PatentNumber
stringlengths 10
12
| Year
int64 1.98k
2.02k
| reactions
stringlengths 20
1.76k
| canonical_reactions
stringlengths 20
1.76k
|
|---|---|---|---|
US09447116B2 | 2,016 | COC(=O)C(O)c1c(C)nc2sc3c(c2c1I)CCCC3.O=C([O-])O.[Na+].[O-][Cl+3]([O-])([O-])O>C(OC(C)(C)C)(=O)C>COC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3 | COC(=O)C(O)c1c(C)nc2sc3c(c2c1I)CCCC3.O=C([O-])O.[Na+].[O-][Cl+3]([O-])([O-])O>C(OC(C)(C)C)(=O)C>COC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3 |
US09447116B2 | 2,016 | CC(=O)OC(C)(C)C.CCOC(=O)C(O)c1c(C)nc2sc3c(c2c1I)CCCC3.O=S(=O)(O)O>ClCCl>CCOC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3 | CC(=O)OC(C)(C)C.CCOC(=O)C(O)c1c(C)nc2sc3c(c2c1I)CCCC3.O=S(=O)(O)O>ClCCl>CCOC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3 |
US09447116B2 | 2,016 | COC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3.[Na+].[OH-]>O1CCCC1>Cc1nc2sc3c(c2c(I)c1C(OC(C)(C)C)C(=O)O)CCCC3 | COC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3.[Na+].[OH-]>O1CCCC1>Cc1nc2sc3c(c2c(I)c1C(OC(C)(C)C)C(=O)O)CCCC3 |
US09447116B2 | 2,016 | Cc1nc2sc3c(c2c(I)c1[C@@H](OC(C)(C)C)C(=O)N1C(=O)OC[C@H]1Cc1ccccc1)CCCC3.Cl.O.O=S([O-])[O-].OO.[Li+].[Na+].[Na+].[OH-]>O1CCCC1.O>Cc1nc2sc3c(c2c(I)c1[C@@H](OC(C)(C)C)C(=O)O)CCCC3 | Cc1nc2sc3c(c2c(I)c1[C@@H](OC(C)(C)C)C(=O)N1C(=O)OC[C@H]1Cc1ccccc1)CCCC3.Cl.O.O=S([O-])[O-].OO.[Li+].[Na+].[Na+].[OH-]>O1CCCC1.O>Cc1nc2sc3c(c2c(I)c1[C@@H](OC(C)(C)C)C(=O)O)CCCC3 |
US09447116B2 | 2,016 | Cc1nc2sc3c(c2c(I)c1[C@H](OC(C)(C)C)C(=O)N1C(=O)OC[C@H]1Cc1ccccc1)CCCC3.Cl.O.O=S([O-])[O-].OO.[Li+].[Na+].[Na+].[OH-]>O1CCCC1.O>Cc1nc2sc3c(c2c(I)c1[C@H](OC(C)(C)C)C(=O)O)CCCC3 | Cc1nc2sc3c(c2c(I)c1[C@H](OC(C)(C)C)C(=O)N1C(=O)OC[C@H]1Cc1ccccc1)CCCC3.Cl.O.O=S([O-])[O-].OO.[Li+].[Na+].[Na+].[OH-]>O1CCCC1.O>Cc1nc2sc3c(c2c(I)c1[C@H](OC(C)(C)C)C(=O)O)CCCC3 |
US09447116B2 | 2,016 | CCN(C(C)C)C(C)C.CN(C)C(On1nnc2ccccc21)=[N+](C)C.CO.Cc1nc2sc3c(c2c(I)c1[C@H](OC(C)(C)C)C(=O)O)CCCC3.F[P-](F)(F)(F)(F)F>ClCCl>COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3 | CCN(C(C)C)C(C)C.CN(C)C(On1nnc2ccccc21)=[N+](C)C.CO.Cc1nc2sc3c(c2c(I)c1[C@H](OC(C)(C)C)C(=O)O)CCCC3.F[P-](F)(F)(F)(F)F>ClCCl>COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3 |
US09447116B2 | 2,016 | BrB(Br)Br.COc1cc(Cl)ccc1B(O)O>ClCCl>OB(O)c1ccc(Cl)cc1O | BrB(Br)Br.COc1cc(Cl)ccc1B(O)O>ClCCl>OB(O)c1ccc(Cl)cc1O |
US09447116B2 | 2,016 | CC(C)(O)C(C)(C)O.OB(O)c1ccc(Cl)cc1O>ClCCl>CC1(C)OB(c2ccc(Cl)cc2O)OC1(C)C | CC(C)(O)C(C)(C)O.OB(O)c1ccc(Cl)cc1O>ClCCl>CC1(C)OB(c2ccc(Cl)cc2O)OC1(C)C |
US09447116B2 | 2,016 | CC(C)(O)C(C)(C)O.Cc1ccc(B(O)O)c(F)c1.Cc1ccc(S(=O)(=O)O)cc1.O>C(OCC)C>Cc1ccc(B2OC(C)(C)C(C)(C)O2)c(F)c1 | CC(C)(O)C(C)(C)O.Cc1ccc(B(O)O)c(F)c1.Cc1ccc(S(=O)(=O)O)cc1.O>C(OCC)C>Cc1ccc(B2OC(C)(C)C(C)(C)O2)c(F)c1 |
US09447116B2 | 2,016 | Cc1nc2sc3c(c2c(-c2cncnc2)c1C(OC(C)(C)C)C(=O)O)CCCC3>CO.ClCCl>Cc1nc2sc3c(c2c(-c2cncnc2)c1[C@H](OC(C)(C)C)C(=O)O)CCCC3 | Cc1nc2sc3c(c2c(-c2cncnc2)c1C(OC(C)(C)C)C(=O)O)CCCC3>CO.ClCCl>Cc1nc2sc3c(c2c(-c2cncnc2)c1[C@H](OC(C)(C)C)C(=O)O)CCCC3 |
US09447116B2 | 2,016 | C=CCOc1cc(C)ccc1C(=O)c1c(N)sc2c1CCCC2.CC(=O)Cl.CCOC(=O)C(=O)CC(C)=O>C(O)C>C=CCOc1cc(C)ccc1-c1c(C(=O)C(=O)OCC)c(C)nc2sc3c(c12)CCCC3.Cl | C=CCOc1cc(C)ccc1C(=O)c1c(N)sc2c1CCCC2.CC(=O)Cl.CCOC(=O)C(=O)CC(C)=O>C(O)C>C=CCOc1cc(C)ccc1-c1c(C(=O)C(=O)OCC)c(C)nc2sc3c(c12)CCCC3.Cl |
US09447116B2 | 2,016 | C=CCOc1cc(C)ccc1-c1c(C(=O)C(=O)OCC)c(C)nc2sc3c(c12)CCCC3.Cl.[BH4-].[Na+]>C(O)C>C=CCOc1cc(C)ccc1-c1c(C(O)C(=O)OCC)c(C)nc2sc3c(c12)CCCC3 | C=CCOc1cc(C)ccc1-c1c(C(=O)C(=O)OCC)c(C)nc2sc3c(c12)CCCC3.Cl.[BH4-].[Na+]>C(O)C>C=CCOc1cc(C)ccc1-c1c(C(O)C(=O)OCC)c(C)nc2sc3c(c12)CCCC3 |
US09447116B2 | 2,016 | C=CCOc1cc(C)ccc1-c1c(C(O)C(=O)OCC)c(C)nc2sc3c(c12)CCCC3.CCI>CC#N.[Ag]=O.[Ag-]=O>CCOC(C(=O)O)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1O)CCCC3 | C=CCOc1cc(C)ccc1-c1c(C(O)C(=O)OCC)c(C)nc2sc3c(c12)CCCC3.CCI>CC#N.[Ag]=O.[Ag-]=O>CCOC(C(=O)O)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1O)CCCC3 |
US09447116B2 | 2,016 | C=CCOc1cc(C)ccc1-c1c(C(OCC)C(=O)OCC)c(C)nc2sc3c(c12)CCCC3.CN1C(=O)CC(=O)N(C)C1=O>ClCCl>CCOC(=O)C(OCC)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1O)CCCC3 | C=CCOc1cc(C)ccc1-c1c(C(OCC)C(=O)OCC)c(C)nc2sc3c(c12)CCCC3.CN1C(=O)CC(=O)N(C)C1=O>ClCCl>CCOC(=O)C(OCC)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1O)CCCC3 |
