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effects of the administration of b663 [ g 30 320 , lamprene , clofazimine ( geigy ) ] on three groups of lepromatous and borderline of leprosy . | tradename_of | {
"id": "C0700047",
"name": "lamprene",
"pos": [
51,
59
]
} | {
"id": "C0008996",
"name": "clofazimine",
"pos": [
62,
73
]
} |
proceedings : the investigation of the fate of imferon ( iron-dextran ) following intra-peritoneal administration to iron-deficient children in zambia . | tradename_of | {
"id": "C0701986",
"name": "imferon",
"pos": [
47,
54
]
} | {
"id": "C0022092",
"name": "iron-dextran",
"pos": [
57,
69
]
} |
three times a week , durolax solution ( bisacodyl 10 mg in 5 ml of propylene glycol ) , usually 5 ml undiluted or diluted with 5 ml of tap water , is introduced into the rectum using a catheter and syringe . | tradename_of | {
"id": "C0591416",
"name": "durolax",
"pos": [
21,
28
]
} | {
"id": "C0005632",
"name": "bisacodyl",
"pos": [
40,
49
]
} |
further studies , both clinical and laboratory , disclosed that the responsible ingredient in this particular instance appeared to be the orange dye coating of the motrin-400 tablet rather than the ibuprofen itself . | tradename_of | {
"id": "C0699203",
"name": "motrin",
"pos": [
164,
170
]
} | {
"id": "C0020740",
"name": "ibuprofen",
"pos": [
198,
207
]
} |
six anephric subjects received kayexalate ( sodium polystyrene sulfonate ) during the studies to prevent potassium accumulation and increase in plasma potassium concentration . | tradename_of | {
"id": "C0124498",
"name": "kayexalate",
"pos": [
31,
41
]
} | {
"id": "C0142915",
"name": "sodium polystyrene sulfonate",
"pos": [
44,
72
]
} |
escherichia coli contains two l-asparaginase isozymes : a secreted high-affinity enzyme , l-asparaginase ii ( ansii ) , and a low-affinity cytoplasmic enzyme , l-asparaginase i ( ansi ) , which is encoded by the ansa gene . | tradename_of | {
"id": "C1510952",
"name": "l-asparaginase ii",
"pos": [
90,
107
]
} | {
"id": "C0003993",
"name": "l-asparaginase",
"pos": [
160,
174
]
} |
the advantages of vaseline occlusive dressing include greater patient comfort , the ability to evaluate the wound beneath the petroleum jelly , and the prevention of streaking , which can occur from uneven tape application . | tradename_of | {
"id": "C0728774",
"name": "vaseline",
"pos": [
18,
26
]
} | {
"id": "C0031262",
"name": "petroleum jelly",
"pos": [
126,
141
]
} |
the in vivo activity of augmentin ( amoxicillin + clavulanic acid ) , 1 g once or twice a day , during 10 +/- 3 days was evaluated on 10 cases urinary tract infections in paraplegic patients . | tradename_of | {
"id": "C0591132",
"name": "augmentin",
"pos": [
24,
33
]
} | {
"id": "C0054066",
"name": "amoxicillin",
"pos": [
36,
47
]
} |
three models of corneal inflammation -- acute toxic keratitis , phlyctenular keratitis and corneal graft rejection -- were induced in rabbits and treated with subconjunctival injections of antineoplastic agents ( methotrexate , cytosine arabinoside , 5-fluorouracil and 6-mercaptopurine ) and solu-medrol ( methylprednisolone sodium succinate ) . | tradename_of | {
"id": "C0701466",
"name": "solu-medrol",
"pos": [
293,
304
]
} | {
"id": "C0700546",
"name": "methylprednisolone sodium succinate",
"pos": [
307,
342
]
} |
providing low dose , continuous contraception for women . the norplant system utilizes silastic tubing filled with levonorgestrel . | tradename_of | {
"id": "C1145675",
"name": "norplant system",
"pos": [
62,
77
]
} | {
"id": "C0023566",
"name": "levonorgestrel",
"pos": [
115,
129
]
} |
anaesthesia was induced with 2 mg/kg propofol ( 'diprivan ' ) and maintained with a continuous infusion of propofol at a rate of 3 , 6 or 9 mg/kg/h randomly allocated . | tradename_of | {
"id": "C0678120",
"name": "diprivan",
"pos": [
49,
57
]
} | {
"id": "C0033487",
"name": "propofol",
"pos": [
107,
115
]
} |
lasix resulted in a significantly greater cumulative urinary excretion of furosemide than puresis and aquasin over the entire collection period . | tradename_of | {
"id": "C0699992",
"name": "lasix",
"pos": [
0,
5
]
} | {
"id": "C0016860",
"name": "furosemide",
"pos": [
74,
84
]
} |
following multiple-dose administration of either sustained-release indomethacin ( indocin sr ) or conventional indomethacin , drug accumulation is low . | tradename_of | {
"id": "C0700798",
"name": "indocin",
"pos": [
82,
89
]
} | {
"id": "C0021246",
"name": "indomethacin",
"pos": [
111,
123
]
} |
