PatentNumber
stringlengths 10
12
| Year
int64 1.98k
2.02k
| reactions
stringlengths 20
1.76k
| canonical_reactions
stringlengths 20
1.76k
|
|---|---|---|---|
US09447104B2 | 2,016 | CCN(C(C)C)C(C)C.CNC.COC(=O)C(=O)Cl.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12>C(Cl)Cl>CN(C)C(=O)C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12 | CCN(C(C)C)C(C)C.CNC.COC(=O)C(=O)Cl.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12>C(Cl)Cl>CN(C)C(=O)C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12 |
US09447104B2 | 2,016 | CCN(C(C)C)C(C)C.COC(=O)C(=O)Cl.ClCCl.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12>>COC(=O)C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12 | CCN(C(C)C)C(C)C.COC(=O)C(=O)Cl.ClCCl.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12>>COC(=O)C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12 |
US09447104B2 | 2,016 | COC(=O)C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O.[Li]O>C1COCC1.CO.O>O=C(O)C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12 | COC(=O)C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O.[Li]O>C1COCC1.CO.O>O=C(O)C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12 |
US09447118B2 | 2,016 | CC1(C)C(=O)N(Br)C(=O)N1Br.CCOC(C)=O.C[C@@H](N)c1ccccc1.O=C(O)[C@@H]1CC=CCC1.O=S([O-])([O-])=S.[Na+].[Na+]>C(#N)C>O=C1O[C@H]2C[C@@H]1CC[C@@H]2Br | CC1(C)C(=O)N(Br)C(=O)N1Br.CCOC(C)=O.C[C@@H](N)c1ccccc1.O=C(O)[C@@H]1CC=CCC1.O=S([O-])([O-])=S.[Na+].[Na+]>C(#N)C>O=C1O[C@H]2C[C@@H]1CC[C@@H]2Br |
US09447118B2 | 2,016 | CNC.O=C(O)CC(O)(CC(=O)O)C(=O)O.O=C1O[C@H]2C[C@@H]1CC[C@@H]2Br>C(OCC)(=O)C>CN(C)C(=O)[C@H]1CC[C@H](Br)[C@@H](O)C1 | CNC.O=C(O)CC(O)(CC(=O)O)C(=O)O.O=C1O[C@H]2C[C@@H]1CC[C@@H]2Br>C(OCC)(=O)C>CN(C)C(=O)[C@H]1CC[C@H](Br)[C@@H](O)C1 |
US09447118B2 | 2,016 | CN(C)C(=O)[C@H]1CC[C@H](Br)[C@@H](O)C1.[Na+].[OH-]>C(Cl)Cl>CN(C)C(=O)[C@H]1CC[C@H]2O[C@H]2C1 | CN(C)C(=O)[C@H]1CC[C@H](Br)[C@@H](O)C1.[Na+].[OH-]>C(Cl)Cl>CN(C)C(=O)[C@H]1CC[C@H]2O[C@H]2C1 |
US09447118B2 | 2,016 | CN(C)C(=O)[C@H]1CC[C@H](Br)[C@@H](O)C1.[NH4+].[Na+].[OH-].[OH-]>>CN(C)C(=O)[C@H]1CC[C@@H](O)[C@H](N)C1 | CN(C)C(=O)[C@H]1CC[C@H](Br)[C@@H](O)C1.[NH4+].[Na+].[OH-].[OH-]>>CN(C)C(=O)[C@H]1CC[C@@H](O)[C@H](N)C1 |
US09447118B2 | 2,016 | CN(C)C(=O)[C@H]1CC[C@H](Br)[C@@H](O)C1.[NH4+].[OH-]>>CN(C)C(=O)[C@H]1CC[C@@H](O)[C@H](N)C1 | CN(C)C(=O)[C@H]1CC[C@H](Br)[C@@H](O)C1.[NH4+].[OH-]>>CN(C)C(=O)[C@H]1CC[C@@H](O)[C@H](N)C1 |
US09447118B2 | 2,016 | CCOC(C)=O.CNC.O=C(O)CC(O)(CC(=O)O)C(=O)O.O=C1O[C@H]2C[C@@H]1CC[C@@H]2Br>O>CN(C)C(=O)[C@H]1CC[C@H](Br)[C@@H](O)C1 | CCOC(C)=O.CNC.O=C(O)CC(O)(CC(=O)O)C(=O)O.O=C1O[C@H]2C[C@@H]1CC[C@@H]2Br>O>CN(C)C(=O)[C@H]1CC[C@H](Br)[C@@H](O)C1 |
US09447118B2 | 2,016 | CN1CCc2nc(C(=O)N[C@@H]3C[C@@H](C(=O)N(C)C)CC[C@@H]3NC(=O)C(=O)Nc3ccc(Cl)cn3)sc2C1.Cc1ccc(S(=O)(=O)O)cc1>C(Cl)Cl.C(O)C>CN1CCc2nc(C(=O)N[C@@H]3C[C@@H](C(=O)N(C)C)CC[C@@H]3NC(=O)C(=O)Nc3ccc(Cl)cn3)sc2C1.Cc1ccc(S(=O)(=O)O)cc1.O | CN1CCc2nc(C(=O)N[C@@H]3C[C@@H](C(=O)N(C)C)CC[C@@H]3NC(=O)C(=O)Nc3ccc(Cl)cn3)sc2C1.Cc1ccc(S(=O)(=O)O)cc1>C(Cl)Cl.C(O)C>CN1CCc2nc(C(=O)N[C@@H]3C[C@@H](C(=O)N(C)C)CC[C@@H]3NC(=O)C(=O)Nc3ccc(Cl)cn3)sc2C1.Cc1ccc(S(=O)(=O)O)cc1.O |
US09447118B2 | 2,016 | CCN(CC)CC.CN(C)C(=O)[C@H]1CC[C@@H](O)[C@H](NS(=O)(=O)NC(=O)OC(C)(C)C)C1.CS(=O)(=O)Cl.O>C(#N)C>CN(C)C(=O)[C@H]1CC[C@@H](OS(C)(=O)=O)[C@H](NS(=O)(=O)NC(=O)OC(C)(C)C)C1 | CCN(CC)CC.CN(C)C(=O)[C@H]1CC[C@@H](O)[C@H](NS(=O)(=O)NC(=O)OC(C)(C)C)C1.CS(=O)(=O)Cl.O>C(#N)C>CN(C)C(=O)[C@H]1CC[C@@H](OS(C)(=O)=O)[C@H](NS(=O)(=O)NC(=O)OC(C)(C)C)C1 |