US09447116B2 | 2,016 | CCOC(=O)C(OCC)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1O)CCCC3.[Na+].[OH-]>C(O)C.O1CCCC1>CCOC(C(=O)O)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1O)CCCC3 | CCOC(=O)C(OCC)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1O)CCCC3.[Na+].[OH-]>C(O)C.O1CCCC1>CCOC(C(=O)O)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1O)CCCC3 |
US09447116B2 | 2,016 | CCOC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3.Cl.O=C([O-])[O-].OB(O)c1ccc2scnc2c1.[Cs+].[Cs+].[Li+].[OH-]>O1CCOCC1.O.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2].C1COCC1>Cc1nc2sc3c(c2c(I)c1C(OC(C)(C)C)C(=O)O)CCCC3 | CCOC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3.Cl.O=C([O-])[O-].OB(O)c1ccc2scnc2c1.[Cs+].[Cs+].[Li+].[OH-]>O1CCOCC1.O.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2].C1COCC1>Cc1nc2sc3c(c2c(I)c1C(OC(C)(C)C)C(=O)O)CCCC3 |
US09447116B2 | 2,016 | CCN(C(C)C)C(C)C.COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3.O.OB(O)c1ccc(Cl)cc1>O1CCOCC1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[Pd]>COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(Cl)cc1)CCCC3 | CCN(C(C)C)C(C)C.COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3.O.OB(O)c1ccc(Cl)cc1>O1CCOCC1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[Pd]>COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(Cl)cc1)CCCC3 |
US09447116B2 | 2,016 | COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(Cl)cc1)CCCC3.[Na+].[OH-]>O1CCCC1>Cc1nc2sc3c(c2c(-c2ccc(Cl)cc2)c1[C@H](OC(C)(C)C)C(=O)O)CCCC3 | COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(Cl)cc1)CCCC3.[Na+].[OH-]>O1CCCC1>Cc1nc2sc3c(c2c(-c2ccc(Cl)cc2)c1[C@H](OC(C)(C)C)C(=O)O)CCCC3 |
US09447116B2 | 2,016 | COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3.OB(O)c1ccc(Cl)cc1F>>COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(Cl)cc1F)CCCC3 | COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3.OB(O)c1ccc(Cl)cc1F>>COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(Cl)cc1F)CCCC3 |
US09447116B2 | 2,016 | COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3.O.O=P([O-])([O-])[O-].OB(O)c1ccc(Cl)cc1O.[K+].[K+].[K+]>O1CCOCC1.[Pd+2].ClC1C=C[C-](P(C(C)(C)C)C(C)(C)C)C=1Cl.[C-]1(P(C(C)(C)C)C(C)(C)C)C=CC=C1.[Fe+2]>COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(Cl)cc1O)CCCC3 | COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3.O.O=P([O-])([O-])[O-].OB(O)c1ccc(Cl)cc1O.[K+].[K+].[K+]>O1CCOCC1.[Pd+2].ClC1C=C[C-](P(C(C)(C)C)C(C)(C)C)C=1Cl.[C-]1(P(C(C)(C)C)C(C)(C)C)C=CC=C1.[Fe+2]>COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(Cl)cc1O)CCCC3 |
US09447116B2 | 2,016 | COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3.Cc1ccc(B2OC(C)(C)C(C)(C)O2)c(F)c1>>Cc1ccc(-c2c([C@H](OC(C)(C)C)C(=O)O)c(C)nc3sc4c(c23)CCCC4)c(F)c1 | COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3.Cc1ccc(B2OC(C)(C)C(C)(C)O2)c(F)c1>>Cc1ccc(-c2c([C@H](OC(C)(C)C)C(=O)O)c(C)nc3sc4c(c23)CCCC4)c(F)c1 |
US09447116B2 | 2,016 | C=CCBr.CC(=O)c1ccc(C)cc1O.O=C([O-])[O-].[K+].[K+]>CN(C)C=O>C=CCOc1cc(C)ccc1C(C)=O | C=CCBr.CC(=O)c1ccc(C)cc1O.O=C([O-])[O-].[K+].[K+]>CN(C)C=O>C=CCOc1cc(C)ccc1C(C)=O |
US09447116B2 | 2,016 | C=CCOc1cc(C)ccc1C(C)=O.COC(OC)N(C)C>>C=CCOc1cc(C)ccc1C(=O)/C=C/N(C)C | C=CCOc1cc(C)ccc1C(C)=O.COC(OC)N(C)C>>C=CCOc1cc(C)ccc1C(=O)/C=C/N(C)C |
US09447116B2 | 2,016 | C=CCOc1cc(C)ccc1C(=O)/C=C/N(C)C.Cl.NO>CO>C=CCOc1cc(C)ccc1-c1ccno1 | C=CCOc1cc(C)ccc1C(=O)/C=C/N(C)C.Cl.NO>CO>C=CCOc1cc(C)ccc1-c1ccno1 |
US09447116B2 | 2,016 | C=CCOc1cc(C)ccc1C(=O)c1c(N)sc2c1CCCC2.CC(=O)Cl.CCOC(=O)C(=O)CC(C)=O>C(O)C>C=CCOc1cc(C)ccc1-c1c(C(=O)C(=O)OCC)c(C)nc2sc3c(c12)CCCC3.Cl | C=CCOc1cc(C)ccc1C(=O)c1c(N)sc2c1CCCC2.CC(=O)Cl.CCOC(=O)C(=O)CC(C)=O>C(O)C>C=CCOc1cc(C)ccc1-c1c(C(=O)C(=O)OCC)c(C)nc2sc3c(c12)CCCC3.Cl |
US09447116B2 | 2,016 | C=CCOc1cc(C)ccc1-c1c(C(=O)C(=O)OCC)c(C)nc2sc3c(c12)CCCC3.Cl.[BH4-].[Na+]>C(O)C>C=CCOc1cc(C)ccc1-c1c(C(O)C(=O)OCC)c(C)nc2sc3c(c12)CCCC3 | C=CCOc1cc(C)ccc1-c1c(C(=O)C(=O)OCC)c(C)nc2sc3c(c12)CCCC3.Cl.[BH4-].[Na+]>C(O)C>C=CCOc1cc(C)ccc1-c1c(C(O)C(=O)OCC)c(C)nc2sc3c(c12)CCCC3 |
US09447116B2 | 2,016 | C=CCOc1cc(C)ccc1-c1c(C(O)C(=O)OCC)c(C)nc2sc3c(c12)CCCC3.CC(=O)OC(C)(C)C.O=S(=O)(O)O>ClCCl>C=CCOc1cc(C)ccc1-c1c(C(OC(C)(C)C)C(=O)OCC)c(C)nc2sc3c(c12)CCCC3 | C=CCOc1cc(C)ccc1-c1c(C(O)C(=O)OCC)c(C)nc2sc3c(c12)CCCC3.CC(=O)OC(C)(C)C.O=S(=O)(O)O>ClCCl>C=CCOc1cc(C)ccc1-c1c(C(OC(C)(C)C)C(=O)OCC)c(C)nc2sc3c(c12)CCCC3 |