in order to compare tolerability and radiographic properties of omnipaque ( iohexol ) 350 mg i/ml and urografin ( sodium meglumine diatrizoate ) 76 % ( 370 mg i/ml ) in left ventriculography and coronary arteriography , a randomised , double-blind parallel study was conducted . | tradename_of | {
"id": "C0729203",
"name": "omnipaque",
"pos": [
64,
73
]
} | {
"id": "C0022005",
"name": "iohexol",
"pos": [
76,
83
]
} |
since the recent introduction of a drug regimen containing 2 mg of the antiandrogen cyproterone acetate and 50 micrograms ethinyl-oestradiol ( diane ; oestrogen-cyproterone acetate ) several uncontrolled reports have extolled the benefits of this drug . | tradename_of | {
"id": "C0057721",
"name": "diane",
"pos": [
143,
148
]
} | {
"id": "C0056855",
"name": "cyproterone acetate",
"pos": [
161,
180
]
} |
theo-24 ( g. d. searle & co. ) is an ultra-slow-absorbing formulation of theophylline suitable for once-a-day dosing in slow and normal metabolizers of theophylline . | tradename_of | {
"id": "C0700825",
"name": "theo-24",
"pos": [
0,
7
]
} | {
"id": "C0039771",
"name": "theophylline",
"pos": [
152,
164
]
} |
[ treatment of chronic myelosis with myleran ( myeleukon ) with special reference to alkaline leukocyte phosphatase activity ] . | tradename_of | {
"id": "C0700015",
"name": "myleran",
"pos": [
37,
44
]
} | {
"id": "C0006463",
"name": "myeleukon",
"pos": [
47,
56
]
} |
effect of chlordecone ( kepone ) on the rat brain concentration of 3-methoxy-4-hydroxyphenylglycol : evidence for a possible involvement of the norepinephrine system in chlordecone-induced tremor . | tradename_of | {
"id": "C0878176",
"name": "kepone",
"pos": [
24,
30
]
} | {
"id": "C0022562",
"name": "chlordecone",
"pos": [
169,
180
]
} |
90 % of the betnesol ( betamethasone sodium phosphate , benzalkonium chloride ) treated group were clinically judged cured compared with 68 % of the predsol ( prednisolone sodium phosphate , benzalkonium chloride ) treated group , and 57 % of the tolmetin treated group . | tradename_of | {
"id": "C0138279",
"name": "predsol",
"pos": [
149,
156
]
} | {
"id": "C0138273",
"name": "prednisolone sodium phosphate",
"pos": [
159,
188
]
} |
bezalip ( bezafibrate ) , at an oral dosage of 200 mg three times a day , has been used on 12 patients with idiopathic hyperlipidemia , and on 12 patients with hyperlipidemia superimposed with diabetes mellitus . | tradename_of | {
"id": "C0591179",
"name": "bezalip",
"pos": [
0,
7
]
} | {
"id": "C0005330",
"name": "bezafibrate",
"pos": [
10,
21
]
} |
in comparison to pilocarpine-eyedrops the ocusert-system has the following advantages : less pilocarpine-induced myopia and miosis , myopia and miosis extremely constant , minimal local side effects , reduced amount of drug release , almost no therapeutic discomfort for the patient , isolating the patient from the disease and good controlpossibility of the success of the treatment . | tradename_of | {
"id": "C0028870",
"name": "ocusert",
"pos": [
42,
49
]
} | {
"id": "C0031923",
"name": "pilocarpine",
"pos": [
93,
104
]
} |
monistat cream ( miconazole nitrate 2 % ) , a new fungicidal agent indicated for the treatment of vulvovaginal candidiasis , was evaluated in a comparative study with nystatin vaginal tablets ( 100 , -000 units each ) . | tradename_of | {
"id": "C1177005",
"name": "monistat",
"pos": [
0,
8
]
} | {
"id": "C0086620",
"name": "miconazole nitrate",
"pos": [
17,
35
]
} |
after careful study of the literature and other information available to it , the american cancer society does not have evidence that treatment with iscador , an extract of mistletoe , results in objective benefit in the treatment of cancer in human beings . | tradename_of | {
"id": "C0063891",
"name": "iscador",
"pos": [
149,
156
]
} | {
"id": "C1166209",
"name": "extract",
"pos": [
162,
169
]
} |
the effect of naproxen ( naprosyn ) on pain alleviation was studied in a double-blind cross-over trial using naproxen and placebo . | tradename_of | {
"id": "C0700017",
"name": "naprosyn",
"pos": [
25,
33
]
} | {
"id": "C0027396",
"name": "naproxen",
"pos": [
109,
117
]
} |
cytosar-u ( ara-c ) induced changes in mouse jejunal crypt epithelial kinetics and radiosensitivity to gamma rays and fast neutrons . | tradename_of | {
"id": "C0591320",
"name": "cytosar-u",
"pos": [
0,
9
]
} | {
"id": "C0010711",
"name": "ara-c",
"pos": [
12,
17
]
} |
they were allowed to drink [ 14c ] polyethylene glycol ( peg ) vivonex high nitrogen elemental diet ( vhn ) or intralipid fat emulsion ( il ) at 0.25 , 0.50 , and 1.00 kcal/ml under two conditions : drinking to satiety ( vhn ) or drinking to a constant volume of 15 ml ( vhn and il ) . | tradename_of | {