US09447118B2 | 2,016 | CN(C)C(=O)[C@H]1CC[C@@H](O)[C@H](NS(=O)(=O)NC(=O)OC(C)(C)C)C1.CN1CCOCC1.CS(=O)(=O)Cl.Cl>C(#N)C.O>CN(C)C(=O)[C@H]1CC[C@@H](OS(C)(=O)=O)[C@H](NS(=O)(=O)NC(=O)OC(C)(C)C)C1 | CN(C)C(=O)[C@H]1CC[C@@H](O)[C@H](NS(=O)(=O)NC(=O)OC(C)(C)C)C1.CN1CCOCC1.CS(=O)(=O)Cl.Cl>C(#N)C.O>CN(C)C(=O)[C@H]1CC[C@@H](OS(C)(=O)=O)[C@H](NS(=O)(=O)NC(=O)OC(C)(C)C)C1 |
US09447118B2 | 2,016 | CN(C)C(=O)[C@H]1CC[C@@H](O)[C@H](NS(=O)(=O)NC(=O)OCc2ccccc2)C1.CS(=O)(=O)Cl.ClCCl>C(N(CC)CC)C>CN(C)C(=O)[C@H]1CC[C@@H](OS(C)(=O)=O)[C@H](NS(=O)(=O)NC(=O)OCc2ccccc2)C1 | CN(C)C(=O)[C@H]1CC[C@@H](O)[C@H](NS(=O)(=O)NC(=O)OCc2ccccc2)C1.CS(=O)(=O)Cl.ClCCl>C(N(CC)CC)C>CN(C)C(=O)[C@H]1CC[C@@H](OS(C)(=O)=O)[C@H](NS(=O)(=O)NC(=O)OCc2ccccc2)C1 |
US09447118B2 | 2,016 | CN(C)C(=O)[C@H]1CC[C@@H](O)[C@H](NS(=O)(=O)NC(=O)OC(C)(C)C)C1.Cc1ccc(S(=O)(=O)Cl)cc1.Cn1ccnc1>ClCCl>Cc1ccc(S(=O)(=O)O[C@@H]2CC[C@H](C(=O)N(C)C)C[C@H]2NS(=O)(=O)NC(=O)OC(C)(C)C)cc1 | CN(C)C(=O)[C@H]1CC[C@@H](O)[C@H](NS(=O)(=O)NC(=O)OC(C)(C)C)C1.Cc1ccc(S(=O)(=O)Cl)cc1.Cn1ccnc1>ClCCl>Cc1ccc(S(=O)(=O)O[C@@H]2CC[C@H](C(=O)N(C)C)C[C@H]2NS(=O)(=O)NC(=O)OC(C)(C)C)cc1 |
US09447118B2 | 2,016 | CCN(CC)CC.CN(C)C(=O)[C@H]1CC[C@@H](O)[C@H](NS(=O)(=O)NC(=O)OC(C)(C)C)C1.CS(=O)(=O)Cl.ClCCl>O>CN(C)C(=O)[C@H]1CC[C@@H]2NS(=O)(=O)N(C(=O)OC(C)(C)C)[C@@H]2C1 | CCN(CC)CC.CN(C)C(=O)[C@H]1CC[C@@H](O)[C@H](NS(=O)(=O)NC(=O)OC(C)(C)C)C1.CS(=O)(=O)Cl.ClCCl>O>CN(C)C(=O)[C@H]1CC[C@@H]2NS(=O)(=O)N(C(=O)OC(C)(C)C)[C@@H]2C1 |
US09447118B2 | 2,016 | CN(C)C(=O)[C@H]1CC[C@H](N)[C@H](NC(=O)OC(C)(C)C)C1.O.O=C(O)C(=O)O>C(#N)C>CN(C)C(=O)[C@H]1CC[C@H](N)[C@H](NC(=O)OC(C)(C)C)C1.O=C(O)C(=O)O | CN(C)C(=O)[C@H]1CC[C@H](N)[C@H](NC(=O)OC(C)(C)C)C1.O.O=C(O)C(=O)O>C(#N)C>CN(C)C(=O)[C@H]1CC[C@H](N)[C@H](NC(=O)OC(C)(C)C)C1.O=C(O)C(=O)O |
US09447091B2 | 2,016 | Brc1cn[nH]c1.CN(C)CCCl.Cl.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>CN(C)CCn1cc(Br)cn1 | Brc1cn[nH]c1.CN(C)CCCl.Cl.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>CN(C)CCn1cc(Br)cn1 |
US09447091B2 | 2,016 | O=C1CCC(=O)N1I.O=S(=O)(O)C(F)(F)F.O=[N+]([O-])c1ccccc1F>>O=[N+]([O-])c1cc(I)ccc1F | O=C1CCC(=O)N1I.O=S(=O)(O)C(F)(F)F.O=[N+]([O-])c1ccccc1F>>O=[N+]([O-])c1cc(I)ccc1F |
US09447091B2 | 2,016 | O=Cc1ccc(F)cc1.O=[N+]([O-])O>S(=O)(=O)(O)O>O=Cc1ccc(F)c([N+](=O)[O-])c1 | O=Cc1ccc(F)cc1.O=[N+]([O-])O>S(=O)(=O)(O)O>O=Cc1ccc(F)c([N+](=O)[O-])c1 |
US09447091B2 | 2,016 | CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCN(CC)CC.OC1CCNCC1>C(Cl)Cl>CC(C)(C)OC(=O)N1CCC(O)CC1 | CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCN(CC)CC.OC1CCNCC1>C(Cl)Cl>CC(C)(C)OC(=O)N1CCC(O)CC1 |
US09447091B2 | 2,016 | CC(C)(O)CCBr.CCN(CC)CC.[N-]=[N+]=[N-].[Na+]>C(Cl)Cl.O>CC(C)(O)CCN=[N+]=[N-] | CC(C)(O)CCBr.CCN(CC)CC.[N-]=[N+]=[N-].[Na+]>C(Cl)Cl.O>CC(C)(O)CCN=[N+]=[N-] |
US09447091B2 | 2,016 | BrCC1CC1.Brc1cn[nH]c1.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>Brc1cnn(CC2CC2)c1 | BrCC1CC1.Brc1cn[nH]c1.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>Brc1cnn(CC2CC2)c1 |
US09447091B2 | 2,016 | CCOC(=O)CCl.CN1CCNCC1.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>CCOC(=O)CN1CCOCC1 | CCOC(=O)CCl.CN1CCNCC1.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>CCOC(=O)CN1CCOCC1 |
US09447091B2 | 2,016 | CCOC(=O)CN1CCOCC1>Cl>O=C(O)CN1CCOCC1 | CCOC(=O)CN1CCOCC1>Cl>O=C(O)CN1CCOCC1 |
US09447091B2 | 2,016 | CCN(CC)CC.CN1CCC(O)CC1.CS(=O)(=O)Cl>C(Cl)Cl>CN1CCC(OS(C)(=O)=O)CC1 | CCN(CC)CC.CN1CCC(O)CC1.CS(=O)(=O)Cl>C(Cl)Cl>CN1CCC(OS(C)(=O)=O)CC1 |