US09447116B2 | 2,016 | C=CCOc1cc(C)ccc1-c1c(C(OC(C)(C)C)C(=O)OCC)c(C)nc2sc3c(c12)CCCC3.CN1C(=O)CC(=O)N(C)C1=O>ClCCl.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[Pd]>CCOC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1O)CCCC3 | C=CCOc1cc(C)ccc1-c1c(C(OC(C)(C)C)C(=O)OCC)c(C)nc2sc3c(c12)CCCC3.CN1C(=O)CC(=O)N(C)C1=O>ClCCl.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[Pd]>CCOC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1O)CCCC3 |
US09447116B2 | 2,016 | CCOC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1O)CCCC3.[Na+].[OH-]>C(O)C.O1CCCC1>Cc1ccc(-c2c(C(OC(C)(C)C)C(=O)O)c(C)nc3sc4c(c23)CCCC4)c(O)c1 | CCOC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1O)CCCC3.[Na+].[OH-]>C(O)C.O1CCCC1>Cc1ccc(-c2c(C(OC(C)(C)C)C(=O)O)c(C)nc3sc4c(c23)CCCC4)c(O)c1 |
US09447116B2 | 2,016 | CC1(C)OB(c2ccc(C(F)(F)F)cc2)OC1(C)C.CCN(C(C)C)C(C)C.COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3>O1CCOCC1.C(OCC)(=O)C.O.C1C=CC([P]([Pd]([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1>COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(C(F)(F)F)cc1)CCCC3 | CC1(C)OB(c2ccc(C(F)(F)F)cc2)OC1(C)C.CCN(C(C)C)C(C)C.COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3>O1CCOCC1.C(OCC)(=O)C.O.C1C=CC([P]([Pd]([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1>COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(C(F)(F)F)cc1)CCCC3 |
US09447116B2 | 2,016 | COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(C(F)(F)F)cc1)CCCC3.[Na+].[OH-]>>Cc1nc2sc3c(c2c(-c2ccc(C(F)(F)F)cc2)c1[C@H](OC(C)(C)C)C(=O)O)CCCC3 | COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(C(F)(F)F)cc1)CCCC3.[Na+].[OH-]>>Cc1nc2sc3c(c2c(-c2ccc(C(F)(F)F)cc2)c1[C@H](OC(C)(C)C)C(=O)O)CCCC3 |
US09447116B2 | 2,016 | CC1(C)OB(c2ccc(N)cc2)OC1(C)C.COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3.O.O=C([O-])O.[Na+]>CN(C)C(=O)C.CC(C)([P](C(C)(C)C)([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)C(C)(C)C)C>COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(N)cc1)CCCC3 | CC1(C)OB(c2ccc(N)cc2)OC1(C)C.COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3.O.O=C([O-])O.[Na+]>CN(C)C(=O)C.CC(C)([P](C(C)(C)C)([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)C(C)(C)C)C>COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(N)cc1)CCCC3 |
US09447116B2 | 2,016 | COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(Br)cc1)CCCC3.[Na+].[OH-]>>Cc1nc2sc3c(c2c(-c2ccc(Br)cc2)c1[C@H](OC(C)(C)C)C(=O)O)CCCC3 | COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(Br)cc1)CCCC3.[Na+].[OH-]>>Cc1nc2sc3c(c2c(-c2ccc(Br)cc2)c1[C@H](OC(C)(C)C)C(=O)O)CCCC3 |
US09447116B2 | 2,016 | CC(=O)OC(C)(C)C.CCOC(=O)C(O)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1)CCOC3.O=C([O-])O.O=S(=O)(O)O.[Na+]>ClCCl>CCOC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1)CCOC3 | CC(=O)OC(C)(C)C.CCOC(=O)C(O)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1)CCOC3.O=C([O-])O.O=S(=O)(O)O.[Na+]>ClCCl>CCOC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1)CCOC3 |
US09447116B2 | 2,016 | CCOC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1)CCOC3.[Na+].[OH-]>C(O)C.O1CCCC1>Cc1ccc(-c2c(C(OC(C)(C)C)C(=O)O)c(C)nc3sc4c(c23)CCOC4)cc1 | CCOC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1)CCOC3.[Na+].[OH-]>C(O)C.O1CCCC1>Cc1ccc(-c2c(C(OC(C)(C)C)C(=O)O)c(C)nc3sc4c(c23)CCOC4)cc1 |
US09447104B2 | 2,016 | C1CCN2C[C@@H]3C[C@@H](CN4CCCC[C@H]34)[C@@H]2C1.CC(C)(C)OC(=O)N1CCCC1.Fc1ccc(F)c(Br)c1.[Li]C(C)CC.[NH4+].[OH-]>CC(OC)(C)C.[Cl-].[Cl-].[Zn+2].CC([O-])=O.CC([O-])=O.[Pd+2].P(C(C)(C)C)(C(C)(C)C)C(C)(C)C.[H+].[B-](F)(F)(F)F>CC(C)(C)OC(=O)N1CCC[C@@H]1c1cc(F)ccc1F | C1CCN2C[C@@H]3C[C@@H](CN4CCCC[C@@H]34)[C@H]2C1.CC(C)(C)OC(=O)N1CCCC1.Fc1ccc(F)c(Br)c1.[Li]C(C)CC.[NH4+].[OH-]>CC(OC)(C)C.[Cl-].[Cl-].[Zn+2].CC([O-])=O.CC([O-])=O.[Pd+2].P(C(C)(C)C)(C(C)(C)C)C(C)(C)C.[H+].[B-](F)(F)(F)F>CC(C)(C)OC(=O)N1CCC[C@@H]1c1cc(F)ccc1F |
US09447104B2 | 2,016 | CCCCO.CCN(C(C)C)C(C)C.Clc1ccn2nccc2n1.Fc1ccc(F)c([C@H]2CCCN2)c1>CCOC(C)=O>Fc1ccc(F)c([C@H]2CCCN2c2ccn3nccc3n2)c1 | CCCCO.CCN(C(C)C)C(C)C.Clc1ccn2nccc2n1.Fc1ccc(F)c([C@H]2CCCN2)c1>CCOC(C)=O>Fc1ccc(F)c([C@H]2CCCN2c2ccn3nccc3n2)c1 |
US09447104B2 | 2,016 | Fc1ccc(F)c([C@H]2CCCN2c2ccn3nccc3n2)c1.O=[N+]([O-])O>C(O)(C(F)(F)F)=O>O=[N+]([O-])c1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12 | Fc1ccc(F)c([C@H]2CCCN2c2ccn3nccc3n2)c1.O=[N+]([O-])O>C(O)(C(F)(F)F)=O>O=[N+]([O-])c1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12 |