"id": "C0733854",
"name": "intralipid",
"pos": [
111,
121
]
} | {
"id": "C0304483",
"name": "fat emulsion",
"pos": [
122,
134
]
} |
physiological ( 0.9 % ) saline , usp , was used as the control , and intralipid 10 % fat emulsion ( vitrum , sweden ) as the reference article . | tradename_of | {
"id": "C0733854",
"name": "intralipid",
"pos": [
69,
79
]
} | {
"id": "C0304483",
"name": "fat emulsion",
"pos": [
85,
97
]
} |
as to adjuvant chemotherapy , the cooperative study group of surgical adjuvant chemotherapy for gastric cancer found in data on 1,805 patients followed for 5 years that the protocol , intraoperative bolus intravenous injection of mitomycin c ( mmc ) plus oral administration of futraful ( tegafur ) for 3 months , concomitantly applied with elx , proved to be effective for improving the survival of patients with advanced cancer such as stage iii and positive lymph node metastasis with obvious serosal invasion . | tradename_of | {
"id": "C0919261",
"name": "futraful",
"pos": [
278,
286
]
} | {
"id": "C0016778",
"name": "tegafur",
"pos": [
289,
296
]
} |
the tablets were quinaglute dura-tabs , manufactured by berlex laboratories , inc. , and generic quinidine gluconate tablets , manufactured by bolar pharmaceutical company . | tradename_of | {
"id": "C1097294",
"name": "quinaglute",
"pos": [
17,
27
]
} | {
"id": "C0072869",
"name": "quinidine gluconate",
"pos": [
97,
116
]
} |
immediate postabortal contraception with norplant : levonorgestrel , gonadotropin , estradiol , and progesterone levels over two postabortal months and return of fertility after removal of norplant capsules . | tradename_of | {
"id": "C1145675",
"name": "norplant",
"pos": [
41,
49
]
} | {
"id": "C0023566",
"name": "levonorgestrel",
"pos": [
52,
66
]
} |
two generic tablet formulations ( lasix and furix ) and intravenous furosemide were compared on 6 separate days . | tradename_of | {
"id": "C0699992",
"name": "lasix",
"pos": [
34,
39
]
} | {
"id": "C0016860",
"name": "furosemide",
"pos": [
68,
78
]
} |
the effect of tigason ( etretinate ) in the prevention of the recurrence of superficial bladder tumors ( ta-t1 , grade 0 papilloma and grade 1 and 2 carcinoma ) was studied in 30 patients in a double-blind , placebo-controlled study . | tradename_of | {
"id": "C0729231",
"name": "tigason",
"pos": [
14,
21
]
} | {
"id": "C0015137",
"name": "etretinate",
"pos": [
24,
34
]
} |
[ evaluation of the clinical effectiveness of cefobid ( cefoperazone sodium ) in the treatment of surgical infections ] . | tradename_of | {
"id": "C0733366",
"name": "cefobid",
"pos": [
46,
53
]
} | {
"id": "C0733367",
"name": "cefoperazone sodium",
"pos": [
56,
75
]
} |
among the pv patients , the erythrocyte enzyme activities were compared between 2 groups : patients treated solely with phlebotomy and patients treated with phlebotomy , myleran ( busulfan ) and/or radioactive phosphorus 32p . | tradename_of | {
"id": "C0700015",
"name": "myleran",
"pos": [
170,
177
]
} | {
"id": "C0006463",
"name": "busulfan",
"pos": [
180,
188
]
} |
the efficacy and tolerability of scopoderm tts ( scotts ) , a transdermal system containing scopolamine , were compared with those of the oral antiemetic dimenhydrinate ( double-dummy technique ) in a controlled , double-blind , within-patient study including 20 test persons with proven motion sickness . | tradename_of | {
"id": "C0729160",
"name": "scopoderm tts",
"pos": [
33,
46
]
} | {
"id": "C0036442",
"name": "scopolamine",
"pos": [
92,
103
]
} |
this phenotypic heterogeneity has been used here to study mechanisms associated with adriamycin ( doxorubicin hcl ) -induced cytotoxicity . | tradename_of | {
"id": "C0085752",
"name": "adriamycin",
"pos": [
85,
95
]
} | {
"id": "C0546861",
"name": "doxorubicin hcl",
"pos": [
98,
113
]
} |
an additional 37 patients weighing 76 +/- 19 kg received mean doses of 127 micrograms fentanyl plus 6.7 mg valium ( diazepam ; fv group ) . | tradename_of | {
"id": "C0699187",
"name": "valium",
"pos": [
107,
113
]
} | {
"id": "C0012010",
"name": "diazepam",
"pos": [
116,
124
]
} |
on each occasion , the subjects were fasted overnight on day 3 and were given an oral dose of inderal ( 40 mg propranolol hydrochloride ) 30 min following the administration of the morning dose of etintidine or placebo on day 4 . | tradename_of | {
"id": "C0591636",
"name": "inderal",
"pos": [
94,
101
]
} | {
"id": "C0282321",
"name": "propranolol hydrochloride",
"pos": [
110,
135
]
} |
the subdermal implantables ( norplant 2 or 5 ) release levonorgestrel out of a depot over a time period of at least 5 years . | tradename_of | {
