hsa04151", "REACT:R-HSA-109704", "REACT:R-HSA-1257604", "REACT:R-HSA-169893", "REACT:R-HSA-5673001", "KEGG:hsa04015", "KEGG:hsa04014", "KEGG:hsa04810", "REACT:R-HSA-8853659", "REACT:R-HSA-180336", "REACT:R-HSA-177929", "REACT:R-HSA-190236", "REACT:R-HSA-5654736", "REACT:R-HSA-5655302", "REACT:R-HSA-5654738", "REACT:R-HSA-5655253", "REACT:R-HSA-5654741", "REACT:R-HSA-5655332", "REACT:R-HSA-5654743", "REACT:R-HSA-1226099", "REACT:R-HSA-372790", "REACT:R-HSA-74752", "REACT:R-HSA-449147", "REACT:R-HSA-2586552", "REACT:R-HSA-186797", "REACT:R-HSA-1433557", "REACT:R-HSA-194138", "REACT:R-HSA-166520", "REACT:R-HSA-187687", "REACT:R-HSA-167044", "REACT:R-HSA-162582", "REACT:R-HSA-112412", "REACT:R-HSA-5218921" ]
[ "Adaptive Immune System", "ARMS-mediated activation", "Axon guidance", "Breast cancer", "Cytokine Signaling in Immune system", "DAP12 interactions", "DAP12 signaling", "Developmental Biology", "Disease", "Diseases of signal transduction", "Downstream signal transduction", "FCERI mediated MAPK activation", "FGFR1 mutant receptor activation", "FGFR2 mutant receptor activation", "FGFR3 mutant receptor activation", "Frs2-mediated activation", "FRS-mediated FGFR1 signaling", "FRS-mediated FGFR2 signaling", "FRS-mediated FGFR3 signaling", "FRS-mediated FGFR4 signaling", "GAB1 signalosome", "GRB2 events in EGFR signaling", "Hippo signaling pathway", "IGF1R signaling cascade", "Immune System", "Innate Immune System", "Insulin receptor signalling cascade", "Interleukin-2 signaling", "Interleukin receptor SHC signaling", "IRS-mediated signalling", "MAPK1/MAPK3 signaling", "MAPK family signaling cascades", "MAPK signaling pathway", "Melanoma", "NCAM signaling for neurite out-growth", "Pathways in cancer", "PI3K/AKT activation", "PI3K-Akt signaling pathway", "PI3K Cascade", "PIP3 activates AKT signaling", "Prolonged ERK activation events", "RAF/MAP kinase cascade", "Rap1 signaling pathway", "Ras signaling pathway", "Regulation of actin cytoskeleton", "RET signaling", "SHC1 events in EGFR signaling", "Signaling by EGFR", "Signaling by FGFR", "Signaling by FGFR1", "Signaling by FGFR1 in disease", "Signaling by FGFR2", "Signaling by FGFR2 in disease", "Signaling by FGFR3", "Signaling by FGFR3 in disease", "Signaling by FGFR4", "Signaling by FGFR in disease", "Signaling by GPCR", "Signaling by Insulin receptor", "Signaling by Interleukins", "Signaling by Leptin", "Signaling by PDGF", "Signaling by SCF-KIT", "Signaling by VEGF", "Signalling by NGF", "Signalling to ERKs", "Signalling to RAS", "Signal Transduction", "SOS-mediated signalling", "VEGFR2 mediated cell proliferation" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [] ]
Hemostasis
Choline catabolism
Adaptive Immune System
Amoebiasis
2
5554-GP1
GP1
5554
PRH1
[ "proline rich protein HaeIII subfamily 1", "Db-s", "PA", "PIF-S", "PRH2", "PRP-1/PRP-2", "Pr1/Pr2", "parotid acidic protein", "parotid double-band protein", "parotid isoelectric focusing variant protein", "protein C" ]
[ "KEGG:hsa04970" ]
[ "Salivary secretion" ]
[]
[ [] ]
Branched-chain amino acid catabolism
Salivary secretion
CDO in myogenesis
Neuroactive ligand-receptor interaction
1
2647-GP1
GP1
2647
BLOC1S1
[ "BLOS1", "BORCS1", "GCN5L1", "MICoA", "RT14", "BLOC-1 subunit 1", "GCN5-like protein 1", "MTA1-interacting coactivator" ]
[ "REACT:R-HSA-432722", "REACT:R-HSA-432720", "REACT:R-HSA-199991", "REACT:R-HSA-5653656" ]
[ "Golgi Associated Vesicle Biogenesis", "Lysosome Vesicle Biogenesis", "Membrane Trafficking", "Vesicle-mediated transport" ]
[]
[ [], [], [], [] ]
Bile secretion
Mineral absorption
Golgi Associated Vesicle Biogenesis
Disease
2
80267-GP1
GP1
80267
EDEM3
[ "C1orf22" ]
[ "REACT:R-HSA-901042", "REACT:R-HSA-392499", "REACT:R-HSA-597592" ]
[ "Calnexin/calreticulin cycle", "Metabolism of proteins", "Post-translational protein modification" ]
[]
[ [], [], [] ]
Calnexin/calreticulin cycle
Adherens junction
Autophagy - animal
Hemostasis
0
10401-GP1
GP1
10401
PIAS3
[ "protein inhibitor of activated STAT 3", "ZMIZ5", "protein inhibitor of activated STAT protein 3", "zinc finger, MIZ-type containing 5" ]
[ "REACT:R-HSA-73894", "KEGG:hsa04630", "REACT:R-HSA-392499", "REACT:R-HSA-5696398", "REACT:R-HSA-597592", "REACT:R-HSA-2990846", "REACT:R-HSA-4615885", "REACT:R-HSA-3232118", "KEGG:hsa04120" ]
[ "DNA Repair", "Jak-STAT signaling pathway", "Metabolism of proteins", "Nucleotide Excision Repair", "Post-translational protein modification", "SUMOylation", "SUMOylation of DNA replication proteins", "SUMOylation of transcription factors", "Ubiquitin mediated proteolysis" ]
[]
[ [], [], [], [], [], [], [], [], [] ]
NF-kappa B signaling pathway
Defective CHST6 causes MCDC1
Dectin-2 family
DNA Repair
3
9945-GP1
GP1
9945
GFPT2
[ "GFAT", "GFAT 2", "GFAT2" ]
[ "KEGG:hsa00520", "KEGG:hsa04931", "KEGG:hsa01100", "REACT:R-HSA-392499", "REACT:R-HSA-597592" ]
[ "Amino sugar and nucleotide sugar metabolism", "Insulin resistance", "Metabolic pathways", "Metabolism of proteins", "Post-translational protein modification" ]
[]
[ [], [], [], [], [] ]
G alpha (i) signalling events
Cell Cycle
Amino sugar and nucleotide sugar metabolism
Cardiac conduction
2
574455-GP1
GP1
574455
MIR193B
[ "microRNA 193b", "MIRN193B", "hsa-mir-193b" ]
[ "KEGG:hsa05206" ]
[ "MicroRNAs in cancer" ]
[]
[ [] ]
Acute myeloid leukemia
Integration of energy metabolism
Base excision repair
MicroRNAs in cancer
3
26146-GP1
GP1
26146
TRAF3IP1
[ "TRAF3 interacting protein 1", "FAP116", "IFT54", "MIP-T3", "MIPT3", "SLSN9", "TRAF3-interacting protein 1", "TNF receptor-associated factor 3 interacting protein 1" ]
[ "REACT:R-HSA-5617833", "REACT:R-HSA-5620924", "REACT:R-HSA-1852241" ]
[ "Cilium Assembly", "Intraflagellar transport", "Organelle biogenesis and maintenance" ]
[]
[ [], [], [] ]
Cilium Assembly
Cytosolic sensors of pathogen-associated DNA
Herpes simplex infection
Choline metabolism in cancer
0
3939-GP1
GP1
3939
LDHA
[ "lactate dehydrogenase A", "GSD11", "HEL-S-133P", "LDHM", "PIG19", "LDH muscle subunit", "LDH-M", "cell proliferation-inducing gene 19 protein", "lactate dehydrogenase M", "proliferation-inducing gene 19" ]
[ "KEGG:hsa05230", "KEGG:hsa00270", "KEGG:hsa04922", "KEGG:hsa00010", "KEGG:hsa04066", "KEGG:hsa01100", "REACT:R-HSA-1430728", "KEGG:hsa00640", "KEGG:hsa00620", "REACT:R-HSA-70268" ]