US09447104B2 | 2,016 | CO.ClCCl.O=[N+]([O-])c1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.[Cl-].[NH4+]>C(Cl)Cl.[Zn]>Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12 | CO.ClCCl.O=[N+]([O-])c1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.[Cl-].[NH4+]>C(Cl)Cl.[Zn]>Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12 |
US09447104B2 | 2,016 | CCN(C(C)C)C(C)C.Cl.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(n1ccnc1)n1ccnc1.OC1CNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1CC(O)C1 | CCN(C(C)C)C(C)C.Cl.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(n1ccnc1)n1ccnc1.OC1CNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1CC(O)C1 |
US09447104B2 | 2,016 | O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1CC(O)C1.O=S(=O)(O)O>CO>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1CC(O)C1.O=S(=O)(O)O | O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1CC(O)C1.O=S(=O)(O)O>CO>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1CC(O)C1.O=S(=O)(O)O |
US09447104B2 | 2,016 | CO.Cl.O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1CC(O)C1>O1CCOCC1>Cl.O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1CC(O)C1 | CO.Cl.O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1CC(O)C1>O1CCOCC1>Cl.O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1CC(O)C1 |
US09447104B2 | 2,016 | CNC.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(n1ccnc1)n1ccnc1>C(Cl)Cl>CN(C)C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12 | CNC.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(n1ccnc1)n1ccnc1>C(Cl)Cl>CN(C)C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12 |
US09447104B2 | 2,016 | CN(C)C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.CO.Cl>O1CCOCC1>CN(C)C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.Cl | CN(C)C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.CO.Cl>O1CCOCC1>CN(C)C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.Cl |
US09447104B2 | 2,016 | CC(C)(C)N=C=O.CCN(C(C)C)C(C)C.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12>C(Cl)Cl>CC(C)(C)NC(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12 | CC(C)(C)N=C=O.CCN(C(C)C)C(C)C.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12>C(Cl)Cl>CC(C)(C)NC(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12 |
US09447104B2 | 2,016 | Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C=Nc1ccccc1>C(Cl)Cl>O=C(Nc1ccccc1)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12 | Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C=Nc1ccccc1>C(Cl)Cl>O=C(Nc1ccccc1)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12 |
US09447104B2 | 2,016 | O=C(Nc1ccccc1)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=S(=O)(O)O>CO>O=C(Nc1ccccc1)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=S(=O)(O)O | O=C(Nc1ccccc1)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=S(=O)(O)O>CO>O=C(Nc1ccccc1)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=S(=O)(O)O |
US09447104B2 | 2,016 | CC(C)C(=O)OC(=O)C(C)C.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.c1ccncc1>C(Cl)Cl>CC(C)C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12 | CC(C)C(=O)OC(=O)C(C)C.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.c1ccncc1>C(Cl)Cl>CC(C)C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12 |
US09447104B2 | 2,016 | CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.Cn1nc(C(=O)O)ccc1=O.F[P-](F)(F)(F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cccc(F)c3)nc12>CCOCC.CN(C=O)C>Cn1nc(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cccc(F)c4)nc23)ccc1=O | CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.Cn1nc(C(=O)O)ccc1=O.F[P-](F)(F)(F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cccc(F)c3)nc12>CCOCC.CN(C=O)C>Cn1nc(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cccc(F)c4)nc23)ccc1=O |
US09447104B2 | 2,016 | CC(C)(C)[Si](C)(C)O[C@@H](CCl)CC#N.COCCOC.Fc1cccc([Mg]Br)c1.[Na+].[OH-]>CC(OC)(C)C.[Cl-].[Na+].O.CCO>CC(C)(C)[Si](C)(C)O[C@H]1CN=C(c2cccc(F)c2)C1 | CC(C)(C)[Si](C)(C)O[C@@H](CCl)CC#N.COCCOC.Fc1cccc([Mg]Br)c1.[Na+].[OH-]>CC(OC)(C)C.[Cl-].[Na+].O.CCO>CC(C)(C)[Si](C)(C)O[C@H]1CN=C(c2cccc(F)c2)C1 |
US09447104B2 | 2,016 | CC(=O)O.CC(C)(C)[Si](C)(C)O[C@H]1CN=C(c2cccc(F)c2)C1.[BH4-].[Na+]>CO>O[C@H]1CN[C@@H](c2cccc(F)c2)C1 | CC(=O)O.CC(C)(C)[Si](C)(C)O[C@H]1CN=C(c2cccc(F)c2)C1.[BH4-].[Na+]>CO>O[C@H]1CN[C@@H](c2cccc(F)c2)C1 |