"id": "C1145675",
"name": "norplant 2",
"pos": [
29,
39
]
} | {
"id": "C0023566",
"name": "levonorgestrel",
"pos": [
55,
69
]
} |
however , studies on the long-term intralipid clearance capacity have to be performed before any general recommendations about the inclusion of fat emulsions in parenteral nutrition of these patients can be made . | tradename_of | {
"id": "C0733854",
"name": "intralipid",
"pos": [
35,
45
]
} | {
"id": "C0304483",
"name": "fat emulsions",
"pos": [
144,
157
]
} |
visken ( pindolol ) , a blocking agent of adrenergic beta-receptors , was used in the treatment of hypertensive crisis in 30 patients ( stage i of the disease in 4 , stage ii in 23 , stage iii in 3 ) . | tradename_of | {
"id": "C0699962",
"name": "visken",
"pos": [
0,
6
]
} | {
"id": "C0031937",
"name": "pindolol",
"pos": [
9,
17
]
} |
ocusert is a system which releases a constant amount of pilocarpine over a period of seven days . | tradename_of | {
"id": "C0028870",
"name": "ocusert",
"pos": [
0,
7
]
} | {
"id": "C0031923",
"name": "pilocarpine",
"pos": [
56,
67
]
} |
reading were compared on a within patient basis for the following treatments : baseline control , after a single i.v . injection of 10 ml trental ( = 200 mg pentoxifylline ) and after 10 ml physiological saline solution ( = placebo ) . | tradename_of | {
"id": "C0699487",
"name": "trental",
"pos": [
138,
145
]
} | {
"id": "C0030899",
"name": "pentoxifylline",
"pos": [
157,
171
]
} |
[ the effects of pavulon ( pancuronium bromide ) on maternal circulation and metabolism as well as on fetal metabolism and postnatal condition at caesarean section ( author 's transl ) ] . | tradename_of | {
"id": "C0030715",
"name": "pavulon",
"pos": [
17,
24
]
} | {
"id": "C0030311",
"name": "pancuronium bromide",
"pos": [
27,
46
]
} |
in 39 patients the bioavailability of methotrexate from the two tablets emthexat 2.5 mg and methotrexate 2.5 mg was assessed in a double-blind study after a single oral dose of 30 mg/m2 methotrexate . | tradename_of | {
"id": "C1513200",
"name": "emthexat",
"pos": [
72,
80
]
} | {
"id": "C0025677",
"name": "methotrexate",
"pos": [
186,
198
]
} |
blood-contaminated omnipaque-300 ( winthrop-breon , new york , ny ) ( iohexol ) , isovue-300 ( e.r . squibb and sons , new brunswick , nj ) ( iopamidol ) , hexabrix ( mallinckrodt , st. louis , mo ) ( ioxaglate sodium meglumine ) , renografin-76 ( e.r . squibb and sons , new brunswick , nj ) ( diatrizoate sodium meglumine ) , and saline were studied in glass and plastic syringes ( 80 samples of each agent ) . | tradename_of | {
"id": "C0729203",
"name": "omnipaque",
"pos": [
19,
28
]
} | {
"id": "C0022005",
"name": "iohexol",
"pos": [
70,
77
]
} |
blood-contaminated omnipaque-300 ( winthrop-breon , new york , ny ) ( iohexol ) , isovue-300 ( e.r . squibb and sons , new brunswick , nj ) ( iopamidol ) , hexabrix ( mallinckrodt , st. louis , mo ) ( ioxaglate sodium meglumine ) , renografin-76 ( e.r . squibb and sons , new brunswick , nj ) ( diatrizoate sodium meglumine ) , and saline were studied in glass and plastic syringes ( 80 samples of each agent ) . | tradename_of | {
"id": "C0729210",
"name": "isovue",
"pos": [
82,
88
]
} | {
"id": "C0022026",
"name": "iopamidol",
"pos": [
142,
151
]
} |
norplant-2 contraceptive implants consist of two silastic rods in which levonorgestrel has been incorporated with the polymer . | tradename_of | {
"id": "C1145675",
"name": "norplant-2",
"pos": [
0,
10
]
} | {
"id": "C0023566",
"name": "levonorgestrel",
"pos": [
72,
86
]
} |
80 % of gram-negative , 98 % of gram-positive and 97 % of anaerobic isolates were susceptible to augmentin ( breakpoint 4 mg/l amoxicillin in the presence of 2.5 mg/l clavulanic acid ) . | tradename_of | {
"id": "C0591132",
"name": "augmentin",
"pos": [
97,
106
]
} | {
"id": "C0054066",
"name": "amoxicillin",
"pos": [
127,
138
]
} |
not only does it have a very high sensitivity and specificity for differentiating parenchymal from collecting system disease , but it also provides an accurate quantitative measurement of function and in combination with radioiodinated orthoiodohippurate renography and lasix ( furosemide ; abbott laboratories , north chicago ) diuresis will also differentiate significant obstruction from stasis . | tradename_of | {
"id": "C0699992",
"name": "lasix",
"pos": [
270,
275
]
} | {
"id": "C0016860",
"name": "furosemide",
"pos": [
278,
288
]
} |
the efficacy and safety of sequential parenteral-oral augmentin ( amoxicillin plus clavulanic acid ) therapy was evaluated in an open study with 249 adult patients in 18 swiss hospitals . | tradename_of | {