US09447091B2 | 2,016 | Brc1cn[nH]c1.CC(C)Br.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>CC(C)n1cc(Br)cn1 | Brc1cn[nH]c1.CC(C)Br.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>CC(C)n1cc(Br)cn1 |
US09447091B2 | 2,016 | CC(=O)[O-].CC(C)n1cc(Br)cn1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.N#N.[K+]>O1CCOCC1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2]>CC(C)n1cc(B2OC(C)(C)C(C)(C)O2)cn1 | CC(=O)[O-].CC(C)n1cc(Br)cn1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.N#N.[K+]>O1CCOCC1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2]>CC(C)n1cc(B2OC(C)(C)C(C)(C)O2)cn1 |
US09447091B2 | 2,016 | CC(=O)[O-].CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CCn1cc(Br)cn1.N#N.[K+]>O1CCOCC1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2]>CCn1cc(B2OC(C)(C)C(C)(C)O2)cn1 | CC(=O)[O-].CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CCn1cc(Br)cn1.N#N.[K+]>O1CCOCC1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2]>CCn1cc(B2OC(C)(C)C(C)(C)O2)cn1 |
US09447091B2 | 2,016 | II.Nc1ncccc1[N+](=O)[O-].[O-][I+3]([O-])([O-])O>C(O)(=O)C.O.S(=O)(=O)(O)O>Nc1ncc(I)cc1[N+](=O)[O-] | II.Nc1ncccc1[N+](=O)[O-].[O-][I+3]([O-])([O-])O>C(O)(=O)C.O.S(=O)(=O)(O)O>Nc1ncc(I)cc1[N+](=O)[O-] |
US09447091B2 | 2,016 | Cl.Nc1ncc(I)cc1[N+](=O)[O-].O.O=N[O-].[NH4+].[Na+].[OH-]>[Cu]Cl>O=[N+]([O-])c1cc(I)cnc1Cl | Cl.Nc1ncc(I)cc1[N+](=O)[O-].O.O=N[O-].[NH4+].[Na+].[OH-]>[Cu]Cl>O=[N+]([O-])c1cc(I)cnc1Cl |
US09447091B2 | 2,016 | CCOC(=O)CBr.CN1CCNCC1.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>CCOC(=O)CN1CCN(C)CC1 | CCOC(=O)CBr.CN1CCNCC1.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>CCOC(=O)CN1CCN(C)CC1 |
US09447091B2 | 2,016 | CCN1CCN(CC(=O)OC)CC1>Cl>CCN1CCN(CC(=O)O)CC1 | CCN1CCN(CC(=O)OC)CC1>Cl>CCN1CCN(CC(=O)O)CC1 |
US09447091B2 | 2,016 | CC(O)Br.CCN(CC)CC.NC1CC1.O=C=NS(=O)(=O)Cl>C(Cl)Cl>O=C1OCCN1S(=O)(=O)NC1CC1 | CC(O)Br.CCN(CC)CC.NC1CC1.O=C=NS(=O)(=O)Cl>C(Cl)Cl>O=C1OCCN1S(=O)(=O)NC1CC1 |
US09447091B2 | 2,016 | CC(=O)OC(C)=O.Nc1cn[nH]c1>>CC(=O)Nc1cn[nH]c1 | CC(=O)OC(C)=O.Nc1cn[nH]c1>>CC(=O)Nc1cn[nH]c1 |
US09447091B2 | 2,016 | CCOC(=O)CBr.O=C([O-])[O-].[K+].[K+].c1nc[nH]n1>CN(C=O)C>CCOC(=O)Cn1cncn1 | CCOC(=O)CBr.O=C([O-])[O-].[K+].[K+].c1nc[nH]n1>CN(C=O)C>CCOC(=O)Cn1cncn1 |
US09447091B2 | 2,016 | C1CCNC1.CCOC(=O)CBr.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>CCOC(=O)CN1CCCC1 | C1CCNC1.CCOC(=O)CBr.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>CCOC(=O)CN1CCCC1 |
US09447091B2 | 2,016 | CCOC(=O)CN1CCCC1>Cl>O=C(O)CN1CCCC1 | CCOC(=O)CN1CCCC1>Cl>O=C(O)CN1CCCC1 |
US09447091B2 | 2,016 | C1COCCN1.CCOC(=O)CBr.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>CCOC(=O)CN1CCOCC1 | C1COCCN1.CCOC(=O)CBr.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>CCOC(=O)CN1CCOCC1 |
US09447091B2 | 2,016 | CCOC(=O)CN1CCOCC1>Cl>O=C(O)CN1CCOCC1 | CCOC(=O)CN1CCOCC1>Cl>O=C(O)CN1CCOCC1 |
US09447091B2 | 2,016 | C1CCNCC1.CCOC(=O)CCl.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>CCOC(=O)CN1CCCCC1 | C1CCNCC1.CCOC(=O)CCl.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>CCOC(=O)CN1CCCCC1 |
US09447091B2 | 2,016 | CCOC(=O)CN1CCCCC1>Cl>O=C(O)CN1CCCCC1 | CCOC(=O)CN1CCCCC1>Cl>O=C(O)CN1CCCCC1 |
US09447091B2 | 2,016 | CC1CNCC(C)N1.CCOC(=O)CBr.O=C([O-])[O-].[K+].[K+]>C1COCC1>CCOC(=O)CN1CC(C)NC(C)C1 | CC1CNCC(C)N1.CCOC(=O)CBr.O=C([O-])[O-].[K+].[K+]>C1COCC1>CCOC(=O)CN1CC(C)NC(C)C1 |
US09447091B2 | 2,016 | CCN1CCNCC1.CCOC(=O)CBr.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>CCOC(=O)CN1CCN(CC)CC1 | CCN1CCNCC1.CCOC(=O)CBr.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>CCOC(=O)CN1CCN(CC)CC1 |