[ "Central carbon metabolism in cancer", "Cysteine and methionine metabolism", "Glucagon signaling pathway", "Glycolysis / Gluconeogenesis", "HIF-1 signaling pathway", "Metabolic pathways", "Metabolism", "Propanoate metabolism", "Pyruvate metabolism", "Pyruvate metabolism" ]
[]
[ [], [], [], [], [], [], [], [], [], [] ]
Tight junction
Mitophagy - animal
Alcoholism
Central carbon metabolism in cancer
3
7515-GP1
GP1
7515
XRCC1
[ "X-ray repair cross complementing 1", "SCAR26", "DNA repair protein XRCC1", "X-ray repair cross-complementing protein 1" ]
[ "KEGG:hsa03410", "REACT:R-HSA-73884", "KEGG:hsa_M00296", "REACT:R-HSA-5693532", "REACT:R-HSA-5693538", "REACT:R-HSA-5696398", "REACT:R-HSA-73933" ]
[ "Base excision repair", "Base Excision Repair", "BER complex", "DNA Double-Strand Break Repair", "Homology Directed Repair", "Nucleotide Excision Repair", "Resolution of Abasic Sites (AP sites)" ]
[]
[ [], [], [], [], [], [], [] ]
Spliceosome
G alpha (s) signalling events
PI3K-Akt signaling pathway
Base excision repair
3
2946-GP1
GP1
2946
GSTM2
[ "GST4", "GSTM2-2", "GTHMUS", "glutathione S-transferase Mu 2", "GST class-mu 2", "GST, muscle", "epididymis secretory sperm binding protein", "glutathione S-transferase 4", "glutathione S-transferase M1" ]
[ "REACT:R-HSA-211859", "KEGG:hsa05204", "KEGG:hsa00982", "REACT:R-HSA-156590", "KEGG:hsa00480", "REACT:R-HSA-1430728", "REACT:R-HSA-156580", "KEGG:hsa01524" ]
[ "Biological oxidations", "Chemical carcinogenesis", "Drug metabolism - cytochrome P450", "Glutathione conjugation", "Glutathione metabolism", "Metabolism", "Phase II conjugation", "Platinum drug resistance" ]
[]
[ [], [], [], [], [], [], [], [] ]
Dectin-2 family
Adherens junction
Activated TLR4 signalling
Biological oxidations
3
2801-GP1
GP1
2801
GOLGA2
[ "golgin A2", "GM130", "golgin subfamily A member 2", "GM130 autoantigen", "Golgi matrix protein GM130", "SY11 protein", "golgin-95" ]
[ "REACT:R-HSA-1640170", "REACT:R-HSA-69278", "REACT:R-HSA-6807878", "REACT:R-HSA-1643685", "REACT:R-HSA-199977", "REACT:R-HSA-199991", "REACT:R-HSA-392499", "REACT:R-HSA-68875", "REACT:R-HSA-68886", "REACT:R-HSA-8863678", "REACT:R-HSA-597592", "REACT:R-HSA-948021", "REACT:R-HSA-5653656" ]
[ "Cell Cycle", "Cell Cycle, Mitotic", "COPI-mediated anterograde transport", "Disease", "ER to Golgi Anterograde Transport", "Membrane Trafficking", "Metabolism of proteins", "Mitotic Prophase", "M Phase", "Neurodegenerative Diseases", "Post-translational protein modification", "Transport to the Golgi and subsequent modification", "Vesicle-mediated transport" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [] ]
Cell Cycle
Gap junction
Apoptosis
Complex I biogenesis
0
2160-GP1
GP1
2160
F11
[ "coagulation factor XI", "FXI", "PTA", "coagulation factor XI", "coagualtion factor XI" ]
[ "KEGG:hsa04610", "REACT:R-HSA-109582" ]
[ "Complement and coagulation cascades", "Hemostasis" ]
[]
[ [], [] ]
Complement and coagulation cascades
Metabolism
Mitophagy - animal
Gap junction
0
367-GP1
GP1
367
AR
[ "androgen receptor", "AIS", "AR8", "DHTR", "HUMARA", "HYSP1", "KD", "NR3C4", "SBMA", "SMAX1", "TFM", "androgen receptor", "dihydrotestosterone receptor", "nuclear receptor subfamily 3 group C member 4" ]
[ "REACT:R-HSA-5688426", "REACT:R-HSA-74160", "REACT:R-HSA-212436", "REACT:R-HSA-392499", "REACT:R-HSA-383280", "KEGG:hsa04114", "KEGG:hsa05200", "REACT:R-HSA-597592", "KEGG:hsa05215", "REACT:R-HSA-195258", "REACT:R-HSA-194315", "REACT:R-HSA-162582", "REACT:R-HSA-5689880" ]
[ "Deubiquitination", "Gene Expression", "Generic Transcription Pathway", "Metabolism of proteins", "Nuclear Receptor transcription pathway", "Oocyte meiosis", "Pathways in cancer", "Post-translational protein modification", "Prostate cancer", "RHO GTPase Effectors", "Signaling by Rho GTPases", "Signal Transduction", "Ub-specific processing proteases" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [] ]
Deubiquitination
Ca2+ activated K+ channels
eNOS activation and regulation
Chemokine receptors bind chemokines
0
343173-GP1
GP1
343173
OR2T3
[ "olfactory receptor 2T3", "seven transmembrane helix receptor" ]
[ "REACT:R-HSA-388396", "REACT:R-HSA-381753", "KEGG:hsa04740", "REACT:R-HSA-372790", "REACT:R-HSA-162582" ]
[ "GPCR downstream signaling", "Olfactory Signaling Pathway", "Olfactory transduction", "Signaling by GPCR", "Signal Transduction" ]
[]
[ [], [], [], [], [] ]
Scavenging of heme from plasma
Neuronal System
Metabolism
GPCR downstream signaling
3
9412-GP1
GP1
9412
MED21
[ "mediator complex subunit 21", "SRB7", "SURB7", "hSrb7", "mediator of RNA polymerase II transcription subunit 21", "RNAPII complex component SRB7" ]
[ "REACT:R-HSA-1266738", "REACT:R-HSA-1430728", "REACT:R-HSA-1989781" ]
[ "Developmental Biology", "Metabolism", "PPARA activates gene expression" ]
[]
[ [], [], [] ]
Developmental Biology
Heme biosynthesis
eNOS activation and regulation
Mineral absorption
0
10171-GP1
GP1
10171
RCL1
[ "RNA terminal phosphate cyclase like 1", "RNAC", "RPCL1", "RNA cyclase homolog" ]
[ "REACT:R-HSA-74160", "REACT:R-HSA-72312" ]
[ "Gene Expression", "rRNA processing" ]
[]
[ [], [] ]
Breast cancer
Acrosome Reaction
Amoebiasis
Gene Expression
3
7110-GP1
GP1
7110
TMF1
[ "TATA element modulatory factor 1", "ARA160", "TATA element modulatory factor" ]
[ "REACT:R-HSA-199991", "REACT:R-HSA-5653656" ]
[ "Membrane Trafficking", "Vesicle-mediated transport" ]
[]
[ [], [] ]
Alzheimer's disease
G alpha (s) signalling events
Membrane Trafficking
Mitophagy - animal
2
100528030-GP1
GP1
100528030
POC1B-GALNT4
[ "GalNAc-T4", "POC1B-GALNT4 protein", "POC1B-GALNT4 fusion", "pp-GaNTase 4" ]
[ "KEGG:hsa01100" ]
[ "Metabolic pathways" ]
[]
[ [] ]
Tight junction
NOD-like receptor signaling pathway
Metabolic pathways
Cholinergic synapse
2
84617-GP1
GP1
84617
TUBB6
[ "tubulin beta 6 class V", "FPVEPD", "HsT1601", "TUBB-5", "tubulin beta-6 chain", "class V beta-tubulin", "tubulin beta MGC4083", "tubulin beta class V", "tubulin, beta 6" ]
[ "REACT:R-HSA-390466", "KEGG:hsa04540", "REACT:R-HSA-392499", "KEGG:hsa05130", "KEGG:hsa04145", "REACT:R-HSA-389977", "REACT:R-HSA-391251" ]
[ "Chaperonin-mediated protein folding", "Gap junction", "Metabolism of proteins", "Pathogenic Escherichia coli infection", "Phagosome", "Post-chaperonin tubulin folding pathway", "Protein folding" ]
[]
[ [], [], [], [], [], [], [] ]
Bladder cancer
Chaperonin-mediated protein folding
Mineral absorption
Scavenging of heme from plasma
1
78988-GP1
GP1
78988
MRPL57