US09447104B2 | 2,016 | CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.ClCCl.O[C@H]1CN[C@@H](c2cccc(F)c2)C1>CN(C1C=CN=CC=1)C.C1COCC1>CC(C)(C)OC(=O)N1C[C@H](O)C[C@@H]1c1cccc(F)c1 | CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.ClCCl.O[C@H]1CN[C@@H](c2cccc(F)c2)C1>CN(C1C=CN=CC=1)C.C1COCC1>CC(C)(C)OC(=O)N1C[C@H](O)C[C@@H]1c1cccc(F)c1 |
US09447104B2 | 2,016 | CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21.CC(C)(C)OC(=O)N1C[C@H](O)C[C@@H]1c1cccc(F)c1.[Na+].[OH-]>C(Cl)Cl.[Cl-].[Na+].O>CC(C)(C)OC(=O)N1CC(=O)C[C@@H]1c1cccc(F)c1 | CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21.CC(C)(C)OC(=O)N1C[C@H](O)C[C@@H]1c1cccc(F)c1.[Na+].[OH-]>C(Cl)Cl.[Cl-].[Na+].O>CC(C)(C)OC(=O)N1CC(=O)C[C@@H]1c1cccc(F)c1 |
US09447104B2 | 2,016 | CC(C)(C)OC(=O)N1CC(F)(F)C[C@@H]1c1cccc(F)c1.Cl.[Na+].[OH-]>>Fc1cccc([C@H]2CC(F)(F)CN2)c1 | CC(C)(C)OC(=O)N1CC(F)(F)C[C@@H]1c1cccc(F)c1.Cl.[Na+].[OH-]>>Fc1cccc([C@H]2CC(F)(F)CN2)c1 |
US09447104B2 | 2,016 | CCN(C(C)C)C(C)C.Cl.Nc1cnn2ccc(N3CC(F)(F)C[C@@H]3c3cccc(F)c3)nc12.O=C(n1ccnc1)n1ccnc1.OC1CNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CC(F)(F)C[C@@H]3c3cccc(F)c3)nc12)N1CC(O)C1 | CCN(C(C)C)C(C)C.Cl.Nc1cnn2ccc(N3CC(F)(F)C[C@@H]3c3cccc(F)c3)nc12.O=C(n1ccnc1)n1ccnc1.OC1CNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CC(F)(F)C[C@@H]3c3cccc(F)c3)nc12)N1CC(O)C1 |
US09447104B2 | 2,016 | CCN(C(C)C)C(C)C.Cl.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12.O=C(n1ccnc1)n1ccnc1.OC1CNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12)N1CC(O)C1 | CCN(C(C)C)C(C)C.Cl.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12.O=C(n1ccnc1)n1ccnc1.OC1CNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12)N1CC(O)C1 |
US09447104B2 | 2,016 | O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12)N1CC(O)C1.O=S(=O)(O)O>CO>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12)N1CC(O)C1.O=S(=O)(O)O | O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12)N1CC(O)C1.O=S(=O)(O)O>CO>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12)N1CC(O)C1.O=S(=O)(O)O |
US09447104B2 | 2,016 | C1COCCN1.Nc1cnn2ccc(N3CCC[C@@H]3c3cccc(F)c3)nc12.O=C(n1ccnc1)n1ccnc1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cccc(F)c3)nc12)N1CCOCC1 | C1COCCN1.Nc1cnn2ccc(N3CCC[C@@H]3c3cccc(F)c3)nc12.O=C(n1ccnc1)n1ccnc1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cccc(F)c3)nc12)N1CCOCC1 |
US09447104B2 | 2,016 | CC(C)(C)OC(=O)N1CCCC1=O.Fc1cccc([Mg]Br)c1>C1COCC1>CC(C)(C)OC(=O)NCCCC(=O)c1cccc(F)c1 | CC(C)(C)OC(=O)N1CCCC1=O.Fc1cccc([Mg]Br)c1>C1COCC1>CC(C)(C)OC(=O)NCCCC(=O)c1cccc(F)c1 |
US09447104B2 | 2,016 | CCOCC.Cl.FB(F)F.Fc1cccc(C2=NCCC2)c1.[Li]C>C1COCC1.CCOC(C)=O.O>CC1(c2cccc(F)c2)CCCN1 | CCOCC.Cl.FB(F)F.Fc1cccc(C2=NCCC2)c1.[Li]C>C1COCC1.CCOC(C)=O.O>CC1(c2cccc(F)c2)CCCN1 |
US09447104B2 | 2,016 | CC1(c2cccc(F)c2)CCCN1c1ccn2ncc(N)c2n1.CCN(C(C)C)C(C)C.Cl.O=C(n1ccnc1)n1ccnc1.OC1CNC1>C(Cl)Cl>CC1(c2cccc(F)c2)CCCN1c1ccn2ncc(NC(=O)N3CC(O)C3)c2n1 | CC1(c2cccc(F)c2)CCCN1c1ccn2ncc(N)c2n1.CCN(C(C)C)C(C)C.Cl.O=C(n1ccnc1)n1ccnc1.OC1CNC1>C(Cl)Cl>CC1(c2cccc(F)c2)CCCN1c1ccn2ncc(NC(=O)N3CC(O)C3)c2n1 |
US09447104B2 | 2,016 | CCN(C(C)C)C(C)C.Cl.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)cc(Cl)c3)nc12.O=C(n1ccnc1)n1ccnc1.OC1CNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)cc(Cl)c3)nc12)N1CC(O)C1 | CCN(C(C)C)C(C)C.Cl.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)cc(Cl)c3)nc12.O=C(n1ccnc1)n1ccnc1.OC1CNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)cc(Cl)c3)nc12)N1CC(O)C1 |
US09447104B2 | 2,016 | CCN(C(C)C)C(C)C.Cl.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3C(F)F)nc12.O=C(n1ccnc1)n1ccnc1.OC1CNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3C(F)F)nc12)N1CC(O)C1 | CCN(C(C)C)C(C)C.Cl.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3C(F)F)nc12.O=C(n1ccnc1)n1ccnc1.OC1CNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3C(F)F)nc12)N1CC(O)C1 |
US09447104B2 | 2,016 | C1COCCN1.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(n1ccnc1)n1ccnc1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1CCOCC1 | C1COCCN1.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(n1ccnc1)n1ccnc1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1CCOCC1 |