US09447091B2 | 2,016 | CCOC(=O)CN1CCN(CC)CC1>Cl>CCN1CCN(CC(=O)O)CC1 | CCOC(=O)CN1CCN(CC)CC1>Cl>CCN1CCN(CC(=O)O)CC1 |
US09447091B2 | 2,016 | Brc1cn[nH]c1.CC(C)Br.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>CC(C)n1cc(Br)cn1 | Brc1cn[nH]c1.CC(C)Br.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>CC(C)n1cc(Br)cn1 |
US09447091B2 | 2,016 | CC(=O)[O-].CC(C)n1cc(Br)cn1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.N#N.[K+]>O1CCOCC1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2]>CC(C)n1cc(B2OC(C)(C)C(C)(C)O2)cn1 | CC(=O)[O-].CC(C)n1cc(Br)cn1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.N#N.[K+]>O1CCOCC1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2]>CC(C)n1cc(B2OC(C)(C)C(C)(C)O2)cn1 |
US09447091B2 | 2,016 | CCOC(=O)CN1CCCCC1>Cl>O=C(O)CN1CCCCC1 | CCOC(=O)CN1CCCCC1>Cl>O=C(O)CN1CCCCC1 |
US09447091B2 | 2,016 | C1COCCN1.CCOC(=O)CCl.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>CCOC(=O)CN1CCOCC1 | C1COCCN1.CCOC(=O)CCl.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>CCOC(=O)CN1CCOCC1 |
US09447091B2 | 2,016 | CCOC(=O)CN1CCOCC1>Cl>O=C(O)CN1CCOCC1 | CCOC(=O)CN1CCOCC1>Cl>O=C(O)CN1CCOCC1 |
US09447091B2 | 2,016 | CCOC(=O)CN1CCCC1>Cl>O=C(O)CN1CCCC1 | CCOC(=O)CN1CCCC1>Cl>O=C(O)CN1CCCC1 |
US09447091B2 | 2,016 | Brc1cn[nH]c1.CC(C)(O)CCBr.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>CC(C)(O)CCn1cc(Br)cn1 | Brc1cn[nH]c1.CC(C)(O)CCBr.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>CC(C)(O)CCn1cc(Br)cn1 |
US09447091B2 | 2,016 | Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.N#N.O=C([O-])[O-].O=[N+]([O-])c1cc(Br)ccc1F.[Na+].[Na+]>O1CCOCC1.Cl[Pd](Cl)([P](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)[P](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1>Cn1cc(-c2ccc(F)c([N+](=O)[O-])c2)cn1 | Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.N#N.O=C([O-])[O-].O=[N+]([O-])c1cc(Br)ccc1F.[Na+].[Na+]>O1CCOCC1.Cl[Pd](Cl)([P](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)[P](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1>Cn1cc(-c2ccc(F)c([N+](=O)[O-])c2)cn1 |
US09447091B2 | 2,016 | BrC1CCCC1.Ic1cn[nH]c1.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>Ic1cnn(C2CCCC2)c1 | BrC1CCCC1.Ic1cn[nH]c1.O=C([O-])[O-].[K+].[K+]>CN(C=O)C>Ic1cnn(C2CCCC2)c1 |
US09447091B2 | 2,016 | CC(=O)[O-].CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Ic1cnn(C2CCCC2)c1.N#N.[K+]>CS(C)=O.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2]>CC1(C)OB(c2cnn(C3CCCC3)c2)OC1(C)C | CC(=O)[O-].CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Ic1cnn(C2CCCC2)c1.N#N.[K+]>CS(C)=O.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2]>CC1(C)OB(c2cnn(C3CCCC3)c2)OC1(C)C |
US09447091B2 | 2,016 | CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1(C)OB(c2ccc(N)nc2)OC1(C)C.CCN(CC)CC>C(Cl)Cl>CC(C)(C)OC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cn1 | CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1(C)OB(c2ccc(N)nc2)OC1(C)C.CCN(CC)CC>C(Cl)Cl>CC(C)(C)OC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cn1 |
US09447091B2 | 2,016 | CC1(C)C(=O)N(Br)C(=O)N1Br.O=[N+]([O-])c1cccc([N+](=O)[O-])c1>S(=O)(=O)(O)O>O=[N+]([O-])c1cc(Br)cc([N+](=O)[O-])c1 | CC1(C)C(=O)N(Br)C(=O)N1Br.O=[N+]([O-])c1cccc([N+](=O)[O-])c1>S(=O)(=O)(O)O>O=[N+]([O-])c1cc(Br)cc([N+](=O)[O-])c1 |
US09447091B2 | 2,016 | O=[N+]([O-])c1cc(Br)cc([N+](=O)[O-])c1>C(O)(=O)C.[Fe]>Nc1cc(Br)cc([N+](=O)[O-])c1 | O=[N+]([O-])c1cc(Br)cc([N+](=O)[O-])c1>C(O)(=O)C.[Fe]>Nc1cc(Br)cc([N+](=O)[O-])c1 |