[ "mitochondrial ribosomal protein L57", "MRP63", "bMRP63", "ribosomal protein 63, mitochondrial", "hMRP63", "mitochondrial ribosomal protein 63", "mitochondrial ribosomal protein bMRP63" ]
[ "REACT:R-HSA-5368287", "REACT:R-HSA-5389840", "REACT:R-HSA-5368286", "REACT:R-HSA-5419276", "REACT:R-HSA-1852241" ]
[ "Mitochondrial translation", "Mitochondrial translation elongation", "Mitochondrial translation initiation", "Mitochondrial translation termination", "Organelle biogenesis and maintenance" ]
[]
[ [], [], [], [], [] ]
Mitochondrial translation
eNOS activation and regulation
Cytosolic DNA-sensing pathway
TGF-beta signaling pathway
0
3155-GP1
GP1
3155
HMGCL
[ "HL", "HMG-CoA lyase" ]
[ "KEGG:hsa00650", "REACT:R-HSA-74182", "KEGG:hsa01100", "REACT:R-HSA-1430728", "KEGG:hsa04146", "KEGG:hsa00072", "REACT:R-HSA-77111" ]
[ "Butanoate metabolism", "Ketone body metabolism", "Metabolic pathways", "Metabolism", "Peroxisome", "Synthesis and degradation of ketone bodies", "Synthesis of Ketone Bodies" ]
[]
[ [], [], [], [], [], [], [] ]
Dorso-ventral axis formation
Butanoate metabolism
TGF-beta signaling pathway
Epstein-Barr virus infection
1
29801-GP1
GP1
29801
ZDHHC8
[ "ZDHHCL1", "ZNF378", "membrane-associated DHHC8 zinc finger protein", "zinc finger DHHC-type containing 8", "zinc finger protein 378", "zinc finger, DHHC domain like containing 1" ]
[ "REACT:R-HSA-194223", "REACT:R-HSA-174824", "REACT:R-HSA-1430728" ]
[ "HDL-mediated lipid transport", "Lipoprotein metabolism", "Metabolism" ]
[]
[ [], [], [] ]
Neuronal System
Developmental Biology
G alpha (s) signalling events
HDL-mediated lipid transport
3
55183-GP1
GP1
55183
RIF1
[ "replication timing regulatory factor 1", "telomere-associated protein RIF1", "RAP1 interacting factor homolog", "rap1-interacting factor 1 homolog" ]
[ "REACT:R-HSA-5693532", "REACT:R-HSA-73894" ]
[ "DNA Double-Strand Break Repair", "DNA Repair" ]
[]
[ [], [] ]
DNA Double-Strand Break Repair
Metabolism
Phototransduction
Breast cancer
0
57192-GP1
GP1
57192
MCOLN1
[ "mucolipin TRP cation channel 1", "MG-2", "ML1", "ML4", "MLIV", "MST080", "MSTP080", "TRP-ML1", "TRPM-L1", "TRPML1", "mucolipin-1", "mucolipidin", "mucolipidosis type IV protein", "mucolipin 1", "transient receptor potential channel mucolipin 1", "transient receptor potential mucolipin 1" ]
[ "REACT:R-HSA-983712", "REACT:R-HSA-917937", "KEGG:hsa04142", "REACT:R-HSA-2672351", "REACT:R-HSA-917977", "REACT:R-HSA-382551", "REACT:R-HSA-3295583" ]
[ "Ion channel transport", "Iron uptake and transport", "Lysosome", "Stimuli-sensing channels", "Transferrin endocytosis and recycling", "Transmembrane transport of small molecules", "TRP channels" ]
[]
[ [], [], [], [], [], [], [] ]
G alpha (q) signalling events
Breast cancer
Ion channel transport
Fertilization
2
283209-GP1
GP1
283209
PGM2L1
[ "BM32A", "PMMLP" ]
[ "KEGG:hsa00500" ]
[ "Starch and sucrose metabolism" ]
[]
[ [] ]
Tight junction
Starch and sucrose metabolism
G alpha (i) signalling events
DAP12 interactions
1
81697-GP1
GP1
81697
OR2B2
[ "OR2B2Q", "OR2B9", "OR6-1", "dJ193B12.4", "hs6M1-10", "olfactory receptor 2B2", "olfactory receptor 2B9", "olfactory receptor 6-1", "olfactory receptor OR6-2" ]
[ "REACT:R-HSA-388396", "REACT:R-HSA-381753", "KEGG:hsa04740", "REACT:R-HSA-372790", "REACT:R-HSA-162582" ]
[ "GPCR downstream signaling", "Olfactory Signaling Pathway", "Olfactory transduction", "Signaling by GPCR", "Signal Transduction" ]
[]
[ [], [], [], [], [] ]
Dilated cardiomyopathy
Linoleic acid (LA) metabolism
GPCR downstream signaling
Developmental Biology
2
120796-GP1
GP1
120796
OR56A1
[ "OR11-75", "olfactory receptor 56A1", "olfactory receptor OR11-75" ]
[ "REACT:R-HSA-388396", "REACT:R-HSA-381753", "KEGG:hsa04740", "REACT:R-HSA-372790", "REACT:R-HSA-162582" ]
[ "GPCR downstream signaling", "Olfactory Signaling Pathway", "Olfactory transduction", "Signaling by GPCR", "Signal Transduction" ]
[]
[ [], [], [], [], [] ]
Phototransduction
GPCR downstream signaling
Endocytosis
Cell cycle
1
4207-GP1
GP1
4207
BORCS8-MEF2B
[ "RSRFR2", "myocyte-specific enhancer factor 2B", "myocyte enhancer factor 2B", "serum response factor-like protein 2" ]
[ "KEGG:hsa04371", "KEGG:hsa04022" ]
[ "Apelin signaling pathway", "cGMP-PKG signaling pathway" ]
[]
[ [], [] ]
Mitophagy - animal
Apelin signaling pathway
Muscle contraction
Epstein-Barr virus infection
1
84557-GP1
GP1
84557
MAP1LC3A
[ "microtubule associated protein 1 light chain 3 alpha", "ATG8E", "MAP1ALC3", "MAP1BLC3", "MAP1 light chain 3-like protein 1" ]
[ "REACT:R-HSA-2262752", "KEGG:hsa04216", "REACT:R-HSA-1632852", "REACT:R-HSA-5205647", "REACT:R-HSA-5205685" ]
[ "Cellular responses to stress", "Ferroptosis", "Macroautophagy", "Mitophagy", "Pink/Parkin Mediated Mitophagy" ]
[]
[ [], [], [], [], [] ]
Cell Cycle
Oocyte meiosis
Spliceosome
Cellular responses to stress
3
25769-GP1
GP1
25769
SLC24A2
[ "solute carrier family 24 member 2", "NCKX2", "sodium/potassium/calcium exchanger 2" ]
[ "REACT:R-HSA-425407", "REACT:R-HSA-425561", "REACT:R-HSA-382551" ]
[ "SLC-mediated transmembrane transport", "Sodium/Calcium exchangers", "Transmembrane transport of small molecules" ]
[]
[ [], [], [] ]
Alcoholism
Mitophagy - animal
Autophagy - animal
SLC-mediated transmembrane transport
3
406886-GP1
GP1
406886
MIRLET7D
[ "microRNA let-7d", "MIRNLET7D", "hsa-let-7d" ]
[ "KEGG:hsa05206" ]
[ "MicroRNAs in cancer" ]
[]
[ [] ]
Cell Cycle
Cell-Cell communication
MicroRNAs in cancer
Cul3-SPOP complex
2
23431-GP1
GP1
23431
AP4E1
[ "CPSQ4", "SPG51", "STUT1", "AP-4 complex subunit epsilon-1", "AP-4 adaptor complex subunit epsilon", "epsilon-adaptin" ]
[ "REACT:R-HSA-432722", "KEGG:hsa04142", "REACT:R-HSA-432720", "REACT:R-HSA-199991", "REACT:R-HSA-5653656" ]
[ "Golgi Associated Vesicle Biogenesis", "Lysosome", "Lysosome Vesicle Biogenesis", "Membrane Trafficking", "Vesicle-mediated transport" ]
[]
[ [], [], [], [], [] ]
Herpes simplex infection
Cell cycle
Epstein-Barr virus infection
Golgi Associated Vesicle Biogenesis
3
10284-GP1
GP1
10284
SAP18
[ "Sin3A associated protein 18", "2HOR0202", "SAP18P", "cell growth inhibiting protein 38", "cell growth-inhibiting gene 38 protein", "epididymis secretory sperm binding protein" ]
[ "REACT:R-HSA-3247509", "REACT:R-HSA-4839726", "REACT:R-HSA-212165", "KEGG:hsa_M00430", "REACT:R-HSA-74160", "REACT:R-HSA-3214815", "KEGG:hsa03015", "REACT:R-HSA-427413", "KEGG:hsa03013" ]