US09447104B2 | 2,016 | Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(n1ccnc1)n1ccnc1.O[C@H]1CCNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1CC[C@H](O)C1 | Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(n1ccnc1)n1ccnc1.O[C@H]1CCNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1CC[C@H](O)C1 |
US09447104B2 | 2,016 | O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1CC[C@H](O)C1.O=S(=O)(O)O>CO>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1CC[C@H](O)C1.O=S(=O)(O)O | O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1CC[C@H](O)C1.O=S(=O)(O)O>CO>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1CC[C@H](O)C1.O=S(=O)(O)O |
US09447104B2 | 2,016 | COC1CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)C1.O=S(=O)(O)O>CO>COC1CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)C1.O=S(=O)(O)O | COC1CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)C1.O=S(=O)(O)O>CO>COC1CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)C1.O=S(=O)(O)O |
US09447104B2 | 2,016 | CC1(O)CN(C(c2ccccc2)c2ccccc2)C1.ClCCl.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(n1ccnc1)n1ccnc1>>CC1(O)CNC1.COC1CNC1.Cl | CC1(O)CN(C(c2ccccc2)c2ccccc2)C1.ClCCl.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(n1ccnc1)n1ccnc1>>CC1(O)CNC1.COC1CNC1.Cl |
US09447104B2 | 2,016 | CC1(O)CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)C1.O=S(=O)(O)O>CO>CC1(O)CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)C1.O=S(=O)(O)O | CC1(O)CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)C1.O=S(=O)(O)O>CO>CC1(O)CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)C1.O=S(=O)(O)O |
US09447104B2 | 2,016 | CC1(O)CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)C1.CO.Cl>O1CCOCC1>CC1(O)CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)C1.Cl | CC1(O)CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)C1.CO.Cl>O1CCOCC1>CC1(O)CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)C1.Cl |
US09447104B2 | 2,016 | CC1(O)CNC1.CCN(C(C)C)C(C)C.COC1CNC1.Cl.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12.O=C(n1ccnc1)n1ccnc1>C(Cl)Cl>CC1(O)CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4Cl)nc23)C1 | CC1(O)CNC1.CCN(C(C)C)C(C)C.COC1CNC1.Cl.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12.O=C(n1ccnc1)n1ccnc1>C(Cl)Cl>CC1(O)CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4Cl)nc23)C1 |
US09447104B2 | 2,016 | C[C@H]1CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4Cl)nc23)CCN1C(=O)OC(C)(C)C.Cl>>C[C@H]1CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4Cl)nc23)CCN1.Cl.Cl | C[C@H]1CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4Cl)nc23)CCN1C(=O)OC(C)(C)C.Cl>>C[C@H]1CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4Cl)nc23)CCN1.Cl.Cl |
US09447104B2 | 2,016 | CC(C)N1CCNCC1.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(n1ccnc1)n1ccnc1>C(Cl)Cl>CC(C)N1CCN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)CC1 | CC(C)N1CCNCC1.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(n1ccnc1)n1ccnc1>C(Cl)Cl>CC(C)N1CCN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)CC1 |
US09447104B2 | 2,016 | CN1CCN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)CC1.CO.Cl>O1CCOCC1>CN1CCN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)CC1.Cl | CN1CCN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)CC1.CO.Cl>O1CCOCC1>CN1CCN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)CC1.Cl |
US09447104B2 | 2,016 | C[C@H]1CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)CCN1C(=O)OC(C)(C)C.Cl>>C[C@H]1CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)CCN1.Cl.Cl | C[C@H]1CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)CCN1C(=O)OC(C)(C)C.Cl>>C[C@H]1CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)CCN1.Cl.Cl |
US09447104B2 | 2,016 | CCN(C(C)C)C(C)C.Cl.Nc1cnn2ccc(N3CCC[C@@H]3c3cccc(F)c3)nc12.O=C(n1ccnc1)n1ccnc1.OC1CNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cccc(F)c3)nc12)N1CC(O)C1 | CCN(C(C)C)C(C)C.Cl.Nc1cnn2ccc(N3CCC[C@@H]3c3cccc(F)c3)nc12.O=C(n1ccnc1)n1ccnc1.OC1CNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cccc(F)c3)nc12)N1CC(O)C1 |
US09447104B2 | 2,016 | CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.COC(=O)C1(C(=O)O)CC1.F[P-](F)(F)(F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12>CCOC(C)=O.CN(C=O)C>COC(=O)C1(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)CC1 | CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.COC(=O)C1(C(=O)O)CC1.F[P-](F)(F)(F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12>CCOC(C)=O.CN(C=O)C>COC(=O)C1(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)CC1 |