US09447091B2 | 2,016 | CC(=O)OC(C)=O.Nc1cc(Br)cc([N+](=O)[O-])c1>>CC(=O)Nc1cc(Br)cc([N+](=O)[O-])c1 | CC(=O)OC(C)=O.Nc1cc(Br)cc([N+](=O)[O-])c1>>CC(=O)Nc1cc(Br)cc([N+](=O)[O-])c1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(Br)cc([N+](=O)[O-])c1.N#N.O=C([O-])[O-].OB(O)c1ccc(F)cc1F.[Na+].[Na+]>COCCOC.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2]>CC(=O)Nc1cc(-c2ccc(F)cc2F)cc([N+](=O)[O-])c1 | CC(=O)Nc1cc(Br)cc([N+](=O)[O-])c1.N#N.O=C([O-])[O-].OB(O)c1ccc(F)cc1F.[Na+].[Na+]>COCCOC.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2]>CC(=O)Nc1cc(-c2ccc(F)cc2F)cc([N+](=O)[O-])c1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc([N+](=O)[O-])c1>CO.C(OCC)(=O)C.[Pd]>CC(=O)Nc1cc(N)cc(-c2ccc(F)cc2F)c1 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc([N+](=O)[O-])c1>CO.C(OCC)(=O)C.[Pd]>CC(=O)Nc1cc(N)cc(-c2ccc(F)cc2F)c1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(N)cc(-c2ccc(F)cc2F)c1.O=[N+]([O-])c1cc(Br)ccc1F.[F-].[K+]>CN(C=O)C>CC(=O)Nc1cc(Nc2ccc(Br)cc2[N+](=O)[O-])cc(-c2ccc(F)cc2F)c1 | CC(=O)Nc1cc(N)cc(-c2ccc(F)cc2F)c1.O=[N+]([O-])c1cc(Br)ccc1F.[F-].[K+]>CN(C=O)C>CC(=O)Nc1cc(Nc2ccc(Br)cc2[N+](=O)[O-])cc(-c2ccc(F)cc2F)c1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(Nc2ccc(Br)cc2[N+](=O)[O-])cc(-c2ccc(F)cc2F)c1.[Cl-].[NH4+]>C1COCC1.O.[Zn]>CC(=O)Nc1cc(Nc2ccc(Br)cc2N)cc(-c2ccc(F)cc2F)c1 | CC(=O)Nc1cc(Nc2ccc(Br)cc2[N+](=O)[O-])cc(-c2ccc(F)cc2F)c1.[Cl-].[NH4+]>C1COCC1.O.[Zn]>CC(=O)Nc1cc(Nc2ccc(Br)cc2N)cc(-c2ccc(F)cc2F)c1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)c1.[Na+].[OH-]>C(O)C>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(N)cc(-c3ccc(F)cc3F)c2)cn1 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)c1.[Na+].[OH-]>C(O)C>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(N)cc(-c3ccc(F)cc3F)c2)cn1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)c1.O=S(=O)(Cl)C1CC1>>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(NS(=O)(=O)C3CC3)cc(-c3ccc(F)cc3F)c2)cn1 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)c1.O=S(=O)(Cl)C1CC1>>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(NS(=O)(=O)C3CC3)cc(-c3ccc(F)cc3F)c2)cn1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cnn(CCN(C)C)c4)ccc32)c1.[Na+].[OH-]>C(O)C>CN(C)CCn1cc(-c2ccc3c(c2)ncn3-c2cc(N)cc(-c3ccc(F)cc3F)c2)cn1 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cnn(CCN(C)C)c4)ccc32)c1.[Na+].[OH-]>C(O)C>CN(C)CCn1cc(-c2ccc3c(c2)ncn3-c2cc(N)cc(-c3ccc(F)cc3F)c2)cn1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cn(C)nn4)ccc32)c1.[Na+].[OH-]>C(O)C>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(N)cc(-c3ccc(F)cc3F)c2)nn1 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cn(C)nn4)ccc32)c1.[Na+].[OH-]>C(O)C>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(N)cc(-c3ccc(F)cc3F)c2)nn1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cnco4)ccc32)c1.[Na+].[OH-]>C(O)C>Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cnco4)ccc32)c1 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cnco4)ccc32)c1.[Na+].[OH-]>C(O)C>Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cnco4)ccc32)c1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-n4cccn4)ccc32)c1.[Na+].[OH-]>C(O)C>Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-n4cccn4)ccc32)c1 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-n4cccn4)ccc32)c1.[Na+].[OH-]>C(O)C>Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-n4cccn4)ccc32)c1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-n4cccn4)ccc32)c1.O=S(=O)(Cl)C1CC1>>O=S(=O)(Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-n4cccn4)ccc32)c1)C1CC1 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-n4cccn4)ccc32)c1.O=S(=O)(Cl)C1CC1>>O=S(=O)(Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-n4cccn4)ccc32)c1)C1CC1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cn(CCN(C)C)nn4)ccc32)c1.