[ "Chromatin modifying enzymes", "Chromatin organization", "Epigenetic regulation of gene expression", "Exon junction complex (EJC)", "Gene Expression", "HDACs deacetylate histones", "mRNA surveillance pathway", "NoRC negatively regulates rRNA expression", "RNA transport" ]
[]
[ [], [], [], [], [], [], [], [], [] ]
Chromatin modifying enzymes
Gap junction
G alpha (12/13) signalling events
G alpha (i) signalling events
0
8740-GP1
GP1
8740
TNFSF14
[ "TNF superfamily member 14", "CD258", "HVEML", "LIGHT", "LTg", "herpesvirus entry mediator ligand", "tumor necrosis factor ligand 1D", "tumor necrosis factor superfamily member 14" ]
[ "KEGG:hsa04060", "REACT:R-HSA-1280215", "KEGG:hsa05168", "REACT:R-HSA-168256", "KEGG:hsa04064", "REACT:R-HSA-5669034" ]
[ "Cytokine-cytokine receptor interaction", "Cytokine Signaling in Immune system", "Herpes simplex infection", "Immune System", "NF-kappa B signaling pathway", "TNFs bind their physiological receptors" ]
[]
[ [], [], [], [], [], [] ]
African trypanosomiasis
Spliceosome
Disease
Cytokine-cytokine receptor interaction
3
7428-GP1
GP1
7428
VHL
[ "von Hippel-Lindau tumor suppressor", "HRCA1", "RCA1", "VHL1", "pVHL", "von Hippel-Lindau disease tumor suppressor", "elongin binding protein", "protein G7" ]
[ "REACT:R-HSA-1280218", "REACT:R-HSA-2262752", "REACT:R-HSA-2262749", "REACT:R-HSA-983169", "KEGG:hsa_M00383", "KEGG:hsa04066", "REACT:R-HSA-168256", "KEGG:hsa05200", "KEGG:hsa05211", "KEGG:hsa04120" ]
[ "Adaptive Immune System", "Cellular responses to stress", "Cellular response to hypoxia", "Class I MHC mediated antigen processing & presentation", "ECV complex", "HIF-1 signaling pathway", "Immune System", "Pathways in cancer", "Renal cell carcinoma", "Ubiquitin mediated proteolysis" ]
[]
[ [], [], [], [], [], [], [], [], [], [] ]
ABC transporters
Alzheimer's disease
Adaptive Immune System
Acrosome Reaction
2
3446-GP1
GP1
3446
IFNA10
[ "interferon alpha 10", "IFN-alphaC", "interferon alpha-10", "IFN-alpha-10", "interferon alpha-6L", "interferon alpha-C", "leIF C" ]
[ "KEGG:hsa05320", "KEGG:hsa04060", "REACT:R-HSA-1280215", "KEGG:hsa04623", "REACT:R-HSA-109582", "KEGG:hsa05161", "KEGG:hsa05160", "KEGG:hsa05168", "REACT:R-HSA-168256", "KEGG:hsa05164", "REACT:R-HSA-168249", "REACT:R-HSA-909733", "REACT:R-HSA-913531", "KEGG:hsa04630", "KEGG:hsa05162", "KEGG:hsa04650", "KEGG:hsa04621", "KEGG:hsa04151", "REACT:R-HSA-912694", "KEGG:hsa04622", "KEGG:hsa04620", "REACT:R-HSA-933541", "KEGG:hsa05152" ]
[ "Autoimmune thyroid disease", "Cytokine-cytokine receptor interaction", "Cytokine Signaling in Immune system", "Cytosolic DNA-sensing pathway", "Hemostasis", "Hepatitis B", "Hepatitis C", "Herpes simplex infection", "Immune System", "Influenza A", "Innate Immune System", "Interferon alpha/beta signaling", "Interferon Signaling", "Jak-STAT signaling pathway", "Measles", "Natural killer cell mediated cytotoxicity", "NOD-like receptor signaling pathway", "PI3K-Akt signaling pathway", "Regulation of IFNA signaling", "RIG-I-like receptor signaling pathway", "Toll-like receptor signaling pathway", "TRAF6 mediated IRF7 activation", "Tuberculosis" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [] ]
FGFR2 alternative splicing
Autoimmune thyroid disease
Neuronal System
Arginine biosynthesis
1
55957-GP1
GP1
55957
LIN37
[ "F25965", "ZK418.4", "protein lin-37 homolog", "antolefinin", "lin-37 homolog", "protein F25965" ]
[ "REACT:R-HSA-1640170", "REACT:R-HSA-69278", "REACT:R-HSA-1538133", "REACT:R-HSA-69275", "REACT:R-HSA-156711" ]
[ "Cell Cycle", "Cell Cycle, Mitotic", "G0 and Early G1", "G2/M Transition", "Polo-like kinase mediated events" ]
[]
[ [], [], [], [], [] ]
Cell Cycle
Chylomicron-mediated lipid transport
MicroRNAs in cancer
Collagen chain trimerization
0
5437-GP1
GP1
5437
POLR2H
[ "RNA polymerase II, I and III subunit H", "RPABC3", "RPB17", "RPB8", "DNA-directed RNA polymerase II subunit H", "RNA polymerase II subunit H", "RPB8 homolog", "polymerase (RNA) II subunit H" ]
[ "REACT:R-HSA-5619507", "KEGG:hsa04623", "REACT:R-HSA-1834949", "REACT:R-HSA-1266738", "REACT:R-HSA-1643685", "REACT:R-HSA-5663202", "REACT:R-HSA-73894", "REACT:R-HSA-6782135", "REACT:R-HSA-212165", "KEGG:hsa05169", "REACT:R-HSA-6803529", "REACT:R-HSA-1839126", "REACT:R-HSA-112382", "REACT:R-HSA-113418", "REACT:R-HSA-74160", "REACT:R-HSA-212436", "REACT:R-HSA-211000", "REACT:R-HSA-167287", "REACT:R-HSA-162906", "REACT:R-HSA-162587", "REACT:R-HSA-167169", "REACT:R-HSA-167161", "KEGG:hsa05016", "REACT:R-HSA-168256", "REACT:R-HSA-5663205", "REACT:R-HSA-168254", "REACT:R-HSA-168255", "REACT:R-HSA-168249", "REACT:R-HSA-162599", "KEGG:hsa01100", "REACT:R-HSA-203927", "REACT:R-HSA-72086", "REACT:R-HSA-72172", "REACT:R-HSA-72163", "REACT:R-HSA-72165", "REACT:R-HSA-427413", "REACT:R-HSA-5696398", "REACT:R-HSA-167290", "KEGG:hsa00230", "KEGG:hsa00240", "REACT:R-HSA-73777", "KEGG:hsa_M00182", "KEGG:hsa_M00180", "REACT:R-HSA-167162", "REACT:R-HSA-73780", "KEGG:hsa_M00181", "REACT:R-HSA-74158", "REACT:R-HSA-76046", "REACT:R-HSA-73980", "REACT:R-HSA-674695", "REACT:R-HSA-73776", "REACT:R-HSA-73857", "REACT:R-HSA-75955", "REACT:R-HSA-75953", "REACT:R-HSA-73854", "REACT:R-HSA-73772", "REACT:R-HSA-73864", "REACT:R-HSA-73762", "REACT:R-HSA-73863", "REACT:R-HSA-190236", "REACT:R-HSA-5654738", "REACT:R-HSA-5655253", "REACT:R-HSA-1226099", "REACT:R-HSA-162582", "REACT:R-HSA-5578749", "REACT:R-HSA-3700989", "REACT:R-HSA-167172", "REACT:R-HSA-168325" ]
[ "Activation of HOX genes during differentiation", "Cytosolic DNA-sensing pathway", "Cytosolic sensors of pathogen-associated DNA", "Developmental Biology", "Disease", "Diseases of signal transduction", "DNA Repair", "Dual incision in TC-NER", "Epigenetic regulation of gene expression", "Epstein-Barr virus infection", "FGFR2 alternative splicing", "FGFR2 mutant receptor activation", "Formation of RNA Pol II elongation complex", "Formation of the Early Elongation Complex", "Gene Expression", "Generic Transcription Pathway", "Gene Silencing by RNA", "HIV elongation arrest and recovery", "HIV Infection", "HIV Life Cycle", "HIV Transcription Elongation", "HIV Transcription Initiation", "Huntington's disease", "Immune System", "Infectious disease", "Influenza Infection", "Influenza Life Cycle", "Innate Immune System", "Late Phase of HIV Life Cycle", "Metabolic pathways", "MicroRNA (miRNA) biogenesis", "mRNA Capping", "mRNA Splicing", "mRNA Splicing - Major Pathway", "mRNA Splicing - Minor Pathway", "NoRC