US09447104B2 | 2,016 | COC(=O)C1(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)CC1.Cl.O.[Li+].[OH-]>C1COCC1.CO.O.O>O=C(O)C1(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)CC1 | COC(=O)C1(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)CC1.Cl.O.[Li+].[OH-]>C1COCC1.CO.O.O>O=C(O)C1(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)CC1 |
US09447104B2 | 2,016 | Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)cc(Cl)c3)nc12.O=C(n1ccnc1)n1ccnc1.O[C@H]1CCNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)cc(Cl)c3)nc12)N1CC[C@H](O)C1 | Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)cc(Cl)c3)nc12.O=C(n1ccnc1)n1ccnc1.O[C@H]1CCNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)cc(Cl)c3)nc12)N1CC[C@H](O)C1 |
US09447104B2 | 2,016 | Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12.O=C(n1ccnc1)n1ccnc1.O[C@H]1CCNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12)N1CC[C@@H](O)C1 | Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12.O=C(n1ccnc1)n1ccnc1.O[C@H]1CCNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12)N1CC[C@@H](O)C1 |
US09447104B2 | 2,016 | CC(C)(C)OC(=O)N1CC(C(=O)O)C1.CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12>C(#N)C>CC(C)(C)OC(=O)N1CC(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4Cl)nc23)C1 | CC(C)(C)OC(=O)N1CC(C(=O)O)C1.CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12>C(#N)C>CC(C)(C)OC(=O)N1CC(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4Cl)nc23)C1 |
US09447104B2 | 2,016 | CC(C)(C)OC(=O)N1CC(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4Cl)nc23)C1.O=C(O)C(F)(F)F>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12)C1CNC1.O=C(O)C(F)(F)F | CC(C)(C)OC(=O)N1CC(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4Cl)nc23)C1.O=C(O)C(F)(F)F>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12)C1CNC1.O=C(O)C(F)(F)F |
US09447104B2 | 2,016 | CC(C)(C)OC(=O)N1CCC(C)(C(=O)O)CC1.CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12>CN(C=O)C>CC(C)(C)OC(=O)N1CCC(C)(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4Cl)nc23)CC1 | CC(C)(C)OC(=O)N1CCC(C)(C(=O)O)CC1.CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12>CN(C=O)C>CC(C)(C)OC(=O)N1CCC(C)(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4Cl)nc23)CC1 |
US09447104B2 | 2,016 | CC(C)(C)OC(=O)N1CCC(C)(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4Cl)nc23)CC1.Cl>O1CCOCC1>CC1(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4Cl)nc23)CCNCC1.Cl | CC(C)(C)OC(=O)N1CCC(C)(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4Cl)nc23)CC1.Cl>O1CCOCC1>CC1(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4Cl)nc23)CCNCC1.Cl |
US09447104B2 | 2,016 | CC(C)(O)C(=O)O.CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12>C(#N)C>CC(C)(O)C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12 | CC(C)(O)C(=O)O.CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12>C(#N)C>CC(C)(O)C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12 |
US09447104B2 | 2,016 | CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(O)C1(C(F)(F)F)CC1>CCOC(C)=O.CN(C=O)C>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)C1(C(F)(F)F)CC1 | CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(O)C1(C(F)(F)F)CC1>CCOC(C)=O.CN(C=O)C>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)C1(C(F)(F)F)CC1 |
US09447104B2 | 2,016 | CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(O)c1cnccn1>CCOC(C)=O.CN(C=O)C>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)c1cnccn1 | CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(O)c1cnccn1>CCOC(C)=O.CN(C=O)C>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)c1cnccn1 |
US09447104B2 | 2,016 | CO.Cc1cccnc1C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.Cl>O1CCOCC1>Cc1cccnc1C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.Cl | CO.Cc1cccnc1C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.Cl>O1CCOCC1>Cc1cccnc1C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.Cl |
US09447104B2 | 2,016 | CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(O)c1ncccn1>CS(C)=O.CCOC(C)=O.CN(C=O)C>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)c1ncccn1 | CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(O)c1ncccn1>CS(C)=O.CCOC(C)=O.CN(C=O)C>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)c1ncccn1 |