"id": "C0591132",
"name": "augmentin",
"pos": [
54,
63
]
} | {
"id": "C0054066",
"name": "amoxicillin",
"pos": [
66,
77
]
} |
all patients had postoperative combination chemotherapy : either with pa [ platinol ( bristol , uk ) and adriamycin ] or with chad ( cyclophosphamide , hexamethylmelamine , adriamycin and cis-diamminedichloroplatinum ) . | tradename_of | {
"id": "C0699666",
"name": "platinol",
"pos": [
75,
83
]
} | {
"id": "C0008838",
"name": "cis-diamminedichloroplatinum",
"pos": [
188,
216
]
} |
between february 1983 and january 1986 , the national cancer institute of canada conducted a prospective randomized trial comparing best supportive care ( bsc ) with two chemotherapy regimens : vindesine and cisplatin ( platinol ) ( vp ) and cyclophosphamide , doxorubicin , and cisplatin ( cap ) . | tradename_of | {
"id": "C0699666",
"name": "platinol",
"pos": [
220,
228
]
} | {
"id": "C0008838",
"name": "cisplatin",
"pos": [
279,
288
]
} |
the patient remains alive , with good neurological function and free of metastatic disease , 2 1/2 years following vertebrectomy , radiation therapy , and adjuvant provera ( medroxyprogesterone acetate ) therapy . | tradename_of | {
"id": "C0699702",
"name": "provera",
"pos": [
164,
171
]
} | {
"id": "C0065864",
"name": "medroxyprogesterone acetate",
"pos": [
174,
201
]
} |
the findings suggest that great investment in advertising is necessary in order to achieve high levels of sales for such drugs as valium ( diazepam ) which do not have a clear-cut ameliorative effect on a specific physiological condition . | tradename_of | {
"id": "C0699187",
"name": "valium",
"pos": [
130,
136
]
} | {
"id": "C0012010",
"name": "diazepam",
"pos": [
139,
147
]
} |
group i consisted of 138 patients who received premarin ( conjugated equine estrogen , ayerst ) in two different dosages ( 0.625 ; 1.25 mg ) and progestational agents such as neogest ( norgestrel , schering ) , duphaston ( dydrogesterone , duphar ) 5 mg and primolut n ( norethisterone , schering ) 5 mg , for a period ranging between 7 and 21 days . | tradename_of | {
"id": "C0699710",
"name": "premarin",
"pos": [
47,
55
]
} | {
"id": "C0014938",
"name": "conjugated",
"pos": [
58,
68
]
} |
group i consisted of 138 patients who received premarin ( conjugated equine estrogen , ayerst ) in two different dosages ( 0.625 ; 1.25 mg ) and progestational agents such as neogest ( norgestrel , schering ) , duphaston ( dydrogesterone , duphar ) 5 mg and primolut n ( norethisterone , schering ) 5 mg , for a period ranging between 7 and 21 days . | tradename_of | {
"id": "C0699168",
"name": "neogest",
"pos": [
175,
182
]
} | {
"id": "C0028368",
"name": "norgestrel",
"pos": [
185,
195
]
} |
steady state kinetic experiments show that clinoril ( sulindac sulphoxide ) acts as a non-competitive inhibitor of nadph oxidation with purified bovine lens aldose reductase , with an action that may involve binding to more than one site on the protein . | tradename_of | {
"id": "C0591267",
"name": "clinoril",
"pos": [
43,
51
]
} | {
"id": "C0038792",
"name": "sulindac sulphoxide",
"pos": [
54,
73
]
} |
as a preliminary to studying the effect on human lens and cataract , a double-masked , placebo-controlled study using random allocation into parallel groups was conducted on 20 volunteers to determine the penetration of clinoril ( sulindac ) and its metabolites into normal human red cells , and the effect of the drug on red cell nadph-oxidising activity . | tradename_of | {
"id": "C0591267",
"name": "clinoril",
"pos": [
220,
228
]
} | {
"id": "C0038792",
"name": "sulindac",
"pos": [
231,
239
]
} |
the arthrographic image quality and relative morbidity resulting from use of omnipaque 300 ( iohexol ) , hexabrix 320 ( ioxaglate sodium meglumine ) , and isopaque coronar 370 ( metrizoate ) were compared in a prospective double-blind study performed with 120 patients . | tradename_of | {
"id": "C0729203",
"name": "omnipaque",
"pos": [
77,
86
]
} | {
"id": "C0022005",
"name": "iohexol",
"pos": [
93,
100
]
} |
the monoclonal antibody , orthoclone okt3 ( okt3 ) , has been used with great efficacy in a prospective multicenter trial as therapy for first rejection episodes in cadaveric donor ( cd ) renal allograft recipients treated with azathioprine ( aza ) and prednisone ( p ) . | tradename_of | {
"id": "C0733466",
"name": "orthoclone okt3",
"pos": [
26,
41
]
} | {
"id": "C0085379",
"name": "okt3",
"pos": [
44,
48
]
} |