negatively regulates rRNA expression", "Nucleotide Excision Repair", "Pausing and recovery of HIV elongation", "Purine metabolism", "Pyrimidine metabolism", "RNA Polymerase I Chain Elongation", "RNA polymerase I, eukaryotes", "RNA polymerase II, eukaryotes", "RNA Polymerase II HIV Promoter Escape", "RNA Polymerase III Chain Elongation", "RNA polymerase III, eukaryotes", "RNA Polymerase III Transcription", "RNA Polymerase III Transcription Initiation", "RNA Polymerase III Transcription Termination", "RNA Polymerase II Pre-transcription Events", "RNA Polymerase II Promoter Escape", "RNA Polymerase II Transcription", "RNA Polymerase II Transcription Elongation", "RNA Polymerase II Transcription Initiation", "RNA Polymerase I Promoter Clearance", "RNA Polymerase I Promoter Escape", "RNA Polymerase I Transcription", "RNA Polymerase I Transcription Initiation", "RNA Polymerase I Transcription Termination", "Signaling by FGFR", "Signaling by FGFR2", "Signaling by FGFR2 in disease", "Signaling by FGFR in disease", "Signal Transduction", "Transcriptional regulation by small RNAs", "Transcriptional Regulation by TP53", "Transcription of the HIV genome", "Viral Messenger RNA Synthesis" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [] ]
Disease
Antimicrobial peptides
Cilium Assembly
Activation of HOX genes during differentiation
3
81605-GP1
GP1
81605
URM1
[ "ubiquitin related modifier 1", "C9orf74", "ubiquitin-related modifier 1" ]
[ "REACT:R-HSA-74160", "KEGG:hsa04122", "REACT:R-HSA-72306" ]
[ "Gene Expression", "Sulfur relay system", "tRNA processing" ]
[]
[ [], [], [] ]
Amphetamine addiction
Gene Expression
Metabolism
Metal ion SLC transporters
1
4994-GP1
GP1
4994
OR3A1
[ "OLFRA03", "OR17-40", "OR17-82", "OR40", "olfactory receptor 3A1", "olfactory receptor 17-40", "olfactory receptor OR17-15" ]
[ "REACT:R-HSA-388396", "REACT:R-HSA-381753", "KEGG:hsa04740", "REACT:R-HSA-372790", "REACT:R-HSA-162582" ]
[ "GPCR downstream signaling", "Olfactory Signaling Pathway", "Olfactory transduction", "Signaling by GPCR", "Signal Transduction" ]
[]
[ [], [], [], [], [] ]
Hemostasis
Tight junction
GPCR downstream signaling
Bile secretion
2
57504-GP1
GP1
57504
MTA3
[ "metastasis associated 1 family member 3", "metastasis-associated protein MTA3", "metastasis associated gene family, member 3" ]
[ "REACT:R-HSA-3247509", "REACT:R-HSA-4839726", "REACT:R-HSA-212165", "REACT:R-HSA-74160", "REACT:R-HSA-3214815", "REACT:R-HSA-73854", "REACT:R-HSA-73864", "REACT:R-HSA-73762" ]
[ "Chromatin modifying enzymes", "Chromatin organization", "Epigenetic regulation of gene expression", "Gene Expression", "HDACs deacetylate histones", "RNA Polymerase I Promoter Clearance", "RNA Polymerase I Transcription", "RNA Polymerase I Transcription Initiation" ]
[]
[ [], [], [], [], [], [], [], [] ]
Influenza A
Dorso-ventral axis formation
G alpha (12/13) signalling events
Chromatin modifying enzymes
3
283869-GP1
GP1
283869
NPW
[ "neuropeptide W", "L8", "L8C", "PPL8", "PPNPW", "neuropeptide W", "hPPL8", "prepro-neuropeptide W", "preproprotein L8" ]
[ "REACT:R-HSA-418594", "REACT:R-HSA-388396", "REACT:R-HSA-500792", "REACT:R-HSA-375276", "REACT:R-HSA-372790", "REACT:R-HSA-162582" ]
[ "G alpha (i) signalling events", "GPCR downstream signaling", "GPCR ligand binding", "Peptide ligand-binding receptors", "Signaling by GPCR", "Signal Transduction" ]
[]
[ [], [], [], [], [], [] ]
Activation of AMPA receptors
Neuronal System
African trypanosomiasis
G alpha (i) signalling events
3
171023-GP1
GP1
171023
ASXL1
[ "ASXL transcriptional regulator 1", "BOPS", "MDS", "polycomb group protein ASXL1", "additional sex combs like 1, transcriptional regulator", "additional sex combs like transcriptional regulator 1" ]
[ "REACT:R-HSA-5688426", "REACT:R-HSA-392499", "REACT:R-HSA-597592", "REACT:R-HSA-5689603" ]
[ "Deubiquitination", "Metabolism of proteins", "Post-translational protein modification", "UCH proteinases" ]
[]
[ [], [], [], [] ]
Arginine and proline metabolism
Muscle contraction
Deubiquitination
Cell Cycle
2
9948-GP1
GP1
9948
WDR1
[ "WD repeat domain 1", "AIP1", "HEL-S-52", "NORI-1", "PFITS", "WD repeat-containing protein 1", "actin-interacting protein 1", "epididymis secretory protein Li 52" ]
[ "REACT:R-HSA-109582", "REACT:R-HSA-76002", "REACT:R-HSA-114608" ]
[ "Hemostasis", "Platelet activation, signaling and aggregation", "Platelet degranulation" ]
[]
[ [], [], [] ]
RNA transport
Hemostasis
Biosynthesis of amino acids
Butanoate metabolism
1
8424-GP1
GP1
8424
BBOX1
[ "BBH", "G-BBH", "gamma-BBH" ]
[ "REACT:R-HSA-70895", "REACT:R-HSA-71262", "KEGG:hsa00310", "REACT:R-HSA-1430728", "REACT:R-HSA-71291" ]
[ "Branched-chain amino acid catabolism", "Carnitine synthesis", "Lysine degradation", "Metabolism", "Metabolism of amino acids and derivatives" ]
[]
[ [], [], [], [], [] ]
Branched-chain amino acid catabolism
Circadian rhythm
ABC transporters
African trypanosomiasis
0
100287932-GP1
GP1
100287932
TIMM23
[ "translocase of inner mitochondrial membrane 23", "TIM23", "mitochondrial import inner membrane translocase subunit Tim23", "translocase of the inner mitochondrial membrane" ]
[ "REACT:R-HSA-392499", "REACT:R-HSA-1268020" ]
[ "Metabolism of proteins", "Mitochondrial protein import" ]
[]
[ [], [] ]
Metabolism of proteins
Non-small cell lung cancer
TGF-beta signaling pathway
Alpha-defensins
0
51637-GP1
GP1
51637
RTRAF
[ "RNA transcription, translation and transport factor", "C14orf166", "CGI-99", "CGI99", "CLE", "CLE7", "LCRP369", "RLLM1", "hCLE", "hCLE1", "RNA transcription, translation and transport factor protein", "CLE7 homolog", "RLL motif containing 1" ]
[ "REACT:R-HSA-74160", "REACT:R-HSA-72306", "REACT:R-HSA-6784531" ]
[ "Gene Expression", "tRNA processing", "tRNA processing in the nucleus" ]
[]
[ [], [], [] ]
Neuroactive ligand-receptor interaction
Hippo signaling
Gene Expression
Tight junction
2
204-GP1
GP1
204
AK2
[ "adenylate kinase 2", "ADK2", "adenylate kinase 2, mitochondrial", "adenylate monophosphate kinase" ]
[ "KEGG:hsa01100", "REACT:R-HSA-1430728", "REACT:R-HSA-15869", "KEGG:hsa00230", "KEGG:hsa00730" ]
[ "Metabolic pathways", "Metabolism", "Metabolism of nucleotides", "Purine metabolism", "Thiamine metabolism" ]
[]
[ [], [], [], [], [] ]
Gap junction
Metabolic pathways
Tight junction
FGFR2 alternative splicing
1
8332-GP1
GP1
8332
H2AC16