US09447104B2 | 2,016 | Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(O)c1cccc(Cl)n1>>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)c1cccc(Cl)n1 | Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(O)c1cccc(Cl)n1>>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)c1cccc(Cl)n1 |
US09447104B2 | 2,016 | CO.COc1cccc(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cccc(F)c4)nc23)n1.Cl>O1CCOCC1>COc1cccc(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cccc(F)c4)nc23)n1.Cl | CO.COc1cccc(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cccc(F)c4)nc23)n1.Cl>O1CCOCC1>COc1cccc(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cccc(F)c4)nc23)n1.Cl |
US09447104B2 | 2,016 | CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cccc(F)c3)nc12.O=C(O)c1cccnc1>CCOC(C)=O.CN(C=O)C>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cccc(F)c3)nc12)c1cccnc1 | CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cccc(F)c3)nc12.O=C(O)c1cccnc1>CCOC(C)=O.CN(C=O)C>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cccc(F)c3)nc12)c1cccnc1 |
US09447104B2 | 2,016 | Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12.O=C(n1ccnc1)n1ccnc1.O[C@H]1CCNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12)N1CC[C@H](O)C1 | Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12.O=C(n1ccnc1)n1ccnc1.O[C@H]1CCNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12)N1CC[C@H](O)C1 |
US09447104B2 | 2,016 | CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.Cc1cnc(C(=O)O)cn1.F[P-](F)(F)(F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cccc(F)c3)nc12>CCOCC.CN(C=O)C>Cc1cnc(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cccc(F)c4)nc23)cn1 | CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.Cc1cnc(C(=O)O)cn1.F[P-](F)(F)(F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cccc(F)c3)nc12>CCOCC.CN(C=O)C>Cc1cnc(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cccc(F)c4)nc23)cn1 |
US09447104B2 | 2,016 | CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.Cn1ccnc1C(=O)O.F[P-](F)(F)(F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cccc(F)c3)nc12>CCOC(C)=O.CN(C=O)C>Cn1ccnc1C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cccc(F)c3)nc12 | CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.Cn1ccnc1C(=O)O.F[P-](F)(F)(F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cccc(F)c3)nc12>CCOC(C)=O.CN(C=O)C>Cn1ccnc1C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cccc(F)c3)nc12 |
US09447104B2 | 2,016 | Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3C(F)(F)F)nc12.O=C(n1ccnc1)n1ccnc1.O[C@H]1CCNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3C(F)(F)F)nc12)N1CC[C@H](O)C1 | Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3C(F)(F)F)nc12.O=C(n1ccnc1)n1ccnc1.O[C@H]1CCNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3C(F)(F)F)nc12)N1CC[C@H](O)C1 |
US09447104B2 | 2,016 | Nc1cnn2ccc(N3CCC[C@@H]3c3cncc(F)c3)nc12.O=C(n1ccnc1)n1ccnc1.O[C@H]1CCNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cncc(F)c3)nc12)N1CC[C@H](O)C1 | Nc1cnn2ccc(N3CCC[C@@H]3c3cncc(F)c3)nc12.O=C(n1ccnc1)n1ccnc1.O[C@H]1CCNC1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cncc(F)c3)nc12)N1CC[C@H](O)C1 |
US09447104B2 | 2,016 | CCN(C(C)C)C(C)C.COc1ccc(F)cc1[C@H]1CCCN1c1ccn2ncc(N)c2n1.O=C(n1ccnc1)n1ccnc1.O[C@H]1CCNC1>C(Cl)Cl>COc1ccc(F)cc1[C@H]1CCCN1c1ccn2ncc(NC(=O)N3CC[C@H](O)C3)c2n1 | CCN(C(C)C)C(C)C.COc1ccc(F)cc1[C@H]1CCCN1c1ccn2ncc(N)c2n1.O=C(n1ccnc1)n1ccnc1.O[C@H]1CCNC1>C(Cl)Cl>COc1ccc(F)cc1[C@H]1CCCN1c1ccn2ncc(NC(=O)N3CC[C@H](O)C3)c2n1 |
US09447104B2 | 2,016 | C1O[C@@H]2CN[C@H]1C2.CCN(C(C)C)C(C)C.Cl.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(n1ccnc1)n1ccnc1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1C[C@@H]2C[C@H]1CO2 | C1O[C@@H]2CN[C@H]1C2.CCN(C(C)C)C(C)C.Cl.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(n1ccnc1)n1ccnc1>C(Cl)Cl>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1C[C@@H]2C[C@H]1CO2 |
US09447104B2 | 2,016 | CCN(C(C)C)C(C)C.CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(O)[C@H]1CC[C@@H](O)C1>CC(N(C)C)=O>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)[C@H]1CC[C@@H](O)C1 | CCN(C(C)C)C(C)C.CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C(O)[C@H]1CC[C@@H](O)C1>CC(N(C)C)=O>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)[C@H]1CC[C@@H](O)C1 |