four members of the anesthetic and life support advisory committee of the food and drug administration assessed the contribution of isoflurane ( forane ) to 45 instances of hepatic dysfunction after isoflurane anesthesia reported to the fda for 1981-1984 . | tradename_of | {
"id": "C0306242",
"name": "forane",
"pos": [
145,
151
]
} | {
"id": "C0022180",
"name": "isoflurane",
"pos": [
199,
209
]
} |
a first group of five obese subjects ( 146 +/- 10 % of their ideal body weight [ ibw ] with normal glucose tolerance was submitted to a 75-g oral glucose tolerance test ( ogtt ) as a control and during an intralipid infusion ( 20 % fat emulsion , 1 ml/min , started 90 minutes prior to the glucose load ) . | tradename_of | {
"id": "C0733854",
"name": "intralipid",
"pos": [
205,
215
]
} | {
"id": "C0304483",
"name": "fat emulsion",
"pos": [
232,
244
]
} |
tegretol ( carbamazepine ) : a new and effective medical treatment of trigeminal neuralgia , with a note concerning its use in the syndrome of thalamic hyperpathia . | tradename_of | {
"id": "C0700087",
"name": "tegretol",
"pos": [
0,
8
]
} | {
"id": "C0006949",
"name": "carbamazepine",
"pos": [
11,
24
]
} |
effect of virazole ( ribavirin ) on tomato spotted wilt virus in two systemic hosts , tomato and tobacco . | tradename_of | {
"id": "C1622085",
"name": "virazole",
"pos": [
10,
18
]
} | {
"id": "C0035525",
"name": "ribavirin",
"pos": [
21,
30
]
} |
virazole ( 1 , beta-d-ribofuranosyl-1,2,4-triazole-3-carboxamide = ribavirin ) , a synthetic nucleoside analogue , has been successfully used against tomato spotted wilt virus ( tswv ) in tomato and tobacco plants . | tradename_of | {
"id": "C1622085",
"name": "virazole",
"pos": [
0,
8
]
} | {
"id": "C0035525",
"name": "ribavirin",
"pos": [
67,
76
]
} |
one-week tissue responses among the treated rabbits ranged from minimal to moderate for the progestasert intrauterine progesterone contraceptive system ( ipcs ) , placebo ( nonhormonal ) ipcs , lippes loop and saf-t-coil ; | tradename_of | {
"id": "C1515395",
"name": "progestasert",
"pos": [
92,
104
]
} | {
"id": "C0033308",
"name": "ipcs",
"pos": [
187,
191
]
} |
796 thai women who stopped using the long-acting injectable contraceptive 'depo-provera ' ( medroxyprogesterone acetate ) and 125 women who had an intra-uterine device removed to have a planned pregnancy were followed-up to ascertain the delay between conception and the end of contraception , and to determine the proportion of women who did not conceive in the 2 years after discontinuation . | tradename_of | {
"id": "C0699700",
"name": "depo-provera",
"pos": [
75,
87
]
} | {
"id": "C0065864",
"name": "medroxyprogesterone acetate",
"pos": [
92,
119
]
} |
comparative study on the results of consecutive dopaflex ( l-dopa ) and stereotactic surgical treatments in parkinsonism . | tradename_of | {
"id": "C1449995",
"name": "dopaflex",
"pos": [
48,
56
]
} | {
"id": "C0023570",
"name": "l-dopa",
"pos": [
59,
65
]
} |
the standard practice of using a single susceptibility disk for the antimicrobial combination septra ( trimethoprim/sulfamethoxazole ) has been further justified by a direct measurement of the diffusion rates of each compound through agar medium . | tradename_of | {
"id": "C0699595",
"name": "septra",
"pos": [
94,
100
]
} | {
"id": "C0041044",
"name": "trimethoprim/sulfamethoxazole",
"pos": [
103,
132
]
} |
thirteen patients were treated with busulphan ( myleran ) , of whom 12 showed varying degrees of responsiveness , and one was completely resistant both to busulphan and cyclophosphamide . | tradename_of | {
"id": "C0700015",
"name": "myleran",
"pos": [
48,
55
]
} | {
"id": "C0006463",
"name": "busulphan",
"pos": [
155,
164
]
} |
subcutaneous tumours in the flank of c3h mice anaesthetized with nembutal ( sodium pentobarbitol ) , valium ( diazepam ) , or urethane , were irradiated with doses of 1,500 or 2,500 rads and the delay in days for the tumours to grow from 4 to 10 mm in diameter was determined . | tradename_of | {
"id": "C0699187",
"name": "valium",
"pos": [
101,
107
]
} | {
"id": "C0012010",
"name": "diazepam",
"pos": [
110,
118
]
} |
the sensitivity of plasmodium falciparum strains to fansidar ( 500 mg sulphadoxine/25 mg pyrimethamine ) was tested in vivo in six localities in the united republic of tanzania where chloroquine-resistant p. falciparum strains have been demonstrated by both in vivo and in vitro tests . | tradename_of | {
"id": "C0060061",
"name": "fansidar",
"pos": [
52,
60
]
} | {
"id": "C0700599",
"name": "sulphadoxine",
"pos": [
70,
82
]
} |
thus , nocturnal dosing with uniphyl gives higher serum theophylline concentrations and , with this , better control of nocturnal asthma . | tradename_of | {