[ "H2A clustered histone 16", "H2A.i", "H2A/i", "H2AC11", "H2AC13", "H2AC15", "H2AC17", "H2AFI", "HIST1H2AL", "dJ193B12.9", "histone H2A type 1", "H2A histone family, member I", "H2A.1", "histone 1, H2al", "histone H2A/ptl", "histone cluster 1 H2A family member l", "histone cluster 1, H2al" ]
[ "KEGG:hsa05034", "REACT:R-HSA-3247509", "REACT:R-HSA-4839726", "REACT:R-HSA-5688426", "REACT:R-HSA-3214847", "REACT:R-HSA-3214815", "REACT:R-HSA-392499", "REACT:R-HSA-5689901", "REACT:R-HSA-597592", "KEGG:hsa05322", "REACT:R-HSA-5689880", "REACT:R-HSA-5689603" ]
[ "Alcoholism", "Chromatin modifying enzymes", "Chromatin organization", "Deubiquitination", "HATs acetylate histones", "HDACs deacetylate histones", "Metabolism of proteins", "Metalloprotease DUBs", "Post-translational protein modification", "Systemic lupus erythematosus", "Ub-specific processing proteases", "UCH proteinases" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [] ]
Rap1 signaling pathway
Alcoholism
Epigenetic regulation of gene expression
cAMP signaling pathway
1
2213-GP1
GP1
2213
FCGR2B
[ "Fc fragment of IgG receptor IIb", "CD32", "CD32B", "FCG2", "FCGR2C", "FcRII-c", "IGFR2", "CDw32", "Fc gamma RIIb", "Fc gamma receptor IIb", "Fc-gamma RII-c", "Fc-gamma-RIIc", "IgG Fc receptor II-c", "fc-gamma RII-b", "fc-gamma-RIIb", "fcRII-b", "igG Fc receptor II-b" ]
[ "REACT:R-HSA-1280218", "KEGG:hsa04662", "REACT:R-HSA-168256", "KEGG:hsa05162", "KEGG:hsa04380", "KEGG:hsa04145", "KEGG:hsa05150", "KEGG:hsa05152" ]
[ "Adaptive Immune System", "B cell receptor signaling pathway", "Immune System", "Measles", "Osteoclast differentiation", "Phagosome", "Staphylococcus aureus infection", "Tuberculosis" ]
[]
[ [], [], [], [], [], [], [], [] ]
Cargo trafficking to the periciliary membrane
Dorso-ventral axis formation
Adaptive Immune System
Choline catabolism
2
7172-GP1
GP1
7172
TPMT
[ "TPMTD" ]
[ "REACT:R-HSA-211859", "KEGG:hsa00983", "REACT:R-HSA-1430728", "REACT:R-HSA-156581", "REACT:R-HSA-156580" ]
[ "Biological oxidations", "Drug metabolism - other enzymes", "Metabolism", "Methylation", "Phase II conjugation" ]
[]
[ [], [], [], [], [] ]
Biological oxidations
Chemokine receptors bind chemokines
G alpha (12/13) signalling events
HRD1/SEL1 ERAD complex
0
51019-GP1
GP1
51019
WASHC3
[ "WASH complex subunit 3", "CCDC53", "CGI-116", "WASH complex subunit 3", "WASH complex subunit CCDC53", "coiled-coil domain containing 53", "coiled-coil domain-containing protein 53" ]
[ "KEGG:hsa04144" ]
[ "Endocytosis" ]
[]
[ [] ]
Ether lipid metabolism
Cilium Assembly
FGFR2 alternative splicing
Endocytosis
3
158983-GP1
GP1
158983
H2BW1
[ "H2B.W histone 1", "H2BFWT", "histone H2B type W-T" ]
[ "KEGG:hsa05034", "KEGG:hsa05322", "KEGG:hsa05203" ]
[ "Alcoholism", "Systemic lupus erythematosus", "Viral carcinogenesis" ]
[]
[ [], [], [] ]
ABC-family proteins mediated transport
Alcoholism
Budding and maturation of HIV virion
Antimicrobial peptides
1
92335-GP1
GP1
92335
STRADA
[ "STE20 related adaptor alpha", "LYK5", "NY-BR-96", "PMSE", "STRAD alpha", "Stlk", "STE20-related kinase adapter protein alpha", "STE20-like pseudokinase", "STE20-related kinase adaptor alpha", "protein kinase LYK5" ]
[ "KEGG:hsa04152", "REACT:R-HSA-2428924", "REACT:R-HSA-74751", "REACT:R-HSA-112399", "KEGG:hsa04150", "REACT:R-HSA-165159", "REACT:R-HSA-109704", "REACT:R-HSA-109703", "REACT:R-HSA-74752", "REACT:R-HSA-162582" ]
[ "AMPK signaling pathway", "IGF1R signaling cascade", "Insulin receptor signalling cascade", "IRS-mediated signalling", "mTOR signaling pathway", "mTOR signalling", "PI3K Cascade", "PKB-mediated events", "Signaling by Insulin receptor", "Signal Transduction" ]
[]
[ [], [], [], [], [], [], [], [], [], [] ]
AMPK signaling pathway
Basal cell carcinoma
Carbon metabolism
Linoleic acid (LA) metabolism
0
55763-GP1
GP1
55763
EXOC1
[ "exocyst complex component 1", "BM-102", "SEC3", "SEC3L1", "SEC3P", "exocyst complex component 1", "SEC3-like 1", "exocyst complex component Sec3" ]
[ "REACT:R-HSA-5620920", "REACT:R-HSA-5617833", "REACT:R-HSA-264876", "REACT:R-HSA-199991", "REACT:R-HSA-392499", "REACT:R-HSA-1852241", "REACT:R-HSA-2980736", "REACT:R-HSA-5653656" ]
[ "Cargo trafficking to the periciliary membrane", "Cilium Assembly", "Insulin processing", "Membrane Trafficking", "Metabolism of proteins", "Organelle biogenesis and maintenance", "Peptide hormone metabolism", "Vesicle-mediated transport" ]
[]
[ [], [], [], [], [], [], [], [] ]
Antimicrobial peptides
Cargo trafficking to the periciliary membrane
Dilated cardiomyopathy
Carbon metabolism
1
79400-GP1
GP1
79400
NOX5
[ "NADPH oxidase 5", "NADPH oxidase 5" ]
[ "REACT:R-HSA-2262752", "REACT:R-HSA-3299685" ]
[ "Cellular responses to stress", "Detoxification of Reactive Oxygen Species" ]
[]
[ [], [] ]
Cellular responses to stress
Spliceosome
Rho GTPase cycle
Acrosome Reaction
0
3150-GP1
GP1
3150
HMGN1
[ "high mobility group nucleosome binding domain 1", "HMG14", "high-mobility group nucleosome binding 1" ]
[ "REACT:R-HSA-73894", "REACT:R-HSA-6782135", "KEGG:hsa05168", "REACT:R-HSA-5696398" ]
[ "DNA Repair", "Dual incision in TC-NER", "Herpes simplex infection", "Nucleotide Excision Repair" ]
[]
[ [], [], [], [] ]
G alpha (q) signalling events
ER to Golgi Anterograde Transport
DNA Repair
Intra-Golgi traffic
2
4976-GP1
GP1
4976
OPA1
[ "BERHS", "MGM1", "MTDPS14", "NPG", "NTG", "largeG", "mitochondrial dynamin-like GTPase", "optic atrophy protein 1" ]
[ "REACT:R-HSA-109581", "REACT:R-HSA-5357801", "REACT:R-HSA-169911" ]
[ "Apoptosis", "Programmed Cell Death", "Regulation of Apoptosis" ]
[]
[ [], [], [] ]
Apoptosis
Ca2+ activated K+ channels
Spliceosome
Insulin secretion
0
728405-GP1
GP1
728405
USP17L29
[]
[ "REACT:R-HSA-5688426", "REACT:R-HSA-392499", "REACT:R-HSA-597592", "REACT:R-HSA-5689880" ]
[ "Deubiquitination", "Metabolism of proteins", "Post-translational protein modification", "Ub-specific processing proteases" ]
[]
[ [], [], [], [] ]
Complex I biogenesis
Deubiquitination
Activation of GABAB receptors
Metal ion SLC transporters
1
55778-GP1
GP1
55778
ZNF839
[ "zinc finger protein 839", "C14orf131", "zinc finger protein 839" ]
[ "REACT:R-HSA-74160", "REACT:R-HSA-212436" ]
[ "Gene Expression", "Generic Transcription Pathway" ]
[]
[ [], [] ]
Herpes simplex infection
Gene Expression
Amine ligand-binding receptors
Acrosome Reaction
1
7139-GP1
GP1
7139
TNNT2
[ "troponin T2, cardiac type", "CMD1D", "CMH2", "CMPD2", "LVNC6", "RCM3", "TnTC", "cTnT", "troponin T, cardiac muscle", "troponin T type 2 (cardiac)", "truncated cardiac troponin T" ]