[Na+].[OH-]>C(O)C>CN(C)CCn1cc(-c2ccc3c(c2)ncn3-c2cc(N)cc(-c3ccc(F)cc3F)c2)nn1 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cn(CCN(C)C)nn4)ccc32)c1.[Na+].[OH-]>C(O)C>CN(C)CCn1cc(-c2ccc3c(c2)ncn3-c2cc(N)cc(-c3ccc(F)cc3F)c2)nn1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cn(CCN(C)C)nn4)ccc32)c1.O=S(=O)(Cl)C1CC1>>CN(C)CCn1cc(-c2ccc3c(c2)ncn3-c2cc(NS(=O)(=O)C3CC3)cc(-c3ccc(F)cc3F)c2)nn1 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cn(CCN(C)C)nn4)ccc32)c1.O=S(=O)(Cl)C1CC1>>CN(C)CCn1cc(-c2ccc3c(c2)ncn3-c2cc(NS(=O)(=O)C3CC3)cc(-c3ccc(F)cc3F)c2)nn1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cn(CCC(C)(C)O)nn4)ccc32)c1.[Na+].[OH-]>C(O)C>CC(C)(O)CCn1cc(-c2ccc3c(c2)ncn3-c2cc(N)cc(-c3ccc(F)cc3F)c2)nn1 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cn(CCC(C)(C)O)nn4)ccc32)c1.[Na+].[OH-]>C(O)C>CC(C)(O)CCn1cc(-c2ccc3c(c2)ncn3-c2cc(N)cc(-c3ccc(F)cc3F)c2)nn1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cn(CCC(C)(C)O)nn4)ccc32)c1.O=S(=O)(Cl)C1CC1>>CC(C)(O)CCn1cc(-c2ccc3c(c2)ncn3-c2cc(NS(=O)(=O)C3CC3)cc(-c3ccc(F)cc3F)c2)nn1 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cn(CCC(C)(C)O)nn4)ccc32)c1.O=S(=O)(Cl)C1CC1>>CC(C)(O)CCn1cc(-c2ccc3c(c2)ncn3-c2cc(NS(=O)(=O)C3CC3)cc(-c3ccc(F)cc3F)c2)nn1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-c2ccc(F)cc2)cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)c1.[Na+].[OH-]>C(O)C>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(N)cc(-c3ccc(F)cc3)c2)cn1 | CC(=O)Nc1cc(-c2ccc(F)cc2)cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)c1.[Na+].[OH-]>C(O)C>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(N)cc(-c3ccc(F)cc3)c2)cn1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-c2ccc(F)cc2)cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)c1.O=S(=O)(Cl)C1CC1>>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(NS(=O)(=O)C3CC3)cc(-c3ccc(F)cc3)c2)cn1 | CC(=O)Nc1cc(-c2ccc(F)cc2)cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)c1.O=S(=O)(Cl)C1CC1>>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(NS(=O)(=O)C3CC3)cc(-c3ccc(F)cc3)c2)cn1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-c2ccc(F)cc2)cc(-n2cnc3cc(-n4cccn4)ccc32)c1.[Na+].[OH-]>C(O)C>Nc1cc(-c2ccc(F)cc2)cc(-n2cnc3cc(-n4cccn4)ccc32)c1 | CC(=O)Nc1cc(-c2ccc(F)cc2)cc(-n2cnc3cc(-n4cccn4)ccc32)c1.[Na+].[OH-]>C(O)C>Nc1cc(-c2ccc(F)cc2)cc(-n2cnc3cc(-n4cccn4)ccc32)c1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(Br)cc([N+](=O)[O-])c1.Cc1ccc(B2OC(C)(C)C(C)(C)O2)o1.O.O=C([O-])[O-].[Na+].[Na+]>COCCOC.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2]>CC(=O)Nc1cc(-c2ccc(C)o2)cc([N+](=O)[O-])c1 | CC(=O)Nc1cc(Br)cc([N+](=O)[O-])c1.Cc1ccc(B2OC(C)(C)C(C)(C)O2)o1.O.O=C([O-])[O-].[Na+].[Na+]>COCCOC.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2]>CC(=O)Nc1cc(-c2ccc(C)o2)cc([N+](=O)[O-])c1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-c2ccc(C)o2)cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)c1.[K+].[OH-]>C(O)C.O.C(OCC)(=O)C>Cc1ccc(-c2cc(N)cc(-n3cnc4cc(-c5cnn(C)c5)ccc43)c2)o1 | CC(=O)Nc1cc(-c2ccc(C)o2)cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)c1.[K+].[OH-]>C(O)C.O.C(OCC)(=O)C>Cc1ccc(-c2cc(N)cc(-n3cnc4cc(-c5cnn(C)c5)ccc43)c2)o1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-c2ccc(C)o2)cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)c1.O=S(=O)(Cl)C1CC1>>Cc1ccc(-c2cc(NS(=O)(=O)C3CC3)cc(-n3cnc4cc(-c5cnn(C)c5)ccc43)c2)o1 | CC(=O)Nc1cc(-c2ccc(C)o2)cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)c1.O=S(=O)(Cl)C1CC1>>Cc1ccc(-c2cc(NS(=O)(=O)C3CC3)cc(-n3cnc4cc(-c5cnn(C)c5)ccc43)c2)o1 |