"id": "C0700814",
"name": "uniphyl",
"pos": [
29,
36
]
} | {
"id": "C0039771",
"name": "theophylline",
"pos": [
56,
68
]
} |
serum theophylline levels were measured in response to a single daily dose of uniphyl in asthmatic adults who had previously received sustained-release theophylline preparations ( usually theo-dur ) . | tradename_of | {
"id": "C0700814",
"name": "uniphyl",
"pos": [
78,
85
]
} | {
"id": "C0039771",
"name": "theophylline",
"pos": [
152,
164
]
} |
this study indicated that , in asthmatic patients previously receiving twice-daily theophylline therapy , switching to a daily single dose of uniphyl maintained stable blood levels with a very low incidence of side effects and a modest improvement to fev1 at the time of the normal serum peak of theophylline . | tradename_of | {
"id": "C0700814",
"name": "uniphyl",
"pos": [
142,
149
]
} | {
"id": "C0039771",
"name": "theophylline",
"pos": [
296,
308
]
} |
this study suggests that uniphyl can replace twice-daily theophylline dosing , which may result in improved patient compliance . | tradename_of | {
"id": "C0700814",
"name": "uniphyl",
"pos": [
25,
32
]
} | {
"id": "C0039771",
"name": "theophylline",
"pos": [
57,
69
]
} |
the objective assessment of danocrine ( danazol , winthrop ) in the treatment of endometriosis was hampered in the 1970s by the absence of a universally accepted classification . | tradename_of | {
"id": "C0813502",
"name": "danocrine",
"pos": [
28,
37
]
} | {
"id": "C0010961",
"name": "danazol",
"pos": [
40,
47
]
} |
the pharmacokinetics of four sustained-release formulations of theophylline have been examined after single doses ( nuelin sa , phyllocontin , slo-phyllin and theo-dur ) and at steady-state ( phyllocontin , theo-dur ) in six healthy adult volunteers , selected because they all eliminated theophylline rapidly after an intravenous dose of aminophylline . | tradename_of | {
"id": "C0722625",
"name": "phyllocontin",
"pos": [
128,
140
]
} | {
"id": "C0002575",
"name": "aminophylline",
"pos": [
339,
352
]
} |
classic examples are adriamycin ( doxorubicin hydrochloride ) and mitomycin c , but other less complex quinones also show effective antitumor activity . | tradename_of | {
"id": "C0085752",
"name": "adriamycin",
"pos": [
21,
31
]
} | {
"id": "C0546861",
"name": "doxorubicin hydrochloride",
"pos": [
34,
59
]
} |
pharmacokinetics of ( + ) - ( 2s,3s ) -2,3-dihydro-3-acetoxy-2- ( 4-methoxyphenyl ) -5- [ 2- ( dimethylamino ) ethyl ] -1,5-benzothiazepin-4 ( 5h ) -one hydrochloride ( diltiazem-hcl , cardizem , herbesser ) in rats and dogs were investigated using 14c-diltiazem-hcl . | tradename_of | {
"id": "C0700940",
"name": "cardizem",
"pos": [
185,
193
]
} | {
"id": "C0700579",
"name": "diltiazem-hcl",
"pos": [
253,
266
]
} |
the authors report 3 cases of temporary generalized lymphoadenopathy directly related to lamprene ( clofazimine ) consumption . | tradename_of | {
"id": "C0700047",
"name": "lamprene",
"pos": [
89,
97
]
} | {
"id": "C0008996",
"name": "clofazimine",
"pos": [
100,
111
]
} |
the influence of the local injection of hydrocortone ( compound f ) on the reactions to tuberculin , lepromin , frei and ducrey antigens . | tradename_of | {
"id": "C0699396",
"name": "hydrocortone",
"pos": [
40,
52
]
} | {
"id": "C0020268",
"name": "compound f",
"pos": [
55,
65
]
} |
the effect of phenergan ( promethazine hydrochloride ) on homografts of skin and thyroid in the guinea-pig . | tradename_of | {
"id": "C0591971",
"name": "phenergan",
"pos": [
14,
23
]
} | {
"id": "C0546876",
"name": "promethazine hydrochloride",
"pos": [
26,
52
]
} |
chlor-trimeton ( chlorprophenpyridamine maleate ) syrup was effective in preventing and controlling nausea and vomiting in 53 of 57 patients . | tradename_of | {
"id": "C0699075",
"name": "chlor-trimeton",
"pos": [
0,
14
]
} | {
"id": "C0546857",
"name": "chlorprophenpyridamine maleate",
"pos": [
17,
47
]
} |
myelography was performed in 30 patients using iohexol ( omnipaque ) 240 mg i/ml for lateral c1c2 injections , or iohexol 300 mg i/ml for lumbar injections . | tradename_of | {
"id": "C0729203",
"name": "omnipaque",
"pos": [
57,
66
]
} | {
"id": "C0022005",
"name": "iohexol",
"pos": [
114,
121
]
} |
structural variations in soluble iron complexes of models for ferritin : an x-ray absorption and mossbauer spectroscopy comparison of horse spleen ferritin to blutal ( iron-chondroitin sulfate ) and imferon ( iron-dextran ) . | tradename_of | {
"id": "C0701986",
"name": "imferon",
"pos": [
199,
206
]
} | {
"id": "C0022092",
"name": "iron-dextran",