[ "KEGG:hsa04261", "KEGG:hsa04260", "KEGG:hsa05414", "REACT:R-HSA-397014", "REACT:R-HSA-390522" ]
[ "Adrenergic signaling in cardiomyocytes", "Cardiac muscle contraction", "Dilated cardiomyopathy", "Muscle contraction", "Striated Muscle Contraction" ]
[]
[ [], [], [], [], [] ]
Integration of energy metabolism
Arachidonic acid metabolism
Adrenergic signaling in cardiomyocytes
FGFR2 alternative splicing
2
23523-GP1
GP1
23523
CABIN1
[ "calcineurin binding protein 1", "CAIN", "KB-318B8.7", "PPP3IN", "calcineurin binding protein cabin 1", "calcineurin inhibitor" ]
[ "REACT:R-HSA-2262752", "REACT:R-HSA-2559583" ]
[ "Cellular responses to stress", "Cellular Senescence" ]
[]
[ [], [] ]
Influenza A
Cell Cycle
Cellular responses to stress
G alpha (s) signalling events
2
7844-GP1
GP1
7844
RNF103
[ "ring finger protein 103", "HKF-1", "KF-1", "KF1", "ZFP-103", "ZFP103", "zinc finger protein 103 homolog", "zinc finger protein expressed in cerebellum" ]
[ "REACT:R-HSA-901042", "REACT:R-HSA-392499", "REACT:R-HSA-597592" ]
[ "Calnexin/calreticulin cycle", "Metabolism of proteins", "Post-translational protein modification" ]
[]
[ [], [], [] ]
Dilated cardiomyopathy
ABC-family proteins mediated transport
Calnexin/calreticulin cycle
Endocytosis
2
55660-GP1
GP1
55660
PRPF40A
[ "FBP-11", "FBP11", "FLAF1", "FNBP3", "HIP-10", "HIP10", "HYPA", "NY-REN-6", "Prp40", "Fas-ligand associated factor 1", "Huntingtin-interacting protein A", "NY-REN-6 antigen", "fas ligand-associated factor 1", "formin binding protein 3", "formin-binding protein 11", "huntingtin yeast partner A", "huntingtin-interacting protein 10" ]
[ "REACT:R-HSA-74160", "REACT:R-HSA-72172", "REACT:R-HSA-72163", "KEGG:hsa03040" ]
[ "Gene Expression", "mRNA Splicing", "mRNA Splicing - Major Pathway", "Spliceosome" ]
[]
[ [], [], [], [] ]
Muscle contraction
Autophagy - animal
Gene Expression
G alpha (q) signalling events
2
390113-GP1
GP1
390113
OR4X1
[ "OR11-104", "olfactory receptor 4X1", "olfactory receptor OR11-104" ]
[ "REACT:R-HSA-388396", "REACT:R-HSA-381753", "KEGG:hsa04740", "REACT:R-HSA-372790", "REACT:R-HSA-162582" ]
[ "GPCR downstream signaling", "Olfactory Signaling Pathway", "Olfactory transduction", "Signaling by GPCR", "Signal Transduction" ]
[]
[ [], [], [], [], [] ]
Oocyte meiosis
GPCR downstream signaling
Gap junction
Mitophagy - animal
1
64216-GP1
GP1
64216
TFB2M
[ "transcription factor B2, mitochondrial", "Hkp1", "mtTFB2", "h-mtTFB", "h-mtTFB2", "hTFB2M", "mitochondrial 12S rRNA dimethylase 2", "mitochondrial transcription factor B2" ]
[ "REACT:R-HSA-74160", "REACT:R-HSA-1592230", "REACT:R-HSA-163282", "REACT:R-HSA-1852241", "REACT:R-HSA-2151201", "REACT:R-HSA-75944" ]
[ "Gene Expression", "Mitochondrial biogenesis", "Mitochondrial transcription initiation", "Organelle biogenesis and maintenance", "Transcriptional activation of mitochondrial biogenesis", "Transcription from mitochondrial promoters" ]
[]
[ [], [], [], [], [], [] ]
Gene Expression
Non-small cell lung cancer
Cul3-SPOP complex
Mitophagy - animal
0
2289-GP1
GP1
2289
FKBP5
[ "FKBP prolyl isomerase 5", "AIG6", "FKBP51", "FKBP54", "P54", "PPIase", "Ptg-10", "51 kDa FK506-binding protein", "51 kDa FKBP", "FF1 antigen", "FK506 binding protein 5", "FKBP-51", "HSP90-binding immunophilin", "PPIase FKBP5", "T-cell FK506-binding protein", "androgen-regulated protein 6", "rotamase" ]
[ "KEGG:hsa04915" ]
[ "Estrogen signaling pathway" ]
[]
[ [] ]
Cilium Assembly
Cell Cycle
Mineral absorption
Estrogen signaling pathway
3
5143-GP1
GP1
5143
PDE4C
[ "phosphodiesterase 4C", "DPDE1", "PDE21" ]
[ "KEGG:hsa04024", "REACT:R-HSA-180024", "REACT:R-HSA-418555", "REACT:R-HSA-388396", "KEGG:hsa05032", "REACT:R-HSA-111885", "KEGG:hsa00230", "REACT:R-HSA-372790", "REACT:R-HSA-162582" ]
[ "cAMP signaling pathway", "DARPP-32 events", "G alpha (s) signalling events", "GPCR downstream signaling", "Morphine addiction", "Opioid Signalling", "Purine metabolism", "Signaling by GPCR", "Signal Transduction" ]
[]
[ [], [], [], [], [], [], [], [], [] ]
Mineral absorption
Autophagy - animal
Biological oxidations
cAMP signaling pathway
3
314-GP1
GP1
314
AOC2
[ "amine oxidase copper containing 2", "DAO2", "RAO", "SSAO" ]
[ "KEGG:hsa00410", "REACT:R-HSA-211859", "KEGG:hsa01100", "REACT:R-HSA-1430728", "REACT:R-HSA-211945", "KEGG:hsa00360", "KEGG:hsa00350" ]
[ "beta-Alanine metabolism", "Biological oxidations", "Metabolic pathways", "Metabolism", "Phase 1 - Functionalization of compounds", "Phenylalanine metabolism", "Tyrosine metabolism" ]
[]
[ [], [], [], [], [], [], [] ]
Focal adhesion
Integration of energy metabolism
beta-Alanine metabolism
ABC-family proteins mediated transport
2
27089-GP1
GP1
27089
UQCRQ
[ "MC3DN4", "QCR8", "QP-C", "QPC", "UQCR7", "complex III subunit 8", "complex III subunit VIII" ]
[ "KEGG:hsa05010", "KEGG:hsa04260", "KEGG:hsa_M00152", "KEGG:hsa05016", "KEGG:hsa01100", "REACT:R-HSA-1430728", "KEGG:hsa00190", "KEGG:hsa05012", "REACT:R-HSA-611105" ]
[ "Alzheimer's disease", "Cardiac muscle contraction", "Cytochrome bc1 complex", "Huntington's disease", "Metabolic pathways", "Metabolism", "Oxidative phosphorylation", "Parkinson's disease", "Respiratory electron transport" ]
[]
[ [], [], [], [], [], [], [], [], [] ]
Gap junction
Alzheimer's disease
Transcriptional misregulation in cancer
Heme biosynthesis
1
54776-GP1
GP1
54776
PPP1R12C
[ "protein phosphatase 1 regulatory subunit 12C", "AAVS1", "LENG3", "MBS85", "p84", "p85", "protein phosphatase 1 regulatory subunit 12C", "myosin-binding subunit 85" ]
[ "KEGG:hsa04510", "KEGG:hsa04921", "KEGG:hsa05205", "KEGG:hsa04810", "KEGG:hsa04270" ]
[ "Focal adhesion", "Oxytocin signaling pathway", "Proteoglycans in cancer", "Regulation of actin cytoskeleton", "Vascular smooth muscle contraction" ]
[]
[ [], [], [], [], [] ]
G alpha (s) signalling events
Focal adhesion
Amoebiasis
RA biosynthesis pathway
1
1345-GP1
GP1
1345
COX6C
[ "epididymis secretory sperm binding protein" ]
[ "KEGG:hsa05010", "KEGG:hsa04260", "KEGG:hsa_M00154", "REACT:R-HSA-74160", "REACT:R-HSA-212436", "KEGG:hsa05016", "KEGG:hsa01100", "REACT:R-HSA-1430728", "KEGG:hsa00190", "KEGG:hsa05012", "REACT:R-HSA-611105", "REACT:R-HSA-5628897", "REACT:R-HSA-3700989" ]