US09447091B2 | 2,016 | COC1CCC(OC)O1.Nc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>C(O)(=O)C>O=[N+]([O-])c1cc(-n2cccc2)cc([N+](=O)[O-])c1 | COC1CCC(OC)O1.Nc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>C(O)(=O)C>O=[N+]([O-])c1cc(-n2cccc2)cc([N+](=O)[O-])c1 |
US09447091B2 | 2,016 | COC1CCC(OC)O1.Nc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>C(O)C.O>Nc1cc(-n2cccc2)cc([N+](=O)[O-])c1 | COC1CCC(OC)O1.Nc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>C(O)C.O>Nc1cc(-n2cccc2)cc([N+](=O)[O-])c1 |
US09447091B2 | 2,016 | CC(=O)OC(C)=O.Nc1cc(-n2cccc2)cc([N+](=O)[O-])c1>>CC(=O)Nc1cc(-n2cccc2)cc([N+](=O)[O-])c1 | CC(=O)OC(C)=O.Nc1cc(-n2cccc2)cc([N+](=O)[O-])c1>>CC(=O)Nc1cc(-n2cccc2)cc([N+](=O)[O-])c1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-n2cccc2)cc([N+](=O)[O-])c1.[Ca+2].[Cl-].[Cl-]>C(O)C.O.[Fe]>CC(=O)Nc1cc(N)cc(-n2cccc2)c1 | CC(=O)Nc1cc(-n2cccc2)cc([N+](=O)[O-])c1.[Ca+2].[Cl-].[Cl-]>C(O)C.O.[Fe]>CC(=O)Nc1cc(N)cc(-n2cccc2)c1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(N)cc(-n2cccc2)c1.O=[N+]([O-])c1cc(Br)ccc1F.[F-].[K+]>CN(C=O)C>CC(=O)Nc1cc(Nc2ccc(Br)cc2[N+](=O)[O-])cc(-n2cccc2)c1 | CC(=O)Nc1cc(N)cc(-n2cccc2)c1.O=[N+]([O-])c1cc(Br)ccc1F.[F-].[K+]>CN(C=O)C>CC(=O)Nc1cc(Nc2ccc(Br)cc2[N+](=O)[O-])cc(-n2cccc2)c1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-n2cccc2)cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)c1.[Na+].[OH-]>C(O)C.C(OCC)(=O)C>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(N)cc(-n3cccc3)c2)cn1 | CC(=O)Nc1cc(-n2cccc2)cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)c1.[Na+].[OH-]>C(O)C.C(OCC)(=O)C>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(N)cc(-n3cccc3)c2)cn1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-n2cccc2)cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)c1.O=S(=O)(Cl)C1CC1>>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(NS(=O)(=O)C3CC3)cc(-n3cccc3)c2)cn1 | CC(=O)Nc1cc(-n2cccc2)cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)c1.O=S(=O)(Cl)C1CC1>>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(NS(=O)(=O)C3CC3)cc(-n3cccc3)c2)cn1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-n2cccc2)cc(-n2cnc3cc(-n4cccn4)ccc32)c1.[Na+].[OH-]>C(O)C.C(OCC)(=O)C>Nc1cc(-n2cccc2)cc(-n2cnc3cc(-n4cccn4)ccc32)c1 | CC(=O)Nc1cc(-n2cccc2)cc(-n2cnc3cc(-n4cccn4)ccc32)c1.[Na+].[OH-]>C(O)C.C(OCC)(=O)C>Nc1cc(-n2cccc2)cc(-n2cnc3cc(-n4cccn4)ccc32)c1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(N)cc(-n2cccc2)c1.O=[N+]([O-])c1cc(I)ccc1F.[F-].[K+]>CN(C=O)C>CC(=O)Nc1cc(Nc2ccc(I)cc2[N+](=O)[O-])cc(-n2cccc2)c1 | CC(=O)Nc1cc(N)cc(-n2cccc2)c1.O=[N+]([O-])c1cc(I)ccc1F.[F-].[K+]>CN(C=O)C>CC(=O)Nc1cc(Nc2ccc(I)cc2[N+](=O)[O-])cc(-n2cccc2)c1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-n2cccc2)cc(-n2cnc3cc(-c4cn(C)nn4)ccc32)c1.[Na+].[OH-]>C(O)C.C(OCC)(=O)C>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(N)cc(-n3cccc3)c2)nn1 | CC(=O)Nc1cc(-n2cccc2)cc(-n2cnc3cc(-c4cn(C)nn4)ccc32)c1.[Na+].[OH-]>C(O)C.C(OCC)(=O)C>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(N)cc(-n3cccc3)c2)nn1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-n2cccc2)cc(-n2cnc3cc(-c4cn(C)nn4)ccc32)c1.O=S(=O)(Cl)C1CC1>>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(NS(=O)(=O)C3CC3)cc(-n3cccc3)c2)nn1 | CC(=O)Nc1cc(-n2cccc2)cc(-n2cnc3cc(-c4cn(C)nn4)ccc32)c1.O=S(=O)(Cl)C1CC1>>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(NS(=O)(=O)C3CC3)cc(-n3cccc3)c2)nn1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-n2cccc2)cc(-n2cnc3cc(-c4cnco4)ccc32)c1.