"pos": [
209,
221
]
} |
this study was undertaken to assess the efficacy and safety of a 3-day course of treatment with mefoxitin ( cefoxitin sodium , msd ) in patients with perforated or ruptured appendicitis . | tradename_of | {
"id": "C0701380",
"name": "mefoxitin",
"pos": [
96,
105
]
} | {
"id": "C0700446",
"name": "cefoxitin sodium",
"pos": [
108,
124
]
} |
berotec ( 0.4 mg fenoterol hydrobromide , regimen b ) , atrovent ( 0.08 mg ipratropium bromide , regimen a ) and duovent ( 0.2 mg fenoterol hydrobromide and 0.08 mg ipratropium bromide , regimen d ) were administered by metered dose inhalers ( mdi ) to 12 patients with asthma ( regimens d and b only ) and 12 patients with chronic airflow obstruction ( cao ) . | tradename_of | {
"id": "C0591130",
"name": "atrovent",
"pos": [
56,
64
]
} | {
"id": "C0700580",
"name": "ipratropium bromide",
"pos": [
165,
184
]
} |
thin-layer chromatography ( tlc ) was used to confirm the alleged ingestion of loxitane ( loxapine succinate ) by a 20-month-old child . | tradename_of | {
"id": "C0700779",
"name": "loxitane",
"pos": [
79,
87
]
} | {
"id": "C0024057",
"name": "loxapine succinate",
"pos": [
90,
108
]
} |
three preparations of povidone-iodine were investigated : commercially available povidone-iodine solution betadine , pure high-molecular-weight povidone-iodine as used in betadine , and a low-molecular-weight povidone-iodine . | tradename_of | {
"id": "C0699524",
"name": "betadine",
"pos": [
106,
114
]
} | {
"id": "C0032857",
"name": "povidone-iodine",
"pos": [
209,
224
]
} |
physiological ( 0.9 % ) saline , usp , was used as the control , and intralipid 10 % fat emulsion as the reference article . | tradename_of | {
"id": "C0733854",
"name": "intralipid",
"pos": [
69,
79
]
} | {
"id": "C0304483",
"name": "fat emulsion",
"pos": [
85,
97
]
} |
l-keflex is a newly manufactured cephalexin product in order to maintain effective blood level of the drug for a long period of time . | tradename_of | {
"id": "C0700517",
"name": "keflex",
"pos": [
2,
8
]
} | {
"id": "C0007716",
"name": "cephalexin",
"pos": [
33,
43
]
} |
also , l-keflex has an advantage in that its administration frequence ( b.i.d ) is less than that of regular cephalexin ( q.i.d . ) . | tradename_of | {
"id": "C0700517",
"name": "keflex",
"pos": [
9,
15
]
} | {
"id": "C0007716",
"name": "cephalexin",
"pos": [
109,
119
]
} |
tolerance and haematological findings with antimalarials ( chloroquine and fansidar [ pyrimethamine plus sulfadoxine ] ) in adults and children during field trials in nigeria . | tradename_of | {
"id": "C0060061",
"name": "fansidar",
"pos": [
75,
83
]
} | {
"id": "C0700599",
"name": "pyrimethamine",
"pos": [
86,
99
]
} |
the antidepressant agent , stelazine ( trifluoroperazine dihydrochloride ) , is known to cause inactivation of the calcium-binding protein , calmodulin . | tradename_of | {
"id": "C0733842",
"name": "stelazine",
"pos": [
27,
36
]
} | {
"id": "C0304381",
"name": "trifluoroperazine dihydrochloride",
"pos": [
39,
72
]
} |
the recruitment of clathrin coats to the membrane opposite ligand-receptor clusters is sensitive to the calmodulin-directed drug stelazine ( trifluoperazine dihydrochloride ) . | tradename_of | {
"id": "C0733842",
"name": "stelazine",
"pos": [
129,
138
]
} | {
"id": "C0304381",
"name": "trifluoperazine dihydrochloride",
"pos": [
141,
172
]
} |
the sustained release effect of these microcapsules and oruvail , the representative commercial product of ketoprofen , was evaluated by the ph shift dissolution method and in beagle dogs , respectively . | tradename_of | {
"id": "C0591927",
"name": "oruvail",
"pos": [
56,
63
]
} | {
"id": "C0022635",
"name": "ketoprofen",
"pos": [
107,
117
]
} |
vibra-tabs ( doxycycline hyclate ) , inderal ( propranolol hydrochloride ) , and slow-k ( potassium chloride ) were compared for topical effects in the carlborg-densert cat esophagus model , the alphin-droppleman cat gastric mucosa model adapted for dog intestine , and the rabbit colon . | tradename_of | {
"id": "C0591636",
"name": "inderal",
"pos": [
37,
44
]
} | {
"id": "C0282321",
"name": "propranolol hydrochloride",
"pos": [
47,
72
]
} |
vibra-tabs ( doxycycline hyclate ) , inderal ( propranolol hydrochloride ) , and slow-k ( potassium chloride ) were compared for topical effects in the carlborg-densert cat esophagus model , the alphin-droppleman cat gastric mucosa model adapted for dog intestine , and the rabbit colon . | tradename_of | {
"id": "C0700918",
"name": "slow-k",
"pos": [
81,
87
]
} | {
"id": "C0032825",
"name": "potassium chloride",
"pos": [
90,
108
]
} |