[ "Alzheimer's disease", "Cardiac muscle contraction", "Cytochrome c oxidase", "Gene Expression", "Generic Transcription Pathway", "Huntington's disease", "Metabolic pathways", "Metabolism", "Oxidative phosphorylation", "Parkinson's disease", "Respiratory electron transport", "TP53 Regulates Metabolic Genes", "Transcriptional Regulation by TP53" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [] ]
Arachidonic acid metabolism
Phototransduction
Chemokine signaling pathway
Alzheimer's disease
3
80223-GP1
GP1
80223
RAB11FIP1
[ "RAB11 family interacting protein 1", "NOEL1A", "RCP", "rab11 family-interacting protein 1", "RAB11 coupling protein", "Rab effector protein", "Rab-interacting recycling protein" ]
[ "KEGG:hsa04144" ]
[ "Endocytosis" ]
[]
[ [] ]
Endocytosis
SNARE interactions in vesicular transport
Cul3-SPOP complex
MAPK signaling pathway
0
79370-GP1
GP1
79370
BCL2L14
[ "BCL2 like 14", "BCLG", "apoptosis regulator BCL-G", "testicular tissue protein Li 26" ]
[ "REACT:R-HSA-74160", "REACT:R-HSA-212436", "REACT:R-HSA-3700989" ]
[ "Gene Expression", "Generic Transcription Pathway", "Transcriptional Regulation by TP53" ]
[]
[ [], [], [] ]
G alpha (s) signalling events
ABC-family proteins mediated transport
Gene Expression
Influenza A
2
11171-GP1
GP1
11171
STRAP
[ "MAWD", "PT-WD", "UNRIP", "MAP activator with WD repeats", "MAPK activator with WD repeats", "WD-40 repeat protein PT-WD", "unr-interacting protein" ]
[ "KEGG:hsa03013", "REACT:R-HSA-162582", "KEGG:hsa_M00426" ]
[ "RNA transport", "Signal Transduction", "Survival motor neuron (SMN) complex" ]
[]
[ [], [], [] ]
GABA A receptor activation
Activation of HOX genes during differentiation
Cardiac conduction
RNA transport
3
5096-GP1
GP1
5096
PCCB
[ "PCCase subunit beta" ]
[ "REACT:R-HSA-196780", "KEGG:hsa01200", "REACT:R-HSA-3296482", "REACT:R-HSA-1643685", "REACT:R-HSA-5668914", "KEGG:hsa01100", "REACT:R-HSA-1430728", "KEGG:hsa00640", "REACT:R-HSA-71032" ]
[ "Biotin transport and metabolism", "Carbon metabolism", "Defects in vitamin and cofactor metabolism", "Disease", "Diseases of metabolism", "Metabolic pathways", "Metabolism", "Propanoate metabolism", "Propionyl-CoA catabolism" ]
[]
[ [], [], [], [], [], [], [], [], [] ]
Disease
Influenza A
Biotin transport and metabolism
G alpha (s) signalling events
2
221143-GP1
GP1
221143
EEF1AKMT1
[ "ESP13", "N6AMT2" ]
[ "REACT:R-HSA-392499", "REACT:R-HSA-597592", "REACT:R-HSA-8876725" ]
[ "Metabolism of proteins", "Post-translational protein modification", "Protein methylation" ]
[]
[ [], [], [] ]
IRE1alpha activates chaperones
Metabolism of proteins
African trypanosomiasis
Ovarian steroidogenesis
1
6898-GP1
GP1
6898
TAT
[ "tyrosine aminotransferase", "tyrosine aminotransferase", "testis tissue sperm-binding protein Li 34a" ]
[ "KEGG:hsa01230", "KEGG:hsa00270", "KEGG:hsa01100", "REACT:R-HSA-1430728", "REACT:R-HSA-71291", "KEGG:hsa_M00034", "KEGG:hsa00360", "KEGG:hsa00350" ]
[ "Biosynthesis of amino acids", "Cysteine and methionine metabolism", "Metabolic pathways", "Metabolism", "Metabolism of amino acids and derivatives", "Methionine salvage pathway", "Phenylalanine metabolism", "Tyrosine metabolism" ]
[]
[ [], [], [], [], [], [], [], [] ]
Adaptive Immune System
Autoimmune thyroid disease
Biosynthesis of amino acids
Ferroptosis
2
26574-GP1
GP1
26574
AATF
[ "apoptosis antagonizing transcription factor", "BFR2", "CHE-1", "CHE1", "DED", "protein AATF", "rb-binding protein Che-1" ]
[ "REACT:R-HSA-193648", "REACT:R-HSA-193704", "REACT:R-HSA-166520", "REACT:R-HSA-162582" ]
[ "NRAGE signals death through JNK", "p75 NTR receptor-mediated signalling", "Signalling by NGF", "Signal Transduction" ]
[]
[ [], [], [], [] ]
Integration of energy metabolism
Alcoholism
NRAGE signals death through JNK
Mitochondrial translation
2
545-GP1
GP1
545
ATR
[ "ATR serine/threonine kinase", "FCTCS", "FRP1", "MEC1", "SCKL", "SCKL1", "FRAP-related protein-1" ]
[ "REACT:R-HSA-176187", "KEGG:hsa04110", "REACT:R-HSA-1640170", "REACT:R-HSA-69620", "REACT:R-HSA-2262752", "REACT:R-HSA-3371556", "KEGG:hsa_M00691", "REACT:R-HSA-5693532", "REACT:R-HSA-73894", "KEGG:hsa03460", "REACT:R-HSA-6783310", "REACT:R-HSA-69481", "REACT:R-HSA-69473", "REACT:R-HSA-74160", "REACT:R-HSA-212436", "REACT:R-HSA-5693579", "REACT:R-HSA-5693538", "KEGG:hsa05166", "REACT:R-HSA-1500620", "REACT:R-HSA-1221632", "KEGG:hsa04115", "REACT:R-HSA-5693607", "REACT:R-HSA-3371453", "REACT:R-HSA-5633007", "REACT:R-HSA-3700989" ]
[ "Activation of ATR in response to replication stress", "Cell cycle", "Cell Cycle", "Cell Cycle Checkpoints", "Cellular responses to stress", "Cellular response to heat stress", "DNA damage-induced cell cycle checkpoints", "DNA Double-Strand Break Repair", "DNA Repair", "Fanconi anemia pathway", "Fanconi Anemia Pathway", "G2/M Checkpoints", "G2/M DNA damage checkpoint", "Gene Expression", "Generic Transcription Pathway", "Homologous DNA Pairing and Strand Exchange", "Homology Directed Repair", "HTLV-I infection", "Meiosis", "Meiotic synapsis", "p53 signaling pathway", "Processing of DNA double-strand break ends", "Regulation of HSF1-mediated heat shock response", "Regulation of TP53 Activity", "Transcriptional Regulation by TP53" ]
[]
[ [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [], [] ]
Oocyte meiosis
Bladder cancer
Dilated cardiomyopathy
Activation of ATR in response to replication stress
3
7114-GP1
GP1
7114
TMSB4X
[ "thymosin beta 4 X-linked", "FX", "PTMB4", "TB4X", "thymosin beta-4", "prothymosin beta-4", "t beta-4", "thymosin, beta 4, X chromosome" ]
[ "REACT:R-HSA-109582", "REACT:R-HSA-76002", "REACT:R-HSA-114608", "KEGG:hsa04810" ]
[ "Hemostasis", "Platelet activation, signaling and aggregation", "Platelet degranulation", "Regulation of actin cytoskeleton" ]
[]
[ [], [], [], [] ]
Ca2+ activated K+ channels
FGFR2 alternative splicing
Hemostasis
eNOS activation
2
91862-GP1
GP1
91862
MARVELD3
[ "MARVEL domain containing 3", "MARVD3", "MRVLDC3", "MARVEL domain-containing protein 3" ]
[ "KEGG:hsa04530" ]
[ "Tight junction" ]
[]
[ [] ]
Pyrimidine metabolism
Apoptosis - multiple species
Tight junction
Butanoate metabolism
2
54585-GP1
GP1
54585
LZTFL1
[ "leucine zipper transcription factor like 1", "BBS17", "leucine zipper transcription factor-like protein 1" ]
[ "REACT:R-HSA-5620920", "REACT:R-HSA-5617833", "REACT:R-HSA-1852241" ]
[ "Cargo trafficking to the periciliary membrane", "Cilium Assembly", "Organelle biogenesis and maintenance" ]
[]
[ [], [], [] ]
Autophagy - animal
Insulin resistance
Alpha-defensins
Cargo trafficking to the periciliary membrane
3