[Na+].[OH-]>C(O)C>Nc1cc(-n2cccc2)cc(-n2cnc3cc(-c4cnco4)ccc32)c1 | CC(=O)Nc1cc(-n2cccc2)cc(-n2cnc3cc(-c4cnco4)ccc32)c1.[Na+].[OH-]>C(O)C>Nc1cc(-n2cccc2)cc(-n2cnc3cc(-c4cnco4)ccc32)c1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-n2cccc2)cc(-n2cnc3cc(-c4cnco4)ccc32)c1.O=S(=O)(Cl)C1CC1>>O=S(=O)(Nc1cc(-n2cccc2)cc(-n2cnc3cc(-c4cnco4)ccc32)c1)C1CC1 | CC(=O)Nc1cc(-n2cccc2)cc(-n2cnc3cc(-c4cnco4)ccc32)c1.O=S(=O)(Cl)C1CC1>>O=S(=O)(Nc1cc(-n2cccc2)cc(-n2cnc3cc(-c4cnco4)ccc32)c1)C1CC1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-n2cccc2)cc(-n2cnc3cc(-c4cn(CCC(C)(C)O)nn4)ccc32)c1.[Na+].[OH-]>C(O)C>CC(C)(O)CCn1cc(-c2ccc3c(c2)ncn3-c2cc(N)cc(-n3cccc3)c2)nn1 | CC(=O)Nc1cc(-n2cccc2)cc(-n2cnc3cc(-c4cn(CCC(C)(C)O)nn4)ccc32)c1.[Na+].[OH-]>C(O)C>CC(C)(O)CCn1cc(-c2ccc3c(c2)ncn3-c2cc(N)cc(-n3cccc3)c2)nn1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(Br)cc([N+](=O)[O-])c1.O=C([O-])[O-].[Cs+].[Cs+].c1cn[nH]c1>CN(C=O)C.[Cu-]=O>CC(=O)Nc1cc(-n2cccn2)cc([N+](=O)[O-])c1 | CC(=O)Nc1cc(Br)cc([N+](=O)[O-])c1.O=C([O-])[O-].[Cs+].[Cs+].c1cn[nH]c1>CN(C=O)C.[Cu-]=O>CC(=O)Nc1cc(-n2cccn2)cc([N+](=O)[O-])c1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-n2cccn2)cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)c1.[Na+].[OH-]>C(O)C>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(N)cc(-n3cccn3)c2)cn1 | CC(=O)Nc1cc(-n2cccn2)cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)c1.[Na+].[OH-]>C(O)C>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(N)cc(-n3cccn3)c2)cn1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-n2cccn2)cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)c1.O=S(=O)(Cl)C1CC1>>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(NS(=O)(=O)C3CC3)cc(-n3cccn3)c2)cn1 | CC(=O)Nc1cc(-n2cccn2)cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)c1.O=S(=O)(Cl)C1CC1>>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(NS(=O)(=O)C3CC3)cc(-n3cccn3)c2)cn1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-n2cccn2)cc(-n2cnc3cc(-n4cccn4)ccc32)c1.[Na+].[OH-]>C(O)C>Nc1cc(-n2cccn2)cc(-n2cnc3cc(-n4cccn4)ccc32)c1 | CC(=O)Nc1cc(-n2cccn2)cc(-n2cnc3cc(-n4cccn4)ccc32)c1.[Na+].[OH-]>C(O)C>Nc1cc(-n2cccn2)cc(-n2cnc3cc(-n4cccn4)ccc32)c1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-n2cccn2)cc(-n2cnc3cc(-c4cnn(C5CCNCC5)c4)ccc32)c1.CS(=O)(=O)Cl.c1ccncc1>C(Cl)Cl>CC(=O)Nc1cc(-n2cccn2)cc(-n2cnc3cc(-c4cnn(C5CCN(S(C)(=O)=O)CC5)c4)ccc32)c1 | CC(=O)Nc1cc(-n2cccn2)cc(-n2cnc3cc(-c4cnn(C5CCNCC5)c4)ccc32)c1.CS(=O)(=O)Cl.c1ccncc1>C(Cl)Cl>CC(=O)Nc1cc(-n2cccn2)cc(-n2cnc3cc(-c4cnn(C5CCN(S(C)(=O)=O)CC5)c4)ccc32)c1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cnn(C)c4)cnc32)c1.[Na+].[OH-]>C(O)C>Cn1cc(-c2cnc3c(c2)ncn3-c2cc(N)cc(-c3ccc(F)cc3F)c2)cn1 | CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cnn(C)c4)cnc32)c1.[Na+].[OH-]>C(O)C>Cn1cc(-c2cnc3c(c2)ncn3-c2cc(N)cc(-c3ccc(F)cc3F)c2)cn1 |
US09447091B2 | 2,016 | CC(=O)Nc1cc(Br)cc([N+](=O)[O-])c1.N#N.O=C([O-])[O-].OB(O)c1cc(F)ccc1F.[Na+].[Na+]>COCCOC.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2]>CC(=O)Nc1cc(-c2cc(F)ccc2F)cc([N+](=O)[O-])c1 | CC(=O)Nc1cc(Br)cc([N+](=O)[O-])c1.N#N.O=C([O-])[O-].OB(O)c1cc(F)ccc1F.[Na+].[Na+]>COCCOC.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2]>CC(=O)Nc1cc(-c2cc(F)ccc2F)cc([N+](=O)[O-])c1 |